Benign neoplasm of soft tissue of retroperitoneum and peritoneum

CD2_BENIGN_RETROPERITONEUM_PERITONEUM

retroperitoneal cancer: An organ system cancer located_in the retroperitoneal space that is manifested in retroperitoneal space in the abdominal cavity behind the peritoneum.

Suggest a new description

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D20 Hospital discharge: ICD-9 — 2118 Hospital discharge: ICD-8 — 2117 Cause of death: ICD-10 — D20 Cause of death: ICD-9 — 2118 Cause of death: ICD-8 — 2117 2 out of 7 registries used, show all original rules.	186
4. Check minimum number of events None	186
5. Include endpoints None	186
6. Filter based on genotype QC (FinnGen only)	183

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 2
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D10-D36
Name in latin: Neoplasma benignum telae mollis spatii retroperitonealis et/sive peritonei

NAME	CD2_BENIGN_RETROPERITONEUM_PERITONEUM
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D20
HD_ICD_9	2118
HD_ICD_8	2117
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D20
COD_ICD_9	2118
COD_ICD_8	2117
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Benign neoplasm of soft tissue of retroperitoneum and peritoneum based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1295	851	432
Only index persons	1064	738	326
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.01
Only index persons	0.02	0.03	0.01
Median age at first event (years)
Whole population	56.26	53.03	62.62
Only index persons	53.21	50.40	59.57

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	183	133	50
Unadjusted period prevalence (%)	0.04	0.05	0.02
Median age at first event (years)	56.41	52.80	66.01

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
186: Matched controls
1860

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D20.0

ICD-10 Finland

Benign neoplasm: Retroperitoneum

+∞

132.7

111

D20.1

ICD-10 Finland

Benign neoplasm: Peritoneum

+∞

58.5

D48.3

ICD-10 Finland

Neoplasm of uncertain or unknown behaviour: Retroperitoneum

222.7

20.0

R19.0

ICD-10 Finland

Intra-abdominal and pelvic swelling, mass and lump

17.3

14.8

JAH01

NOMESCO Finland

Laparoscopy

6.6

14.4

JN3BD

NOMESCO Finland

Extensive abdominal CT

4.1

11.7

107

WX302

NOMESCO Finland

Thoracal epidural anesthesy

6.0

11.7

21170

ICD-8 Finland

Benign neoplasm of other parts of digestive system, Peritoneum and retroperitoneal tissue

+∞

11.6

KKB10

NOMESCO Finland

Excision of retroperitoneal tumour

127.6

11.6

D20

ICD-10 Finland

Benign neoplasm of soft tissue of retroperitoneum and peritoneum

+∞

9.5

JAH00

NOMESCO Finland

Laparotomy

7.7

9.3

UKC02

NOMESCO Finland

Cystoscopy

3.0

7.9

155

UJF32

NOMESCO Finland

Coloscopy

2.5

7.3

327

2118X

ICD-9 Finland

Benign neoplasm of other parts of digestive system, Retroperitoneum and peritoneum[NEOPLASMA BENIGNUM ALIUD SPATII RETROPERITON ET PER]

