No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
875 |
4. Check minimum number of eventsNone |
875 |
5. Include endpointsNone |
875 |
6. Filter based on genotype QC (FinnGen only) |
846 |
Control definitions (FinnGen only)
- Control exclude
- H7_CONJUNCTIVA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H11
- Name in latin
- Aliae morbositates vasculares et cystae conjunctivae
Similar endpoints
↥List of similar endpoints to
Other conjunctival vascular disorders and cysts
based on the number of shared cases.
Similar with more cases:
- Other disorders of conjunctiva
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5855 | 3365 | 2462 |
| Only index persons | 5436 | 3191 | 2245 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.07 |
| Only index persons | 0.10 | 0.12 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 55.86 | 55.85 | 55.92 |
| Only index persons | 55.47 | 55.40 | 55.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 846 | 545 | 301 |
| Unadjusted period prevalence (%) | 0.17 | 0.19 | 0.14 |
| Median age at first event (years) | 56.57 | 55.22 | 59.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 875
- Matched controls
- 8750
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
4503599627370496.0
307.7
845
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
217.7
128.4
130
7
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
22.6
52.8
39
18
CBB30
NOMESCO Finland
Excision of lesion of eyelid
7.2
50.0
78
118
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
45.1
477
2692
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.7
45.0
396
2040
S01GX01
ATC
cromoglicic acid; ophthalmic
3.3
39.9
184
662
H04.10
ICD-10 Finland
Dry eye syndrome
3.3
32.9
141
482
CFA20
NOMESCO Finland
Biopsy of conjunctiva
107.0
28.8
31
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.2
24.2
66
165
H15.1
ICD-10 Finland
Episcleritis
7.0
18.3
28
41
F29
ICPC
Eye symptom/complaint other
2.7
18.3
105
418
H11.0
ICD-10 Finland
Pterygium
53.7
18.0
21
*
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
97.1
17.6
19
*
H00.1
ICD-10 Finland
Chalazion
3.9
16.8
50
133
37820
ICD-8 Finland
Other diseases of eye, Cysta conjunctivae
+∞
15.7
15
*
127
Kela drug reimbursment
Transplant complication
6.3
15.5
26
42
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
11.1
15.1
28
26
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.9
15.0
44
116
S01GX02
ATC
levocabastine; ophthalmic
3.5
14.9
52
155
3727A
ICD-9 Finland
Disorders of conjunctiva, Conjunctival vascular disorders and cysts
+∞
14.6
14
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.4
14.6
109
491
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.0
14.5
174
950
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
14.1
106
479
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
13.6
13
*
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
13.2
171
955
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.4
13.0
47
143
L04AA06
ATC
mycophenolic acid; systemic
5.0
12.7
27
55
