Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

N14_OTHNONINFOVA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N83.8, N83.9
  • Hospital discharge: ICD-9 6206
  • Cause of death: ICD-10 N83.8, N83.9
  • Cause of death: ICD-9 6206

2 out of 7 registries used, show all original rules.

1119

4. Check minimum number of events

None

1119

5. Include endpoints

None

1119

6. Filter based on genotype QC (FinnGen only)

1119

Control definitions (FinnGen only)

Control exclude
N14_FEMALEGENNONINF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 6581 6581 -
Only index persons 6474 6474 -
Unadjusted period prevalence (%)
Whole population 0.19 0.19 -
Only index persons 0.24 0.24 -
Median age at first event (years)
Whole population - 39.88 -
Only index persons - 39.75 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1119 1119 -
Unadjusted period prevalence (%) 0.38 0.38 -
Median age at first event (years) 42.66 42.66 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1000
Matched controls
10000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N83.9
ICD-10 Finland
Noninflammatory disorder of ovary, fallopian tube and broad ligament, unspecified
5965.7
323.0
504
*
N83.8
ICD-10 Finland
Other noninflammatory disorders of ovary, fallopian tube and broad ligament
5205.9
323.0
477
*
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
114.0
323.0
431
66
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
11.3
259.5
663
1477
N95.1
ICD-10 Finland
Menopausal and female climacteric states
+∞
112.7
106
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
5.1
105.9
425
1262
LCA06
NOMESCO Finland
Biopsy of endometrium
11.7
100.4
197
206
N80.1
ICD-10 Finland
Endometriosis of ovary
974.0
92.4
89
*
N84.0
ICD-10 Finland
Polyp of corpus uteri
166.6
87.7
91
6
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
13.9
86.5
154
129
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
878.5
83.8
81
*
N97.9
ICD-10 Finland
Female infertility, unspecified
55.5
76.9
91
18
JAH01
NOMESCO Finland
Laparoscopy
13.0
70.0
128
112
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
31.5
69.0
92
32
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.3
66.2
479
2169
N80.9
ICD-10 Finland
Endometriosis, unspecified
115.7
60.6
65
6
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
51.6
60.2
72
15
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
7.2
56.1
145
231
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
13.1
55.4
100
84
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
4.7
52.7
200
506
ULC02
NOMESCO Finland
Hysteroscopy
19.1
52.4
81
46
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
4.9
52.1
189
456
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
4.8
51.2
188
459
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
14.1
50.5
88
68
LAC01
NOMESCO Finland
Laparoscopic excision of ovarian cyst
61.4
50.0
58
10
N97.8
ICD-10 Finland
Female infertility of other origin
+∞
49.4
47
*
LAF11
NOMESCO Finland
Laparoscopic bilateral salpingo-oophorectomy
11.2
48.9
95
93
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
20.1
48.2
73
39
N95.2
ICD-10 Finland
Postmenopausal atrophic vaginitis
+∞
47.3
45
*
LCA13
NOMESCO Finland
Curettage of cervix and body of uterus
25.1
46.8
66
28
N95.0
ICD-10 Finland
Postmenopausal bleeding
20.8
46.8
70
36
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
14.3
44.2
76
57
N83.1
ICD-10 Finland
Corpus luteum cyst
117.7
42.1
45
*
