Primary open-angle glaucoma, strict

H7_GLAUCOMA_POAG

open-angle glaucoma: Chronic outflow obstruction of the eye's drainage canals that can lead to increased internal eye pressure and optic nerve damage.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H40.1
  • Hospital discharge: ICD-9 3651[A|C|E|X]
  • Hospital discharge: ICD-8 37510
  • Hospital discharge: excluded ICD-10 H40.10, H40.12
  • Cause of death: ICD-10 H40.1
  • Cause of death: ICD-9 3651[A|C|E|X]
  • Cause of death: ICD-8 37510
  • Cause of death: excluded ICD-10 H40.10, H40.12

2 out of 7 registries used, show all original rules.

11140

4. Check minimum number of events

None

11140

5. Include endpoints

None

11140

6. Filter based on genotype QC (FinnGen only)

11140

Control definitions (FinnGen only)

Control exclude
H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
H40
Name in latin
Glaucoma simplex primarium

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 97098 58563 37736
Only index persons 79574 48741 30833
Unadjusted period prevalence (%)
Whole population 1.43 1.68 1.05
Only index persons 1.55 1.79 1.18
Median age at first event (years)
Whole population 71.03 71.96 69.63
Only index persons 70.76 71.66 69.33

-FinnGen-

Key figures

All Female Male
Number of individuals 11140 6159 4981
Unadjusted period prevalence (%) 2.14 2.10 2.20
Median age at first event (years) 69.77 69.47 70.14

