Maternal care for (suspected) damage to fetus from alcohol

MATERNCAREFETUSALCO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O35.4
  • Cause of death: ICD-10 O35.4

2 out of 7 registries used, show all original rules.

124

4. Check minimum number of events

None

124

5. Include endpoints

None

124

6. Filter based on genotype QC (FinnGen only)

115

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
2
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
O35
Name in latin
Cura matris propter laesionem [suspectam] fetus ex abusu alcohol matris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 998 989 -
Only index persons 962 962 -
Unadjusted period prevalence (%)
Whole population 0.03 0.03 -
Only index persons 0.04 0.04 -
Median age at first event (years)
Whole population - 29.01 -
Only index persons - 28.94 -

-FinnGen-

Key figures

All Female Male
Number of individuals 115 115 -
Unadjusted period prevalence (%) 0.04 0.04 -
Median age at first event (years) 30.20 30.20 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
124
Matched controls
1240
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O35.4
ICD-10 Finland
Maternal care for (suspected) damage to fetus from alcohol
+∞
179.0
124
*
Z2446
NOMESCO Finland
Social worker
35.3
87.3
67
40
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
28.4
62.7
48
27
N07BB01
ATC
disulfiram; oral
36.4
59.2
40
16
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
639.6
46.5
43
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
15.8
34.9
34
29
Z2221
NOMESCO Finland
Medical doctor
9.3
31.0
93
303
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
9.5
29.5
44
68
B18.2
ICD-10 Finland
Chronic viral hepatitis C
68.0
27.7
31
6
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
10.8
27.0
34
42
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
13.1
26.3
28
27
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
6.8
25.7
64
168
F32.9
ICD-10 Finland
Depressive episode, unspecified
6.6
23.7
56
138
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
6.9
21.7
95
398
RS120, ,
NOMESCO Finland
+∞
21.5
20
*
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.7
21.5
26
30
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
5.8
21.1
61
178
Z3231
NOMESCO Finland
Registered nurse
5.7
20.9
65
202
P15
ICPC
Chronic alcohol abuse
44.2
20.8
25
7
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
125.2
20.2
21
*
F10.20
ICD-10 Finland
Alcohol dependence currently independent
55.9
20.0
23
5
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
9.2
18.5
25
33
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
23.1
18.3
26
14
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
8.4
17.7
26
38
N05BA04
ATC
oxazepam; oral
4.9
17.5
69
253
N05AH04
ATC
quetiapine; oral
4.9
17.2
62
211
N05BA01
ATC
diazepam; systemic, rectal
6.1
16.6
35
75
XF400
NOMESCO Finland
ECG with 12 standard connections
6.6
16.1
30
57
N06AX11
ATC
mirtazapine; oral
4.6
16.0
75
308
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
4.6
16.0
65
240
N06AB04
ATC
citalopram; systemic
4.7
15.3
49
150
N05BA12
ATC
alprazolam; oral
6.2
14.9
30
61
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
7.6
14.7
23
36
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
7.7
14.2
22
34
N05AH03
ATC
olanzapine; systemic
6.2
14.1
28
56
MAX99
NOMESCO Finland
Assistance to normal delivery
4.2
14.1
59
219
ZY010
NOMESCO Finland
Hospital outpatient
6.2
13.9
27
53
Z37.0
ICD-10 Finland
Single live birth
4.1
13.7
59
223
Z32.1
ICD-10 Finland
Pregnancy confirmed
4.1
13.3
59
227
T74.1
ICD-10 Finland
Physical abuse
14.6
13.2
22
18
P19
ICPC
Drug abuse
56.4
13.2
15
*
F10.25
ICD-10 Finland
Alcohol dependence continuous use
56.4
13.2
15
*
N05AX08
ATC
risperidone; systemic
6.3
13.1
25
48
P29
ICPC
Psychological sympt/compl other
5.0
13.0
34
87
LCH11
NOMESCO Finland
