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Other conjunctival vascular disorders and cysts

DOID EFO Endpoint Browser PheWeb

H7_CONJUVASC

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — H11.4
  • Hospital discharge: ICD-9 — 3727
  • Hospital discharge: ICD-8 — 37820
  • Cause of death: ICD-10 — H11.4
  • Cause of death: ICD-9 — 3727
  • Cause of death: ICD-8 — 37820

2 out of 7 registries used, show all original rules.

831

4. Check minimum number of events

None

831

5. Include endpoints

None

831

6. Filter based on genotype QC (FinnGen only)

831

Control definitions (FinnGen only)

Control exclude
H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H11
Name in latin
Aliae morbositates vasculares et cystae conjunctivae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5855 3365 2462
Only index persons 5436 3191 2245
Unadjusted period prevalence (%)
Whole population 0.08 0.10 0.07
Only index persons 0.10 0.12 0.09
Median age at first event (years)
Whole population 55.86 55.85 55.92
Only index persons 55.47 55.40 55.57

-FinnGen-

Key figures

All Female Male
Number of individuals 831 524 307
Unadjusted period prevalence (%) 0.16 0.18 0.14
Median age at first event (years) 56.29 54.49 59.37

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
738
Matched controls
7380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
4503599627370496.0
323.0
708
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
217.2
109.8
111
6
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.0
40.0
330
1575
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
34.6
380
2102
CBB30
NOMESCO Finland
Excision of lesion of eyelid
8.4
28.8
65
84
S01GX01
ATC
cromoglicic acid; ophthalmic
3.4
26.8
148
512
CFA20
NOMESCO Finland
Biopsy of conjunctiva
96.9
25.8
28
*
H04.10
ICD-10 Finland
Dry eye syndrome
3.7
22.5
106
321
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
25.4
19.6
27
11
37820
ICD-8 Finland
Other diseases of eye, Cysta conjunctivae
+∞
15.7
15
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.7
14.9
51
115
3727A
ICD-9 Finland
Disorders of conjunctiva, Conjunctival vascular disorders and cysts
+∞
14.6
14
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
13.3
137
671
H11.0
ICD-10 Finland
Pterygium
32.6
12.6
16
5
S01GX02
ATC
levocabastine; ophthalmic
4.3
12.1
45
111
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
8.9
12.1
25
29
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
11.3
95
415
F29
ICPC
Eye symptom/complaint other
2.7
11.0
76
300
H00.1
ICD-10 Finland
Chalazion
4.1
10.6
40
101
H10.4
ICD-10 Finland
Chronic conjunctivitis
111.5
10.4
11
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.9
10.0
40
106
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.5
9.8
80
345
M01AE02
ATC
naproxen; oral, rectal
1.6
9.5
405
3155
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
9.4
9
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.4
9.3
80
354
H15.1
ICD-10 Finland
Episcleritis
7.4
9.3
21
29
M03BX02
ATC
tizanidine; oral
1.6
9.2
443
3546
J05AB01
ATC
aciclovir; systemic
1.8
8.6
148
882
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.2
8.6
31
76
S01GX09
ATC
olopatadine; ophthalmic
7.5
8.5
19
26
XCK00
NOMESCO Finland
Perimetry
2.8
8.3
53
201
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
8.1
365
2836
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
8.0
130
755
J01DB01
ATC
cefalexin; oral
1.7
7.9
583
5102
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.1
7.9
90
456
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.2
7.9
40
131
S01GX08
ATC
ketotifen; ophthalmic
4.7
7.6
24
52
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
7.4
120
698
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
15.9
7.2
11
7
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
7.2
309
2355
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
7.1
484
4080
127
Kela drug reimbursment
Transplant complication
5.4
7.1
20
38
M25.5
ICD-10 Finland
Pain in joint
1.6
7.0
202
1393
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.2
6.8
34
111
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
22.7
6.7
9
*
H26.2
ICD-10 Finland
Complicated cataract
6.5
6.7
16
25
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.5
6.7
16
25
H01.0
ICD-10 Finland
Blepharitis
2.8
6.6
42
158
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.6
249
1834
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.5
341
2692
CBA10
NOMESCO Finland
Biopsy of eyelid
7.5
6.4
14
19
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
6.4
103
596
D07AC13
ATC
mometasone; topical
1.6
6.4
192
1335
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
11.1
6.3
11
10
S18
ICPC
Laceration/cut
1.5
6.3
289
2215
H57.1
ICD-10 Finland
Ocular pain
3.2
6.3
30
95
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
6.3
48
203
J01FA10
ATC
azithromycin; systemic
1.5
6.2
385
3138
J02AB02
ATC
ketoconazole; oral
3.7
6.2
25
69
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
6.1
375
3048
L04AD01
ATC
ciclosporin; systemic
4.4
6.1
20
46

