hypersensitivity vasculitis: Disorder characterized by a vasculitic syndrome associated with exposure to an antigen such as a drug, infectious agent, or other foreign or endogenous substance. Its pathophysiology includes immune complex deposition and a wide range of skin lesions. Hypersensitivity or allergy is present in some but not all cases.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
830 |
4. Check minimum number of eventsNone |
830 |
5. Include endpointsNone |
830 |
6. Filter based on genotype QC (FinnGen only) |
830 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other and unspecified vasculitis limited to skin
based on the number of shared cases.
Similar with more cases:
- Vasculitis limited to skin, not elsewhere classified
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5748 | 3379 | 2331 |
| Only index persons | 5105 | 3007 | 2098 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.07 |
| Only index persons | 0.10 | 0.11 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 64.72 | 66.92 | 61.51 |
| Only index persons | 63.26 | 65.05 | 60.70 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 830 | 475 | 355 |
| Unadjusted period prevalence (%) | 0.16 | 0.16 | 0.16 |
| Median age at first event (years) | 61.52 | 60.40 | 63.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 754
- Matched controls
- 7538
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
13083.4
323.0
554
*
L95.8
ICD-10 Finland
Other vasculitis limited to skin
+∞
323.0
322
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
24.5
257.7
398
329
H02AB06
ATC
prednisolone; systemic
8.8
145.8
617
2554
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
83.8
139.2
154
23
D69.0
ICD-10 Finland
Allergic purpura
81.6
116.0
129
19
S97
ICPC
Chronic ulcer skin
17.2
99.6
164
120
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
99.9
88.4
96
11
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
13.7
77.8
140
123
J04BA02
ATC
dapsone; oral
207.8
73.6
75
*
L04AX01
ATC
azathioprine; systemic
14.1
71.1
126
106
A46
ICD-10 Finland
Erysipelas
5.4
65.1
226
551
L30.9
ICD-10 Finland
Dermatitis, unspecified
4.8
64.4
259
741
D07AC01
ATC
betamethasone; topical
3.8
64.2
394
1669
TQW80
NOMESCO Finland
Local dermatologic skincare
16.7
62.3
102
70
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.7
60.0
391
1709
SPAT1148
SPAT
Treatment of chronic ulcer or burn
5.1
59.3
217
554
J01FF01
ATC
clindamycin; systemic
3.8
56.1
315
1200
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
18.0
55.5
88
55
L95.0
ICD-10 Finland
Livedoid vasculitis
+∞
52.7
50
*
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
25.6
48.5
68
29
E0000UV
ATC
NA
3.1
45.7
395
1993
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
7.2
45.4
117
188
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
43.2
429
2339
D07AD01
ATC
clobetasol; topical
4.0
43.1
199
616
C03CA01
ATC
furosemide; systemic
3.1
43.1
323
1459
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
15.0
39.1
66
48
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
66.6
38.5
44
7
D07AB08
ATC
desonide; topical
4.6
38.3
147
378
N02AX02
ATC
tramadol; systemic, rectal
2.7
35.7
390
2159
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.2
35.3
148
412
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
33.7
140
386
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.6
33.4
169
553
J01DB01
ATC
cefalexin; oral
3.3
32.6
656
5061
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.8
32.3
115
271
ZZA00
NOMESCO Finland
Split skin graft
9.6
32.1
67
76
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
4.1
31.0
133
376
L50.9
ICD-10 Finland
Urticaria, unspecified
7.9
29.4
69
95
A02BC02
ATC
pantoprazole; systemic
2.5
29.3
543
3820
L04AA06
ATC
mycophenolic acid; systemic
16.1
29.0
47
31
H02AB07
ATC
prednisone; oral
3.3
28.3
160
565
S18
ICPC
Laceration/cut
2.4
27.9
375
2216
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
6.3
26.4
73
127
E000001
ATC
NA
2.7
26.0
207
912
D07AC13
ATC
mometasone; topical
2.5
24.8
258
1317
P01BA02
ATC
hydroxychloroquine; oral
3.8
24.4
110
321
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
24.2
271
1432
J01MA02
ATC
ciprofloxacin; systemic
2.3
24.2
343
2031
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
58.0
24.2
28
5
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
39.0
24.1
30
8
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
24.1
23
*
XQ848
NOMESCO Finland
Dermatological photography
8.8
24.0
52
63
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.2
23.5
94
246
M04AA01
ATC
allopurinol; systemic
3.1
23.5
145
539
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.5
23.5
228
1113
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.9
23.4
104
300
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
3.4
22.9
122
408