+∞

7.3

N13.3

ICD-10 Finland

Other and unspecified hydronephrosis

7.9

6.5

XW4AT

NOMESCO Finland

Biopsy of other inner organ with ultrasound guidance

72.2

6.5

JN5DR

NOMESCO Finland

PET-CT of upper body metabolism

18.8

6.3

KBV02

NOMESCO Finland

Cystoscopic insertion of stent into ureter

9.1

6.2

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

2.2

6.1

480

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

105

3.74

9.74

3.7

2.4

48.49

41.73

u/ml

0.14

100

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

347

2.63

8.79

3.1

2.1

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

177

2.95

8.18

3.0

4.2

5.73

8.82

ug/l

0.47

142

(3044640) Blood type and Crossmatch panel - Blood

477

2.29

6.92

3.3

2.1

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

103

699

2.06

5.50

3.4

2.4

—

(3033658) Prothrombin time (PT) actual/Normal

385

1.92

3.99

3.6

3.3

93.92

91.65

0.28

375

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

5.22

3.74

1.1

1.5

3.15

10.46

u/ml

—

(3022217) INR in Platelet poor plasma by Coagulation assay

718

1.77

3.60

14.0

13.0

1.16

1.23

inr

0.30

217

(3026493) Urate [Moles/volume] in Serum or Plasma

388

1.85

3.59

3.3

2.6

328.00

6988.59

umol/l

2.28

326

(40761535) Cells panel - Urine sediment

121

2.34

3.52

2.1

3.0

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

230

2.00

3.50

3.0

2.7

3.34

3.11

e6/l

0.05

126

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

109

829

1.76

3.47

8.9

5.7

11.39

10.67

umol/l

0.40

100

780

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

453

1.79

3.42

3.5

3.1

1361.67

1318.39

ng/l

0.04

380

(3013650) Neutrophils [#/volume] in Blood by Automated count

113

872

1.75

3.39

10.8

9.9

4.42

4.02

e9/l

0.68

763

(3002256) Pathology report gross observation

196

2.04

3.32

1.3

—

(3020779) Urea [Moles/volume] in Serum or Plasma

105

2.36

3.25

7.8

4.5

9.54

9.61

mmol/l

0.01

(3013707) Erythrocyte sedimentation rate by Westergren method

137

1130

1.81

3.13

5.2

3.9

14.87

12.45

mm/h

0.91

127

1019

(40768804) Tissue Pathology biopsy report

656

1.68

3.05

2.4

2.1

—

(3004588) Protein electrophoresis panel - Serum or Plasma

102

2.31

3.01

2.5

2.4

—

(3019198) Lymphocytes [#/volume] in Blood

100

763

1.67

2.98

7.1

5.1

1.97

1.96

e9/l

0.04

681

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

349

1.77

2.95

1.6

1.7

1.04

1.07

mg/l

0.05

286

(3022313) Gas panel - Capillary blood

2.73

2.95

3.3

3.0

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

375

1.75

2.93

2.6

2.1

2.65

3.15

mg/l

1.05

317

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

141

1184

1.79

2.90

11.3

6.9

87.69

77.82

u/l

0.90

132

1095

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

5.55

2.89

3.6

2.5

6.64

3.99

nmol/l

—

(3023601) Vancomycin resistant enterococcus [Presence] in Specimen by Organism specific culture