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
9910
Matched controls
98854
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.7
323.0
1399
2755
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
99.3
323.0
537
57
XCK00
NOMESCO Finland
Perimetry
30.4
323.0
3597
1819
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.4
323.0
2905
6013
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
323.0
638
*
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.0
323.0
3459
9593
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
37.2
323.0
944
279
H40.11
ICD-10 Finland
Low pressure glaucoma
798.8
323.0
2701
46
CS494
NOMESCO Finland
Other visual field testing
34.9
323.0
1034
329
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
7.4
323.0
2455
4225
XCK10
NOMESCO Finland
Photography of fundus of eye
4.6
323.0
2206
5778
S01EE01
ATC
latanoprost; ophthalmic
102.3
323.0
5500
1189
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
323.0
495
*
XCH00
NOMESCO Finland
Eye pressure measurement
12.4
323.0
1465
1365
CHC05
NOMESCO Finland
Iridotomy
51.8
323.0
564
115
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
1847.2
323.0
505
*
H40.9
ICD-10 Finland
Glaucoma, unspecified
182.3
323.0
1177
73
S01EC03
ATC
dorzolamide; ophthalmic
99.5
323.0
1209
138
H40
ICD-10 Finland
Glaucoma
50.2
323.0
642
136
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
256.8
323.0
2205
110
114
Kela drug reimbursment
Glaucoma
478.7
323.0
8875
1740
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
3329.1
323.0
333
*
S01EX03
ATC
NA
91.7
323.0
1931
260
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.9
323.0
3153
8594
S01ED51
ATC
timolol, combinations; ophthalmic
116.5
323.0
6327
1471
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
3230.6
323.0
7379
85
S01EE04
ATC
travoprost; ophthalmic
60.9
323.0
1649
323
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.8
323.0
5666
32176
S01EE03
ATC
bimatoprost; ophthalmic
111.1
323.0
1936
216
S01EC54
ATC
brinzolamide, combinations; ophthalmic
138.0
323.0
917
73
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3665.4
323.0
3025
11
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
129.5
323.0
734
61
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.9
323.0
5503
30051
S01ED01
ATC
timolol; ophthalmic
49.8
323.0
2732
750
S01ED02
ATC
betaxolol; ophthalmic
83.0
323.0
823
108
H40.0
ICD-10 Finland
Glaucoma suspect
242.6
323.0
3649
237
CHD35
NOMESCO Finland
Laser goniopuncture
3414.2
323.0
341
*
S01EC01
ATC
acetazolamide; systemic
36.3
323.0
1201
374
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
52.2
323.0
936
197
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
725.7
323.0
1595
26
H25.1
ICD-10 Finland
Senile nuclear cataract
2.6
323.0
4572
24677
S01EE05
ATC
tafluprost; ophthalmic
67.4
323.0
2598
519
S01EC04
ATC
brinzolamide; ophthalmic
131.9
323.0
3419
393
S01EB01
ATC
pilocarpine; ophthalmic
71.9
323.0
501
73
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.6
323.0
5064
28683
CHD00
NOMESCO Finland
Laser trabeculoplasty
1247.3
323.0
1112
10
WX140
NOMESCO Finland
Parabulbar anesthesy
5.8
323.0
1055
1985
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
42.8
323.0
1612
446
XCH05
NOMESCO Finland
Eye pressure longterm registration
298.8
323.0
642
23
S01EA02
ATC
dipivefrine; ophthalmic
1062.5
317.8
310
*
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
2863.6
299.9
289
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
2811.0
294.6
284
*
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
2726.9
286.2
276
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
278.1
266
*
H40.1
ICD-10 Finland
Primary open-angle glaucoma
181.5
270.5
283
16
CHD99
NOMESCO Finland
Other filtering operation
2475.5
261.1
252
*
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.9
228.1
1585
6066
ZXA10
NOMESCO Finland
Bilateral
2.3
226.7
2593
13120
H26.4
ICD-10 Finland
After-cataract
2.6
204.9
1695
7175
F93
ICPC
Glaucoma
64.8
201.2
235
37
CS2P4
NOMESCO Finland
Optic nerve head imaging
94.0
198.8
221
24
S01EA03
ATC
apraclonidine; ophthalmic
15.8
194.6
326
212
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
187.9
180
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
170.1
163
*
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.7
155.4
378
508
CFW99
NOMESCO Finland
Other operation on conjunctiva
196.2
149.0
155
8
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.2
144.8
1700
8458
F43
ICPC
Eye, Other diagnostic procedure
7.1
144.2
370
538
H34.8
ICD-10 Finland
Other retinal vascular occlusions
5.1
141.3
474
967
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
135.6
130
*
H40.8
ICD-10 Finland
Other glaucoma
229.1
132.1
136
6
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
122.0
117
*
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
12.6
118.6
218
176
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.0
117.6
503
1304
H40.12
ICD-10 Finland
Pigmentary glaucoma
1128.6
114.7
112
*
SPAT1009
SPAT
Measurement of intraocular pressure
6.7
112.8
299
455
ZXC20
NOMESCO Finland
Use of chemical agents
4.5
109.4
407
924
3708
FHL
Trabeculectomy or equivalent
+∞
108.4
104
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.5
106.5
937
3997
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
106.3
102
*
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.6
91.1
730
2951
H20.1
ICD-10 Finland
Chronic iridocyclitis
9.7
90.8
190
199
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
+∞
90.7
87
*
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
88.6
85
*
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
76.8
87.2
99
13
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.9
84.4
366
959
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
77.3
971
4870
XCW10
NOMESCO Finland
Assessment of vision
10.9
72.4
142
132
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
8.9
69.2
151
171
CHC03
NOMESCO Finland
Laser iridoplasty
343.7
68.6
69
*
ZXA05
NOMESCO Finland
Left side
1.5
68.1
2729
19590
CHD10
NOMESCO Finland
Trabeculectomy
671.1
68.0
67
*
H52.1
ICD-10 Finland
Myopia
4.4
64.2
242
557
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
4.7
63.3
225
488
S01BC03
ATC
diclofenac; ophthalmic
3.3
63.2
339
1055
H25.8
ICD-10 Finland
Other senile cataract
1.7
62.5
1484
9270
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
57.3
55
*
CFB00
NOMESCO Finland
Suture of conjunctiva
34.9
56.2
73
21
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.6
55.4
438
1749
A98
ICPC
Health maint/preventive medicine
1.6
53.7
8564
79261
H33.0
ICD-10 Finland
Retinal detachment with retinal break
3.0
53.5
333
1149
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.6
53.5
418
1656
S01EX
ATC
Other antiglaucoma preparations
+∞
52.1
50
*
CKD40
NOMESCO Finland
Endophotocoagulation of retina
4.3
51.5
197
461
CA1ME
NOMESCO Finland
Ultrasound oculometry
6.0
51.1
146
247
CKC12
NOMESCO Finland
Photocoagulation of retina
2.4
48.9
420
1754
H16.0
ICD-10 Finland
Corneal ulcer
2.5
48.9
391
1571
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.9
48.6
315
1117
F38
ICPC
Eye, Other laboratory test NEC
9.7
48.3
100
104
S01BC05
ATC
ketorolac; ophthalmic
2.1
48.2
552
2646
S01EX05
ATC
netarsudil; ophthalmic
+∞
46.9
45
*
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.9
46.2
727
3954
H44.5
ICD-10 Finland
Degenerated conditions of globe
74.6
45.9
52
7
H26.2
ICD-10 Finland
Complicated cataract
4.3
45.2
175
415
ZXA00
NOMESCO Finland
Right side
1.4
44.1
2719
20924
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
3.2
43.7
237
745
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
43.5
3443
27657
S01FA01
ATC
atropine; ophthalmic
6.8
43.4
112
166
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.4
43.2
377
1587
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
41.7
3872
31846
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
14.7
40.9
69
47
SPAT1312
SPAT
General health counselling
1.4
40.5
2685
20864
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
140.2
39.7
42
*
37512
ICD-8 Finland
Glaucoma, Chronicum capsulare
+∞
37.5
36
*
WX110
NOMESCO Finland
Local anesthesy
1.3
35.4
5315
46466
SPAT1310
SPAT
Counselling related to known health issue
1.4
35.1
2753
21890
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
3.0
34.7
205
684
SPAT1325
SPAT
Vaccination
1.3
33.9
3434
28343
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
33.9
2026
15377
H53.4
ICD-10 Finland
Visual field defects
2.7
33.8
237
884
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
33.2
1306
9133
WX142
NOMESCO Finland
Sub-tenon anesthesy
7.1
33.1
82
116
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
3.4
30.6
154
460
WX002
NOMESCO Finland
Sedation and analgesia
1.4
30.6
1803
13615
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.5
30.5
239
952
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.8
30.2
532
3000
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
302.5
29.8
30
*
SPAT1262
SPAT
Handing over of treatment supplies
1.4
29.4
1686
12660
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
29.1
28
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
2.4
28.9
251
1057
SPAT1301
SPAT
No procedures
1.3
28.7
2907
23844
SPAT1263
SPAT
Sampling
1.3
28.4
3655
30948
SPAT1153
SPAT
Removal of sutures
1.3
28.0
2899
23831
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.4
27.9
137
402
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
16.9
27.8
44
26
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
42.5
27.6
34
8
H26.02
ICD-10 Finland
Presenil cataract
2.4
27.4
231
958
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
12.7
26.9
48
38
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
6.2
25.8
70
113
CKC20
NOMESCO Finland
Cryopexy of undetached retina
8.6
24.8
54
63
H3603, E103
ICD-10 Finland
NA
4.9
24.8
82
168
F99
ICPC
Eye/adnexa disease other
4.5
24.7
88
195
H01.0
ICD-10 Finland
Blepharitis
1.9
24.4
376
2024
S18
ICPC
Laceration/cut
1.3
24.3
3693
31734
CD2S4
NOMESCO Finland
Photography of eye
5.6
24.2
71
127
H35.36
ICD-10 Finland
Macular cyst
4.4
24.0
87
197
3626
FHL
Extracapsular cataract surgery and implantation of an artificial lens
2.4
23.7
211
902
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
23.6
2600
21448
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
3.1
23.6
130
418
H20.8
ICD-10 Finland
Other iridocyclitis
7.4
23.2
55
74
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
2.6
23.1
170
654
TCG10
NOMESCO Finland
Removal of sutures from cornea
4.8
23.1
77
160
H57.1
ICD-10 Finland
Ocular pain
2.3
23.0
222
985
3661A
ICD-9 Finland
Cataract, Senile cataract
2.5
22.7
182
735
CHC00
NOMESCO Finland
Iridotomy
120.0
22.5
24
*
S01FA04
ATC
cyclopentolate; ophthalmic
3.3
22.5
117
361
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.9
22.2
140
492
H18.1
ICD-10 Finland
Bullous keratopathy
7.5
22.2
52
69
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
4.3
22.1
82
190
H02.4
ICD-10 Finland
Ptosis of eyelid
2.1
22.1
263
1285
CKC15
NOMESCO Finland
Panretinal photocoagulation
3.6
21.9
101
284
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
21.9
21
*
3651C
ICD-9 Finland
Glaucoma, Open-angle glaucoma[MATALAPAINEGLAUKOOMA]
+∞
21.9
21
*
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
21.8
2635
21953
H13
ICPC
Plugged feeling ear
1.3
21.3
1648
12914
CFD10
NOMESCO Finland
Repair of conjunctiva
16.2
21.3
34
21
CKC10
NOMESCO Finland
Local photocoagulation of retina
2.3
21.2
194
843
CKD15
NOMESCO Finland
Injection of vitreous substitute
5.3
21.1
65
124
XCD20
NOMESCO Finland
Photoangiography of eye
2.3
21.0
198
871
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
20.5
2667
22373
N02BE01
ATC
paracetamol; systemic, rectal
1.3
20.4
7868
74311
T89
ICPC
Diabetes insulin dependent
2.1
20.3
227
1081
J01DB01
ATC
cefalexin; oral
1.2
20.3
6936
64557
H31.4
ICD-10 Finland
Choroidal detachment
22.3
20.3
29
13
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
4.3
20.3
75
174
H52.2
ICD-10 Finland
Astigmatism
3.2
20.2
107
336
CG2T4
NOMESCO Finland
Topography assessment of cornea
3.9
20.0
83
214
3702
FHL
Trabeculotomy
+∞
19.8
19
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
19.8
19
*
CHB30
NOMESCO Finland
Goniotomy
+∞
19.8
19
*
R42
ICD-10 Finland
Dizziness and giddiness
1.3
19.8
2053
16738
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.7
19.5
382
2226
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.3
19.5
2081
17024
SPAT1260
SPAT
Consultation of another employee
1.3
19.3
1507
11811
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
19.1
4966
44785
H54.4
ICD-10 Finland
Blindness, monocular
7.4
19.0
45
61
3719
FHL
Other measure in this category
+∞
18.7
18
*
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
+∞
18.7
18
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
3.7
18.6
81
219
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
18.5
3758
33016
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
2.6
18.5
140
552
S01EB02
ATC
carbachol; ophthalmic
189.8
18.5
19
*
F29
ICPC
Eye symptom/complaint other
1.5
18.5
594
3955
S01AD03
ATC
aciclovir; ophthalmic
1.8
18.5
305
1687
H27.0
ICD-10 Finland
Aphakia
6.2
18.4
49
79
-44
ICPC
Preventive immunization/medic
1.4
17.9
774
5484
H3603, E113
ICD-10 Finland
NA
3.1
17.9
100
327
CKD20
NOMESCO Finland
Removal of vitreous body substitute
4.6
17.8
61
132
H21.0
ICD-10 Finland
Hyphaema
6.1
17.7
48
79
3703
FHL
Laser operation on ventricular angle under general anesthesia
+∞
17.7
17
*
H40.21
ICD-10 Finland
Intermittent glaucoma with closed ventricular angle
+∞
17.7
17
*
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
17.7
17
*
CHD30
NOMESCO Finland
Laser trabeculectomy
179.8
17.5
18
*
A10AA01
ATC
NA
2.3
17.3
165
732
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
17.2
1112
8459
Z01.9
ICD-10 Finland
Special examination, unspecified
1.6
17.2
444
2803
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
17.2
4317
38642
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
16.4
3612
31875
CKD60
NOMESCO Finland
Anterior vitrectomy
2.8
16.3
106
383
E0000UV
ATC
NA
1.2
16.3
3033
26320
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
2.1
16.3
188
911
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.5
16.3
578
3933
H27.1
ICD-10 Finland
Dislocation of lens
4.3
16.2
59
136
CBJ40
NOMESCO Finland
Resection of levator muscle of eyelid
3.3
15.9
80
244
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
1.9
15.9
234
1244
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
15.8
1703
13905
A10AA02
ATC
NA
1.8
15.7
266
1483
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
15.6
15
*
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
4.4
15.6
56
128
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
3.9
15.6
63
161
T90
ICPC
Diabetes non-insulin dependent
1.2
15.3
2010
16792
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.1
15.3
178
867
D82
ICPC
Teeth/gum disease
1.2
14.7
2050
17225
3659X
ICD-9 Finland
Glaucoma, Unspecified glaucoma
+∞
14.6
14
*
37598
ICD-8 Finland
Glaucoma, Aliud definitum
+∞
14.6
14
*
CFW10
NOMESCO Finland
Conjunctival manipulation with a needle (needling)
+∞
14.6
14
*
3711
FHL
Cyclodiateria or cryocoagulation
149.8
14.4
15
*
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
2.3
14.4
134
589
K02.1
ICD-10 Finland
Caries of dentine
1.2
14.4
3664
32650
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.4
14.3
116
477
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
5.1
14.3
44
86
H04AA01
ATC
glucagon; nasal, parenteral
2.6
14.1
102
396
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
4.1
14.0
54
133
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.4
14.0
798
5943
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.0
13.9
183
935
H16.9
ICD-10 Finland
Keratitis, unspecified
2.5
13.8
110
449
C08CA01
ATC
amlodipine; oral
1.2
13.8
3520
31331
S01KA02
ATC
hypromellose; ophthalmic
2.0
13.8
176
892
I10
ICD-10 Finland
Essential (primary) hypertension
1.2
13.7
5941
55299
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
1.8
13.6
219
1206
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
4.4
13.6
48
109
Q15.0
ICD-10 Finland
Congenital glaucoma
75.0
13.6
15
*
H44.2
ICD-10 Finland
Degenerative myopia
7.1
13.4
32
45
CHD20
NOMESCO Finland
Posterior sclerotomy
139.8
13.4
14
*
165
Kela drug reimbursment
