No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
831 |
4. Check minimum number of eventsNone |
831 |
5. Include endpointsNone |
831 |
6. Filter based on genotype QC (FinnGen only) |
831 |
Control definitions (FinnGen only)
- Control exclude
- H7_CONJUNCTIVA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H11
- Name in latin
- Aliae morbositates vasculares et cystae conjunctivae
Similar endpoints
↥List of similar endpoints to
Other conjunctival vascular disorders and cysts
based on the number of shared cases.
Similar with more cases:
- Other disorders of conjunctiva
- Disorders of conjunctiva
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5855 | 3365 | 2462 |
| Only index persons | 5436 | 3191 | 2245 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.07 |
| Only index persons | 0.10 | 0.12 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 55.86 | 55.85 | 55.92 |
| Only index persons | 55.47 | 55.40 | 55.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 831 | 524 | 307 |
| Unadjusted period prevalence (%) | 0.16 | 0.18 | 0.14 |
| Median age at first event (years) | 56.29 | 54.49 | 59.37 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 738
- Matched controls
- 7380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
4503599627370496.0
323.0
708
*
CFC00
NOMESCO Finland
Excision of lesion of conjunctiva
217.2
109.8
111
6
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.0
40.0
330
1575
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
34.6
380
2102
CBB30
NOMESCO Finland
Excision of lesion of eyelid
8.4
28.8
65
84
S01GX01
ATC
cromoglicic acid; ophthalmic
3.4
26.8
148
512
CFA20
NOMESCO Finland
Biopsy of conjunctiva
96.9
25.8
28
*
H04.10
ICD-10 Finland
Dry eye syndrome
3.7
22.5
106
321
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
25.4
19.6
27
11
37820
ICD-8 Finland
Other diseases of eye, Cysta conjunctivae
+∞
15.7
15
*
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
4.7
14.9
51
115
3727A
ICD-9 Finland
Disorders of conjunctiva, Conjunctival vascular disorders and cysts
+∞
14.6
14
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
13.3
137
671
H11.0
ICD-10 Finland
Pterygium
32.6
12.6
16
5
S01GX02
ATC
levocabastine; ophthalmic
4.3
12.1
45
111
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
8.9
12.1
25
29
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.5
11.3
95
415
F29
ICPC
Eye symptom/complaint other
2.7
11.0
76
300
H00.1
ICD-10 Finland
Chalazion
4.1
10.6
40
101
H10.4
ICD-10 Finland
Chronic conjunctivitis
111.5
10.4
11
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.9
10.0
40
106
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.5
9.8
80
345
M01AE02
ATC
naproxen; oral, rectal
1.6
9.5
405
3155
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
+∞
9.4
9
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.4
9.3
80
354
H15.1
ICD-10 Finland
Episcleritis
7.4
9.3
21
29
M03BX02
ATC
tizanidine; oral
1.6
9.2
443
3546
J05AB01
ATC
aciclovir; systemic
1.8
8.6
148
882
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.2
8.6
31
76
S01GX09
ATC
olopatadine; ophthalmic
7.5
8.5
19
26
XCK00
NOMESCO Finland
Perimetry
2.8
8.3
53
201
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.6
8.1
365
2836
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
8.0
130
755
J01DB01
ATC
cefalexin; oral
1.7
7.9
583
5102
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.1
7.9
90
456
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
3.2
7.9
40
131
S01GX08
ATC
ketotifen; ophthalmic
4.7
7.6
24
52
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
7.4
120
698
H11.8
ICD-10 Finland
Other specified disorders of conjunctiva
15.9
7.2
11
7
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
7.2
309
2355
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
7.1
484
4080
127
Kela drug reimbursment
Transplant complication
5.4
7.1
20
38
M25.5
ICD-10 Finland
Pain in joint
1.6
7.0
202
1393
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.2
6.8
34
111
H11.9
ICD-10 Finland
Disorder of conjunctiva, unspecified
22.7
6.7
9
*
H26.2
ICD-10 Finland
Complicated cataract
6.5
6.7
16
25
H20.1
ICD-10 Finland
Chronic iridocyclitis
6.5
6.7
16
25
H01.0
ICD-10 Finland
Blepharitis
2.8
6.6
42
158
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
6.6
249
1834
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
6.5
341
2692
CBA10
NOMESCO Finland
Biopsy of eyelid
7.5
6.4
14
19
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
6.4
103
596
D07AC13
ATC
mometasone; topical
1.6
6.4
192
1335
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
11.1
6.3
11
10
S18
ICPC
Laceration/cut
1.5
6.3
289
2215
H57.1
ICD-10 Finland
Ocular pain
3.2
6.3
30
95
H53.1
ICD-10 Finland
Subjective visual disturbances
2.5
6.3
48
203
J01FA10
ATC
azithromycin; systemic
1.5
6.2
385
3138
J02AB02
ATC
ketoconazole; oral
3.7
6.2
25
69
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
6.1
375
3048
L04AD01
ATC
ciclosporin; systemic
4.4
6.1
20
46
Mortality – FinRegistry
↥Association
Association between endpoint H7_CONJUVASC and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUVASC | 0.92 [0.81, 1.05] | 0.219 |
| Birth year | 0.994 [0.99, 1.0] | 0.16 |
During the follow-up period (1.1.1998 — 31.12.2019), 359 out of 2876 females with H7_CONJUVASC died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CONJUVASC | 0.928 [0.81, 1.06] | 0.266 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 388 out of 2074 males with H7_CONJUVASC died.
Mortality risk
Mortality risk for people of age
years, who have H7_CONJUVASC.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.187% |
| 5 | 0.519% | 1.012% |
| 10 | 1.248% | 2.506% |
| 15 | 2.497% | 4.787% |
| 20 | 4.41% | 8.114% |
Relationships between endpoints
↥Index endpoint: H7_CONJUVASC – Other conjunctival vascular disorders and cysts
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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