Left bundle-branch block

I9_LBBB

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

2836

4. Check minimum number of events

None

2836

5. Include endpoints

None

2836

6. Filter based on genotype QC (FinnGen only)

2836

Control definitions (FinnGen only)

Control exclude
I9_OTHHEART

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17107 8747 8259
Only index persons 14924 7794 7130
Unadjusted period prevalence (%)
Whole population 0.24 0.25 0.23
Only index persons 0.28 0.29 0.27
Median age at first event (years)
Whole population 69.91 70.38 69.35
Only index persons 69.06 69.43 68.66

-FinnGen-

Key figures

All Female Male
Number of individuals 2836 1414 1422
Unadjusted period prevalence (%) 0.55 0.48 0.63
Median age at first event (years) 68.17 66.91 69.42

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2492
Matched controls
24918
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C07AB07
ATC
bisoprolol; oral
5.8
323.0
1659
6400
I50.9
ICD-10 Finland
Heart failure, unspecified
111.8
323.0
758
97
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
7.3
323.0
1069
2310
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
+∞
323.0
406
*
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
298.7
323.0
593
26
I48
ICD-10 Finland
Atrial fibrillation and flutter
101.5
323.0
739
103
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
8.4
323.0
830
1392
I50.1
ICD-10 Finland
Left ventricular failure
1513.2
323.0
488
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
15.0
323.0
1248
1565
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
434.2
323.0
456
13
I42.0
ICD-10 Finland
Dilated cardiomyopathy
5045.8
323.0
432
*
I50.0
ICD-10 Finland
Congestive heart failure
201.9
323.0
348
20
I44.7
ICD-10 Finland
Left bundle-branch block, unspecified
6096.4
323.0
2057
18
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
430.6
323.0
453
13
207
Kela drug reimbursment
Chronic arrhythmias
160.8
323.0
481
37
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
413.6
299.4
295
8
201
Kela drug reimbursment
Chronic cardiac insufficiency
31.9
276.9
372
136
I44.4
ICD-10 Finland
Left anterior fascicular block
1467.3
275.0
263
*
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
11.7
249.4
491
510
C03CA01
ATC
furosemide; systemic
4.8
248.5
1071
3360
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
833.7
235.4
228
*
C03DA01
ATC
spironolactone; oral
8.8
232.0
544
770
XF404
NOMESCO Finland
Ambulatory ECG
12.6
224.8
424
398
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
2144.3
217.8
208
*
B01AA03
ATC
warfarin; systemic
6.5
201.7
590
1137
TFP20
NOMESCO Finland
Cardiodefibrillation
151.9
198.8
209
15
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
92.2
190.7
211
25
I44.2
ICD-10 Finland
Atrioventricular block, complete
+∞
189.0
179
*
I35.0
ICD-10 Finland
Aortic (valve) stenosis
47.9
185.4
227
52
C09AA05
ATC
ramipril; oral
3.6
162.3
950
3614
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
122.2
159.3
171
15
I48.0
ICD-10 Finland
Paroxysmal atrial fibrillation
121.5
158.3
170
15
B01AF02
ATC
apixaban; oral
13.4
156.1
283
236
I44.6
ICD-10 Finland
Other and unspecified fascicular block
1590.9
152.7
147
*
I49.3
ICD-10 Finland
Ventricular premature depolarization
20.9
151.0
229
120
C01AA05
ATC
digoxin; systemic
15.9
150.5
253
176
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
145.5
1318
6743
I44.0
ICD-10 Finland
Atrioventricular block, first degree
118.7
144.9
156
14
AN1
HP
Coronary angiography
5.0
138.8
498
1177
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.5
134.0
783
2887
I49.5
ICD-10 Finland
Sick sinus syndrome
344.7
131.8
132
*
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
123.5
130.5
140
12
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
3.2
120.8
816
3306
I50
ICD-10 Finland
Heart failure
29.0
115.4
158
58
XF640
NOMESCO Finland
NA
18.1
114.0
181
107
R06.0
ICD-10 Finland
Dyspnoea
3.1
113.3
772
3120
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
6.8
112.6
302
492
K78
ICPC
Atrial fibrillation/flutter
16.5
111.2
183
119
R07.4
ICD-10 Finland
Chest pain, unspecified
2.9
109.2
855
3775
C01BD01
ATC
amiodarone; systemic
167.3
107.1
112
7
FPE96
NOMESCO Finland
Other implantation or replacement of transvenous cardiac pacemaker
1072.1
106.1
103
*
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
9.6
105.9
226
256
GD1LA
NOMESCO Finland
GD
184.3
102.1
106
6
FPG96
NOMESCO Finland
Other implantation of permanent cardioverter-defibrillator
+∞
101.7
97
*
I47.2
ICD-10 Finland
Ventricular tachycardia
268.6
101.5
103
*
289
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
99.6
95
*
I44.1
ICD-10 Finland
Atrioventricular block, second degree
263.0
99.4
101
*
I48.2
ICD-10 Finland
Chronic atrial fibrillation
+∞
95.4
91
*
TFP34
NOMESCO Finland
Electrophysiological investigation
867.0
86.1
84
*
I48.1
ICD-10 Finland
Persistent atrial fibrillation
437.0
85.6
85
*
I47.1
ICD-10 Finland
Supraventricular tachycardia
32.8
83.2
110
35
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
219.7
82.8
85
*
381
Kela drug reimbursment
Combination product containing sacubitril and valsartan
+∞
81.7
78
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
81.1
454
1540
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
77.9
79.7
90
12
C09DX04
ATC
valsartan and sacubitril; oral
+∞
79.6
76
*
XF402
NOMESCO Finland
ECG with work load test
3.8
77.8
362
1057
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
57.6
75.4
89
16
FPE30
NOMESCO Finland
Replacement of transvenous cardiac pacemaker pulse generator
749.7
74.6
73
*
I34.00
ICD-10 Finland
Mitral (valve) incompetence NOS or of specified cause, except rheumatic
+∞
72.2
69
*
C01DA14
ATC
isosorbide mononitrate; oral
2.9
72.1
506
2000
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
89.4
70.3
78
9
AS4
HP
Physiological pacemaker insertion DDD (R)
+∞
70.1
67
*
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
243.3
69.6
71
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
6.4
68.1
188
313
PH1AC
NOMESCO Finland
Flebography of over extremity with X-ray
335.6
65.8
66
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.7
62.1
485
2029
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
61.9
1588
11517
FPE37
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
+∞
57.5
55
*
FME20
NOMESCO Finland
Transvenous aortic valve replacement via femoral artery
+∞
56.5
54
*
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
3.2
56.1
322
1094
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
52.1
55.2
66
13
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
4.8
54.7
193
428
FPE25
NOMESCO Finland
Implantation of biventricular cardiac pacemaker, atrial and ventricular electrodes, CRT-P (DDDR)
+∞
53.3
51
*
C10AA05
ATC
atorvastatin; oral
2.0
52.9
1065
6863
I34.1
ICD-10 Finland
Mitral (valve) prolapse
62.4
52.5
61
10
4263A
ICD-9 Finland
Conduction disorders, Other left bundle branch block
+∞
52.3
50
*
I45.3
ICD-10 Finland
Trifascicular block
518.1
51.6
51
*
K77
ICPC
Heart failure
18.5
50.8
79
44
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.3
48.7
528
2595
TFP00
NOMESCO Finland
Temporary use of transvenous or epicardial pacemaker
106.1
47.9
52
5
WX892
NOMESCO Finland
Monitored bed care
3.8
47.3
213
595
R55
ICD-10 Finland
Syncope and collapse
2.8
45.6
330
1299
FMD10
NOMESCO Finland
Replacement of aortic valve using biological prosthesis
+∞
44.9
43
*
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
445.2
44.3
44
*
4273A
ICD-9 Finland
Cardiac dysrhythmias, Atrial fibrillation and flutter
+∞
43.9
42
*
FPG32
NOMESCO Finland
Implantation of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
43.9
42
*
I71.2
ICD-10 Finland
Thoracic aortic aneurysm, without mention of rupture
9.1
43.7
94
107
I25.2
ICD-10 Finland
Old myocardial infarction
3.5
43.0
212
638
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.1
41.5
574
3123
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.9
40.5
178
486
I49.1
ICD-10 Finland
