Actinomycosis

AB1_ACTINOMYCOSIS_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Primary healthcare outpatient: ICD-10 A42
  • Hospital discharge: ICD-10 A42
  • Hospital discharge: ICD-9 03[9]
  • Hospital discharge: ICD-8 113
  • Cause of death: ICD-10 A42
  • Cause of death: ICD-9 03[9]
  • Cause of death: ICD-8 113

3 out of 7 registries used, show all original rules.

162

4. Check minimum number of events

None

162

5. Include endpoints

None

162

6. Filter based on genotype QC (FinnGen only)

150

Control definitions (FinnGen only)

Control exclude
AB1_OTHER_BACTERIAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF13

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 150 79 71
Unadjusted period prevalence (%) 0.03 0.03 0.03
Median age at first event (years) 56.33 52.62 60.45

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
162
Matched controls
1620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
A42.8
ICD-10 Finland
Other forms of actinomycosis
+∞
42.6
39
*
A42.9
ICD-10 Finland
Actinomycosis, unspecified
+∞
32.4
30
*
A42.0
ICD-10 Finland
Pulmonary actinomycosis
+∞
30.1
28
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
55.1
30.1
35
8
A42.2
ICD-10 Finland
Cervicofacial actinomycosis
+∞
21.3
20
*
A41.9
ICD-10 Finland
Sepsis, unspecified
+∞
14.8
14
*
UGC12
NOMESCO Finland
Flexible bronchoscopy
6.3
14.6
27
50
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
+∞
13.7
13
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.1
13.6
32
74
A42.7
ICD-10 Finland
Actinomycotic sepsis
+∞
11.6
11
*
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
+∞
10.5
10
*
JN4BD
NOMESCO Finland
Extensive body CT
4.5
10.1
27
69
A46
ICD-10 Finland
Erysipelas
5.8
9.9
19
36
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.1
9.8
55
231
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.9
9.7
23
53
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.6
9.5
37
124
A42
ICD-10 Finland
Actinomycosis
+∞
8.4
8
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.9
8.2
27
80
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.5
7.8
79
442
K05.31
ICD-10 Finland
Periodontitis pronounced
3.6
7.5
27
85
11399
ICD-8 Finland
Actinomycosis
+∞
7.3
7
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
3.7
7.3
25
76
N02AA05
ATC
oxycodone; systemic
3.0
7.2
36
139
A06AD11
ATC
lactulose; oral
3.2
7.0
31
112
TGC00
NOMESCO Finland
Bronchial lavation
11.7
6.9
12
11
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.4
6.8
73
412
R50.9
ICD-10 Finland
Fever, unspecified
3.3
6.8
28
96
J01MA12
ATC
levofloxacin; systemic
2.9
6.8
36
144
NF1AA
NOMESCO Finland
Hip X-ray examination
4.0
6.7
20
55
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
9.3
6.7
13
15
C03CA01
ATC
furosemide; systemic
2.5
6.7
57
290
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
6.2
6.7
17
30
M04AA01
ATC
allopurinol; systemic
3.3
6.6
27
92
GD1AD
NOMESCO Finland
Thorax CT examination
6.5
6.5
16
27
A42.1
ICD-10 Finland
Abdominal actinomycosis
+∞
6.3
6
*
TLC02
NOMESCO Finland
Simple extraction of IUD
7.7
6.1
13
18
R2110
NOMESCO Finland
Giving the first information
4.3
6.1
16
40
SPAT1305
SPAT
Counselling and guidance related to physical exercise
3.5
6.0
22
70