Pharmacologic abortion
5.0
13.0
34
87
D10
ICPC
Vomiting
5.4
13.0
30
69
N06AX16
ATC
venlafaxine; oral
4.4
12.9
44
139
ZXE00
NOMESCO Finland
One hour or less
4.0
12.7
82
404
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
6.6
12.4
22
39
D01
ICPC
Abdominal pain/cramps general
4.5
12.1
37
107
N03AG01
ATC
valproic acid; systemic, rectal
6.0
12.0
24
48
ZXD10
NOMESCO Finland
Scheduled procedure
3.7
12.0
68
304
F10.24
ICD-10 Finland
Alcohol depence active use
33.8
12.0
15
5
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
33.8
12.0
15
5
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
6.6
11.9
21
37
A97
ICPC
No disease
4.1
11.9
44
147
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
5.4
11.9
27
61
Z72.2
ICD-10 Finland
Drug use
71.9
11.8
13
*
F11.25
ICD-10 Finland
Relationship caused by opiates continuously used
71.9
11.8
13
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.8
11.8
76
368
R2110
NOMESCO Finland
Giving the first information
5.3
11.7
27
62
O98.4
ICD-10 Finland
Viral hepatitis complicating pregnancy, childbirth and the puerperium
131.7
11.6
12
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
9.8
11.4
23
28
Z3232
NOMESCO Finland
Midwife
3.7
11.3
52
201
EB1AA, ,
SPAT
5.4
11.3
25
55
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
10.0
11.1
22
26
S29
ICPC
Skin symptom/complaint other
4.1
11.1
39
125
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
14.8
11.1
18
14
X14
ICPC
Vaginal discharge
10.7
11.0
21
23
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
6.1
11.0
21
40
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
65.8
10.8
12
*
EBA05
NOMESCO Finland
Complicated extraction of tooth
3.7
10.7
46
169
SPAT1265
SPAT
Breathalyser
119.7
10.6
11
*
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
12.9
10.5
18
16
N05CF01
ATC
zopiclone; oral
3.5
10.4
52
210
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
43.9
10.2
12
*
Z72.1
ICD-10 Finland
Alcohol use
28.7
10.0
13
5
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
3.4
9.8
50
204
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.8
9.6
37
125
F11.22
ICD-10 Finland
Addiction-induced dependence is currently independent but uses substitute intermittent medication
32.9
9.6
12
*
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
8.9
9.6
20
26
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
107.9
9.6
10
*
RS122, ,
NOMESCO Finland
107.9
9.6
10
*
V03AA01, ,
ATC
+∞
9.5
9
*
RS312, ,
NOMESCO Finland
+∞
9.5
9
*
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
5.7
9.4
19
38
P01AB01
ATC
metronidazole; oral, rectal
3.3
9.4
78
422
U01
ICPC
Dysuria/painful urination
4.7
9.3
24
60
W14
ICPC
Contraception female other
4.0
9.3
32
100
N05AX12
ATC
aripiprazole; systemic
5.4
9.2
20
43
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.2
9.2
28
80
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
20.5
9.1
13
7
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
7.7
9.1
21
32
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
3.5
9.1
40
147
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
3.5
9.1
42
160
N06AX12
ATC
bupropion; oral
4.0
8.9
29
87
XMA22
NOMESCO Finland
General examination of pregnant woman
3.7
8.9
35
120
Z3226
NOMESCO Finland
Physiotherapist
3.7
8.7
34
116
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
12.0
8.6
15
14
RS121, ,
NOMESCO Finland
96.3
8.5
9
*
RS310, ,
NOMESCO Finland
96.3
8.5
9
*
N06AB03
ATC
fluoxetine; oral
3.9
8.4
29
90
B17.1
ICD-10 Finland
Acute hepatitis C
+∞
8.4
8
*
F31.8
ICD-10 Finland
Other bipolar affective disorders
10.0
8.3
16
18
F61.0
ICD-10 Finland
Mixed personality disorders
11.2
8.3
15
15
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.2
8.2
18
39
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.0
8.1
26
77
ZXD20
NOMESCO Finland
Day surgery
3.8
8.0
29
93
WX110, ,
SPAT
4.4
7.9
22
58