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
131.8
12.5
13
*
H57.1
ICD-10 Finland
Ocular pain
3.5
12.3
42
123
H01.0
ICD-10 Finland
Blepharitis
2.8
12.3
64
242
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.0
12.1
53
182
H10.4
ICD-10 Finland
Chronic conjunctivitis
47.3
11.9
14
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
11.8
313
2166
H53.1
ICD-10 Finland
Subjective visual disturbances
2.6
11.6
71
291
M03BX02
ATC
tizanidine; oral
1.7
11.6
540
4308
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.6
11.1
66
267
N03AX16
ATC
[U] pregabalin
1.8
11.1
214
1352
L04AD01
ATC
ciclosporin; systemic
4.8
10.8
24
51
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.1
10.7
45
151
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
10.7
608
5052
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.8
10.7
175
1052
XCK00
NOMESCO Finland
Perimetry
2.6
10.6
63
255
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
10.4
175
1060
SFA20
NOMESCO Finland
Two-surface restoration
1.6
10.3
492
3901
E0000UV, ,
ATC
1.6
10.2
341
2483
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
10.0
379
2840
H20.1
ICD-10 Finland
Chronic iridocyclitis
8.9
9.8
20
23
J01DB01
ATC
cefalexin; oral
1.8
9.8
706
6156
SAA02
NOMESCO Finland
Basic examination of mouth
1.6
9.8
550
4505
S01GX08
ATC
ketotifen; ophthalmic
3.7
9.7
31
87
SFA10
NOMESCO Finland
One-surface restoration
1.6
9.7
464
3659
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.6
9.4
460
3635
XCK10
NOMESCO Finland
Photography of fundus of eye
2.1
9.3
91
457
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
8.9
347
2596
M25.5
ICD-10 Finland
Pain in joint
1.6
8.8
277
1972
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
2.4
8.8
58
247
L03
ICPC
Low back symptom/complaint
1.6
8.7
234
1602
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.0
8.7
102
547
K02.1
ICD-10 Finland
Caries of dentine
1.5
8.7
480
3869
WX110
NOMESCO Finland
Infiltration anesthesia
1.6
8.7
595
5029
M01AE02
ATC
naproxen; oral, rectal
1.5
8.6
481
3882
R01AD12
ATC
fluticasone furoate; nasal
1.6
8.5
249
1739
H15.0
ICD-10 Finland
Scleritis
27.8
8.5
11
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
8.5
186
1209
SHB00
NOMESCO Finland
Preparing and fitting the occlusal splint in the mouth
2.1
8.4
81
404
S01BA04
ATC
prednisolone; ophthalmic
3.8
8.4
25
67
H10.5
ICD-10 Finland
Blepharoconjunctivitis
4.9
8.4
18
37
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
10.9
8.3
15
14
Z94.0
ICD-10 Finland
Kidney transplant status
7.6
8.2
18
24
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
8.1
195
1297
CD2S4
NOMESCO Finland
Photography of eye
11.8
8.1
14
12
H02AB04
ATC
methylprednisolone; systemic
1.8
8.0
124
728
S01GX09
ATC
olopatadine; ophthalmic
4.1
7.8
21
52
H00.00
ICD-10 Finland
Hordeolum
2.7
7.8
41
156
A02BC02
ATC
pantoprazole; systemic
1.5
7.8
574
4865
H02AB06
ATC
prednisolone; systemic
1.5
7.7
384
3004
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.1
7.6
68
330
R06AX27
ATC
desloratadine; oral
1.6
7.5
213
1474
S18
ICPC
Laceration/cut
1.5
7.4
385
3029