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
89.8
39.1
43
5
N80.0
ICD-10 Finland
Endometriosis of uterus
138.7
38.0
40
*
D39.10
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary without histology
11.0
37.6
73
71
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
+∞
36.7
35
*
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
+∞
36.7
35
*
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
56.0
36.6
43
8
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
7.6
36.1
87
123
TLC00
NOMESCO Finland
Insertion of intrauterine device
6.1
35.7
102
183
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
98.7
35.0
38
*
LCB25
NOMESCO Finland
Hysteroscopic excision of lesion
19.2
34.8
53
29
N97.1
ICD-10 Finland
Female infertility of tubal origin
+∞
34.6
33
*
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
93.3
32.9
36
*
P01AB01
ATC
metronidazole; oral, rectal
2.3
32.8
462
2732
N83.0
ICD-10 Finland
Follicular cyst of ovary
35.5
32.1
41
12
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
+∞
31.4
30
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.2
31.2
479
2925
N81.6
ICD-10 Finland
Rectocele
16.4
31.0
50
32
TLW10
NOMESCO Finland
Transfer of fresh embryo
+∞
30.4
29
*
N81.1
ICD-10 Finland
Cystocele
20.4
30.2
45
23
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
110.1
29.8
32
*
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
20.9
29.8
44
22
XLA10
NOMESCO Finland
NA
5.6
29.3
89
172
N92.4
ICD-10 Finland
Excessive bleeding in the premenopausal period
26.0
29.0
40
16
6206A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Broad ligament laceration syndrome
+∞
28.3
27
*
TLW00
NOMESCO Finland
Insemination
289.2
27.9
28
*
G03GA01
ATC
chorionic gonadotrophin; parenteral
6.9
27.7
71
110
B02AA02
ATC
tranexamic acid; systemic
3.0
27.4
182
700
N83.5
ICD-10 Finland
Torsion of ovary, ovarian pedicle and fallopian tube
+∞
27.2
26
*
8113
FHL
Fractional scraping
9.9
26.2
53
56
N87.0
ICD-10 Finland
Mild cervical dysplasia
138.6
25.7
27
*
LAA06
NOMESCO Finland
Transvaginal puncture of ovarian cyst
138.6
25.7
27
*
N02BE01
ATC
paracetamol; systemic, rectal
2.5
25.2
861
7140
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
15.4
24.4
40
27
TLW12
NOMESCO Finland
Insertion of frozen embryo
+∞
24.1
23
*
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
+∞
24.1
23
*
D25.9
ICD-10 Finland
Leiomyoma of uterus, unspecified
3.6
23.8
115
350
N97.4
ICD-10 Finland
Female infertility associated with male factors
245.6
23.7
24
*
J02AC01
ATC
fluconazole; systemic
2.0
23.7
513
3471
G03GA06
ATC
follitropin beta; parenteral
9.6
23.5
48
52
LEF00
NOMESCO Finland
Anterior colporraphy with sutures for primary cystocele
235.1
22.7
23
*
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
13.7
21.6
37
28
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
27.1
21.4
29
11
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
2.2
21.2
248
1286
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
21.2
252
1318
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.3
21.1
232
1170
N97.0
ICD-10 Finland
Female infertility associated with anovulation
61.4
20.9
24
*
N84.1
ICD-10 Finland
Polyp of cervix uteri
26.1
20.5
28
11
H01CA02
ATC
nafarelin; nasal
10.6
20.2
39
38
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.9
20.1
503
3507
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
+∞
19.9
19
*
A02BC02
ATC
pantoprazole; systemic
1.9
19.7
598
4445
LCA16
NOMESCO Finland