Atrial premature depolarization
11.5
38.7
73
65
I44.5
ICD-10 Finland
Left posterior fascicular block
+∞
38.6
37
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
38.0
409
1981
81
HP
Angiography of the heart and coronary arteries
3.4
38.0
200
632
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
5.0
37.8
127
267
M04AA01
ATC
allopurinol; systemic
2.4
37.7
348
1562
TFP47
NOMESCO Finland
Ablation or modification of the AV-node
+∞
37.6
36
*
I45.2
ICD-10 Finland
Bifascicular block
131.9
36.8
39
*
FN1AD
NOMESCO Finland
CT of coronary arteries
10.4
36.3
72
71
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.3
36.2
197
638
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.2
36.0
199
652
C07AB02
ATC
metoprolol; systemic
2.0
35.7
525
2907
FPE40
NOMESCO Finland
Replacement of transvenous cardiac pacemaker electrode
+∞
35.5
34
*
I46.0
ICD-10 Finland
Cardiac arrest with successful resuscitation
+∞
35.5
34
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
5.5
35.0
107
202
N02BE01
ATC
paracetamol; systemic, rectal
1.9
34.2
2048
17683
AP1
HP
Catheterization of the left side of the heart
8.3
33.8
76
94
K80
ICPC
Cardiac arrhythmia NOS
3.6
33.7
162
476
I49.4
ICD-10 Finland
Other and unspecified premature depolarization
7.3
33.6
82
115
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
5.6
33.5
101
188
I44.3
ICD-10 Finland
Other and unspecified atrioventricular block
+∞
33.4
32
*
R00.1
ICD-10 Finland
Bradycardia, unspecified
6.6
33.2
87
135
I47.9
ICD-10 Finland
Paroxysmal tachycardia, unspecified
31.2
32.6
43
14
A02BC02
ATC
pantoprazole; systemic
1.7
32.4
1536
12225
C07AA07
ATC
sotalol; systemic
5.9
32.2
92
160
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
31.9
591
3546
I45.0
ICD-10 Finland
Right fascicular block
34.7
31.9
41
12
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
114.8
31.7
34
*
J01DB01
ATC
cefalexin; oral
1.7
31.6
1859
15669
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
4.2
31.2
124
309
I42.8
ICD-10 Finland
Other cardiomyopathies
+∞
30.3
29
*
FPJ24
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with atrial and ventricular electrodes
+∞
30.3
29
*
H02AB06
ATC
prednisolone; systemic
1.6
30.0
1087
7966
AQ1
HP
Conventional electrophysiological examination
305.8
29.9
30
*
TFP44
NOMESCO Finland
Ablation treatment of typical atrial flutter
+∞
29.2
28
*
R53
ICD-10 Finland
Malaise and fatigue
1.9
29.2
462
2607
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
3.6
29.0
136
392
B01AC04
ATC
clopidogrel; oral
2.0
28.9
424
2322
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.7
28.9
214
847
R03AC02
ATC
salbutamol; inhalant
1.6
28.8
1137
8494
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
11.0
28.8
55
51
C01BC04
ATC
flecainide; systemic
29.6
28.5
38
13
I42
ICD-10 Finland
Cardiomyopathy
+∞
28.2
27
*
I20.09
ICD-10 Finland
Unstable angina
3.2
28.1
158
521
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.3
27.8
272
1245
B01AF01
ATC
rivaroxaban; oral
2.3
27.6
266
1210
J01CA04
ATC
amoxicillin; systemic
1.6
27.6
1768
14896
ASB
HP
Insertion of a biventricular physiological pacemaker DDD (R)
+∞
27.1
26
*
XFE00
NOMESCO Finland
Epicardial ultrasonography
6.9
26.9
68
101
I45.9
ICD-10 Finland
Conduction disorder, unspecified
76.0
26.8
30
*
R00.2
ICD-10 Finland
Palpitations
3.2
26.8
146
473
I36.1
ICD-10 Finland
Nonrheumatic tricuspid (valve) insufficiency
273.8
26.8
27
*
Z95.3
ICD-10 Finland
Presence of xenogenic heart valve
141.5
26.7
28
*
C10AA01
ATC
simvastatin; oral
1.6
26.6
1142
8655
I45.1
ICD-10 Finland
Other and unspecified right bundle-branch block
52.2
26.2
31
6
TFP35
NOMESCO Finland
Electroanatomical mapping
+∞
26.1
25
*
WX872
NOMESCO Finland
Intensive care
3.7
25.7
115
319
XF409
NOMESCO Finland
Other special ECG
44.8
25.5
31
7
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
25.2
194
784
FPG40
NOMESCO Finland
Replacement of pulse generator in transvenous cardioverter-defibrillator
+∞
25.0
24
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
25.0
736
5032
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
3.0
24.8
152
531
K84
ICPC
Heart disease other
5.3
24.8
77
149
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
70.6
24.8
28
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
24.6
198
820
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
24.6
461
2747
R02
ICPC
Shortness of breath/dyspnoea
2.2
24.5
272
1322
M10.9
ICD-10 Finland
Gout, unspecified
2.8
24.5
166
622
K83
ICPC
Heart valve disease NOS
29.4
24.1
32
11
TFP46
NOMESCO Finland
Ablation treatment of atrial fibrillation
+∞
24.0
23
*
AB2
HP
AVR bio, stent
+∞
24.0
23
*
I41.8*D86.8
ICD-10 Finland
Sarcoid myocarditis
+∞
24.0
23
*
R07.3
ICD-10 Finland
Other chest pain
2.3
23.7
228
1034
I49.0
ICD-10 Finland
Ventricular fibrillation and flutter
242.1
23.7
24
*
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
23.6
561
3598
I49.8
ICD-10 Finland
Other specified cardiac arrhythmias
6.4
23.4
62
99
I20.00
ICD-10 Finland
Unstable angina
4.1
23.1
93
236
I34.9
ICD-10 Finland
Nonrheumatic mitral valve disorder, unspecified
+∞
22.9
22
*
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
+∞
22.9
22
*
FPG30
NOMESCO Finland
Implantation of cardioverter-defibrillator with ventricular electrode
+∞
22.9
22
*
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.9
22.7
145
522
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
6.2
22.4
61
101
I34.0
ICD-10 Finland
Mitral (valve) insufficiency
15.8
22.3
36
23
B01AE07
ATC
dabigatran etexilate; oral
4.7
22.3
76
164
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
21.9
630
4249
AS6
HP
Biventricular physiological heart failure pacemaker insertion DDD (R)
+∞
21.9
21
*
TFC25
NOMESCO Finland
Transseptal catheterisation of left atrium or ventricle
+∞
21.9
21
*
G47.3
ICD-10 Finland
Sleep apnoea
1.8
21.9
447
2726
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
21.7
238
1147
I11
ICD-10 Finland
Hypertensive heart disease
20.2
21.7
32
16
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
21.0
832
6075
M10
ICD-10 Finland
Gout
3.1
21.0
117
386
FPE24
NOMESCO Finland
Implantation of biventricular cardiac pacemaker, ventricular electrodes, CRT-P (VVIR)
+∞
20.9
20
*
AP4
HP
Myocardial biopsy
+∞
20.9
20
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
20.9
1040
8006
TFP30
NOMESCO Finland
Cathetric examination for cardiac arrythmia
77.4
20.7
23
*
C07AG02
ATC
carvedilol; oral
2.5
20.6
163
667
B01AF03
ATC
edoxaban; oral
17.0
20.5
32
19
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
20.4
646
4461
SPAT1263
SPAT
Sampling
1.5
20.2
900
6742
A10BK01
ATC
dapagliflozin; oral
3.0
20.1
118
404
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
19.8
225
1100
73
HP
Initial pacemaker installation
+∞
19.8
19
*
250
Kela drug reimbursment
NA
+∞
19.8
19
*
C08CA01
ATC
amlodipine; oral
1.5
19.4
844
6272
SPAT1097
SPAT
Recording of ECG
1.8
19.3
336
1938
WX110
NOMESCO Finland
Local anesthesy
1.5
19.1
1426
11865
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
19.1
483
3127
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
18.9
120
432
AA1AD
NOMESCO Finland
CT of head and brain
1.6
18.9
523
3472
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.8
18.9
379
2290
ATX
HP
Other pacemaker replacement or related action, such as cord removal or replacement
+∞
18.8
18
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
18.6
509
3366
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
18.4
373
2260
PD5AD
NOMESCO Finland
CT of aorta
6.4
18.4
48
76
J01MA12
ATC
levofloxacin; systemic
1.7
18.3
426
2691
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.5
18.2
142
578
C09CA03
ATC
valsartan; oral
2.1
18.2
222
1119
R00.0
ICD-10 Finland
Tachycardia, unspecified
3.7
18.1
80
222
S18
ICPC
Laceration/cut
1.5
17.9
941
7253
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.8
17.9
117
428
M79.6
ICD-10 Finland
Pain in limb
1.5
17.8
754
5541
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
17.8
273
1505
TFJ02
NOMESCO Finland
Muscle biopsy of heart
+∞
17.7
17
*
42798
ICD-8 Finland