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
42
131
3.98
12.13
3.9
2.0
—
—
—
0
0
29
71
4.76
11.44
1.4
2.8
—
—
—
0
0
56
239
3.05
9.69
7.9
3.1
—
—
—
0
0
19
37
5.68
9.62
9.6
1.6
—
—
—
0
0
89
491
2.80
9.50
7.8
3.3
33.01
36.25
g/l
3.74
83
455
25
64
4.44
9.27
2.4
1.5
1.00
1.27
g/l
0.75
25
58
106
685
2.58
7.60
16.8
7.9
4.11
3.91
e9/l
0.50
95
609
40
166
2.87
7.06
5.7
2.5
0.80
0.82
mmol/l
0.41
40
154
33
124
3.09
6.93
2.1
1.5
—
—
—
0
0
93
582
2.40
6.91
12.7
4.6
0.62
0.56
e9/l
1.37
83
519
93
583
2.40
6.87
12.7
4.6
0.04
0.04
e9/l
0.99
83
518
89
548
2.38
6.84
13.8
4.9
—
—
—
0
0
10
6
17.63
6.83
2.6
1.3
—
—
—
0
0
26
87
3.37
6.58
2.2
2.4
61.75
65.62
e9/l
0.35
18
63
94
604
2.33
6.40
13.2
4.7
1.75
1.94
e9/l
0.98
87
549
9
5
18.94
6.34
1.6
2.2
35.39
41.50
%
—
9
5
86
538
2.28
6.17
12.9
5.2
1.22
1.22
mmol/l
0.17
73
459
31
120
2.96
6.16
2.3
1.4
—
—
—
0
0
93
606
2.26
5.99
13.1
4.7
0.21
0.19
e9/l
0.65
88
553
94
619
2.24
5.85
12.4
5.1
10.82
10.70
umol/l
0.04
88
574
36
156
2.68
5.79
2.1
1.4
—
—
—
0
0
54
285
2.34
5.72
10.7
6.0
—
—
—
0
0
13
20
6.97
5.68
1.3
6.1
—
—
—
0
0
124
933
2.40
5.37
15.8
6.1
92.62
75.88
u/l
0.76
115
856
10
11
9.60
5.37
3.9
2.9
—
—
—
0
0
21
72
3.20
5.09
1.6
1.5
—
—
—
0
0
36
166
2.50
5.07
1.9
1.5
—
—
—
0
0
62
364
2.14
4.97
3.8
1.9
—
—
—
0
0
7
5
14.54
4.62
5.1
4.0
10.39
10.24
mg/l
—
7
5
11
19
6.13
4.53
1.4
1.4
—
—
—
0
0
69
436
2.01
4.44
5.7
3.5
32.74
57.44
ng/l
1.01
52
310
81
543
1.98
4.40
12.9
12.5
1.32
1.28
inr
0.08
20
151
8
9
9.27
4.33
1.5
1.1
—
—
—
0
0
11
22
5.28
4.08
1.2
1.2
—
—
—
0
0
37
190
2.23
4.05
2.2
2.0
—
—
—
0
0
42
228
2.14
4.01
2.9
1.4
2.84
2.58
g/l
0.27
34
138
27
121
2.48
4.01
10.5
6.4
104.00
103.74
mmol/l
0.13
27
121
117
921
1.97
3.66
6.4
3.6
18.47
10.46
mm/h
4.01
111
841
74
504
1.86
3.65
2.5
2.0
—
—
—
0
0
20
81
2.68
3.63
6.9
3.2
0.00
0.00
%
—
9
13
6
6
10.32
3.52
1.5
1.3
—
—
—
0
0
22
95
2.52
3.52
3.4
1.8
479.86
378.85
nmol/l
0.83
22
88
67
449
1.84
3.43
2.0
1.9
91.32
96.66
pmol/l
0.46
35
229
22
97
2.47
3.37
12.5
2.8
—
—
—
0
0
19
78
2.63
3.36
7.3
3.1
0.78
0.29
%
—
9
14
20
85
2.54
3.31
7.1
3.2
0.00
0.18
%
—
9
17
19
79
2.59
3.28
8.2
7.4
—
—
—
0
0
7
11
6.59
3.22
4.9
