No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2836 |
4. Check minimum number of eventsNone |
2836 |
5. Include endpointsNone |
2836 |
6. Filter based on genotype QC (FinnGen only) |
2836 |
Control definitions (FinnGen only)
- Control exclude
- I9_OTHHEART
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Left bundle-branch block
based on the number of shared cases.
Similar with more cases:
- Conduction disorders
- Other heart diseases
- Other heart diseases, wide
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 17107 | 8747 | 8259 |
| Only index persons | 14924 | 7794 | 7130 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.24 | 0.25 | 0.23 |
| Only index persons | 0.28 | 0.29 | 0.27 |
| Median age at first event (years) | |||
| Whole population | 69.91 | 70.38 | 69.35 |
| Only index persons | 69.06 | 69.43 | 68.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2836 | 1414 | 1422 |
| Unadjusted period prevalence (%) | 0.55 | 0.48 | 0.63 |
| Median age at first event (years) | 68.17 | 66.91 | 69.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2492
- Matched controls
- 24918
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
15.0
323.0
1248
1565
I48
ICD-10 Finland
Atrial fibrillation and flutter
101.5
323.0
739
103
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
430.6
323.0
453
13
207
Kela drug reimbursment
Chronic arrhythmias
160.8
323.0
481
37
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
323.0
406
*
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
434.2
323.0
456
13
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
7.3
323.0
1069
2310
I50.1
ICD-10 Finland
Left ventricular failure
1513.2
323.0
488
*
I42.0
ICD-10 Finland
Dilated cardiomyopathy
5045.8
323.0
432
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
298.7
323.0
593
26
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
6096.4
323.0
2057
18
I50.9
ICD-10 Finland
Heart failure, unspecified
111.8
323.0
758
97
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
8.4
323.0
830
1392
I50.0
ICD-10 Finland
Congestive heart failure
201.9
323.0
348
20
C07AB07
ATC
bisoprolol; oral
5.8
323.0
1659
6400
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
413.6
299.4
295
8
201
Kela drug reimbursment
Chronic cardiac insufficiency
31.9
276.9
372
136
I44.4
ICD-10 Finland
Left anterior fascicular block
1467.3
275.0
263
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
11.7
249.4
491
510
C03CA01
ATC
furosemide; systemic
4.8
248.5
1071
3360
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
833.7
235.4
228
*
C03DA01
ATC
spironolactone; oral
8.8
232.0
544
770
XF404
NOMESCO Finland
Ambulatory ECG
12.6
224.8
424
398
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
2144.3
217.8
208
*
B01AA03
ATC
warfarin; systemic
6.5
201.7
590
1137
TFP20
NOMESCO Finland
Cardiodefibrillation
151.9
198.8
209
15
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
92.2
190.7
211
25
I44.2
ICD-10 Finland
Atrioventricular block, complete
+∞
189.0
179
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
47.9
185.4
227
52
C09AA05
ATC
ramipril; oral
3.6
162.3
950
3614
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
122.2
159.3
171
15
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
121.5
158.3
170
15
B01AF02
ATC
apixaban; oral
13.4
156.1
283
236
I44.6
ICD-10 Finland
Other and unspecified fascicular block
1590.9
152.7
147
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
20.9
151.0
229
120
C01AA05
ATC
digoxin; systemic
15.9
150.5
253
176
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
145.5
1318
6743
I44.0
ICD-10 Finland
Atrioventricular block, first degree
118.7
144.9
156
14
AN1
HP
Coronary angiography
5.0
138.8
498
1177
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.5
134.0
783
2887
I49.5
ICD-10 Finland
Sick sinus syndrome
344.7
131.8
132
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
123.5
130.5
140
12
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.2
120.8
816
3306
I50
ICD-10 Finland
Heart failure
29.0
115.4
158
58
XF640
NOMESCO Finland
NA
18.1
114.0
181
107
R06.0
ICD-10 Finland
Dyspnoea
3.1
113.3
772
3120
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
6.8
112.6
302
492
K78
ICPC
Atrial fibrillation/flutter
16.5
111.2
183
119
R07.4
ICD-10 Finland
Chest pain, unspecified
2.9
109.2
855
3775
C01BD01
ATC
amiodarone; systemic
167.3
107.1
112
7
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
1072.1
106.1
103
*
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
9.6
105.9
226
256
GD1LA
NOMESCO Finland
GD
184.3
102.1
106
6
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
+∞
101.7
97
*
I47.2
ICD-10 Finland
Ventricular tachycardia
268.6
101.5
103
*
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
99.6
95
*
I44.1
ICD-10 Finland
Atrioventricular block, second degree
263.0
99.4
101
*
I48.2
ICD-10 Finland
Chronic atrial fibrillation
+∞
95.4
91
*
TFP34
NOMESCO Finland
Electrophysiological investigation
867.0
86.1
84
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
437.0
85.6
85
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