Preservative-free combination of bimatoprost and timolol
139.8
13.4
14
*
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.3
13.4
1248
9987
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
13.4
1868
15677
H36.01
ICD-10 Finland
Diabetic maculopathy
2.5
13.4
103
413
SPAT1043
SPAT
Audiometry
1.3
13.2
970
7512
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.2
12.9
1854
15597
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.1
12.8
70
229
SPAT1014
SPAT
Treatment of eyes
1.9
12.7
174
905
H54.1
ICD-10 Finland
Severe visual impairment, binocular
6.4
12.5
32
50
CHD60
NOMESCO Finland
Deep sclerectomy without implant
+∞
12.5
12
*
3651D
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA PIGMENTOSUM]
+∞
12.5
12
*
CBG00
NOMESCO Finland
Epilation of cilia by electrolysis
4.1
12.5
47
114
H02
ICPC
Hearing complaint
1.3
12.5
1130
9004
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.4
12.4
616
4478
37872
ICD-8 Finland
Other diseases of eye, Aphakia artefacta, acquisita
6.6
12.4
31
47
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
13.1
12.4
21
16
SPAT1130
SPAT
Esophagoscopy, gastroscopy and duodenoscopy
1.7
12.3
239
1394
H3600, E103
ICD-10 Finland
NA
3.4
12.3
58
170
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
4.3
12.1
44
103
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.3
12.1
870
6712
H3601, E103
ICD-10 Finland
NA
3.5
11.9
55
159
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
46.6
11.9
14
*
S01AX11
ATC
[U] ofloxacin; ophthalmic
1.6
11.8
318
2034
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.2
11.8
1764
14893
Z01.8
ICD-10 Finland
Other specified special examinations
1.2
11.8
1601
13381
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
11.7
2366
20559
SPAT1304
SPAT
Counselling and guidance related to ageing
1.3
11.7
737
5575
H35.37
ICD-10 Finland
Macular holes
2.1
11.7
124
584
H44.4
ICD-10 Finland
Hypotony of eye
30.0
11.6
15
5
AA1AD
NOMESCO Finland
CT of head and brain
1.2
11.6
2177
18788
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
3.3
11.6
57
174
J01CA04
ATC
amoxicillin; systemic
1.2
11.5
6447
60775
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
11.0
11.5
21
19
3651E
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA INFANTILE SEU JUVENILE]
+∞
11.4
11
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
11.4
11
*
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
2.0
11.4
136
673
CDC00
NOMESCO Finland
Enucleation of eye
25.0
11.1
15
6
Z90.0
ICD-10 Finland
Acquired absence of part of head and neck
6.7
11.1
27
40
A10AE04
ATC
insulin glargine; parenteral
1.3
11.0
719
5469
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.2
11.0
1494
12475
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
1.7
10.9
203
1175
XF400
NOMESCO Finland
ECG with 12 standard connections
0.8
10.9
1017
12413
R01AD12
ATC
fluticasone furoate; nasal
1.2
10.8
1586
13350
-1
NOMESCO Finland
NA
1.2
10.8
1997
17196
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
2.3
10.7
96
420
A10AE05
ATC
insulin detemir; parenteral
1.5
10.7
393
2696
S01XA18
ATC
ciclosporin; ophthalmic
3.3
10.7
52
158
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
10.6
3724
33804
SPAT1131
SPAT
Colonoscopy
1.6
10.6
256
1598
S01EB03
ATC
ecothiopate; ophthalmic
+∞
10.4
10
*
S01EXXX
ATC
NA
+∞
10.4
10
*
37500
ICD-8 Finland
Glaucoma, Primary, acute
+∞
10.4
10
*
WX723
NOMESCO Finland
CPAP therapy
1.8
10.4
185
1056
WX780
NOMESCO Finland
Remote monitoring CPAP
1.7
10.3
204
1202
0147
NOMESCO Finland
NA
23.3
10.2
14
6
ZXC50
NOMESCO Finland
Cryotherapy
1.6
10.2
276
1772
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
3.1
10.1
53
170
G04CA02
ATC
tamsulosin; oral
1.2
10.1
1972
17048
H36.00
ICD-10 Finland
Diabetic background retinopathy
2.2
10.1
104
484
H47.2
ICD-10 Finland
Optic atrophy
3.8
10.1
41
108
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
1.6
10.0
223
1363
3002
NOMESCO Finland
NA
39.9
9.9
12
*
CG2S4
NOMESCO Finland
Photography of cornea
3.5
9.9
44
125
H54.5
ICD-10 Finland
Severe visual impairment, monocular
3.5
9.8
44
126
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
4.3
9.8
35
82
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
7.0
9.7
23
33
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.2
9.7
2919
26149
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
1.7
9.7
207
1251
C08CA13
ATC
lercanidipine; oral
1.2
9.7
1195
9871
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
1.8
9.7
162
909
103
Kela drug reimbursment
Diabetes, insulin-treated
1.2
9.7
2386
21044
Z94.7
ICD-10 Finland
Corneal transplant status
3.4
9.6
44
128
H81
ICPC
Excessive ear wax
1.2
9.6
1429
12038
R4110
NOMESCO Finland
Physiotherapy
0.8
9.6
1618
18664
Z00.0
ICD-10 Finland
General medical examination
1.2
9.5
1383
11625
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.2
9.5
1212
10051
C09CA01
ATC
losartan; oral
1.2
9.4
2115
18495
CHF12
NOMESCO Finland
Endoscopic laser coagulation of ciliary body
99.9
9.4
10
*
HMAK
NOMESCO Finland
NA
1.3
9.4
684
5290
H40.2
ICD-10 Finland
Primary angle-closure glaucoma
+∞
9.4
9
*
CHB50
NOMESCO Finland
Trabeculotomy
+∞
9.4
9
*
37599
ICD-8 Finland
Glaucoma, Unspecified
+∞
9.4
9
*
SLT
NOMESCO Finland
NA
+∞
9.4
9
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.4
9.4
415
2961
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.4
9.3
503
3712
H91.1
ICD-10 Finland
Presbycusis
1.3
9.3
614
4680
R01AD09
ATC
mometasone; nasal
1.2
9.3
2924
26263
L17
ICPC
Foot/toe symptom/complaint
1.2
9.3
1963
17079
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.2
9.3
1531
13028
SPAT1097
SPAT
Recording of ECG
1.2
9.2
1294
10830
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.2
9.2
1504
12775
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
3.1
9.2
49
160
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
2.9
9.2
53
180
H10.5
ICD-10 Finland
Blepharoconjunctivitis
2.1
9.2
100
478
3793C
ICD-9 Finland
Other disorders of eye, Aphakia and other disorders of lens[PSEUDOPHAKIA]
2.9
9.2
54
188
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
13.6
9.1
15
11
H18.2
ICD-10 Finland
Other corneal oedema
4.7
9.0
29
62
XKD00
NOMESCO Finland
Uroflowmetry
1.2
9.0
1329
11187
QAA25
NOMESCO Finland
Destruction of lesion of head or neck
1.6
9.0
226
1429
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.3
8.9
651
5035
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.2
8.9
1404
11886
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.2
8.8
1060
8727
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.2
8.7
82
370
H04.3
ICD-10 Finland
Acute and unspecified inflammation of lacrimal passages
2.9
8.7
51
178
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.2
8.7
2220
19611
H52.0
ICD-10 Finland
Hypermetropia
2.0
8.6
103
512
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
3.8
8.6
35
93
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
2.6
8.6
59
224
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
3.2
8.5
43
136
SPAT1377
SPAT
Polysomnography
1.6
8.5
190
1166
H18.8
ICD-10 Finland
Other specified disorders of cornea
3.0
8.5
45
148
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
2.5
8.4
65
265
UDC00
NOMESCO Finland
Ear microscopy
1.3
8.4
507
3811
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.1
8.4
2804
25250
3656
FHL
Combined cataract glaucoma surgery
89.9
8.4
9
*
SPAT1281
SPAT
Other administrative function
1.3
8.3
564
4314
3650B
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AHDASKULMA)]
+∞
8.3
8
*
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
8.3
2614
23441
H33.3
ICD-10 Finland
Retinal breaks without detachment
1.5
8.3
233
1513
CBJ30
NOMESCO Finland
Plastic repair of levator aponeurosis of eyelid
2.9
8.3
48
165
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.3
8.3
548
4179
K85
ICPC
Elevated blood pressure
1.2
8.3
1306
11055
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
2.1
8.3
84
393
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
3.3
8.2
39
118
H35.8
ICD-10 Finland
Other specified retinal disorders
2.9
8.2
48
167
SPAT1101
SPAT
Orthostatic test
1.4
8.1
427
3142
R3120
NOMESCO Finland
Training in mobility skills
6.0
8.1
21
35
3623C
ICD-9 Finland
Other retinal disorders, Retinal vascular occlusion[OCCLUSIO VENAE CENTRALIS RETINAE]
17.1
8.1
12
7
G04CA01
ATC
alfuzosin; oral
1.2
8.0
867
7050
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
6.8
8.0
19
28
A10AE06
ATC
insulin degludec; parenteral
1.7
8.0
144
831
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
22.0
8.0
11
5
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
2.4
8.0
65
272
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
2.6
8.0
55
211
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
3.2
7.9
38
117
SAD01
NOMESCO Finland
Assessment of need for oral health care, standard
1.3
7.9
633
4967
D07AC01
ATC
betamethasone; topical
1.1
7.8
2605
23439
S06.0
ICD-10 Finland
Concussion
1.3
7.8
686
5442
XQ848
NOMESCO Finland
Dermatological photography
1.6
7.8
181
1123
Y0291
ICD-8 Finland
Examination of the nervous system and sensory organs, Eye
8.4
7.8
16
19
J01AA02
ATC
doxycycline; systemic
1.1
7.7
6686
63888
CWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in eye and adjacent structures
44.9
7.7
9
*
SDA02
NOMESCO Finland
Parodonthologic therapy
1.2
7.7
2067
18308
L60.0
ICD-10 Finland
Ingrowing nail
1.5
7.7
269
1835
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.4
7.6
320
2262
Z71.8
ICD-10 Finland
Other specified counselling
1.2
7.6
1510
13048
J05AB01
ATC
aciclovir; systemic
1.2
7.6
1461
12591
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
1.7
7.5
155
931
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
1.2
7.5
926
7641
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.2
7.5
1056
8834
Z01.2
ICD-10 Finland
Dental examination
1.1
7.5
2550
22963
L57.0
ICD-10 Finland
Actinic keratosis
1.2
7.5
934
7717
SPAT1053
SPAT
Memory test
1.2
7.5
1585
13772
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
2.9
7.5
41
139
XJH00
NOMESCO Finland
Transanal ultrasonography
1.3
7.5
512
3932
-1
SPAT
NA
1.6
7.4
195
1246
H3600, E113
ICD-10 Finland
NA
1.8
7.4
114
626
SAD02
NOMESCO Finland
Assessment of need for oral health care, extensive
1.7
7.4
157
951
S01GX08
ATC
ketotifen; ophthalmic
1.6
7.4
178
1115
H33.4
ICD-10 Finland
Traction detachment of retina
4.5
7.3
24
53
3652A
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[AKUUTTI AHDASKULMAGLAUKOOMA]
+∞
7.3
7
*
37513
ICD-8 Finland
Glaucoma, Chronicum pigmentosum
+∞
7.3
7
*
37703
ICD-8 Finland
Other diseases of retina and optic nerve, Thrombosis venae centralis retinae
9.3
7.3
14
15
R53
ICD-10 Finland
Malaise and fatigue
1.2
7.2
1647
14395
R00.1
ICD-10 Finland
Bradycardia, unspecified
1.4
7.2
283
1979
H35.7
ICD-10 Finland
Separation of retinal layers
2.4
7.1
57
239
C10AA07
ATC
rosuvastatin; oral
1.2
7.1
1950
17281
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.1
7.1
3097
28331
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
4.8
7.1
22
46
CBB30
NOMESCO Finland
Excision of lesion of eyelid
1.5
7.1
228
1531
SPAT1211
SPAT
Application of soft bandage
1.3
7.1
682
5473
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.3
7.1
592
4669
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
1.4
7.1
297
2103
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
7.1
1600
13970
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.4
7.0
345
2512
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.1
7.0
2102
18747
SPAT1352
SPAT
Inspection, maintenance and instruction for use of hearing aid
1.7
7.0
138
819
H02.1
ICD-10 Finland
Ectropion of eyelid
1.8
7.0
103
558
H47.0
ICD-10 Finland
Disorders of optic nerve, not elsewhere classified
2.7
6.9
45
168
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
2.2
6.9
67
310
Z97.4
ICD-10 Finland
Presence of external hearing-aid
1.3
6.9
426
3220
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
2.2
6.9
62
278
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
4.2
6.9
24
57
H3601, E113
ICD-10 Finland
NA
1.7
6.8
124
722
N17
ICPC
Vertigo/dizziness
1.2
6.8
897
7457
R06AX27
ATC
desloratadine; oral
1.2
6.8
1415
12269
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
3.1
6.8
34
109
J01FF01
ATC
clindamycin; systemic
1.2
6.8
1928
17130
I49.5
ICD-10 Finland
Sick sinus syndrome
1.4
6.8
373
2774
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
0.7
6.8
201
2871
XCH00
SPAT
NA
39.9
6.7
8
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.2
6.7
835
6898
H11.3
ICD-10 Finland
Conjunctival haemorrhage
1.4
6.7
284
2017
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
3.7
6.7
27
73
N03AX12
ATC
gabapentin; oral
1.2
6.7
1087
9224
L03
ICPC
Low back symptom/complaint
1.2
6.7
1688
14866
F28
ICPC
Limited function/disability (F)
2.4
6.6
52
218
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
3.4
6.6
29
84
130
Kela drug reimbursment
Malignant tumour
0.8
6.6
426
5429
CK2K4
NOMESCO Finland
Red-free imaging of ocular fundus
4.4
6.6
22
50
NH3EA
NOMESCO Finland
Feet X-ray examination with load
1.7
6.6
122
714
M79.6
ICD-10 Finland
Pain in limb
1.1
6.6
2697
24546
M54.5
ICD-10 Finland
Low back pain
1.1
6.6
2231
20063
CKC60
NOMESCO Finland
Local buckling of sclera using implant
2.6
6.5
44
170
S01GX05
ATC
lodoxamide; ophthalmic
1.9
6.5
91
485
H10.4
ICD-10 Finland
Chronic conjunctivitis
2.3
6.5
57
252
VALMI
NOMESCO Finland
NA
1.2
6.5
1369
11878
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
1.3
6.5
601
4799
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
2.6
6.5
43
164
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.2
6.5
729
5958
CKD50
NOMESCO Finland
Endodiathermy of retina
4.3
6.5
22
51
SPAT1254
SPAT
Administration of medicine
1.2
6.5
1219
10481
WX144
NOMESCO Finland
Subconjunctival anesthesy
1.8
6.4
100
553
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
1.4
6.4
253
1771
A44
ICPC
General and Unspecified, Preventive immunization/medic
1.3
6.4
501
3918
N06AX11
ATC
mirtazapine; oral
1.1
6.4
2335
21094
SCA03
NOMESCO Finland
Preventive oral health care, extensive
1.5
6.4
212
1439
S94
ICPC
Ingrowing nail
1.8
6.4
101
562
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
1.8
6.4
94
514
SAA03
NOMESCO Finland
Extended examination of mouth
1.1
6.4
2318
20935
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.1
6.3
3835
35704
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.2
6.3
1314
11393
3643
FHL
Vitrectomy through pars Plana
4.5
6.2
20
44
CHF30
NOMESCO Finland
Cyclodialysis
+∞
6.2
6
*
3651X
ICD-9 Finland
Glaucoma, Open-angle glaucoma[AVOKULMAGLAUKOOMA MUU]
+∞
6.2
6
*
S01EB51
ATC
pilocarpine, combinations; ophthalmic
+∞
6.2
6
*
3656C
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA NEOVASCULARE]
+∞
6.2
6
*
74420
ICD-8 Finland
Congenital anomalies of eye, Buphthalmus (glaucoma)
+∞
6.2
6
*
A02BC05
ATC
esomeprazole; systemic
1.1
6.2
3189
29404
F27
ICPC
Fear of eye disease
2.1
6.2
67
325
CHC10
NOMESCO Finland
Peripheral iridectomy
26.6
6.2
8
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
6.2
1153
9908
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
1.5
6.2
211
1440
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.2
6.2
1225
10582
H30.2
ICD-10 Finland
Posterior cyclitis
4.1
6.2
22
54
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.1
6.1
3819
35589
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
5.3
6.1
17
32
S01BA09
ATC
clobetasone; ophthalmic
5.3
6.1
17
32
37002
ICD-8 Finland
Refractive errors, Myopia
5.3
6.1
17
32
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.2
6.1
1156
9939
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
2.5
6.1
44
176
R06AE07
ATC
cetirizine; oral
1.1
6.1
2970
27294
3792A
ICD-9 Finland
Other disorders of eye, Disorders of vitreous body
7.6
6.1
13
17
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
1.4
6.1
271
1944
DFF00
NOMESCO Finland
Pure tone audiometry
1.2
6.1
677
5527
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
1.3
6.1
340
2537
M48.0
ICD-10 Finland
Spinal stenosis
1.2
6.1
1069
9137
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
4.0
6.0
22
55
RD211
NOMESCO Finland
NA
1.4
6.0
277
1998
WX199
NOMESCO Finland
Other local analgesia
1.5
6.0
193
1300
S05.0
ICD-10 Finland
Injury of conjunctiva and corneal abrasion without mention of foreign body
1.8
6.0
93
517
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
6.7
6.0
14
21