TQX20
NOMESCO Finland
Implantation of subcutaneous medicament implant
16.4
7.9
12
8
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
4.7
7.9
20
49
X23
ICPC
Fear sexually transm dis female
3.4
7.9
34
123
N03AX09
ATC
lamotrigine; oral
4.5
7.8
21
54
WX892
NOMESCO Finland
Monitored bed care
6.8
7.8
19
32
IGY02
NOMESCO Finland
Psychiatric monitoring contact
6.6
7.6
19
33
Z30.8
ICD-10 Finland
Other contraceptive management
4.7
7.6
19
46
N06AB10
ATC
escitalopram; oral
2.9
7.6
58
291
N05AF03
ATC
chlorprothixene; systemic
10.4
7.5
14
15
W01
ICPC
Question of pregnancy
10.4
7.5
14
15
O80.0
ICD-10 Finland
Spontaneous vertex delivery
3.0
7.5
88
552
RS210, ,
NOMESCO Finland
85.0
7.5
8
*
F15.1
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, harmful use
85.0
7.5
8
*
K08.3
ICD-10 Finland
Retained dental root
7.4
7.4
17
26
P74
ICPC
Anxiety disorder/anxiety state
4.2
7.4
22
61
RS311, ,
NOMESCO Finland
+∞
7.4
7
*
P76
ICPC
Depressive disorder
3.6
7.3
28
93
N06AB06
ATC
sertraline; oral
3.3
7.3
33
122
F10.09
ICD-10 Finland
Alcohol intoxication UNS
21.6
7.3
10
5
N05BA02
ATC
chlordiazepoxide; systemic
21.6
7.3
10
5
F13.22
ICD-10 Finland
Addiction relationship caused by sedatives and hypnotics currently independent but uses substitute intermittent medication
32.1
7.3
9
*
D12
ICPC
Constipation
13.1
7.2
12
10
K04.5
ICD-10 Finland
Chronic apical periodontitis
3.0
7.2
41
174
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
3.1
7.1
38
156
P16
ICPC
Acute alcohol abuse
11.9
7.0
12
11
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
11.9
7.0
12
11
N76.0
ICD-10 Finland
Acute vaginitis
3.3
6.9
30
108
F13.25
ICD-10 Finland
Addiction caused by sedative and hypnotic continuous use
42.4
6.8
8
*
F15.2
ICD-10 Finland
Mental and behavioural disorders due to use of other stimulants, including caffeine, dependence syndrome
42.4
6.8
8
*
EB1SA, ,
SPAT
4.6
6.8
17
41
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.1
6.8
20
55
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
24.0
6.8
9
*
EBA30
NOMESCO Finland
Extraction of root of tooth
9.5
6.7
13
15
IGY99
NOMESCO Finland
Other psychiatric treatment contact
6.9
6.7
16
26
P17
ICPC
Tobacco abuse
13.3
6.7
11
9
SPAT1324
SPAT
Screening procedure
0.2
6.7
5
264
L12
ICPC
Hand/finger symptom/complaint
3.1
6.7
34
135
R05
ICPC
Cough
2.8
6.6
49
238
WX110
NOMESCO Finland
Infiltration anesthesia
4.1
6.6
110
812
D06
ICPC
Abdominal pain localized other
3.6
6.6
24
77
W79
ICPC
Unwanted pregnancy
6.6
6.6
16
27
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.7
6.5
23
72
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
15.4
6.5
10
7
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
15.4
6.5
10
7
F60.2
ICD-10 Finland
Dissocial personality disorder
73.5
6.5
7
*
Z71.8
ICD-10 Finland
Other specified counselling
2.6
6.5
64
359
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
10.1
6.4
12
13
N05CD07
ATC
temazepam; oral
6.4
6.4
16
28
F11.29
ICD-10 Finland
Addiction caused by opiates UNS
28.3
6.3
8
*
R1240
NOMESCO Finland
Social assessment of need and possibilities of rehabilitation
28.3
6.3
8
*
Z30.0
ICD-10 Finland
General counselling and advice on contraception
3.2
6.3
29
108
Z10.1
ICD-10 Finland
Routine general health check-up of inhabitants of institutions
+∞
6.3
6
*
ICC03
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric ward
+∞
6.3
6
*
B86
ICD-10 Finland
Scabies
7.4
6.2
14
21
R02
ICPC
Shortness of breath/dyspnoea
3.7
6.2
22
69
A46
ICD-10 Finland
Erysipelas
4.3
6.2
17
44
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
9.4
6.2
12
14
D25
ICPC
Abdominal distension
13.5
6.2
10
8
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.6
6.1
59
325
F39
ICD-10 Finland
Unspecified mood [affective] disorder
7.9
6.1
13
18
P01
ICPC
Feeling anxious/nervous/tense
2.7
6.1
44
210
U02
ICPC
Urinary frequency/urgency
3.2
6.1
28
104

