vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1394 |
4. Check minimum number of eventsNone |
1394 |
5. Include endpointsNone |
1394 |
6. Filter based on genotype QC (FinnGen only) |
1394 |
Control definitions (FinnGen only)
- Control exclude
- H8_INNER
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other/unspecified disorders of vestibular function
based on the number of shared cases.
Similar with more cases:
- Disorders of vestibular function (Vertigo)
- Diseases of inner ear
- Diseases of the ear and mastoid process
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10780 | 6802 | 3882 |
| Only index persons | 9261 | 5920 | 3341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.16 | 0.19 | 0.11 |
| Only index persons | 0.19 | 0.22 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 64.51 | 66.08 | 61.73 |
| Only index persons | 62.36 | 63.66 | 60.06 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1394 | 882 | 512 |
| Unadjusted period prevalence (%) | 0.27 | 0.30 | 0.23 |
| Median age at first event (years) | 60.88 | 60.30 | 61.86 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1220
- Matched controls
- 12200
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
1432.0
323.0
845
19
R42
ICD-10 Finland
Dizziness and giddiness
8.8
247.2
696
1604
H81.8
ICD-10 Finland
Other disorders of vestibular function
1315.9
229.8
217
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
12.4
153.3
295
305
H81.0
ICD-10 Finland
Ménière disease
123.4
133.3
142
13
3868X
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other disorders of labyrinth
+∞
116.5
110
*
N07CA01
ATC
betahistine; oral
8.3
111.0
269
404
H81.2
ICD-10 Finland
Vestibular neuronitis
224.7
101.1
103
5
H81.3
ICD-10 Finland
Other peripheral vertigo
34.7
82.8
108
34
AA1AD
NOMESCO Finland
CT of head and brain
3.5
76.8
478
1906
3869X
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Unspecified vertiginous syndromes and labyrinthine disorders
+∞
64.1
61
*
N17
ICPC
Vertigo/dizziness
4.1
59.6
264
769
DFF00
NOMESCO Finland
Pure tone audiometry
4.4
52.1
206
533
DFF59
NOMESCO Finland
Other assessment of balance
32.0
46.2
61
20
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.2
41.6
252
920
G44.2
ICD-10 Finland
Tension-type headache
2.9
32.1
214
822
UDC00
NOMESCO Finland
Ear microscopy
3.6
28.5
135
402
R53
ICD-10 Finland
Malaise and fatigue
2.2
25.8
306
1591
R51.80
ICD-10 Finland
Headache
2.5
24.6
211
929
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
4.8
23.7
81
178
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
53.0
22.1
26
5
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
7.3
21.2
51
72
A02BC02
ATC
pantoprazole; systemic
1.8
20.1
801
6306
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
2.2
20.1
243
1260
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
20.0
366
2235
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
19.8
556
3919
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
19.4
433
2828
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.8
18.1
119
447
H81.4
ICD-10 Finland
Vertigo of central origin
21.2
17.3
25
12
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
16.9
230
1243
M79.6
ICD-10 Finland
Pain in limb
1.7
16.8
435
2945
R11
ICD-10 Finland
Nausea and vomiting
2.7
16.7
121
481
N05AB04
ATC
prochlorperazine; systemic, rectal
4.5
16.6
59
136
R07.3
ICD-10 Finland
Other chest pain
2.5
16.0
132
566
N02BE01
ATC
paracetamol; systemic, rectal
1.9
15.8
1045
9220
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
15.6
213
1152
DFF50
NOMESCO Finland
Electronystagmography
162.0
15.5
16
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
15.2
358
2340
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.2
15.0
158
762
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
14.8
266
1592
M79.1
ICD-10 Finland
Myalgia
2.2
14.7
161
791
N03AX12
ATC
gabapentin; oral
2.0
14.7
201
1086
H82
ICPC
Vertiginous syndrome
6.2