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
635
5414
1.73
10.11
8.5
7.5
74.6
79.2
u/l
2.71
596
5067
370
2775
1.60
9.81
2.4
2.1
—
—
—
0
0
431
3455
1.51
7.88
6.9
6.6
1.2
1.2
mmol/l
0.64
360
2917
596
5131
1.57
7.75
5.1
4.1
11.1
12.5
mm/h
2.30
555
4730
17
39
4.43
6.98
1.9
2.1
13.4
12.8
%
—
9
18
714
6476
1.73
6.97
6.3
5.8
39.6
40.0
mmol/mol
0.45
646
6006
705
6388
1.68
6.72
5.6
4.7
1.9
1.9
mu/l
0.26
634
5805
212
1503
1.55
6.66
5.1
4.5
—
—
—
0
0
747
6883
1.84
6.65
17.5
14.1
20.7
23.6
mg/l
1.70
610
5412
739
6794
1.79
6.54
5.2
4.6
5.9
6.0
mmol/l
0.77
669
6165
757
7020
1.88
6.37
5.5
5.0
2.8
2.8
mmol/l
0.02
682
6443
607
5346
1.50
6.21
4.7
4.0
14.8
14.8
pmol/l
0.16
541
4832
474
3996
1.43
5.99
9.8
9.0
4.1
4.1
e9/l
0.09
426
3493
548
4746
1.45
5.98
4.9
4.3
—
—
—
0
0
374
3023
1.43
5.95
5.9
4.6
34.8
35.4
g/l
1.28
344
2824
424
3509
1.43
5.90
7.4
5.9
0.2
0.2
e9/l
0.74
375
3081
57
287
2.06
5.85
1.2
1.2
—
—
—
0
0
384
3151
1.41
5.46
6.5
5.9
1.2
1.2
mmol/l
0.17
348
2855
416
3464
1.40
5.42
7.3
5.7
1.8
1.9
e9/l
1.88
371
3035
407
3383
1.40
5.32
7.2
5.7
0.6
0.6
e9/l
0.08
362
2917
410
3414
1.40
5.30
4.9
3.7
0.0
0.0
estimate
0.80
83
607
241
1829
1.45
5.27
5.7
4.0
0.0
0.0
estimate
0.88
82
607
406
3380
1.39
5.23
6.0
5.0
0.0
0.0
estimate
0.50
82
624
195
1424
1.48
5.19
3.1
2.6
4.6
6.1
e6/l
1.13
178
1263
132
886
1.58
5.18
21.2
23.9
1.3
1.3
inr
0.07
21
116
740
6890
1.68
5.15
4.9
4.5
4.7
4.7
mmol/l
0.19
669
6364
736
6848
1.65
5.08
4.8
4.5
1.5
1.5
mmol/l
0.59
663
6278
403
3366
1.38
5.01
4.8
3.7
0.0
0.0
estimate
0.00
83
623
265
2063
1.42
4.99
5.2
3.9
7.4
7.4
ph
0.47
65
407
763
7173
1.78
4.99
20.0
16.3
139.8
139.7
mmol/l
0.70
747
6978
116
764
1.60
4.92
1.9
1.7
—
—
—
0
0
406
3404
1.38
4.89
7.2
5.7
0.0
0.0
e9/l
0.32
362
2942
764
7192
1.77
4.88
20.2
16.5
4.0
4.0
mmol/l
0.27
746
6987
261
2037
1.41
4.82
3.1
3.0
1694.2
1215.7
ng/l
0.81
226
1722
473
4080
1.37
4.70
5.2
4.6
6.6
6.7
mmol/l
0.32
445
3820
713
6610
1.55
4.70
4.4
4.0
1.3
1.3
mmol/l
0.33
641
6023
207
1570
1.42
4.45
4.9
3.6
—
—
—
0
0
297
2426
1.35
4.01
2.9
3.4
2.4
2.4
mmol/l
0.36
256
2126
513
4544
1.34
3.95
5.7
4.4
42.6
3356.6
e6/l
—
7
71
773
7360
1.72
3.93
13.0
10.4
24.8
25.6
u/l
0.81
748
7084
796
7646
1.98
3.91
25.8
20.8
91.3
91.2
fl
0.29
782
7528
222
1739
1.38
3.89
7.2
6.7
—
—
—
0
0
796
7648
1.97
3.87
25.9
20.9
4.5
4.5
e12/l
0.01
768
7427
139
1005
1.46
3.83
1.4
1.2
—
—
—
0
0
796
7651
1.96
3.82