Symptomatic heart disease, Alia arrhytmia definita
+∞
17.7
17
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
17.6
335
1991
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
7.8
17.6
40
52
I42.1
ICD-10 Finland
Obstructive hypertrophic cardiomyopathy
181.1
17.5
18
*
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.8
17.5
116
430
FP4B5
NOMESCO Finland
ECG, prolonged recording (24 h)
18.7
17.3
26
14
K99
ICPC
Cardiovascular disease other
4.6
17.3
60
133
71
HP
Electrophysiological Special Examination
42.3
17.3
21
5
R42
ICD-10 Finland
Dizziness and giddiness
1.6
17.1
485
3233
C09AA02
ATC
enalapril; systemic
1.6
17.1
485
3233
1CX08
NOMESCO Finland
NA
50.3
17.0
20
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
16.8
439
2859
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
16.7
253
1387
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.0
16.6
96
326
I35.9
ICD-10 Finland
Aortic valve disorder, unspecified
90.6
16.6
18
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.5
16.5
132
545
FN1CB
NOMESCO Finland
Coronary flow reserve measurement with pressure wire
4.5
16.5
58
131
WX722
NOMESCO Finland
PEEP
2.8
16.1
107
396
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
16.0
269
1529
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
16.0
356
2215
C09AA04
ATC
perindopril; oral
2.4
15.9
134
569
WX002
NOMESCO Finland
Sedation and analgesia
1.6
15.8
445
2952
I51.4
ICD-10 Finland
Myocarditis, unspecified
+∞
15.6
15
*
FPJ00
NOMESCO Finland
Revision of pacemaker pulse generator or electrode
+∞
15.6
15
*
FKB10
NOMESCO Finland
Annuloplasty of mitral valve for insufficiency using ring
+∞
15.6
15
*
R05
ICD-10 Finland
Cough
1.6
15.6
422
2771
C08DA01
ATC
verapamil; systemic
3.3
15.1
76
235
FM3CN
NOMESCO Finland
Heart perfusion isotope imaging both at rest and with exercise
23.5
15.1
21
9
I71.9
ICD-10 Finland
Aortic aneurysm of unspecified site, without mention of rupture
6.3
14.8
39
63
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.6
14.7
110
438
FPJ04
NOMESCO Finland
Revision of pacemaker generator with atrial and ventricular electrodes
+∞
14.6
14
*
R04.0
ICD-10 Finland
Epistaxis
2.2
14.5
147
685
AS2
HP
Ventricular pacemaker insertion VVI (R)
150.8
14.5
15
*
I48.4
ICD-10 Finland
Atypical atrial flutter
150.8
14.5
15
*
C03AA03
ATC
hydrochlorothiazide; oral
1.9
14.4
231
1294
R4110
NOMESCO Finland
Physiotherapy
1.5
14.2
572
4122
C10AA07
ATC
rosuvastatin; oral
1.5
14.2
557
3991
Q23.11
ICD-10 Finland
Bicuspid aortic valve
30.2
13.9
18
6
C08CA13
ATC
lercanidipine; oral
1.7
13.9
293
1790
C09CA06
ATC
candesartan; oral
1.6
13.8
452
3104
AP2
HP
Catheterization of the right side of the heart
53.6
13.8
16
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
13.8
933
7442
A46
ICD-10 Finland
Erysipelas
1.7
13.8
284
1722
R03BB04
ATC
tiotropium bromide; inhalant
1.8
13.7
236
1351
L28
ICPC
Limited function/disability (L)
1.6
13.7
363
2367
N19
ICD-10 Finland
Unspecified kidney failure
2.9
13.6
80
277
FXZ00
NOMESCO Finland
Off-pump cardiac operation
12.1
13.6
24
20
74
HP
Initial installation of the atrial pacemaker
+∞
13.5
13
*
FK1BT
NOMESCO Finland
Implantation of cardiac pacemaker with X-ray guidance
+∞
13.5
13
*
A98
ICPC
Health maint/preventive medicine
1.6
13.5
2191
20448
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
13.5
769
5937
FM1JR
NOMESCO Finland
Heart, extensive metabolic PET with CT
140.7
13.5
14
*
XF600
NOMESCO Finland
Bloodpressure measurement
2.3
13.3
126
570
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.0
13.0
173
904
M10.0
ICD-10 Finland
Idiopathic gout
2.9
12.9
77
269
T90
ICPC
Diabetes non-insulin dependent
1.5
12.8
508
3642
D64.9
ICD-10 Finland
Anaemia, unspecified
1.8
12.7
217
1240
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
12.7
552
4031
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
12.6
212
1204
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
12.5
706
5427
UJF32
NOMESCO Finland
Coloscopy
1.5
12.4
557
4089
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
12.4
674
5140
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
12.3
794
6248
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.9
12.3
187
1026
C09CA01
ATC
losartan; oral
1.5
12.2
533
3892
SPAT1325
SPAT
Vaccination
1.4
12.1
780
6127
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
2.3
12.1
112
500
SPAT1104
SPAT
Monitoring of emergency patient
2.1
12.1
134
650
J01DA01
ATC
[U] cefalexin; systemic
1.4
12.0
1325
11373
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
12.0
515
3747
M54.5
ICD-10 Finland
Low back pain
1.4
11.9
626
4735
J01FF01
ATC
clindamycin; systemic
1.5
11.8
527
3865
205
Kela drug reimbursment
Chronic hypertension
1.4
11.7
660
5058
J01AA02
ATC
doxycycline; systemic
1.4
11.7
1746
15696
B01AB05
ATC
enoxaparin; parenteral
1.4
11.7
629
4777
SPAT1254
SPAT
Administration of medicine
1.6
11.7
293
1877
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
11.7
285
1815
FM1DE
SPAT
NA
30.1
11.6
15
5
A10BA02
ATC
metformin; oral
1.4
11.6
609
4605
SPAT1262
SPAT
Handing over of treatment supplies
1.5
11.6
396
2740
H02AB07
ATC
prednisone; oral
1.6
11.5
312
2044
I48.3
ICD-10 Finland
Typical atrial flutter
+∞
11.5
11
*
FPH10
NOMESCO Finland
Open removal of transvenous cardiac pacemaker or cardioverter-defibrillator
+∞
11.5
11
*
TFP40
NOMESCO Finland
Ablation treatment for a-v node re-entry activation
+∞
11.5
11
*
I41.8
ICD-10 Finland
Myocarditis in other diseases classified elsewhere
+∞
11.5
11
*
AS8
HP
Physiological arrhythmia pacemaker insertionDDD (R) S
+∞
11.5
11
*
C10AX09
ATC
ezetimibe; oral
1.7
11.4
231
1396
J20
ICD-10 Finland
Acute bronchitis
1.8
11.4
198
1139
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
11.3
93
394
SPAT1153
SPAT
Removal of sutures
1.4
11.2
707
5521
R06.2
ICD-10 Finland
Wheezing
2.5
11.2
89
369
WZA90
NOMESCO Finland
Other doctors statement
1.5
11.2
426
3017
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.5
11.2
389
2703
K02.1
ICD-10 Finland
Caries of dentine
1.3
11.1
1032
8581
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
11.1
388
2698
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.2
11.0
112
523
A12BA01
ATC
potassium chloride; oral
2.4
11.0
96
416
K05
ICPC
Irregular heartbeat other
3.6
11.0
48
135
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
2.9
11.0
66
234
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.3
11.0
104
471
L17
ICPC
Foot/toe symptom/complaint
1.4
10.9
515
3808
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.9
346
2351
FM1TQ
NOMESCO Finland
Heart perfusion SPECT with low dose CT at rest and with exercise
15.5
10.8
17
11
XG466
NOMESCO Finland
Sleep oxymetry
2.7
10.8
70
260
R2110
NOMESCO Finland
Giving the first information
2.1
10.8
125
620
C01BA03
ATC
disopyramide; systemic
17.9
10.7
16
9
H25.8
ICD-10 Finland
Other senile cataract
1.6
10.7
281
1820
A11
ICPC
Chest pain NOS
1.9
10.7
153
822
I44
ICD-10 Finland
Atrioventricular and left bundle-branch block
60.2
10.6
12
*
I40.9
ICD-10 Finland
Acute myocarditis, unspecified
60.2
10.6
12
*
103
Kela drug reimbursment
Diabetes, insulin-treated
1.4
10.4
570
4328
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
2.6
10.4
74
289
FPJ
NOMESCO Finland
Review and replacement of pacemaker or internal defibrillator device or electrode
+∞
10.4
10
*
FPE36
NOMESCO Finland
Implantation of biventricular cardioverter-defibrillator with ventricular electrodes
+∞
10.4
10
*
4289X
ICD-9 Finland
Heart failure, unspecified
+∞
10.4
10
*
I33.0
ICD-10 Finland
Acute and subacute infective endocarditis
+∞
10.4
10
*
42792
ICD-8 Finland
Symptomatic heart disease, Fibrillatio auricularis
+∞
10.4
10
*
FM1AT
NOMESCO Finland
Percutaneous implantation of aortic valve endoprosthesis
+∞
10.4
10
*
FPG42
NOMESCO Finland
Replacement of electrode(s) in transvenous cardioverter-defibrillator
+∞
10.4
10
*
FFM10
NOMESCO Finland
Occlusion or excision of atrial appendage externally with a closing device
+∞
10.4
10
*
R04.2
ICD-10 Finland
Haemoptysis
2.5
10.4
77
309
JN3AD
NOMESCO Finland