Destruction of endometrium
203.8
19.6
20
*
LAC31
NOMESCO Finland
Laparoscopic excision of paraovarian cyst
203.8
19.6
20
*
LCD00
NOMESCO Finland
Hysterectomy
4.4
19.2
72
175
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
12.5
19.2
34
28
LCA10
NOMESCO Finland
Curettage of body of uterus
14.3
19.1
32
23
M01AE02
ATC
naproxen; oral, rectal
1.8
19.1
584
4328
LEF13
NOMESCO Finland
Colpoperineoplasty and vaginal hysterectomy
+∞
18.8
18
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
+∞
18.8
18
*
H01CC01
ATC
ganirelix; parenteral
7.3
18.8
45
64
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
5.2
18.5
58
117
G03GA05
ATC
follitropin alfa; parenteral
8.0
18.2
41
53
LCD04
NOMESCO Finland
Laparoscopic hysterectomy
6.6
18.0
46
72
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
18.0
254
1418
TLC02
NOMESCO Finland
Simple extraction of IUD
4.2
17.8
68
169
N85.9
ICD-10 Finland
Noninflammatory disorder of uterus, unspecified
+∞
17.8
17
*
N85.0
ICD-10 Finland
Endometrial glandular hyperplasia
96.8
17.6
19
*
J01DB01
ATC
cefalexin; oral
2.0
17.4
802
6728
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
17.3
207
1074
R51.80
ICD-10 Finland
Headache
2.3
17.1
170
808
N02AX02
ATC
tramadol; systemic, rectal
1.9
16.9
343
2184
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.9
16.8
110
414
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
+∞
16.7
16
*
Z31.2
ICD-10 Finland
In vitrofertilization
+∞
16.7
16
*
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
23.5
16.5
23
10
J01MA02
ATC
ciprofloxacin; systemic
1.9
16.4
325
2049
L02AE02
ATC
leuprorelin; implant, parenteral
8.6
16.3
35
42
LCD10
NOMESCO Finland
Vaginal hysterectomy
8.4
16.1
35
43
M03BC01
ATC
orphenadrine (citrate); systemic
1.9
15.6
257
1509
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
8.7
15.6
33
39
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
162.4
15.5
16
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
15.4
300
1869
M54.5
ICD-10 Finland
Low back pain
1.8
15.4
317
2016
A02BC05
ATC
esomeprazole; systemic
1.8
15.2
365
2442
G03DB01
ATC
dydrogesterone; oral
2.1
15.0
182
945
D01
ICPC
Abdominal pain/cramps general
2.5
15.0
127
555
Z71.8
ICD-10 Finland
Other specified counselling
1.9
14.7
252
1500
N98.1
ICD-10 Finland
Hyperstimulation of ovaries
+∞
14.6
14
*
LAC00
NOMESCO Finland
Excision of ovarian cyst
81.3
14.6
16
*
N80.81
ICD-10 Finland
Endometriosis in sacrouteral ligament
152.1
14.5
15
*
J01CA08
ATC
pivmecillinam; oral
1.7
14.0
515
3874
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.3
14.0
141
670
G03DA04
ATC
progesterone; systemic, rectal, vaginal
4.6
13.8
48
109
D27.91
ICD-10 Finland
Benign epithelial tumor of the ovary (ovary)
7.5
13.8
32
44
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
6.6
13.8
35
55
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
13.7
161
823
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
5.4
13.6
40
76
N80.5
ICD-10 Finland
Endometriosis of intestine
+∞
13.6
13
*
D27.99
ICD-10 Finland
Benign tumor of the ovary (ovary), unspecified histology
26.1
13.4
18
7
ULA02
NOMESCO Finland
Kolposcopy
2.6
13.4
101
415
R03AC02
ATC
salbutamol; inhalant
1.7
13.3
505
3811
J01AA02
ATC
doxycycline; systemic
1.7
13.3
737
6188
N03AX16
ATC
pregabalin; oral
1.9
13.2
204
1163
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
13.1
95
381
M01AH05
ATC
etoricoxib; oral
1.6
12.9
551
4279
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
12.8
65
207
H02AB06
