No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
3347 |
4. Check minimum number of eventsNone |
3347 |
5. Include endpointsNone |
3347 |
6. Filter based on genotype QC (FinnGen only) |
3239 |
Control definitions (FinnGen only)
- Control exclude
- H7_GLAUCOMA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- H401
- Name in latin
- Glaucoma non hypertensivum [primarium/residuale]
Similar endpoints
↥List of similar endpoints to
Normotensive glaucoma
based on the number of shared cases.
Similar with more cases:
- Primary open-angle glaucoma, strict
- Primary open-angle glaucoma
- Glaucoma
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 19419 | 12986 | 6379 |
| Only index persons | 18134 | 12188 | 5946 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.31 | 0.37 | 0.18 |
| Only index persons | 0.38 | 0.45 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 73.06 | 73.32 | 72.54 |
| Only index persons | 72.75 | 73.01 | 72.22 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 3239 | 2071 | 1168 |
| Unadjusted period prevalence (%) | 0.66 | 0.73 | 0.54 |
| Median age at first event (years) | 72.11 | 71.65 | 72.92 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3347
- Matched controls
- 33470
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CS494
NOMESCO Finland
Other visual field testing
29.1
307.7
417
163
S01EE03
ATC
bimatoprost; ophthalmic
97.7
307.7
698
90
S01ED51
ATC
timolol, combinations; ophthalmic
88.0
307.7
1957
527
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
477.5
307.7
800
22
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
32.4
307.7
344
118
XCK00
NOMESCO Finland
Perimetry
25.5
307.7
1052
590
S01EA05
ATC
brimonidine; ophthalmic
217.0
307.7
634
36
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.5
307.7
1004
1808
S01EC54
ATC
brinzolamide, combinations; ophthalmic
173.0
307.7
342
22
S01EE05
ATC
tafluprost; ophthalmic
77.7
307.7
1058
198
H40.11
ICD-10 Finland
Low pressure glaucoma
329888.4
307.7
3334
26
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
257.0
307.7
325
14
S01ED01
ATC
timolol; ophthalmic
33.0
307.7
581
212
S01EC04
ATC
brinzolamide; ophthalmic
142.4
307.7
1313
151
S01EE04
ATC
travoprost; ophthalmic
62.8
307.7
570
109
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
52.2
307.7
711
172
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
114.6
307.7
264
25
Z96.1
ICD-10 Finland
Presence of intraocular lens
4.6
307.7
1248
3819
H40.9
ICD-10 Finland
Glaucoma, unspecified
121.1
307.7
318
29
H40.0
ICD-10 Finland
Glaucoma suspect
178.5
307.7
1380
131
114
Kela drug reimbursment
Glaucoma
355.0
307.7
2850
532
XCH05
NOMESCO Finland
Eye pressure longterm registration
276.4
307.7
369
15
CS2P4
NOMESCO Finland
Optic nerve head imaging
130.5
307.7
185
15
S01ED02
ATC
betaxolol; ophthalmic
100.2
307.7
259
28
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
288.8
307.7
794
36
XCH00
NOMESCO Finland
Eye pressure measurement
10.5
307.7
565
637
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.4
307.7
1293
3514
S01EX03, ,
ATC
53.7
307.7
343
71
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.3
307.7
1023
2184
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
5987.6
307.7
1216
*
S01EE01
ATC
latanoprost; ophthalmic
96.2
307.7
1889
445
S01EC03
ATC
dorzolamide; ophthalmic
78.5
307.7
294
41
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
32.9
307.7
346
117
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
299.6
283
*
H40
ICD-10 Finland
Glaucoma
40.4
295.6
180
47
S01EC01
ATC
acetazolamide; systemic
19.2
283.8
226
126
XCK10
NOMESCO Finland
Photography of fundus of eye
4.8
282.7
757
1908
CHD00
NOMESCO Finland
Laser trabeculoplasty
589.4
277.8
272
5
CHC05
NOMESCO Finland
Iridotomy
45.4
257.1
152
35
WX140
NOMESCO Finland
Parabulbar anesthesy
6.3
244.9
452
814
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.3
234.9
524
1123
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
+∞
188.3
179
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.7
172.5
1965
11451
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
161.2
2084
12764
H25.1
ICD-10 Finland
Senile nuclear cataract
2.6
160.8
1712
9543
F93
ICPC
Glaucoma
53.8
156.1
89
17
XCW10
NOMESCO Finland
Assessment of vision
12.1
153.1
156
135
ZXA10
NOMESCO Finland
Bilateral
2.7
145.1
1036
4697
CHD35
NOMESCO Finland
Laser goniopuncture
+∞
144.8
138
*
S01EB01
ATC
pilocarpine; ophthalmic
32.8
124.3
80
25
F38
ICPC
Eye, Other laboratory test NEC
9.2
121.2
149
168
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
14.5
110.3
100
71
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.5
95.1
778
3668
F43
ICPC
Eye, Other diagnostic procedure
6.5
89.9
149
237
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
2.1
87.6
1598
10317
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.6
86.2
580
2483
ZXC20
NOMESCO Finland
Use of chemical agents
5.3
80.3
166
326
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
111.6
80.3
87
8
H26.4
ICD-10 Finland
After-cataract
2.3
73.7
639
3057
