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This is a non-core endpoint: only basic statistics are computed.

Upper arm

Z21_UPPER_ARM

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 ZA2.0
  • Cause of death: ICD-10 ZA2.0

2 out of 7 registries used, show all original rules.

73

4. Check minimum number of events

None

73

5. Include endpoints

None

73

6. Filter based on genotype QC (FinnGen only)

73

Control definitions (FinnGen only)

Control exclude
Z21_ADDIT_CODES_LOCAT_DEFECT_INJURY_ILLNE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
Z[AB]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 73 35 38
Unadjusted period prevalence (%) 0.01 0.01 0.02
Median age at first event (years) 55.71 50.20 60.79

-FinnGen-

Age distribution of first events

020405060700246810121416AgeIndividuals

-FinnGen-

Year distribution of first events

197019751980198519901995200020102015202020230246810121416182022242628YearIndividuals

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
63
Matched controls
632
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
ZA2.0
ICD-10 Finland
Upper arm
+∞
90.4
63
*
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
14.5
6.9
11
9

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
87
4.09
7.12
4.0
2.7
97.68
250.97
ng/l
0.49
14
63
17
74
2.69
2.84
7.3
27.7
1.23
1.31
inr
—
12
9
12
48
2.80
2.32
2.8
2.3
1.88
5.40
ug/l
2.60
12
43
9
32
3.06
2.08
7.7
1.6
256.72
101.67
ng/l
—
9
27
27
168
1.96
1.92
2.3
3.2
28.55
77.44
e6/l
0.61
20
132
14
70
2.24
1.73
1.1
1.2
—
—
—
0
0
29
191
1.86
1.71
2.7
3.7
24.55
51.91
e6/l
0.44
20
137
7
25
2.98
1.69
1.3
1.3
—
—
—
0
0
54
435
1.93
1.64
3.7
3.7
14.28
14.75
pmol/l
0.71
48
392
47
367
1.79
1.53
6.8
10.0
4.22
3.85
e9/l
0.39
40
324
67
597
2.49
1.47
18.3
12.4
21.96
20.55
mg/l
0.15
52
470
16
92
1.95
1.39
1.3
1.2
22.68
6.76
u/ml
—
8
29
30
213
1.69
1.32
1.8
1.9
96.79
97.15
pmol/l
0.02
15
115
6
26
2.42
1.21
1.2
1.3
—
—
—
0
0
23
155
1.71
1.21
2.7
2.9
—
—
—
0
0
11
60
1.98
1.10
1.5
2.6
6.00
7.94
umol/l
0.36
11
51
45
368
1.58
1.06
3.8
3.8
—
24.67
—
0
6
21
144
1.64
1.02
3.2
4.8
—
—
—
0
0
0
30
0.00
1.00
0.0
1.3
—
—
—
0
0
15
96
1.71
0.93
2.1
3.6
2.50
2.45
mmol/l
0.53
15
80
14
90
1.69
0.86
2.0
2.0
—
—
—
0
0
0
25
0.00
0.80
0.0
1.8
—
—
—
0
0
25
189
1.49
0.79
2.6
2.3
—
—
—
0
0
21
153
1.52
0.79
3.5
3.9
—
—
—
0
0
31
247
1.44
0.75
5.6
7.1
1.21
1.21
mmol/l
0.01
26
205
37
305
1.43
0.75
5.8
6.1
12.98
10.95
umol/l
0.99
37
287
38
315
1.43
0.74
3.3
5.2
0.04
0.04
e9/l
0.52
33
276
59
636
0.62
0.73
15.6
11.8
—
—
—
0
0
20
147
1.50
0.72
2.0
3.3
0.47
0.19
e6/l
0.52
14
115
25
193
1.45
0.71
3.8
4.9
—
—
—
0
0
5
28
1.84
0.67
1.2
1.9
38.00
38.39
nmol/l
—
5
28
10
63
1.68
0.65
1.2
1.2
—
—
—
0
0
11
73
1.60
0.60
1.1
1.4
—
—
—
0
0
6
36
1.72
0.58
1.5
2.3
10.51
9.33
g/l
—
6
30
6
36
1.72
0.58
3.0
5.6
22.55
25.61
mmol/l
—
6
36
37
315
1.35
0.58
3.4
5.2
0.57
0.57
e9/l
0.03
32
276
6
97
0.58
0.57
1.3
1.6
—
—
—
0
0
29
239