26.0
21.0
134.6
134.5
g/l
0.04
782
7528
159
1183
1.43
3.76
1.2
1.3
209.1
33.4
iu/ml
0.46
39
389
84
547
1.60
3.75
3.8
3.5
89.8
81.6
ng/l
0.30
69
482
16
55
2.95
3.75
1.5
1.6
—
—
—
0
0
795
7644
1.92
3.72
26.0
20.9
254.4
251.3
e9/l
0.68
772
7443
795
7647
1.91
3.67
25.8
20.8
30.3
30.3
pg
0.14
781
7527
795
7648
1.91
3.65
25.9
20.9
6.6
6.7
e9/l
0.54
768
7423
346
2921
1.32
3.64
2.9
2.7
119.4
130.2
ug/l
0.38
316
2673
358
3039
1.31
3.61
12.0
9.5
0.0
0.0
e9/l
0.50
303
2491
90
602
1.56
3.59
3.5
3.9
1.2
1.2
mmol/l
0.75
79
528
217
1716
1.36
3.55
2.4
2.1
3.1
3.0
mg/l
0.18
188
1461
337
2843
1.31
3.53
8.4
9.2
1.2
1.2
inr
0.56
109
803
194
1510
1.37
3.51
1.3
1.3
0.7
2.1
u/ml
2.59
57
403
193
1501
1.37
3.51
1.7
1.6
0.9
1.2
mg/l
2.42
154
1157
377
3232
1.30
3.50
7.1
5.8
57.5
57.2
%
0.18
349
3021
382
3282
1.30
3.49
7.5
6.1
27.6
27.8
%
0.17
352
3058
322
2704
1.31
3.48
4.3
3.6
891.8
49.7
ng/l
0.48
223
1911
271
2223
1.33
3.46
2.9
2.4
52.8
57.2
u/l
1.90
249
2050
225
1796
1.35
3.46
2.7
2.6
6467.2
6965.8
umol/l
0.06
199
1559
375
3219
1.30
3.43
7.7
6.2
8.8
8.7
%
0.34
348
3013
89
602
1.54
3.39
4.5
4.3
0.9
1.0
%
0.07
29
182
278
2294
1.32
3.39
7.2
5.7
—
—
—
0
0
15
54
2.81
3.26
1.1
1.3
—
—
—
0
0
63
398
1.63
3.21
1.4
1.2
379.7
181.2
u/ml
0.40
57
368
371
3204
1.29
3.16
7.5
5.9
2.9
2.8
%
0.24
343
2981
132
981
1.41
3.13
2.3
2.3
2.4
2.3
g/l
0.23
125
914
171
1327
1.36
3.13
1.5
1.5
2.7
2.5
g/l
0.24
113
793
82
555
1.53
3.13
5.8
3.2
—
—
—
0
0
78
524
1.54
3.08
3.3
2.8
10.5
10.7
g/l
0.09
73
479
147
1120
1.38
3.01
3.6
3.3
0.8
0.8
mmol/l
0.16
137
1048
19
81
2.38
3.00
1.6
1.4
379.7
302.3
pmol/l
0.41
13
63
617
5706
1.32
2.99
20.1
17.4
13.7
13.7
%
0.14
604
5582
15
57
2.66
2.97
2.1
2.5
—
—
—
0
0
374
3251
1.27
2.97
4.0
4.0
—
—
—
0
0
79
537
1.52
2.96
4.5
4.5
0.0
0.7
%
0.65
21
145
8
17
4.74
2.92
4.5
4.1
—
—
—
0
0
123
917
1.40
2.87
1.4
1.3
338.0
508.5
titre
0.68
20
206
23
110
2.12
2.81
1.5
1.3
94.9
106.8
u/ml
—
6
18
358
3113
1.26
2.78
7.7
6.0
0.7
0.7
%
0.12
330
2901
249
2073
1.29
2.75
3.8
3.2
21.1
88.4
e6/l
1.40
203
1601
82
572
1.48
2.73
4.6
4.4
0.0
0.1
%
1.17
26
167
750
7175
1.46
2.73
16.2
13.4
—
—
—
0
0
230
1901
1.29
2.68
3.5
3.1
0.2
0.4
e6/l
2.15
189
1435
8
19
4.24
2.68
2.7
2.1
—
—
—
0
0
260
2186
1.28
2.64
3.3
3.1
6.9
7.2
mmol/l
0.59
212
1828
79
552
1.48
2.62
4.4
4.1
0.8
0.5
%
0.77
18
134
252
2115
1.27
2.59
2.3
2.1
161.0
237.7
u/l
1.09
236
1986
184
1486
1.31
2.54
5.8