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
723.7
72.4
71
*
CFW99
NOMESCO Finland
Other operation on conjunctiva
+∞
64.8
62
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.6
63.2
412
1722
CHD99
NOMESCO Finland
Other filtering operation
609.1
60.9
60
*
H53.4
ICD-10 Finland
Visual field defects
4.7
60.7
142
310
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
59.5
57
*
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
59.5
57
*
S01EE51
ATC
latanoprost and netarsudil; ophthalmic
155.3
58.1
61
*
SPAT1009
SPAT
Measurement of intraocular pressure
6.0
54.8
98
168
S01EA03
ATC
apraclonidine; ophthalmic
8.6
51.6
66
78
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
9.7
50.4
59
62
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
474.4
47.4
47
*
H52.1
ICD-10 Finland
Myopia
4.6
47.0
112
248
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
45.9
44
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
3.9
43.7
132
350
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.9
41.9
94
198
H40.1
ICD-10 Finland
Primary open-angle glaucoma
72.7
38.0
43
6
H40.8
ICD-10 Finland
Other glaucoma
192.1
36.8
38
*
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.8
36.4
196
739
ZXE00
NOMESCO Finland
One hour or less
1.6
35.7
1308
9585
H25.0
ICD-10 Finland
Senile incipient cataract
2.2
34.2
325
1586
A98
ICPC
Health maint/preventive medicine
2.4
32.2
3146
29051
S01EA02
ATC
dipivefrine; ophthalmic
283.8
27.8
28
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.8
27.7
144
533
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
7.6
27.6
39
52
CHC03
NOMESCO Finland
Laser iridoplasty
+∞
27.1
26
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
10.8
26.9
29
27
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
26.2
394
2252
WX002
NOMESCO Finland
Sedation and analgesia
1.6
25.2
738
5049
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
2.2
24.4
221
1055
CFB00
NOMESCO Finland
Suture of conjunctiva
48.7
24.3
29
6
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.5
24.3
152
618
3651C
ICD-9 Finland
Glaucoma, Open-angle glaucoma[MATALAPAINEGLAUKOOMA]
+∞
24.0
23
*
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
24.0
23
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
5.0
23.5
50
101
H20.1
ICD-10 Finland
Chronic iridocyclitis
5.5
22.4
43
79
CS444, ,
SPAT
32.5
22.4
29
9
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.4
21.8
43
81
WX110
NOMESCO Finland
Infiltration anesthesia
1.4
21.6
2082
17878
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
2.8
21.0
105
381
Z3231
NOMESCO Finland
Registered nurse
1.5
20.7
900
6664
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.8
20.6
105
385
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.8
19.2
279
1572
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
3.6
18.4
59
164
S01EX05
ATC
netarsudil; ophthalmic
+∞
17.7
17
*
CHF12
NOMESCO Finland
Endoscopic laser coagulation of ciliary body
+∞
17.7
17
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
17.7
17
*
CFW10
NOMESCO Finland
Conjunctival manipulation with a needle (needling)
+∞
17.7
17
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
5.5
17.4
33
60
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
16.7
1393
11467
S01EX
ATC
Other antiglaucoma preparations
+∞
16.7
16
*
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
170.8
16.5
17
*
H40.12
ICD-10 Finland
Pigmentary glaucoma
170.8
16.5
17
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
1.9
16.3
207
1118
ZXA05
NOMESCO Finland
Left side
1.4
15.5
890
6871
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.4
15.5
992
7804
CD2S4
NOMESCO Finland
Photography of eye
5.5
15.2
29
53
H20.8
ICD-10 Finland
Other iridocyclitis
6.5
14.9
24
37
H01.0
ICD-10 Finland
Blepharitis
2.0
14.8
171
894
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
2.7
14.5
76
284
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
14.2
525
3732
S18
ICPC
Laceration/cut
1.3
14.1
1522
12913
Z01.9
ICD-10 Finland
Special examination, unspecified
1.8
14.1
201
1126
TCG10
NOMESCO Finland
Removal of sutures from cornea
5.2
13.4
27
52
SPAT1310
SPAT
Counselling related to known health issue
1.4
13.4
1003
8048
-1, ,
SPAT
2.2
13.0
105
480
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
12.5
12
*
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
12.5
12
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
12.1
1729
15116
H47.2
ICD-10 Finland
Optic atrophy
6.0
12.1
21
35
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.4
12.0
684
5243
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
2.4
12.0
78
325
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
46.8
11.9
14
*
SDA03
NOMESCO Finland
Periodontal treatment
1.3
11.8
991
8057
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
11.5
11
*
3708
FHL
Trabeculectomy or equivalent
120.4
11.4
12
*
H16.0
ICD-10 Finland
Corneal ulcer
2.0
11.1
125
649
R42
ICD-10 Finland
Dizziness and giddiness
1.3
11.0
811
6463
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
43.5
10.9
13
*
SPAT1312