6.84

2.89

3.3

1.9

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

191

1.95

2.87

3.9

4.6

32.52

33.47

0.19

121

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

239

1.86

2.81

2.9

2.5

0.73

0.92

e6/l

0.29

133

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

682

1.62

2.66

8.5

5.2

1.21

1.22

mmol/l

0.60

619

(3001604) Monocytes [#/volume] in Blood

741

1.61

2.62

7.2

5.0

0.59

0.58

e9/l

0.26

647

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

536

1.63

2.62

3.8

2.9

—

(3006315) Basophils [#/volume] in Blood

744

1.60

2.56

7.2

5.0

0.04

e9/l

0.25

647

(3045414) Leukocytes [Presence] in Urine

2.57

2.51

2.0

1.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

2.29

2.50

1.5

1.3

—

(3019230) Fractional oxyhemoglobin in Venous blood

3.93

2.49

1.9

75.36

58.14

—

(3013742) Prealbumin [Mass/volume] in Serum or Plasma

133

2.02

2.46

3.2

2.2

0.22

0.21

g/l

0.35

124

(3045142) Bone marrow Pathology biopsy report

5.13

2.42

2.3

1.2

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

3.05

2.32

1.5

1.8

—

(3000991) Gas panel - Venous blood

107

2.09

2.31

8.4

7.7

—

(4035726) Immunohistochemistry procedure

145

1.92

2.25

1.5

1.3

—

(3013512) EKG study

464

1.58

2.19

4.0

3.8

—

(4281824) Cell count and differential, peritoneal fluid

3.59

2.07

1.3

1.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

591

1.52

2.01

4.4

3.6

56.29

41.54

ng/l

0.26

402

(3013115) Eosinophils [#/volume] in Blood

775

1.49

1.95

8.0

5.6

0.21

0.18

e9/l

0.76

684

(4062490) Immunoglobulin typing, IgG

4.64

1.95

1.8

1.3

—

(3024928) Oxygen saturation in Venous blood

2.94

1.88

2.9

2.3

—

(3002030) Lymphocytes/100 leukocytes in Blood

721

1.48

1.88

8.3

5.3

27.54

27.78

0.07

675

(3003396) Base excess in Arterial blood by calculation

162

1.78

1.88

6.3

7.1

0.19

1.60

mmol/l

1.07

137

(3044941) Cell count panel - Synovial fluid

3.61

1.85

1.3

1.6

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

102

1.96

1.84

1.4

1.5

—

(3018010) Neutrophils/100 leukocytes in Blood

714

1.47

1.83

7.8

5.1

57.56

57.19

0.10

667

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

4.25

1.83

3.2

1.5

—

(3044927) Protein electrophoresis panel - Urine

4.25

1.83

1.0

1.1

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

117

1.90

1.83

5.3

6.1

1.34

1.31

mmol/l

0.04

112

(3000570) Elastase.pancreatic [Mass/mass] in Stool

2.42

1.81

2.0

1.3

222.33

271.36

ug/g

—

(3019225) pH of Specimen

141

1.81

1.79

5.0

3.6

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

280

1.60

1.78

1.2

1.3

12.98

30.99

iu/ml

1.81

(3002582) Erythrocytes [#/volume] in Urine

456

1.50

1.77

4.1

3.0

17.10

203.22

e6/l

0.72

351

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

747

1.46

1.76

8.8

5.6

1.21

1.22

mmol/l

0.32

627

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

3.41

1.76

1.2

—

(40768795) Lymph node Pathology biopsy report

3.41

1.76

1.8

1.0

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

2.74

1.74

1.6

1.4

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

116

986

1.47

1.74

4.8

3.0

61.75

43.84

u/l

0.78

108

925

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

3.92

1.72

3.2

1.5

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

177

1.69

1.63

10.4

6.1

105.82

104.33

mmol/l

1.74

177

(3019069) Monocytes/100 leukocytes in Blood

707

1.43

1.62

8.8

5.5

8.69

8.61

0.08

659

(3045424) Erythrocytes [Presence] in Urine

3.06

1.59

1.7

1.3

—

(3023368) Bacteria identified in Blood by Culture

420

1.48

1.58

3.8

3.6

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

2.14

1.53

1.5

2.7

1.33

0.79

g/l

0.19

(3014051) Protein [Presence] in Urine by Test strip

2.50

1.50

2.3

1.9

—

(3022096) Basophils/100 leukocytes in Blood

686

1.41

1.49

8.3

5.1

0.81

0.66

1.98

636