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
10003
91448
1.90
89.36
21.0
21.1
4.0
4.0
mmol/l
2.15
9675
88795
9983
91308
1.88
87.59
20.8
20.9
139.6
139.6
mmol/l
0.06
9666
88811
10118
93259
1.90
82.00
25.8
25.8
30.5
30.4
pg
3.88
9884
91385
10118
93262
1.90
81.94
25.9
25.8
92.0
91.7
fl
7.56
9885
91392
10118
93266
1.90
81.87
26.0
25.9
4.4
4.4
e12/l
2.88
9721
89806
10119
93279
1.90
81.86
26.2
26.1
131.8
132.0
g/l
0.41
9888
91429
10116
93245
1.90
81.82
26.0
25.9
241.8
243.8
e9/l
2.31
9769
90174
10118
93282
1.90
81.59
26.0
25.9
6.9
6.9
e9/l
0.14
9714
89841
1303
7567
1.81
79.36
4.5
4.6
—
—
—
0
0
9886
90781
1.77
76.88
11.5
11.5
24.1
24.5
u/l
0.65
9331
86601
3317
24493
1.50
76.28
4.7
4.7
0.0
0.0
estimate
0.13
1273
7715
9887
90872
1.76
75.58
20.8
20.9
82.1
81.9
umol/l
0.14
9882
90831
9596
87699
1.66
72.23
17.7
16.8
—
—
—
0
0
9036
81493
1.56
70.86
6.9
6.6
41.5
40.9
mmol/mol
8.01
7998
73491
9379
85568
1.59
67.16
5.6
5.4
2.6
2.6
mmol/l
4.77
8202
76588
9293
84640
1.58
66.62
5.3
5.2
6.2
6.1
mmol/l
5.84
8025
75023
8800
79524
1.50
62.14
5.2
5.0
2.4
2.1
mu/l
0.44
7681
70917
9120
83056
1.53
61.78
5.0
4.8
4.5
4.5
mmol/l
5.24
8019
74587
9023
82199
1.50
58.88
5.0
4.7
1.5
1.5
mmol/l
0.48
7850
73253
9407
86628
1.54
56.52
17.4
17.6
25.7
26.5
mg/l
1.30
7679
71163
2953
22348
1.43
56.17
1.8
1.7
17259999.4
26741751.0
pmol/l
0.68
2277
17774
7237
63654
1.38
54.74
4.5
4.4
—
—
—
0
0
2959
22543
1.42
53.79
4.1
4.0
—
—
—
0
0
1334
8689
1.60
51.69
4.1
3.9
1.2
1.2
mmol/l
0.20
1134
7446
7622
68088
1.37
49.11
20.5
21.5
13.9
13.9
%
4.34
7424
66459
8699
79489
1.42
48.52
4.4
4.2
1.3
1.3
mmol/l
1.37
7484
70029
7379
65912
1.35
45.34
4.3
4.1
15.1
15.1
pmol/l
0.15
6359
58352
2299
17248
1.42
44.10
4.7
4.6
—
—
—
0
0
4728
39837
1.32
42.58
4.4
4.2
60.8
76.4
ng/l
0.40
3741
30591
7445
66854
1.34
42.44
4.5
4.3
14.4
14.9
mm/h
1.56
6665
60769
2926
22976
1.37
42.42
3.5
3.3
—
—
—
0
0
7929
72006
1.34
40.94
7.4
7.7
79.6
80.9
u/l
1.41
7339
67190
4590
38755
1.31
39.77
11.9
10.4
0.0
0.0
e9/l
0.59
3913
31440
5187
44806
1.29
36.74
4.4
4.2
0.0
0.0
estimate
0.50
1354
8053
5217
45481
1.27
32.84
4.5
4.3
0.0
0.0
estimate
0.49
1317
7966
5157
44927
1.27
32.52
5.7
5.7
0.0
0.0
estimate
0.80
1342
8058
1026
6996
1.51
31.58
4.0
3.9
0.0
0.4
%
2.87
241
1907
2818
22931
1.30
29.92
1.7
1.6
1.3
1.3
mmol/l
0.16
2150
18857
7006
63683
1.26
29.39
5.4
5.3
1023.2
1926.1
e6/l
1.31
92
1017
4934
43150
1.25
28.71
11.8
10.7
1.3
1.3
inr
0.57
1741
11328
1075
7539
1.47
28.68
4.1
3.9
0.2
0.1
%
0.50
270
2268
1121
7950
1.45
28.19
4.0
3.9
0.9
0.9
%
0.01
290
2444
7057
64355
1.26
28.02
5.0
4.9
—
—
—
0
0
1022
7178
1.46
26.99
4.0
3.7
0.5
0.7
%
0.78
217
1732
6306
57041
1.24
25.75
4.8
4.7
6.9
6.9
mmol/l
0.90
5928
53624
463
2752
1.71
25.24
4.6
4.0
7.4
7.4
ph
3.12
383
2330
3538
30193
1.25
24.34
3.4
3.2
445.1
400.2
mg/l
0.21
2166
18672
397
2290
1.76
24.10
2.5
2.6
16.2
15.7
%
1.30
200
1219
3718
31957
1.24
23.84
4.3
3.9
10.5
9.2
mg/mmol
0.86
2249
19578
5767
52063
1.22
22.52
6.4
6.6
1.2
1.2
mmol/l
0.03
4581
43469
3557
30569
1.24
22.50
3.4
3.1
6.8
6.9
mmol/l
0.82
2855
24946
307
1686
1.84
21.99
1.9
1.9
1.9
1.7
mmol/l
1.59
302
1645
3524
30405
1.23
21.14
4.4
4.4
—
—
—
0
0
4080
35771
1.22
20.81
2.9
2.9
152.0
155.2
ug/l
0.25
3561
32141
7888
73835
1.23
20.11
18.4
19.3
38.4
38.2
%
0.31
4245
45286
3485
30155
1.22
20.07
2.6
2.5
62.3
59.7
u/l
0.71
3151
27541
4384
38816
1.21
19.96
2.3
2.2
80.8
80.3
nmol/l
0.62
3768
33606
393
2394
1.66
19.58
4.8
4.1
2.4
2.8
mmol/l
1.59
267
1667
393
2395
1.66
19.55
4.8
4.1
5.0
5.0
kpa
0.08
383
2328
395
2411
1.66
19.53
4.8
4.2
8.6
8.3
kpa
1.57
385
2343
3505
30451
1.22
19.17
5.6
5.5
5.0
4.0
ug/l
0.29
3029
26887
4920
44282
1.19
18.15
4.4
4.6
34.5
34.5
g/l
0.12
4478
40546
2694
22967
1.22
17.45
1.9
1.8
1248.2
1158.2
nmol/l
5.29
1968
16883
5212
47265
1.19
17.34
5.6
5.9
1.2
1.2
mmol/l
1.70
4606
42160
2546
21617
1.23
17.10
2.8
2.7
6.1
5.4
e6/l
1.25
2228
18862
3536
31015
1.20
16.99
4.0
4.0
7.4
7.4
ph
3.38
932
5641
3066
26537
1.21
16.96
2.4
2.3
3.1
3.1
mg/l
0.22
2563
22386
3891
34611
1.19
15.64
3.2
3.2
1816.9
1779.9
ng/l
0.17
3329
30027
1379
11099
1.27
14.70
1.8
1.8
—
—
—
0
0
5499
50507
1.17
14.62
5.5
6.1
11.8
11.9
umol/l
0.16
5131
47726
3530
31300
1.18
14.41
2.2
2.1
184.4
216.7
u/l
1.66
3249
29027
3894
34880
1.18
13.95
3.0
3.3
2.4
2.4
mmol/l
1.30
3305
29397
3851
34478
1.18
13.85
3.6
3.6
—
—
—
0
0
986
7690
1.31
13.39
2.0
2.2
396.6
384.0
nmol/l
0.55
883
6947
1916
16265
1.21
12.37
1.3
1.2
1.6
1.8
u/ml
0.22
519
3868
5489
50795
1.15
12.26
3.1
3.1
53.0
54.8
u/l
0.65
4894
45756
2365
20501
1.19
12.16
3.0
3.0
521.4
540.0
mosm/kgh2o
4.50
2032
17355
3553
31852
1.17
12.15
5.4
5.6
—
—
—
0
0
2932
25922
1.17
11.90
1.6
1.6
20.9
20.5
nmol/l
0.73
2409
21741
358
2405
1.50
11.83
4.1
3.7
—
—
—
0
0
4771
43844
1.15
11.44
2.1
2.1
94.2
94.1
pmol/l
0.06
2306
22216
2754
24298
1.17
11.37
4.8
4.7
22.4
22.3
%
0.05
1490
13020
4839
44685
1.14
10.47
5.5
5.6
0.0
0.0
e9/l
0.55
4197
37785
4971
46027
1.14
10.25
5.6
5.8
0.2
0.2
e9/l
0.78
4360
39429
4801
44389
1.14
10.05
5.5
5.6
0.6
0.6
e9/l
0.88
4165
37492
264
1732
1.53
9.83
3.5
3.0
—
—
—
0
0
92
446
2.07
9.76
2.2
2.2
1871.4
1809.1
ml
0.24
74
369
4894
45402
1.13
9.54
5.6
5.7
1.9
1.9
e9/l
0.12
4309
39014
588
4501
1.32
9.16
1.3
1.3
—
—
—
0
0
1505
12871
1.19
8.75
8.0
8.4
—
—
—
0
0
256
1726
1.49
8.44
3.5
3.1
4.2
4.4
e9/l
0.83
256
1720
5544
52124
1.12
8.14
8.3
8.8
4.3
4.3
e9/l
0.39
4856
44919
934
7679
1.23
8.14
1.5
1.6
—
—
—
0
0
1188
10008
1.21
8.12
1.3
1.3
—
—
—
0
0
4393
40819
1.12
7.78
5.9
5.9
0.7
0.7
%
1.90
4067
37528
116
660
1.76
7.69
1.8
1.5
—
—
—
0
0
3113
28352
1.13
7.68
3.3
3.4
0.4
0.5
e6/l
0.77
2448
21501
348
2532
1.38
7.62
2.2
2.3
127.2
126.3
g/l
0.23
278
1807
3265
29840
1.13
7.60
4.2
4.3
—
—
—
0
0
4501
41932
1.12
7.54
5.9
5.9
2.9
2.8
%
1.91
4159
38521
4592
42849
1.12
7.45
6.0
6.1
25.9
26.1
%
0.74
4238
39223
2243
20028
1.15
7.44
5.0
4.8
1.0
1.0
kg/l
0.65
418
3191
1951
17253
1.16
7.41
3.3
3.3
0.8
0.8
ug/l
0.34
1395
12460
4521
42157
1.12
7.41
6.2
6.2
9.0
8.8
%
1.72
4196
38864
4520
42152
1.12
7.39
5.8
5.8
59.1
58.6
%
1.40
4177
38790
2974
27125
1.13
7.05
3.3
3.3
—
—
—
0
0
57
264
2.16
6.92
1.2
1.2
—
—
—
0
0
335
2463
1.37
6.92
2.3
2.3
136.1
99.1
ug/min
0.68
176
1390
3341
30800
1.12
6.49
3.5
3.5
144.1
101.4
e6/l
0.46
2673
23694
820
6822
1.22
6.39
6.3
6.6
24.4
24.7
mmol/l
1.09
765
6358
3781
35122
1.11
6.37