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
38
53
9.90
27.57
3.6
1.5
—
—
—
0
0
43
71
8.74
27.11
6.6
1.9
—
—
—
0
0
42
92
6.39
19.76
4.4
1.5
—
—
—
0
0
43
99
6.12
19.15
4.3
1.5
—
—
—
0
0
43
99
6.12
19.15
4.5
1.5
—
—
—
0
0
43
100
6.05
18.92
4.2
1.5
—
—
—
0
0
42
99
5.90
18.15
4.4
1.5
—
—
—
0
0
39
89
5.93
17.39
3.1
2.4
37.23
28.74
u/l
0.45
31
78
37
84
5.85
16.53
4.1
1.5
—
—
—
0
0
41
121
4.57
13.21
1.7
1.4
—
—
—
0
0
87
450
4.13
12.43
5.7
4.8
12.40
9.13
umol/l
1.02
82
422
56
220
3.82
12.00
3.0
2.4
0.22
0.40
e6/l
0.48
46
156
56
228
3.66
11.24
2.9
2.4
—
—
—
0
0
20
38
6.08
10.51
7.5
7.8
—
—
—
0
0
36
114
4.04
10.33
2.6
2.1
5.53
4.50
e6/l
0.18
17
54
53
220
3.46
10.14
4.5
2.9
6.35
8.13
mmol/l
2.14
48
197
67
326
3.30
9.81
4.1
3.0
42.48
55.45
e6/l
0.18
45
200
21
30
8.20
9.52
1.8
1.2
—
—
—
0
0
33
104
3.96
9.47
1.8
2.2
10.56
5.34
umol/l
0.43
28
86
56
250
3.26
9.39
5.8
5.8
—
—
—
0
0
56
255
3.18
9.01
3.0
2.4
15.28
69.70
e6/l
1.36
46
190
15
13
12.93
8.84
1.7
1.2
—
—
—
0
0
41
159
3.36
8.55
2.0
2.2
513.33
572.24
mosm/kgh2o
0.61
30
131
33
112
3.65
8.45
1.8
1.9
—
—
—
0
0
39
150
3.33
8.21
5.4
4.0
—
—
—
0
0
49
216
3.10
8.21
2.3
1.5
—
—
—
0
0
82
481
3.08
8.18
2.9
2.1
—
—
—
0
0
71
397
2.84
7.53
2.2
1.7
—
—
—
0
0
41
173
3.05
7.30
2.0
2.2
13.60
14.07
e6/l
0.03
33
149
28
94
3.56
7.21
1.7
1.3
—
—
—
0
0
10
6
17.95
6.87
1.3
1.0
—
—
—
0
0
15
23
7.26
6.57
1.3
1.5
—
—
—
0
0
99
710
2.96
5.77
7.1
6.2
83.54
70.19
u/l
1.34
91
665
17
49
3.86
5.39
4.5
2.6
—
—
—
0
0
28
116
2.83
5.00
1.4
1.4
—
—
—
0
0
27
113
2.78
4.72
1.3
1.4
—
—
—
0
0
27
113
2.78
4.72
1.3
1.4
—
—
—
0
0
42
221
2.36
4.57
3.8
3.0
—
—
—
0
0
50
287
2.24
4.42
3.5
2.1
—
—
—
0
0
9
13
7.37
4.24
1.6
1.5
—
—
—
0
0
21
437
0.37
4.23
1.5
2.0
—
—
—
0
0
27
120
2.60
4.18
2.9
2.4
48.42
289.67
ng/l
0.49
12
43
74
506
2.15
4.12
5.6
3.6
6.60
6.05
mmol/l
0.51
68
437
53
322
2.13
3.99
1.6
1.7
96.63
98.16
pmol/l
0.08
18
183
16
55
3.19
3.90
15.1
6.7
105.63
105.36
mmol/l
0.09
16
55
6
5
12.51
3.80
1.3
1.0
71.17
70.40
%
—
6
5
9
250
0.31
3.75
1.4
1.6
—
—
—
0
0
44
254
2.14
3.74
7.2
6.2
1.05
1.04
inr
—
10
101
11
26
4.54
3.60
1.2
1.0
—
—
—
0
0
82
610
2.02
3.34
11.0
7.8
4.18
3.96
e9/l
0.42
64
539
78
571
1.99
3.31
2.6
2.4
—
—
—
0
0
12
34
3.79
3.30
1.8
3.9
24.32
25.01
mmol/l
0.27
12
34
66
459
1.94
3.24
6.2
7.2
0.00
0.00
e9/l
0.50
48
370
90
696
2.07
3.23
6.4
3.9
—
28.40
—
0
10
10
25
4.26
3.16
1.2
1.0
—
—
—
0
0
114
979
3.04
3.07
15.7
8.2
138.79
139.53
mmol/l
3.42
109
946
114
980
3.02
3.05
14.9
8.2
3.87
3.88
mmol/l
0.15
109
941
12
40
3.21
2.78
1.5
1.8
—
—
—
0
0
21
100
2.32
2.78
1.4
1.6
1306.17
1055.71
nmol/l
0.39
12
79
17
329
0.44
2.60
2.7
2.5
—
—
—
0
0
46
306
1.80
2.44
1.8
2.0
—
—
—
0