2.4
—
—
—
0
0
8
16
5.20
3.09
3.8
2.1
—
—
—
0
0
6
8
7.73
3.08
3.0
2.8
—
—
—
0
0
74
526
1.75
3.02
15.7
7.7
0.00
0.00
e9/l
0.05
60
442
19
83
2.46
2.97
6.5
6.3
1.13
1.37
mmol/l
0.52
19
83
39
229
1.93
2.95
4.3
2.5
2.46
2.44
mmol/l
0.30
31
208
20
90
2.39
2.94
7.2
3.1
0.80
0.70
%
—
10
22
59
396
1.77
2.92
6.6
2.8
2.34
2.36
mmol/l
0.45
50
355
7
13
5.57
2.90
2.3
1.2
—
—
—
0
0
21
98
2.31
2.86
1.9
1.3
—
—
—
0
0
51
330
1.80
2.84
3.7
2.7
—
—
—
0
0
8
18
4.62
2.83
5.8
2.3
4.98
3.97
e9/l
—
8
18
8
18
4.62
2.83
5.9
2.4
65.25
53.56
%
—
8
18
20
93
2.31
2.74
1.6
2.2
6.82
6.63
ug/l
0.02
14
83
6
10
6.18
2.72
1.0
4.3
—
—
—
0
0
50
327
1.77
2.67
4.9
3.6
—
—
—
0
0
39
237
1.85
2.65
3.2
2.2
5.08
5.35
e6/l
0.06
34
209
71
516
1.67
2.57
3.3
2.5
239.96
97.69
ug/l
1.95
63
470
7
16
4.52
2.50
1.6
1.7
—
—
—
0
0
39
242
1.81
2.47
1.7
1.7
1.52
0.87
mg/l
0.72
32
193
45
293
1.74
2.42
3.6
2.4
321.27
9328.43
umol/l
1.98
37
256
5
8
6.40
2.39
4.2
2.3
—
—
—
0
0
36
221
1.81
2.35
3.4
2.3
513.90
555.81
mosm/kgh2o
0.52
30
182
50
338
1.69
2.35
5.8
3.4
7.42
7.40
ph
0.67
11
62
7
18
4.01
2.28
5.9
1.9
—
—
—
0
0
5
9
5.69
2.23
1.4
1.0
—
—
—
0
0
8
24
3.45
2.21
2.0
1.6
115.00
130.60
ug/l
—
8
24
57
406
1.62
2.17
4.4
3.3
31.98
69.87
e6/l
1.01
42
280
5
10
5.12
2.08
1.6
1.2
—
—
—
0
0
5
10
5.12
2.08
1.0
1.0
—
—
—
0
0
5
10
5.12
2.08
1.4
1.6
—
—
—
0
0
7
20
3.61
2.08
1.1
1.4
—
—
—
0
0
9
32
2.92
2.03
2.2
1.3
—
—
—
0
0
9
33
2.83
1.96
1.1
1.3
—
—
—
0
0
6
16
3.85
1.95
1.0
1.1
—
—
—
0
0
137
1222
1.78
1.92
34.6
10.9
27.65
21.42
mg/l
1.27
117
925
13
59
2.31
1.90
9.1
5.1
27.06
25.02
mmol/l
0.81
13
59
46
322
1.60
1.85
3.9
2.7
0.16
0.36
e6/l
1.37
37
230
110
934
1.55
1.83
4.1
3.6
14.99
14.66
pmol/l
0.63
100
838
14
67
2.19
1.82
9.4
8.1
0.61
0.67
%
0.24
14
67
14
67
2.19
1.82
9.4
7.7
1.39
1.39
%
0.00
14
67
8
29
2.85
1.81
1.0
1.4
—
—
—
0
0
45
315
1.59
1.80
4.0
2.6
—
—
—
0
0
6
18
3.42
1.76
1.0
1.3
—
—
—
0
0
8
31
2.66
1.68
5.5
2.5
—
—
—
0
0
38
260
1.60
1.67
1.4
1.2
4.95
1.10
u/ml
0.45
11
72
85
694
1.47
1.64
6.7
3.9
6.65
6.50
mmol/l
0.27
85
638
102
864
1.49
1.63
3.9
3.6
—
—
—
0
0
5
14
3.65
1.62
1.0
1.1
—
—
—
0
0
16
85
1.98
1.61
6.2
2.7
3.62
2.12
mmol/l
0.84
16
73