(40768443) Skin Pathology biopsy report

1.99

1.48

1.3

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

132

1169

1.44

1.46

5.0

4.1

14.94

14.72

pmol/l

0.45

121

1054

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

337

1.48

1.45

1.9

1.8

257500425.88

475.52

pmol/l

0.49

278

(3022145) Colonoscopy Study observation

183

1.62

1.45

1.1

1.3

—

(3052851) Hemolysis interference index of Serum or Plasma

2.37

1.45

3.8

3.4

—

(36660697) Celiac disease serology panel - Serum

120

1.75

1.41

1.3

1.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

2.47

1.40

1.9

1.4

—

(3006504) Eosinophils/100 leukocytes in Blood

702

1.39

8.3

5.2

3.40

2.69

1.39

653

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

162

1501

1.61

1.38

22.2

13.7

24.87

22.78

mg/l

0.35

144

1188

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.98

1.37

1.5

2.3

4.12

3.55

g/l

0.27

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.98

1.37

1.5

2.3

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.98

1.37

1.5

2.3

7.18

7.41

g/l

0.17

(3018095) Leukocytes [#/volume] in Urine

542

1.40

1.37

4.6

3.6

31.97

65.14

e6/l

0.93

378

(4146454) Self-monitoring of blood glucose

2.99

1.36

2.4

2.6

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

1.36

0.0

2.5

—

77.05

—

(3021788) Differential panel - Synovial fluid

2.82

1.29

1.2

1.7

—

(36304419) Bacteria [Presence] in Urine

408

1.42

1.29

4.1

2.8

—

(3000330) Specific gravity of Urine by Test strip

1.92

1.27

3.0

3.5

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.97

1.26

1.5

2.4

2.84

2.97

g/l

0.22

(3023511) Choriogonadotropin [Units/volume] in Urine

2.45

1.25

1.2

1.4

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

2.05

1.25

1.0

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

348

1.43

1.23

2.7

3.8

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

2.21

1.23

1.1

—

(40760892) CBC W Ordered Manual Differential panel - Blood

715

1.35

1.20

9.0

5.5

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

2.35

1.19

2.0

1.5

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

2.35

1.19

2.0

1.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

262

1.46

1.18

1.2

1.3

3.74

9.83

u/ml

1.06

(40761511) CBC panel - Blood by Automated count

165

1548

1.58

1.17

18.0

13.0

—

(3030467) Casts [#/volume] in Urine by Automated count

416

1.38

1.15

4.2

2.8

0.69

0.52

e6/l

0.18

309

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

2.04

1.13

1.8

1.4

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

2.04

1.13

1.5

1.3

—

(3042936) Bacteria identified in Isolate by Culture

221

1.48

1.12

3.0

1.9

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

2.42

1.09

1.2

1.4

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

2.42

1.09

1.8

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

617

1.33

1.08

2.4

2.0

104.53

98.75

pmol/l

0.32

293

(3025468) Yersinia sp identified in Specimen by Organism specific culture

2.31

1.04

1.8

1.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

2.31

1.04

1.8

1.2

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

2.31

1.04

1.8

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

2.31

1.04

1.8

1.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

2.31

1.04

1.8

1.2

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

132

0.51

1.03

1.3

1.7

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

332

1.38

1.02

1.3

0.58

1.77

u/ml

1.09

(3049717) Cytology report of Urine Cyto stain

1.92

1.02

2.2

2.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

2.21

0.98

5.0

3.2

49.68

57.90

u/ml

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

1.90

0.98

1.6

2.6

39.53

38.01

g/l

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.90

0.98

2.2

1.5

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