S01GX05
ATC
lodoxamide; ophthalmic
11.0
7.3
13
12
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
9.5
7.3
14
15
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
7.2
315
2388
M54.5
ICD-10 Finland
Low back pain
1.5
7.2
297
2225
CF2S4
NOMESCO Finland
Photography of conjunctiva
30.3
7.2
9
*
S01BC03
ATC
diclofenac; ophthalmic
3.5
7.2
24
70
R06AE07
ATC
cetirizine; oral
1.5
7.2
342
2641
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
7.1
383
3025
XCH00
NOMESCO Finland
Eye pressure measurement
2.5
7.1
44
182
CBA10
NOMESCO Finland
Biopsy of eyelid
6.1
7.1
18
30
F13
ICPC
Eye sensation abnormal
3.1
7.1
29
96
S01GX06
ATC
emedastine; ophthalmic
10.1
7.0
13
13
J05AB01
ATC
aciclovir; systemic
1.6
7.0
185
1255
J01FA10
ATC
azithromycin; systemic
1.5
7.0
462
3795
S29
ICPC
Skin symptom/complaint other
1.7
7.0
153
991
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.7
6.9
121
736
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.9
6.9
84
456
N02BE01
ATC
paracetamol; systemic, rectal
1.7
6.9
762
6961
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
6.9
246
1786
R21
ICPC
Throat symptom/complaint
1.7
6.9
153
995
F45.8
ICD-10 Finland
Other somatoform disorders
2.2
6.8
55
257
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
2.4
6.7
45
193
L82
ICD-10 Finland
Seborrhoeic keratosis
1.6
6.7
156
1025
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.1
6.7
59
285
A02BC05
ATC
esomeprazole; systemic
1.5
6.7
337
2621
ZXA10
NOMESCO Finland
Bilateral
1.6
6.7
157
1034
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
6.7
422
3426
N02AX02
ATC
tramadol; systemic, rectal
1.5
6.6
351
2754
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
6.6
109
653
J02AC01
ATC
fluconazole; systemic
1.5
6.5
320
2474
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.9
6.5
87
489
D06
ICPC
Abdominal pain localized other
2.0
6.4
69
359
H10
ICD-10 Finland
Conjunctivitis
2.2
6.4
54
256
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.0
6.4
73
388
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
6.4
297
2268
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
6.4
358
2837
L04AX01
ATC
azathioprine; systemic
2.5
6.3
37
149
3401
FHL
Removal of local modification or taking a specimen in the operating room
+∞
6.3
6
*
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
6.2
240
1765
Z01.2
ICD-10 Finland
Dental examination
1.4
6.2
352
2789
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
7.7
6.1
13
17
M01AH01
ATC
celecoxib; oral
1.6
6.1
153
1022
ZA1.0
ICD-10 Finland
Shoulder region
3.1
6.1
24
78
M03BC01
ATC
orphenadrine (citrate); systemic
1.5
6.1
184
1285
H26.2
ICD-10 Finland
Complicated cataract
5.2
6.0
17
33
D07AC13
ATC
mometasone; topical
1.5
6.0
230
1687
M48.0
ICD-10 Finland
Spinal stenosis
1.7
6.0
109
670
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
666
5700
1.71
10.10
8.7
7.5
74.54
79.17
u/l
2.86
627
5343
755
6798
1.81
8.32
6.2
5.8
39.73
39.99
mmol/mol
0.33
685
6306
627
5393
1.57
8.19
5.2
4.1
11.03
12.48
mm/h
2.50
586
4970
451
3651
1.49
7.58
7.3
6.6
1.22
1.22
mmol/l