32.8
83.2
110
35
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
219.7
82.8
85
*
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
81.7
78
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
81.1
454
1540
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
77.9
79.7
90
12
C09DX04
ATC
valsartan and sacubitril; oral
+∞
79.6
76
*
XF402
NOMESCO Finland
ECG with work load test
3.8
77.8
362
1057
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
57.6
75.4
89
16
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
749.7
74.6
73
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
+∞
72.2
69
*
C01DA14
ATC
isosorbide mononitrate; oral
2.9
72.1
506
2000
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
89.4
70.3
78
9
AS4
HP
Physiological pacemaker insertion DDD (R)
+∞
70.1
67
*
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
243.3
69.6
71
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.4
68.1
188
313
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
335.6
65.8
66
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.7
62.1
485
2029
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
61.9
1588
11517
FPE37
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
+∞
57.5
55
*
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
+∞
56.5
54
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
3.2
56.1
322
1094
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
52.1
55.2
66
13
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.8
54.7
193
428
FPE25
NOMESCO Finland
Implantation of biventricular cardiac pacemaker, atrial and ventricular electrodes, CRT-P (DDDR)
+∞
53.3
51
*
C10AA05
ATC
atorvastatin; oral
2.0
52.9
1065
6863
I34.1
ICD-10 Finland
Mitral (valve) prolapse
62.4
52.5
61
10
4263A
ICD-9 Finland
Conduction disorders, Other left bundle branch block
+∞
52.3
50
*
I45.3
ICD-10 Finland
Trifascicular block
518.1
51.6
51
*
K77
ICPC
Heart failure
18.5
50.8
79
44
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.3
48.7
528
2595
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
106.1
47.9
52
5
WX892
NOMESCO Finland
Monitored bed care
3.8
47.3
213
595
R55
ICD-10 Finland
Syncope and collapse
2.8
45.6
330
1299
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
+∞
44.9
43
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
445.2
44.3
44
*
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
43.9
42
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
+∞
43.9
42
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
9.1
43.7
94
107
I25.2
ICD-10 Finland
Old myocardial infarction
3.5
43.0
212
638
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.1
41.5
574
3123
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.9
40.5
178
486
I49.1
ICD-10 Finland
Atrial premature depolarization
11.5
38.7
73
65
I44.5
ICD-10 Finland
Left posterior fascicular block
+∞
38.6
37
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
38.0
409
1981
81
HP
Angiography of the heart and coronary arteries
3.4
38.0
200
632
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
5.0
37.8
127
267
M04AA01
ATC
allopurinol; systemic
2.4
37.7
348
1562
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
+∞
37.6
36
*
ZXE00
NOMESCO Finland
One hour or less
1.8
36.8
926
6209
ZXD05
NOMESCO Finland
Urgent procedure
1.9
36.8
700
4273
I45.2
ICD-10 Finland
Bifascicular block
131.9
36.8
39
*
FN1AD
NOMESCO Finland
CT of coronary arteries
10.4
36.3
72
71
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
36.2
197
638
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.2
36.0
199
652
C07AB02
ATC
metoprolol; systemic
2.0
35.7
525
2907
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
+∞
35.5
34
*
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
+∞
35.5
34
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.5
35.0
107
202
Z2221
NOMESCO Finland
Medical doctor
1.9
34.9
662
4028
N02BE01
ATC
paracetamol; systemic, rectal
1.9
34.2
2048
17683
AP1
HP
Catheterization of the left side of the heart
8.3
33.8
76
94
K80
ICPC
Cardiac arrhythmia NOS
3.6
33.7
162
476
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
7.3
33.6
82
115
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
5.6
33.5
101
188
I44.3
ICD-10 Finland
Other and unspecified atrioventricular block
+∞
33.4
32
*
R00.1
ICD-10 Finland
Bradycardia, unspecified
6.6
33.2
87
135
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
31.2
32.6
43
14
A02BC02
ATC
pantoprazole; systemic
1.7
32.4
1536
12225
C07AA07
ATC
sotalol; systemic
5.9
32.2
92
160
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
31.9
591
3546
I45.0
ICD-10 Finland
Right fascicular block
34.7
31.9
41
12
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
114.8
31.7
34
*
J01DB01
ATC
cefalexin; oral
1.7
31.6
1859
15669
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
4.2
31.2
124
309
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
30.3
29
*
FPJ24
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
+∞
30.3
29
*
H02AB06
ATC
prednisolone; systemic
1.6
30.0
1087
7966
AQ1
HP
Conventional electrophysiological examination