Abdominal CT examination
1.9
10.3
154
839
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
10.3
263
1693
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
10.3
116
568
Z71.8
ICD-10 Finland
Other specified counselling
1.5
10.2
417
2990
J01FA06
ATC
roxithromycin; oral
1.3
10.2
826
6701
Z01.7
ICD-10 Finland
Laboratory examination
1.7
10.1
219
1344
SPAT1310
SPAT
Counselling related to known health issue
1.4
10.1
629
4883
E0000UV
ATC
NA
1.4
10.1
779
6267
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
10.0
1380
12095
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.0
10.0
57
193
I20.0
ICD-10 Finland
Unstable angina
5.3
10.0
29
55
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
9.9
135
715
M25.5
ICD-10 Finland
Pain in joint
1.4
9.8
527
3984
J01FA10
ATC
azithromycin; systemic
1.3
9.8
1065
9007
R60.0
ICD-10 Finland
Localized oedema
1.6
9.8
229
1440
JN4DR
NOMESCO Finland
Whole body metabolic PET with CT
26.1
9.8
13
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.9
9.8
136
723
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.8
9.8
40
107
XCK10
NOMESCO Finland
Photography of fundus of eye
1.7
9.8
227
1426
TKC20
NOMESCO Finland
Catheterisation of bladder
1.9
9.7
149
820
SPAT1211
SPAT
Application of soft bandage
1.8
9.7
180
1059
I20.01
ICD-10 Finland
Unstable angina
2.7
9.7
66
253
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
3.0
9.5
52
174
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.5
269
1778
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.7
9.5
210
1300
K04
ICPC
Palpitations/awareness of heart
2.4
9.5
76
319
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.6
9.5
41
115
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.0
9.5
115
582
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.4
9.5
611
4770
I51.9
ICD-10 Finland
Heart disease, unspecified
100.3
9.4
10
*
E66.01
ICD-10 Finland
Obesity due to excess calories
2.0
9.4
117
599
AC4
HP
MVP
+∞
9.4
9
*
342
Kela drug reimbursment
Dronedarone
+∞
9.4
9
*
4262A
ICD-9 Finland
Conduction disorders, Left bundle branch hemiblock
+∞
9.4
9
*
AB1
HP
AVR mechanical
+∞
9.4
9
*
FPJ12
NOMESCO Finland
Revision of biventricular CRT-P (DDDR) generator
+∞
9.4
9
*
4276B
ICD-9 Finland
Cardiac dysrhythmias, Premature beats[EXTRASYSTOLIA VENTRICULARIS]
+∞
9.4
9
*
42700
ICD-8 Finland
Symptomatic heart disease, Congestive heart failure
+∞
9.4
9
*
I45.6
ICD-10 Finland
Pre-excitation syndrome
+∞
9.4
9
*
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
1.4
9.4
414
3015
FPH96
NOMESCO Finland
Other removal of cardiac pacemaker or cardioverter-defibrillator
21.8
9.3
13
6
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.4
9.3
77
328
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
3.5
9.3
41
117
M54
ICD-10 Finland
Dorsalgia
1.7
9.3
195
1191
XF405
NOMESCO Finland
Symptom ECG
10.7
9.3
17
16
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
9.3
134
725
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
9.5
9.3
18
19
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.1
9.2
105
519
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
9.2
342
2406
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.2
9.1
87
398
I20.9
ICD-10 Finland
Angina pectoris, unspecified
3.9
9.1
36
94
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.0
9.1
116
597
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.9
9.1
132
715
R01.1
ICD-10 Finland
Cardiac murmur, unspecified
3.2
9.0
46
147
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
9.0
269
1800
C08DB01
ATC
diltiazem; oral
2.0
8.9
109
555
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.9
1339
11791
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.5
8.8
296
2031
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.8
489
3714
WZC30
NOMESCO Finland
Teaching
1.5
8.8
271
1828
R00.8
ICD-10 Finland
Other and unspecified abnormalities of heart beat
4.6
8.8
29
64
J45.1
ICD-10 Finland
Nonallergic asthma
1.9
8.8
128
696
A10AE04
ATC
insulin glargine; parenteral
1.7
8.7
166
985
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
8.7
98
480
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.6
8.7
63
250
AR5
HP
Catheter ablation of arrhythmia, target: atrial flutter
50.1
8.7
10
*
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
8.7
261
1748
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.6
885
7389
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.8
8.6
140
788
H26.4
ICD-10 Finland
After-cataract
1.6
8.5
216
1385
FN1CD
NOMESCO Finland
Very extensive CT of coronary arteries
6.9
8.5
20
29
AP3
HP
Catheterization of the right and left side of the heart
27.6
8.5
11
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.3
8.5
41
127
S22.3
ICD-10 Finland
Fracture of rib
1.9
8.4
123
667
FA1AC
NOMESCO Finland
Upper cavography
90.3
8.4
9
*
I30.9
ICD-10 Finland
Acute pericarditis, unspecified
90.3
8.4
9
*
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
8.4
1174
10207
R01AD09
ATC
mometasone; nasal
1.3
8.4
820
6795
AR6
HP
Catheter ablation of arrhythmia, target: atrial fibrillation
+∞
8.3
8
*
PH3AC
NOMESCO Finland
Flebography of internal organs with X-ray
+∞
8.3
8
*
C01BD07
ATC
dronedarone; oral
+∞
8.3
8
*
AR1
HP
Catheter ablation of arrhythmia, target: AV node reentry activation (AVNRT)
+∞
8.3
8
*
FMD22
NOMESCO Finland
Percutaneous transluminal replacement of aortic valve using biological prosthesis
+∞
8.3
8
*
AQ2
HP
Electrophysiological electroanatomical examination
+∞
8.3
8
*
4254A
ICD-9 Finland
Cardiomyopathy, Other primary cardiomyopathies
+∞
8.3
8
*
I34.2
ICD-10 Finland
Nonrheumatic mitral (valve) stenosis
+∞
8.3
8
*
WX930
NOMESCO Finland
Thepapeutic hypothermia
+∞
8.3
8
*
AT4
HP
Physiological pacemaker replacement DDD (R)
+∞
8.3
8
*
C02AC05
ATC
moxonidine; oral
2.1
8.3
89
430
Z01.2
ICD-10 Finland
Dental examination
1.3
8.3
727
5928
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
5.8
8.3
22
38
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
2.7
8.3
54
204
UJF30
NOMESCO Finland
Ileoscopy through colon
1.7
8.2
180
1113
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.1
8.2
85
403
N05CF01
ATC
zopiclone; oral
1.3
8.2
689
5585
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
3.1
8.2
42
136
N03AX16
ATC
pregabalin; oral
1.4
8.2
463
3525
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
7.5
8.1
18
24
TK800
NOMESCO Finland
Hemodialysis
3.3
8.1
39
120
C08CA07
ATC
nisoldipine; oral
3.7
8.1
33
89
J45
ICD-10 Finland
Asthma
1.7
8.1
167
1014
WX740
NOMESCO Finland
Nitrogen oxide therapy
33.4
8.1
10
*
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
8.1
468
3574
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.7
8.1
163
984
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
8.1
879
7384
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
8.0
309
2187
4029A
ICD-9 Finland
Hypertensive heart disease, Unspecified[DECOMPENSATIO CORDIS NON INDICATA (WHO II)]
8.9
8.0
16
18
FN1CC
NOMESCO Finland
Very extensive angiography of heart and/or coronary arteries
3.7
8.0
33
90
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.0
380
2804
SPAT1229
SPAT
Assessment of need for aid
1.7
7.9
165
1004
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.9
1036
8911
A06AC01
ATC
ispaghula (psylla seeds); oral
1.4
7.9
506
3931
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
7.9
275
1908
K30
ICD-10 Finland
Functional dyspepsia
1.6
7.9
189
1199
WX320
NOMESCO Finland
Spinalanesthesy
1.4
7.8
476
3664
A08
ICPC
Swelling
2.1
7.8
80
380
E66.9
ICD-10 Finland
Obesity, unspecified
2.5
7.8
57
228
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
7.8
600
4794
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
7.7
966
8246
Z94.1
ICD-10 Finland
Heart transplant status
45.1
7.7
9
*
FPW96
NOMESCO Finland
Other operation for arhythmia or disturbance of impulse propagation
15.0
7.7
12
8
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
7.7
350
2559
K57
ICD-10 Finland
Diverticular disease of intestine
2.7
7.7
49
182
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.6