0.67
378
3107
781
7153
1.85
7.47
5.1
4.6
5.91
5.96
mmol/l
0.46
708
6491
788
7245
1.88
7.33
17.7
14.1
20.34
23.47
mg/l
1.94
644
5689
799
7396
1.92
7.02
5.5
5.0
2.77
2.77
mmol/l
0.02
724
6799
260
1915
1.51
6.79
5.6
4.0
0.00
0.01
estimate
0.88
89
634
743
6761
1.66
6.61
5.6
4.7
1.87
1.91
mu/l
0.39
670
6148
420
3411
1.44
6.61
14.8
14.7
1.21
1.25
inr
0.40
136
969
640
5639
1.50
6.50
4.8
4.0
14.76
14.83
pmol/l
0.31
573
5102
437
3601
1.43
6.21
4.8
3.7
0.00
0.01
estimate
0.80
88
635
433
3564
1.43
6.18
5.9
5.0
0.00
0.00
estimate
0.50
89
653
500
4224
1.43
6.17
9.9
9.1
4.02
4.06
e9/l
0.16
450
3694
208
1491
1.52
6.09
3.1
2.6
4.63
6.16
e6/l
1.22
195
1355
98
585
1.76
6.00
3.0
2.6
61.12
64.70
ml/min/173m2
0.40
41
244
392
3182
1.42
5.99
6.1
4.7
34.82
35.47
g/l
1.44
360
2978
782
7260
1.73
5.85
4.9
4.5
4.72
4.70
mmol/l
0.22
709
6717
806
7552
1.85
5.78
20.2
16.3
139.84
139.70
mmol/l
0.92
790
7338
502
4272
1.41
5.77
5.2
4.7
6.64
6.70
mmol/l
0.25
474
4000
28
103
2.78
5.74
2.6
3.7
—
676.09
—
0
11
807
7572
1.85
5.65
20.4
16.4
3.96
3.97
mmol/l
0.26
789
7347
429
3563
1.40
5.63
4.8
3.7
0.00
0.00
estimate
0.74
92
708
777
7216
1.69
5.61
4.8
4.4
1.52
1.49
mmol/l
0.85
702
6624
276
2133
1.43
5.43
3.1
3.0
1655.38
1212.48
ng/l
0.77
238
1804
403
3326
1.39
5.42
6.9
5.9
1.22
1.21
mmol/l
0.22
368
3030
16
43
3.77
5.38
1.9
2.2
—
—
—
0
0
753
6967
1.58
5.19
4.4
4.0
1.30
1.29
mmol/l
0.14
679
6354
317
2541
1.39
4.96
2.9
3.4
2.35
2.36
mmol/l
0.68
276
2246
749
6952
1.54
4.75
17.0
13.1
77.61
79.77
ml/min/173m2
1.96
629
5709
371
3077
1.36
4.61
3.1
2.7
120.64
129.94
ug/l
0.33
341
2817
335
2737
1.36
4.57
5.2
3.9
—
—
—
0
0
212
1607
1.42
4.53
1.3
1.3
1.94
2.10
u/ml
0.04
62
427
544
4792
1.36
4.51
5.7
4.4
38.00
3223.81
e6/l
—
8
74
817
7765
1.79
4.46
13.1
10.4
24.73
25.52
u/l
0.94
791
7475
171
1252
1.45
4.40
1.3
1.3
195.72
32.40
iu/ml
0.46
42
421
91
585
1.62
4.25
4.5
3.5
93.59
82.32
ng/l
0.51
77
517
144
1027
1.48
4.23
2.4
2.3
2.34
2.33
g/l
0.07
137
954
30
134
2.28
4.19
8.6
7.2
134.00
319.96
iu/ml
—
5
26
840
8072
2.02
4.14
26.2
20.8
4.46
4.47
e12/l
0.07
812
7835
241
1893
1.38
4.14
2.7
2.5
6037.63
6588.69
umol/l
0.07
214
1653
28
122
2.34
4.14
1.7
1.3
88.37
106.93
u/ml
—
9
19
95
623
1.59
4.10
3.4
4.0
1.24
1.23
mmol/l
0.94
84
546
840
8075
2.01
4.09
26.3
20.9
134.46
134.52
g/l
0.04
826
7944
839
8067
1.97
4.00
26.1
20.9
40.29
39.90
%
1.41
793
7526
839
8067
1.97
4.00
26.2
20.8
254.58
251.82
e9/l
0.60
816
7852
286
2328
1.34
3.87
2.9
2.5
52.95
95.94
u/l
0.67
264
2148
489
4294
1.31
3.85
3.0
2.8
—
—
—
0
0
365
3080
1.32
3.83
2.7
2.3
79.48
78.24
nmol/l
0.36
334
2744
337
2819
1.32
3.74
4.1
3.5
856.60
48.99
ng/l
0.48
232
1986
185
1413
1.39
3.73
1.5
1.4
2.76
2.45
g/l
0.32
120
841
228
1803
1.36
3.71
2.6
2.2
3.12
3.01
mg/l
0.23
199
1529
13
34
3.86
3.70
1.2
1.4
171.69
156.17
mmol/24h
0.31
13
34
399
3426
1.30
3.63
7.2
5.8
57.29
57.09
%
0.12
372
3208
404
3475
1.30
3.63
7.7
6.1
27.69
27.86
%
0.12
375
3259
68
426
1.65
3.55
1.4
1.2
353.53
192.45
u/ml
0.34
62
391
201
1574
1.36
3.46
1.7
1.7
0.85
1.15
mg/l
2.45
160
1218
266
2179
1.32
3.37
3.8
3.2
20.31
85.07