305.8
29.9
30
*
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
+∞
29.2
28
*
R53
ICD-10 Finland
Malaise and fatigue
1.9
29.2
462
2607
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
3.6
29.0
136
392
B01AC04
ATC
clopidogrel; oral
2.0
28.9
424
2322
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.7
28.9
214
847
R03AC02
ATC
salbutamol; inhalant
1.6
28.8
1137
8494
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
11.0
28.8
55
51
C01BC04
ATC
flecainide; systemic
29.6
28.5
38
13
I42
ICD-10 Finland
Cardiomyopathy
+∞
28.2
27
*
I20.09
ICD-10 Finland
Unstable angina
3.2
28.1
158
521
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.3
27.8
272
1245
B01AF01
ATC
rivaroxaban; oral
2.3
27.6
266
1210
J01CA04
ATC
amoxicillin; systemic
1.6
27.6
1768
14896
ASB
HP
Insertion of a biventricular physiological pacemaker DDD (R)
+∞
27.1
26
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
6.9
26.9
68
101
I45.9
ICD-10 Finland
Conduction disorder, unspecified
76.0
26.8
30
*
R00.2
ICD-10 Finland
Palpitations
3.2
26.8
146
473
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
273.8
26.8
27
*
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
141.5
26.7
28
*
C10AA01
ATC
simvastatin; oral
1.6
26.6
1142
8655
I45.1
ICD-10 Finland
Other and unspecified right bundle-branch block
52.2
26.2
31
6
TFP35
NOMESCO Finland
Electroanatomical mapping
+∞
26.1
25
*
WX872
NOMESCO Finland
Intensive care
3.7
25.7
115
319
XF409
NOMESCO Finland
Other special ECG
44.8
25.5
31
7
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
25.2
194
784
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
+∞
25.0
24
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
25.0
736
5032
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
3.0
24.8
152
531
K84
ICPC
Heart disease other
5.3
24.8
77
149
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
70.6
24.8
28
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
24.6
198
820
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
24.6
461
2747
R02
ICPC
Shortness of breath/dyspnoea
2.2
24.5
272
1322
M10.9
ICD-10 Finland
Gout, unspecified
2.8
24.5
166
622
K83
ICPC
Heart valve disease NOS
29.4
24.1
32
11
AB2
HP
AVR bio, stent
+∞
24.0
23
*
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
+∞
24.0
23
*
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
+∞
24.0
23
*
R07.3
ICD-10 Finland
Other chest pain
2.3
23.7
228
1034
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
242.1
23.7
24
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
23.6
561
3598
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
6.4
23.4
62
99
I20.00
ICD-10 Finland
Unstable angina
4.1
23.1
93
236
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
+∞
22.9
22
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
+∞
22.9
22
*
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
+∞
22.9
22
*
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.9
22.7
145
522
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
6.2
22.4
61
101
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
15.8
22.3
36
23
B01AE07
ATC
dabigatran etexilate; oral
4.7
22.3
76
164
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
21.9
630
4249
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
+∞
21.9
21
*
AS6
HP
Biventricular physiological heart failure pacemaker insertion DDD (R)
+∞
21.9
21
*
G47.3
ICD-10 Finland
Sleep apnoea
1.8
21.9
447
2726
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
21.7
238
1147
I11
ICD-10 Finland
Hypertensive heart disease
20.2
21.7
32
16
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
21.3
885
6541
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
21.0
832
6075
M10
ICD-10 Finland
Gout
3.1
21.0
117
386
FPE24
NOMESCO Finland
Implantation of biventricular cardiac pacemaker, ventricular electrodes, CRT-P (VVIR)
+∞
20.9
20
*
AP4
HP
Myocardial biopsy
+∞
20.9
20
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
20.9
1040
8006
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
77.4
20.7
23
*
C07AG02
ATC
carvedilol; oral
2.5
20.6
163
667
B01AF03
ATC
edoxaban; oral
17.0
20.5
32
19
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
20.4
646
4461
SPAT1263
SPAT
Sampling
1.5
20.2
900
6742
A10BK01
ATC
dapagliflozin; oral
3.0
20.1
118
404
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
19.8
225
1100
250
Kela drug reimbursment
NA
+∞
19.8
19
*
73
HP
Initial pacemaker installation
+∞
19.8
19
*
C08CA01
ATC
amlodipine; oral
1.5
19.4
844
6272
SPAT1097
SPAT
Recording of ECG
1.8
19.3
336
1938
WX110
NOMESCO Finland
Local anesthesy
1.5
19.1
1426
11865
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
19.1
483
3127
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
18.9
120
432
AA1AD
NOMESCO Finland
CT of head and brain
1.6
18.9
523
3472
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.8
18.9
379
2290
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
+∞
18.8
18
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
18.6
509
3366
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
18.4
373
2260
PD5AD
NOMESCO Finland
CT of aorta