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.7
22.8
106
317
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
41.5
22.8
28
7
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
3.2
22.3
132
474
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.2
22.1
129
460
I50.9
ICD-10 Finland
Heart failure, unspecified
2.9
22.0
150
591
J01MA12
ATC
levofloxacin; systemic
2.6
21.8
181
807
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
8.8
20.9
45
54
I83.2
ICD-10 Finland
Varicose veins of lower extremities with both ulcer and inflammation
79.1
20.8
23
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.9
20.8
138
536
N02AA05
ATC
oxycodone; systemic
2.7
20.5
154
645
L04AA01
ATC
[U] ciclosporin; systemic
13.5
20.4
35
27
L89
ICD-10 Finland
Decubitus ulcer and pressure area
49.5
20.3
24
5
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.0
20.2
84
228
C03DA01
ATC
spironolactone; oral
3.0
20.1
125
463
R50.9
ICD-10 Finland
Fever, unspecified
2.8
19.2
135
542
R60.0
ICD-10 Finland
Localized oedema
2.9
19.1
125
479
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
19.1
97
311
S76
ICPC
Skin infection other
4.8
18.9
65
146
NHQ40
NOMESCO Finland
Amputation of toe
13.9
18.9
32
24
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.9
18.8
63
138
M30.0
ICD-10 Finland
Polyarteritis nodosa
102.6
18.6
20
*
TQW11
NOMESCO Finland
Vacuum treatment of wound
9.5
18.6
38
42
J01CF05
ATC
flucloxacillin; systemic
6.1
18.5
51
89
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
12.3
18.4
33
28
L50.8
ICD-10 Finland
Other urticaria
9.7
18.3
37
40
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.6
18.2
85
255
H02AB09
ATC
hydrocortisone; systemic
7.5
17.8
42
59
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.5
17.7
152
682
N03AX16
ATC
pregabalin; oral
2.3
17.5
200
1035
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.7
17.3
131
547
B01AA03
ATC
warfarin; systemic
2.3
17.2
190
968
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
4.4
17.1
64
157
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
17.1
151
689
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
22.5
16.9
24
11
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
16.7
149
682
E000003
ATC
NA
4.7
16.6
57
128
R06.0
ICD-10 Finland
Dyspnoea
2.1
16.5
219
1210
A41.9
ICD-10 Finland
Sepsis, unspecified
5.3
16.2
50
100
L52
ICD-10 Finland
Erythema nodosum
17.2
16.2
25
15
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
4.0
15.9
65
174
L81.7
ICD-10 Finland
Pigmented purpuric dermatosis
61.4
15.8
18
*
L88
ICD-10 Finland
Pyoderma gangrenosum
+∞
15.7
15
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.7
15.6
71
208
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.2
15.5
196
1057
C07AB07
ATC
bisoprolol; oral
1.9
15.5
379
2636
M13.9
ICD-10 Finland
Arthritis, unspecified
3.3
15.4
82
272
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.6
15.3
71
212
D07AB02
ATC
hydrocortisone butyrate; topical
2.0
15.2
227
1310
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
15.4
15.0
24
16
WZC30
NOMESCO Finland
Teaching
2.5
14.9
125
549
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.8
14.9
50
110
I50.0
ICD-10 Finland
Congestive heart failure
3.1
14.9
84
290
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.1
14.8
202
1121
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
14.7
83
286
UJF32
NOMESCO Finland
Coloscopy
2.0
14.6
213
1217
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
10.3
14.6
28
28
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.2
14.2
54
135
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.2
14.2
79
268
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.1
14.2
80
276
A02BC01
ATC
omeprazole; systemic
2.0
14.0
240
1452
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
54.4
13.9
16
*
M05BA04
ATC
alendronic acid; oral
2.8
13.6
91
351
M79.6
ICD-10 Finland
Pain in limb
1.9
13.6
279
1801
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
8.6
13.6
29
35
205
Kela drug reimbursment
Chronic hypertension
1.9
13.6
237
1441
SPAT1211
SPAT
Application of soft bandage
2.8
13.6
94
370
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
3.8
13.5
58
162
D02AX
ATC
Other emollients and protectives
4.8
13.5
45
99
D09AB01
ATC
zinc bandage without supplements; topical
6.1
13.5
36
61
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
21.6
13.4
19
9
XF600
NOMESCO Finland
Bloodpressure measurement
3.4
13.4
66
207
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
9.9
13.3
26
27
B01AB05
ATC
enoxaparin; parenteral
1.9
13.3
248
1547
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
13.1
124
580
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
13.0
176
970
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
5.2
12.9
40
81
N03AX12
ATC
gabapentin; oral
2.3
12.9
136
668
S29
ICPC
Skin symptom/complaint other
2.2