0
20
99
2.22
2.42
1.3
1.2
—
—
—
0
0
8
22
3.81
2.41
21.4
12.2
0.73
0.67
%
—
8
22
8
22
3.81
2.41
7.9
2.0
0.66
0.67
%
—
8
22
8
22
3.81
2.41
21.4
12.2
1.01
0.85
%
—
8
22
8
23
3.64
2.31
21.4
11.9
95.76
95.76
%
—
8
23
8
23
3.64
2.31
1.8
2.2
—
—
—
0
0
6
13
4.79
2.30
1.7
1.2
—
—
—
0
0
7
18
4.06
2.29
4.3
2.3
13.14
16.70
u/ml
—
7
18
14
279
0.44
2.27
4.6
3.1
0.00
0.01
estimate
—
6
116
8
24
3.49
2.22
7.9
1.9
2.30
1.35
%
—
8
24
114
1016
2.51
2.15
4.6
5.0
1.68
1.63
mu/l
0.21
103
970
8
27
3.09
1.97
7.9
2.6
134.88
128.78
g/l
—
8
27
50
358
1.66
1.97
1.8
1.7
—
—
—
0
0
7
22
3.31
1.91
1.1
1.4
—
—
—
0
0
19
102
2.02
1.89
2.1
1.5
—
—
—
0
0
5
12
4.29
1.84
18.0
17.3
1429.80
1981.75
nmol/l
—
5
12
8
29
2.88
1.82
1.0
1.4
—
—
—
0
0
68
537
1.59
1.75
5.5
5.0
0.54
0.52
e9/l
0.44
54
479
70
558
1.58
1.72
5.5
5.4
0.17
0.18
e9/l
0.26
57
509
68
539
1.58
1.71
5.5
5.0
0.04
0.04
e9/l
0.09
55
478
54
406
1.58
1.70
1.7
1.8
—
—
—
0
0
106
941
1.87
1.67
3.8
3.0
6.00
5.55
mmol/l
1.38
95
888
38
267
1.61
1.57
2.8
2.2
48.66
54.05
u/l
0.50
32
252
9
178
0.47
1.55
1.3
1.2
—
—
—
0
0
88
750
1.60
1.54
5.7
3.9
—
—
—
0
0
115
1066
2.08
1.43
15.5
9.7
28.45
17.85
mg/l
1.69
92
793
35
249
1.57
1.36
1.9
1.7
0.77
0.71
mg/l
0.07
23
181
17
100
1.81
1.31
1.4
1.4
378.88
260.70
mu/l
0.46
17
89
68
562
1.46
1.27
5.6
5.0
2.12
1.99
e9/l
0.75
57
515
5
19
2.70
1.23
1.2
1.4
—
—
—
0
0
0
35
0.00
1.17
0.0
1.2
—
—
—
0
0
119
1131
2.29
1.06
11.5
9.0
—
—
—
0
0
9
46
2.03
1.06
1.6
1.7
—
—
—
0
0
12
68
1.85
1.04
1.0
1.2
—
—
—
0
0
98
886
1.51
1.04
3.3
4.4
13.30
14.19
pmol/l
4.24
89
838
19
125
1.61
1.01
1.2
1.2
—
—
—
0
0
38
292
1.43
1.00
1.2
1.4
2.94
2.01
g/l
1.42
17
198
0
29
0.00
0.99
0.0
1.0
—
0.60
—
0
13
10
57
1.82
0.86
1.1
1.4
—
—
—
0
0
6
32
1.92
0.83
1.0
1.3
—
—
—
0
0
0
25
0.00
0.80
0.0
1.2
—
30.60
—
0
20
6
107
0.54
0.76
3.7
3.0
—
—
—
0
0
5
24
2.13
0.75
2.4
3.0
—
—
—
0
0
7
38
1.89
0.75
1.0
1.1
—
—
—
0
0
10
61
1.70
0.71
1.1
1.3
—
—
—
0
0
0
20
0.00
0.61
0.0
1.2
—
—
—
0
0
9
132
0.66
0.55
1.7
1.7
—
—
—
0
0
6
97
0.60
0.54
1.0
1.1
—
—
—
0
0
6
39
1.57
0.54
1.8
3.7
—
7.40
—
0
5
6
40
1.52
0.52
1.0
1.1
—
—
—
0
0
87
808
1.26
0.51
4.5
3.6
35.53
36.87
mmol/mol
0.66
80
777
57
507
1.23
0.50
4.8
5.7
—
—
—
0
0
51
454
1.21
0.43
2.0
1.9
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
—
—
0
0
0
15
0.00
0.41
0.0
1.7
—
135.80
—
0
10
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
19
232
0.79
0.38
1.4
1.3
12.60
23.43
iu/ml
—
6
70
17
138
1.27
0.32
1.4
1.3
24.22
22.75
iu/l
—
10
124
7
98
0.70
0.32
2.0
2.2
—
19.11
—
0
9
7
53
1.34
0.31
5.9
2.8
—
—
—
0
0
15
121
1.27
0.30
1.2
1.2
—
—
—
0
0
9
77
1.18
0.25
1.1
1.1
—
—
—
0
0
28
249
1.16
0.23
1.8
1.9
1.97
2.55
mg/l
0.90
23
216
5
41