14.6
39
65
B01AC04
ATC
clopidogrel; oral
2.0
14.2
212
1182
R06.0
ICD-10 Finland
Dyspnoea
1.7
13.7
316
2042
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
4.9
13.2
43
91
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
7.7
13.2
30
40
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
13.1
757
6206
S06.0
ICD-10 Finland
Concussion
2.2
12.9
131
622
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
12.8
435
3124
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
6.1
12.8
34
57
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.3
12.6
123
573
H02AB06
ATC
prednisolone; systemic
1.6
12.5
544
4140
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.5
12.4
95
391
M03BX02
ATC
tizanidine; oral
1.5
12.3
685
5525
N03AX16
ATC
pregabalin; oral
1.7
12.2
282
1817
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
11.9
254
1591
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
11.9
208
1223
C07AB07
ATC
bisoprolol; oral
1.5
11.9
590
4615
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.9
11.9
191
1092
R55
ICD-10 Finland
Syncope and collapse
2.0
11.8
151
792
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
11.7
352
2434
N01
ICPC
Headache
2.3
11.6
112
517
L01
ICPC
Neck symptom/complaint
2.0
11.6
161
872
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
11.5
369
2592
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
11.5
252
1593
N06AX11
ATC
mirtazapine; oral
1.6
11.4
372
2624
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
11.4
234
1449
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
11.2
84
339
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
11.0
176
1001
A28
ICPC
Limited function/disability NOS
1.8
10.7
199
1193
G43.9
ICD-10 Finland
Migraine, unspecified
2.9
10.7
63
223
R03AC02
ATC
salbutamol; inhalant
1.5
10.6
583
4625
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
10.5
584
4642
DC1AD
NOMESCO Finland
Temporalbone CT
7.5
10.2
23
31
L28
ICPC
Limited function/disability (L)
1.8
10.2
203
1242
C10AA05
ATC
atorvastatin; oral
1.5
10.2
456
3445
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
10.2
109
528
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.2
10.1
104
496
N02AX02
ATC
tramadol; systemic, rectal
1.5
10.0
485
3730
A02BC01
ATC
omeprazole; systemic
1.6
9.9
337
2388
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
9.8
87
387
M54.5
ICD-10 Finland
Low back pain
1.5
9.8
356
2563
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
9.8
209
1308
A04
ICPC
Weakness/tiredness general
1.8
9.8
163
942
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
9.7
228
1463
N06AX21
ATC
duloxetine; oral
2.0
9.7
127
670
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
9.7
205
1279
H93.1
ICD-10 Finland
Tinnitus
2.4
9.6
81
352
UJF32
NOMESCO Finland
Coloscopy
1.6
9.6
306
2131
A01
ICPC
Pain general/multiple sites
2.2
9.5
100
480
A02BC03
ATC
lansoprazole; oral
1.5
9.5
357
2586
J01AA02
ATC
doxycycline; systemic
1.5
9.4
898
7905
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.6
9.4
31
68
H80.9
ICD-10 Finland
Otosclerosis, unspecified
100.8
9.4
10
*
3861A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other and unspecified peripheral vertigo
+∞
9.4
9
*
D09
ICPC
Nausea
3.0
9.4
54
188
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.0
9.3
114
585
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.1
9.3
101
495
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
9.2
517
4075
M54.2
ICD-10 Finland
Cervicalgia
2.3
9.2
86
393
A02BC05
ATC
esomeprazole; systemic
1.5
9.1
461
3558
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.0
9.0
116
608
H91.9
ICD-10 Finland
Hearing loss, unspecified
2.8
8.9
56
205
N06AB10
ATC
escitalopram; oral
1.7
8.8
209
1341
TAB00
NOMESCO Finland
Lumbar puncture
2.8
8.8
55
200
R52.9
ICD-10 Finland
Pain, unspecified
2.1
8.8
106
540
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
8.8
209
1345
J01FA06
ATC
roxithromycin; oral
1.5
8.8
455
3517
R50.9