5
15
3.40
1.53
1.6
1.1
—
—
—
0
0
10
45
2.30
1.49
2.0
1.7
—
—
—
0
0
9
39
2.38
1.45
6.6
3.8
—
—
—
0
0
9
39
2.38
1.45
1.2
1.4
—
—
—
0
0
5
16
3.19
1.45
1.0
1.2
—
—
—
0
0
36
253
1.54
1.41
5.4
3.6
—
—
—
0
0
71
573
1.43
1.39
4.6
3.5
0.00
0.00
estimate
-0.00
16
118
47
351
1.48
1.39
4.0
2.8
40.16
234.35
e6/l
0.51
37
260
6
23
2.67
1.38
3.8
1.8
7.18
8.60
kpa
—
6
23
6
23
2.67
1.38
3.8
1.8
5.52
5.01
kpa
—
6
23
97
829
1.42
1.37
6.4
3.9
—
—
—
0
0
5
17
3.00
1.37
1.0
1.1
—
—
—
0
0
9
42
2.21
1.36
1.1
1.4
—
—
—
0
0
9
42
2.21
1.36
1.2
1.4
—
—
—
0
0
9
42
2.21
1.36
1.3
1.4
—
—
—
0
0
26
172
1.61
1.31
2.7
2.8
1.69
2.55
e6/l
0.28
13
88
5
18
2.83
1.29
1.2
1.3
—
—
—
0
0
18
109
1.73
1.25
2.3
1.9
—
—
—
0
0
15
86
1.82
1.24
11.5
2.8
1.22
1.23
mmol/l
0.25
15
73
38
280
1.47
1.19
1.6
1.5
23.15
21.22
nmol/l
0.38
33
234
5
20
2.55
1.16
1.2
2.1
—
—
—
0
0
16
96
1.74
1.15
1.1
1.1
—
—
—
0
0
10
51
2.02
1.14
9.0
8.9
25.89
24.64
mmol/l
—
10
51
24
162
1.57
1.12
4.3
2.0
2.32
2.44
g/l
0.42
24
147
24
162
1.57
1.12
2.0
1.4
400.00
528.42
titre
—
7
38
11
60
1.89
1.05
1.3
1.1
—
—
—
0
0
15
91
1.71
1.04
4.1
3.0
—
—
—
0
0
7
34
2.11
1.04
6.7
3.9
4.11
3.92
mmol/l
—
7
34
69
579
1.33
1.00
6.0
4.7
0.00
0.00
estimate
-0.00
15
106
22
150
1.54
0.99
1.4
1.2
—
—
—
0
0
5
23
2.21
0.98
1.8
1.2
—
—
—
0
0
69
580
1.33
0.98
4.8
3.5
0.00
0.00
estimate
-0.00
13
107
7
36
1.99
0.98
1.7
1.3
1.09
1.19
g/l
—
7
36
7
36
1.99
0.98
3.1
1.3
0.20
0.24
g/l
—
7
36
6
29
2.11
0.90
3.0
1.4
83.50
90.76
pmol/l
—
6
29
8
43
1.90
0.89
1.3
1.4
—
—
—
0
0
6
109
0.53
0.75
1.5
1.5
—
—
—
0
0
5
24
2.12
0.75
1.2
1.2
—
—
—
0
0
5
26
1.95
0.71
4.0
2.0
—
—
—
0
0
122
1140
1.28
0.66
5.2
4.4
1.80
3.00
mu/l
0.58
114
1031
43
357
1.28
0.65
4.5
2.7
5.70
7.67
mmol/l
1.95
33
288
39
465
0.79
0.61
2.7
2.7
—
—
—
0
0
28
221
1.32
0.61
1.4
1.3
16.30
30.84
iu/ml
—
5
72
19
142
1.38
0.57
1.7
1.7
188.93
87.06
ug/g
0.92
14
109
37
307
1.27
0.56
5.9
3.8
0.00
0.01
estimate
0.50
14
108
39
331
1.23
0.49
5.0
2.9
89.82
238.92
mg/l
0.33
25
204
39
333
1.23
0.47
1.7
1.4
—
—
—
0
0
7
51
1.39
0.44
4.0
3.0
—
—
—
0
0
5
32
1.58
0.42
1.8
1.2
661.20
558.41
mg/l
—
5
32
0
16
0.00
0.41
0.0
1.0
—
0.18
—
0
7
8
60
1.35
0.41