6.4
18.4
48
76
J01MA12
ATC
levofloxacin; systemic
1.7
18.3
426
2691
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.5
18.2
142
578
C09CA03
ATC
valsartan; oral
2.1
18.2
222
1119
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.7
18.1
80
222
S18
ICPC
Laceration/cut
1.5
17.9
941
7253
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
17.9
117
428
M79.6
ICD-10 Finland
Pain in limb
1.5
17.8
754
5541
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
17.8
273
1505
42798
ICD-8 Finland
Symptomatic heart disease, Alia arrhytmia definita
+∞
17.7
17
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
+∞
17.7
17
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
17.6
335
1991
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
7.8
17.6
40
52
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
181.1
17.5
18
*
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.8
17.5
116
430
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
18.7
17.3
26
14
K99
ICPC
Cardiovascular disease other
4.6
17.3
60
133
71
HP
Electrophysiological Special Examination
42.3
17.3
21
5
C09AA02
ATC
enalapril; systemic
1.6
17.1
485
3233
R42
ICD-10 Finland
Dizziness and giddiness
1.6
17.1
485
3233
1CX08
NOMESCO Finland
NA
50.3
17.0
20
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
16.8
439
2859
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
16.7
806
6077
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
16.7
253
1387
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.0
16.6
96
326
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
90.6
16.6
18
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.5
16.5
132
545
FN1CB
NOMESCO Finland
Coronary flow reserve measurement with pressure wire
4.5
16.5
58
131
WX722
NOMESCO Finland
PEEP
2.8
16.1
107
396
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
16.0
269
1529
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
16.0
356
2215
C09AA04
ATC
perindopril; oral
2.4
15.9
134
569
WX002
NOMESCO Finland
Sedation and analgesia
1.6
15.8
445
2952
I51.4
ICD-10 Finland
Myocarditis, unspecified
+∞
15.6
15
*
FPJ00
NOMESCO Finland
Revision of pacemaker pulse generator or electrode
+∞
15.6
15
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
+∞
15.6
15
*
R05
ICD-10 Finland
Cough
1.6
15.6
422
2771
C08DA01
ATC
verapamil; systemic
3.3
15.1
76
235
FM3CN
NOMESCO Finland
Heart perfusion isotope imaging both at rest and with exercise
23.5
15.1
21
9
Z3231
NOMESCO Finland
Registered nurse
1.5
15.0
590
4239
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
6.3
14.8
39
63
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.6
14.7
110
438
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
14.6
14
*
R04.0
ICD-10 Finland
Epistaxis
2.2
14.5
147
685
AS2
HP
Ventricular pacemaker insertion VVI (R)
150.8
14.5
15
*
I48.4
ICD-10 Finland
Atypical atrial flutter
150.8
14.5
15
*
C03AA03
ATC
hydrochlorothiazide; oral
1.9
14.4
231
1294
R4110
NOMESCO Finland
Physiotherapy
1.5
14.2
572
4122
C10AA07
ATC
rosuvastatin; oral
1.5
14.2
557
3991
Q23.11
ICD-10 Finland
Bicuspid aortic valve
30.2
13.9
18
6
C08CA13
ATC
lercanidipine; oral
1.7
13.9
293
1790
C09CA06
ATC
candesartan; oral
1.6
13.8
452
3104
AP2
HP
Catheterization of the right side of the heart
53.6
13.8
16
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
13.8
933
7442
A46
ICD-10 Finland
Erysipelas
1.7
13.8
284
1722
R03BB04
ATC
tiotropium bromide; inhalant
1.8
13.7
236
1351
L28
ICPC
Limited function/disability (L)
1.6
13.7
363
2367
N19
ICD-10 Finland
Unspecified kidney failure
2.9
13.6
80
277
FXZ00
NOMESCO Finland
Off-pump cardiac operation
12.1
13.6
24
20
74
HP
Initial installation of the atrial pacemaker
+∞
13.5
13
*
FK1BT
NOMESCO Finland
Implantation of cardiac pacemaker with X-ray guidance
+∞
13.5
13
*
A98
ICPC
Health maint/preventive medicine
1.6
13.5
2191
20448
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
13.5
769
5937
FM1JR
NOMESCO Finland
Heart, extensive metabolic PET with CT
140.7
13.5
14
*
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
13.3
126
570
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.0
13.0
173
904
M10.0
ICD-10 Finland
Idiopathic gout
2.9
12.9
77
269
T90
ICPC
Diabetes non-insulin dependent
1.5
12.8
508
3642
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
12.7
217
1240
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
12.7
552
4031
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
12.6
294
1845
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
12.6
212
1204
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
12.5
706
5427
UJF32
NOMESCO Finland
Coloscopy
1.5
12.4
557
4089
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
12.4
674
5140
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
12.3
794
6248
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
12.3
187
1026
C09CA01
ATC
losartan; oral
1.5
12.2
533
3892
SPAT1325
SPAT
Vaccination
1.4
12.1
780
6127
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
2.3
12.1
112
500
SPAT1104
SPAT
Monitoring of emergency patient
2.1
12.1
134
650
J01DA01
ATC
[U] cefalexin; systemic