12.8
154
803
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
6.1
12.7
34
58
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
15.8
12.7
20
13
SPAT1151
SPAT
Treatment of major wounds
8.4
12.6
27
33
R06AE09
ATC
levocetirizine; oral
2.3
12.6
124
592
L01AA01
ATC
cyclophosphamide; systemic
24.8
12.5
17
7
WX213
NOMESCO Finland
Lower leg blockade
13.5
12.5
21
16
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
12.5
71
247
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
4.7
12.2
41
91
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
12.1
439
3357
D03BA02
ATC
collagenase; topical
27.2
12.1
16
6
I50
ICD-10 Finland
Heart failure
4.7
12.0
40
88
L04AD01
ATC
ciclosporin; systemic
6.6
12.0
30
47
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
3.2
11.9
62
203
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.2
11.9
63
209
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.1
11.6
36
74
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
11.5
83
336
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.8
11.5
78
303
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
11.4
368
2698
J01DA01
ATC
[U] cefalexin; systemic
1.7
11.4
459
3588
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
4.4
11.4
41
98
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
11.3
146
784
G47.3
ICD-10 Finland
Sleep apnoea
2.0
11.3
165
931
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
6.6
11.2
28
44
QD9S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in lower extremities, unspecified
25.4
11.2
15
6
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
11.2
341
2454
A28
ICPC
Limited function/disability NOS
2.2
11.0
126
643
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.8
10.9
72
276
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
10.9
98
445
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
5.5
10.8
31
58
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.8
10.8
70
263
S81.9
ICD-10 Finland
Open wound of lower leg, part unspecified
10.8
10.8
20
19
QDE35
NOMESCO Finland
Repair of skin defect in lower limb after surgery or injury
28.5
10.8
14
5
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
10.6
144
788
N18.8
ICD-10 Finland
Other chronic renal failure
4.2
10.6
39
96
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.4
10.6
91
405
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.1
10.6
40
101
QDB10
SPAT
NA
19.1
10.3
15
8
J01FA06
ATC
roxithromycin; oral
1.7
10.3
293
2052
N02BE01
ATC
paracetamol; systemic, rectal
1.9
10.3
637
5581
A10BA02
ATC
metformin; oral
1.8
10.3
211
1338
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
10.3
205
1287
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.6
10.2
46
135
R03BB04
ATC
tiotropium bromide; inhalant
2.4
10.1
86
382
R23.3
ICD-10 Finland
Spontaneous ecchymoses
5.9
10.0
27
47
E000006
ATC
NA
2.8
10.0
66
252
A10AE05
ATC
insulin detemir; parenteral
3.1
10.0
54
182
D69
ICD-10 Finland
Purpura and other haemorrhagic conditions
40.6
10.0
12
*
D02AE01
ATC
carbamide; topical
2.8
9.9
62
230
SPAT1260
SPAT
Consultation of another employee
1.9
9.9
150
855
D07BC01
ATC
betamethasone and antiseptics; topical
2.2
9.9
103
500
S91.0
ICD-10 Finland
Open wound of ankle
12.4
9.9
17
14
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.7
9.9
69
274
I50.1
ICD-10 Finland
Left ventricular failure
3.3
9.8
49
156
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.1
9.8
30
61
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.6
9.8
43
124
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
55.7
9.7
11
*
WX892
NOMESCO Finland
Monitored bed care
2.6
9.6
68
272
L84
ICD-10 Finland
Corns and callosities
4.9
9.6
30
63
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
9.5
205
1314
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.4
9.5
33
77
L30.3
ICD-10 Finland
Infective dermatitis
3.9
9.4
38
102
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
101.2
9.4
10
*
A07EC01
ATC
sulfasalazine; oral, rectal
2.5
9.4
73
308
J01MA14
ATC
moxifloxacin; systemic
2.5
9.4
76
329
S91.3
ICD-10 Finland
Open wound of other parts of foot
5.3
9.3
27
52
C02AC05
ATC
moxonidine; oral
3.2
9.2
48
159
TGC00
NOMESCO Finland
Bronchial lavation
4.5
9.1
31
71
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
9.1
291
2088
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.3
9.1
82
375
QDA10
NOMESCO Finland
Incision of skin of lower limb
15.8
9.1
14
9
R03DC03
ATC
montelukast; oral
2.0
9.0
125
686
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
9.0
136
773
R4110
NOMESCO Finland
Physiotherapy
1.7
9.0
200
1291
SPAT1262
SPAT
Handing over of treatment supplies
1.9
9.0
146
851
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.6
8.9
30
68
R53
ICD-10 Finland
Malaise and fatigue
1.8
8.9
160
966
A10AE04
ATC
insulin glargine; parenteral
2.3
8.9
80
364
R06AE07
ATC