1.6
1.6
—
—
—
0
0
28
235
1.23
0.39
1.3
1.9
440.63
456.62
pmol/l
0.12
19
195
40
350
1.19
0.38
6.1
3.4
18.18
6.18
mg/mmol
1.03
22
203
6
41
1.48
0.36
1.2
1.4
—
—
—
0
0
123
1274
0.86
0.32
5.3
4.8
2.81
2.77
mmol/l
0.17
114
1166
7
52
1.36
0.31
1.0
1.1
—
—
—
0
0
25
213
1.21
0.31
1.4
1.3
11.69
8.35
u/ml
—
8
92
7
53
1.33
0.31
1.0
1.1
—
—
—
0
0
11
84
1.33
0.31
8.9
3.6
—
—
—
0
0
21
248
0.82
0.30
2.6
2.9
0.66
0.75
ug/l
0.14
12
155
10
127
0.77
0.26
1.3
1.3
—
—
—
0
0
137
1334
1.17
0.26
33.5
13.2
85.50
75.28
umol/l
0.75
137
1334
30
336
0.87
0.24
4.0
3.0
—
—
—
0
0
122
1252
0.90
0.20
4.8
4.2
4.70
4.68
mmol/l
0.07
114
1157
121
1242
0.90
0.19
4.6
4.2
1.48
1.49
mmol/l
0.04
112
1141
38
409
0.91
0.16
6.9
4.8
1.43
2.03
ug/l
1.62
38
359
111
1081
1.09
0.15
28.6
13.8
15.54
14.92
%
0.43
106
1067
12
139
0.85
0.14
1.0
1.3
—
—
—
0
0
129
1314
0.91
0.14
27.8
10.4
—
—
—
0
0
13
114
1.15
0.12
1.5
1.3
—
—
—
0
0
7
65
1.08
0.08
3.6
3.6
4.52
4.66
pmol/l
—
7
59
8
77
1.04
0.07
4.1
2.7
—
—
—
0
0
7
80
0.87
0.07
1.4
1.2
—
—
—
0
0
17
158
1.08
0.06
1.1
1.3
—
—
—
0
0
34
327
1.05
0.05
1.6
1.6
1.30
1.30
mmol/l
0.02
25
279
114
1153
0.96
0.05
6.5
5.3
40.68
39.39
mmol/mol
0.64
109
1072
139
1400
0.95
0.04
44.1
16.8
7.03
6.56
e9/l
1.86
133
1363
139
1399
0.95
0.03
43.9
16.7
4.28
4.53
e12/l
6.35
133
1363
139
1398
0.96
0.02
44.3
16.8
38.06
40.64
%
4.08
134
1308
139
1396
0.97
0.00
43.7
16.8
269.35
248.95
e9/l
1.97
133
1363
123
1231
1.00
0.00
5.4
4.3
6.26
5.88
mmol/l
0.95
110
1128
11
113
0.97
0.00
1.8
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
9.20
—
0
5
8
85
0.94
0.00
1.4
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
6.5
—
0.58
—
0
8
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.2
—
68.11
—
0
9
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
8
83
0.96
-0.00
1.0
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
155.54
—
0
9
8
81
0.99
-0.00
6.6
4.0
—
—
—
0
0
120
1200
1.00
-0.00
4.3
3.8
1.33
1.27
mmol/l
0.34
110
1096
0
6
0.00
-0.00
0.0
3.3
—
7.58
—
0
6

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: AB1_ACTINOMYCOSIS_WIDE – Actinomycosis

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).