SPAT
General health counselling
1.3
10.9
930
7563
H52.2
ICD-10 Finland
Astigmatism
3.0
10.8
47
159
F29
ICPC
Eye symptom/complaint other
1.6
10.8
278
1825
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
10.6
1173
9870
-44
ICPC
Preventive immunization/medic
1.5
10.6
297
1989
SFA20
NOMESCO Finland
Two-surface restoration
1.3
10.5
1465
12681
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
8.5
10.5
22
26
SPAT1325
SPAT
Vaccination
1.3
10.5
1180
9945
H02.4
ICD-10 Finland
Ptosis of eyelid
2.1
10.5
103
510
CG2T4
NOMESCO Finland
Topography assessment of cornea
3.5
10.4
35
101
S01BC03
ATC
diclofenac; ophthalmic
2.3
10.4
74
321
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
110.4
10.4
11
*
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
110.4
10.4
11
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.2
10.4
86
398
SPAT1153
SPAT
Removal of sutures
1.3
10.4
1061
8831
CKD40
NOMESCO Finland
Endophotocoagulation of retina
2.8
10.3
50
180
F99
ICPC
Eye/adnexa disease other
3.9
10.3
29
74
OAB50, ,
SPAT
1.7
10.2
174
1029
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.6
10.1
244
1580
SPAT1260
SPAT
Consultation of another employee
1.4
10.0
560
4272
AA1AD
NOMESCO Finland
CT of head and brain
1.3
9.9
979
8106
SPAT1301
SPAT
No procedures
1.3
9.8
1037
8659
S01BA04
ATC
prednisolone; ophthalmic
2.2
9.6
74
333
S01XA18
ATC
ciclosporin; ophthalmic
3.7
9.6
29
78
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
2.1
9.6
83
392
CKC12
NOMESCO Finland
Photocoagulation of retina
1.9
9.5
112
591
H02
ICPC
Hearing complaint
1.4
9.5
521
3955
WX723
NOMESCO Finland
CPAP therapy
2.0
9.5
93
461
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
9.4
689
5467
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
9.4
9
*
L03
ICPC
Low back symptom/complaint
1.3
9.3
796
6455
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
2.5
9.3
55
220
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
1.8
9.1
126
702
D82
ICPC
Teeth/gum disease
1.3
9.0
851
6983
SFA10
NOMESCO Finland
One-surface restoration
1.3
9.0
1417
12366
XF404
NOMESCO Finland
Ambulatory ECG
1.5
9.0
300
2082
SDA04
NOMESCO Finland
Demanding periodontal treatment
1.3
9.0
628
4946
CFD10
NOMESCO Finland
Repair of conjunctiva
18.6
8.9
13
7
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
4.2
8.9
23
55
Z01.8
ICD-10 Finland
Other specified special examinations
1.3
8.8
657
5220
H25.8
ICD-10 Finland
Other senile cataract
1.4
8.8
461
3472
WX780
NOMESCO Finland
Remote monitoring CPAP
1.9
8.7
98
510
L57.0
ICD-10 Finland
Actinic keratosis
1.4
8.6
428
3194
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
3.3
8.6
32
99
H33.0
ICD-10 Finland
Retinal detachment with retinal break
2.0
8.6
90
457
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.2
8.5
1666
14864
ZXC50
NOMESCO Finland
Cryotherapy
1.8
8.5
124
703
I49.5
ICD-10 Finland
Sick sinus syndrome
1.7
8.5
159
967
ZXA00
NOMESCO Finland
Right side
1.3
8.5
896
7453
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
8.4
1889
17100
CHD20
NOMESCO Finland
Posterior sclerotomy
+∞
8.3
8
*
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
8.3
699
5642
I48.2
ICD-10 Finland
Chronic atrial fibrillation
1.6
8.1
164
1017
ZXE10
NOMESCO Finland
More than one and less than three hours
1.2
8.1
1123
9632
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.1
8.1
32
103
WX402
NOMESCO Finland
General anaesthesia
1.3
8.1
540
4223
UDC00
NOMESCO Finland
Ear microscopy
1.5
7.9
217
1449
SPAT1281
SPAT
Other administrative function
1.5
7.7
233
1585
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.3
7.6
769
6345
SPAT1263
SPAT
Sampling
1.2
7.6
1266
11063
H35.37
ICD-10 Finland
Macular holes
2.2
7.6
61
281
Z01.2
ICD-10 Finland
Dental examination
1.2
7.4
1127
9741
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.5
7.4
213
1435
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
7.4
647
5243
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.4
1432
12695
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.5
7.3
239
1652
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.4
7.3
311
2259
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
7.2
941
7993
H53.1
ICD-10 Finland
Subjective visual disturbances
1.6
7.2
186
1223
N17
ICPC
Vertigo/dizziness
1.3
7.2
425
3257
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
6.2
7.2
18
29
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
7.2
871
7336
S01FA01
ATC
atropine; ophthalmic
4.3
7.2
18
42
J01CA04
ATC
amoxicillin; systemic
1.2
7.2
2364
22086
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
2.0
7.2
74
375
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
2.5
7.2
42
168
SPAT1249
SPAT
Treatment-related counselling outside office
1.2
7.2
1143
9924
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
3.6
7.1
23
65
H44.0
ICD-10 Finland
Purulent endophthalmitis
7.9
7.1
15
19
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
7.1
1120
9714
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
1.8
7.1
94
519
L17
ICPC
Foot/toe symptom/complaint
1.2
7.0
876
7401