4.0
1.0
1.0
kg/l
0.83
23
207
10
33
3.06
2.53
3.1
3.5
962.9
735.2
u/ml
—
10
33
7
16
4.40
2.48
1.0
1.0
—
—
—
0
0
170
1364
1.31
2.46
2.9
2.8
530.1
544.8
mosm/kgh2o
0.37
151
1173
112
846
1.37
2.43
1.6
1.5
—
—
—
0
0
284
2437
1.25
2.39
4.6
3.7
78.4
79.6
e6/l
0.02
217
1719
89
648
1.42
2.39
1.5
1.5
—
—
—
0
0
59
396
1.53
2.38
3.3
3.2
4.3
4.6
pmol/l
1.13
51
347
41
252
1.66
2.38
3.1
2.7
—
—
—
0
0
129
1000
1.34
2.37
2.4
2.1
—
—
—
0
0
8
22
3.66
2.37
1.0
1.1
1574.9
1792.5
miu/ml
—
8
22
166
1336
1.30
2.35
3.0
3.0
2.5
2.5
mmol/l
0.15
153
1181
254
2163
1.25
2.27
3.8
3.0
—
—
—
0
0
536
4943
1.24
2.26
4.3
3.8
—
—
—
0
0
220
1848
1.26
2.21
3.5
3.0
—
—
—
0
0
10
36
2.80
2.20
1.9
3.0
34.9
41.0
%
—
5
14
137
1084
1.32
2.19
2.3
2.3
13.9
12.9
umol/l
0.81
127
1007
24
129
1.89
2.19
4.7
3.7
55.9
57.9
%
0.32
24
129
103
782
1.36
2.18
1.4
1.3
—
—
—
0
0
16
74
2.18
2.15
1.2
1.1
—
—
nmol/l
—
0
0
116
899
1.34
2.15
6.3
5.0
1.0
1.0
mmol/l
0.35
110
826
17
81
2.12
2.14
1.3
1.4
33.7
29.3
u/l
0.20
12
69
107
820
1.35
2.13
2.1
2.2
164.2
127.2
ug/g
0.48
83
651
23
123
1.89
2.13
4.5
3.4
3.8
4.4
e9/l
0.89
23
123
23
123
1.89
2.13
1.7
1.3
—
—
—
0
0
103
786
1.35
2.11
2.7
2.4
1.7
1.8
%
0.60
93
706
8
25
3.22
2.10
4.4
3.0
—
—
—
0
0
84
622
1.39
2.07
4.9
3.2
2.5
2.1
mmol/l
0.47
69
498
326
2876
1.22
2.06
2.1
2.0
93.3
95.2
pmol/l
0.34
166
1450
256
2203
1.23
2.06
3.9
4.0
7.1
7.7
mg/mmol
0.10
160
1362
41
264
1.58
2.01
1.2
1.3
32.3
31.2
iu/l
0.08
36
224
409
3697
1.21
2.00
6.9
6.2
10.1
11.1
umol/l
2.12
387
3504
84
628
1.38
1.97
4.9
3.1
5.8
5.8
kpa
0.01
84
607
241
2071
1.23
1.95
3.3
3.2
383.3
230.2
mg/l
0.18
145
1302
75
551
1.40
1.95
6.7
8.2
—
—
—
0
0
81
603
1.38
1.95
2.2
2.6
66.8
71.1
e9/l
0.60
62
467
6
16
3.77
1.93
1.0
1.1
—
—
—
0
0
39
251
1.58
1.93
1.7
1.6
—
—
—
0
0
78
578
1.39
1.93
5.2
3.9
—
—
—
0
0
606
5707
1.23
1.89
22.4
18.5
331.5
331.8
g/l
0.30
600
5666
138
1116
1.28
1.89
1.2
1.3
1.9
11.9
u/ml
4.92
44
424
656
6231
1.25
1.88
16.3
15.3
39.5
39.4
%
0.05
448
4353
7
22
3.20
1.88
2.3
1.6
—
—
—
0
0
9
34
2.66
1.87
3.4
2.2
—
—
—
0
0
17
86
2.00
1.86
1.2
1.2
—
0.5
nmol/l
—
0
6
13
59
2.22
1.85
1.7
1.3
2.9
2.6
g/l
—
8
38
13
59
2.22
1.85
1.7
1.3
0.4
0.4
g/l
—
8
38
13
59
2.22
1.85
1.7
1.3
6.3
7.4
g/l
—
8
39
19
102
1.88
1.77
1.5
1.8
0.5
0.9
g/l
1.09
12
79
116
929
1.29
1.72
2.4
2.4
23.9
22.8
%
0.32
97
801
13
61
2.15
1.72
1.7
1.2
—
—
—
0
0
39
260
1.52
1.69
4.2
4.2
—
—
—
0
0
22
127
1.75
1.65