cetirizine; oral
1.6
8.8
306
2242
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
8.7
87
416
B01AB04
ATC
dalteparin; parenteral
2.9
8.7
51
182
NFQ20
NOMESCO Finland
Amputation of femur
14.2
8.7
14
10
L14
ICPC
Leg/thigh symptom/complaint
2.5
8.7
68
287
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
7.8
8.7
19
25
SPAT1263
SPAT
Sampling
1.6
8.7
311
2290
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
16.5
8.6
13
8
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
10.2
8.6
16
16
L30.0
ICD-10 Finland
Nummular dermatitis
4.1
8.5
32
81
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
8.5
107
566
C08CA13
ATC
lercanidipine; oral
2.0
8.5
108
571
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
8.5
137
797
N19
ICD-10 Finland
Unspecified kidney failure
3.7
8.4
35
97
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.2
8.4
85
409
ZX112
NOMESCO Finland
Subcutaneous
4.6
8.4
28
63
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.9
8.4
33
87
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
91.0
8.4
9
*
XW000
NOMESCO Finland
Bone marrow biopsy
3.2
8.4
42
135
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
6.8
8.4
20
30
L94.2
ICD-10 Finland
Calcinosis cutis
+∞
8.3
8
*
L59.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue related to radiation, unspecified
+∞
8.3
8
*
L95.1
ICD-10 Finland
Erythema elevatum diutinum
+∞
8.3
8
*
M10.9
ICD-10 Finland
Gout, unspecified
2.7
8.3
57
225
ZX120
NOMESCO Finland
Intravenous
2.2
8.3
81
383
Z71.8
ICD-10 Finland
Other specified counselling
1.8
8.2
173
1092
XQ902
NOMESCO Finland
Other photography
14.7
8.2
13
9
L17
ICPC
Foot/toe symptom/complaint
1.7
8.2
190
1240
C01AA05
ATC
digoxin; systemic
2.4
8.1
71
319
SPAT1153
SPAT
Removal of sutures
1.6
8.1
236
1637
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
8.1
122
689
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
17.4
8.1
12
7
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.4
8.1
28
66
S19
ICPC
Skin injury other
3.4
8.0
37
112
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.5
8.0
36
107
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
7.3
8.0
18
25
A02BA02
ATC
ranitidine; systemic
1.8
8.0
154
949
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
8.0
84
413
E000002
ATC
NA
2.1
7.9
88
442
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.4
7.9
37
114
B01AB10
ATC
tinzaparin; parenteral
2.4
7.9
66
290
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.3
7.8
73
337
C08DB01
ATC
diltiazem; oral
2.7
7.8
53
208
A12BA01
ATC
potassium chloride; oral
2.8
7.7
49
184
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.0
7.6
29
75
C08CA02
ATC
felodipine; oral
2.2
7.6
81
399
B35.3
ICD-10 Finland
Tinea pedis
3.1
7.5
40
135
H02AB04
ATC
methylprednisolone; systemic
1.9
7.5
109
609
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.8
7.5
136
819
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
7.5
64
285
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
7.5
175
1140
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.1
7.4
80
395
A06AD11
ATC
lactulose; oral
1.9
7.3
116
668
S99
ICPC
Skin disease other
4.6
7.3
24
54
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
11.0
7.3
13
12
M36.4*D69.0
ICD-10 Finland
Arthropathy in Henoch(-Schönlein) purpura
+∞
7.3
7
*
L50.3
ICD-10 Finland
Dermatographic urticaria
6.3
7.3
18
29
I73.0
ICD-10 Finland
Raynaud syndrome
6.3
7.3
18
29
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
7.3
151
949
-56
ICPC
Dressing/pressure/compress/tamponade
5.5
7.3
20
37
NGQ20
NOMESCO Finland
Amputation of lower leg
15.9
7.2
11
7
M79.3
ICD-10 Finland
Panniculitis, unspecified
15.9
7.2
11
7
XQ800
NOMESCO Finland
Prick test
2.4
7.2
57
245
M05.2
ICD-10 Finland
Rheumatoid vasculitis
30.3
7.2
9
*
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.9
7.1
41
145
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.1
7.1
37
124
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.5
7.1
31
91
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
3.0
7.1
38
130
T90
ICPC
Diabetes non-insulin dependent
1.7
7.0
168
1103
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
6.9
165
1081
ZX108
NOMESCO Finland
Inhalation
8.4
6.8
14
17
160
Kela drug reimbursment
exenatide
4.6
6.8
22
49
D72.1
ICD-10 Finland
Eosinophilia
11.1
6.8
12
11
M31.0
ICD-10 Finland
Hypersensitivity angiitis
40.4
6.8
8
*
M31.3
ICD-10 Finland
Wegener granulomatosis
16.9
6.8
10
6
RJ411
NOMESCO Finland
NA
16.9
6.8
10
6
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
16.9
6.8
10
6
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
6.7
240
1739
A08
ICPC
Swelling
2.8
6.7
41
153
H26.3
ICD-10 Finland
Drug-induced cataract
22.7
6.7
9
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.8
6.7
114
672
R06AX27
ATC
desloratadine; oral
1.6
6.7
183
1244
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.6