707
5796
R05
ICPC
Cough
1.4
7.5
410
3093
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
7.5
477
3699
4130X
ICD-9 Finland
Angina pectoris, Angina decubitus[ANGINA PECTORIS (""""EFFORT ANGINA""""),MÄÄRITTELEMÄT]
2.9
7.5
43
149
N18.8
ICD-10 Finland
Other chronic renal failure
2.6
7.4
52
204
H02AB04
ATC
methylprednisolone; systemic
1.5
7.4
278
1953
I34.01
ICD-10 Finland
Mitral (valve) regurgitation NOS or of specified cause, except rheumatic
80.3
7.4
8
*
N17
ICPC
Vertigo/dizziness
1.5
7.4
222
1487
UKC02
NOMESCO Finland
Cystoscopy
1.4
7.4
354
2610
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.3
7.4
67
301
N30.0
ICD-10 Finland
Acute cystitis
1.5
7.4
248
1706
XG410
NOMESCO Finland
Flow-volume spirometry
2.1
7.4
80
391
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.9
7.3
98
517
FKD10
NOMESCO Finland
Replacement of mitral valve using biological prosthesis
+∞
7.3
7
*
I42.6
ICD-10 Finland
Alcoholic cardiomyopathy
+∞
7.3
7
*
I42.7
ICD-10 Finland
Cardiomyopathy due to drugs and other external agents
+∞
7.3
7
*
4278X
ICD-9 Finland
Cardiac dysrhythmias, Other specified cardiac dysrhythmias[DYSRHYTMIAE CORDIS ALIA DEFINITA]
+∞
7.3
7
*
I46.9
ICD-10 Finland
Cardiac arrest, unspecified
+∞
7.3
7
*
FPJ23
NOMESCO Finland
Revision of biventricular cardioverter-defibrillator with ventricular electrodes
+∞
7.3
7
*
42728
ICD-8 Finland
Symptomatic heart disease, Dissociatio cordis alia
+∞
7.3
7
*
ASX
HP
Other pacemaker insertion
+∞
7.3
7
*
FQA10
NOMESCO Finland
Orthotopic transplantation of heart with bicaval anastomosis
+∞
7.3
7
*
I49
ICD-10 Finland
Other cardiac arrhythmias
4.2
7.3
26
63
Z13.6
ICD-10 Finland
Special screening examination for cardiovascular disorders
4.9
7.3
22
45
R03BA01
ATC
beclometasone; inhalant
1.5
7.2
266
1864
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
7.2
170
1073
C10AA03
ATC
pravastatin; oral
1.7
7.2
152
931
SPAT1260
SPAT
Consultation of another employee
1.4
7.2
332
2434
FP1C5
NOMESCO Finland
Resting ECG, 15 leads
5.4
7.2
20
37
K28
ICPC
Limited function/disability (K)
2.7
7.2
46
170
A02BC05
ATC
esomeprazole; systemic
1.3
7.2
797
6688
FL1AC
NOMESCO Finland
Left cardioangiography
3.3
7.2
34
105
R1420
NOMESCO Finland
Assessment of rehabilitation needs and/or compilation of rehabilitation plan
30.1
7.1
9
*
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
4.4
7.1
24
55
E87.5
ICD-10 Finland
Hyperkalaemia
3.3
7.1
33
100
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.8
7.0
124
721
A41.8
ICD-10 Finland
Other specified sepsis
3.1
7.0
35
113
SPAT1312
SPAT
General health counselling
1.3
7.0
595
4818
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.7
6.9
134
800
AA1
HP
Conventional CABG
2.8
6.9
41
147
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.9
6.9
97
523
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
6.8
580
4690
XF602
NOMESCO Finland
Bloodpressure monitoring
4.4
6.8
23
53
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.1
6.8
75
369
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
6.8
212
1437
GD2SN
NOMESCO Finland
Lung ventilation SPECT
5.7
6.7
18
32
A11CC03
ATC
alfacalcidol; systemic
2.9
6.7
39
137
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.0
6.7
82
421
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
2.0
6.7
84
435
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.0
6.7
35
116
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.7
796
6719
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
2.4
6.7
51
211
WX730
NOMESCO Finland
Conventional respirator
3.3
6.6
31
95
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.6
257
1818
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
2.3
6.6
56
242
A10BH01
ATC
sitagliptin; oral
1.5
6.6
188
1246
A04
ICPC
Weakness/tiredness general
1.5
6.6
217
1484
D82
ICPC
Teeth/gum disease
1.3
6.6
580
4710
Z50.0
ICD-10 Finland
Cardiac rehabilitation
3.6
6.6
27
75
H25.1
ICD-10 Finland
Senile nuclear cataract
1.3
6.6
595
4851
A10BK03
ATC
empagliflozin; oral
1.7
6.5
130
783
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
10.0
6.5
12
12
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
10.0
6.5
12
12
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
1.9
6.5
90
482
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
6.5
181
1193
S01BC05
ATC
ketorolac; ophthalmic
1.9
6.5
88
468
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
6.5
506
4038
R03DA04
ATC
theophylline; systemic, rectal
1.7
6.5
118
693
GD1UN
NOMESCO Finland
Lung circulation SPECT
6.2
6.5
16
26
I31.9
ICD-10 Finland
Disease of pericardium, unspecified
70.0
6.4
7
*
I51.7
ICD-10 Finland
Cardiomegaly
70.0
6.4
7
*
FM1DM
NOMESCO Finland
Heart very extensive MRI examination with 3 Tesla magnet
70.0
6.4
7
*
TFP32
NOMESCO Finland
Cathetric treatmen of cardiac arrythmia
70.0
6.4
7
*
Z95.4
ICD-10 Finland
Presence of other heart-valve replacement
70.0
6.4
7
*
SPAT1081
SPAT
Cardiorespiratory global assessment
1.8
6.4
110
637
82
HP
Single vessel balloon catheter extension
2.5
6.4
46
186
AN4
HP
Balloon angioplasty and drug eluding stent
2.1
6.4
67
322
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.3
6.3
702
5870
SPAT1281
SPAT
Other administrative function
1.6
6.3
143
892
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.3
202
1374
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
1.6
6.3
138
858
PC1BD
NOMESCO Finland
Extensive CT of thoracic aorta
9.3
6.3
12
13
A02BA02
ATC
ranitidine; systemic
1.3
6.3
410
3186
130
Kela drug reimbursment
Malignant tumour
0.6
6.3
89
1467
R03BA05
ATC
fluticasone; inhalant
1.4
6.3
316
2352
FPE10
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial electrode
+∞
6.2
6
*
4270A
ICD-9 Finland
Cardiac dysrhythmias, Paroxysmal supraventricular tachycardia
+∞
6.2
6
*
I47.0
ICD-10 Finland
Re-entry ventricular arrhythmia
+∞
6.2
6
*
4240A
ICD-9 Finland
Other diseases of endocardium, Mitral valve disorders[INSUFFICIENTIA VALVULAE MITRALIS (NON RHEUMATICA)]
+∞
6.2
6
*
5273
FHL
Repair with flap prosthesis or graft
+∞
6.2
6
*
4259X
ICD-9 Finland
Cardiomyopathy, Secondary cardiomyopathy, unspecified
+∞
6.2
6
*
4241B
ICD-9 Finland
Other diseases of endocardium, Aortic valve disorders[STENOSIS VALVULAE AORTAE (NON RHEUMATICA)]
+∞
6.2
6
*
FPJ22
NOMESCO Finland
Revision of cardioverter-defibrillator with atrial and ventricular electrodes
+∞
6.2
6
*
I35
ICD-10 Finland
Nonrheumatic aortic valve disorders
+∞
6.2
6
*
21
HP
Aortic Valve Replacement (AVR)
+∞
6.2
6
*
FPF00
NOMESCO Finland
Implantation of epicardial pacemaker with ventricular electrode
+∞
6.2
6
*
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
+∞
6.2
6
*
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.2
1023
8954
I95.2
ICD-10 Finland
Hypotension due to drugs
4.3
6.2
21
49
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
1.9
6.2
78
406
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
2.0
6.2
71
356
DKW00
NOMESCO Finland
Cauterisation of mucosa of nose
4.1
6.2
22
54
R74
ICPC
Upper respiratory infection acute
1.3
6.2
401
3111
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.6
6.2
174
1150
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.7
6.2
115
683
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
6.2
202
1384
R03BA02
ATC
budesonide; inhalant
1.4
6.2
312
2325
K03.65
ICD-10 Finland
Deposits [accretions] on teeth betel
1.4
6.1
344
2607
C10AA04
ATC
fluvastatin; oral
1.5
6.1
190
1285
N02AX02
ATC
tramadol; systemic, rectal
1.2
6.1
875
7538
K59.0
ICD-10 Finland
Constipation
1.7
6.1
118
709
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.7
6.1
119
713
ZXA10
NOMESCO Finland
Bilateral
1.4
6.1
377
2904
61
HP
Catheterization and pressure measurement of the left side of the heart
3.0
6.1
32
108
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.1
826
7073
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.9
6.0
18
37
C01BA01
ATC
quinidine; oral
10.0
6.0
11
11
XKD00
NOMESCO Finland
Uroflowmetry
1.4
6.0
352
2685
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
3.4
6.0
26
76