1.23
0.22
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
38.72
—
0
10
0
10
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
0
12
0.00
0.21
0.0
5.8
—
111.46
—
0
5
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
56
528
1.11
0.19
3.8
2.9
0.00
0.00
estimate
—
6
122
18
159
1.15
0.16
3.5
4.0
6.58
17.23
mg/mmol
0.82
11
105
14
121
1.18
0.16
1.1
1.1
—
—
—
0
0
12
102
1.20
0.16
1.4
1.2
—
—
—
0
0
16
180
0.87
0.14
2.3
2.2
130.18
65.79
ug/g
0.36
11
137
13
148
0.86
0.13
2.5
2.2
6773.11
6487.93
u/l
—
7
63
55
528
1.07
0.11
3.9
3.0
0.00
0.00
estimate
—
6
112
99
973
1.09
0.09
3.3
3.1
2.86
2.85
mmol/l
0.03
92
929
6
57
1.06
0.08
3.8
2.4
—
—
—
0
0
95
966
0.93
0.08
2.9
3.0
1.47
1.52
mmol/l
0.53
86
926
17
157
1.10
0.07
3.2
3.4
41.93
121.21
mg/l
—
10
105
7
84
0.82
0.07
1.0
1.3
77.46
398.64
u/ml
—
7
77
18
168
1.08
0.06
1.8
2.8
—
—
—
0
0
25
239
1.06
0.04
2.1
2.6
24.96
11.95
ng/l
—
10
76
10
109
0.91
0.04
2.1
1.8
416.30
385.43
nmol/l
—
10
104
96
970
0.95
0.03
2.9
3.0
4.65
4.75
mmol/l
0.58
89
928
53
523
1.02
0.01
6.3
4.2
0.00
0.01
estimate
—
5
117
92
919
1.00
0.00
2.5
2.7
1.23
1.16
mmol/l
0.41
82
873
19
187
1.02
0.00
1.7
2.3
—
—
—
0
0
10
102
0.98
0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
1.96
—
0
9
0
9
0.00
-0.00
0.0
2.8
—
1.04
—
0
9
8
81
0.99
-0.00
1.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.7
—
8.29
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
2110.00
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
506.60
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
25.33
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
91.83
—
0
6
0
7
0.00
-0.00
0.0
2.6
—
104.86
—
0
7
0
9
0.00
-0.00
0.0
2.8
—
6.37
—
0
9
0
8
0.00
-0.00
0.0
2.8
—
72.75
—
0
8
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
1.38
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
0.85
—
0
5
0
7
0.00
-0.00
0.0
2.6
—
3.77
—
0
7
0
5
0.00
-0.00
0.0
2.0
—
1.56
—
0
5
0
9
0.00
-0.00
0.0
1.7
—
950.56
—
0
9
0
6
0.00
-0.00
0.0
2.3
—
0.26
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
14.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
43.86
—
0
9
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
6
63
0.95
-0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
28.00
—
0
5

Mortality – FinRegistry

Association

Association between endpoint MATERNCAREFETUSALCO and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have MATERNCAREFETUSALCO.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: MATERNCAREFETUSALCO – Maternal care for (suspected) damage to fetus from alcohol

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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