retroperitoneal cancer: An organ system cancer located_in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.
Benign neoplasm of soft tissue of retroperitoneum and peritoneum
DOID EFO Endpoint Browser PheWeb
CD2_BENIGN_RETROPERITONEUM_PERITONEUM
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
182 |
4. Check minimum number of eventsNone |
182 |
5. Include endpointsNone |
182 |
6. Filter based on genotype QC (FinnGen only) |
182 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 2
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D10-D36
- Name in latin
- Neoplasma benignum telae mollis spatii retroperitonealis et/sive peritonei
Similar endpoints
↥List of similar endpoints to
Benign neoplasm of soft tissue of retroperitoneum and peritoneum
based on the number of shared cases.
Similar with more cases:
- Benign neoplasm of soft tissue of retroperitoneum and peritoneum
- Benign neoplasms
- Benign neoplasms
- Neoplasms
- Any operation in hilmo
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1295 | 851 | 432 |
| Only index persons | 1064 | 738 | 326 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.02 | 0.02 | 0.01 |
| Only index persons | 0.02 | 0.03 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 56.26 | 53.03 | 62.62 |
| Only index persons | 53.21 | 50.40 | 59.57 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 182 | 132 | 50 |
| Unadjusted period prevalence (%) | 0.04 | 0.04 | 0.02 |
| Median age at first event (years) | 55.96 | 52.16 | 66.01 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 176
- Matched controls
- 1761
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D20.0
ICD-10 Finland
Benign neoplasm: Retroperitoneum
+∞
126.9
106
*
D20.1
ICD-10 Finland
Benign neoplasm: Peritoneum
+∞
56.3
51
*
D48.3
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Retroperitoneum
187.0
16.8
17
*
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
9.0
11.0
23
29
21170
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Peritoneum and retroperitoneal tissue
+∞
10.5
10
*
KKB10
NOMESCO Finland
Excision of retroperitoneal tumour
+∞
10.5
10
*
JAH00
NOMESCO Finland
Laparotomy
11.0
9.8
18
18
JAH01
NOMESCO Finland
Laparoscopy
6.1
9.0
24
44
D20
ICD-10 Finland
Benign neoplasm of soft tissue of retroperitoneum and peritoneum
+∞
8.4
8
*
UJF32
NOMESCO Finland
Coloscopy
2.8
8.0
63
294
UKC02
NOMESCO Finland
Cystoscopy
3.5
7.9
39
134
WX302
NOMESCO Finland
Thoracal epidural anesthesy
5.7
7.5
21
41
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
12.8
7.2
12
10
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
10.7
7.2
13
13
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
7.1
34
114
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
6.5
86
518
2118X
ICD-9 Finland
Benign neoplasm of other parts of digestive system, Retroperitoneum and peritoneum[NEOPLASMA BENIGNUM ALIUD SPATII RETROPERITON ET PER]
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
105
3.62
9.04
3.8
2.4
49.0
41.7
u/ml
0.15
33
100
44
176
2.98
8.29
3.0
4.2
5.7
8.9
ug/l
0.47
33
141
67
338
2.55
8.03
3.1
2.1
—
—
—
0
0
100
686
2.02
5.10
4.6
3.9
—
—
—
0
0
68
446
1.84
3.66
3.5
3.1
1361.7
1329.7
ng/l
0.03
60
376
112
856
1.80