4.0
4.0
115.3
128.1
e6/l
0.39
2856
25264
306
2250
1.37
6.35
2.9
2.6
1.8
1.8
mg/l
0.08
277
1987
325
2424
1.35
6.17
2.8
3.0
8.2
7.8
kpa
3.51
302
2242
369
2807
1.32
6.13
3.1
3.2
24.6
25.1
mmol/l
0.95
328
2455
379
2894
1.32
6.13
3.7
3.2
—
—
—
0
0
286
2098
1.37
6.05
2.8
2.9
—
—
—
0
0
13
27
4.81
5.95
1.1
1.1
0.0
0.0
g/l
—
5
13
1533
13550
1.15
5.79
1.3
1.3
36.9
40.7
iu/ml
0.41
500
4161
867
7333
1.19
5.70
4.2
4.5
—
—
—
0
0
743
6202
1.21
5.63
3.0
2.8
10.5
10.5
g/l
0.05
663
5631
1605
14266
1.14
5.58
1.6
1.5
2.6
2.6
g/l
0.01
901
7797
2259
20516
1.12
5.58
2.8
3.1
2.5
2.5
mmol/l
1.51
1981
17725
1472
13007
1.15
5.58
1.3
1.2
—
—
—
0
0
1185
10312
1.16
5.53
1.4
1.4
—
—
—
0
0
1163
10124
1.16
5.40
2.5
2.4
6.6
6.5
ug/l
0.06
969
8516
219
1570
1.40
5.37
1.1
1.0
—
—
—
0
0
2691
24735
1.11
5.34
2.9
2.8
5336.4
6295.5
umol/l
0.51
2235
20701
1838
16527
1.13
5.34
2.6
2.5
12.1
11.9
umol/l
0.46
1643
15062
3901
36544
1.10
5.32
2.2
2.3
—
—
—
0
0
46
220
2.09
5.24
1.2
1.1
1740.8
1599.8
miu/ml
0.39
46
220
2320
21171
1.12
5.24
1.4
1.3
—
—
—
0
0
719
6035
1.20
5.16
5.7
6.2
24.4
24.9
mmol/l
3.11
708
5967
89
532
1.67
5.10
1.1
1.1
—
—
—
0
0
405
3208
1.27
5.02
4.4
5.9
1.3
1.4
mmol/l
1.27
360
2835
529
4322
1.23
4.99
4.8
4.5
—
—
—
0
0
2146
19547
1.12
4.99
1.8
1.7
1.5
1.5
mg/l
0.36
1642
15272
477
3864
1.24
4.88
3.4
3.1
47.3
51.6
mg/l
0.12
355
3146
13
32
4.06
4.87
1.1
1.1
0.0
0.0
g/l
—
5
11
477
3873
1.24
4.78
3.4
3.1
55.4
81.1
mg/l
0.85
356
3148
754
8805
0.84
4.77
2.3
2.4
35.6
48.2
u/l
0.80
633
7474
464
3757
1.24
4.77
3.4
3.0
3.6
3.0
ratio
0.22
41
271
216
1579
1.37
4.76
2.8
2.7
—
—
—
0
0
1126
9881
1.15
4.70
2.8
2.5
68.0
68.4
e9/l
0.17
907
7508
285
2177
1.31
4.69
1.9
1.8
10.4
12.2
mg/l
2.53
257
1972
204
1500
1.36
4.37
1.2
1.4
—
—
—
0
0
40
196
2.04
4.34
1.1
1.1
—
—
—
0
0
113
750
1.51
4.24
1.3
1.4
2.9
2.9
g/l
0.00
68
524
113
750
1.51
4.24
1.3
1.4
6.3
7.0
g/l
1.45
68
519
113
750
1.51
4.24
1.3
1.4
0.3
0.4
g/l
2.97
68
523
90
571
1.58
4.14
1.3
1.3
—
—
—
0
0
112
750
1.50
4.05
1.3
1.4
—
—
—
0
0
118
1694
0.69
3.89
3.1
3.5
42.9
39.1
u/ml
0.10
112
1637
1508
13649
1.12
3.89
5.0
5.2
1.0
1.0
mmol/l
0.63
1392
12439
1686
15363
1.11
3.84
2.6
2.5
2.3
2.3
g/l
0.49
1499
14014
1167
10416
1.13
3.81
1.3
1.3
547.9
517.5
titre
0.21
252
2396
57
331
1.72
3.73
1.1
1.1
1.1
1.1
ratio
0.86
22
98
1592
14486
1.11
3.73
2.6
2.6
21.6
21.1
%
0.70
1276
12136
575
4886
1.18
3.68
2.0
1.9
1.2
1.4
g/l
1.11
504
4344
522
4411
1.19
3.57
1.2
1.2
—
—
—
0
0
82
530
1.55
3.54
2.2
2.3
—
—
—
0
0
907
8006
1.14
3.53
2.4
2.3
—
—
—
0
0
80
515
1.55
3.52
1.1
1.1
—
—
—
0
0
4536
43313
1.08
3.51
4.2
4.2
—
—
—
0
0
33
165
2.00
3.46
1.3
1.5
—
—
—
0
0
682
5909
1.16
3.45
2.5
2.5
—
—
—
0
0
129
919
1.41
3.43
1.9
1.9
0.8
0.7
g/24h
—
5
31
377
3106
1.22
3.40
1.2
1.1
196.7
172.2
titre
—
9
63
1062
9506
1.13
3.33
2.4
2.5
66.3
65.9
g/l
1.26
950
8404
2216
23668
0.92
3.23
2.4
2.5
—
—
—
0
0
159
1188
1.34
3.19
1.5
1.6
0.7
0.8
g/l
1.39
105
883
457
3861
1.19
3.18
4.2
3.7
1.3
1.4
mmol/l
1.17
450
3794
496
5775
0.85
3.12
8.1
7.8
24.0
24.4
mmol/l
2.81
450
5324
971
8682
1.13
3.11
3.9
3.7
—
—
—
0
0
568
4899
1.17
3.08
3.0
3.2
4.3
4.3
pmol/l
0.55
487
4224
25
118
2.12
3.07
2.7
2.7
5.6
7.0
mg/l
0.71
17
94
72
469
1.54
3.06
1.5
1.5
3.2
3.8
%
0.14
14
108
74
486
1.52
3.03
2.6
2.0
9.6
9.1
mmol/l
0.61
53
373
760
6711
1.14
2.98
3.5
3.7
7.4
7.4
ph
0.57
149
842
82
553
1.48
2.97
2.2
2.2
—
—
—
0
0
309
2536
1.22
2.94
1.6
1.6
—
—
—
0
0
488
4181
1.17
2.90
1.3
1.3
175.6
230.0
u/ml
1.42
444
3790
353
2941
1.20
2.89
1.5
1.4
251.8
267.6
ug/g
0.81
207
1774
768
6801
1.14
2.89
3.5
3.7
5.2
5.2
kpa
0.18
695
6224
270
3298
0.81
2.89
3.8
3.5
—
—
—
0
0
45
265
1.70
2.88
1.2
1.1
—
—
—
0
0
250
2015
1.24
2.84
1.4
1.4
—
—
—
0
0
524
4529
1.16
2.80
4.3
4.9
0.9
0.9
%
0.08
486
4255
282
2308
1.22
2.78
5.1
6.7
105.3
105.0
mmol/l
0.43
254
2061
282
2308
1.22
2.78
5.1
6.7
11.4
11.2
mmol/l
0.41
254
2061
145
1095
1.33
2.76
4.7
4.1
351.3
343.4
umol/l
0.26
120
901
941
8467
1.12
2.74
3.5
3.5
97.3
94.7
ng/l
0.31
748
7057
359
3017
1.19
2.70
1.3
1.2
0.8
1.0
u/ml
0.21
40
291
2277
24127
0.93
2.69
3.6
4.0
85.6
85.5
%
0.04
2215
23529
973
8793
1.11
2.63
2.2
2.0
145.2
161.3
ug/g
0.72
720
6724
59
384
1.54
2.57
1.4
1.5
3.1
2.5
%
0.17
44
327
387
3290
1.18
2.57
4.5
4.0
3.8
3.9
mmol/l
1.31
364
3084
88
621
1.42
2.57
1.3
1.6
—
—
—
0
0
83
581
1.43
2.54
2.1
2.1
493.7
496.5
min
0.10
52
415
536
4680
1.15
2.53
1.9
1.9
2.3
2.4
ug/l
0.06
455
4043
1383
12757
1.09
2.48
1.3
1.2
14.2
15.8
u/ml
0.31
516
4311
79
1107
0.71
2.42
1.3
1.2
—
—
—
0
0
1137
10409
1.10
2.40
3.3
3.0
218.4
241.0
ng/l
1.22
1040
9570
70
480
1.46
2.40
1.1
1.1
1.4
9.3
nmol/l
1.70
16
108
435
4996
0.86
2.37
4.4
3.7
24.0
24.2
mmol/l
0.68
395
4467
143
1106
1.29
2.35
1.3
1.3
—
—
nmol/l
—
0
0
281
2346
1.20
2.33
1.7
1.6
—
—
—
0
0
233
1912
1.22
2.31
1.6
1.6
4.3
5.0
iu/l
0.36
61
605
524
4603
1.14
2.29
4.3
4.9
1.6
1.6
%
0.13
490
4326
51
331
1.54
2.29
1.5
1.4
27.8
18.4
%
1.29
44
303
641
5706
1.13
2.28
1.2
1.2
—
—
—
0
0
808
8895
0.90
2.25
7.4
7.1
—
—
—
0
0
111
836
1.33
2.22
2.2
2.2
711.2
638.7
ml
0.55
65
540
66
456
1.45
2.21
1.4
1.4
63.7
65.8
%
0.16
48
375
5
9
5.54
2.21
1.0
1.3
—
—
—
0
0
1410
13088
1.09
2.20
2.4
2.3
1.8
1.8
%
0.15
1215
11357
45
287
1.57
2.19
1.0
1.0
—
—
—
0
0
35
559
0.62
2.11
2.3
1.4
—
—
—
0
0
70
495
1.41
2.09
1.3
1.3
1.1
1.1
promille
0.01
55
370
129
1004
1.29
2.06
1.6
1.3
277.7
276.0
mosm/kgh2o
0.31
102
738
36
566
0.63
2.03
2.4
1.4
—
—
—
0
0
30
177
1.69
2.00
1.2
1.1
—
—
—
0
0
1560
16580
0.93
1.99
3.1
3.1
2.0
2.9
e6/l
5.00
890
9135
1704
16000
1.07
1.99
2.0
1.9
30.5
30.0
s
1.52
1649
15506
36
562
0.64
1.98
2.4
1.4
—
—
—
0
0
26
148
1.75
1.96
1.1
1.1
—
—
—
0
0
28
163
1.72
1.96
5.4
4.9
—
—
—
0
0
86
638
1.35
1.95
2.7
2.5
7.4
7.4
ph
0.14
40
239
28
164
1.71
1.92
1.1
1.0
—
—
—
0
0
212
2530
0.83
1.91
1.3
1.4
—
—
—
0
0
38
243
1.56
1.87
48.6
30.3
7.6
7.1
ug/l
0.65
38
212
40
260
1.54
1.84
2.2
1.8
—
—
—
0
0
23
129
1.78
1.83
1.7
1.7
10.5
8.9
mg/l
0.77
15
100
196
1624
1.21
1.83
1.5
1.3
17.1
33.2
e6/l
0.76
155
1262
196
1625
1.21
1.82
1.6
1.4
1101.4
986.0
e6/l
0.07
168
1328
36
550
0.65
1.82
2.4
1.4
—
—
—
0
0
157
1275
1.23
1.79
6.1
13.0
7.7
7.4
mmol/l
0.41
135
1030
658
5963
1.11
1.77
1.2
1.2
—
—
—
0
0
1691
17839
0.94
1.75
2.9
2.9
1.1
1.3
e6/l
1.46
1016
10307
2990
31014
0.95
1.75
2.4
2.5
—
—
—
0
0
237
2010
1.18
1.73
1.2
1.3
9.2
5.7
u/ml
0.42
37
346
34
517
0.66
1.70
2.4
1.4
—
—