ICD-10 Finland
Fever, unspecified
1.8
8.8
158
936
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
8.7
551
4433
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
8.7
492
3873
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.2
8.7
92
444
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
2.2
8.7
90
433
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.9
8.6
51
182
N06AB04
ATC
citalopram; systemic
1.6
8.6
242
1626
L17
ICPC
Foot/toe symptom/complaint
1.6
8.6
282
1970
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
8.5
253
1728
DAX00
NOMESCO Finland
Adjustment or review of hearing aid
2.5
8.4
62
252
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
8.3
426
3276
K02.1
ICD-10 Finland
Caries of dentine
1.4
8.3
574
4681
R4110
NOMESCO Finland
Physiotherapy
1.5
8.3
307
2206
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
8.2
282
1990
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.9
8.2
127
712
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
3.1
8.2
43
142
R05
ICD-10 Finland
Cough
1.6
8.2
212
1391
N05CF01
ATC
zopiclone; oral
1.5
8.2
378
2844
DFF15
NOMESCO Finland
Speech audiometry
2.5
8.2
60
243
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
8.1
176
1101
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
8.0
581
4766
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
8.0
105
557
H81
ICD-10 Finland
Disorders of vestibular function
22.2
8.0
11
5
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
7.9
137
802
M25.5
ICD-10 Finland
Pain in joint
1.5
7.8
303
2194
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
7.7
450
3538
A11
ICPC
Chest pain NOS
2.0
7.7
96
496
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
7.6
409
3163
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.0
7.6
95
493
WX892
NOMESCO Finland
Monitored bed care
2.0
7.6
93
480
N05AH04
ATC
quetiapine; oral
1.7
7.5
166
1042
L29
ICPC
Musculoskeletal sympt/complt other
2.0
7.5
90
461
R01AD09
ATC
mometasone; nasal
1.4
7.4
460
3654
I20.09
ICD-10 Finland
Unstable angina
2.2
7.4
74
352
G04CA02
ATC
tamsulosin; oral
1.6
7.3
223
1527
3860A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Ménière's disease
+∞
7.3
7
*
N06AX16
ATC
venlafaxine; oral
1.8
7.3
138
828
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.2
526
4296
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.3
7.2
62
272
XF404
NOMESCO Finland
Ambulatory ECG
1.9
7.2
108
602
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
7.2
210
1423
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
7.1
194
1290
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.0
7.1
88
458
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
7.1
75
366
H29
ICPC
Ear symptom/complaint other
1.8
7.1
116
665
KMAK
NOMESCO Finland
NA
1.4
7.0
520
4252
P03
ICPC
Feeling depressed
2.0
7.0
85
438
J01CA04
ATC
amoxicillin; systemic
1.4
7.0
878
7855
J01DA01
ATC
[U] cefalexin; systemic
1.4
7.0
703
6052
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
7.0
102
562
J01MA02
ATC
ciprofloxacin; systemic
1.4
6.9
436
3458
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
6.9
284
2073
I95.1
ICD-10 Finland
Orthostatic hypotension
2.6
6.9
48
190
WX110
NOMESCO Finland
Local anesthesy
1.4
6.9
725
6285
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
6.9
253
1805
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.2
6.8
24
58
R03DC03
ATC
montelukast; oral
1.6
6.8
167
1082
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
6.8
176
1157
A02BA02
ATC
ranitidine; systemic
1.5
6.8
231
1622
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
2.8
6.7
41
151
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
6.7
74
366
M54.6
ICD-10 Finland
Pain in thoracic spine
2.1
6.7
74
367
M48.0
ICD-10 Finland
Spinal stenosis
1.7
6.7
146
916
N05BA01
ATC
diazepam; systemic, rectal
1.7
6.7
152
966
Z71.8
ICD-10 Finland
Other specified counselling
1.5
6.7
239
1697
L03
ICPC
Low back symptom/complaint
1.5