151

1406

1.39

0.97

6.1

4.9

2.09

1.90

mu/l

0.29

141

1274

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.82

0.96

1.5

2.4

9.96

9.91

g/l

0.02

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.79

0.92

2.9

2.4

0.50

0.69

1.59

(3021960) Folate [Moles/volume] in Serum or Plasma

385

1.33

0.90

1.9

1.6

19.68

21.84

nmol/l

0.46

313

(3009261) Glucose [Presence] in Urine by Test strip

757

1.28

0.90

3.9

3.8

0.00

estimate

-0.00

133

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

1.94

0.90

1.8

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

197

1.43

0.88

8.5

6.8

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

213

0.63

0.88

3.3

4.4

20.23

21.62

—

104

(3037467) Urinalysis macro (dipstick) panel - Urine

114

1028

1.28

0.87

4.7

4.3

—

(3025159) Blasts/100 leukocytes in Blood

113

1.56

0.85

3.6

4.6

0.00

0.03

—

(40758558) Short blood count panel - Blood

379

1.32

0.85

9.4

7.2

—

(3019060) Gas panel - Arterial blood

1.60

0.81

5.5

4.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.71

0.80

2.9

2.4

0.89

1.12

0.50

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.58

0.77

1.7

—

(1616796) Gas panel - Central venous blood

1.79

0.77

3.8

2.7

—

(3021601) Nitrite [Presence] in Urine by Test strip

750

1.25

0.75

5.5

5.2

0.00

estimate

-0.00

141

(3021440) Promyelocytes/100 leukocytes in Blood

117

1.50

0.75

3.8

4.5

0.00

0.10

—

(3020891) Body temperature

1.64

0.73

7.1

3.5

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

126

1.47

0.73

2.7

2.8

72.33

68.24

ml/min/173m2

—

(3017181) Myelocytes/100 leukocytes in Blood

126

1.47

0.73

3.8

4.3

0.86

0.87

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

1.83

0.73

1.6

2.3

1.49

1.48

mg/l

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

1.83

0.73

1.0

1.2

—

(42870365) C reactive protein [Mass/volume] in Blood by High sensitivity method

2.03

0.73

2.6

2.7

—

20.14

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

645

1.24

0.72

3.3

2.2

80.76

78.25

nmol/l

0.32

560

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.58

0.71

1.0

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

215

1.36

0.70

3.5

1.8

27.43

29.37

1.94

209

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.68

0.70

1.3

1.6

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.68

0.70

1.7

1.9

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

298

1.30

0.68

2.4

2.9

2.46

mmol/l

0.02

258

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

244

1.32

0.67

2.0

1.8

—

(21494755) Public health laboratory ask at order entry panel

129

0.60

0.66

1.1

1.3

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

152

1442

1.30

0.65

19.3

13.1

76.72

79.88

ml/min/173m2

0.87

131

1175

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

1.58

0.63

7.5

9.0

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

140

1.40

0.61

1.7

1.3

—

(3007164) IgA [Mass/volume] in Serum or Plasma

312

1.27

0.61

1.8

1.4

2.05

2.51

g/l

0.60

185

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.59

0.0

1.1

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

304

1.27

0.59

4.2

3.7

333.09

183.71

ng/l

0.27

235

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

1.55

0.56

1.4

—

(40761536) Microorganisms panel - Urine sediment

135

0.65

0.54

8.7

3.5

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

171

1.32

0.53

9.7

4.1

248.27

247.82

u/l

0.01

159

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

267

0.76

0.52

1.7

1.4

—

(3026782) Osmolality of Urine

301

1.24

0.50

3.4

2.8

505.41

526.45

mosm/kgh2o

0.20

261

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

164

1.32

0.49

2.0

1.7

—

(3002179) Metamyelocytes/100 leukocytes in Blood

111

1.38

0.48

4.0

4.5

0.33

0.83

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