WZC15, ,
NOMESCO Finland
3.5
7.0
23
66
K78
ICPC
Atrial fibrillation/flutter
1.4
7.0
301
2194
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
1.5
6.9
178
1171
R01AD09
ATC
mometasone; nasal
1.2
6.8
1130
9836
WX144
NOMESCO Finland
Subconjunctival anesthesy
2.4
6.8
45
191
D07AC01
ATC
betamethasone; topical
1.2
6.7
1033
8925
S01AD03
ATC
aciclovir; ophthalmic
1.8
6.7
102
588
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.3
6.6
576
4659
S01BC05
ATC
ketorolac; ophthalmic
1.6
6.6
136
849
H26.2
ICD-10 Finland
Complicated cataract
2.6
6.6
37
145
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.2
6.6
1413
12609
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.5
6.5
173
1146
SCA02
NOMESCO Finland
Preventive oral health care
1.5
6.5
208
1436
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
1.6
6.4
155
1006
H35.36
ICD-10 Finland
Macular cyst
2.9
6.4
29
102
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
1.4
6.3
281
2058
L82
ICD-10 Finland
Seborrhoeic keratosis
1.3
6.3
568
4611
XKD00
NOMESCO Finland
Uroflowmetry
1.3
6.3
448
3526
S29
ICPC
Skin symptom/complaint other
1.3
6.3
579
4713
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.7
6.3
117
713
S01EXXX, ,
ATC
+∞
6.3
6
*
CHD60
NOMESCO Finland
Deep sclerectomy without implant
+∞
6.3
6
*
A04
ICPC
Weakness/tiredness general
1.3
6.2
449
3541
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.2
6.2
1544
13937
SCA01
NOMESCO Finland
Preventive oral health care, short
1.3
6.2
620
5097
H13
ICPC
Plugged feeling ear
1.3
6.2
628
5171
G04BD12
ATC
mirabegron; oral
1.3
6.2
428
3355
G04CA02
ATC
tamsulosin; oral
1.3
6.2
647
5348
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
3.7
6.2
19
52
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.2
1067
9307
SPAT1043
SPAT
Audiometry
1.3
6.2
377
2905
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
3.8
6.1
18
48
H91.1
ICD-10 Finland
Presbycusis
1.4
6.1
261
1902
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
10.0
6.0
11
11
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
2685
22834
1.89
45.86
20.6
20.5
15.10
15.52
%
3.08
2609
22392
3212
29596
3.11
39.78
26.0
25.6
39.36
39.05
%
1.86
2867
27200
3212
29608
3.10
39.51
26.0
25.5
241.23
246.15
e9/l
3.99
3106
28657
3212
29612
3.10
39.42
25.9
25.5
6.66
6.82
e9/l
3.77
3086
28545
3212
29615
3.10
39.36
26.0
25.5
4.36
4.37
e12/l
0.63
3086
28547
3169
29020
2.73
39.32
20.5
20.5
139.59
139.60
mmol/l
0.13
3072
28262
3212
29622
3.09
39.20
26.1
25.7
131.78
131.72
g/l
0.07
3138
29048
3172
29073
2.74
39.06
20.8
20.7
3.98
3.99
mmol/l
0.20
3070
28275
3155
28876
2.61
38.35
20.5
20.6
80.43
79.85
umol/l
0.37
3155
28868
3146
28889
2.48
35.55
11.8
11.6
24.03
24.04
u/l
0.01
2945
27557
566
3312
1.85
35.54
3.9
3.7
—
—
—
0
0
3027
27379
2.10
35.35
5.7
5.5
2.54
2.62
mmol/l
5.14
2630
24481
1077
7606
1.61
33.84
1.7
1.6
1.27
1.33
mmol/l
1.98
791
6255
2910
26058
1.89
33.61
6.6
6.5
40.58
40.69
mmol/mol
0.27
2544
23521
2867
25586
1.84
33.02
5.4
5.1
3.02
2.09
mu/l
0.47
2486
22838
2986
27092
1.95
31.27
5.3
5.2
6.01
6.06
mmol/l
1.09
2568
24010
2943
26578
1.89
31.25
5.0
4.8
4.48
4.55
mmol/l
3.20
2559
23856
2915
26317
1.83
29.99
5.0
4.8
1.51
1.49
mmol/l
1.51
2513
23442
2997
27422
1.89
27.70
16.8
17.2
23.66
25.90
mg/l
3.36
2410
22333
1548
12295
1.48
26.55
12.4
10.3
0.00
0.00
e9/l
1.98
1285
9906
457
2764
1.76
25.07
4.0
3.7
1.23
1.23
mmol/l
0.25
376
2374
2421
21363
1.48
21.92
4.4
4.2
14.98
15.12
pmol/l
1.78
2066
18892
2787
25391
1.58
21.18
4.3
4.3
1.23
1.28
mmol/l
4.34
2364
22321
2830
25973
1.58
19.74
17.1
16.5
71.98
72.54
ml/min/173m2
0.83
2403
21453
1001
7713
1.42
18.19
4.7
4.8
0.00
0.00
estimate
0.69
431
2490
2388
21358
1.41
17.35
4.6
4.3
13.95
14.68
mm/h
1.45
2120
19445
1815
15556
1.36
16.89
21.0
18.3
1.32
1.34
inr
0.45
673
4216
1097
8794
1.37
15.15
3.3
3.3
0.41
0.53
e6/l
1.29
850
6733
868
6710
1.40
14.93
2.6
2.7
6.58
5.70
e6/l
0.84
756
6009
1664
14233
1.34
14.87
4.4
4.3
0.00
0.00
estimate
1.23
474
2828
1289
10618
1.35
14.85
4.7
4.7
—
—
—
0
0
913
7134
1.38
14.69
1.9
1.7
37825870.53
18923629.42
pmol/l
0.47
653
5702
1356
11296
1.34
14.34
3.0
2.9
131.24
146.66
ug/l
1.70
1173
10148
2511
22907
1.39
14.32
7.3
7.7
78.89
80.73
u/l
1.10
2310
21369
708
5354
1.41
13.68
1.3
1.2
1.77
1.74
u/ml
0.01
169
1284
2244
20201
1.34
13.35
5.6
5.3
143.61
2727.97
e6/l
5.03
18
313
1886
16572
1.32
13.27
6.1
6.6
1.22
1.22
mmol/l
1.02
1472
13987
140
712
2.01
13.13
3.9
4.5
2.17
2.82
mmol/l
2.27
100
495
1668
14424
1.31
13.12
4.5
4.3
0.00
0.00
estimate
1.08
449
2553
1648
14228
1.31
13.12
5.9
5.7
0.00
0.00
estimate
-0.00
451
2584
1149
9527
1.31
11.93
3.4
3.4
148.91
80.24
e6/l
0.71
890
7339
2017
18032
1.30
11.77
4.6
4.7
6.74
6.84
mmol/l
1.41
1902
16962
1717
15089
1.28
11.18
5.4
5.8
1.22
1.21
mmol/l
1.85
1530
13562
1287
10919
1.29
11.01
4.0
3.9
127.60
130.10
e6/l
0.03
935
7810
990
8156
1.30
10.48
1.5
1.6
21.37
20.79
nmol/l
0.52
789
6797
1596
13971
1.27
10.44
4.3
4.6
34.89
34.68
g/l
0.79
1450
12843
858
7023
1.30
9.34
2.0
1.8
1259.83
1180.78
nmol/l
1.53
614
5141
128
712
1.83
9.27
2.4
2.5
15.79
15.75
%
0.04
57
374