e6/l
1.42
216
1682
678
6289
1.35
3.33
19.9
17.0
15.03
15.05
%
0.04
665
6180
246
1996
1.32
3.33
3.6
3.1
0.23
0.44
e6/l
2.52
206
1516
148
1114
1.40
3.24
1.5
1.4
—
—
—
0
0
149
1135
1.38
3.04
2.5
2.3
13.62
13.01
umol/l
0.49
141
1061
394
3432
1.27
3.03
2.6
2.6
—
—
—
0
0
266
2214
1.29
2.93
2.3
2.1
158.21
240.92
u/l
1.30
248
2079
113
829
1.42
2.87
2.7
2.5
1.69
1.81
%
0.77
102
741
196
1571
1.32
2.85
5.8
4.0
1.01
1.02
kg/l
1.20
25
221
129
972
1.38
2.81
2.5
2.4
23.45
22.88
%
0.15
110
830
19
84
2.29
2.78
1.3
1.4
32.06
29.60
u/l
0.11
13
71
124
931
1.39
2.76
8.0
6.7
—
—
—
0
0
174
1384
1.32
2.67
3.0
3.0
2.46
2.46
mmol/l
0.09
160
1220
11
35
3.17
2.65
2.9
3.4
901.55
720.14
u/ml
0.14
11
35
126
956
1.37
2.63
6.9
5.1
1.05
1.03
mmol/l
0.35
120
882
153
1197
1.34
2.63
3.6
3.3
0.80
0.81
mmol/l
0.39
143
1127
26
135
1.95
2.57
4.6
3.7
55.69
57.79
%
0.38
26
135
149
1165
1.34
2.57
1.4
1.4
—
—
—
0
0
115
866
1.38
2.52
2.1
2.2
157.53
122.85
ug/g
0.46
87
690
25
129
1.97
2.52
4.4
3.4
3.80
4.33
e9/l
0.84
25
129
19
89
2.16
2.46
1.7
1.3
—
—
—
0
0
39
234
1.70
2.46
2.9
2.0
—
—
—
0
0
272
2316
1.25
2.42
3.4
3.1
6.84
7.17
mmol/l
0.73
224
1950
101
750
1.39
2.41
3.5
3.3
—
—
—
0
0
5
8
6.28
2.37
3.8
5.0
—
—
—
0
0
49
316
1.58
2.35
4.5
3.6
48.83
47.40
%
0.16
49
310
49
316
1.58
2.35
2.9
2.2
42.37
39.72
u/l
0.49
43
277
62
423
1.50
2.32
3.2
3.2
4.37
4.55
pmol/l
0.93
54
369
90
660
1.41
2.32
5.1
3.4
2.17
2.04
mmol/l
0.13
77
542
433
3890
1.22
2.31
6.8
6.2
10.22
11.10
umol/l
1.74
410
3690
35
208
1.71
2.30
2.1
1.7
—
—
—
0
0
345
3035
1.23
2.25
2.1
2.0
93.01
95.62
pmol/l
0.50
173
1534
149
1188
1.31
2.24
1.3
1.3
1.79
11.30
u/ml
5.02
49
453
90
666
1.39
2.21
5.1
3.4
5.81
5.80
kpa
0.00
90
645
8
24
3.35
2.18
1.0
1.1
1574.88
1827.71
miu/ml
—
8
24
7
19
3.70
2.15
1.0
1.1
3.81
3.83
umol/l
—
7
19
44
284
1.58
2.12
1.2
1.3
33.51
31.38
iu/l
0.16
39
240
7
20
3.52
2.06
2.7
2.0
—
—
—
0
0
105
810
1.34
2.00
1.9
1.8
—
—
—
0
0
268
2321
1.22
1.99
3.9
3.8
7.18
7.67
mg/mmol
0.09
168
1440
516
4758
1.21
1.99
3.6
3.1
47.70
48.95
u/l
0.10
469
4416
27
156
1.75
1.98
1.1
1.2
—
—
—
0
0
253
2183
1.22
1.95
3.4
3.2
366.14
248.10
mg/l
0.14
153
1389
13
58
2.26
1.91
2.2
2.5
—
—
—
0
0
34
212
1.63
1.91
1.2
1.2
—
—
—
0
0
7
22
3.20
1.88
1.3
1.1
—
—
—
0
0
164
1355
1.26
1.87
1.8
1.7
1298.67
1188.81
nmol/l
0.75
128
1016
35
225
1.58
1.76
1.7
2.9
—
—
—
0
0
7
24
2.93
1.72
2.1
1.2
—
—
—
0
0
23
133
1.75
1.71
1.3
1.2
245.65
266.53
u/ml
0.18
17
74
17
90
1.91
1.66
1.2
1.2
—
0.50
nmol/l
—
0
6
7
25
2.81
1.65
3.1
1.9
17.00
14.47
pmol/l
—
7
19
73
553
1.35
1.60
3.9
2.9
4.20
4.48
kpa
1.25
73
530
6
20
3.01
1.58
1.0
1.2
—
—
—
0
0
7
26
2.71
1.58
1.3
1.3
—
—
—
0
0
89
698
1.31
1.55
3.3
2.3
0.21
0.21
g/l
0.11
83
653
102
815
1.28
1.55
2.0
1.8
—
—
—
0
0
14
71
1.99
1.54
1.2
1.2
—
—
—
0
0
5
15
3.35
1.52
1.8
1.1
81.40
101.27
%
—
5
15
49
351
1.42
1.51
1.1
1.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
6
21
2.87
1.50
1.5
1.7
120.17
118.10
%
—
6
21
15
79
1.91
1.50
1.0
1.2
—
—
—
0
0
23
142
1.64
1.39
1.3
1.2
—
—
—
0
0
28
183
1.55
1.36
1.3
1.2
—
3.32
—
0
15
26
168
1.56
1.33
1.7
2.2
130.10
128.20
g/l