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1840
5286
8.06
307.65
5.0
1.8
1648.9
660.8
ng/l
23.58
1664
4317
144
42
36.06
229.32
3.5
1.6
0.8
0.8
nmol/l
0.35
110
18
1528
7761
3.10
189.44
5.5
2.8
52.2
129.5
ng/l
0.66
1205
5571
727
2464
3.62
176.20
2.6
2.2
22.3
23.7
%
1.67
643
2072
758
2646
3.54
175.44
2.5
2.1
2.3
2.3
g/l
0.66
705
2428
523
1419
4.29
174.20
3.1
1.9
278.7
89.4
ng/l
12.79
489
1259
792
2904
3.40
168.83
2.6
2.1
13.1
13.3
umol/l
0.27
742
2657
603
2018
3.52
146.67
35.8
9.9
1.6
1.1
inr
5.64
61
365
1434
8201
2.51
124.11
12.2
4.6
1.4
1.1
inr
15.59
360
2180
801
3692
2.63
106.42
5.0
2.8
519.8
379.3
ng/l
0.32
720
2931
1153
6644
2.24
89.81
6.5
3.3
—
—
—
0
0
197
411
5.08
89.30
2.4
1.7
10.7
11.6
mg/l
0.84
184
374
1314
8004
2.20
88.83
3.3
2.5
151.1
151.2
ug/l
0.01
1191
7257
1792
12772
2.09
75.28
5.6
3.8
6.8
6.8
mmol/l
0.49
1712
11884
923
5151
2.17
75.00
2.4
2.0
2.9
2.9
mg/l
0.30
778
4295
1496
10178
1.99
69.13
6.3
5.0
1.2
1.2
mmol/l
2.47
1347
9038
378
1495
2.76
65.41
2.3
1.9
9.9
5.8
ug/l
1.50
311
1253
2398
19783
2.37
60.78
5.5
4.5
2.0
2.1
mu/l
0.88
2142
17574
751
4144
2.10
60.72
2.1
1.6
1.4
1.4
mg/l
0.21
558
3241
1111
7153
1.91
57.09
5.7
5.5
—
—
—
0
0
1511
10748
1.87
56.65
5.9
5.7
0.2
0.2
e9/l
0.51
1283
9230
1572
11334
1.87
56.34
6.0
6.2
12.1
11.5
umol/l
1.01
1481
10716
1466
10390
1.85
54.99
5.7
5.5
0.0
0.0
e9/l
0.33
1233
8786
945
5829
1.93
54.80
4.8
3.8
—
—
—
0
0
1027
6517
1.90
54.59
2.2
2.0
203.2
202.1
u/l
0.01
957
6047
1456
10329
1.84
54.14
5.7
5.5
0.6
0.6
e9/l
4.79
1232
8724
2531
21691
2.55
53.60
20.5
12.8
23.0
26.0
mg/l
4.74
2140
16942
1483
10608
1.83
53.40
5.9
5.6
1.8
2.0
e9/l
1.07
1261
9130
1386
9713
1.83
53.35
6.1
5.7
2.9
2.9
%
0.21
1283
8916
1390
9761
1.83
53.04
6.4
6.0
8.9
8.8
%
1.05
1289
8997
1555
11320
1.83
52.51
7.1
5.7
1.2
1.2
mmol/l
2.41
1291
9497
590
3120
2.12
52.41
3.7
3.0
0.8
0.8
mmol/l
2.59
542
2868
2646
23272
3.04
51.38
26.3
14.5
139.6
139.7
mmol/l
0.86
2592
22541
2144
17350
1.97
50.78
8.0
7.2
78.3
79.8
u/l
0.75
2012
16132
2647
23340
3.01
50.07
26.6
14.6
4.0
4.0
mmol/l
12.19
2589
22571
1385
9832
1.80
49.91
5.9
5.6
58.7
57.1
%
5.15
1282
9062
1399
9983
1.79
49.34
6.2
5.9
25.6
27.8
%
10.37
1286
9140
1340
9445
1.79
49.25
6.1
5.8
0.7
0.7
%
0.52
1231
8678
2437
20756
2.24
48.74
7.2
6.0
41.1
40.1
mmol/mol
6.04
2206
18839
546
2895
2.10
47.72
2.3
1.8
30.3
28.8
s
7.75
536
2812
1996
16003
1.83
45.75
4.4
3.8
15.1
14.9
pmol/l
4.64
1769
14154
351
1617
2.34
43.19
8.5
5.5
12.1
9.2
mmol/l
8.63
337
1530
1034
6955
1.77
42.95
2.6
2.3
—
—
—
0
0
832
5314
1.80
40.83
2.5
2.3
—
—
—
0
0
1604
12300
1.70
40.50
8.1
9.0
4.3
4.1
e9/l
3.02
1362
10607
1999
16327
1.76
39.61
4.5
3.9
13.6
12.7
mm/h
2.14
1797
14855
283
1237
2.43
39.06
4.5
2.8
5.2
5.1
kpa
0.55
258
1138
2550
22591
2.28
38.68
20.3
12.2
—
—
—
0
0
279
1220
2.43
38.45
4.5
2.8
7.4
7.4
ph
0.77
35
145
2390
20726
1.97
37.58
4.8
4.0
1.3
1.3
mmol/l
2.10
2145
18387
1831
14696
1.69
37.57
5.4
4.5
901.6
2966.5
e6/l
1.72
30
246
2522
22316
2.17
37.20
6.1
5.1
2.5
2.8
mmol/l
46.35
2287
20055
237
982
2.54
36.63
9.0
8.2
23.9
24.2
mmol/l
0.55
221
926
2476
21808
2.07
36.20
5.8
4.8
6.1
6.0
mmol/l
6.19
2209
19455
2451
21533
2.02
35.74
5.4
4.5
1.4
1.5
mmol/l
20.16
2212
19294
438
2363
2.01
35.65
2.4
2.2
1.7
1.7
%
0.33
387
2050
2607
23457
2.38
35.58
12.8
10.2
26.9
25.4
u/l
0.89
2496
22356
454
2496
1.97
34.97
5.6
4.7
1.1
1.0
mmol/l
3.99
409
2302
377
1941
2.09
34.83
6.9
6.6
95.2
96.2
%
2.16
368
1871
830
5508
1.72
34.56
3.0
2.5
4179.0
5818.3
umol/l
0.47
672
4690
1309
9790
1.63
34.13
2.2
2.0
95.9
94.6
pmol/l
0.38
678
4934
2461
21735
2.00
34.08
5.4
4.5
4.3
4.7
mmol/l
55.32
2241
19631
814
5394
1.71
33.97
4.1
3.5
82.7
93.6
%
21.96
797
5274
316
1539
2.19
33.66
9.1
6.9
—
—
—
0
0
212
868
2.56
33.54
1.5
1.5
1.5
1.6
g/l
0.63
174
738
214
894
2.51
32.44
4.5
2.9
—
—
—
0
0
1297
9758
1.61
32.44
4.5
4.3
34.8
35.4
g/l
2.98
1203
8943
403
2180
1.99
32.35
6.9
6.3
5.0
5.1
kpa
1.29
392
2081
401
2166
1.99
32.33
6.9
6.3
0.3
0.9
mmol/l
2.11
349
1664
403
2181
1.99
32.31
6.9
6.2
11.8
12.6
kpa
2.32
389
2084
1868
15356
1.63
32.15
5.0
4.2
—
—
—
0
0
1896
15686
1.63
31.38
5.8
3.3
—
—
—
0
0
2653
24266
2.44
31.13
30.6
19.2
30.4
30.4
pg
0.27
2617
23756
2653
24267
2.44
31.11
30.7
19.2
91.7
91.5
fl
2.76
2617
23758
2653
24268
2.44
31.09
30.8
19.3
4.4
4.5
e12/l
4.58
2578
23297
2653
24271
2.44
31.03
30.8
19.3
7.0
6.7
e9/l
6.08
2578
23301
2652
24261
2.43
30.96
30.8
19.3
239.2
248.9
e9/l
11.17
2587
23398
192
779
2.57