1.4
12.0
1325
11373
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
12.0
515
3747
M54.5
ICD-10 Finland
Low back pain
1.4
11.9
626
4735
J01FF01
ATC
clindamycin; systemic
1.5
11.8
527
3865
205
Kela drug reimbursment
Chronic hypertension
1.4
11.7
660
5058
J01AA02
ATC
doxycycline; systemic
1.4
11.7
1746
15696
B01AB05
ATC
enoxaparin; parenteral
1.4
11.7
629
4777
SPAT1254
SPAT
Administration of medicine
1.6
11.7
293
1877
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
11.7
285
1815
FM1DE
SPAT
NA
30.1
11.6
15
5
A10BA02
ATC
metformin; oral
1.4
11.6
609
4605
SPAT1262
SPAT
Handing over of treatment supplies
1.5
11.6
396
2740
H02AB07
ATC
prednisone; oral
1.6
11.5
312
2044
TFP40
NOMESCO Finland
Ablation treatment for a-v node re-entry activation
+∞
11.5
11
*
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
+∞
11.5
11
*
I41.8
ICD-10 Finland
Myocarditis in other diseases classified elsewhere
+∞
11.5
11
*
I48.3
ICD-10 Finland
Typical atrial flutter
+∞
11.5
11
*
AS8
HP
Physiological arrhythmia pacemaker insertionDDD (R) S
+∞
11.5
11
*
C10AX09
ATC
ezetimibe; oral
1.7
11.4
231
1396
J20
ICD-10 Finland
Acute bronchitis
1.8
11.4
198
1139
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
11.3
93
394
SPAT1153
SPAT
Removal of sutures
1.4
11.2
707
5521
R06.2
ICD-10 Finland
Wheezing
2.5
11.2
89
369
WZA90
NOMESCO Finland
Other doctors statement
1.5
11.2
426
3017
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
11.2
389
2703
K02.1
ICD-10 Finland
Caries of dentine
1.3
11.1
1032
8581
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
11.1
388
2698
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.2
11.0
112
523
A12BA01
ATC
potassium chloride; oral
2.4
11.0
96
416
K05
ICPC
Irregular heartbeat other
3.6
11.0
48
135
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
2.9
11.0
66
234
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.3
11.0
104
471
L17
ICPC
Foot/toe symptom/complaint
1.4
10.9
515
3808
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.9
346
2351
FM1TQ
NOMESCO Finland
Heart perfusion SPECT with low dose CT at rest and with exercise
15.5
10.8
17
11
XG466
NOMESCO Finland
Sleep oxymetry
2.7
10.8
70
260
R2110
NOMESCO Finland
Giving the first information
2.1
10.8
125
620
C01BA03
ATC
disopyramide; systemic
17.9
10.7
16
9
H25.8
ICD-10 Finland
Other senile cataract
1.6
10.7
281
1820
A11
ICPC
Chest pain NOS
1.9
10.7
153
822
I40.9
ICD-10 Finland
Acute myocarditis, unspecified
60.2
10.6
12
*
I44
ICD-10 Finland
Atrioventricular and left bundle-branch block
60.2
10.6
12
*
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
10.4
570
4328
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.6
10.4
74
289
FM1AT
NOMESCO Finland
Percutaneous implantation of aortic valve endoprosthesis
+∞
10.4
10
*
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
+∞
10.4
10
*
FPJ
NOMESCO Finland
Review and replacement of pacemaker or internal defibrillator device or electrode
+∞
10.4
10
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
+∞
10.4
10
*
FPE36
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with ventricular electrodes
+∞
10.4
10
*
FPG42
NOMESCO Finland
Replacement of electrode(s) in transvenous cardioverter-defibrillator
+∞
10.4
10
*
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
+∞
10.4
10
*
4289X
ICD-9 Finland
Heart failure, unspecified
+∞
10.4
10
*
Z3226
NOMESCO Finland
Physiotherapist
1.5
10.4
377
2641
R04.2
ICD-10 Finland
Haemoptysis
2.5
10.4
77
309
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
10.3
154
839
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
10.3
263
1693
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
10.3
116
568
Z71.8
ICD-10 Finland
Other specified counselling
1.5
10.2
417
2990
J01FA06
ATC
roxithromycin; oral
1.3
10.2
826
6701
Z01.7
ICD-10 Finland
Laboratory examination
1.7
10.1
219
1344
SPAT1310
SPAT
Counselling related to known health issue
1.4
10.1
629
4883
E0000UV
ATC
NA
1.4
10.1
779
6267
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
10.0
1380
12095
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.0
10.0
57
193
I20.0
ICD-10 Finland
Unstable angina
5.3
10.0
29
55
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
9.9
135
715
M25.5
ICD-10 Finland
Pain in joint
1.4
9.8
527
3984
J01FA10
ATC
azithromycin; systemic
1.3
9.8
1065
9007
R60.0
ICD-10 Finland
Localized oedema
1.6
9.8
229
1440
JN4DR
NOMESCO Finland
Whole body metabolic PET with CT
26.1
9.8
13
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
9.8
136
723
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.8
9.8
40
107
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
9.8
227
1426
TKC20
NOMESCO Finland
Catheterisation of bladder
1.9
9.7
149
820
SPAT1211
SPAT
Application of soft bandage
1.8
9.7
180
1059
I20.01
ICD-10 Finland
Unstable angina
2.7
9.7
66
253
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
3.0
9.5
52
174
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.5
269
1778
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
9.5
210
1300
K04
ICPC
Palpitations/awareness of heart
2.4
9.5
76
319