1.48

0.47

2.3

4.8

151.16

219.10

mg/l

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.48

0.47

1.0

1.8

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

1.48

0.47

2.3

4.9

25.51

24.30

mg/l

—

(3000850) Epithelial cells [#/volume] in Urine

305

1.22

0.45

3.6

2.6

3.85

5.64

e6/l

1.03

277

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.40

0.45

1.1

1.3

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.39

0.44

1.4

1.5

—

(3010813) Leukocytes [#/volume] in Blood

170

1654

1.32

0.44

31.7

20.7

6.99

6.61

e9/l

1.23

164

1592

(3009542) Hematocrit [Volume Fraction] of Blood

170

1654

1.32

0.44

31.4

20.7

39.27

39.78

0.85

161

1560

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

1.63

0.43

1.4

1.5

—

(3037756) Immunofixation for Serum or Plasma

1.63

0.43

2.0

1.7

—

(3026361) Erythrocytes [#/volume] in Blood

170

1655

1.32

0.43

31.6

20.7

4.34

4.43

e12/l

1.67

165

1596

(3041096) Erythrocytes [Presence] in Urine by Automated

418

0.83

0.42

5.1

3.4

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.58

0.42

1.0

1.2

—

(3019309) Folate [Moles/volume] in Red Blood Cells

298

1.21

0.42

2.2

1.7

1196.17

1224.97

nmol/l

0.06

223

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

149

0.72

0.42

1.3

1.8

—

(40760888) Immunoglobulin light chains.free panel - Serum

1.53

0.41

1.4

5.9

—

(3010726) Horse dander IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

0.10

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

18.7

—

969.33

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

25.9

—

1879.53

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

0.41

0.0

1.0

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.40

0.0

1.9

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.40

0.0

1.6

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

1.35

0.38

1.2

1.4

—

42.91

—

(3022621) pH of Urine by Test strip

108

1.32

0.36

2.6

2.8

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

145

1399

1.17

0.34

6.1

5.6

39.96

39.65

mmol/mol

0.16

134

1305

(3035350) Ketones [Presence] in Urine by Test strip

753

1.13

0.33

4.0

3.8

0.00

estimate

-0.00

151

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.33

0.30

1.3

1.5

—

(3044889) 12 lead EKG panel

110

1047

1.12

0.30

4.3

3.9

—

(3007853) Bacteria identified in Skin by Aerobe culture

167

1.22

0.30

2.0

1.6

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

145

1404

1.15

0.29

4.2

4.0

1.26

mmol/l

0.06

135

1284

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

140

0.77

0.29

1.5

1.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

299

0.85

0.28

1.3

1.4

—

(3025941) Bacteria identified in Stool by Culture

1.28

0.27

1.3

1.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

160

1.21

0.26

3.9

3.6

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

151

1470

1.14

0.26

4.7

4.5

4.72

4.73

mmol/l

0.02

141

1354

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.28

0.25

1.7

1.3

—

(4200892) Spirometry reversibility

106

1.24

0.24

1.2

1.4

—

(40768797) Stomach Pathology biopsy report

219

1.16

0.23

1.2

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

1.32

0.23

1.0

1.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.76

0.23

1.1

1.3

—

(1761482) Bacteria [#/volume] in Urine by Culture

1.23

0.22

10.4

4.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

150

1465

1.12

0.21

5.1

4.6

5.82

5.90

mmol/l

0.32

141

1343

(3004915) Chlamydophila pneumoniae IgA Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3016750) Collection duration of Urine

0.00

0.21

0.0

2.3

—

494.67

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

0.21

0.0

1.4

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.21

0.0

1.1

—

(3020013) Alkaline phosphatase.intestinal [Enzymatic activity/volume] in Serum or Plasma