—
0
0
146
1188
1.23
1.66
1.8
1.9
—
—
—
0
0
251
2149
1.17
1.65
1.2
1.2
25.7
44.0
u/ml
—
9
123
176
2102
0.83
1.64
1.2
1.2
—
—
—
0
0
471
4213
1.12
1.63
1.4
1.5
17.9
21.3
u/ml
—
9
101
1472
13860
1.07
1.61
2.1
2.0
—
—
—
0
0
34
221
1.54
1.60
1.1
1.0
—
—
—
0
0
117
934
1.25
1.60
1.2
1.2
336.6
321.5
nmol/l
0.32
92
709
145
1187
1.22
1.58
2.9
2.6
—
—
—
0
0
14
70
2.00
1.58
1.1
1.1
—
—
—
0
0
68
506
1.34
1.57
1.2
1.3
1.4
1.4
u/ml
0.00
39
278
96
750
1.28
1.57
2.1
2.0
1.0
1.1
e9/l
0.47
57
464
22
129
1.70
1.55
1.6
1.5
—
—
—
0
0
28
433
0.64
1.54
2.4
1.5
—
—
—
0
0
2806
26966
1.05
1.52
3.2
3.2
35.0
35.6
u/l
0.13
2600
25268
654
5978
1.10
1.52
3.0
3.3
4.3
4.1
e9/l
0.67
445
4197
232
1991
1.17
1.51
1.2
1.2
12.1
5.6
u/ml
0.30
23
225
82
632
1.30
1.50
13.2
10.9
—
—
—
0
0
214
1827
1.17
1.49
1.1
1.1
4.7
12.7
u/ml
—
9
118
154
1278
1.21
1.48
1.3
1.3
0.6
1.9
nmol/l
0.74
143
1220
9
37
2.43
1.47
1.0
1.5
—
—
—
0
0
1081
10105
1.07
1.47
6.5
7.0
119.6
119.2
g/l
0.25
1037
9735
196
1664
1.18
1.47
1.3
1.2
4.0
3.9
mmol/l
0.59
186
1543
90
705
1.28
1.46
2.4
1.8
11.1
10.6
%
0.54
90
705
94
741
1.27
1.45
1.2
1.3
1.3
1.5
nmol/l
0.65
86
662
222
1906
1.17
1.45
1.4
1.3
566.8
566.8
mg/l
0.00
214
1789
5
16
3.12
1.43
1.0
1.0
—
—
—
0
0
118
957
1.23
1.43
1.3
1.2
73.3
55.2
u/ml
0.38
11
72
57
421
1.35
1.41
1.1
1.1
45.0
43.8
mg/l
0.05
46
362
42
295
1.42
1.39
1.2
1.1
—
—
—
0
0
13
67
1.94
1.37
1.3
1.6
—
—
—
0
0
174
1473
1.18
1.37
1.2
1.2
34.4
50.1
u/ml
0.77
20
173
317
3560
0.89
1.36
2.1
2.1
37.3
37.0
g/l
0.35
252
2934
85
668
1.27
1.36
1.2
1.2
—
—
—
0
0
185
1575
1.17
1.36
1.6
1.5
—
—
—
0
0
118
964
1.22
1.35
1.7
1.5
28.1
29.2
%
0.11
58
599
153
1284
1.19
1.33
1.3
1.3
0.2
0.3
nmol/l
0.71
13
103
1186
11168
1.07
1.33
6.2
6.6
95.5
95.3
%
0.21
1140
10719
27
175
1.54
1.32
1.4
1.2
—
—
—
0
0
599
5498
1.09
1.31
3.0
2.9
0.3
0.3
e6/l
0.19
585
5386
1738
16561
1.06
1.31
2.8
2.9
0.8
0.8
mmol/l
1.71
1572
15204
46
333
1.38
1.30
1.2
1.1
2259.9
600.1
ng/l
0.37
17
89
72
558
1.29
1.30
2.1
2.0
—
—
—
0
0
86
682
1.26
1.30
1.0
1.0
689.3
687.7
ng/l
0.01
56
436
27
176
1.53
1.30
1.0
1.0
—
—
—
0
0
285
3208
0.88
1.29
4.8
4.9
—
—
—
0
0
80
631
1.27
1.27
1.2
1.6
—
1542.9
—
0
14
354
3928
0.90
1.26
2.8
3.2
8915.3
1785.2
u/ml
0.48
303
3319
23
352
0.65
1.26
3.2
2.1
—
—
—
0
0
494
4505
1.10
1.26
2.9
2.8
—
—
—
0
0
198
2279
0.86
1.25
2.5
2.4
—
—
—
0
0
1015
10756
0.94
1.25
2.5
2.6
9.4
9.1
umol/l
0.14
861
9324
518
5635
0.91
1.25
3.9
4.1
—
—
—
0
0
26
170
1.53
1.24
1.0
1.1
—
—
—
0
0
17
278
0.61
1.24
3.5
1.7
—
—
—
0
0
28
187
1.50
1.22
3.3
2.5
14.8
14.7
ml/dl
0.05
23
175
53
399
1.33
1.20
1.1
1.1
319.5
292.9
mg/l
0.32
45
350
69
539
1.28
1.20
2.4
2.0
15.0
31.4
umol/l
—
8
55
151
1282
1.18
1.19
1.7
1.5
67.4
60.6
%
1.26
80
804
40
289
1.38
1.17
1.2
1.2
—
—
—
0
0
49
646
0.76
1.17
2.2
2.2
—
—
—
0
0
237
2087
1.14
1.15
1.3
1.3
—
—
—
0
0
1173
11100
1.06
1.15
4.1
4.5
—
—
—
0
0
85
685
1.24
1.15
1.0
1.0
437.1
333.6
ng/l
0.60
56
453
0
35
0.00
1.15
0.0
1.1
—
274.9
—
0
35
51
385
1.32
1.14
2.6
2.6
—
—
—
0
0
259
2295
1.13
1.14
1.1
1.1
—
—
—
0
0
79
632
1.25
1.14
1.1
1.1
—
—
—
0
0
94
767
1.22
1.14
1.4
1.3
—
—
—
0
0
34
242
1.40
1.10
1.2
1.4
—
—
—
0
0
239
2115
1.13
1.09
1.4
1.3
60.6
61.4
mmol/l
0.13
190
1687
562
5197
1.08
1.08
2.5
2.4
30.3
27.8
au/ml
0.10
15
159
13
218
0.59
1.07
1.2
1.2
—
—
—
0
0
45
338
1.33
1.06
2.0
1.9
—
—
—
0
0
129
1095
1.18
1.05
1.1
1.1
—
—
—
0
0
507
4676
1.09
1.05
1.3
1.3
52.0
54.0
au/ml
0.06
20
186
9
45
2.00
1.04
1.0
1.4
—
—
—
0
0
525
4851
1.08
1.04
2.1
2.1
12.2
11.6
nmol/l
0.68
443
4143
1312
12500
1.05
1.03
6.0
6.3
1.1
1.2
mmol/l
0.31
975
9781
138
1183
1.17
1.01
1.3
1.3
—
—
—
0
0
34
247
1.37
1.00
3.5
2.2
7.2
7.6
mmol/l
0.28
22
167
7
131
0.53
0.98
1.4
1.6
—
—
—
0
0
18
115
1.56
0.98
1.1
1.1
27.4
50.7
%
—
5
52
459
4232
1.09
0.97
1.2
1.2
135.3
133.8
iu/ml
0.03
162
1429
33
446
0.74
0.97
1.2
1.3
31.2
37.0
u/l
0.38
26
360
123
1049
1.17
0.97
1.1
1.3
—
—
—
0
0
594
5535
1.07
0.96
3.7
3.4
25.1
25.2
mmol/l
0.53
567
5380
36
266
1.35
0.96
1.5
1.4
—
—
—
0
0
55
434
1.27
0.93
1.1
1.1
—
—
—
0
0
38
285
1.33
0.93
1.8
1.8
—
—
—
0
0
6
120
0.50
0.93
1.0
1.1
—
—
—
0
0
152
1323
1.15
0.93
1.5
1.3
—
—
—
0
0
6
28
2.14
0.91
1.0
1.0
—
—
—
0
0
53
664
0.80
0.91
1.3
1.1
100.0
137.8
titre
—
6
121
133
1151
1.15
0.89
1.6
1.3
109.7
130.0
u/ml
1.39
35
246
738
6953
1.06
0.88
1.5
1.5
—
—
—
0
0
223
1997
1.12
0.88
1.1
1.1
—
—
—
0
0
153
1340
1.14
0.87
2.6
2.4
—
—
—
0
0
27
368
0.73
0.86
1.5
1.5
—
—
—
0
0
50
395
1.26
0.86
1.7
1.7
62.1
1039.3
u/l
1.71
24
159
1287
12325
1.05
0.85
1.3
1.3
—
—
—
0
0
11
64
1.72
0.85
1.5
1.2
—
—
—
0
0
11
64
1.72
0.85
2.1
1.7
16.5
18.0
umol/l
0.22
11
64
21
298
0.70
0.85
1.7
1.8
18.0
174.5
ug/l
0.94
21
273
112
962
1.16
0.84
1.8
1.8
185.6
192.5
pmol/l
0.27
100
892
199
2207
0.90
0.80
3.6
3.8
31.0
29.1
mg/l
0.34
136
1434
897
9385
0.95
0.79
6.0
5.9
1.4
1.4
mmol/l
0.21
863
8999
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
0
26
0.00
0.78
0.0
2.0
—
—
—
0
0
132
1156
1.14
0.78
1.1
1.0
—
—
—
0
0
5
97
0.51
0.78
1.2
1.5
—
—
—
0
0
13
198
0.65
0.77
1.1
1.2
—
—
—
0
0
5
100
0.50
0.77
1.0
1.4
—
—
—
0
0
700
6621
1.06
0.77
1.5
1.5
—
—
—
0
0
110
952
1.15
0.77
3.4
3.0
75.3
37.7
mg/l
0.71
83
690
807
7664
1.05
0.76
1.5
1.5
—
—
—
0
0
262
2391
1.10
0.75
1.6
1.5
0.2
0.2
g/l
0.56
249
2232
94
806
1.17
0.74
2.9
3.0
—
—
—
0
0
82
958
0.85
0.73
1.1
1.1
—
—
—
0
0
9
55
1.63
0.73
2.7
3.6
—
—
—
0
0
145
1626
0.89
0.73
1.4
1.4
—
—
—
0
0
10
60
1.66
0.71
1.1
1.0
—
—
—
0
0
10
60
1.66
0.71
1.0
1.3
2386.4
1303.4
u/l
—
10
54
28
211
1.32
0.70
1.0
1.1
0.7
0.7
umol/24h
0.17
11
96
11
170
0.65
0.70
3.2
2.7
107.1
1891.7
u/l
1.93
11
160
5
26
1.92
0.70
5.0
5.6
599.8
356.6
umol/l
—
5
26
146
1632
0.89
0.70
2.8
2.5
—
—
—
0
0
120
1054
1.14
0.70
1.4
1.3
—
—
—
0
0
699
6634
1.05
0.70
3.4
3.2
124.8
126.5
g/l
1.20
678
6478
70
824
0.85
0.69
1.3
1.3
—
—
—
0
0
631
6634
0.95
0.69
4.3
3.5
—
—
—
0
0
40
318
1.26
0.69
2.5
2.8
30.8
28.4
umol/l
0.42
25
238
49
400
1.22
0.67
1.9
2.0
804.0
1584.1
u/ml
2.01
49
392
59
491
1.20
0.67
2.0
2.0
475.5
511.4
e6/l
0.25
52
408
6737
67897
0.97
0.67
23.5
23.5
331.0
330.8
g/l
0.81
6678
67167
102
1161
0.88
0.66
1.6
1.7
—
—
—
0
0
5
94
0.53
0.66
1.2
1.4
—
—
—
0
0
1301
12546
1.04
0.66
6.1
6.3
5.0
5.1
kpa
1.47
1234
11897
5
95
0.52
0.66
1.2
1.4
—
—
—
0
0
1300
12538
1.04
0.66
6.0
6.3
12.1
11.9
kpa
0.67
1237
11873
28
214
1.31
0.65
1.1
1.3
53.0
83.2
mu/l
0.67
20
148
37
294
1.26
0.65