0.13
20
128
6
24
2.51
1.30
3.3
5.1
—
—
—
0
0
13
69
1.90
1.29
1.8
1.7
—
—
—
0
0
5
18
2.79
1.28
2.4
3.6
—
—
—
0
0
5
18
2.79
1.28
2.4
3.6
—
—
—
0
0
30
203
1.49
1.26
1.8
1.9
92.23
90.75
%
0.14
30
198
10
49
2.05
1.22
1.2
1.4
—
275.00
—
0
6
77
615
1.28
1.21
2.6
2.3
13.60
7.13
ug/l
0.53
69
535
28
189
1.50
1.20
2.0
1.5
335.68
294.16
mu/l
0.44
28
167
43
317
1.37
1.17
1.6
1.8
1.63
1.52
g/l
0.32
38
285
10
50
2.01
1.16
2.1
1.8
24.10
20.72
nmol/l
—
10
45
10
50
2.01
1.16
1.8
1.3
—
—
—
0
0
5
20
2.51
1.15
3.4
1.6
177.80
76.45
nmol/24h
—
5
20
10
51
1.97
1.11
1.8
1.3
—
—
—
0
0
204
1813
1.16
1.10
5.3
3.7
91.90
91.19
%
0.13
198
1769
12
66
1.83
1.09
1.0
1.1
—
—
—
0
0
8
41
1.96
1.09
2.0
1.5
71.75
82.17
umol/l
—
8
41
141
1218
1.19
1.07
3.1
2.7
1.16
1.12
e6/l
0.03
87
683
179
1578
1.17
1.07
4.7
4.2
23.27
20.93
%
1.06
90
760
135
1163
1.19
1.06
2.1
1.9
—
—
—
0
0
12
67
1.80
1.05
1.5
1.4
637702.14
164644.87
e6/l
—
7
45
101
848
1.22
1.04
3.5
2.7
9.67
8.17
umol/l
0.24
86
743
17
106
1.62
1.03
1.9
2.0
33.29
32.53
pg
0.39
17
106
7
34
2.07
1.03
1.3
1.6
1.31
1.16
nmol/l
—
7
28
30
213
1.42
1.03
1.9
1.6
0.01
0.09
iu/ml
—
8
39
39
292
1.35
0.99
1.9
2.0
2.11
2.44
ug/l
0.08
34
261
29
207
1.41
0.97
1.4
1.6
—
—
—
0
0
29
208
1.41
0.95
1.1
1.1
—
—
—
0
0
55
438
1.27
0.92
1.7
1.6
—
—
—
0
0
98
832
1.20
0.92
5.5
7.9
5.03
5.14
kpa
0.82
90
801
156
1378
1.16
0.92
3.9
3.7
327.88
410.53
ng/l
0.20
112
1088
29
210
1.39
0.91
1.1
1.1
—
—
—
0
0
18
118
1.54
0.91
4.1
3.4
0.64
1.05
%
0.74
18
107
97
825
1.20
0.90
5.6
8.0
0.64
1.29
mmol/l
0.95
72
669
22
153
1.45
0.86
1.5
1.4
—
—
—
0
0
8
44
1.83
0.86
1.0
1.0
—
—
—
0
0
195
1761
1.14
0.85
2.4
2.3
—
—
—
0
0
13
80
1.63
0.85
2.8
1.9
—
—
—
0
0
217
1975
1.13
0.84
5.2
5.0
2.28
2.54
ug/l
0.39
195
1754
97
833
1.18
0.82
5.6
7.9
13.34
12.20
kpa
1.03
89
804
174
1567
1.14
0.79
1.7
1.7
39286155.21
39413107.39
pmol/l
0.00
140
1294
44
349
1.27
0.79
6.3
3.7
23.65
24.20
mmol/l
0.46
44
339
95
821
1.18
0.76
3.9
4.2
9.62
31.20
ug/l
1.18
75
680
68
570
1.21
0.76
1.8
1.9
—
—
—
0
0
5
24
2.09
0.74
1.8
1.6
—
—
—
0
0
5
24
2.09
0.74
2.6
1.2
—
—
—
0
0
14
92
1.53
0.72
1.2
1.1
0.33
2.18
u/ml
—
9
46
129
1147
1.15
0.72
3.2
3.0
0.81
0.78
ug/l
0.08
95
758
192
1752
1.12
0.72
1.6
1.6
22.96
20.83
nmol/l
0.69
163
1476
19
134
1.43
0.71
2.4
1.6
—
—
—
0
0
51
419
1.23
0.70
2.2
2.3
12.68
12.77
nmol/l
0.02
46
373
24
178
1.36
0.69
2.0
1.7
9262.94
13123.05
e6/l
0.34
17
128
11
69
1.60
0.68
4.9
3.3
63.59
53.70
%
1.27
11
62
7
42
1.67
0.68
3.9
1.8
—
—
—
0
0
9
59
1.53
0.68
1.0
1.1
—
—
—
0
0
9
59
1.53
0.68
1.0
1.1
—
—
—
0
0
29
223
1.31
0.67
1.9
3.2
4.59
2.04
ratio
—
5
19
7
43
1.63
0.67
3.9
1.8
—
—
—
0
0
5
29
1.73
0.64
1.2
1.5
—
—
—
0
0
31
243
1.29
0.63
1.5
1.5
—
—
—
0
0
56
471
1.20
0.63
3.6
3.4
1.61
1.87
mmol/l
0.20
41
353
15
104
1.45
0.62
2.5
1.7
—
—
—
0
0
8
49
1.64
0.62
1.1
1.1
—
—
—
0
0
88
772
1.16
0.61
1.9
1.7
1.49
1.49
%
0.00
76
673
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
28
218
1.29
0.60
2.4
2.5
0.29
0.35
u/ml
0.37
11
125
8
52
1.54
0.59
3.5
1.7
—
—
—
0
0
20
149
1.35
0.58
2.0
2.0
8104.73
1690.06
u/l
—
6
63
15
106
1.42
0.58
2.7