2.1
3.5
—
—
—
0
0
14
69
2.05
1.65
1.1
1.2
—
—
—
0
0
69
516
1.37
1.64
1.7
1.4
—
—
—
0
0
23
136
1.71
1.60
3.2
2.7
—
—
—
0
0
23
137
1.70
1.56
3.6
3.5
13.7
2090.8
u/ml
0.62
23
129
112
909
1.27
1.51
1.3
1.3
—
—
—
0
0
9
37
2.45
1.48
1.0
1.2
—
—
—
0
0
240
2113
1.19
1.48
4.1
3.8
—
—
—
0
0
10
45
2.24
1.47
1.6
2.0
—
—
—
0
0
213
1860
1.20
1.44
4.9
4.3
—
—
—
0
0
208
1816
1.19
1.40
1.4
1.4
—
—
—
0
0
93
745
1.28
1.40
1.5
1.6
—
—
—
0
0
153
1299
1.22
1.38
1.9
1.8
1307.4
1199.4
nmol/l
0.69
121
978
21
127
1.67
1.37
1.1
1.3
—
—
—
0
0
61
462
1.35
1.37
3.0
2.6
—
—
—
0
0
75
586
1.31
1.37
2.6
2.3
10.2
7.1
ug/l
0.26
67
511
15
82
1.84
1.36
1.3
1.2
—
—
—
0
0
5
17
2.95
1.36
1.0
1.8
—
—
—
0
0
247
2195
1.18
1.36
2.4
2.4
—
—
—
0
0
25
159
1.59
1.36
1.7
2.2
131.0
128.6
g/l
0.16
19
117
9
42
2.16
1.34
1.0
1.0
—
—
—
0
0
83
661
1.28
1.32
3.2
2.2
0.2
0.2
g/l
0.35
77
618
67
519
1.32
1.31
3.8
2.6
4.3
4.5
kpa
0.77
67
497
12
62
1.95
1.28
1.5
1.4
637702.1
175210.0
e6/l
—
7
42
10
48
2.10
1.28
2.1
1.9
24.1
20.7
nmol/l
—
10
43
27
180
1.52
1.22
1.0
1.1
—
—
—
0
0
17
102
1.68
1.17
1.9
2.0
33.3
32.5
pg
0.44
17
102
207
1835
1.17
1.17
4.3
3.4
—
—
—
0
0
0
33
0.00
1.16
0.0
1.5
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
62
485
1.30
1.15
2.4
2.2
—
—
—
0
0
7
30
2.34
1.12
1.3
1.5
1.3
1.1
nmol/l
—
7
24
7
30
2.34
1.12
4.0
2.4
—
—
—
0
0
38
277
1.39
1.11
1.9
2.0
2.2
2.5
ug/l
0.08
33
247
48
364
1.34
1.11
2.4
2.4
—
—
—
0
0
28
193
1.47
1.10
1.1
1.2
—
—
—
0
0
151
1314
1.18
1.07
3.9
3.7
339.6
419.8
ng/l
0.19
108
1038
27
188
1.45
1.02
1.2
1.2
—
—
—
0
0
40
302
1.34
0.97
1.5
1.8
1.6
1.5
g/l
0.14
35
271
25
174
1.45
0.96
3.6
4.3
7.4
7.4
ph
0.66
20
147
212
1912
1.15
0.95
5.3
5.0
2.3
2.6
ug/l
0.44
191
1695
94
793
1.21
0.94
5.4
8.1
5.0
5.1
kpa
0.92
86
764
110
942
1.19
0.94
1.9
1.7
—
—
—
0
0
16
101
1.60
0.94
1.6
1.2
—
—
—
0
0
93
785
1.21
0.93
5.5
8.2
0.7
1.3
mmol/l
0.87
69
631
12
70
1.72
0.93
1.5
2.2
—
—
—
0
0
25
176
1.43
0.91
1.3
1.2
—
3.3
—
0
15
191
1716
1.15
0.90
5.2
3.7
91.9
91.2
%
0.13
185
1675
29
212
1.38
0.87
4.3
8.8
1.5
1.3
mmol/l
0.32
24
188
23
161
1.44
0.87
1.7
1.7
9262.9
14174.0
e6/l
0.44
17
116
46
362
1.29
0.86
1.7
1.3
—
—
—
0
0
32
239
1.35
0.85
1.6
1.6
21.4
21.2
s
0.10
26
217
57
462
1.25
0.84
4.2
5.6
—
—
—
0
0
93
794
1.19
0.84
5.4
8.1
13.4
12.2
kpa
1.03
85
767
23
163
1.42
0.82
2.3
2.0
—
—
—
0
0
40
313
1.29
0.79
1.1
1.1
—
147.0
—
0
8
0
24
0.00
0.79
0.0
1.1