30.92
5.0
2.9
24.8
24.8
mmol/l
0.02
171
713
2653
24277
2.44
30.90
31.0
19.4
133.3
134.9
g/l
6.94
2617
23769
438
2474
1.91
30.86
4.6
4.0
—
—
—
0
0
1627
13119
1.56
28.76
3.4
3.0
53.4
50.7
u/l
0.59
1482
11913
320
1662
2.04
28.62
8.2
5.8
1.3
1.3
mmol/l
0.17
306
1600
806
5564
1.63
27.70
1.6
1.5
20.3
20.8
nmol/l
0.39
669
4633
1059
7820
1.57
27.25
4.4
3.6
146.2
109.5
e6/l
0.24
766
5524
215
984
2.28
26.49
3.2
3.1
4.4
4.5
pmol/l
0.35
189
860
677
4519
1.65
26.41
1.8
1.7
1133.5
1150.3
nmol/l
0.17
481
3307
1306
10153
1.53
26.33
3.9
3.9
—
—
—
0
0
328
1774
1.96
26.06
2.2
2.3
69.2
66.5
e9/l
0.71
261
1337
930
6763
1.56
25.12
3.9
3.1
84.3
90.0
e6/l
0.08
726
5158
915
6674
1.55
24.18
3.8
3.6
7.4
7.4
ph
0.36
207
1204
860
6207
1.55
23.74
3.6
3.0
0.7
0.5
e6/l
1.39
648
4616
240
1201
2.09
23.61
9.1
7.8
0.6
0.7
%
2.04
240
1189
241
1211
2.08
23.44
9.1
7.8
93.8
94.5
%
0.87
241
1206
415
2522
1.76
22.58
7.8
5.8
104.5
104.3
mmol/l
0.43
405
2465
150
629
2.46
22.51
3.4
2.1
339.6
586.9
ug/l
1.17
143
591
990
7450
1.51
22.16
4.4
3.9
10.8
6.1
mg/mmol
1.59
591
4598
315
1773
1.87
22.05
1.9
2.6
65.9
67.0
g/l
1.57
272
1584
107
387
2.83
21.59
3.2
3.4
4.8
5.0
kpa
2.94
102
375
107
387
2.83
21.59
3.2
3.4
2.5
2.4
mmol/l
0.00
67
266
107
389
2.82
21.38
3.2
3.4
8.6
8.5
kpa
0.28
102
376
317
1809
1.85
21.22
7.2
6.9
121.8
121.6
g/l
0.06
310
1740
1160
9079
1.47
21.04
2.3
2.1
78.9
79.6
nmol/l
0.37
987
7907
818
5975
1.52
20.84
3.6
3.0
—
—
—
0
0
107
395
2.78
20.78
2.8
2.3
16.2
16.6
%
0.41
54
213
923
6964
1.48
19.89
3.4
3.2
—
—
—
0
0
934
7069
1.48
19.79
3.5
3.2
289.0
307.0
mg/l
0.05
571
4338
953
7244
1.48
19.74
3.5
3.1
7.0
7.5
mmol/l
3.66
746
5989
168
785
2.21
19.66
1.8
1.6
10.3
36.2
u/ml
—
6
19
104
393
2.71
19.33
3.3
2.9
—
—
—
0
0
442
2854
1.65
18.99
2.1
1.9
—
—
—
0
0
2158
19223
1.51
18.88
21.2
14.4
39.1
39.2
%
0.04
1410
12691
68
206
3.36
18.60
1.2
1.3
29.5
37.2
g/l
5.22
62
193
527
3578
1.58
18.37
3.5
2.9
2.3
2.3
e6/l
0.03
298
1937
730
5326
1.50
18.28
6.6
6.7
—
—
—
0
0
623
4400
1.53
18.19
2.9
2.6
516.7
563.4
mosm/kgh2o
7.16
507
3695
894
6799
1.46
18.12
2.8
2.4
61.4
59.0
u/l
0.37
820
6186
299
1761
1.78
17.94
4.3
2.9
5.8
5.8
kpa
0.58
290
1711
297
1756
1.77
17.57
4.3
2.9
1.6
1.8
mmol/l
0.35
244
1404
56
158
3.60
17.10
1.3
1.3
—
—
—
0
0
113
474
2.44
16.99
3.2
3.1
7.4
7.4
ph
0.62
102
375
647
4676
1.50
16.76
2.9
2.4
6.3
5.0
e6/l
1.32
537
4054
167
836
2.06
16.38
4.5
3.1
24.3
24.1
mmol/l
0.31
149
751
1159
9409
1.39
15.71
12.5
8.7
0.0
0.0
e9/l
0.11
917
7636
268
1590
1.76
15.63
3.4
3.2
95.3
81.1
ng/l
1.90
226
1345
379
2478
1.61
15.29
1.3
1.3
572.4
575.2
titre
0.01
87
541
540
3841
1.50
14.92
3.3
2.8
1.1
1.2
e6/l
0.25
312
2185
213
1200
1.84
14.76
3.0
4.4
—
—
—
0
0
85
334
2.59
14.69
4.4
2.2
—
—
—
0
0
123
571
2.21
14.67
3.7
3.1
—
—
—
0
0
247
1460
1.76
14.58
3.7
2.4
4.7
4.4
kpa
0.78
236
1415
34
76
4.52
14.23
2.9
4.7
—
—
—
0
0
317
2022
1.64
14.09
2.1
2.2
0.2
0.2
g/l
1.05
289
1898
347
2269
1.60
13.94
2.3
2.7
6.8
8.9
umol/l
2.06
294
1988
284
1770
1.67
13.81
1.6
1.5
—
—
—
0
0
31
66
4.74
13.76
4.5
1.8
419.1
1292.0
u/ml
1.73
31
66
251
1518
1.72
13.65
1.7
2.4
—
—
—
0
0
188
1052
1.84
13.32
10.2
8.2
—
—
—
0
0
986
7964
1.36
13.13
3.2
3.5
2.3
2.4
mmol/l
1.64
797
6804
74
288
2.61
13.07
2.2
2.4
—
—
—
0
0
101
461
2.23
12.59
2.4
2.0
128.3
130.1
g/l
0.28
71
324
102
471
2.21
12.37
3.4
2.6
25.0
24.8
mmol/l
0.15
95
412
266
1688
1.64
12.03
2.4
2.2
369.2
372.8
nmol/l
0.10
247
1540
82
349
2.39
12.03
3.2
2.3
—
—
—
0
0
132
685
1.97
11.77
3.3
3.2
0.3
0.2
g/l
0.09
55
270
40
117
3.45
11.66
3.0
2.6
—
—
—
0
0
179
1037
1.77
11.33
1.3
1.2
287.1
247.6
u/ml
0.13
166
951
50
171
2.96
11.30
1.3
1.3
46154.0
104849.4
e6/l
0.85
27
95
121
622
1.99
11.10
2.7
1.7
21.2
20.9
s
0.27
106
557
151
836
1.85
11.09
2.1
1.8
2.2
2.1
ug/l
0.03
133
727
53
190
2.82
11.02
1.4
1.3
1084.0
2555.0
e6/l
2.18
32
133
237
1500
1.63
10.83
1.4
1.4
—
—
—
0
0
334
2289
1.52
10.81
1.9
1.6
—
—
—
0
0
26
59
4.44
10.72
3.9
2.3
—
—
—
0
0
478
3521
1.43
10.71
1.5
1.4
2.6
2.6
g/l
0.15
264
2015
354
2462
1.50
10.68
1.4
1.3
—
—
—
0
0
425
3074
1.45
10.50
1.3
1.2
—
—
—
0
0
99
493
2.04
9.95
1.6
1.5
1.1
1.2
g/l
0.51
90
463
95
473
2.04
9.56
1.6
1.5
0.2
0.2
g/l
0.59
86
446
529
4044
1.38
9.46
1.3
1.2
2.0
1.6
u/ml
0.20
119
1024
165
997
1.70
9.03
1.2
1.3
—
—
—
0
0
279
1928
1.50
8.65
2.4
2.3
37.5
39.2
u/l
0.16
230
1658
50
200
2.53
8.47
4.5
3.0
—
—
—
0
0
444
3369
1.38
8.24
1.3
1.2
26.1
39.5
iu/ml
2.38
111
1058
137
808
1.73
8.21
1.7
2.3
9.6
10.4
g/l
1.58
109
658
143