22.5
26.8
95.8
106.5
ug/l
0.67
32
247
42
340
1.23
0.63
1.2
1.9
40.8
106.4
umol/l
5.68
25
199
29
224
1.29
0.63
1.1
1.1
—
—
—
0
0
29
224
1.29
0.63
1.1
1.1
—
—
—
0
0
29
224
1.29
0.63
1.1
1.1
—
—
—
0
0
139
1546
0.90
0.63
1.4
1.5
1761.2
2345.7
e6/l
0.66
102
1111
266
2455
1.08
0.63
1.6
1.5
1.2
1.2
g/l
0.55
252
2299
125
1398
0.89
0.63
1.4
1.5
99100.9
54189.1
e6/l
0.38
71
835
24
313
0.76
0.62
2.1
1.8
—
—
—
0
0
31
243
1.27
0.61
1.6
1.3
—
—
—
0
0
64
543
1.18
0.61
2.2
2.2
92.9
161.7
ug/min
0.56
25
120
68
581
1.17
0.60
1.5
2.1
4.7
1.9
u/field
0.71
49
386
987
9496
1.04
0.58
7.1
6.3
11.3
11.1
mmol/l
0.21
929
8924
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
26
201
1.29
0.58
1.0
1.3
—
—
—
0
0
66
565
1.17
0.58
2.0
1.8
16.1
15.4
%
0.09
20
213
109
969
1.12
0.56
2.2
2.3
2.3
2.2
u/field
0.05
37
350
36
440
0.82
0.56
2.1
2.7
40.3
36.4
%
0.58
22
153
12
172
0.70
0.56
5.8
4.4
62.1
42.3
u/l
—
7
59
34
274
1.24
0.55
1.5
1.4
15.8
17.5
pmol/l
0.87
27
217
211
1944
1.08
0.55
2.4
2.3
33.2
32.7
umol/l
0.09
162
1591
123
1361
0.90
0.54
1.5
1.6
—
—
—
0
0
44
524
0.84
0.54
1.0
1.0
298.4
293.3
mg/l
0.20
37
466
71
617
1.15
0.53
1.8
2.0
39.0
40.7
%
0.16
13
63
54
630
0.85
0.53
4.4
3.7
—
—
—
0
0
253
2355
1.07
0.52
1.3
1.3
—
—
—
0
0
42
500
0.84
0.52
5.1
4.0
—
—
—
0
0
1310
13445
0.97
0.51
6.2
6.3
104.2
104.3
mmol/l
0.28
1270
13146
52
442
1.17
0.51
1.1
1.1
—
—
—
0
0
118
1062
1.11
0.51
1.2
1.3
—
—
—
0
0
123
1111
1.11
0.50
1.3
1.3
270.1
291.4
pmol/l
0.24
96
830
23
179
1.28
0.50
1.2
1.4
15.1
23.2
%
0.66
14
139
200
1848
1.08
0.50
1.5
1.5
—
—
—
0
0
221
2052
1.08
0.49
1.2
1.2
91.1
164.7
titre
1.30
19
164
108
1195
0.90
0.49
3.7
3.4
—
—
—
0
0
7
107
0.65
0.48
1.1
1.2
—
—
—
0
0
27
216
1.25
0.48
1.5
1.6
98.1
125.5
ng/l
1.17
27
216
38
316
1.20
0.48
2.0
2.2
—
—
—
0
0
40
474
0.84
0.48
1.1
1.1
—
—
—
0
0
25
311
0.80
0.48
1.4
1.8
3569.7
16253.7
e6/l
1.23
14
175
12
166
0.72
0.48
1.0
1.1
—
—
—
0
0
305
2868
1.06
0.48
1.2
1.2
—
—
—
0
0
114
1030
1.11
0.47
2.1
1.7
298.2
316.0
mu/l
0.33
102
947
17
128
1.33
0.47
1.1
1.2
114.7
829.8
ng/l
—
7
83
160
1471
1.09
0.46
2.2
2.2
23.2
26.4
mg/l
0.30
30
387
47
547
0.86
0.46
4.7
3.8
—
—
—
0
0
32
263
1.21
0.46
2.3
1.5
—
—
—
0
0
27
218
1.24
0.45
1.0
1.3
136.9
136.9
nmol/l
0.00
22
149
25
200
1.25
0.45
1.5
1.5
10.4
9.4
%
—
7
110
1282
12464
1.03
0.45
5.0
4.9
33.5
33.5
%
0.01
788
7960
49
566
0.86
0.44
1.0
1.0
0.5
1.0
u/ml
0.89
19
229
30
246
1.22
0.44
2.1
2.2
—
—
—
0
0
86
769
1.12
0.44
1.2
1.3
92.5
64.8
titre
—
8
63
241
2559
0.94
0.43
1.6
1.6
12580.0
16014.0
e6/l
0.88
176
1803
29
350
0.83
0.43
1.4
2.0
1194.9
3382.7
e6/l
0.44
19
238
107
1174
0.91
0.43
1.4
1.5
—
—
—
0
0
29
238
1.22
0.43
1.1
1.2
340.6
267.4
pmol/l
0.39
21
162
18
139
1.29
0.43
1.8
1.4
—
—
—
0
0
17
218
0.78
0.43
6.5
6.2
—
—
—
0
0
22
175
1.25
0.42
5.4
2.5
—
—
—
0
0
76
677
1.12
0.42
1.4
1.3
—
—
—
0
0
17
217
0.78
0.41
19.7
15.1
1491.8
1388.5
nmol/l
0.29
17
208
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.6
—
118.6
—
0
10
47
539
0.87
0.40
5.2
6.0
—
—
—
0
0
2280
22372
1.02
0.40
4.5
4.1
—
—
—
0
0
12
160
0.75
0.40
1.1
1.2
—
1448.0
—
0
10
38
324
1.17
0.39
1.2
1.3
—
—
—
0
0
1035
10595
0.97
0.38
3.8
3.6
7.4
7.4
ph
—
8
49
49
428
1.14
0.38
1.1
1.0
—
—
—
0
0
9
68
1.32
0.37
1.2
1.1
—
—
—
0
0
16
202
0.79
0.37
1.5
1.5
—
—
—
0
0
46
524
0.88
0.37
1.8
1.6
—
—
—
0
0
88
799
1.10
0.36
1.2
1.3
256.7
423.4
titre
—
9
82
92
1005
0.91
0.36
1.6
1.4
—
—
—
0
0
92
1005
0.91
0.36
1.6
1.4
—
—
—
0
0
92
1005
0.91
0.36
1.6
1.4
—
—
—
0
0
92
1005
0.91
0.36
1.6
1.4
—
—
—
0
0
164
1530
1.07
0.36
1.4
1.3
—
—
—
0
0
36
308
1.17
0.36
1.2
1.4
18.4
23.1
%
0.48
29
257
39
336
1.16
0.36
2.2
2.1
55.9
57.5
umol/l
0.11
27
254
52
458
1.13
0.36
1.1
1.1
—
—
—
0
0
136
1261
1.08
0.36
1.2
1.2
—
—
—
0
0
6
42
1.43
0.35
1.2
1.4
349.0
324.6
umol/24h
—
6
42
206
2177
0.94
0.35
1.5
1.5
—
—
—
0
0
89
971
0.91
0.35
1.2
1.2
2.8
4.4
u/ml
2.25
33
422
99
907
1.09
0.35
1.2
1.2
—
—
—
0
0
16
126
1.27
0.34
7.6
12.8
6.9
5.1
mmol/l
0.74
16
126
29
340
0.85
0.34
1.4
1.4
70.7
57.8
%
1.49
23
287
1000
10221
0.97
0.34
3.9
3.6
1.9
2.0
mmol/l
0.21
788
8338
866
8869
0.97
0.34
1.4
1.4
—
—
—
0
0
100
918
1.09
0.34
1.2
1.3
15.4
12.6
u/l
0.29
94
830
48
540
0.89
0.33
1.1
1.1
—
—
—
0
0
127
1360
0.93
0.33
1.4
1.5
—
—
—
0
0
54
602
0.89
0.32
1.2
1.2
—
—
—
0
0
105
1132
0.92
0.32
3.2
3.3
62.1
58.5
%
0.80
59
719
38
331
1.15
0.32
1.2
1.5
—
—
—
0
0
10
74
1.35
0.32
1.0
1.1
—
22.6
—
0
24
2302
23290
0.98
0.31
6.0
6.7
—
—
—
0
0
19
155
1.22
0.31
1.7
1.7
—
—
—
0
0
2110
20749
1.02
0.31
4.1
4.1
431.2
408.0
ng/l
0.07
1804
17836
248
2596
0.95
0.31
4.0
3.6
7.9
7.7
mmol/l
0.46
241
2543
23
192
1.20
0.31
1.1
1.0
—
—
—
0
0
242
2302
1.05
0.30
2.9
3.1
889.7
636.1
u/ml
0.19
228
2087
290
2773
1.04
0.30
1.4
1.4
—
—
—
0
0
26
221
1.17
0.30
1.1
1.2
1.9
1.5
mmol/l
0.71
15
132
65
712
0.91
0.29
3.9
5.0
84.3
101.1
u/ml
0.13
18
213
36
315
1.14
0.29
1.0
1.0
0.2
0.2
u/ml
—
9
99
269
2571
1.05
0.29
1.2
1.2
—
—
—
0
0
8
108
0.74
0.29
1.9
1.3
—
—
—
0
0
113
1053
1.07
0.28
1.5
1.3
12.4
12.7
u/l
0.08
94
836
45
401
1.12
0.28
2.0
1.8
—
—
—
0
0
191
1811
1.05
0.28
3.3
3.4
1.5
1.4
%
0.12
141
1373
61
668
0.91
0.28
1.1
1.1
0.4
1.4
u/ml
2.03
24
254
535
5495
0.97
0.28
1.5
1.6
1.6
1.6
g/l
0.01
430
4659
20
237
0.84
0.28
1.6
1.4
—
—
—
0
0
23
195
1.18
0.27
1.0
1.1
0.6
1.1
u/ml
—
6
70
24
278
0.86
0.26
1.3
1.9
—
—
—
0
0
44
394
1.11
0.26
1.0
1.0
1.5
2.7
u/ml
0.82
20
163
15
123
1.22
0.25
1.1
1.1
1.2
0.6
u/ml
—
6
53
6
81
0.74
0.24
1.0
1.1
—
—
—
0
0
1177
11940
0.98
0.24
3.6
3.8
12.8
22.9
ug/l
1.80
981
9854
119
1121
1.06
0.24
1.4
1.4
6.6
6.4
mmol/l
0.20
114
1024
369
3797
0.97
0.23
2.5
2.2
507.3
589.1
ug/l
0.24
347
3568
11
136
0.81
0.23
1.4
1.7
75.7
63.5
pmol/l
—
6
109
21
180
1.16
0.23
16.6
8.2
—
—
—
0
0
21
180
1.16
0.23
1.2
1.3
—
—
—
0
0
440
4511
0.97
0.22
3.4
4.1
86.9
77.4
u/ml
0.11
419
4327
350
3601
0.97
0.22
2.8
2.9
0.4
0.3
g/l
1.13
141
1375
5
41
1.22
0.22
2.0
1.6
0.4
1.9
%
—
5
41
211
2024
1.04
0.22
1.2
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
41
373
1.10
0.20
1.3
1.4
19.8
12.8
umol/l
0.26
23
262
17
145
1.17
0.20
5.8
7.7
—
—
—
0
0
42
383
1.09
0.20
1.0
1.1
8.8
12.2
iu/ml
—
7
90
11
133
0.83
0.19
1.0
1.1
—
—
—
0
0
436
4247
1.03
0.19
1.3
1.3
—
—
—
0
0
126
1199
1.05
0.19
1.3
1.4
45.4
59.6
mu/l
0.70
109
1048
41
374
1.09
0.19
1.0
1.0
1.9
1.8
u/ml
0.02
19
155
54
579
0.93
0.18
1.0
1.0
1.6
2.6
u/ml
0.76
28
255
13
109
1.19
0.18
1.1