ATC
prednisolone; systemic
1.7
12.7
419
3030
M01AB05
ATC
diclofenac; systemic, rectal
1.6
12.7
617
4954
R19.0
ICD-10 Finland
Intra-abdominal and pelvic swelling, mass and lump
4.6
12.7
43
96
N70.9
ICD-10 Finland
Salpingitis and oophoritis, unspecified
32.5
12.6
16
5
6173B
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS RETROUTERINA]
+∞
12.5
12
*
62699
ICD-8 Finland
Disorders of menstruation, Other
+∞
12.5
12
*
LCF01
NOMESCO Finland
Laparoscopic excision of lesion of parametrium
+∞
12.5
12
*
6262A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Excessive or frequent menstruation[HYPERMENORRHOEA]
+∞
12.5
12
*
LBE00
NOMESCO Finland
Salpingectomy
20.3
12.5
18
9
G03GA02
ATC
human menopausal gonadotrophin; parenteral
5.7
12.5
35
63
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
12.4
411
2975
J01EA01
ATC
trimethoprim; systemic
1.8
12.3
269
1722
D06
ICPC
Abdominal pain localized other
2.6
12.2
93
382
N94.4
ICD-10 Finland
Primary dysmenorrhoea
7.1
12.2
29
42
R07.3
ICD-10 Finland
Other chest pain
2.7
12.0
82
317
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
12.0
198
1154
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.0
11.9
158
846
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.6
11.9
91
375
M01AE01
ATC
ibuprofen; systemic, rectal
2.0
11.9
901
8161
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
11.8
111
511
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
11.8
161
869
N70.0
ICD-10 Finland
Acute salpingitis and oophoritis
10.7
11.8
22
21
R74
ICPC
Upper respiratory infection acute
1.7
11.8
344
2392
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
11.7
157
845
M79.6
ICD-10 Finland
Pain in limb
1.7
11.7
323
2212
N83.3
ICD-10 Finland
Acquired atrophy of ovary and fallopian tube
+∞
11.5
11
*
M54.2
ICD-10 Finland
Cervicalgia
2.8
11.4
75
285
R01AD09
ATC
mometasone; nasal
1.6
11.4
456
3443
N30.0
ICD-10 Finland
Acute cystitis
2.0
11.2
149
799
UKC02
NOMESCO Finland
Cystoscopy
2.7
11.2
80
317
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
11.1
182
1055
G44.2
ICD-10 Finland
Tension-type headache
2.1
11.1
138
720
M03BX02
ATC
tizanidine; oral
1.6
11.0
593
4799
K30
ICD-10 Finland
Functional dyspepsia
2.3
11.0
105
487
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
11.0
247
1588
N03AX12
ATC
gabapentin; oral
2.1
10.9
135
699
N80
ICD-10 Finland
Endometriosis
43.8
10.9
13
*
J01DA01
ATC
[U] cefalexin; systemic
1.6
10.7
598
4865
Z30.2
ICD-10 Finland
Sterilization
2.1
10.6
131
683
D39.19
ICD-10 Finland
Tumor of uncertain or unknown nature in the ovary with unspecified histology
10.2
10.5
20
20
ZXD05
NOMESCO Finland
Urgent procedure
1.7
10.5
298
2044
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.1
10.5
57
192
LA2JE
NOMESCO Finland
Follow-up of menstrual cycle with repeated measurement of ovarian cyst
+∞
10.4
10
*
6200A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Follicular cyst of ovary
+∞
10.4
10
*
TLW14
NOMESCO Finland
ICSI
+∞
10.4
10
*
N95.8
ICD-10 Finland
Other specified menopausal and perimenopausal disorders
+∞
10.4
10
*
N85.1
ICD-10 Finland
Endometrial adenomatous hyperplasia
+∞
10.4
10
*
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
+∞
10.4
10
*
LCA30
NOMESCO Finland
Transfer of oocyte or embryo to uterus in assisted fertilisation
+∞
10.4
10
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
10.4
327
2304
LDA10
NOMESCO Finland
Curettage of cervix uteri
3.3
10.3
51
160
A02BC04
ATC
rabeprazole; oral
2.4