3.59
10.8
9.9
4.4
4.0
e9/l
0.69
92
751
59
376
1.84
3.45
3.3
2.7
327.5
7311.3
umol/l
2.28
52
311
40
227
1.98
3.30
2.9
2.7
3.3
3.1
e6/l
0.06
26
125
134
1096
1.84
3.27
5.3
3.9
15.0
12.5
mm/h
0.90
124
988
106
814
1.72
3.19
9.0
5.7
11.5
10.7
umol/l
0.44
97
765
53
339
1.79
3.02
1.7
1.7
1.0
1.1
mg/l
0.06
40
278
7
13
5.55
2.89
3.6
2.5
6.6
4.0
nmol/l
—
7
13
6
9
6.85
2.89
3.3
1.9
—
—
—
0
0
138
1158
1.79
2.87
11.4
7.0
87.8
78.0
u/l
0.86
129
1069
73
521
1.67
2.78
3.7
2.9
—
—
—
0
0
55
366
1.72
2.71
2.6
2.1
2.7
3.2
mg/l
0.91
48
309
39
235
1.84
2.68
2.7
2.5
0.7
0.9
e6/l
0.32
24
131
88
668
1.61
2.58
8.6
5.3
1.2
1.2
mmol/l
0.58
80
601
18
82
2.33
2.57
1.5
1.3
—
—
—
0
0
10
34
3.05
2.45
1.5
1.8
—
—
—
0
0
32
186
1.87
2.45
3.9
4.7
33.4
33.5
%
0.02
25
114
76
578
1.54
2.11
4.4
3.6
55.6
42.1
ng/l
0.23
53
394
23
129
1.90
1.97
3.3
2.2
0.2
0.2
g/l
0.12
23
120
17
86
2.08
1.92
3.4
3.0
5.2
5.2
kpa
0.12
17
78
91
731
1.49
1.90
8.9
5.7
1.2
1.2
mmol/l
0.44
80
608
114
959
1.51
1.89
4.7
3.0
62.0
44.4
u/l
0.75
107
898
19
101
1.98
1.89
1.4
1.5
—
—
—
0
0
5
12
4.25
1.83
3.2
1.5
—
—
—
0
0
40
270
1.62
1.82
1.2
1.3
13.0
31.2
iu/ml
1.76
11
88
6
18
3.41
1.76
1.2
1.2
—
—
—
0
0
8
30
2.74
1.74
1.6
1.4
—
—
—
0
0
5
13
3.92
1.72
3.2
1.5
—
—
—
0
0
26
161
1.72
1.64
6.3
7.0
0.4
1.6
mmol/l
0.81
20
135
12
58
2.14
1.53
1.5
2.7
1.3
0.8
g/l
0.19
12
50
7
29
2.47
1.40
1.9
1.4
—
—
—
0
0
45
331
1.48
1.40
2.0
1.8
257500425.9
477.5
pmol/l
0.49
40
273
13
68
1.98
1.37
1.5
2.3
—
—
—
0
0
128
1137
1.42
1.36
5.1
4.1
14.9
14.7
pmol/l
0.46
117
1024
158
1468
1.58
1.27
22.5
13.8
25.4
22.9
mg/l
0.44
140
1164
43
320
1.45
1.26
1.3
1.3
0.6
1.8
u/ml
1.10
12
84
8
36
2.28
1.26
1.1
1.1
—
—
—
0
0
9
45
2.05
1.25
1.0
1.3
—
—
—
0
0
8
38
2.15
1.20
1.5
1.2
—
—
—
0
0
35
253
1.47
1.18
1.2
1.3
3.7
10.2
u/ml
1.11
19
92
73
602
1.36
1.17
2.3
2.0
105.3
98.7
pmol/l
0.36
38
286
52
406
1.39
1.17
4.1
2.9
0.7
0.5
e6/l
0.18
38
301
0
35
0.00
1.16
0.0
2.7
—
61.2
—
0
23
5
20
2.54
1.16
1.8
1.2
—
—
—
0
0
8
40
2.05
1.13
1.8
1.4
—
—
—
0
0
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
5
21
2.42
1.10
1.8
1.2
—
—
—
0
0
11
60
1.89
1.05
2.9
2.4
0.5
0.7
%
1.49
11
60
86
739
1.31
1.01
4.0
3.9
0.0
0.0
estimate
0.00
13
130
27
192
1.48
1.00
8.6
6.7
—
—
—
0
0
10
54
1.90
0.98
2.2
1.5
—
—
—
0
0
10
54
1.90
0.98
1.6
2.6
39.5
37.8
g/l
—
10
47
5
23
2.21
0.98
5.0
3.2
49.7
57.9
u/ml
—
5
23
147
1367
1.39
0.96
6.1
4.9
2.1
1.9
mu/l
0.32
137
1237
11
62
1.82
0.96
1.5
2.4
10.0
10.0
g/l
0.00
11
54
47
374
1.35
0.93
1.9
1.6
19.8
21.9
nmol/l
0.43
42
303
13
204
0.61
0.92
3.3
4.4
20.9
21.6
%
—
5
99
11
63
1.79
0.92
2.9
2.4
0.9
1.1
%
0.53
11
63
7
129
0.52
0.92
1.3
1.7
—
—
—
0
0
14
87
1.66
0.90
1.7
1.7
—
—
—
0
0
8
42
1.95
0.90
1.8
1.4
—
—
—
0
0
37
287
1.36
0.86
2.3
3.0
2.5
2.5
mmol/l
0.03
32
249
84
732
1.27
0.85
5.5
5.2
0.0
0.0
estimate
0.00
13
138
18
124
1.50
0.78
2.7
2.9
72.3
67.5
ml/min/173m2
—
6
50
10
60
1.71
0.73
1.7
1.9
—
—
—
0
0
10
60
1.71
0.73
1.3
1.6
—
—
—
0
0
5
25
2.03
0.73
2.6
2.7
—
20.1
—
0
7
72
628
1.24
0.70
3.3
2.2
80.9
78.5
nmol/l
0.30
64
545
37
299
1.30
0.67
4.2
3.7
333.1
186.0
ng/l
0.26
32
232
148
1403
1.29
0.65
19.4
13.2
76.8
79.5
ml/min/173m2
0.70
127
1139
30
238
1.31
0.62
2.1
1.8
—
—
—
0
0
27
211
1.33
0.61
3.5
1.8
27.3
29.3
s
2.03