1446
12668
1.25
8.85
2.3
2.2
82.73
80.54
nmol/l
2.07
1230
10977
1116
9536
1.26
8.39
2.4
2.5
69.54
67.93
u/l
0.06
995
8667
1785
16061
1.24
8.39
3.1
3.2
51.19
54.73
u/l
0.82
1575
14431
952
8029
1.26
7.92
5.7
5.5
9.68
3.74
ug/l
0.55
810
7101
1456
12886
1.23
7.77
2.2
2.3
—
—
—
0
0
1552
13850
1.22
7.57
2.2
2.1
97.13
94.65
pmol/l
1.02
714
6783
1456
12933
1.22
7.36
6.2
5.9
0.68
0.67
%
0.51
1358
11927
584
4687
1.30
7.18
1.5
1.5
2.79
2.61
g/l
0.60
306
2568
1278
11230
1.22
7.11
2.9
3.4
2.35
2.36
mmol/l
0.74
1096
9566
1486
13290
1.21
6.84
6.2
5.9
3.01
2.81
%
2.53
1387
12269
1491
13354
1.21
6.72
6.4
6.2
9.07
8.88
%
1.52
1392
12338
1102
9583
1.22
6.70
3.3
3.2
480.76
341.96
mg/l
0.39
640
5870
1131
9862
1.22
6.69
2.1
2.1
185.43
202.53
u/l
0.26
1035
9159
1512
13573
1.21
6.62
6.3
6.1
26.56
26.43
%
0.16
1409
12571
1114
9729
1.22
6.43
3.3
3.1
6.60
6.70
mmol/l
0.33
882
7982
954
8216
1.23
6.30
2.4
2.3
2.81
3.11
mg/l
3.95
781
6920
1754
16015
1.20
6.27
5.3
6.2
11.76
11.75
umol/l
0.01
1627
15144
1485
13367
1.20
6.16
6.1
5.9
58.27
58.31
%
0.04
1380
12370
577
4710
1.27
6.14
2.4
2.5
2.32
2.29
g/l
0.55
501
4321
53
255
2.10
5.97
1.7
1.5
—
—
—
0
0
94
551
1.73
5.84
4.0
3.4
57.37
58.20
%
0.26
94
551
545
4454
1.27
5.72
2.5
2.6
21.54
21.31
%
0.14
424
3747
1381
12406
1.19
5.72
4.3
4.1
39.48
110.03
ng/l
1.13
1077
9527
411
3245
1.30
5.66
3.4
3.0
209.39
227.04
ng/l
0.54
379
2976
1146
10141
1.20
5.57
4.0
3.8
11.81
8.48
mg/mmol
1.15
659
6096
1601
14596
1.19
5.53
5.8
5.8
0.20
0.19
e9/l
0.82
1396
12504
759
6487
1.22
5.27
4.3
4.1
222.73
431.43
ng/l
0.82
659
5603
607
5069
1.24
5.26
2.5
2.5
12.19
12.03
umol/l
0.23
539
4676
968
8483
1.20
5.16
3.2
3.2
36.04
35.68
u/l
0.03
889
7977
768
6587
1.22
5.13
2.7
3.1
2.46
2.47
mmol/l
0.82
671
5739
1575
14397
1.18
5.13
5.7
5.7
1.82
1.88
e9/l
0.42
1376
12437
116
748
1.57
5.02
4.2
6.5
106.21
105.12
mmol/l
1.88
104
667
184
1319
1.42
4.75
1.2
1.2
207.61
180.20
u/ml
0.31
169
1194
262
1996
1.34
4.67
2.5
2.7
10.52
10.47
g/l
0.06
229
1816
105
686
1.55
4.34
3.0
2.8
1.71
1.73
mg/l
0.06
93
610
35
691
0.50
4.16
4.1
3.9
27.91
28.11
mg/l
0.01
22
431
469
3906
1.23
4.13
1.8
1.8
—
—
—
0
0
463
3875
1.23
3.89
1.8
1.8
—
—
—
0
0
535
4546
1.21
3.87
3.5
3.3
0.76
0.81
ug/l
0.46
387
3268
1774
16601
1.15
3.73
8.3
9.0
4.12
4.21
e9/l
0.83
1551
14327
646
5608
1.19
3.69
1.9
1.9
—
—
—
0
0
734
6444
1.18
3.67
4.7
4.7
22.19
21.98
%
0.13
384
3444
208
1591
1.33
3.66
1.8
1.8
1.30
1.43
g/l
0.41
179
1428
578
4974
1.20
3.64
1.8
2.0
30.72
29.86
s
1.89
550
4797
58
346
1.69
3.52
1.8
1.5
—
—
—
0
0
519
4446
1.20
3.44
1.3
1.3
36.53
39.27
iu/ml
0.16
168
1401
34
174
1.96
3.38
1.8
1.4
—
—
—
0
0
34
175
1.95
3.33
1.8
1.4
—
—
—
0
0
122
874
1.41
3.27
1.9
1.7
—
—
—
0
0
346
2871
1.23
3.18
1.7
1.9
120.01
152.78
ug/g
1.49
261
2201
183
1415
1.31
3.03
3.7
4.8
0.90
0.87
%
0.53
170
1327
21
93
2.27
3.03
1.2
1.1
—
—
—
0
0
332
2766
1.22
2.95
1.2
1.3
—
—
—
0
0
14
52
2.70
2.88
1.2
1.1
—
—
—
0
0
304
2520
1.23
2.84
2.1
2.2
418.87
375.97
nmol/l
0.90
274
2268
365
3083
1.21
2.83
2.7
2.5
66.66
68.57
e9/l
0.55
282
2324
449
3868
1.19
2.80
3.7
4.1
238.79
248.53
u/l
0.96
424
3617
102
730
1.41
2.79
1.6
1.5
—
—
—
0
0
465
4019
1.18
2.79
2.2
2.4
1.72
1.82
%
1.62
401
3527
182
1431
1.29
2.70
3.6
4.8
1.53
1.54
%
0.06
170
1340
353
4142
0.83
2.64
7.1
7.9
—
—
—
0
0
32
176
1.83
2.63
1.1
1.1
—
—
—
0
0
35
199
1.77
2.59
1.7
1.4
—
—
—
0
0
9
25
3.61
2.57
4.4
5.1
—
—
—
0
0
101
734
1.39
2.56
1.9
1.7
—
—
—
0
0
23
115
2.01
2.50
1.1
1.1
—
—
—
0
0
30
165
1.83
2.48
1.2
1.3
2.00
0.96
u/ml
0.39
21
94
1162
10782
1.12
2.47
3.1
3.1
1593.63
1659.42
ng/l
0.16
1004
9351
21
102
2.07
2.47
1.1
1.1
1.12
1.06
ratio
—
9
29
94
1273
0.73
2.37
3.0
4.0
24.89
24.99
mmol/l
0.13
84
1158
36
213
1.70
2.35
1.3
1.2
—
—
—
0
0
687
7590
0.88
2.32
2.3
2.4
—
—
—
0
0
62
421
1.48
2.30
1.7
1.5
—
—
—
0
0
98
724
1.36
2.28
1.6
1.4
—
—
—
0
0
95
699
1.37
2.27
1.6
1.5
—
—
—
0
0
18
86
2.10
2.22
1.1
1.1
—
10.54
u/ml
—
0
13
471
4152
1.16
2.22
5.4
5.3
1.02
1.04
mmol/l
0.61
439
3798
104
784
1.34
2.15
2.2
2.2
123.68
126.15
g/l
0.37
78
552
75
537
1.41
2.13
1.7
1.6
—
—
—
0
0
346
2989
1.18
2.12
2.1
2.6
66.45
66.07
g/l
0.44
316
2669
475
4214
1.15
2.06
1.3
1.2
20.51
14.02
u/ml
0.66
155
1429
578
5196
1.14
2.06
2.6
2.9
0.82
0.81
mmol/l
1.34
537
4797
58
399
1.46
2.05
1.6
1.4
—
—
—
0
0
13
57
2.29
1.97
1.3
1.2
—
—
—
0
0
25
141
1.78
1.96
1.4
1.4
3.00
1.67
%
—
6
27
5
11
4.55
1.94
1.0
1.0
—
—
—
0
0
312
2730
1.16
1.67
3.8
3.5
100.25
92.89
ng/l
0.55
258
2275
142
1160
1.23
1.64
2.8
2.7
—
—
—
0
0
673
6198
1.11
1.59
1.6
1.8
1.55
1.46
mg/l
0.20
509
4819
19
106
1.80
1.58
1.2
1.3
140.11
150.47
mmol/24h
0.22
19
106
6
20
3.00
1.58
1.2
1.0
—
—
—
0
0
42
288
1.46
1.57
1.6
1.6
25.50
22.81
u/ml
—
8
57
61
451
1.36
1.51
1.6
1.4
—
—
—
0
0
144
1195
1.21
1.46
2.4
3.1
37.75
105.40
mg/l
0.83
103
984
44
310
1.42
1.45
1.7
1.3
281.69
275.16
mosm/kgh2o
0.81
35
218
93
1162
0.79
1.40
2.0
2.2
378.83
525.46
ug/l
0.55
86
1097
143
1192
1.21
1.39
2.4
3.2
73.40
63.42
mg/l
0.08
101
981
14
74
1.90
1.39
1.3
1.2
—
—
—
0
0
186
1590
1.18
1.38
2.8
3.0
4.26
4.34
pmol/l
0.57
163
1362
28
182
1.54
1.37
3.9
4.0
—