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.6
9.5
41
115
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.0
9.5
115
582
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
9.5
611
4770
I51.9
ICD-10 Finland
Heart disease, unspecified
100.3
9.4
10
*
E66.01
ICD-10 Finland
Obesity due to excess calories
2.0
9.4
117
599
342
Kela drug reimbursment
Dronedarone
+∞
9.4
9
*
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
+∞
9.4
9
*
I45.6
ICD-10 Finland
Pre-excitation syndrome
+∞
9.4
9
*
4262A
ICD-9 Finland
Conduction disorders, Left bundle branch hemiblock
+∞
9.4
9
*
AC4
HP
MVP
+∞
9.4
9
*
4276B
ICD-9 Finland
Cardiac dysrhythmias, Premature beats[EXTRASYSTOLIA VENTRICULARIS]
+∞
9.4
9
*
AB1
HP
AVR mechanical
+∞
9.4
9
*
FPJ12
NOMESCO Finland
Revision of biventricular CRT-P (DDDR) generator
+∞
9.4
9
*
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.4
9.4
414
3015
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
21.8
9.3
13
6
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.4
9.3
77
328
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
3.5
9.3
41
117
M54
ICD-10 Finland
Dorsalgia
1.7
9.3
195
1191
XF405
NOMESCO Finland
Symptom ECG
10.7
9.3
17
16
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
9.3
134
725
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
9.5
9.3
18
19
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
9.2
105
519
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
9.2
342
2406
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.2
9.1
87
398
I20.9
ICD-10 Finland
Angina pectoris, unspecified
3.9
9.1
36
94
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
9.1
116
597
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
9.1
132
715
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
3.2
9.0
46
147
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
9.0
269
1800
C08DB01
ATC
diltiazem; oral
2.0
8.9
109
555
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.9
1339
11791
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
8.8
296
2031
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.8
489
3714
WZC30
NOMESCO Finland
Teaching
1.5
8.8
271
1828
R00.8
ICD-10 Finland
Other and unspecified abnormalities of heart beat
4.6
8.8
29
64
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
8.8
128
696
A10AE04
ATC
insulin glargine; parenteral
1.7
8.7
166
985
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
8.7
98
480
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.6
8.7
63
250
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
50.1
8.7
10
*
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
8.7
261
1748
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.6
885
7389
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.8
8.6
140
788
H26.4
ICD-10 Finland
After-cataract
1.6
8.5
216
1385
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
6.9
8.5
20
29
AP3
HP
Catheterization of the right and left side of the heart
27.6
8.5
11
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.3
8.5
41
127
S22.3
ICD-10 Finland
Fracture of rib
1.9
8.4
123
667
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
90.3
8.4
9
*
FA1AC
NOMESCO Finland
Upper cavography
90.3
8.4
9
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.4
1174
10207
R01AD09
ATC
mometasone; nasal
1.3
8.4
820
6795
FMD22
NOMESCO Finland
Percutaneous transluminal replacement of aortic valve using biological prosthesis
+∞
8.3
8
*
4254A
ICD-9 Finland
Cardiomyopathy, Other primary cardiomyopathies
+∞
8.3
8
*
PH3AC
NOMESCO Finland
Flebography of internal organs with X-ray
+∞
8.3
8
*
C01BD07
ATC
dronedarone; oral
+∞
8.3
8
*
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
+∞
8.3
8
*
AQ2
HP
Electrophysiological electroanatomical examination
+∞
8.3
8
*
WX930
NOMESCO Finland
Thepapeutic hypothermia
+∞
8.3
8
*
AT4
HP
Physiological pacemaker replacement DDD (R)
+∞
8.3
8
*
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
+∞
8.3
8
*
AR1
HP
Catheter ablation of arrhythmia, target: AV node reentry activation (AVNRT)
+∞
8.3
8
*
C02AC05
ATC
moxonidine; oral
2.1
8.3
89
430
Z01.2
ICD-10 Finland
Dental examination
1.3
8.3
727
5928
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
5.8
8.3
22
38
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
2.7
8.3
54
204
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
8.2
180
1113
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
8.2
85
403
N05CF01
ATC
zopiclone; oral
1.3
8.2
689
5585
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
3.1
8.2
42
136
N03AX16
ATC
pregabalin; oral
1.4
8.2
463
3525
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
7.5
8.1
18
24
TK800
NOMESCO Finland
Hemodialysis
3.3
8.1
39
120
C08CA07
ATC
nisoldipine; oral
3.7
8.1
33
89
J45
ICD-10 Finland
Asthma
1.7
8.1
167
1014
ZXD00
NOMESCO Finland
Emergency procedure
2.4
8.1
64
269
WX740
NOMESCO Finland
Nitrogen oxide therapy
33.4
8.1
10
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
8.1
468
3574
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.1
163
984
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