1.7
—
—
—
0
0
12
81
1.49
0.57
5.1
3.6
—
—
—
0
0
51
432
1.19
0.55
1.9
1.4
—
—
—
0
0
9
60
1.51
0.54
1.0
1.1
—
—
—
0
0
9
60
1.51
0.54
1.0
1.1
—
—
—
0
0
9
60
1.51
0.54
1.0
1.1
—
—
—
0
0
12
83
1.45
0.52
2.2
3.3
69.77
53.29
u/ml
0.15
12
83
59
510
1.17
0.51
1.9
1.8
—
—
—
0
0
52
605
0.85
0.51
1.7
1.7
—
—
—
0
0
21
162
1.30
0.50
2.3
2.6
16.21
15.99
%
0.08
12
87
7
107
0.65
0.49
1.1
1.1
—
15.25
—
0
6
17
128
1.33
0.48
1.2
1.2
—
—
—
0
0
60
524
1.16
0.47
1.7
1.6
—
—
—
0
0
23
182
1.27
0.47
1.1
1.3
685.30
495.17
mg/l
0.59
23
171
5
82
0.61
0.46
1.2
1.5
—
—
—
0
0
74
658
1.14
0.45
2.7
2.3
31.72
35.90
u/l
0.71
69
541
16
121
1.33
0.44
1.2
1.9
156.13
218.50
pmol/l
1.62
16
112
5
31
1.62
0.43
1.4
1.4
—
—
—
0
0
6
91
0.66
0.42
1.0
1.1
—
—
—
0
0
24
194
1.24
0.42
1.3
1.3
182.31
235.23
miu/ml
0.28
13
86
8
57
1.41
0.42
3.5
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
27.02
—
0
15
0
15
0.00
0.41
0.0
1.1
—
28.63
—
0
10
5
34
1.47
0.40
1.8
2.7
30834.20
38247.21
ug/l
—
5
34
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
5
36
1.39
0.38
4.4
4.2
—
118.33
—
0
6
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
5
77
0.65
0.36
1.2
1.9
—
—
—
0
0
6
42
1.43
0.35
1.3
1.1
—
—
—
0
0
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
6
43
1.40
0.35
1.3
1.2
—
—
—
0
0
6
44
1.37
0.34
1.0
1.5
—
—
—
0
0
43
378
1.14
0.33
4.0
2.7
0.22
0.22
e6/l
0.03
43
366
13
166
0.78
0.33
1.5
1.5
—
—
—
0
0
18
146
1.24
0.32
1.4
1.4
—
—
—
0
0
18
146
1.24
0.32
1.4
1.4
—
—
—
0
0
18
218
0.82
0.30
2.7
1.6
—
—
—
0
0
11
84
1.31
0.30
1.3
1.7
54.67
60.34
%
—
6
58
13
102
1.28
0.30
2.7
1.7
—
—
—
0
0
208
1988
1.06
0.30
1.8
1.7
1.39
1.37
mmol/l
0.17
169
1660
7
56
1.25
0.29
3.6
1.6
0.92
1.02
g/l
—
7
56
8
63
1.27
0.28
1.3
1.2
—
—
—
0
0
13
161
0.80
0.27
1.0
1.6
0.64
0.86
nmol/l
—
8
134
19
159
1.20
0.27
1.6
1.8
54.42
40.08
nmol/l
0.78
19
153
53
482
1.11
0.26
1.1
1.2
88.64
142.22
iu/ml
0.90
18
191
244
2356
1.05
0.25
4.3
3.2
34.83
31.61
u/l
0.38
237
2244
121
1151
1.06
0.21
3.2
2.9
2.36
2.53
e6/l
0.08
67
624
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
7.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
8
104
0.77
0.21
1.0
1.4
—
—
—
0
0
8
104
0.77
0.21
1.1
1.1
—
—
—
0
0
5
43
1.16
0.21
3.0
3.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
39
355
1.10
0.20
1.3
1.3
—
—
—
0
0
20
174
1.15
0.20
1.4
1.7
—
—
—
0
0
6
50
1.20
0.19
1.0
1.9
—
—
—
0
0
15
128
1.17
0.18
2.4
1.9
—
—
—
0
0
12
100
1.20
0.18
1.0
1.1
—
—
—
0
0
19
216
0.88
0.17
1.4
1.7
—
—
—
0
0
5
70
0.71
0.16
1.4
1.1
—
—
—
0
0
8
68
1.18
0.16
1.3
1.3
—
—
—
0
0
8
73
1.10
0.15
1.8
2.2
—
—
—
0
0
6
77
0.78
0.15
1.0
1.1
—
—
—
0
0
15
170
0.88
0.13
1.1
1.1
—
—
—
0
0
20
180
1.11
0.13
2.9
2.4
102.71
88.91
ug/min
0.05
12
112
9
106
0.85
0.13
1.0
1.4
—
—
—
0
0
9
106
0.85
0.13
1.0
1.4
—
—
—
0
0
21
190
1.11
0.13
1.2
1.4
71.90
260.71
pmol/l
1.42
21
185
27
292
0.92
0.12
2.5
1.8
—
—
—
0
0
5
44
1.14
0.10
1.2
1.4
1.50
2.73
ug/l
—
5
35
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
44
1.14
0.10
1.0
1.2
—
—
—
0
0
16
176
0.91
0.09
1.6
1.2
—
—
—
0
0
19
174
1.09
0.09
2.4
1.7
—
—
—
0
0
11
97
1.14