10.3
85
367
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
10.3
480
3728
G03DC02
ATC
norethisterone; oral
2.1
10.2
120
610
R93.5
ICD-10 Finland
Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
7.6
10.2
23
31
LDB00
NOMESCO Finland
Excision of lesion of cervix uteri
13.3
10.2
17
13
UJF32
NOMESCO Finland
Coloscopy
1.8
10.1
179
1062
Q50.5
ICD-10 Finland
Embryonic cyst of broad ligament
40.5
10.0
12
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.0
305
2130
N94.6
ICD-10 Finland
Dysmenorrhoea, unspecified
6.8
9.9
24
36
N05CF01
ATC
zopiclone; oral
1.7
9.9
254
1688
ZXD20
NOMESCO Finland
Day surgery
2.1
9.8
117
600
1410
FHL
Laparoscopy
5.0
9.8
30
61
R06.0
ICD-10 Finland
Dyspnoea
1.8
9.8
186
1129
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
2.2
9.7
103
500
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
9.7
311
2195
R50.9
ICD-10 Finland
Fever, unspecified
2.0
9.6
122
641
A02BC01
ATC
omeprazole; systemic
1.7
9.6
215
1373
M79.1
ICD-10 Finland
Myalgia
2.0
9.5
131
710
G43.9
ICD-10 Finland
Migraine, unspecified
2.4
9.4
82
363
LA2HE
NOMESCO Finland
Repeated measurement of ovarian cyst
100.9
9.4
10
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
9.4
110
558
N80.2
ICD-10 Finland
Endometriosis of fallopian tube
+∞
9.4
9
*
N91.1
ICD-10 Finland
Secondary amenorrhoea
8.1
9.4
20
25
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
2.6
9.3
67
269
D25.1
ICD-10 Finland
Intramural leiomyoma of uterus
3.0
9.2
53
185
D25.0
ICD-10 Finland
Submucous leiomyoma of uterus
4.9
9.0
28
58
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.9
9.0
53
189
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.0
484
3841
M01AC06
ATC
meloxicam; systemic, rectal
1.6
8.9
320
2312
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
24.2
8.9
12
5
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
8.9
302
2153
LAE11
NOMESCO Finland
Unilateral laparoscopic oophorectomy
12.7
8.9
15
12
N94.1
ICD-10 Finland
Dyspareunia
12.7
8.9
15
12
1413
FHL
Laparoscopy and other therapeutic procedure
6.4
8.8
22
35
L02AE01
ATC
buserelin; implant, nasal, parenteral
9.6
8.8
17
18
O00.1
ICD-10 Finland
Tubal pregnancy
4.8
8.8
28
60
R10.2
ICD-10 Finland
Pelvic and perineal pain
4.9
8.7
27
56
N93.9
ICD-10 Finland
Abnormal uterine and vaginal bleeding, unspecified
7.7
8.7
19
25
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
8.6
155
923
A02BA02
ATC
ranitidine; systemic
1.8
8.6
148
867
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
10.1
8.5
16
16
N76.0
ICD-10 Finland
Acute vaginitis
2.3
8.5
76
341
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
8.5
64
263
U02
ICPC
Urinary frequency/urgency
1.9
8.5
128
716
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
8.5
159
960
61520
ICD-8 Finland
Other diseases of ovary and Fallopian tube, Cysta (cystis) follicularis ovarii (retentio)
+∞
8.3
8
*
6170A
ICD-9 Finland
Endometriosis of uterus
+∞
8.3
8
*
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
+∞
8.3
8
*
62800
ICD-8 Finland
Sterility, female, Sterilitas primaria
+∞
8.3
8
*
62532
ICD-8 Finland
Other diseases of uterus, Endometriosis retro-cervicalis sive retrouterina
+∞
8.3
8
*
J01FA10
ATC
azithromycin; systemic
1.5
8.3
588
4908
KH1AD
NOMESCO Finland
CT of urinary organs
3.9
8.3
32
83
J01CA04
ATC
amoxicillin; systemic
1.6
8.3
806
7219
C07AB07
ATC
bisoprolol; oral
1.5
8.3
304
2200
N06AX21
ATC
duloxetine; oral
2.1
8.2
98
503
G01AF01
ATC
metronidazole; vaginal
1.9
8.2
121
673