—
—
0
0
85
672
1.27
1.35
1.3
1.2
—
—
—
0
0
26
168
1.55
1.31
1.9
1.7
—
—
—
0
0
66
507
1.31
1.31
1.6
1.4
—
—
—
0
0
81
1014
0.79
1.27
4.2
3.8
3.92
3.89
mmol/l
0.28
81
1005
819
7694
1.09
1.26
2.9
2.8
4035.80
6505.92
umol/l
1.06
684
6505
69
537
1.29
1.25
1.6
1.7
—
—
—
0
0
31
212
1.47
1.22
1.2
1.2
—
—
—
0
0
13
71
1.83
1.19
1.2
1.1
1604.23
1777.49
miu/ml
0.28
13
71
114
947
1.21
1.19
3.2
3.2
0.78
0.82
nmol/l
0.47
95
730
6
26
2.31
1.18
1.3
1.0
—
—
—
0
0
240
2121
1.14
1.18
5.3
6.4
24.17
24.79
mmol/l
2.14
229
2015
151
1289
1.18
1.17
1.8
2.1
12.38
11.63
nmol/l
0.50
123
1102
42
307
1.37
1.17
1.0
1.1
—
27.41
—
0
10
91
740
1.24
1.17
1.6
1.5
17.01
0.96
iu/ml
0.55
22
174
86
695
1.24
1.17
1.6
1.8
10.20
12.42
mg/l
1.71
76
638
118
986
1.20
1.16
1.4
1.2
0.18
0.86
u/ml
—
6
92
184
2111
0.86
1.15
8.9
8.0
0.69
0.68
%
0.17
184
2099
148
1264
1.18
1.15
1.2
1.5
19.94
22.38
u/ml
—
5
31
185
2120
0.87
1.14
8.9
7.9
1.25
1.33
%
0.69
185
2108
63
493
1.28
1.12
1.3
1.2
61.67
44.18
u/ml
—
6
62
11
58
1.90
1.12
1.1
1.2
1.63
1.53
mmol/l
—
5
39
136
1158
1.18
1.10
2.4
3.1
2.95
2.16
ratio
—
7
88
373
4082
0.90
1.10
5.1
4.9
34.39
33.75
%
0.52
236
2563
9
164
0.55
1.08
4.8
3.2
—
—
—
0
0
134
1143
1.18
1.07
1.1
1.1
—
—
—
0
0
13
74
1.76
1.06
1.5
1.5
9.56
9.19
ug/l
0.15
13
74
113
951
1.19
1.06
1.5
1.4
270.11
274.55
ug/g
0.08
64
568
116
979
1.19
1.05
1.5
1.6
171.43
296.89
titre
—
7
45
25
170
1.47
1.04
2.3
2.2
54.40
163.46
ug/min
—
10
37
811
7675
1.07
1.03
3.7
3.9
85.93
86.64
%
0.32
785
7480
5
22
2.27
1.03
1.6
1.2
—
—
—
0
0
50
386
1.30
1.01
1.8
1.4
67.25
61.08
%
0.46
24
241
92
764
1.21
1.00
1.3
1.3
—
—
—
0
0
22
147
1.50
1.00
1.5
1.3
—
—
—
0
0
76
619
1.23
1.00
1.6
1.7
3.44
4.51
iu/l
0.77
17
191
16
99
1.62
0.99
1.2
1.3
3.91
3.21
mmol/l
0.44
16
90
11
61
1.81
0.98
1.9
1.6
—
—
—
0
0
38
285
1.34
0.94
2.0
1.4
24.44
28.39
%
0.31
18
177
347
3184
1.10
0.93
6.5
7.2
119.05
119.03
g/l
0.01
337
3095
144
1650
0.87
0.93
2.4
2.8
0.21
0.34
e6/l
1.17
138
1619
52
409
1.28
0.93
1.6
1.4
—
—
—
0
0
6
28
2.14
0.91
1.0
1.1
—
—
—
0
0
33
244
1.36
0.90
1.3
1.4
105.00
400.38
titre
—
6
26
178
2000
0.88
0.87
1.5
1.6
1.78
1.59
%
0.38
128
1652
55
440
1.25
0.87
1.1
1.1
—
—
—
0
0
49
614
0.80
0.85
1.3
1.6
1.39
3.83
mg/l
2.09
36
480
177
1985
0.89
0.85
2.8
3.6
2.25
2.05
mmol/l
0.32
122
1474
21
145
1.45
0.84
1.5
1.3
—
—
—
0
0
33
433
0.76
0.82
1.3
1.4
—
—
—
0
0
66
544
1.22
0.81
1.4
1.4
—
—
—
0
0
121
1053
1.15
0.81
2.0
1.8
—
—
—
0
0
25
340
0.73
0.80
2.2
3.0
—
—
—
0
0
583
5508
1.07
0.79
3.0
2.9
0.92
1.29
e6/l
1.74
338
3147
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
384
3573
1.08
0.78
1.3
1.3
—
—
—
0
0
16
106
1.51
0.78
1.3
1.5
38.64
91.45
umol/l
2.25
11
62
192
1727
1.12
0.78
2.6
2.5
32.44
23.21
au/ml
—
10
92
29
216
1.35
0.78
2.0
1.4
—
—
—
0
0
61
502
1.22
0.77
5.1
4.6
354.86
3818.41
iu/ml
—
7
70
127
1444
0.87
0.77
1.8
1.9
—
—
—
0
0
6
34
1.77
0.76
1.0
1.0
—
—
—
0
0
6
34
1.77
0.76
1.0
1.0
—
—
—
0
0
1422
13808
1.05
0.76
2.5
2.7
—
—
—
0
0
0
28
0.00
0.76
0.0
2.0
—
1.37
—
0
18
98
845
1.16
0.75
1.5
1.3
—
—
—
0
0
57
468
1.22
0.75
2.1
2.1
31.33
25.28
mg/l
—
9
103
13
83
1.57
0.75
1.5
1.2
—
—
—
0
0
542
5123
1.07
0.74
3.1
3.1
1.86
2.91
e6/l
3.21
296
2787
5
25
2.00
0.72
1.2
1.1
103.40
99.16
%
—
5
25
9
56
1.61
0.72
1.0
1.3
—
—
—
0
0
16
109
1.47
0.70
1.1
1.1
—
—
—
0
0
96
1104
0.87
0.70
1.2
1.2
—
—
—
0
0
7
41
1.71
0.70
1.4
1.6
—
—
—
0
0
12
180
0.67
0.67
1.0
1.3
—
—
—
0
0
12
180
0.67
0.67
1.0
1.3
—
—
—
0
0
45
550
0.82
0.66
3.9
3.7
1.44
1.43
%
0.00
39
481
14
94
1.49
0.66
1.4
1.3
77.15
412.07
ug/l
—
9
48
66
559
1.18
0.65
1.4
1.3
22.21
30.68
e6/l
0.19
53
430
111
1254
0.88
0.64
2.4
3.2
199.71
2386.89
u/ml
1.53
98
1054
66
560
1.18
0.64
1.5
1.4
912.67
1302.08
e6/l
0.32
58
458
21
279
0.75
0.61
1.1
1.1
—
—
—
0
0
8
50
1.60
0.61
1.3
1.0
—
—
—
0
0
13
88
1.48
0.60
1.8
1.7
—
—
—
0
0
26
200
1.30
0.60
1.2
1.1
—
—
—
0
0
125
1119
1.12
0.60
1.9
1.7
39.65
38.57
u/l
0.24
110
962
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
31
245
1.27
0.59
1.3
1.1
—
4.54
—
0
5
120
1340
0.89
0.59
1.8
1.8
—
—
—
0
0
14
196
0.71
0.57
1.1
1.0
—
—
—
0
0
192
2084
0.92
0.56
2.9
3.6
5.18
5.16
kpa
0.12
178
1963
6
37
1.62
0.55
1.7
1.1
—
—
—
0
0
21
160
1.31
0.53
1.5
1.7
7.81
2.55
u/field
0.39
16
103
22
169
1.30
0.53
2.2
1.4
—
—
—
0
0
6
39
1.54
0.53
1.2
1.1
—
—
—
0
0
9
62
1.45
0.53
1.2
1.2
—
—
—
0
0
9
63
1.43
0.52
1.7
2.3
156.33
213.54
%
—
9
57
6
40
1.50
0.51
1.7
1.1
—
—
—
0
0
169
1556
1.09
0.50
1.4
1.3
43.32
55.21
au/ml
—
6
89
6
41
1.46
0.50
2.3
2.2
—
—
—
0
0
20
153
1.31
0.50
1.1
1.1
—
—
—
0
0
16
118
1.36
0.50
1.2
1.1
—
—
—
0
0
41
343
1.20
0.50
6.4
4.2
356.35
346.73
umol/l
0.19
34
298
16
119
1.35
0.48
1.5
1.4
20.44
1370.60
u/l
—
8
43
75
663
1.13
0.47
1.2
1.3
9.60
5.88
u/ml
—
7
116
88
786
1.12
0.47
2.1
2.2
242.92
74.97
ug/min
1.23
46
450
365
3467
1.06
0.47
6.3
6.8
96.38
95.41
%
4.14
351
3336
156
1438
1.09
0.46
1.2
1.2
134.89
140.05
iu/ml
0.06
54
495
352
3343
1.06
0.46
2.6
2.6
6.33
9.00
umol/l
4.62
296
2908
74
655
1.13
0.46
1.2
1.2
1.00
4.39
u/ml
—
5
68
29
352
0.82
0.45
2.0
3.3
3.00
6.18
nmol/l
2.13
29
339
21
165
1.27
0.45
1.2
1.1
1.38
18.02
nmol/l
—