8.1
879
7384
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
8.0
309
2187
4029A
ICD-9 Finland
Hypertensive heart disease, Unspecified[DECOMPENSATIO CORDIS NON INDICATA (WHO II)]
8.9
8.0
16
18
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
3.7
8.0
33
90
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.0
380
2804
SPAT1229
SPAT
Assessment of need for aid
1.7
7.9
165
1004
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.9
1036
8911
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.9
506
3931
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
7.9
275
1908
K30
ICD-10 Finland
Functional dyspepsia
1.6
7.9
189
1199
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.8
476
3664
A08
ICPC
Swelling
2.1
7.8
80
380
E66.9
ICD-10 Finland
Obesity, unspecified
2.5
7.8
57
228
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.8
600
4794
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
7.7
966
8246
Z94.1
ICD-10 Finland
Heart transplant status
45.1
7.7
9
*
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
15.0
7.7
12
8
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
7.7
350
2559
K57
ICD-10 Finland
Diverticular disease of intestine
2.7
7.7
49
182
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.6
707
5796
R05
ICPC
Cough
1.4
7.5
410
3093
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
7.5
477
3699
4130X
ICD-9 Finland
Angina pectoris, Angina decubitus[ANGINA PECTORIS (""""EFFORT ANGINA""""),MÄÄRITTELEMÄT]
2.9
7.5
43
149
N18.8
ICD-10 Finland
Other chronic renal failure
2.6
7.4
52
204
H02AB04
ATC
methylprednisolone; systemic
1.5
7.4
278
1953
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
80.3
7.4
8
*
N17
ICPC
Vertigo/dizziness
1.5
7.4
222
1487
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.4
354
2610
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.3
7.4
67
301
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.4
248
1706
XG410
NOMESCO Finland
Flow-volume spirometry
2.1
7.4
80
391
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
7.3
98
517
I42.7
ICD-10 Finland
Cardiomyopathy due to drugs and other external agents
+∞
7.3
7
*
42728
ICD-8 Finland
Symptomatic heart disease, Dissociatio cordis alia
+∞
7.3
7
*
FPJ23
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with ventricular electrodes
+∞
7.3
7
*
4278X
ICD-9 Finland
Cardiac dysrhythmias, Other specified cardiac dysrhythmias[DYSRHYTMIAE CORDIS ALIA DEFINITA]
+∞
7.3
7
*
I42.6
ICD-10 Finland
Alcoholic cardiomyopathy
+∞
7.3
7
*
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
+∞
7.3
7
*
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
+∞
7.3
7
*
I46.9
ICD-10 Finland
Cardiac arrest, unspecified
+∞
7.3
7
*
ASX
HP
Other pacemaker insertion
+∞
7.3
7
*
I49
ICD-10 Finland
Other cardiac arrhythmias
4.2
7.3
26
63
Z13.6
ICD-10 Finland
Special screening examination for cardiovascular disorders
4.9
7.3
22
45
R03BA01
ATC
beclometasone; inhalant
1.5
7.2
266
1864
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
7.2
170
1073
C10AA03
ATC
pravastatin; oral
1.7
7.2
152
931
SPAT1260
SPAT
Consultation of another employee
1.4
7.2
332
2434
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
5.4
7.2
20
37
K28
ICPC
Limited function/disability (K)
2.7
7.2
46
170
A02BC05
ATC
esomeprazole; systemic
1.3
7.2
797
6688
FL1AC
NOMESCO Finland
Left cardioangiography
3.3
7.2
34
105
R1420
NOMESCO Finland
Assessment of rehabilitation needs and/or compilation of rehabilitation plan
30.1
7.1
9
*
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
4.4
7.1
24
55
E87.5
ICD-10 Finland
Hyperkalaemia
3.3
7.1
33
100
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.8
7.0
124
721
A41.8
ICD-10 Finland
Other specified sepsis
3.1
7.0
35
113
SPAT1312
SPAT
General health counselling
1.3
7.0
595
4818
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
6.9
134
800
AA1
HP
Conventional CABG
2.8
6.9
41
147
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.9
6.9
97
523
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.8
580
4690
XF602
NOMESCO Finland
Bloodpressure monitoring
4.4
6.8
23
53
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.1
6.8
75
369
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
6.8
212
1437
GD2SN
NOMESCO Finland
Lung ventilation SPECT
5.7
6.7
18
32
A11CC03
ATC
alfacalcidol; systemic
2.9
6.7
39
137
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
6.7
82
421
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
2.0
6.7
84
435
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
6.7
35
116
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.7
796
6719
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.4
6.7
51
211
WX730
NOMESCO Finland
Conventional respirator
3.3
6.6
31
95
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.6
257
1818
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.3
6.6
56
242
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.7
6.6
43
162
A10BH01
ATC
sitagliptin; oral
1.5
6.6
188
1246
A04
ICPC
Weakness/tiredness general
1.5
6.6
217
1484
D82
ICPC
Teeth/gum disease
1.3
6.6
580
4710
Z50.0
ICD-10 Finland