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
8.2
113
610
J01FA09
ATC
clarithromycin; systemic
1.5
8.2
298
2151
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.9
8.0
119
661
LAD01
NOMESCO Finland
Laparoscopic partial excision of ovary
22.2
8.0
11
5
SPAT1263
SPAT
Sampling
1.5
8.0
381
2917
6421
FHL
Appendicectomy
2.7
8.0
54
208
LAF10
NOMESCO Finland
Bilateral salpingo-oophorectomy
3.5
8.0
36
107
R42
ICD-10 Finland
Dizziness and giddiness
1.7
7.9
164
1021
A03CA02
ATC
clidinium and psycholeptics; oral
2.9
7.9
46
163
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.6
7.9
55
218
M01AX17
ATC
nimesulide; oral
1.7
7.9
179
1144
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
7.9
509
4152
R01AD08
ATC
fluticasone; nasal
1.5
7.8
277
1986
SPAT1240
SPAT
Therapeutic discussion
1.8
7.7
126
726
Z09.9
ICD-10 Finland
Follow-up examination after unspecified treatment for other conditions
6.4
7.7
19
30
N81.5
ICD-10 Finland
Vaginal enterocele
45.3
7.7
9
*
WX110
NOMESCO Finland
Local anesthesy
1.5
7.7
653
5615
N06AX16
ATC
venlafaxine; oral
1.8
7.6
134
792
R20.2
ICD-10 Finland
Paraesthesia of skin
2.4
7.6
65
286
M54.6
ICD-10 Finland
Pain in thoracic spine
2.4
7.6
65
286
R51.81
ICD-10 Finland
Facial pain NOS
4.2
7.6
27
65
R00.0
ICD-10 Finland
Tachycardia, unspecified
2.8
7.6
48
177
D25.2
ICD-10 Finland
Subserosal leiomyoma of uterus
4.1
7.6
28
70
LCA96
NOMESCO Finland
Other intrauterine operation
18.5
7.6
11
6
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
7.5
690
6009
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
7.5
104
565
N02AA05
ATC
oxycodone; systemic
2.0
7.5
96
508
Q50.10
ICD-10 Finland
A developmental cyst in the ovary
6.5
7.4
18
28
8119
FHL
Other measure in this category
80.7
7.4
8
*
K08.80
ICD-10 Finland
Toothache NOS
2.1
7.4
83
415
Z3231
NOMESCO Finland
Registered nurse
1.6
7.4
206
1391
R11
ICD-10 Finland
Nausea and vomiting
2.1
7.4
78
380
N01
ICPC
Headache
1.9
7.4
114
645
C07AA05
ATC
propranolol; systemic
1.6
7.3
188
1240
6289A
ICD-9 Finland
Infertility, female, Of unspecified origin[STERILITAS ET INFERTILITAS MULIERIS NUD PRIM]
+∞
7.3
7
*
62698
ICD-8 Finland
Disorders of menstruation, Alia definita
+∞
7.3
7
*
6282A
ICD-9 Finland
Infertility, female, Of tubal origin[STERIL ET INFERT EX ORIG TUBAE UTERINAE PRIM]
+∞
7.3
7
*
N81.3
ICD-10 Finland
Complete uterovaginal prolapse
+∞
7.3
7
*
N93.8
ICD-10 Finland
Other specified abnormal uterine and vaginal bleeding
9.4
7.3
14
15
J05AB01
ATC
aciclovir; systemic
1.6
7.3
198
1328
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
4.7
7.2
23
50
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
2.4
7.2
59
253
JEA00
NOMESCO Finland
Appendectomy
2.3
7.2
65
295
LBE20
NOMESCO Finland
Laparoscopic bilateral salpingectomy
7.4
7.2
16
22
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
7.2
75
365
R06AX27
ATC
desloratadine; oral
1.5
7.1
279
2035
R03DC03
ATC
montelukast; oral
1.7
7.1
155
974
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
6.1
7.1
18
30
J01MA12
ATC
levofloxacin; systemic
1.8
7.1
129
772
R03BA05
ATC
fluticasone; inhalant
1.7
7.0
162
1038
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
7.0
323
2443
ZXE00
NOMESCO Finland
One hour or less
1.5
6.9
338
2584
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
6.9
358
2773
R2110
NOMESCO Finland
Giving the first information
2.2
6.9
65
302
N06AX11
ATC
mirtazapine; oral
1.5
6.8
258
1869
N03AX11
ATC
topiramate; oral
3.3
6.8
32
99
O00.9
ICD-10 Finland