5
37
33
395
0.83
0.44
1.6
1.8
25.19
24.99
ug/l
0.01
33
386
61
535
1.14
0.44
1.3
1.2
—
—
—
0
0
16
121
1.32
0.44
1.4
1.2
—
—
—
0
0
18
139
1.30
0.43
1.2
1.0
—
—
—
0
0
10
140
0.71
0.43
1.1
1.2
9.46
9.81
mmol/l
—
10
132
10
140
0.71
0.43
1.3
1.3
—
—
—
0
0
5
32
1.56
0.42
1.6
1.1
—
—
—
0
0
36
424
0.85
0.41
1.3
1.4
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
83
747
1.11
0.41
1.6
2.2
91.72
88.62
%
0.71
78
718
0
17
0.00
0.40
0.0
11.5
—
—
—
0
0
368
3850
0.95
0.40
3.6
3.9
7.10
24.09
ug/l
3.68
299
3159
18
141
1.28
0.40
2.0
2.3
42.73
40.40
%
0.16
11
85
36
422
0.85
0.40
1.3
1.4
—
—
—
0
0
36
422
0.85
0.40
1.3
1.4
—
—
—
0
0
5
35
1.43
0.39
2.0
1.6
29.20
46.29
umol/l
—
5
35
0
19
0.00
0.39
0.0
1.3
—
0.86
—
0
12
14
106
1.32
0.39
1.5
1.1
93.57
470.14
ng/l
—
7
28
27
224
1.21
0.38
1.8
1.5
—
—
—
0
0
60
533
1.13
0.38
1.1
1.1
—
—
—
0
0
15
192
0.78
0.38
2.7
2.4
—
—
—
0
0
18
225
0.80
0.38
3.6
4.7
163.98
81.31
u/ml
—
5
61
37
318
1.17
0.36
1.3
1.2
3.17
4.15
u/ml
0.19
12
95
245
2582
0.94
0.36
3.1
2.8
4.36
4.44
kpa
0.32
231
2497
68
611
1.12
0.36
1.6
1.4
—
—
—
0
0
20
245
0.82
0.36
1.1
1.1
—
—
—
0
0
37
319
1.16
0.35
1.1
1.1
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
19
153
1.24
0.35
1.2
1.1
—
—
—
0
0
6
43
1.40
0.35
1.2
1.1
31.23
38.03
mg/l
—
6
35
86
785
1.10
0.35
1.7
1.7
—
—
—
0
0
19
233
0.81
0.34
1.1
1.2
—
84.45
—
0
11
12
91
1.32
0.33
1.1
1.2
—
—
—
0
0
37
425
0.87
0.33
1.2
1.4
—
—
—
0
0
28
237
1.18
0.33
1.0
1.0
1.56
2.33
u/ml
0.60
11
63
131
1404
0.93
0.33
1.8
1.9
4.08
2.28
ug/l
0.47
121
1210
77
701
1.10
0.33
1.9
2.4
189.46
208.40
%
1.24
70
664
24
285
0.84
0.32
3.8
3.0
147.16
24.57
mg/l
0.72
17
211
38
434
0.87
0.32
1.4
1.5
—
—
—
0
0
6
47
1.28
0.32
1.3
1.1
—
—
—
0
0
404
3901
1.04
0.31
6.1
6.5
0.93
1.27
mmol/l
1.18
304
3106
7
54
1.30
0.30
1.0
1.1
—
—
—
0
0
41
362
1.13
0.30
1.3
1.1
335.00
314.08
u/ml
0.18
24
204
13
102
1.28
0.30
3.8
2.3
—
—
—
0
0
13
102
1.28
0.30
3.8
2.3
—
—
—
0
0
23
271
0.85
0.29
1.2
1.2
8.52
7.90
mmol/l
0.40
23
223
12
152
0.79
0.29
1.2
1.1
—
—
—
0
0
301
3131
0.96
0.29
3.6
3.4
1.98
2.11
mmol/l
0.28
247
2664
38
430
0.88
0.29
1.2
1.4
—
—
—
0
0
84
775
1.09
0.29
1.9
2.4
3.53
3.64
g/l
0.33
78
735
23
195
1.18
0.28
1.3
1.2
1.87
2.18
mmol/l
1.54
23
183
13
103
1.26
0.28
1.1
1.2
—
—
—
0
0
8
62
1.29
0.28
1.0
1.0
—
—
—
0
0
61
668
0.91
0.27
1.4
1.6
—
—
—
0
0
8
65
1.23
0.27
1.4
1.3
—
—
—
0
0
38
427
0.89
0.27
1.2
1.4
—
—
—
0
0
59
538
1.10
0.26
1.3
1.4
—
—
—
0
0
300
2891
1.04
0.26
6.9
6.5
10.27
10.81
mmol/l
0.73
284
2736
8
66
1.21
0.26
1.0
1.1
—
—
—
0
0
258
2479
1.04
0.26
1.6
1.6
—
—
—
0
0
8
67
1.19
0.26
2.4
2.1
—
—
—
0
0
21
178
1.18
0.26
1.1
1.4
—
—
—
0
0
21
178
1.18
0.26
1.1
1.4
—
—
—
0
0
5
73
0.68
0.26
1.6
1.1
—
—
—
0
0
102
1089
0.93
0.26
1.2
1.2
—
—
—
0
0
9
74
1.22
0.25
1.3
1.1
—
—
—
0
0
107
1138
0.94
0.25
2.3
2.3
37.23
37.28
g/l
0.03
90
975
12
96
1.25
0.24
1.6
1.4
1.52
1.59
g/l
0.53
12
96
11
137
0.80
0.24
1.5
1.3
—
—
—
0
0
303
3134
0.96
0.24
3.5
3.4
5.82
5.84
kpa
0.09
289
3048
6
82
0.73
0.24
1.5
1.1
—
—
—
0
0
66
714
0.92
0.24
1.2
1.4
—
—
—
0
0
6
83
0.72
0.24
1.5
1.2
—
—
—
0
0
15
124
1.21
0.24
1.1
5.6
23186.37
60.44
mg/l
—
8
87
23
199
1.16
0.23
1.2
1.2
104.35
83.44
u/l
0.35
17
178
5
38
1.32
0.23
4.0
16.1
8.50
5.14
mmol/l
—
5
38
41
371
1.11
0.22
3.8
3.6
—
—
—
0
0
5
40
1.25
0.22
1.6
1.1
—
—
—
0
0
26
295
0.88
0.22
1.8
1.6
—
—
—
0
0
19
163
1.17
0.21
1.4
1.6
—
—
—
0
0
19
163
1.17
0.21
1.4
1.6
—
—
—
0
0
5
42
1.19
0.21
2.4
2.2
—
—
—
0
0
0
11
0.00
0.21
0.0
5.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
2.2
—
17.86
—
0
11
0
10
0.00
0.21
0.0
2.2
—
—
—
0
0
50
544
0.92
0.21
1.5
1.2
24.62
45.24
u/l
1.56
43
474
0
12
0.00
0.21
0.0
1.2
—
2.33
—
0
12
40
363
1.10
0.21
1.8
1.3
118.00
125.56
u/ml
—
7
72
31
277
1.12
0.21
2.0
2.1
2.50
1.95
u/field
0.17
12
87
244
2358
1.04
0.21
2.7
2.8
57.83
59.00
ml/min/173m2
0.19
102
1044
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
28
314
0.89
0.20
1.8
1.5
—
—
—
0
0
316
3070
1.03
0.20
2.3
2.5
5.86
6.69
ug/l
0.81
263
2605
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
129
1230
1.05
0.20
2.5
2.5
1.62
1.03
g/l
0.71
101
1050
34
307
1.11
0.20
1.3
1.2
2.21
5.33
u/ml
1.96
14
143
200
1929
1.04
0.19
1.4
1.5
—
—
—
0
0
162
1686
0.96
0.19
3.0
3.1
25.31
25.28
mmol/l
0.03
151
1651
7
60
1.17
0.17
1.4
1.5
79.00
120.76
ng/l
—
7
60
159
1650
0.96
0.17
3.4
4.3
134.94
86.35
u/ml
0.23
151
1579
17
148
1.15
0.16
2.1
1.8
762.65
648.04
e6/l
0.43
17
141
19
167
1.14
0.16
1.8
1.6
86.16
87.56
umol/l
0.09
19
167
42
388
1.08
0.16
1.3
1.1
—
—
—
0
0
43
398
1.08
0.16
8.6
6.1
6.79
7.32
mmol/l
1.03
37
331
32
292
1.10
0.16
1.1
1.1
—
—
—
0
0
31
283
1.10
0.15
1.1
1.1
128.48
115.02
%
1.25
25
242
22
245
0.90
0.15
1.3
1.3
—
—
—
0
0
399
3912
1.02
0.15
6.1
6.5
12.44
12.02
kpa
0.91
382
3716
9
80
1.13
0.15
1.6
1.5
117.11
165.56
nmol/24h
—
9
80
9
81
1.11
0.15
1.1
1.3
128.72
151.93
pmol/l
—
9
81
399
3913
1.02
0.15
6.1
6.5
4.89
5.11
kpa
6.17
381
3719
25
275
0.91
0.14
1.6
1.3
—
—
—
0
0
131
1357
0.96
0.14
2.1
2.4
10.11
10.27
g/l
0.18
113
1182
8
97
0.82
0.13
1.1
1.0
—
—
—
0
0
60
568
1.06
0.13
1.1
1.2
—
0.60
—
0
6
9
107
0.84
0.13
1.0
1.2
—
—
—
0
0
22
241
0.91
0.12
1.3
1.3
—
—
—
0
0
21
191
1.10
0.11
1.1
1.3
28.44
21.93
u/l
0.38
16
165
36
337
1.07
0.11
1.3
1.3
49.04
38.69
iu/l
0.71
27
287
619
6261
0.99
0.11
4.9
4.9
1.02
1.02
kg/l
0.20
134
1009
13
146
0.89
0.10
1.2
1.0
—
—
—
0
0
30
321
0.93
0.10
1.5
1.4
—
—
—
0
0
30
321
0.93
0.10
1.5
1.4
—
—
—
0
0
14
125
1.12
0.10
1.3
1.4
8.97
14.76
umol/l
—
8
81
33
310
1.07
0.09
1.5
1.3
10507.19
137745.99
e6/l
2.31
21
202
15
135
1.11
0.09
1.5
1.4
0.89
0.98
g/l
0.48
15
135
23
213
1.08
0.09
1.0
1.1
0.23
1.45
u/ml
1.64
12
106
16
145
1.10
0.09
1.0
1.0
0.26
1.03
u/ml
1.13
11
75
20
217
0.92
0.09
2.5
2.2
—
—
—
0
0
20
184
1.09
0.09
1.3
1.7
—
—
—
0
0
83
803
1.03
0.09
1.7
1.6
11702.90
15294.26
e6/l
0.35
62
571
11
97
1.13
0.09
1.0
1.2
—
—
—
0
0
14
126
1.11
0.09
1.0
1.1
129.77
136.97
nmol/l
0.19
14
126
17
156
1.09
0.08
1.2
1.3
1.01
0.98
promille
0.04
12
123
14
127
1.10
0.08
1.4
1.6
—
—
—
0
0
14
127
1.10
0.08
1.4
1.6
—
—
—
0
0
288
2841
1.02
0.07
2.1
2.4
32.33
37.98
u/l
1.51
252
2402
6
72
0.83
0.07
1.2
1.3
116.67
114.12
%
—
6
60
6
75
0.80
0.07
1.2
1.1
—
—
—
0
0
8
75
1.07
0.07
1.0
1.3
92.30
129.04
nmol/l
—
8
54
7
80
0.87
0.07
1.4
1.1
—
—
—
0
0
19
204
0.93
0.07
1.7
1.7
—
—
—
0
0
13
118
1.10
0.07
1.2
1.1
—
—
—
0
0
59
571
1.03
0.06
1.4
1.8
4.16
4.75
mmol/24h
1.02
53
470
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
127
1245
1.02
0.06
2.8
2.8
0.36
0.35
u/ml
0.10
69
725
43
447
0.96
0.06
1.4
1.5
1058.19
2015.62
e6/l
1.40
32
315
74
760
0.97
0.06
1.3
1.3
—
—
—
0
0
74
760
0.97
0.06
1.3
1.3
—
—
—
0
0
14
129
1.09
0.05
1.4
1.6
—
—
—
0
0
90
881
1.02
0.05
2.0
1.6
—
—
—
0
0
142
1442
0.98
0.05
2.0
2.4
7.33
7.52
g/l
0.92
125
1280
97
988
0.98
0.04
2.4
2.4
0.00
0.00
g/l
-0.00
87
909
31
322
0.96
0.04
1.3
1.5
—
—
—
0
0
142
1439
0.99
0.04
2.0
2.4
—
—
—
0
0
24
229
1.05
0.04
1.0
1.0
602.84
311.17
ng/l
0.59
19
149
24
229
1.05
0.04
1.0
1.0
46.89
44.53
ng/l
0.12
19
148
170
1680
1.01
0.04
1.5
1.7
1.49
1.54
g/l
0.25
142
1452
295
2926
1.01
0.04
6.2
6.1
1.22
1.36
mmol/l
2.93
289
2853
136
1342
1.01
0.04
2.1
2.5
2.75
3.00
g/l
2.73
119
1181
63
616
1.02
0.04
3.2
2.5
34.36
32.33
umol/l
0.23
55
544
28
291
0.96
0.04
2.3
2.0
—
—
—
0
0
142
1437
0.99
0.03
2.0
2.4
3.92
3.65
g/l
0.58
125
1276
24
230
1.04
0.03
1.0
1.0
714.94
693.10
ng/l
0.06
17
145
87
857
1.02
0.03
1.2
1.2
—
—
—
0
0
32
310
1.03
0.03
1.2
1.3
13.93
14.21
u/l
0.03
24
248
226
2243
1.01
0.03
1.7
1.7
—
—
—
0
0
99
1003
0.99
0.03
2.3
2.4
0.00
0.00
g/l
-0.00
88
911
12
128
0.94
0.02
1.3
1.3
6.08
6.19
mmol/l
0.11
12
120
26
269
0.97
0.02
1.3
1.5
—
—
—
0
0
26
269
0.97
0.02
1.3
1.5
—
—
—
0
0
26
269
0.97
0.02
1.3
1.5
—
—
—
0
0
41
401
1.02
0.02
1.4
1.4
48306.25
54883.68
e6/l
0.10
24
232
10
93
1.08
0.02
1.4
1.3
36.20
33.94
%
—
5
64
49
482
1.02
0.01
1.5
1.5
—
—
—
0
0
49
482
1.02
0.01
1.5
1.5
—
—
—
0
0
17
177
0.96
0.01
1.1
1.1
—
—
—
0
0
49
498
0.98
0.01
1.6
1.4
0.69
0.81
nmol/l
0.79
40
409
19
183
1.04
0.01
1.2
1.1
—
—
—
0
0
19
183
1.04
0.01
1.2
1.1
—
—
—
0
0
19
183
1.04
0.01
1.2
1.1
—
—
—
0
0
207
2060
1.01
0.01
2.8
2.9
125.30
127.17
g/l
0.56
198
2011
54
533
1.01
0.01
1.2
1.3
—
—
—
0
0
13
124
1.05
0.00
1.2
1.4
30.05
19.78
umol/l
0.48
13
116
13
125
1.04
0.00
1.4
1.0
1.07
1.20
u/l
—
6
66
15
155
0.97
0.00
1.4
1.3
—
—
—
0
0
41
408
1.00
0.00
1.2
1.1
—
—
—
0
0
87
871
1.00
0.00
1.2
1.2
—
—
—
0
0
107
1069
1.00
0.00
2.3
2.4
0.12
0.04
g/l
0.40
93
973
301
3009
1.00
0.00
1.8
2.1
0.20
0.20
g/l
0.00
269
2792
18
181
0.99
0.00
1.2
1.1
—
—
—
0
0
18
181
0.99
0.00
1.2
1.1
—
—
—
0
0
21
209
1.00
0.00
1.4
1.6
5.08
6.83
u/l
0.27
12
170
27
271
1.00
0.00
2.4
2.2
1029.50
631.38
ml
0.98
16
172
34
341
1.00
0.00
1.1
1.2
64.81
61.14
u/l
0.16
26
307
30
304
0.99
0.00
1.2
1.2
—
—
—
0
0
31
307
1.01
0.00
1.4
1.2
160.90
191.96
miu/ml
—
10
98
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
9
99
0.91
-0.00
1.3
1.8
14.79
365.33
ug/l
—
9
92
6
61
0.98
-0.00
1.2
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
1.10
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.3
—
70.50
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
7
78
0.90
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
77
0.91
-0.00
1.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_GLAUCOMA_NTG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCOMA_NTG | 0.892 [0.81, 0.98] | 0.022 |
| Birth year | 0.993 [0.99, 1.0] | 0.113 |
During the follow-up period (1.1.1998 — 31.12.2019), 2411 out of 10420 females with H7_GLAUCOMA_NTG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCOMA_NTG | 0.969 [0.85, 1.1] | 0.63 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 1393 out of 5088 males with H7_GLAUCOMA_NTG died.
Mortality risk
Mortality risk for people of age
years, who have H7_GLAUCOMA_NTG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.051% | 0.175% |
| 5 | 0.396% | 1.106% |
| 10 | 1.104% | 2.751% |
| 15 | 2.302% | 5.426% |
| 20 | 4.091% | 8.938% |
Relationships between endpoints
↥Index endpoint: H7_GLAUCOMA_NTG – Normotensive glaucoma
GWS hits: 16
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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