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
56.6
—
0
11
28
208
1.36
0.78
1.9
3.2
4.6
2.0
ratio
—
5
19
29
217
1.35
0.78
9.6
10.2
—
—
—
0
0
21
149
1.42
0.76
4.0
4.6
2.5
2.6
mmol/l
0.05
15
105
91
784
1.18
0.76
3.9
4.1
9.8
32.5
ug/l
1.18
73
647
11
67
1.65
0.75
4.9
3.3
70.7
54.0
%
—
6
50
5
25
2.01
0.72
1.2
1.5
—
—
—
0
0
29
220
1.33
0.72
1.0
1.1
—
—
—
0
0
23
168
1.38
0.72
1.1
1.3
695.0
497.1
mg/l
0.63
23
157
21
151
1.40
0.71
3.2
4.3
—
—
—
0
0
167
1513
1.13
0.71
1.7
1.7
41353829.8
32237805.1
pmol/l
0.08
133
1247
7
41
1.71
0.70
2.1
3.3
—
—
—
0
0
17
118
1.45
0.69
1.1
1.6
—
—
—
0
0
10
61
1.65
0.68
1.2
1.0
4.0
1.0
u/ml
—
5
19
18
127
1.43
0.68
1.3
1.6
—
—
—
0
0
21
153
1.38
0.67
2.3
2.6
16.2
16.1
%
0.04
12
79
24
179
1.35
0.67
2.1
1.5
302.1
298.9
mu/l
0.03
24
158
81
700
1.17
0.66
3.9
3.9
—
—
—
0
0
22
162
1.37
0.66
2.0
3.6
—
—
—
0
0
45
367
1.24
0.66
3.1
3.5
—
—
—
0
0
124
1108
1.14
0.66
3.2
3.0
0.8
0.8
ug/l
0.08
91
734
10
62
1.62
0.65
1.0
1.1
—
—
—
0
0
15
103
1.46
0.65
1.4
1.5
—
—
—
0
0
74
638
1.18
0.63
1.5
1.4
—
—
—
0
0
91
798
1.16
0.63
3.5
2.6
9.8
8.4
umol/l
0.20
77
701
26
200
1.31
0.61
2.8
3.4
—
—
—
0
0
182
1676
1.11
0.59
1.5
1.6
23.2
20.9
nmol/l
0.76
154
1414
182
1677
1.11
0.59
2.3
2.3
—
—
—
0
0
47
393
1.21
0.57
2.3
2.3
12.5
12.9
nmol/l
0.08
42
347
6
36
1.67
0.56
1.5
1.1
—
—
—
0
0
6
37
1.63
0.55
2.2
1.6
—
—
—
0
0
13
90
1.45
0.55
1.1
1.2
—
—
—
0
0
13
90
1.45
0.55
1.2
1.2
—
—
—
0
0
24
186
1.30
0.55
1.3
1.3
—
—
—
0
0
16
116
1.39
0.54
1.2
1.9
156.1
220.2
pmol/l
1.66
16
107
11
74
1.49
0.53
3.7
1.4
—
—
—
0
0
53
453
1.18
0.52
1.9
2.8
3.6
4.1
e9/l
0.74
38
355
16
118
1.36
0.50
1.6
2.0
—
—
—
0
0
42
354
1.20
0.49
4.0
2.7
0.2
0.2
e6/l
0.02
42
345
21
163
1.30
0.48
1.0
1.7
—
—
—
0
0
7
111
0.63
0.48
1.0
1.1
—
—
—
0
0
75
668
1.13
0.45
1.9
1.5
—
—
—
0
0
54
470
1.16
0.45
1.4
1.2
—
—
—
0
0
61
536
1.15
0.44
1.1
1.2
—
—
—
0
0
12
86
1.40
0.44
1.2
1.1
0.3
1.9
u/ml
—
6
29
11
78
1.42
0.43
1.4
1.6
54.7
62.3
%
—
6
52
33
391
0.84
0.42
1.5
1.4
—
—
—
0
0
10
70
1.43
0.42
1.2
1.1
0.2
1.0
u/ml
—
5
24
8
58
1.38
0.41
1.3
1.4
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
8
59
1.36
0.41
2.1
1.3
—
—
—
0
0
11
79
1.40
0.41
1.5
1.3
—
—
—
0
0
22
177
1.25
0.40
1.3
1.3
196.7
219.6
miu/ml
0.10
12
79
8
60
1.34
0.40
1.0
1.1
—
—
—
0
0
7
103
0.68
0.39
1.1
1.1
—
15.3
—
0
6
36
308
1.18
0.38
2.0
1.8
—
—
—
0
0
12
89
1.35
0.38
3.5
2.6
—
—
—
0
0
8
113
0.71
0.37
1.4
1.4
—
—
—
0
0