6.6
248
1776
G43.8
ICD-10 Finland
Other migraine
5.2
6.6
19
37
R06AE53
ATC
cyclizine, combinations; systemic
5.2
6.6
19
37
K24
ICPC
Fear of heart disease
3.0
6.6
35
118
TDA90
NOMESCO Finland
Removal wax from ear
4.2
6.6
23
55
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
6.6
383
2988
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.8
6.5
20
42
P01AB01
ATC
metronidazole; oral, rectal
1.4
6.5
419
3328
J01FA10
ATC
azithromycin; systemic
1.4
6.5
591
4978
Z01.2
ICD-10 Finland
Dental examination
1.4
6.5
414
3287
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.4
6.5
52
222
K30
ICD-10 Finland
Functional dyspepsia
1.8
6.5
116
687
R13
ICD-10 Finland
Dysphagia
2.1
6.5
74
372
K07.60
ICD-10 Finland
Snapping jaw
2.5
6.5
49
204
C01DA14
ATC
isosorbide mononitrate; oral
1.5
6.4
198
1358
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.8
6.4
112
657
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.4
477
3883
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.0
6.4
80
419
H02
ICPC
Hearing complaint
1.7
6.4
133
823
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
6.3
278
2055
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.8
6.3
37
133
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
6.3
126
774
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
3.5
6.2
27
79
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
6.2
112
664
G47.3
ICD-10 Finland
Sleep apnoea
1.5
6.2
205
1426
K89
ICPC
Transient cerebral ischaemia
5.1
6.2
18
36
N06AA09
ATC
amitriptyline; systemic
1.7
6.2
120
726
L08
ICPC
Shoulder symptom/complaint
1.5
6.2
191
1310
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.5
6.2
45
185
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
6.2
233
1670
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.0
6.2
74
380
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.7
6.1
40
153
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.2
6.1
58
270
D02
ICPC
Abdominal pain epigastric
2.1
6.1
67
330
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
6.1
290
2177
N05BA04
ATC
oxazepam; oral
1.4
6.1
271
2009
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.5
6.1
258
1893
C09CA03
ATC
valsartan; oral
1.8
6.1
102
591
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.1
198
1375
M01AH05
ATC
etoricoxib; oral
1.3
6.0
610
5203
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.4
6.0
49
210
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
6.0
105
614
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
598
3547
2.20
43.55
2.4
2.1
163.7
244.2
u/l
1.31
576
3323
361
1780
2.39
40.47
2.0
2.0
28.6
29.7
s
3.67
350
1727
430
2289
2.27
40.27
4.4
3.9
366.4
373.8
ng/l
0.02
341
1865
940
6784
2.18
39.83
5.1
4.7
6.7
6.8
mmol/l
0.79
899
6342
763
5330
1.95
32.31
6.1
5.9
1.2
1.2
mmol/l
0.67
701
4798
675
4542
1.94
31.78
5.0
3.7
44.7
48.6
ng/l
0.09
470
3268
815
5890
1.92
30.42
7.3
6.7
1.2
1.2
mmol/l
1.84
699
4951
1061
8458
2.07
28.87
4.9
4.1
12.8
13.2
mm/h
0.35
990
7755
964
7667
1.83
23.39
6.3
4.8
548.9
2620.5
e6/l
1.35
16
116
1278
11239
2.65
23.37
20.8
15.0
21.1
24.9
mg/l
4.31
1076
8999
531
3654
1.73
20.52
3.4
3.0
1349.3
1541.6
ng/l
0.57
463
3133
690
5140
1.68
19.57
4.3
4.6
35.6
35.1
g/l
1.51
629
4755
664
4916
1.67
19.13
2.3
2.0
95.2
95.0
pmol/l
0.03
325
2478
431
2855
1.74
18.73
1.6
1.6
21.8
20.5
nmol/l
0.82
376
2394
778
6064
1.64
17.81
5.5
6.1
11.3
11.5
umol/l
0.19
741
5754
1052
8891
1.75
17.42
8.1
7.4
77.8
79.3
u/l
0.50
1001
8320
878
7086
1.65
17.21
3.4
3.1
47.6
51.1
u/l
0.58
814
6551
1292
11710
2.41
16.97
23.7
17.7
4.0
4.0
mmol/l
1.57
1268
11367
510
3618
1.65
16.73
2.8
2.5
57.0
57.0
u/l
0.00
464
3326
1288
11679
2.35
16.54
23.6
17.6
139.5
139.6
mmol/l
0.35
1268
11355
1027
8683
1.69
16.28
4.7
4.1
14.9
14.9
pmol/l
0.04
948
7826
313
1978
1.75
15.67
2.0
1.8
—
—
—
0
0
794
6388
1.56
14.61
3.2
2.8
—
—
—
0
0
1171
10374
1.81
14.48
5.9
4.9
1.9
2.1
mu/l
0.99
1087
9396
371
2510
1.65
14.24
2.0
1.6
1.1
1.2
mg/l
0.27
284
1938