Ectopic pregnancy, unspecified
5.1
6.8
20
40
A11
ICPC
Chest pain NOS
2.4
6.8
55
238
M70.6
ICD-10 Finland
Trochanteric bursitis
1.9
6.8
102
570
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
6.8
509
4224
R09
ICPC
Sinus symptom/complaint
2.0
6.7
88
469
G03DC03
ATC
lynestrenol; oral
3.8
6.7
26
69
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.6
6.7
210
1456
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.2
6.7
67
321
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
3.5
6.6
29
85
WX400
NOMESCO Finland
Inhalation anesthesy
2.6
6.6
44
171
H02AB04
ATC
methylprednisolone; systemic
1.8
6.6
123
738
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
6.6
301
2265
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.2
6.5
65
308
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
3.3
6.5
30
92
G01AF04
ATC
miconazole; vaginal
2.3
6.4
58
265
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
6.4
636
5523
R21
ICPC
Throat symptom/complaint
1.5
6.4
210
1470
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.1
6.4
72
362
LBF00
NOMESCO Finland
Perfusion of Fallopian tube
70.3
6.4
7
*
Z01.2
ICD-10 Finland
Dental examination
1.4
6.4
388
3082
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
6.4
551
4668
M01AG02
ATC
tolfenamic acid; oral, rectal
1.6
6.4
170
1131
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.5
6.3
223
1591
G04BD08
ATC
solifenacin; oral
2.7
6.3
41
158
62530
ICD-8 Finland
Other diseases of uterus, Endometriosis ovarii
+∞
6.3
6
*
G03GA30
ATC
gonadotropins - combinations; systemic
+∞
6.3
6
*
N84.2
ICD-10 Finland
Polyp of vagina
+∞
6.3
6
*
N88.2
ICD-10 Finland
Stricture and stenosis of cervix uteri
+∞
6.3
6
*
N80.8
ICD-10 Finland
Other endometriosis
+∞
6.3
6
*
A03
ICPC
Fever
1.6
6.3
156
1022
G01AA10
ATC
clindamycin; vaginal
1.6
6.2
183
1245
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
6.2
56
255
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
6.2
244
1778
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.4
6.2
28
85
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
6.2
211
1493
J01FA06
ATC
roxithromycin; oral
1.4
6.1
356
2800
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.6
6.1
25
70
L86
ICPC
Back syndrome with radiating pain
2.4
6.1
48
206
J01FF01
ATC
clindamycin; systemic
1.5
6.1
210
1483
N30.9
ICD-10 Finland
Cystitis, unspecified
2.3
6.1
52
230
WX290
NOMESCO Finland
Other blockade of nerve
1.4
6.1
442
3620
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
8.7
6.1
12
14
A02BC03
ATC
lansoprazole; oral
1.5
6.1
211
1494
A63.0
ICD-10 Finland
Anogenital (venereal) warts
2.6
6.0
40
156
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
6.0
62
301

Mortality – FinRegistry

Association

Association between endpoint N14_OTHNONINFOVA and mortality.

Females

Parameter HR [95% CI] p-value
N14_OTHNONINFOVA 1.184 [1.02, 1.38] 0.029
Birth year 0.994 [0.99, 1.0] 0.195

During the follow-up period (1.1.1998 — 31.12.2019), 317 out of 5661 females with N14_OTHNONINFOVA died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_OTHNONINFOVA.

N-year risk Females Males
1 0.093% No data
5 0.606% No data
10 1.766% No data
15 3.405% No data
20 5.588% No data

Relationships between endpoints

Index endpoint: N14_OTHNONINFOVA – Other and unspecified noninflammatory disorders of ovary, fallopian tube and broad ligament

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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