1.2
—
—
—
0
0
1010
10223
0.98
0.18
3.8
3.6
5.8
5.8
kpa
0.18
975
9917
17
195
0.87
0.18
1.2
1.6
—
—
—
0
0
7
59
1.18
0.18
1.0
1.1
—
—
—
0
0
101
1059
0.95
0.17
1.7
1.7
—
—
—
0
0
7
62
1.13
0.17
6.0
5.3
—
—
—
0
0
11
91
1.21
0.17
1.1
1.1
—
—
—
0
0
265
2720
0.97
0.17
3.8
3.5
1.6
1.7
mmol/l
0.18
257
2661
5
66
0.76
0.17
1.0
1.0
—
—
—
0
0
5
66
0.76
0.17
1.0
1.0
—
—
—
0
0
12
101
1.19
0.16
2.2
3.7
7.5
7.8
mmol/l
—
5
64
22
196
1.12
0.16
1.5
1.8
1.2
1.2
mmol/l
0.06
22
188
105
1002
1.05
0.15
1.4
1.4
120170.4
173404.4
e6/l
0.29
69
681
44
472
0.93
0.15
2.1
1.5
6.5
6.5
u/l
0.00
39
379
317
3088
1.03
0.15
1.8
1.8
22.3
21.9
s
0.29
267
2777
6
76
0.79
0.15
1.0
1.0
—
—
—
0
0
144
1385
1.04
0.15
6.2
6.3
13.6
12.4
mg/l
2.11
124
1238
709
6968
1.02
0.15
1.6
1.6
—
—
—
0
0
36
331
1.09
0.15
1.3
1.4
57.6
146.0
pmol/l
0.51
17
109
106
1015
1.04
0.14
1.1
1.1
77.3
425.4
iu/ml
0.74
24
199
112
1074
1.04
0.14
1.3
1.3
39.7
37.7
iu/l
0.23
96
910
102
1060
0.96
0.14
1.1
1.1
—
—
—
0
0
120
1154
1.04
0.13
1.4
1.3
—
—
—
0
0
8
99
0.81
0.13
2.0
1.5
—
—
—
0
0
301
3070
0.98
0.13
3.2
3.2
0.8
0.8
nmol/l
0.52
242
2389
28
256
1.09
0.13
1.4
1.3
30.9
33.7
%
0.14
18
170
10
84
1.19
0.13
1.0
1.2
—
—
—
0
0
10
84
1.19
0.13
1.0
1.2
—
—
—
0
0
10
84
1.19
0.13
1.0
1.2
—
—
—
0
0
167
1715
0.97
0.12
1.7
1.7
—
—
—
0
0
112
1158
0.96
0.12
1.2
1.1
—
—
—
0
0
575
5657
1.02
0.12
7.8
8.7
—
—
—
0
0
21
190
1.10
0.12
1.0
1.1
—
—
—
0
0
422
4279
0.98
0.11
2.3
2.2
10.4
10.2
g/l
0.36
326
3495
289
2941
0.98
0.11
11.6
11.9
—
—
—
0
0
51
536
0.95
0.11
1.1
1.2
11.7
12.1
mmol/l
0.15
19
160
164
1595
1.03
0.11
2.3
1.4
0.7
0.8
nmol/l
2.87
135
1316
42
396
1.06
0.10
1.7
1.5
0.1
0.2
nmol/l
0.65
28
274
13
115
1.13
0.10
1.8
1.5
40.5
46.7
umol/l
0.42
13
115
49
465
1.05
0.10
1.0
1.0
0.8
1.7
u/ml
0.63
15
115
50
475
1.05
0.10
1.6
1.3
1.2
1.2
nmol/l
0.17
37
360
55
524
1.05
0.10
1.5
1.6
—
—
—
0
0
11
96
1.14
0.10
1.0
1.2
1.7
1.7
umol/24h
0.05
11
96
5
45
1.11
0.09
1.2
1.4
—
—
—
0
0
27
251
1.07
0.09
1.3
1.5
14.5
14.5
g/l
0.01
19
199
5
46
1.08
0.09
1.2
1.4
—
—
—
0
0
111
1077
1.03
0.09
1.3
1.2
296.0
292.8
u/ml
0.05
74
650
675
6802
0.99
0.09
1.5
1.4
—
—
—
0
0
13
144
0.90
0.08
2.4
2.9
0.2
0.5
u/field
1.34
13
144
18
165
1.09
0.08
1.2
1.2
3.9
1.3
mmol/l
0.50
12
102
141
1439
0.98
0.08
1.5
1.8
20.1
22.4
ug/l
0.31
136
1394
5
62
0.80
0.08
1.0
1.2
—
—
—
0
0
430
4241
1.01
0.08
2.1
2.0
—
—
—
0
0
944
9351
1.01
0.08
1.8
2.1
0.2
0.2
g/l
0.12
858
8611
170
1664
1.02
0.07
1.3
1.3
27.6
42.4
u/l
2.05
138
1436
95
923
1.03
0.07
1.1
1.1
—
13.5
—
0
30
7
81
0.86
0.07
1.1
1.1
—
—
—
0
0
7
84
0.83
0.07
2.3
2.5
591.7
439.2
umol/l
—
7
77
39
372
1.05
0.07
1.3
1.3
737.4
306.2
ug/l
0.38
21
204
51
528
0.96
0.07
2.0
2.2
630.7
586.4
e6/l
0.24
34
217
411
4144
0.99
0.07
3.9
4.1
24.8
25.0
mmol/l
0.77
363
3742
9
87
1.03
0.07
1.7
1.9
—
—
—
0
0
17
183
0.93
0.07
1.3
1.6
1.7
2.5
ug/l
—
9
98
46
477
0.96
0.06
1.1
1.2
332.1
333.3
u/l
0.00
39
444
297
2928
1.01
0.06
1.6
1.6
—
—
—
0
0
74
718
1.03
0.06
1.1
1.0
—
—
—
0
0
53
511
1.04
0.06
1.4
1.4
11.7
14.4
umol/l
2.51
48
477
188
1905
0.98
0.06
1.6
1.5
—
—
—
0
0
105
1025
1.02
0.06
1.3
1.5
—
—
—
0
0
178
1804
0.98
0.06
1.5
1.5
241.3
221.1
pmol/l
0.17
168
1752
666
6692
0.99
0.06
7.9
7.8
93.9
93.7
%
0.39
660
6668
843
8460
0.99
0.05
3.3
3.0
4.5
4.4
kpa
0.36
810
8169
100
978
1.02
0.05
1.2
1.2
—
—
—
0
0
152
1494
1.02
0.05
1.3
1.2
—
—
—
0
0
12
130
0.92
0.05
1.2
1.2
8.3
6.4
mmol/l
—
6
56
1594
15955
1.00
0.04
29.9
29.9
1.4
1.5
inr
0.99
236
2120
39
401
0.97
0.03
2.0
2.5
—
—
—
0
0
61
621
0.98
0.03
1.5
1.6
—
—
—
0
0
20
209
0.95
0.03
1.5
1.6
73.1
115.5
ug/l
1.92
15
175
76
771
0.98
0.03
1.1
1.1
32.8
34.5
mmol/l
0.27
65
630
65
637
1.02
0.03
2.0
1.5
1681.1
1835.9
ml
0.34
20
183
15
158
0.95
0.02
1.3
1.2
—
—
—
0
0
39
398
0.98
0.02
11.2
3.2
8868.5
66.3
mg/l
0.48
21
268
484
4846
1.00
0.02
3.7
3.8
—
—
—
0
0
67
659
1.01
0.02
2.5
2.5
—
—
—
0
0
76
749
1.01
0.02
1.9
2.0
2.7
2.3
ug/l
0.31
62
631
78
770
1.01
0.01
1.8
1.9
5.4
3.9
ug/l
0.46
67
676
65
656
0.99
0.01
1.6
2.2
7.1
7.1
mmol/l
0.03
37
440
55
542
1.01
0.01
1.1
1.1
—
—
—
0
0
509
5071
1.00
0.00
2.8
2.5
0.7
0.7
%
0.31
486
4877
10
94
1.06
0.00
1.0
1.1
—
—
—
0
0
14
136
1.03
0.00
1.7
2.5
—
—
—
0
0
14
144
0.97
0.00
2.1
1.8
75.0
1556.8
e6/l
—
6
68
10
103
0.97
0.00
12.7
13.0
—
—
—
0
0
32
317
1.01
0.00
1.9
2.4
—
33.2
—
0
9
101
1008
1.00
0.00
1.1
1.1
1.5
1.6
g/l
0.35
87
900
55
545
1.01
0.00
1.1
1.1
—
—
—
0
0
36
362
0.99
0.00
2.4
2.4
—
—
—
0
0
22
218
1.01
0.00
16.3
8.0
—
—
—
0
0
82
823
0.99
0.00
1.1
1.1
—
—
—
0
0
97
964
1.00
0.00
1.3
1.2
194.3
212.0
miu/ml
0.18
31
317
174
1740
1.00
0.00
1.4
1.5
30.8
31.6
g/l
0.34
158
1541
457
4559
1.00
0.00
2.3
2.2
3.9
3.8
g/l
0.50
292
3158
120
1199
1.00
0.00
3.4
3.9
—
—
—
0
0
38
376
1.01
0.00
1.2
1.2
40.7
39.6
g/l
0.16
20
188
215
2147
1.00
0.00
3.1
2.6
—
—
—
0
0
30
302
0.99
0.00
1.2
1.1
—
—
—
0
0
71
703
1.01
0.00
1.5
1.4
—
—
—
0
0
14
139
1.01
0.00
1.1
1.2
—
—
—
0
0
74
735
1.00
0.00
1.1
1.1
1.5
3.9
u/ml
2.48
23
213
19
192
0.99
0.00
1.5
1.5
—
—
—
0
0
5
55
0.91
0.00
1.0
1.1
—
—
—
0
0
6
61
0.98
0.00
1.2
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
6.0
—
6.7
—
0
6
8
85
0.94
0.00
1.1
1.1
10.2
8.3
mg/g
—
8
79
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
43.7
—
0
7
0
6
0.00
0.00
0.0
1.0
—
31.0
—
0
6
6
69
0.87
0.00
1.2
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
11.7
—
0
7
8
83
0.96
0.00
1.0
1.1
—
—
—
0
0
8
87
0.92
0.00
4.6
6.8
0.4
0.6
umol/l
—
8
79
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_GLAUCOMA_POAG and mortality.

Females

Parameter HR [95% CI] p-value
H7_GLAUCOMA_POAG 0.931 [0.86, 1.0] 0.066
Birth year 0.995 [0.99, 1.0] 0.189

During the follow-up period (1.1.1998 — 31.12.2019), 12269 out of 40833 females with H7_GLAUCOMA_POAG died.

Males

Parameter HR [95% CI] p-value
H7_GLAUCOMA_POAG 0.979 [0.9, 1.07] 0.634
Birth year 0.99 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 8092 out of 26243 males with H7_GLAUCOMA_POAG died.

Mortality risk

Mortality risk for people of age

years, who have H7_GLAUCOMA_POAG.

N-year risk Females Males
1 0.078% 0.177%
5 0.52% 1.151%
10 1.36% 3.123%
15 2.46% 6.173%
20 4.383% 10.442%

Relationships between endpoints

Index endpoint: H7_GLAUCOMA_POAG – Primary open-angle glaucoma, strict

GWS hits: 71

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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