230
1371
1.81
13.91
5.2
7.4
1.0
1.2
mmol/l
0.45
174
1078
137
686
2.11
13.83
2.7
2.5
22.9
16.3
au/ml
—
9
33
228
1376
1.79
13.19
5.2
7.4
5.0
5.1
kpa
1.54
222
1315
228
1376
1.79
13.19
5.2
7.4
12.2
12.0
kpa
0.14
223
1317
66
245
2.78
12.93
1.3
1.4
89.8
15.3
e6/l
0.60
50
193
66
245
2.78
12.93
1.3
1.5
3213.1
1066.6
e6/l
0.32
50
203
801
6563
1.52
12.76
9.3
8.8
4.3
4.1
e9/l
1.11
686
5719
612
4789
1.50
11.86
2.6
2.2
78.8
78.7
nmol/l
0.05
545
4251
1161
10415
1.69
11.79
6.7
6.0
40.5
40.2
mmol/mol
0.47
1079
9562
207
1255
1.76
11.71
2.3
2.1
137.0
124.4
ug/g
0.19
161
975
281
1853
1.65
11.65
3.6
2.9
1.8
2.6
e6/l
1.70
147
1017
484
3622
1.52
11.57
3.2
3.1
31.2
33.9
u/l
0.76
453
3435
612
4819
1.48
11.34
3.1
2.7
113.1
128.3
ug/l
1.34
563
4391
337
2340
1.58
11.26
1.3
1.2
1.1
1.6
u/ml
0.53
68
601
295
1991
1.61
11.09
3.3
2.8
1.1
1.2
e6/l
0.19
160
1150
222
1397
1.70
10.96
1.9
1.7
—
—
—
0
0
221
1398
1.69
10.69
1.9
1.8
—
—
—
0
0
281
1890
1.61
10.68
1.4
1.2
25.2
33.6
iu/ml
0.65
79
598
177
1070
1.75
10.06
2.3
2.2
30.4
37.4
u/l
1.43
156
908
686
5614
1.44
9.92
4.8
3.9
0.0
0.0
estimate
0.00
103
1038
205
1299
1.68
9.81
3.5
3.9
239.9
254.7
u/l
0.78
188
1224
531
4154
1.45
9.75
2.8
3.4
2.4
2.4
mmol/l
0.59
440
3595
1279
11925
1.88
9.66
12.6
10.5
24.7
25.3
u/l
0.67
1241
11467
685
5637
1.42
9.43
6.6
5.4
0.0
0.0
estimate
0.50
105
1047
432
3274
1.46
9.27
3.7
3.1
0.4
0.5
e6/l
0.15
315
2510
689
5697
1.41
9.12
4.9
4.0
0.0
0.0
estimate
0.50
102
1017
403
3041
1.46
8.75
2.5
2.2
2.7
3.1
mg/l
4.23
354
2564
1112
10087
1.51
8.47
22.1
16.3
39.2
39.2
%
0.06
758
6901
170
1068
1.67
8.37
3.1
3.0
217.9
234.1
ng/l
0.10
159
977
273
1924
1.52
8.27
2.7
3.1
0.8
0.8
mmol/l
0.85
255
1794
323
2370
1.47
8.01
1.8
1.8
1067.9
1205.7
nmol/l
1.97
247
1750
232
1590
1.55
7.97
33.6
26.5
1.4
1.4
inr
0.05
30
193
652
5423
1.38
7.92
4.1
4.0
—
—
—
0
0
1309
12402
1.91
7.83
30.0
22.1
247.4
250.1
e9/l
0.83
1287
12069
126
743
1.76
7.79
1.8
1.6
—
—
—
0
0
142
867
1.71
7.77
1.8
1.6
—
—
—
0
0
1309
12408
1.90
7.73
30.0
22.1
4.4
4.4
e12/l
0.24
1283
12030
1309
12409
1.90
7.71
30.1
22.1
7.0
6.8
e9/l
1.75
1282
12033
257
1813
1.51
7.71
1.4
1.2
25.8
13.1
u/ml
0.29
86
665
1309
12411
1.90
7.68
30.1
22.2
133.6
133.6
g/l
0.02
1295
12201
196
1304
1.59
7.65
2.1
2.5
9.2
8.6
umol/l
0.09
173
1128
128
763
1.75
7.63
4.8
7.3
24.4
24.5
mmol/l
0.14
123
713
1185
10965
1.54
7.51
5.3
4.7
6.0
6.0
mmol/l
0.42
1095
9877
75
378
2.04
7.49
1.7
2.3
37.5
37.5
g/l
0.00
64
327
203
1369
1.57
7.47
2.3
2.4
2.0
1.8
%
0.97
184
1198
84
442
1.96
7.44
1.9
2.5
9.8
10.4
g/l
0.65
70
378
1026
9247
1.41
7.35
24.4
18.3
13.7
13.8
%
0.34
1012
9026
72
360
2.05
7.35
1.7
2.3
0.1
0.0
g/l
0.49
67
329
84
444
1.95
7.34
1.8
2.5
3.1
3.2
g/l
0.07
66
351
88
473
1.92
7.33
1.9
2.4
3.7
3.7
g/l
0.25
65
345
226
1568
1.53
7.31
5.4
5.3
1.0
1.0
mmol/l
0.19
204
1435
88
474
1.91
7.28
1.9
2.4
7.5
7.5
g/l
0.06
66
360
88
474
1.91
7.28
1.9
2.4
—
—
—
0
0
334
2517
1.43
7.09
5.3
4.3
1.0
1.0
kg/l
0.60
53
374
1146
10566
1.48
7.04
18.4
14.0
78.4
77.9
ml/min/173m2
0.35
948
8727
23
66
3.53
7.00
1.0
1.0
—
—
—
0
0
225
1576
1.51
6.94
2.4
2.5
23.0
22.5
%
0.17
188
1341
238
1689
1.49
6.89
2.4
2.4
2.3
2.3
g/l
0.14
224
1557
254
1828
1.48
6.86
2.5
2.4
13.3
12.7
umol/l
0.52
238
1678
161
1049
1.60
6.85
1.8
2.0
363.8
379.4
nmol/l
0.48
148
954
65
322
2.07
6.82
1.6
1.7
—
—
—
0
0
341
2597
1.41
6.79
1.8
1.7
36268042.0
16358015.4
pmol/l
0.32
284
2103
29
100
2.94
6.60
1.1
1.1
—
—
—
0
0
77
412
1.92
6.52
1.9
2.5
0.4
1.3
g/l
1.76
68
361
67
342
2.01
6.50
1.7
2.4
0.0
0.0
g/l
0.00
62
312
329
2510
1.41
6.45
2.6
2.6
5.9
6.2
e6/l
0.17
283
2210
28
96
2.96
6.45
1.1
1.1
—
—
—
0
0
152
994
1.59
6.37
1.9
2.9
65.8
66.5
g/l
0.73
128
902
157
1038
1.58
6.28
6.0
6.7
1.2
1.4
mmol/l
2.41
149
995
146
949
1.60
6.27
3.7
3.6
91.2
90.4
ng/l
0.03
128
815
40
170
2.39
6.09
1.2
1.1
—
—
—
0
0
29
105
2.80
6.07
1.3
1.7
—
—
—
0
0
17
44
3.90
5.99
1.1
2.2
—
—
—
0
0
81
457
1.82
5.85
1.7
1.9
39.0
39.1
u/l
0.01
72
401
111
691
1.66
5.68
4.1
3.7
1.6
1.9
mmol/l
0.40