5
37
1.35
0.37
1.8
2.4
—
—
—
0
0
50
565
0.88
0.36
1.4
1.4
—
—
—
0
0
9
70
1.29
0.36
1.3
1.3
—
—
—
0
0
9
70
1.29
0.36
1.3
1.4
—
—
—
0
0
9
70
1.29
0.36
1.2
1.4
—
—
—
0
0
5
79
0.63
0.35
1.0
1.1
—
—
—
0
0
6
42
1.43
0.35
1.7
3.1
—
—
—
0
0
52
462
1.13
0.35
4.0
3.3
7.5
7.4
ph
—
7
61
7
52
1.35
0.31
1.9
2.3
2.0
2.1
ug/l
—
7
43
7
53
1.32
0.31
3.6
1.6
0.9
1.0
g/l
—
7
53
56
505
1.12
0.31
1.4
1.3
—
—
—
0
0
17
138
1.24
0.30
1.8
2.0
8104.7
1853.0
u/l
—
6
56
41
363
1.14
0.30
6.7
11.4
—
—
—
0
0
12
93
1.29
0.30
2.6
2.8
—
—
—
0
0
7
55
1.28
0.30
1.0
1.1
—
—
—
0
0
87
805
1.09
0.29
1.8
1.5
—
—
—
0
0
8
106
0.75
0.29
1.0
1.0
—
—
—
0
0
8
62
1.29
0.28
1.0
1.1
—
—
—
0
0
18
150
1.20
0.26
1.6
1.8
55.4
40.7
nmol/l
0.76
18
143
197
1888
1.06
0.26
1.7
1.7
1.4
1.4
mmol/l
0.21
160
1570
5
71
0.70
0.26
1.6
1.3
—
—
—
0
0
23
197
1.17
0.26
4.0
4.3
—
—
—
0
0
9
72
1.25
0.25
1.4
1.5
—
—
—
0
0
15
123
1.22
0.25
1.1
1.5
—
—
—
0
0
12
148
0.81
0.24
5.9
2.6
—
—
—
0
0
20
171
1.17
0.23
1.3
1.2
—
—
—
0
0
5
40
1.25
0.22
1.2
1.3
—
—
—
0
0
5
42
1.19
0.21
1.0
1.3
4.3
6.3
u/l
—
5
33
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
6.8
—
0
12
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.1
—
8.5
—
0
10
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
13
155
0.84
0.20
1.0
1.5
0.6
0.9
nmol/l
—
8
129
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
3.0
—
0
14
6
53
1.13
0.18
1.8
1.1
—
—
—
0
0
36
328
1.10
0.18
2.1
1.7
—
—
—
0
0
25
279
0.89
0.18
1.1
1.1
—
—
—
0
0
7
62
1.13
0.17
1.1
1.8
—
1.3
—
0
5
22
196
1.13
0.16
1.1
1.2
—
475.7
—
0
7
8
69
1.16
0.16
1.8
2.2
—
—
—
0
0
9
80
1.13
0.15
4.2
3.1
—
—
—
0
0
16
140
1.15
0.15
1.4
1.6
—
—
—
0
0
9
81
1.11
0.15
1.8
1.6
—
—
—
0
0
9
81
1.11
0.15
1.8
1.6
—
—
—
0
0
9
81
1.11
0.15
1.8
1.6
—
—
—
0
0
9
81
1.11
0.15
1.8
1.6
—
—
—
0
0
10
84
1.19
0.14
3.6
4.0
—
—
—
0
0
8
99
0.81
0.13
1.5
1.2
—
—
—
0
0
27
249
1.09
0.12
2.7
3.2
0.4
0.2
g/l
0.37
11
91
11
95
1.16
0.11
2.2
2.1
90.4
90.1
%
0.08
11
95
12
105
1.14
0.11
1.6
1.1
—
—
—
0
0
19
174
1.09
0.09
1.4
1.6
—
—
—
0
0
6
54
1.11
0.09
1.3
1.4
—
—
—
0
0
6
54
1.11
0.09
4.7
3.2
—
—
—
0
0
12
107
1.12
0.08
1.2
1.7
—
—
—
0
0
19
175
1.09
0.08
1.4
1.6
—
—
—
0
0
10
113
0.88
0.08
6.3
1.7
60.1
62.1
%
—
10
113
6
72
0.83
0.07
1.0
1.1
—
—
—
0
0
19
176
1.08
0.07
1.4
1.6
—
—
—
0
0
8
78
1.03
0.07
1.0
1.2
—
—
—
0
0
7
83
0.84
0.07
1.0
1.1
—
—
—
0
0
7
83
0.84
0.07
1.0
1.1
—
—
—
0
0
9
84
1.07
0.07
1.8
1.8
—