Cardiac rehabilitation
3.6
6.6
27
75
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
6.6
595
4851
A10BK03
ATC
empagliflozin; oral
1.7
6.5
130
783
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
10.0
6.5
12
12
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
10.0
6.5
12
12
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
6.5
90
482
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
6.5
181
1193
S01BC05
ATC
ketorolac; ophthalmic
1.9
6.5
88
468
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
6.5
506
4038
R03DA04
ATC
theophylline; systemic, rectal
1.7
6.5
118
693
GD1UN
NOMESCO Finland
Lung circulation SPECT
6.2
6.5
16
26
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
70.0
6.4
7
*
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
70.0
6.4
7
*
I51.7
ICD-10 Finland
Cardiomegaly
70.0
6.4
7
*
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
70.0
6.4
7
*
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
70.0
6.4
7
*
SPAT1081
SPAT
Cardiorespiratory global assessment
1.8
6.4
110
637
82
HP
Single vessel balloon catheter extension
2.5
6.4
46
186
AN4
HP
Balloon angioplasty and drug eluding stent
2.1
6.4
67
322
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.3
702
5870
SPAT1281
SPAT
Other administrative function
1.6
6.3
143
892
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.3
202
1374
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.6
6.3
138
858
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
9.3
6.3
12
13
A02BA02
ATC
ranitidine; systemic
1.3
6.3
410
3186
130
Kela drug reimbursment
Malignant tumour
0.6
6.3
89
1467
R03BA05
ATC
fluticasone; inhalant
1.4
6.3
316
2352
5273
FHL
Repair with flap prosthesis or graft
+∞
6.2
6
*
21
HP
Aortic Valve Replacement (AVR)
+∞
6.2
6
*
4241B
ICD-9 Finland
Other diseases of endocardium, Aortic valve disorders[STENOSIS VALVULAE AORTAE (NON RHEUMATICA)]
+∞
6.2
6
*
FPJ22
NOMESCO Finland
Revision of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
6.2
6
*
4259X
ICD-9 Finland
Cardiomyopathy, Secondary cardiomyopathy, unspecified
+∞
6.2
6
*
4270A
ICD-9 Finland
Cardiac dysrhythmias, Paroxysmal supraventricular tachycardia
+∞
6.2
6
*
FPE10
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial electrode
+∞
6.2
6
*
I35
ICD-10 Finland
Nonrheumatic aortic valve disorders
+∞
6.2
6
*
4240A
ICD-9 Finland
Other diseases of endocardium, Mitral valve disorders[INSUFFICIENTIA VALVULAE MITRALIS (NON RHEUMATICA)]
+∞
6.2
6
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
6.2
6
*
I47.0
ICD-10 Finland
Re-entry ventricular arrhythmia
+∞
6.2
6
*
FPF00
NOMESCO Finland
Implantation of epicardial pacemaker with ventricular electrode
+∞
6.2
6
*
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.2
1023
8954
I95.2
ICD-10 Finland
Hypotension due to drugs
4.3
6.2
21
49
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.9
6.2
78
406
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.0
6.2
71
356
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
4.1
6.2
22
54
R74
ICPC
Upper respiratory infection acute
1.3
6.2
401
3111
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
6.2
174
1150
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.7
6.2
115
683
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
6.2
202
1384
R03BA02
ATC
budesonide; inhalant
1.4
6.2
312
2325
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
6.1
344
2607
C10AA04
ATC
fluvastatin; oral
1.5
6.1
190
1285
N02AX02
ATC
tramadol; systemic, rectal
1.2
6.1
875
7538
K59.0
ICD-10 Finland
Constipation
1.7
6.1
118
709
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.7
6.1
119
713
ZXA10
NOMESCO Finland
Bilateral
1.4
6.1
377
2904
61
HP
Catheterization and pressure measurement of the left side of the heart
3.0
6.1
32
108
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.1
826
7073
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
6.0
72
367
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.9
6.0
18
37
C01BA01
ATC
quinidine; oral
10.0
6.0
11
11
XKD00
NOMESCO Finland
Uroflowmetry
1.4
6.0
352
2685
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.4
6.0
26
76
Mortality – FinRegistry
↥Association
Association between endpoint I9_LBBB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_LBBB | 1.485 [1.31, 1.69] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.049 |
During the follow-up period (1.1.1998 — 31.12.2019), 1404 out of 6319 females with I9_LBBB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_LBBB | 1.602 [1.39, 1.85] | < 0.001 |
| Birth year | 0.983 [0.97, 0.99] | < 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 1722 out of 5910 males with I9_LBBB died.
Mortality risk
Mortality risk for people of age
years, who have I9_LBBB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.122% | 0.242% |
| 5 | 0.711% | 1.661% |
| 10 | 1.908% | 4.146% |
| 15 | 3.579% | 8.024% |
| 20 | 6.132% | 13.259% |
Relationships between endpoints
↥Index endpoint: I9_LBBB – Left bundle-branch block
GWS hits: 5
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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