1.35
0.55
2.4
2.0
—
—
—
0
0
45
401
1.32
0.48
4.2
3.9
—
—
—
0
0
60
560
1.40
0.45
15.5
13.1
40.96
40.08
%
0.35
44
424
18
142
1.36
0.44
2.1
3.0
—
—
—
0
0
5
32
1.60
0.43
1.2
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.1
—
5.18
—
0
6
0
15
0.00
0.41
0.0
3.3
—
26.56
—
0
8
9
66
1.41
0.40
1.8
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
4.9
—
24.90
—
0
18
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.3
—
275.71
—
0
9
10
72
1.45
0.39
1.9
1.6
—
—
—
0
0
6
43
1.43
0.36
1.3
5.0
—
—
—
0
0
13
164
0.75
0.35
3.7
3.0
—
—
—
0
0
67
641
1.55
0.35
20.9
14.5
75.27
78.88
umol/l
0.79
67
641
7
53
1.35
0.32
1.4
1.2
—
—
—
0
0
65
624
1.38
0.31
19.1
13.9
3.97
3.97
mmol/l
0.03
65
607
19
223
0.80
0.30
2.9
2.7
—
—
—
0
0
8
62
1.33
0.29
1.1
1.4
—
—
—
0
0
19
161
1.24
0.28
1.1
1.5
—
—
—
0
0
21
240
0.82
0.25
4.8
3.2
43.88
45.53
ng/l
0.02
11
152
5
37
1.38
0.24
6.2
3.7
—
—
—
0
0
5
38
1.34
0.24
1.0
1.2
—
—
—
0
0
5
39
1.30
0.23
1.0
1.2
—
—
—
0
0
5
39
1.30
0.23
1.0
1.2
—
—
—
0
0
5
39
1.30
0.23
1.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
61.64
—
0
11
0
10
0.00
0.21
0.0
3.8
—
8.10
—
0
10
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
21
235
0.85
0.19
4.2
4.7
1.67
1.98
ug/l
0.54
21
207
13
151
0.83
0.18
7.5
6.9
—
—
—
0
0
16
140
1.18
0.17
4.4
4.1
7.40
7.40
ph
—
5
25
6
75
0.78
0.16
1.0
6.6
1.08
1.10
mmol/l
—
6
68
38
403
0.88
0.16
3.3
3.7
—
—
—
0
0
19
170
1.16
0.15
2.5
4.0
2.06
13.16
mg/mmol
2.33
12
106
18
162
1.15
0.13
2.4
3.1
20.45
91.62
mg/l
1.96
11
108
6
58
1.04
0.08
1.3
1.9
284.17
415.00
nmol/l
—
6
52
8
91
0.86
0.07
2.4
2.3
15.38
13.46
umol/l
—
8
79
29
277
1.08
0.06
7.8
8.7
0.00
0.00
e9/l
0.48
24
220
12
111
1.10
0.04
1.3
2.0
—
—
—
0
0
12
111
1.10
0.04
1.8
2.8
663.25
600.46
mosm/kgh2o
0.32
12
94
13
138
0.93
0.03
4.3
3.3
—
—
—
0
0
22
219
1.01
0.00
22.0
6.2
1.34
1.18
inr
0.36
11
63
13
134
0.96
0.00
4.6
4.3
—
—
—
0
0
8
86
0.92
0.00
2.3
2.3
2.05
2.37
g/l
—
8
73
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
9
88
1.03
0.00
3.0
3.1
0.80
0.81
mmol/l
—
9
81
0
6
0.00
0.00
0.0
25.0
—
1491.33
—
0
6
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
10.5
—
955.00
—
0
6
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
69
0.86
0.00
1.5
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
4.5
—
0.57
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
5
56
0.89
0.00
2.2
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
3.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
3.5
—
105.00
—
0
8
0
7
0.00
0.00
0.0
2.6
—
1.61
—
0
7
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
5
50
1.00
0.00
5.0
7.6
—
—
—
0
0
5
58
0.85
0.00
1.8
1.5
—
—
—
0
0
5
59
0.84
0.00
1.4
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
6.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
3.5
—
4.01
—
0
8
0
6
0.00
0.00
0.0
3.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: Z21_UPPER_ARM – Upper arm

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).