88
518
32
128
2.54
5.56
1.3
1.4
300.4
291.9
pmol/l
0.06
27
98
66
355
1.90
5.54
1.5
1.2
—
—
—
0
0
114
720
1.64
5.52
1.7
1.5
—
—
—
0
0
221
1613
1.44
5.49
1.5
1.5
—
—
—
0
0
373
2972
1.35
5.49
2.5
2.6
5949.0
6923.5
umol/l
0.14
309
2547
1136
10582
1.40
5.47
4.3
4.0
1.3
1.3
mmol/l
1.59
1043
9549
28
107
2.65
5.33
1.1
1.1
—
—
—
0
0
10
19
5.29
5.04
1.1
1.1
—
—
—
0
0
1195
11269
1.42
5.01
5.7
5.0
2.6
2.7
mmol/l
1.94
1106
10254
113
732
1.59
4.95
4.1
3.7
5.3
5.2
kpa
0.55
103
677
87
531
1.68
4.83
1.6
1.9
1.6
1.5
g/l
0.53
73
463
112
730
1.58
4.79
7.3
8.9
93.8
93.8
%
0.01
112
725
11
24
4.61
4.78
1.5
1.1
0.4
0.4
ug/l
—
5
13
1164
10952
1.38
4.73
4.9
4.4
1.4
1.5
mmol/l
5.09
1074
9951
1171
11047
1.38
4.52
5.0
4.5
4.6
4.6
mmol/l
1.79
1090
10109
297
2349
1.34
4.50
2.8
3.0
2.5
2.5
mmol/l
0.21
249
2053
156
1114
1.45
4.35
3.8
3.5
2.3
2.0
mmol/l
0.48
132
901
42
211
2.02
4.35
1.3
1.2
41.3
33.9
u/ml
—
5
16
347
2825
1.30
4.26
2.4
2.3
—
—
—
0
0
18
62
2.93
4.18
1.1
1.0
1.1
1.1
u/l
—
7
33
18
63
2.88
4.07
1.2
1.1
9.8
10.9
iu/ml
—
6
16
20
75
2.69
4.00
1.3
1.4
—
335.6
—
0
9
425
3576
1.27
3.99
3.0
3.1
7.2
7.2
mmol/l
0.12
342
2982
99
656
1.55
3.98
3.2
3.3
4.3
4.5
pmol/l
1.44
85
573
57
328
1.77
3.95
1.5
1.5
1.2
1.2
g/l
0.00
51
306
46
252
1.85
3.75
1.5
2.1
135.0
127.7
g/l
1.17
34
185
44
240
1.86
3.64
2.8
1.9
5287.6
3815.2
u/l
0.16
13
99
30
143
2.12
3.60
1.6
1.4
—
—
—
0
0
84
550
1.56
3.58
2.9
3.9
24.7
24.2
mmol/l
0.70
78
494
499
4340
1.23
3.40
5.5
4.2
—
—
—
0
0
373
3148
1.25
3.33
4.9
5.0
2.7
3.0
ug/l
0.18
338
2806
45
257
1.78
3.24
1.3
1.3
—
—
—
0
0
45
257
1.78
3.24
1.3
1.3
—
—
—
0
0
145
1079
1.38
3.24
2.6
2.4
6.4
7.2
ug/l
0.14
118
945
9
19
4.76
3.24
1.2
1.2
—
—
—
0
0
45
258
1.77
3.21
1.3
1.1
—
—
—
0
0
61
382
1.62
3.16
1.3
1.2
0.3
1.1
u/ml
—
8
29
354
2988
1.25
3.14
1.7
1.6
1.3
1.4
mmol/l
0.07
307
2501
35
187
1.89
3.12
1.1
1.2
—
—
—
0
0
41
234
1.77
2.99
1.7
1.6
—
—
—
0
0
31
162
1.93
2.96
1.8
1.6
—
—
—
0
0
43
251
1.74
2.91
1.6
1.4
—
—
—
0
0
75
505
1.51
2.87
1.1
1.0
—
—
—
0
0
46
276
1.69
2.83
1.4
1.2
3.4
12.8
u/ml
—
5
47
59
378
1.59
2.82
1.4
1.3
32.0
30.7
iu/l
0.11
54
324
417
3621
1.22
2.79
3.8
3.9
10.0
9.2
mg/mmol
0.10
241
2242
16
66
2.44
2.71
1.8
2.0
—
—
—
0
0
50
311
1.63
2.70
2.4
2.1
177.8
192.2
%
0.57
45
297
301
2535
1.24
2.70
4.1
4.3
21.8
21.4
%
0.20
134
1253
54
343
1.60
2.68
1.3
1.1
—
—
—
0
0
179
1419
1.30
2.65
4.8
4.5
32.0
32.7
%
0.28
120
932
7
15
4.68
2.60
1.7
1.5
—
—
—
0
0
27
142
1.92
2.56
1.8
1.4
—
—
—
0
0
20
94
2.14
2.55
1.0
1.3
—
—
—
0
0
53
340
1.58
2.54
1.3
1.1
—
—
—
0
0
53
340
1.58
2.54
1.6
1.4
262.7
283.9
ug/g
0.28
30
194
33
187
1.78
2.50
6.0
5.4
390.1
311.9
iu/ml
—
7
19
142
1105
1.32
2.42
2.0
2.1
0.2
0.2
g/l
1.00
134
1022
50
321
1.58
2.41
2.1
1.8
—
—
—
0
0
69
476
1.47
2.39
2.1
1.9
—
—
—
0
0
102
756
1.38
2.39
1.8
1.8
—
—
—
0
0
90
653
1.40
2.39
2.3
2.2
11.6
13.1
nmol/l
0.76
78
569
134
1037
1.32
2.37
7.0
7.1
10.3
10.3
mmol/l
0.02
121
986
18
85
2.13
2.29
1.9
1.4
27.5
19.2
u/ml
—
6
14
13
53
2.47
2.28
1.2
1.2
—
—
—
0
0
74
524
1.44
2.26
1.3
1.3
—
—
—
0
0
48
313
1.55
2.19
1.5
1.6
35.2
19.1
iu/ml
—
10
63
6
14
4.30
2.15
1.5
1.0
—
—
—
0
0
29
167
1.75
2.12
1.2
1.2
1.3
2.2
u/ml
—
10
50
22
116
1.91
2.11
1.6
1.5
—
—
—
0
0
27
153
1.78
2.09
1.1
1.1
—
—
—
0
0
7
20
3.51
2.05
1.0
1.3
—
—
—
0
0
30
177
1.71
2.03
1.1
1.2
230.6
272.1
u/ml
0.44
14
101
93
702
1.35
1.98
1.2
1.2
67.9
140.1
iu/ml
2.43
30
271
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
13
57
2.29
1.98
1.1
1.2
—
—
—
0
0
25
141
1.79
1.97
1.8
1.4
—
—
—
0
0
67
480
1.42
1.96
1.7
1.9
0.6
1.9
ug/l
1.35
58
420
143
1149
1.27
1.95
1.7
1.8
1.5
1.5
%
0.14
118
990
25
142
1.77
1.93
1.8
1.4
—
—
—
0
0
22
120
1.85
1.93
1.5
1.6
—
—
—
0
0
46
307
1.52
1.92
1.4
1.5
—
—
—
0
0
37
235
1.59
1.91
2.3
2.3
17.0
15.9
%
0.53
15
121
107
832
1.31
1.88
2.0
2.0
—
—
—
0
0
24
136
1.78
1.88
12.5
7.9
8.1
7.5
mmol/l
0.35
19
113
26
151
1.74
1.87
1.2
1.1
—
—
—
0
0
76
564
1.37
1.82
5.9
3.7
50.8
48.6
%
0.35
76
557
5
12
4.18
1.82
1.0
2.2
—
—
—
0
0
8
29
2.77
1.79
1.0
1.1
—
—
—
0
0
20
109
1.85
1.77
1.5
1.7
—
—
—
0
0
40
265
1.52
1.75
1.5
1.3
—
—
—
0
0
24
140
1.73
1.72
1.9
1.4
—
—
—
0
0
14
68
2.07
1.70
1.1
1.2
—
—
—
0
0
14
68
2.07
1.70
1.1
1.2
—
—
—
0
0
28
172
1.64
1.68
1.2
1.4
108.2
139.7
u/ml
—
5
30
14
69
2.04
1.65
1.1
1.2
—
—
—
0
0
14
69
2.04
1.65
2.4
1.9
11.0
12.8
%
—
8
32
18
98
1.85
1.62
1.1
1.1
—
—
—
0
0
5
134
0.37
1.61
1.4
1.5
—
—
—
0
0
14
70
2.01
1.59
2.0
1.4
—
—
—
0
0
14
70
2.01
1.59
2.0
1.4
—
—
—
0
0
41
281
1.47
1.56
1.2
1.3
—
—
—
0
0
18
101
1.79
1.49
6.1
3.4
61.8
53.9
%
0.61
13
73
340
3048
1.15
1.48
5.8
4.2
0.0
0.0
estimate
1.08
105
1007
23
140
1.65
1.45
1.9
1.4
—
—
—
0
0
7
28
2.51
1.45
1.3
1.2
—
—
—
0
0
14
73
1.93
1.44
1.2
2.1
—
—
—
0
0
19
314
0.60
1.42
1.4
1.4
—
—
—
0
0
23
141
1.64
1.42
1.9
1.4
—
—
—
0
0
26
165
1.59
1.41
1.3
1.2
6.6
5.8
u/ml
0.07
11
72
10
46
2.18
1.40
1.9
1.7
—
—
—
0
0
10
46
2.18
1.40
1.9
1.7
—
—
—
0
0
10
46
2.18
1.40
1.9
1.7
—
—
—
0
0
58
433
1.35
1.40
2.0
1.8
—
—
—
0
0
12
60
2.01
1.38
1.7
1.5
—
—
—
0
0
12
60
2.01
1.38
1.8
1.5
—
—
—
0
0
12
60
2.01
1.38
1.8
1.5
—
—
—
0
0
12
60
2.01
1.38
1.8
1.5
—
—
—
0
0
6
23
2.62
1.37
1.2
1.2
—
—
—
0
0
77
603
1.29
1.35
4.7
3.1
25.8
25.3
mmol/l
0.66
77
585
16
90
1.79
1.33
1.2
1.1
0.1
1.2
u/ml
0.62
11
47
11
54
2.05
1.33
1.1
1.1
—
—
—
0
0
152
1289
1.20
1.31
2.7
4.0
70.0
21.1
ug/l
0.38
114
1067
20
121
1.66
1.31
1.4
1.3
7.3
7.6
mmol/l
0.09
11
85
8
36
2.23
1.24
1.1
1.1
—
—
—
0
0
10
49
2.05
1.22
1.2
1.3
—
—
—
0
0
5
19
2.64
1.21
1.0
1.2
—
—
—
0
0
8
37
2.17
1.21
1.0
2.1
—
74092.3
—
0
6
6
26
2.31
1.18
1.3
1.2
—
—
—
0
0
6
26
2.31
1.18
1.0
1.1
—
—
—
0
0
11
57
1.94
1.17
1.0
1.0
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
64
809
0.78
1.15
1.8
1.7
—
—
—
0
0
51
388
1.33
1.13
2.3
3.5
68.0
46.1
mg/l
0.26
44
317
10
51
1.97
1.11
2.3
1.4
—
—
—
0
0
10
51
1.97
1.11
2.3
1.4
—
—
—
0
0
17
267
0.63
1.08
1.2
1.5
196.2
269.2
pmol/l
0.30
17
261
7
32
2.19
1.08
1.6
1.6
—
—
—
0
0
11
59
1.87
1.07
1.0
1.5
—
—
—
0
0
11
59
1.87
1.07
1.0
1.5
—
—
—
0
0
44
332
1.34
1.04
1.7
2.0
—
—
—
0
0
10
53
1.89
1.01
2.5
2.8
448.5
1051.8
u/ml
—
10
53
44
336
1.32
0.98
2.2
1.8
—
—
—
0
0
28
199
1.42
0.96
1.2
1.3
—
—
—
0
0
35
259
1.36
0.95
4.1
3.9
19.4
25.0
mg/l
0.55
24
163
6
27
2.23
0.93
1.3
1.1
—
—
—
0
0
6
27
2.23
0.93
4.3
1.9
—
—
—
0
0
9
52
1.74
0.92
3.8
4.2
—
—
—
0
0
6
28
2.15
0.91
1.3
1.2
—
—
—
0
0
54
430
1.27
0.90
2.2
1.9
—
—
—
0
0
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
6
29
2.07
0.89
1.3
1.2
—
—
—
0
0
49
386
1.28
0.89
2.4
3.5
35.8
66.3
mg/l
1.12
43
314
5
105
0.47
0.88
1.2
1.5
—
—
—
0
0
13
79
1.65
0.88
1.2
1.7
—
—
—
0
0
16
103
1.56
0.87
1.6
1.5
—
—
—
0
0
16
103
1.56
0.87
1.6
1.5
—
—
—
0
0
16
103
1.56
0.87
1.6
1.5
—
—
—
0
0
8
43
1.87
0.87
1.1
1.3
—
—
—
0
0
8
43
1.87
0.87
1.1
1.1
196.0
203.9
iu/ml
—
8
43
34
256
1.34
0.85
1.2
1.4
—
—
—
0
0
13
80
1.63
0.84
1.0
1.1
—
—
titre
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
50
400
1.26
0.82
3.9
2.7
0.3
0.4
u/ml
0.26
33
227
32
242
1.33
0.79
1.4
1.3
191.2
254.4
miu/ml
0.50
16
108
8
48
1.67
0.78
1.1
1.3
—
—
—
0
0
14
91
1.54
0.75
1.1
1.0
—
—
—
0
0
5
24
2.09
0.74
1.0
1.5
—
—
—
0
0
18
125
1.45
0.72
3.2
2.7
—
—
—
0
0
142
1266
1.14
0.72
3.7
3.5
—
—
—
0
0
7
39
1.80
0.72
1.3
1.0
—
—
—
0
0
7
39
1.80
0.72
1.4
1.3
—
—
—
0
0
9
56
1.61
0.72
1.1
1.3
—
—
—
0
0
13
84
1.55
0.72
1.2
1.1
—
—
—
0
0
13
84
1.55
0.72
1.2
1.1
—
—
—
0
0
13
84
1.55
0.72
1.2
1.1
—
—
—
0
0
13
84
1.55
0.72
1.2
1.1
—
—
—
0
0
13
84
1.55
0.72
1.2
1.1
—
—
—
0
0
21
151
1.40
0.71
1.2
1.1
—
—
—
0
0
5
26
1.93
0.70
1.0
1.0
—
—
—
0
0
5
26
1.93
0.70
1.6
1.2
—
—
—
0
0
49
400
1.23
0.70
2.3
2.9
—
—
—
0
0
36
283
1.28
0.70
2.1
1.7
12113.2
15499.3
e6/l
0.26
25
199
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
10
62
1.62
0.65
1.4
1.1
—
—
—
0
0
29
225
1.30
0.63
1.3
1.3
16.4
10.6
u/l
0.94
23
173
5
30
1.67
0.61
1.2
1.0
1116.2
1643.4
miu/ml
—
5
30
5
30
1.67
0.61
1.0
1.3
—
—
—
0
0
8
51
1.57
0.60
1.1
1.3
—
—
—
0
0
24
183
1.32
0.59
1.8
1.7
—
—
—
0
0
55
465
1.19
0.58
1.8
3.2
22.5
3155.4
u/ml
0.84
41
400
36
293
1.23
0.56
5.2
3.1
1.5
1.6
mmol/l
0.21
36
287
10
65
1.54
0.55
2.2
2.6
—
—
—
0
0
8
123
0.65
0.54
1.5
1.6
—
—
—
0
0
9
60
1.50
0.54
1.0
1.2
—
—
—
0
0
11
74
1.49
0.53
1.8
1.4
1.2
1.1
promille
0.09
11
60
6
39
1.54
0.53
1.8
1.5
—
—
—
0
0
34
278
1.23
0.51
5.4
3.2
7.3
7.7
mmol/l
0.50
34
273
18
136
1.33
0.49
3.4
3.8
—
—
—
0
0
25
199
1.26
0.48
1.4
1.6
—
—
—
0
0
12
85
1.42
0.47
1.6
1.2
—
70.4
—
0
7
33
274
1.21
0.45
1.5
1.6
—
—
—
0
0
20
157
1.28
0.43
1.2
1.1
0.1
2.0
u/ml
—
5
65
5
32
1.56
0.42
2.6
1.6
—
—
—
0
0
195
1830
1.08
0.41
3.0
3.1
0.7
0.8
ug/l
0.26
125
1232
5
33
1.52
0.41
1.2
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
5.3
—
—
—
0
0
32
378
0.84
0.39
1.9
1.7
5.2
2.7
mg/l
1.07
25
273
5
35
1.43
0.39
1.2
2.9
—
—
—
0
0
5
35
1.43
0.39
1.2
2.9
—
—
—
0
0
9
70
1.29
0.36
1.3
1.5
—
—
—
0
0
6
42
1.43
0.35
1.0
1.5
—
—
—
0
0
103
949
1.09
0.35
2.9
2.6
58.5
64.3
ml/min/173m2
0.90
46
402
181
1710
1.07
0.33
1.4
1.4
—
—
—
0
0
6
87
0.69
0.33
1.2
1.7
—
—
—
0
0
31
266
1.17
0.32
1.5
1.6
—
—
—
0
0
26
221
1.18
0.30
1.6
1.7
0.8
0.9
nmol/l
0.10
20
182
23
194
1.19
0.29
1.3
1.5
—
—
—
0
0
17
140
1.22
0.27
1.2
1.1
—
—
—
0
0
33
291
1.14
0.26
1.8
1.8
2.9
4.9
iu/l
1.25
11
95
18
151
1.19
0.25
1.2
1.0
0.7
2.6
u/ml
—
5
64
10
78
1.28
0.24
1.7
1.4
16.0
14.0
u/l
—
10
73
26
228
1.14
0.22
2.0
1.8
47.8
41.4
nmol/l
0.63
26
216
10
79
1.27
0.22
1.0
1.0
608.0
633.9
ng/l
—
5
48
106
1002
1.06
0.22
3.7
3.5
1.2
1.2
mmol/l
0.31
94
854
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
11
90
1.22
0.19
1.0
1.2
—
—
—
0
0
17
149
1.14
0.15
1.4
1.5
—
—
—
0
0
32
293
1.09
0.15
1.7
2.4
44.7
75.0
ug/min
0.68
18
177
20
180
1.11
0.13
1.4
1.5
—
—
—
0
0
12
104
1.16
0.12
1.2
2.1
—
—
—
0
0
13
145
0.90
0.09
1.5
1.4
1034.1
1606.6
e6/l
—
8
100
20
217
0.92
0.09
2.8
3.7
3.7
4.3
e9/l
1.07
20
217
11
124
0.89
0.09
1.1
1.7
—
—
—
0
0
6
58
1.03
0.08
1.3
1.6
—
—
—
0
0
149
1459
1.02
0.08
8.7
7.4
—
—
—
0
0
7
64
1.09
0.08
9.4
3.5
—
—
—
0
0
33
314
1.05
0.07
1.8
1.4
—
—
—
0
0
29
305
0.95
0.06
1.3
1.5
—
—
—
0
0
11
100
1.10
0.05
1.3
1.3
—
—
—
0
0
12
111
1.08
0.04
1.2
1.3
196.9
279.8
u/l
0.82
12
106
21
200
1.05
0.03
1.2
1.4
—
—
—
0
0
34
351
0.97
0.03
1.1
1.4
—
—
—
0
0
32
310
1.03
0.03
1.3
1.2
—
—
—
0
0
16
168
0.95
0.02
1.3
1.4
—
—
—
0
0
16
168
0.95
0.02
1.3
1.4
—
—
—
0
0
16
168
0.95
0.02
1.3
1.4
—
—
—
0
0
16
168
0.95
0.02
1.3
1.4
—
—
—
0
0
18
172
1.05
0.02
1.4
1.5
—
—
—
0
0
22
224
0.98
0.00
2.8
4.0
56.8
58.3
%
0.19
22
224
10
102
0.98
0.00
1.0
1.2
—
—
—
0
0
12
122
0.98
0.00
1.7
1.4
7.7
6.8
mmol/l
0.51
12
112
15
152
0.99
0.00
1.2
1.5
—
—
—
0
0
16
157
1.02
0.00
1.1
1.6
—
—
—
0
0
34
345
0.99
0.00
1.4
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
0.00
1.2
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
1.0
—
0
5
8
83
0.96
0.00
1.4
1.2
6.1
11.6
u/l
—
8
75
0
6
0.00
0.00
0.0
3.7
—
—
—
0
0
9
94
0.96
0.00
1.1
1.6
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
59
1.02
0.00
1.3
1.6
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H8_VESTIFUNCNAS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_VESTIFUNCNAS | 1.017 [0.9, 1.14] | 0.778 |
| Birth year | 0.994 [0.99, 1.0] | 0.148 |
During the follow-up period (1.1.1998 — 31.12.2019), 998 out of 4177 females with H8_VESTIFUNCNAS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H8_VESTIFUNCNAS | 1.072 [0.92, 1.25] | 0.379 |
| Birth year | 0.988 [0.98, 1.0] | 0.018 |
During the follow-up period (1.1.1998 — 31.12.2019), 515 out of 2384 males with H8_VESTIFUNCNAS died.
Mortality risk
Mortality risk for people of age
years, who have H8_VESTIFUNCNAS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.075% | 0.234% |
| 5 | 0.553% | 1.328% |
| 10 | 1.479% | 3.317% |
| 15 | 2.903% | 6.326% |
| 20 | 4.988% | 10.675% |
Relationships between endpoints
↥Index endpoint: H8_VESTIFUNCNAS – Other/unspecified disorders of vestibular function
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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