6.7
28
80
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
5.6
6.6
18
33
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
3.8
6.6
26
70
M10.0
ICD-10 Finland
Idiopathic gout
3.2
6.6
32
102
A10BH01
ATC
sitagliptin; oral
2.1
6.6
72
358
C09AA05
ATC
ramipril; oral
1.6
6.6
182
1235
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
6.6
232
1676
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
6.6
197
1368
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.6
6.5
46
185
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
10.1
6.5
12
12
R03AC02
ATC
salbutamol; inhalant
1.5
6.5
365
2920
L50.0
ICD-10 Finland
Allergic urticaria
3.9
6.5
25
66
A10BB12
ATC
glimepiride; oral
2.3
6.5
60
277
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
3.0
6.5
37
129
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.8
6.5
39
144
C09AA02
ATC
enalapril; systemic
1.7
6.5
144
922
D89.1
ICD-10 Finland
Cryoglobulinaemia
70.4
6.4
7
*
L93.0
ICD-10 Finland
Discoid lupus erythematosus
70.4
6.4
7
*
TQW99
NOMESCO Finland
Other minor procedure on skin
2.8
6.4
39
145
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.1
6.4
71
357
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
14.5
6.4
10
7
T79.3
ICD-10 Finland
Post-traumatic wound infection, not elsewhere classified
6.6
6.4
15
23
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
8.2
6.3
13
16
WVA40
NOMESCO Finland
Initiation and monitoring of intravenous hydration
9.4
6.3
12
13
J01AA02
ATC
doxycycline; systemic
1.5
6.3
550
4820
A18.4
ICD-10 Finland
Tuberculosis of skin and subcutaneous tissue
+∞
6.3
6
*
L98.1
ICD-10 Finland
Factitial dermatitis
+∞
6.3
6
*
M30
ICD-10 Finland
Polyarteritis nodosa and related conditions
+∞
6.3
6
*
WX212
NOMESCO Finland
Femoral plexus blockade
4.2
6.2
22
54
L28
ICPC
Limited function/disability (L)
1.8
6.2
117
712
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.7
6.2
25
69
D07AA02
ATC
hydrocortisone; topical
1.9
6.2
98
561
E66.8
ICD-10 Finland
Other obesity
2.7
6.2
40
153
AA1AD
NOMESCO Finland
CT of head and brain
1.6
6.2
170
1153
A12AA04
ATC
calcium carbonate; oral
5.8
6.2
16
28
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
6.1
116
706
DHA10
NOMESCO Finland
Biopsy of cavity of nose
7.8
6.1
13
17
R4180
NOMESCO Finland
Podiatric therapy
7.8
6.1
13
17
R5110
SPAT
NA
3.7
6.1
25
70
C08CA05
ATC
nifedipine; systemic
2.4
6.1
52
230
P01AB01
ATC
metronidazole; oral, rectal
1.5
6.1
265
1998
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.1
6.1
31
103
QDA25
NOMESCO Finland
Destruction of lesion of skin of lower limb
12.6
6.1
10
8
UKC02
NOMESCO Finland
Cystoscopy
1.7
6.0
117
719
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
10.1
6.0
11
11
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
4.2
6.0
21
51
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.2
6.0
17
33
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.0
253
1897
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
283
215
19.46
315.73
2.0
1.5
98.6
210.0
titre
—
14
10
291
190
23.04
307.65
1.8
1.5
1.2
1.2
g/l
0.91
279
183
291
184
23.81
307.65
1.8
1.5
0.2
0.2
g/l
0.19
279
177
247
213
16.09
253.63
1.4
1.2
1.5
2.3
u/ml
0.17
18
12
152
195
9.32
114.72
2.6
1.9
—
—
—
0
0
233
557
5.43
95.42
2.3
2.9
67.1
66.3
g/l
0.76
217
502
118
159
8.49
84.76
1.3
1.2
4.4
14.2
u/ml
0.63
16
23
116
158
8.37
82.52
1.3
1.2
12.0
2.9
u/ml
—
9
15
103
130
8.90
77.89
1.3
1.2
1.3
11.8
u/ml
—
5
8
595
3179
4.08
76.38
12.0
5.7
61.3
57.6
%
11.56
576
2964
600
3226
4.10
76.25
12.8
5.9
24.3
27.4
%
10.08
582
2990
217
620
4.38
69.48
3.0
2.0
318.3
376.8
nmol/l
4.06
207
571
81
87
10.21
69.13
1.3
1.2
2.0
4.9
u/ml
0.59
32
30
654
3883
4.23
68.23
15.3
8.9
4.8
4.1
e9/l
9.20
606
3398
188
492
4.65
67.29
4.3
2.7
11.1
10.7
g/l
0.44
176
447
64
52
13.25
65.67
1.3
1.2
134.0
98.8
titre
—
15
8
90
124
8.02
63.01
1.4
1.2
39.7
43.6
u/ml
—
11
7
126
262
5.49
58.89
2.4
2.5
4.3
3.6
g/l
3.72
99
192
126
263
5.47
58.63
2.4
2.5
—
—
—
0
0
126
263
5.47
58.63
2.4
2.5
7.4
7.4
g/l
0.11
100
199
344
1475
3.28
58.55
4.3
2.5
5.5
5.9
e6/l
0.15
319
1311
479
2487
3.19
58.55
5.6
3.1
—
—
—
0
0
112
224
5.62
54.50
2.8
2.8
0.6
0.9
g/l
0.42
102
198
117
244
5.42
54.36
2.5
2.6
3.2
3.2
g/l
0.09
100
196
106
202
5.87
54.32
2.6
2.7
0.0
0.0
g/l
0.11
101
187
116
246
5.32
52.84
2.5
2.6
10.8
10.3
g/l
0.48
109
213
211
707
3.66
52.65
6.3
3.4
—
—
—
0
0
393
1918
2.99
51.93
5.2
3.1
0.3
0.5
e6/l
2.86
345
1456
94
192
5.39
44.46
2.7
2.8
0.0
0.0
g/l
0.49
89
177
64
89
7.71
44.20
1.4
1.2
2.4
6.6
u/ml
1.01
30
41
97
215
4.98
41.72
2.7
2.7
37.1
37.4
g/l
0.20
92
185
229
918
3.06
41.67
3.4
2.4
20.5
22.4
%
1.17
205
786
198
734
3.23
41.16
4.4
4.0
243.0
256.2
u/l
0.44
191
689
223
892
3.05
40.62
7.4
5.1
1.1
1.0
mmol/l
1.15
212
813
249
1066
2.91
40.04
3.2
2.3
11.3
12.8
umol/l
2.82
236
987
86
179
5.24
39.73
2.6
1.5
—
—
—
0
0
488
2934
2.61
39.44
7.9
4.7
33.6
35.4
g/l
9.38
468
2723
251
1096
2.85
38.74
1.3
1.3
33.3
34.1
iu/ml
0.05
75
344
36
27
13.89
38.44
1.1
1.1
1.0
1.1
ratio
—
19
9
231
980
2.88
37.48
3.3
2.3
2.3
2.3
g/l
1.19
217
908
171
622
3.20
36.34
2.6
2.3
0.2
0.2
g/l
0.47
161
579
50
67
7.88
35.56
1.5
1.1
—
—
u/ml
—
0
0
161
572
3.25
35.54
7.9
6.9
11.4
10.0
mmol/l
1.43
153
540
679
5008
2.96
33.14
8.5
4.0
18.7
12.6
mm/h
13.87
652
4602
64
120
5.70
33.07
4.8
3.3
4.8
4.3
e9/l
0.85
64
120
82
193
4.60
32.63
1.4
1.3
—
—
—
0
0
64
123
5.55
32.19
5.1
3.5
61.7
57.7
%
1.58
64
123
46
63
7.67
32.08
1.8
2.4
—
—
—
0
0
23
10
23.63
31.56
1.1
1.0
—
—
—
0
0
234
1097
2.58
30.41
3.8
3.2
0.8
0.8
mmol/l
4.28
220
1032
505
3338
2.31
29.58
6.1
3.6
0.0
0.0
estimate
0.00
179
623
314
1704
2.36
29.43
3.1
2.2
3.4
3.1
mg/l
1.24
281
1435
478
3109
2.27
28.81
8.2
5.9
1.2
1.2
mmol/l
0.77
433
2796
93
265
3.83
28.61
1.7
2.1
39.0
39.1
u/l
0.01
74
235
508
3398
2.28
28.46
9.2
6.6
1.2
1.2
mmol/l
1.00
402
2868
49
83
6.21
28.06
1.2
1.1
—
—
—
0
0
503
3377
2.24
27.56
6.1
3.7
0.0
0.0
estimate
0.50
177
601
47
78
6.33
27.45
1.2
1.1
132.8
118.2
%
1.04
47
72
498
3337
2.23
27.32
7.6
5.0
0.0
0.0
estimate
0.50
187
625
519
3548
2.24
26.92
8.3
6.1
11.0
11.5
umol/l
0.56
503
3357
434
2771
2.19
26.66
3.0
2.2
77.7
77.1
nmol/l
0.16
403
2449
681
5243
2.66
26.59
13.5
7.3
82.3
78.5
u/l
1.58
660
4891
115
395
3.22
26.47
1.6
1.2
282.5
265.1
u/ml
0.06
109
358
308
1719
2.26
26.44
3.8
2.6
4543.9
8750.4
umol/l
0.92
278
1476
442
2867
2.16
25.78
3.9
2.7
176.0
133.2
ug/l
1.15
410
2620
316
1798
2.22
25.73
7.1
3.9
0.0
0.0
estimate
0.69
180
600
68
171
4.24
24.77
2.0
2.9
220.3
196.7
%
1.06
63
165
226
1137
2.36
24.50
2.4
1.8
—
—
—
0
0
129
495
2.90
24.40
2.4
1.5
—
—
—
0
0
30
34
9.12
24.30
1.2
1.2
—
—
—
0
0
78
221
3.79
24.12
3.4
3.8
35.0
47.6
mg/l
0.43
62
180
77
217
3.81
23.99
3.4
3.7
2.5
1.9
ratio
—
10
22
68
176
4.12
23.83
4.0
4.0
1.8
1.6
mg/l
0.65
63
158
88
273
3.49
23.77
2.8
1.8
2.5
3.0
ug/l
0.11
80
237
77
220
3.76
23.51
3.5
3.8
56.5
87.3
mg/l
0.51
61
178
135
549
2.74
22.82
5.4
3.6
1.2
1.2
mmol/l
0.73
123
475
337
2052
2.08
22.30
2.7
2.1
143.3
245.5
u/l
1.85
313
1930
57
136
4.43
22.20
4.5
2.1
15.8
15.5
%
0.13
30
67
91
301
3.27
22.18
1.5
2.0
1.5
1.5
g/l
0.20
77
264
64
171
3.97
21.46
1.8
2.2
11.4
12.4
mg/l
0.35
57
157
547
4022
2.06
20.88
6.4
4.7
6.9
6.7
mmol/l
1.28
526
3766
341
2129
2.02
20.69
5.6
3.8
17.0
9.0
mg/mmol
1.55
248
1326
341
2147
2.00
20.04
4.4
3.0
6.9
7.6
mmol/l
2.38
295
1784
593
4523
2.09
20.04
7.0
4.5
10.2
3403.2
e6/l
—
6
73
67
198
3.59
19.43
1.6
1.6
0.2
0.1
iu/ml
0.49
22
44
331
2083
1.98
19.31
4.1
3.1
1859.0
1409.1
ng/l
1.16
297
1769
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
70
220
3.38
18.47
4.2
2.7
0.3
0.4
u/ml
1.20
44
122
26
35
7.64
18.32
2.3
1.7
12.4
11.9
%
—
10
18
31
52
6.15
17.88
1.3
1.2
—
—
—
0
0
31
52
6.15
17.88
1.3
1.2
—
—
—
0
0
31
53
6.04
17.55
1.3
1.2
—
—
—
0
0
31
53
6.04
17.55
1.3
1.2
—
—
—
0
0
31
53
6.04
17.55
1.3
1.2
—
—
—
0
0
159
789
2.26
17.21
2.2
1.8
—
—
—
0
0
159
791
2.25
17.10
2.2
1.8
—
—
—
0
0
24
32
7.69
17.04
2.6
1.8
—
—
—
0
0
380
2589
1.86
16.78
6.6
3.8
—
—
—
0
0
70
235
3.16
16.58
2.0
2.0
256.2
435.9
ug/l
0.44
60
220
191
1049
2.07
15.85
1.4
1.3
7.6
12.1
u/ml
0.66
65
386
198
1103
2.04
15.80
4.1
2.9
3.7
2.5
e6/l
0.79
127
602
136
659
2.27
15.49
5.8
3.8
1.7
2.1
mmol/l
0.53
116
523
268
1669
1.89
15.40
1.9
1.5
19.9
20.9
nmol/l
0.46
233
1396
244
1485
1.91
14.98
1.9
1.7
1.2
1.2
mg/l
0.13
204
1127
319
2124
1.82
14.65
3.3
2.5
52.5
57.2
u/l
1.94
291
1958
344
2352
1.79
14.39
4.0
3.4
2.3
2.4
mmol/l
0.58
308
2037
92
388
2.54
14.23
1.8
1.5
—
—
—
0
0
34
78
4.50
13.91
1.3
1.7
—
—
—
0
0
200
1169
1.94
13.70
3.9
2.7
0.9
1.2
e6/l
0.90
127
662
50
156
3.35
13.34
1.6
1.5
—
—
—
0
0
26
50
5.34
13.03
1.3
1.7
—
—
—
0
0
114
550
2.24
13.03
5.7
3.6
102.0
83.4
ng/l
1.23
103
478
156
856
2.01
12.75
7.1
6.6
104.0
104.2
mmol/l
0.24
150
832
217
1336
1.85
12.53
2.0
1.7
1323.2
1174.5
nmol/l
1.44
175
1000
36
96
3.87
12.12
1.4
1.6
—
—
—
0
0
63
238
2.78
12.11
2.7
3.0
—
—
—
0
0
13
12
10.99
11.98
2.8
1.6
—
—
—
0
0
49
162
3.15
11.91
1.3
1.7
—
—
—
0
0
39
113
3.57
11.66
1.4
1.4
112.1
111.8
u/ml
0.01
13
15
313
2186
1.69
11.49
3.7
3.2
36.7
32.8
u/l
0.62
283
2082
41
126
3.37
11.22
1.3
1.2
272.0
245.2
u/ml
0.19
22
71
40
121
3.42
11.21
1.5
1.7
—
—
—
0
0
79
347
2.41
11.18
6.1
4.3
23.7
24.4
mmol/l
1.30
73
318
53
193
2.87
10.91
1.4
1.1
—
—
—
0
0
138
768
1.96
10.72
3.0
2.4
124.5
133.1
ug/g
0.16
108
601
46
157
3.04
10.61
1.4
1.6
—
—
—
0
0
41
131
3.24
10.56
1.2
1.2
—
—
—
0
0
36
107
3.47
10.38
4.0
3.4
1.2
1.3
%
0.07
29
86
45
154
3.03
10.34
1.5
1.6
—
—
—
0
0
27
66
4.19
10.22
1.3
1.2
46.1
52.5
u/l
0.41
22
50
12
13
9.35
9.89
1.2
1.1
—
—
—
0
0
20
39
5.23
9.87
1.9
1.6
7.2
9.8
u/l
0.18
13
21
140
805
1.89
9.82
6.0
7.6
1.3
1.3
mmol/l
0.03
105
626
92
456
2.14
9.78
5.7
3.7
5.3
5.2
kpa
0.37
87
424
88
429
2.18
9.75
5.7
3.7
2.3
2.0
mmol/l
0.34
70
320
20
40
5.10
9.61
2.5
1.7
459.0
500.0
e6/l
0.14
15
32
41
139
3.05
9.58
1.5
1.3
—
—
—
0
0
41
139
3.05
9.58
1.5
1.3
—
—
—
0
0
34
104
3.37
9.39
1.5
1.3
—
—
—
0
0
134
773
1.87
9.28
3.1
2.7
9.1
8.2
umol/l
0.21
114
661
111
608
1.95
8.98
2.5
2.3
47.4
33.9
u/l
0.65
100
513
137
806
1.84
8.90
6.1
7.6
5.0
5.1
kpa
0.30
127
770
13
18
7.32
8.86
1.1
1.1
—
—
—
0
0
220
1488
1.65
8.69
1.9
1.7
431.8
25989138.4
pmol/l
1.42
182
1239
641
5560
1.67
8.67
38.6
17.7
14.3
13.7
%
15.19
634
5441
354
2684
1.56
8.63
5.9
3.7
50.0
49.9
ng/l
0.00
272
1897
136
807
1.82
8.58
6.1
7.6
11.7
12.0
kpa
0.39
127
771
402
3149
1.54
8.38
5.3
4.0
—
—
—
0
0
42
156
2.78
8.37
3.6
3.1
33.7
34.2
umol/l
0.05
32
128
30
93
3.31
8.14
1.3
1.5
—
—
—
0
0
35
121
2.98
7.94
1.2
1.2
89.4
41.1
u/l
0.47
26
107
599
5159
1.58
7.82
4.4
3.8
15.1
14.9
pmol/l
1.86
536
4635
40
151
2.73
7.75
4.4
2.0
125.3
125.5
g/l
0.02
35
111
144
897
1.73
7.66
29.4
25.3
1.5
1.3
inr
0.45
21
115
741
6761
1.90
7.58
35.6
14.2
21.6
24.3
mg/l
2.06
681
5334
364
2834
1.51
7.55
2.3
2.0
91.7
94.6
pmol/l
0.53
211
1450
522
4381
1.52
7.50
4.3
3.1
68.6
49.0
u/l
4.14
482
4076
191
1289
1.63
7.49
4.8
4.0
277.6
316.4
ng/l
0.10
154
1024
36
136
2.72
6.98
1.7
1.6
—
—
—
0
0
32
114
2.88
6.91
1.3
1.5
—
—
—
0
0
93
524
1.87
6.89
4.8
2.6
58.0
66.5
ml/min/173m2
1.37
55
216
29
98
3.03
6.87
1.3
1.5
—
—
—
0
0
27
88
3.14
6.79
1.3
1.5
—
—
—
0
0
193
1334
1.58
6.79
3.4
3.1
2.5
2.5
mmol/l
3.91
172
1169
25
78
3.27
6.74
2.7
1.6
52.2
60.9
%
0.39
13
59
15
32
4.76
6.71
1.5
1.6
—
—
—
0
0
18
45
4.07
6.65
2.7
1.9
881.4
825.1
e6/l
—
7
19
12
21
5.78
6.60
4.2
3.8
—
—
—
0
0
15
33
4.61
6.48
1.5
1.6
—
—
—
0
0
204
1442
1.55
6.47
1.3
1.2
1.8
1.9
u/ml
0.05
69
377
71
373
1.99
6.47
5.3
9.0
24.4
24.7
mmol/l
0.29
65
347
21
61
3.51
6.32
1.2
1.3
—
—
—
0
0
13
26
5.06
6.24
2.4
1.7
125.4
54.4
ug/l
0.54
13
26
14
31
4.58
6.00
1.0
1.3
—
—
—
0
0
28
102
2.81
5.84
1.1
1.1
—
—
—
0
0
42
187
2.31
5.83
1.9
1.4
—
—
—
0
0
98
591
1.75
5.81
3.9
3.1
258.3
223.6
ng/l
0.35
89
547
16
41
3.96
5.73
1.4
1.5
—
—
—
0
0
10
17
5.94
5.63
1.1
1.1
—
—
—
0
0
156
1078
1.55
5.40
1.5
1.5
—
—
—
0
0
15
39
3.90
5.28
3.3
4.3
—
—
—
0
0
18
54
3.39
5.19
1.4
2.4
738.8
629.6
ml
0.29
12
34
22
76
2.95
5.06
1.3
1.3
—
—
—
0
0
681
6261
1.49
4.60
7.2
5.8
41.4
40.0
mmol/mol
2.91
636
5756
35
167
2.14
4.19
3.8
3.3
0.8
0.9
nmol/l
0.26
25
130
41
208
2.02
4.18
4.1
3.7
3.9
3.9
mmol/l
0.14
34
192
58
331
1.81
4.18
5.4
3.1
25.2
25.1
mmol/l
0.08
58
326
9
13
6.98
4.17
1.0
1.2
—
—
—
0
0
672
6199
1.44
4.11
5.4
4.7
2.0
1.9
mu/l
0.45
615
5603
12
32
3.79
4.09
1.8
2.5
954.2
713.0
u/ml
0.39
12
32
69
418
1.71
4.06
2.5
1.6
—
—
—
0
0
36
176
2.09
4.06
2.2
2.4
116.2
46.1
ug/min
0.66
20
104
13
38
3.46
3.91
1.3
1.2
5.3
8.2
u/l
0.78
13
32
14
44
3.22
3.79
1.1
1.2
—
—
—
0
0
14
44
3.22
3.79
1.1
1.2
—
—
—
0
0
18
66
2.77
3.77
2.6
1.6
—
—
—
0
0
685
6373
1.43
3.71
30.6
13.2
77.7
79.5
ml/min/173m2
1.08
631
5216
70
437
1.66
3.70
9.3
7.6
24.5
24.5
mmol/l
0.04
65
407
34
171
2.03
3.59
1.8
1.7
10726.8
17167.7
e6/l
0.63
26
124
457
4024
1.30
3.46
3.1
2.9
—
—
—
0
0
12
37
3.28
3.35
1.3
1.6
—
—
—
0
0
17
65
2.65
3.32
6.0
2.8
51.3
58.8
%
0.52
11
44
9
19
4.78
3.24
1.2
1.2
—
—
—
0
0
30
150
2.04
3.24
1.3
1.4
13.1
9.1
u/l
0.72
22
116
31
157
2.01
3.23
1.2
1.1
—
—
—
0
0
7
11
6.41
3.19
1.4
1.5
—
—
—
0
0
6
8
7.54
3.06
1.3
1.4
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
10
30
3.36
2.91
1.1
1.1
—
—
—
0
0
736
7004
1.45
2.91
35.9
16.6
139.1
139.7
mmol/l
6.17
722
6815
16
64
2.53
2.88
1.1
1.1
—
—
—
0
0
7
13
5.42
2.87
1.1
1.3
—
—
—
0
0
22
103
2.17
2.83
1.1
1.1
—
—
—
0
0
203
1641
1.31
2.80
3.1
2.3
—
—
—
0
0
8
18
4.48
2.80
1.0
1.0
—
—
—
0
0
19
84
2.29
2.79
1.4
1.4
1670.3
1489.0
e6/l
0.09
12
59
10
31
3.25
2.78
1.3
1.2
—
—
—
0
0
10
31
3.25
2.78
1.1
1.1
—
—
—
0
0
752
7202
1.47
2.69
20.5
10.2
26.5
26.0
u/l
0.39
732
6929
736
7022
1.43
2.68
36.2
16.7
4.0
4.0
mmol/l
0.21
719
6820
8
19
4.24
2.68
3.4
1.6
—
—
—
0
0
17
74
2.32
2.59
1.5
1.3
11472.3
49349.6
e6/l
—
8
43
11
38
2.92
2.59
1.0
1.0
—
—
—
0
0
30
166
1.84
2.48
1.4
1.3
—
—
—
0
0
28
152
1.87
2.45
1.6
2.0
3104.5
2639.2
u/l
—
8
58
8
22
3.66
2.37
1.3
1.1
11.9
8.7
ug/l
—
8
22
81
582
1.43
2.34
2.7
2.5
5.4
7.3
ug/l
0.96
68
506
102
766
1.38
2.30
2.0
1.8
1.8
1.5
%
2.71
86
672
32
524
0.60
2.22
1.5
1.7
—
—
—
0
0
5
9
5.58
2.21
11.6
10.2
4.2
7.1
mmol/l
—
5
9
33
198
1.69
2.11
1.4
1.5
274.3
298.3
ug/g
0.28
21
124
34
207
1.67
2.07
1.6
1.6
—
—
—
0
0
43
280
1.56
2.02
2.7
1.8
—
—
—
0
0
15
70
2.16
1.99
1.0
1.3
—
—
—
0
0
7
21
3.35
1.97
1.1
1.0
—
—
—
0
0
17
84
2.05
1.96
1.5
1.2
0.5
0.6
nmol/l
0.99
17
79
29
173
1.70
1.92
1.3
1.3
213.0
227.1
miu/ml
—
7
81
26
152
1.73
1.85
1.6
1.3
—
—
—
0
0
5
12
4.19
1.82
1.0
1.0
—
—
—
0
0
7
23
3.06
1.80
1.0
1.0
1302.3
1523.5
miu/ml
—
7
23
13
60
2.19
1.78
1.8
1.4
9311.7
73508.5
e6/l
—
6
40
65
872
0.72
1.74
5.3
4.5
31.9
32.3
%
0.12
47
570
39
259
1.53
1.71
2.5
1.7
—
—
—
0
0
6
19
3.17
1.66
1.8
2.9
—
—
—
0
0
8
31
2.60
1.66
1.0
1.0
—
—
—
0
0
16
83
1.95
1.65
1.1
1.0
—
—
—
0
0
7
25
2.81
1.65
1.6
1.3
73.7
97.0
nmol/l
—
7
17
10
43
2.34
1.60
1.0
1.3
—
—
—
0
0
7
26
2.71
1.58
1.3
1.9
—
—
—
0
0
56
408
1.40
1.56
1.2
1.2
135.8
139.2
iu/ml
0.02
26
168
12
57
2.12
1.55
1.7
1.5
—
—
—
0
0
12
57
2.12
1.55
1.7
1.5
—
—
—
0
0
12
57
2.12
1.55
1.7
1.5
—
—
—
0
0
17
93
1.85
1.52
1.1
1.1
—
—
—
0
0
11
52
2.13
1.45
1.0
1.1
—
—
—
0
0
9
40
2.26
1.40
1.7
1.2
—
—
—
0
0
9
40
2.26
1.40
1.3
1.2
—
—
—
0
0
9
40
2.26
1.40
1.7
1.2
—
—
—
0
0
22
134
1.66
1.40
1.1
1.5
5.6
153.4
e6/l
1.50
14
109
22
134
1.66
1.40
1.1
1.4
7.8
33.2
e6/l
0.51
13
104
31
206
1.52
1.39
1.3
1.1
—
—
—
0
0
12
60
2.01
1.38
1.5
1.3
—
—
—
0
0
9
43
2.10
1.30
1.6
1.6
—
—
—
0
0
637
6105
1.19
1.30
29.5
15.7
38.4
39.7
%
2.51
408
4298
173
1506
1.19
1.21
7.1
3.9
1.0
1.0
kg/l
0.60
25
214
13
222
0.58
1.15
1.2
1.7
—
—
—
0
0
48
624
0.76
1.10
2.9
2.0
—
—
—
0
0
8
41
1.96
1.09
1.1
2.0
—
—
—
0
0
32
229
1.41
1.05
1.6
1.3
19.2
28.1
iu/l
1.04
26
191
5
22
2.28
1.03
2.8
3.3
—
—
—
0
0
5
22
2.28
1.03
2.8
3.3
—
—
—
0
0
7
34
2.07
1.03
2.0
1.5
—
—
—
0
0
7
34
2.07
1.03
2.0
1.5
—
—
—
0
0
7
34
2.07
1.03
2.0
1.5
—
—
—
0
0
7
34
2.07
1.03
2.0
1.5
—
—
—
0
0
7
36
1.95
0.97
1.1
1.6
—
—
—
0
0
7
36
1.95
0.97
1.1
1.6
—
—
—
0
0
657
6370
1.15
0.90
4.2
3.9
1.4
1.3
mmol/l
3.66
592
5774
28
203
1.39
0.88
1.3
1.1
—
—
—
0
0
12
72
1.68
0.85
1.7
1.6
—
—
—
0
0
765
7516
1.23
0.84
46.9
21.0
4.3
4.5
e12/l
12.78
751
7291
6
31
1.94
0.84
1.8
1.1
—
—
—
0
0
6
31
1.94
0.84
1.8
1.1
—
—
—
0
0
45
565
0.78
0.83
2.8
1.9
—
—
—
0
0
765
7519
1.22
0.82
47.3
21.1
129.6
135.0
g/l
18.56
757
7390
43
339
1.28
0.80
1.3
1.3
—
—
—
0
0
10
58
1.73
0.80
1.0
1.0
—
—
—
0
0
16
106
1.52
0.79
1.3
1.1
0.5
2.7
u/ml
—
9
45
9
54
1.67
0.74
1.3
1.1
1.3
1.6
nmol/l
—
9
46
5
25
2.01
0.72
2.4
1.6
—
—
—
0
0
5
25
2.01
0.72
2.4
1.6
—
—
—
0
0
11
68
1.63
0.72
1.7
1.7
—
—
—
0
0
5
26
1.93
0.70
2.4
1.6
—
—
—
0
0
9
58
1.56
0.70
2.8
2.2
—
—
—
0
0
86
744
1.17
0.69
3.9
4.2
92.3
30.6
ug/l
0.51
70
619
13
85
1.54
0.69
3.7
3.7
—
—
—
0
0
5
27
1.86
0.68
3.2
2.3
64.4
47.3
umol/l
—
5
19
46
375
1.24
0.68
2.2
3.2
4.1
4.5
pmol/l
2.32
39
337
674
6592
1.12
0.62
5.1
4.6
6.0
6.0
mmol/l
0.22
614
5961
680
6658
1.12
0.59
4.7
4.4
4.4
4.6
mmol/l
8.07
610
6124
10
64
1.57
0.58
1.1
1.1
—
—
—
0
0
6
36
1.67
0.56
1.2
1.2
—
—
—
0
0
692
6788
1.12
0.56
5.1
4.9
2.5
2.7
mmol/l
8.41
617
6210
674
6610
1.10
0.52
4.6
4.3
1.4
1.5
mmol/l
4.35
605
6037
22
172
1.29
0.48
1.0
1.2
—
—
—
0
0
15
111
1.36
0.47
1.5
1.5
—
—
—
0
0
7
49
1.43
0.46
1.6
1.9
18.3
22.3
nmol/l
—
7
44
5
31
1.62
0.43
1.0
1.3
—
—
—
0
0
5
31
1.62
0.43
1.8
1.1
—
—
—
0
0
5
32
1.57
0.42
11.8
3.6
209.2
218.1
u/l
—
5
32
10
71
1.41
0.39
1.7
1.7
—
—
—
0
0
25
302
0.82
0.39
1.8
1.9
—
—
—
0
0
12
89
1.35
0.38
2.3
1.2
—
—
—
0
0
12
89
1.35
0.38
2.3
1.2
—
—
—
0
0
12
89
1.35
0.38
2.2
1.2
—
—
—
0
0
12
90
1.34
0.36
2.3
1.2
—
—
—
0
0
9
122
0.73
0.35
2.3
1.8
—
—
—
0
0
12
91
1.32
0.34
2.3
1.2
—
—
—
0
0
12
91
1.32
0.34
2.3
1.2
—
—
—
0
0
14
176
0.79
0.32
2.2
1.8
34.1
39.2
nmol/l
0.47
14
166
15
183
0.82
0.27
1.5
1.5
—
—
—
0
0
36
328
1.10
0.18
2.3
2.8
47.1
59.3
u/ml
0.21
36
315
52
484
1.08
0.18
2.8
2.2
12.9
13.4
nmol/l
0.12
41
424
7
62
1.13
0.17
1.6
1.3
—
—
—
0
0
7
63
1.11
0.17
1.1
1.5
—
—
—
0
0
5
70
0.71
0.16
1.0
1.6
—
—
—
0
0
17
149
1.14
0.15
1.0
1.4
1.2
0.9
nmol/l
0.44
12
126
95
916
1.04
0.12
1.5
1.4
—
—
—
0
0
218
2138
1.03
0.11
4.8
4.9
2.4
2.9
ug/l
0.43
193
1907
178
1812
0.98
0.08
1.7
1.6
1.4
1.4
mmol/l
0.31
135
1537
17
184
0.92
0.07
1.3
1.5
—
—
—
0
0
168
1708
0.98
0.07
4.0
4.2
21.8
21.2
%
0.17
74
807
9
86
1.05
0.07
1.6
1.6
—
—
—
0
0
17
182
0.93
0.05
1.4
1.4
—
—
—
0
0
123
1246
0.98
0.04
2.6
2.9
0.6
0.8
ug/l
1.04
86
805
23
237
0.97
0.01
1.8
1.9
—
—
—
0
0
30
305
0.98
0.00
1.0
1.0
—
—
—
0
0
86
865
0.99
0.00
13.6
6.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
0.6
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_VASCULITISNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_VASCULITISNAS | 2.781 [2.39, 3.24] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.216 |
During the follow-up period (1.1.1998 — 31.12.2019), 1063 out of 2856 females with L12_VASCULITISNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| L12_VASCULITISNAS | 2.679 [2.22, 3.24] | < 0.001 |
| Birth year | 0.99 [0.98, 1.0] | 0.032 |
During the follow-up period (1.1.1998 — 31.12.2019), 699 out of 1962 males with L12_VASCULITISNAS died.
Mortality risk
Mortality risk for people of age
years, who have L12_VASCULITISNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.272% | 0.627% |
| 5 | 1.768% | 3.441% |
| 10 | 4.143% | 8.225% |
| 15 | 8.192% | 15.612% |
| 20 | 13.626% | 25.911% |
Relationships between endpoints
↥Index endpoint: L12_VASCULITISNAS – Other and unspecified vasculitis limited to skin
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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