0.09
2.2
2.1
90.38
90.08
%
0.08
11
97
30
282
1.07
0.09
3.2
1.8
—
—
—
0
0
13
144
0.90
0.08
3.1
1.5
—
—
—
0
0
10
113
0.88
0.08
1.5
1.6
—
—
—
0
0
5
64
0.78
0.08
1.4
1.6
—
—
—
0
0
5
64
0.78
0.08
1.8
2.1
—
—
—
0
0
5
64
0.78
0.08
1.4
1.6
—
—
—
0
0
5
64
0.78
0.08
1.4
1.6
—
—
—
0
0
13
117
1.11
0.08
2.8
1.6
—
—
—
0
0
7
64
1.09
0.08
1.0
1.0
—
—
—
0
0
7
67
1.05
0.08
1.0
1.1
—
—
—
0
0
8
75
1.07
0.07
1.6
1.6
—
—
—
0
0
7
81
0.86
0.07
1.4
1.4
—
—
—
0
0
7
82
0.85
0.07
1.0
1.1
—
—
—
0
0
7
85
0.82
0.07
1.1
1.8
—
—
—
0
0
17
157
1.08
0.07
5.4
3.6
18.37
25.75
mg/l
—
10
97
9
87
1.03
0.07
1.8
1.6
—
—
—
0
0
9
87
1.03
0.07
1.8
1.6
—
—
—
0
0
23
216
1.07
0.07
3.5
1.7
0.00
0.02
g/l
0.50
23
203
17
183
0.93
0.06
2.0
1.3
—
—
—
0
0
9
104
0.86
0.06
1.0
1.4
—
—
—
0
0
9
104
0.86
0.06
1.0
1.4
—
—
—
0
0
9
105
0.86
0.06
1.0
1.4
—
—
—
0
0
23
217
1.06
0.06
1.6
1.5
274.41
291.12
ug/g
0.14
14
127
18
168
1.07
0.06
1.1
1.4
—
—
—
0
0
28
267
1.05
0.05
2.4
1.7
—
—
—
0
0
11
120
0.92
0.05
1.6
1.6
—
—
—
0
0
11
120
0.92
0.05
1.6
1.6
—
—
—
0
0
94
955
0.98
0.04
4.7
4.5
30.43
32.53
%
1.12
65
651
24
250
0.96
0.03
1.2
1.4
—
—
—
0
0
18
171
1.05
0.03
2.5
1.8
—
—
—
0
0
22
211
1.04
0.03
1.0
1.2
—
—
—
0
0
18
173
1.04
0.01
2.8
1.7
3.18
4.17
iu/l
—
8
55
19
197
0.96
0.01
1.8
1.4
—
—
—
0
0
27
263
1.03
0.01
2.6
1.9
5.65
3.30
mg/l
0.35
21
205
11
106
1.04
0.00
1.0
1.2
1.17
1.83
u/ml
—
6
30
11
114
0.96
0.00
1.1
1.1
—
—
—
0
0
12
118
1.02
0.00
5.5
2.8
54.40
61.64
%
0.54
12
118
20
198
1.01
0.00
2.6
1.7
0.00
0.00
g/l
-0.00
20
187
27
268
1.01
0.00
2.1
1.7
—
—
—
0
0
11
107
1.03
0.00
1.7
1.5
—
—
—
0
0
15
151
0.99
0.00
2.3
2.9
0.88
0.86
nmol/l
—
10
118
9
96
0.94
-0.00
2.1
2.7
104.11
105.36
mmol/l
—
9
96
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
5
59
0.85
-0.00
1.4
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
85.33
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.4
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.4
—
—
—
0
0
20
200
1.00
-0.00
2.6
1.7
0.00
0.00
g/l
-0.00
20
188
9
99
0.91
-0.00
1.4
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.4
—
0.75
—
0
8
9
98
0.92
-0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
-0.00
1.3
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUVASC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUVASC | 0.92 [0.81, 1.05] | 0.219 |
| Birth year | 0.994 [0.99, 1.0] | 0.16 |
During the follow-up period (1.1.1998 — 31.12.2019), 359 out of 2876 females with H7_CONJUVASC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUVASC | 0.928 [0.81, 1.06] | 0.266 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 388 out of 2074 males with H7_CONJUVASC died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUVASC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.187% |
| 5 | 0.519% | 1.012% |
| 10 | 1.248% | 2.506% |
| 15 | 2.497% | 4.787% |
| 20 | 4.41% | 8.114% |
Relationships between endpoints
↥Index endpoint: H7_CONJUVASC – Other conjunctival vascular disorders and cysts
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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