—
—
0
0
19
177
1.08
0.06
1.4
1.6
—
—
—
0
0
111
1088
1.02
0.06
3.2
2.9
2.1
2.6
e6/l
0.30
63
589
22
208
1.06
0.05
1.6
1.5
278.7
291.8
ug/g
0.10
13
121
16
150
1.07
0.04
5.5
3.6
18.4
25.5
mg/l
—
10
94
13
122
1.07
0.02
1.2
1.2
—
—
—
0
0
17
162
1.05
0.02
2.9
1.7
3.2
4.2
iu/l
—
8
49
42
429
0.98
0.02
1.6
1.5
—
—
—
0
0
14
144
0.97
0.00
2.4
2.8
0.9
0.9
nmol/l
—
9
111
17
166
1.02
0.00
1.5
1.6
—
—
—
0
0
12
123
0.98
0.00
2.2
1.3
—
—
—
0
0
34
343
0.99
0.00
4.5
3.3
—
—
—
0
0
43
427
1.01
0.00
1.5
1.4
—
—
—
0
0
241
2414
1.00
0.00
3.3
2.9
—
—
—
0
0
46
462
1.00
0.00
1.2
1.2
93.5
143.5
iu/ml
0.77
17
187
6
63
0.95
0.00
1.3
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.0
—
—
—
0
0
8
80
1.00
0.00
1.1
2.6
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
7
79
0.89
0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
5.9
—
0.3
—
0
7
9
94
0.96
0.00
2.1
2.7
3.9
4.0
mmol/l
—
9
94
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
0.00
2.1
2.7
104.1
105.4
mmol/l
—
9
94
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
9.2
—
—
—
0
0
17
170
1.00
0.00
2.6
2.5
134.1
94.0
ug/min
—
9
105
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
7
76
0.92
0.00
1.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.6
—
—
—
0
0
8
87
0.92
0.00
1.3
1.1
—
—
—
0
0
9
93
0.97
0.00
2.1
2.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
6
69
0.87
0.00
1.3
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
—
—
0
0
7
71
0.99
0.00
1.0
1.2
—
—
—
0
0
7
75
0.93
0.00
1.7
2.5
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint H7_CONJUVASC and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONJUVASC 0.92 [0.81, 1.05] 0.219
Birth year 0.994 [0.99, 1.0] 0.16

During the follow-up period (1.1.1998 — 31.12.2019), 359 out of 2876 females with H7_CONJUVASC died.

Males

Parameter HR [95% CI] p-value
H7_CONJUVASC 0.928 [0.81, 1.06] 0.266
Birth year 0.985 [0.98, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 388 out of 2074 males with H7_CONJUVASC died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONJUVASC.

N-year risk Females Males
1 0.071% 0.187%
5 0.519% 1.012%
10 1.248% 2.506%
15 2.497% 4.787%
20 4.41% 8.114%

Relationships between endpoints

↥

Index endpoint: H7_CONJUVASC – Other conjunctival vascular disorders and cysts

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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