27
205
22
168
1.35
0.58
9.7
4.1
248.3
248.3
u/l
0.00
22
156
7
48
1.48
0.47
2.3
4.9
25.5
24.3
mg/l
—
7
35
7
48
1.48
0.47
2.3
4.8
151.2
219.1
mg/l
—
7
35
7
50
1.42
0.45
1.4
1.4
—
—
—
0
0
137
1306
1.20
0.45
21.5
15.3
38.6
39.6
%
0.89
94
943
5
31
1.63
0.43
1.4
1.5
—
—
—
0
0
8
56
1.45
0.43
1.5
1.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
20
160
1.28
0.40
2.1
1.7
—
—
—
0
0
21
257
0.79
0.40
1.7
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
34
295
1.19
0.35
2.2
1.7
1219.4
1229.2
nmol/l
0.02
24
220
79
733
1.14
0.34
4.0
3.8
0.0
0.0
estimate
0.00
12
142
95
896
1.13
0.31
3.4
3.0
—
—
—
0
0
25
289
0.84
0.29
1.3
1.4
—
—
—
0
0
141
1365
1.15
0.29
6.1
5.6
40.1
39.7
mmol/mol
0.22
130
1272
19
159
1.22
0.28
3.9
3.6
—
—
—
0
0
8
67
1.20
0.26
2.3
2.1
38.0
41.5
u/l
—
8
58
11
137
0.79
0.25
1.5
2.0
—
—
—
0
0
141
1371
1.13
0.24
4.3
4.0
1.3
1.3
mmol/l
0.01
131
1251
5
37
1.36
0.23
1.0
1.1
—
—
—
0
0
147
1434
1.13
0.22
4.8
4.5
4.7
4.7
mmol/l
0.09
138
1318
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
2.8
—
0
5
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
6
48
1.26
0.20
1.0
1.8
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
32.2
—
0
9
0
14
0.00
0.20
0.0
1.0
—
515.9
—
0
9
7
58
1.22
0.18
2.4
1.8
—
—
—
0
0
146
1429
1.11
0.18
5.1
4.6
5.8
5.9
mmol/l
0.24
137
1308
10
120
0.82
0.17
4.3
4.2
1.2
1.2
mmol/l
—
10
106
7
86
0.81
0.15
1.1
1.0
—
—
—
0
0
7
87
0.80
0.15
1.1
1.4
—
—
—
0
0
42
399
1.07
0.10
1.5
1.7
1.6
1.3
mmol/l
0.62
35
333
6
55
1.09
0.09
1.2
1.2
—
—
—
0
0
6
55
1.09
0.09
1.2
1.2
—
—
—
0
0
18
166
1.09
0.08
2.2
1.8
—
—
—
0
0
144
1428
1.04
0.04
4.7
4.5
1.5
1.5
mmol/l
0.13
134
1305
11
118
0.93
0.03
1.7
1.7
—
—
—
0
0
56
568
0.98
0.01
4.5
4.0
—
—
—
0
0
146
1464
0.99
0.00
5.4
5.0
2.7
2.8
mmol/l
0.38
136
1337
41
407
1.01
0.00
4.1
4.0
0.0
0.0
estimate
0.00
13
135
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
5
58
0.86
0.00
1.4
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
7.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
1937.8
—
0
5
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
4.5
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint CD2_BENIGN_RETROPERITONEUM_PERITONEUM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_RETROPERITONEUM_PERITONEUM | 2.385 [1.89, 3.01] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.1 |
During the follow-up period (1.1.1998 — 31.12.2019), 150 out of 605 females with CD2_BENIGN_RETROPERITONEUM_PERITONEUM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| CD2_BENIGN_RETROPERITONEUM_PERITONEUM | 1.881 [1.45, 2.44] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 336 males with CD2_BENIGN_RETROPERITONEUM_PERITONEUM died.
Mortality risk
Mortality risk for people of age
years, who have CD2_BENIGN_RETROPERITONEUM_PERITONEUM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.204% | 0.449% |
| 5 | 1.191% | 2.385% |
| 10 | 3.436% | 5.42% |
| 15 | 6.315% | 9.864% |
| 20 | 10.745% | 16.087% |
Relationships between endpoints
↥Index endpoint: CD2_BENIGN_RETROPERITONEUM_PERITONEUM – Benign neoplasm of soft tissue of retroperitoneum and peritoneum
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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