0.00

0.21

0.0

1.7

—

9.34

—

(3004451) EKG impression Narrative

0.00

0.21

0.0

1.3

—

(3015024) Glucose [Moles/volume] in Serum or Plasma --1 hour post dose glucose

0.00

0.21

0.0

1.6

—

7.36

—

(3004775) Volume in Urine collected for unspecified duration

0.00

0.21

0.0

2.4

—

643.17

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.8

—

67.08

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

1.17

0.21

1.6

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

919

1.09

0.21

3.4

3.0

—

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

123

0.80

0.21

4.3

4.1

1.21

1.23

mmol/l

—

108

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid

0.00

0.20

0.0

1.0

—

515.89

—

(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.20

0.0

1.0

—

32.22

—

(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid

0.00

0.20

0.0

1.0

—

228.33

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

226

0.87

0.18

1.8

1.6

—

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.19

0.18

2.4

1.8

—

(3020682) Albumin/Creatinine [Ratio] in Urine

438

1.10

0.18

4.2

3.6

15.18

6.87

mg/mmol

0.65

255

(1761868) Lipid panel - Serum or Plasma

492

0.91

0.17

2.9

3.1

—

(3009508) Creatinine [Moles/volume] in Urine

439

1.09

0.17

3.3

2.9

6.62

7.15

mmol/l

0.46

360

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.18

0.17

2.3

2.1

38.00

41.61

u/l

—

(3012516) Albumin [Mass/volume] in Urine

420

1.09

0.17

3.6

3.0

88.75

361.08

mg/l

0.64

259

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.78

0.15

1.1

1.0

—

(3018418) pH of Serum or Plasma

464

1.08

0.13

7.6

3.7

7.39

7.40

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

184

1.10

0.09

1.9

1.5

—

(3026008) Bacteria identified in Urine by Culture

510

1.05

0.09

3.1

2.9

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

1.05

0.08

1.2

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

1.05

0.08

1.2

—

(42529406) Shigella sp [Presence] in Stool by Culture

1.04

0.08

1.2

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

123

0.89

0.08

1.7

—

(3021589) Normoblasts [#/volume] in Blood

670

1.05

0.08

11.7

9.3

0.00

e9/l

1.22

546

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

1.04

0.07

3.0

2.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

118

1.11

0.07

1.2

1.3

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

148

1464

1.05

0.07

4.6

4.5

1.52

1.54

mmol/l

0.21

138

1341

(3019832) Treponema pallidum Ab [Presence] in Serum

0.86

0.07

1.1

1.7

—

(3000492) Spirometry study

129

1.09

0.06

1.3

1.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

583

0.97

0.04

4.4

4.0

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

170

1.07

0.04

2.2

1.8

—

(3003694) ABO and Rh group [Type] in Blood

390

1.03

0.03

1.5

1.4

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

411

1.03

0.02

1.5

1.7

1.60

1.32

mmol/l

0.63

342

(3000494) Fungus identified in Specimen by Culture

187

0.96

0.01

1.4

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

150

1501

1.00

0.00

5.3

5.0

2.74

2.79

mmol/l

0.24

139

1374

(3029937) Albumin [Presence] in Urine by Test strip

417

1.01

0.00

4.0

0.00

estimate

-0.00

138

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.0

1.1

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.4

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

0.0

7.3

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

4.5

—

(3036185) Alkaline phosphatase.liver 2 [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.3

—

20.14

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(3043410) Blood group antigens tested for on Red Blood Cells

0.00

0.0

1.3

—

(3035062) Alkaline phosphatase.liver 1 [Enzymatic activity/volume] in Serum or Plasma

0.00

0.0

1.3

—

59.49

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

0.0

4.5

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.0

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

8.4

—

(42868766) Dientamoeba fragilis DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3045716) Anion gap in Serum or Plasma

0.00

-0.00

0.0

1.0

—

7.50

—

(3020911) Cortisol [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.7

—

65.86

—

(4034850) Laboratory test

0.94

-0.00

13.8

10.3

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3008898) HLA-B27 [Presence]

0.94

-0.00

1.0

1.1

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.97

-0.00

1.3

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.2

—

1.21

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3011436) Histone Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3029023) Hepatitis E virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1937.80

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3001964) Herpes simplex virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.5

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

3.4

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.3

—

(3002222) Hepatitis E virus IgM Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

-0.00

0.0

1.0

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.3

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3006922) Hepatitis E virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3029536) Hepatitis C virus RNA [Units/volume] (viral load) in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

229.43

—

Mortality – FinRegistry

↥

Association

Association between endpoint CD2_BENIGN_RETROPERITONEUM_PERITONEUM and mortality.

Females

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RETROPERITONEUM_PERITONEUM	2.385 [1.89, 3.01]	< 0.001
Birth year	0.993 [0.98, 1.0]	0.1

During the follow-up period (1.1.1998 — 31.12.2019), 150 out of 605 females with CD2_BENIGN_RETROPERITONEUM_PERITONEUM died.

Males

Parameter	HR [95% CI]	p-value
CD2_BENIGN_RETROPERITONEUM_PERITONEUM	1.881 [1.45, 2.44]	< 0.001
Birth year	0.987 [0.98, 1.0]	0.007

During the follow-up period (1.1.1998 — 31.12.2019), 136 out of 336 males with CD2_BENIGN_RETROPERITONEUM_PERITONEUM died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_RETROPERITONEUM_PERITONEUM.

N-year risk	Females	Males
1	0.204%	0.449%
5	1.191%	2.385%
10	3.436%	5.42%
15	6.315%	9.864%
20	10.745%	16.087%

Relationships between endpoints

↥

Index endpoint: CD2_BENIGN_RETROPERITONEUM_PERITONEUM – Benign neoplasm of soft tissue of retroperitoneum and peritoneum

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Benign neoplasm of soft tissue of retroperitoneum and peritoneum

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints