No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
224 |
4. Check minimum number of eventsNone |
224 |
5. Include endpointsNone |
224 |
6. Filter based on genotype QC (FinnGen only) |
210 |
Control definitions (FinnGen only)
- Control exclude
- N14_UROLITHIASIS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- N20-N23
- Name in latin
- Colica renalis non specificata
Similar endpoints
↥List of similar endpoints to
Unspecified renal colic
based on the number of shared cases.
Similar with more cases:
- Urolithiasis
- All kidney diseases
- Genitourinary diseases
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1579 | 646 | 917 |
| Only index persons | 1527 | 638 | 889 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.03 |
| Only index persons | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | |||
| Whole population | 51.25 | 48.54 | 53.44 |
| Only index persons | 51.02 | 48.38 | 52.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 210 | 100 | 110 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.05 |
| Median age at first event (years) | 53.99 | 51.23 | 56.50 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 224
- Matched controls
- 2240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N23
ICD-10 Finland
Unspecified renal colic
+∞
321.1
223
*
KH1AD
NOMESCO Finland
CT of urinary organs
82.4
146.0
80
15
N20.1
ICD-10 Finland
Calculus of ureter
718.8
97.3
89
*
N20.9
ICD-10 Finland
Urinary calculus, unspecified
651.4
53.9
51
*
N20.0
ICD-10 Finland
Calculus of kidney
509.1
43.8
42
*
KH1AA
NOMESCO Finland
Urinary tract X-ray examination without contrast
319.2
28.4
28
*
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
85.9
27.5
30
*
KBE12
NOMESCO Finland
Transluminal endoscopic extraction of calculus of ureter
+∞
23.3
22
*
KAT00
NOMESCO Finland
Extracorporeal shock wave lithotripsy of pelvis of kidney
+∞
22.3
21
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.6
21.0
37
65
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.6
20.3
121
548
UKB02
NOMESCO Finland
Retrograde ureteroscopy
194.8
17.8
18
*
UKC02
NOMESCO Finland
Cystoscopy
3.8
16.1
60
196
N20.2
ICD-10 Finland
Calculus of kidney with calculus of ureter
+∞
15.8
15
*
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
61.0
15.0
17
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
3.1
12.6
69
283
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.5
12.2
48
160
G04CA02
ATC
tamsulosin; oral
2.9
11.7
76
341
5921A
ICD-9 Finland
Calculus of kidney and ureter, Calculus of ureter
+∞
10.5
10
*
KAE12
NOMESCO Finland
Retrograde ureteronephroscopic lithotripsy in pelvis of kidney
+∞
10.5
10
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.4
10.2
42
144
KBV10
NOMESCO Finland
Removal of stent from ureter
57.6
9.7
11
*
N02AX02
ATC
tramadol; systemic, rectal
2.4
9.5
114
673
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.1
8.8
41
151
R31
ICD-10 Finland
Unspecified haematuria
3.4
8.8
35
117
A02BC02
ATC
pantoprazole; systemic
2.5
8.4
164
1174
U95
ICPC
Urinary calculus
+∞
8.4
8
*
N21.0
ICD-10 Finland
Calculus in bladder
+∞
8.4
8
*
R07.3
ICD-10 Finland
Other chest pain
3.2
8.1
35
123
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
11.4
7.9
14
13
ZXA05
NOMESCO Finland
Left side
2.4
7.7
64
317
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
7.5
70
363
N13.0
ICD-10 Finland
Hydronephrosis with ureteropelvic junction obstruction
+∞
7.3
7
*
R51.80
ICD-10 Finland
Headache
2.5
7.1
51
235
KA1FN
NOMESCO Finland
Isotope renography
41.3
6.8
8
*
G44.2
ICD-10 Finland
Tension-type headache
2.6
6.7
42
180
G47.3
ICD-10 Finland
Sleep apnoea
2.3
6.5
63
331
KH1BD
NOMESCO Finland
Extensive urinary tract CT examination
18.7
6.3
9
5
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.1
54
272
R02
ICPC
Shortness of breath/dyspnoea
2.7
6.0
34
138
M01AB55
ATC
diclofenac, combinations; oral
3.5
6.0
21
64
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
113
634
2.58
10.98
4.5
3.3
—
—
—
0
0
94
508
2.47
9.59
4.7
3.1
0.38
0.54
e6/l
0.45
76
377
164
1150
2.59
9.21
6.9
4.2
3968.20
207.75
e6/l
—
5
20
61
288
2.54
8.13
2.9
2.6
1.53
0.89
e6/l
0.63
33
159
58
272
2.53
7.82
3.0
2.8
2.10
2.18
e6/l
0.03
30
142
83
467
2.23
7.35
2.7
2.7
333.68
6826.90
umol/l
2.18
72
416
18
45
4.26
6.76
1.2
1.4
274.00
269.29
ug/g
—
8
22
128
889
2.03
6.22
4.7
3.5
0.00
0.00
estimate
-0.00
27
162
127
880
2.02
6.20
6.2
4.8
0.00
0.00
estimate
-0.00
29
170
62
331
2.21
6.09
5.0
3.3
570.41
220.03
ng/l
0.37
46
245
126
879
1.99
5.95
4.8
3.5
0.00
0.01
estimate
0.50
30
184
119
841
1.89
5.14
9.4
6.3
1.21
1.21
mmol/l
0.30
108
712
26
100
2.81
5.10
5.3
5.4
25.39
24.79
mmol/l
0.38
26
100
89
580
1.89
4.89
3.1
3.3
2.34
2.34
mmol/l
0.05
82
523
109
763
1.83
4.73
8.8
5.3
1.20
1.21
mmol/l
0.66
104
693
213
1890
3.59
4.62
21.6
15.0
139.74
139.62
mmol/l
0.31
208
1837
213
1897
3.50
4.44
21.7
15.0
3.98
3.97
mmol/l
0.13
207
1843
216
1974
3.64
4.33
21.3
15.5
85.63
77.90
umol/l
1.32
216
1974
171
1408
1.91
4.08
8.8
7.4
83.34
79.01
u/l
0.27
164
1324
137
1057
1.76
4.05
6.1
4.4
6.74
6.67
mmol/l
0.14
129
983
116
855
1.74
4.03
2.5
2.5
—
—
—
0
0
194
1682
2.15
3.79
4.7
4.5
1.81
1.87
mu/l
0.31
174
1552
84
577
1.73
3.67
3.0
2.6
61.61
62.72
u/l
0.05
76
540
37
195
2.08
3.66
1.6
1.8
—
—
—
0
0
166
1379
1.79
3.55
4.1
3.8
14.54
14.69
pmol/l
0.34
150
1252
151
1222
1.72
3.54
3.2
3.2
—
—
—
0
0
66
428
1.77
3.50
2.2
2.2
—
—
—
0
0
199
1758
2.18
3.45
17.1
12.2
81.02
84.09
ml/min/173m2
1.20
181
1453
102
749
1.66
3.43
5.0
4.9
35.98
35.88
g/l
0.07
94
707
124
958
1.66
3.41
5.4
6.4
11.96
11.95
umol/l
0.00
117
915
205
1843
2.32
3.21
20.5
13.4
19.58
23.09
mg/l
1.01
169
1439
39
221
1.93
3.16
2.0
3.3
5.06
11.69
umol/l
1.93
34
199
36
199
1.96
3.13
1.6
1.9
—
—
—
0
0
96
708
1.62
3.09
5.1
3.6
—
—
—
0
0
108
821
1.61
3.06
14.3
12.7
1.16
1.24
inr
0.57
34
252
163
1371
1.69
3.06
5.2
3.9
12.15
11.33
mm/h
0.26
147
1252
34
186
1.98
3.04
2.8
3.5
—
—
—
0
0
35
194
1.95
3.02
8.0
6.6
1.13
1.12
mmol/l
0.01
28
152
61
404
1.70
2.96
2.0
1.6
1.07
1.06
mg/l
0.01
44
312
31
166
2.01
2.94
8.7
6.9
123.65
122.23
g/l
0.15
31
160
19
83
2.41
2.93
1.7
1.6
—
—
—
0
0
87
635
1.61
2.88
2.9
3.4
28.18
30.54
u/l
0.44
79
604
69
476
1.65
2.86
5.8
3.7
0.00
0.00
estimate
-0.00
28
166
130
1044
1.58
2.85
8.6
9.1
4.12
4.24
e9/l
0.24
114
908
69
480
1.63
2.76
3.0
2.9
2326.12
1401.64
ng/l
0.52
57
406
92
694
1.55
2.59
4.2
3.6
26.92
40.43
ng/l
0.91
54
471
9
26
3.56
2.51
1.1
1.1
—
—
—
0
0
5
8
6.36
2.38
1.2
1.1
—
—
—
0
0
44
284
1.68
2.32
1.7
1.9
—
—
—
0
0
151
1296
1.51
2.16
3.7
3.3
44.53
47.73
u/l
0.18
137
1228
67
489
1.53
2.13
1.8
1.6
1.27
1.38
mmol/l
0.62
55
409
20
106
1.97
1.98
7.2
7.2
0.75
0.69
%
0.21
20
106
5
11
4.62
1.95
1.2
1.8
—
—
—
0
0
187
1696
1.62
1.94
6.3
5.5
41.49
39.77
mmol/mol
1.41
177
1600
194
1776
1.69
1.93
4.8
4.2
6.07
5.93
mmol/l
0.70
180
1637
20
107
1.95
1.93
7.1
6.8
1.34
1.52
%
0.29
20
107
9
36
2.56
1.76
1.6
1.2
—
—
—
0
0
9
36
2.56
1.76
1.6
1.2
—
—
—
0
0
6
18
3.39
1.76
5.3
2.7
3.22
3.86
nmol/l
—
6
18
20
111
1.88
1.75
2.3
3.2
1.34
1.37
mmol/l
0.02
14
77
11
48
2.36
1.73
3.1
2.6
22.80
23.67
mmol/l
0.35
11
48
86
686
1.41
1.69
2.0
1.9
93.69
95.46
pmol/l
0.17
53
351
216
2069
2.23
1.67
27.7
19.5
4.58
4.53
e12/l
0.87
211
2024
216
2067
2.26
1.66
28.1
19.5
41.04
40.52
%
0.57
202
1967
6
20
3.05
1.59
1.0
1.2
—
—
—
0
0
52
384
1.46
1.53
4.7
3.8
1.02
1.02
kg/l
—
10
48
42
297
1.51
1.53
1.5
1.3
3.93
7.70
u/ml
0.55
16
116
17
94
1.87
1.52
1.1
1.0
—
—
—
0
0
33
222
1.57
1.49
5.6
5.8
105.12
104.16
mmol/l
0.78
33
222
56
425
1.42
1.43
1.2
1.3
0.58
0.75
u/ml
0.46
12
113
40
285
1.49
1.41
2.0
1.7
31.19
29.18
s
1.13
40
276
42
304
1.47
1.37
1.4
1.3
14.40
32.35
iu/ml
—
9
99
18
106
1.76
1.34
1.2
1.3
191.72
167.51
u/ml
0.09
18
97
65
512
1.38
1.34
5.4
3.9
8.64
8.97
mg/mmol
0.03
47
335
46
341
1.44
1.33
1.6
1.5
—
—
—
0
0
5
18
2.82
1.29
1.6
1.3
—
—
—
0
0
13
70
1.91
1.27
10.5
5.5
3.15
1.64
%
0.38
13
63
24
157
1.59
1.23
4.6
3.8
1.56
2.13
mmol/l
0.34
18
124
35
252
1.46
1.18
4.1
2.3
23.79
23.99
%
0.03
29
223
8
40
2.04
1.13
1.1
1.5
—
—
—
0
0
8
41
1.99
1.10
3.8
1.6
—
—
—
0
0
19
121
1.62
1.09
1.7
1.5
—
—
—
0
0
52
409
1.35
1.07
1.5
1.5
16.98
21.20
nmol/l
1.87
44
349
195
1852
1.41
0.94
5.3
4.7
2.70
2.76
mmol/l
0.38
180
1717
10
55
1.86
0.93
8.4
4.1
1.57
1.54
mg/l
—
10
50
51
411
1.31
0.90
3.2
2.9
0.57
0.72
ug/l
1.41
30
268
8
44
1.85
0.87
1.1
1.5
—
—
—
0
0
52
423
1.30
0.86
2.8
2.0
3.24
3.06
mg/l
0.18
43
371
6
32
1.90
0.82
5.2
3.2
55.00
60.50
%
—
6
32
19
267
0.68
0.81
1.1
1.7
1.45
1.52
%
0.18
13
234
191
1819
1.34
0.80
4.9
4.3
4.58
4.63
mmol/l
0.27
181
1696
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
5
24
2.11
0.75
1.4
1.2
—
—
—
0
0
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
5
24
2.11
0.75
1.0
1.4
—
—
—
0
0
83
727
1.23
0.73
2.9
2.3
70.85
77.62
nmol/l
1.35
75
649
5
25
2.02
0.73
1.0
1.4
—
—
—
0
0
10
61
1.67
0.69
2.7
2.4
32.60
81.47
ug/min
—
5
33
189
1808
1.29
0.67
4.9
4.3
1.37
1.44
mmol/l
1.40
175
1677
7
44
1.61
0.65
1.0
1.2
—
—
—
0
0
5
29
1.74
0.64
2.6
4.2
—
1265.40
—
0
5
0
21
0.00
0.60
0.0
1.2
—
143.04
—
0
21
15
106
1.44
0.59
1.2
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
0
23
0.00
0.58
0.0
1.5
—
—
—
0
0
9
63
1.45
0.53
2.1
1.1
9.84
10.14
g/l
—
9
58
18
135
1.36
0.53
1.7
2.6
64.94
66.61
g/l
0.39
18
126
63
559
1.18
0.47
4.0
4.1
20.32
21.70
%
0.38
24
257
7
50
1.41
0.45
1.6
1.2
—
—
—
0
0
19
148
1.31
0.45
4.0
2.9
54.00
65.41
ml/min/173m2
0.66
11
69
5
33
1.53
0.41
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
43
375
1.18
0.40
2.1
1.8
354.11
450.27
pmol/l
1.87
34
322
17
134
1.29
0.38
4.8
3.0
4.34
4.46
kpa
0.11
17
128
9
71
1.28
0.36
2.1
1.2
—
—
—
0
0
180
1745
1.16
0.35
4.4
3.9
1.44
1.27
mmol/l
1.87
165
1615
6
43
1.41
0.35
1.5
1.2
—
—
—
0
0
6
43
1.41
0.35
1.2
1.5
—
—
—
0
0
6
44
1.37
0.34
1.3
1.3
—
—
—
0
0
7
54
1.31
0.30
1.7
1.5
—
—
—
0
0
7
55
1.28
0.30
1.6
3.1
—
—
—
0
0
8
107
0.74
0.29
1.1
1.3
—
—
—
0
0
16
194
0.81
0.29
7.1
7.1
—
—
—
0
0
18
149
1.23
0.29
2.0
2.5
14.69
7.62
ug/l
0.33
13
136
8
66
1.22
0.27
1.5
1.9
—
—
—
0
0
24
208
1.17
0.25
2.5
2.0
—
—
—
0
0
26
228
1.16
0.24
2.5
2.2
—
—
—
0
0
29
257
1.15
0.23
1.3
1.4
—
—
—
0
0
5
39
1.29
0.23
1.4
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.8
—
112.00
—
0
11
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
14
118
1.20
0.19
13.5
6.4
23.34
24.30
mmol/l
0.32
14
111
6
53
1.14
0.19
1.0
1.2
—
—
—
0
0
7
60
1.17
0.18
1.0
2.3
—
—
—
0
0
7
60
1.17
0.18
1.6
1.7
—
—
—
0
0
7
62
1.13
0.17
1.7
1.6
—
—
—
0
0
7
63
1.11
0.17
1.6
1.8
—
—
—
0
0
9
78
1.16
0.15
1.4
2.2
38.56
39.84
u/l
—
9
73
84
806
1.07
0.15
3.8
2.7
117.37
121.66
ug/l
0.10
79
752
8
96
0.83
0.14
1.5
1.5
—
—
—
0
0
14
123
1.15
0.13
1.1
1.2
146.48
121.02
iu/ml
—
5
42
14
124
1.14
0.11
1.3
1.2
—
25.56
—
0
8
5
44
1.14
0.10
1.2
1.7
—
—
—
0
0
5
48
1.04
0.09
1.0
3.5
—
4.26
—
0
5
7
84
0.83
0.07
2.1
3.1
48.43
2156.13
u/ml
—
7
71
32
308
1.05
0.04
2.5
1.6
1064.55
1261.25
nmol/l
0.64
27
245
19
200
0.95
0.04
2.4
4.0
229.47
244.43
u/l
0.48
19
193
17
178
0.95
0.02
2.0
1.7
—
—
—
0
0
11
115
0.95
0.00
2.5
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
46.22
—
0
9
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
—
—
0
0
6
59
1.02
0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
7.89
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
9
95
0.95
-0.00
2.6
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
7
0.00
-0.00
0.0
1.0
—
128.00
—
0
7
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
8.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint N14_RENALCOLNAS and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| N14_RENALCOLNAS | 0.872 [0.68, 1.11] | 0.268 |
| Birth year | 0.99 [0.98, 1.0] | 0.039 |
During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 836 males with N14_RENALCOLNAS died.
Mortality risk
Mortality risk for people of age
years, who have N14_RENALCOLNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.145% |
| 5 | No data | 1.102% |
| 10 | No data | 2.804% |
| 15 | No data | 5.38% |
| 20 | No data | 9.006% |
Relationships between endpoints
↥Index endpoint: N14_RENALCOLNAS – Unspecified renal colic
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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