854
1.71
8.19
3.8
2.0
0.7
0.7
%
0.09
133
814
1077
9239
1.27
8.18
2.3
2.2
—
—
—
0
0
173
1092
1.62
8.02
1.4
1.4
—
—
—
0
0
45
176
2.58
8.00
1.1
1.5
—
—
—
0
0
28
84
3.36
7.93
1.1
1.2
—
—
—
0
0
81
410
2.00
7.86
1.4
1.7
2.4
4.8
iu/l
3.11
25
136
1013
8660
1.26
7.83
5.5
5.4
3.1
3.9
ug/l
0.69
873
7754
118
677
1.78
7.80
1.7
2.2
36.7
38.3
g/l
1.88
90
557
1242
10888
1.25
7.67
4.1
3.7
0.0
0.0
estimate
0.28
225
1899
245
1692
1.49
7.62
1.5
1.5
—
—
—
0
0
174
1116
1.60
7.57
1.9
1.9
1.2
1.4
g/l
1.17
153
1005
114
654
1.77
7.55
2.5
3.4
44.0
125.6
mg/l
0.48
91
548
1221
10703
1.25
7.49
4.1
3.6
0.0
0.0
estimate
0.00
228
1930
557
4434
1.32
7.47
3.1
3.1
2.5
2.5
mmol/l
0.26
474
3886
1225
10751
1.25
7.41
5.5
4.9
0.0
0.0
estimate
0.50
238
1946
113
651
1.77
7.38
2.5
3.4
30.4
57.2
mg/l
1.44
90
546
212
1433
1.52
7.32
2.6
2.6
10.3
10.5
g/l
0.33
196
1296
213
1443
1.51
7.28
1.2
1.2
—
—
—
0
0
155
978
1.62
7.23
2.8
2.8
—
—
—
0
0
39
151
2.60
7.11
1.5
1.3
—
—
—
0
0
68
336
2.05
7.08
2.7
2.6
—
—
—
0
0
301
2195
1.42
7.03
1.9
2.1
125.6
157.1
ug/g
1.08
235
1693
81
430
1.91
6.89
1.2
1.1
—
—
—
0
0
256
1827
1.44
6.74
1.5
1.4
—
—
—
0
0
1901
17626
1.24
6.45
25.3
16.0
13.8
13.7
%
4.12
1871
17166
97
561
1.75
6.30
1.1
1.2
—
—
—
0
0
71
373
1.93
6.26
1.3
1.3
57.6
62.9
mmol/l
0.57
55
297
6
0
+∞
6.25
1.8
0.0
—
—
—
0
0
87
489
1.80
6.23
1.1
1.2
255.0
92.1
titre
—
8
29
410
3205
1.33
6.18
1.3
1.2
11.3
15.0
u/ml
0.48
122
1171
328
2485
1.36
6.09
1.4
1.4
—
—
—
0
0
59
295
2.02
6.00
2.4
2.8
—
—
—
0
0
119
744
1.63
5.82
3.7
4.0
—
—
—
0
0
105
638
1.67
5.74
1.5
1.4
250.9
269.4
ug/g
0.48
62
360
116
725
1.63
5.68
1.6
1.6
—
—
—
0
0
279
2084
1.38
5.67
1.5
1.5
—
—
—
0
0
116
727
1.62
5.63
9.0
8.5
—
—
—
0
0
52
255
2.06
5.60
4.7
4.0
—
—
—
0
0
205
1463
1.43
5.43
3.1
3.4
4.5
4.1
e9/l
0.70
133
1049
258
1918
1.38
5.40
4.4
3.3
1.2
1.2
mmol/l
1.96
237
1645
50
248
2.03
5.24
1.5
1.6
61.3
56.1
%
0.36
32
158
608
5099
1.24
5.20
3.3
3.2
0.8
0.8
ug/l
0.08
439
3576
67
369
1.84
5.18
1.4
1.5
—
—
—
0
0
18
54
3.35
5.16
1.2
1.3
85.5
60.0
%
3.50
12
47
152
1035
1.49
5.14
2.2
1.9
—
—
—
0
0
52
265
1.98
5.07
1.3
1.2
—
—
—
0
0
199
1431
1.42
5.07
1.2
1.2
—
—
—
0
0
236
1748
1.38
5.06
4.0
4.0
0.1
0.1
%
0.50
86
465
170
1198
1.45
4.85
4.9
6.0
24.8
24.5
mmol/l
0.34
163
1108
225
1666
1.38
4.84
3.9
3.8
1.0
0.6
%
0.55
73
364
514
4274
1.25
4.71
4.3
4.5
—
—
—
0
0
72
418
1.74
4.71
1.6
1.4
—
—
—
0
0
160
1123
1.45
4.67
1.1
1.2
85.2
138.4
iu/ml
1.57
49
394
26
103
2.54
4.62
2.8
1.9
573.6
744.2
e6/l
—
8
45
243
1837
1.35
4.60
4.0
3.9
0.9
0.9
%
0.02
89
499
65
370
1.77
4.56
1.5
2.9
31.3
38.1
umol/l
1.01
52
311
79
476
1.68
4.53
1.3
1.2
7.4
2.4
u/ml
—
10
50
220
1648
1.36
4.43
4.1
4.0
0.0
0.1
%
1.02
78
388
77
465
1.67
4.39
2.4
3.6
—
—
—
0
0
139
963
1.47
4.36
1.2
1.2
—
—
—
0
0
58
325
1.80
4.30
1.2
1.4
12.2
12.1
u/l
0.01
44
268
45
239
1.90
3.97
4.6
3.6
64.1
56.2
%
1.36
34
146
101
669
1.53
3.96
3.1
3.5
1.3
1.3
mmol/l
0.06
101
659
72
441
1.65
3.93
1.4
1.6
—
—
—
0
0
25
106
2.37
3.90
1.7
2.4
7.4
7.4
ph
0.04
13
43
37
186
2.00
3.83
1.1
1.1
—
—
—
0
0
24
101
2.39
3.81
1.9
2.3
—
—
—
0
0
229
1769
1.32
3.78
4.8
3.8
—
—
—
0
0
593
5115
1.20
3.75
3.6
3.6
—
—
—
0
0
43
230
1.88
3.73
18.5
5.5
7.7
7.7
mmol/l
0.01
37
186
16
55
2.92
3.73
1.6
2.3
20.6
27.7
%
1.68
16
49
60
357
1.70
3.67
4.1
3.6
1.5
1.3
%
0.22
50
267
48
269
1.80
3.61
1.3
1.5
115.8
117.6
u/ml
—
8
56
691
6069
1.18
3.54
1.6
1.6
1.5
1.4
mmol/l
1.56
563
5054
24
105
2.30
3.52
5.9
3.1
—
—
—
0
0
52
302
1.74
3.48
1.3
1.4
—
—
—
0
0
31
153
2.04
3.40
1.1
1.1
—
—
—
0
0
23
101
2.29
3.35
1.0
1.5
—
—
—
0
0
374
3120
1.23
3.31
1.4
1.3
—
—
—
0
0
26
122
2.14
3.25
1.7
1.7
2.2
1.9
u/field
0.10
16
87
17
66
2.58
3.21
1.1
1.1
—
—
—
0
0
11
33
3.34
3.19
4.9
5.0
—
—
—
0
0
63
398
1.60
3.11
1.2
1.2
—
—
—
0
0
31
159
1.96
3.09
3.0
2.2
0.8
1.1
e9/l
1.26
21
101
30
154
1.96
2.99
3.9
2.4
—
—
—
0
0
19
81
2.35
2.98
1.3
1.2
—
—
—
0
0
44
256
1.73
2.97
1.5
1.6
0.8
0.8
g/l
0.01
33
193
83
564
1.49
2.97
3.4
3.7
4.0
3.8
mmol/l
1.25
77
526
71
469
1.53
2.91
2.5
2.7
1.8
1.5
mg/l
2.88
66
426
586
5158
1.17
2.88
1.8
1.7
27586673.6
26998523.0
pmol/l
0.01
464
4204
53
328
1.63
2.87
1.2
1.3
29.4
29.9
u/l
0.02
41
275
23
109
2.12
2.84
3.0
3.8
—
—
—
0
0
27
137
1.98
2.80
2.6
1.8
10.5
10.6
%
0.03
27
137
157
1205
1.32
2.79
2.6
2.4
—
—
—
0
0
22
104
2.12
2.74
1.7
2.0
—
—
—
0
0
38
219
1.74
2.68
1.2
1.2
—
—
—
0
0
67
446
1.51
2.68
1.7
1.7
45.6
42.8
nmol/l
0.25
61
433
47
288
1.64
2.66
1.0
1.1
—
—
—
0
0
25
126
1.99
2.65
2.1
2.1
16.5
14.4
%
0.28
14
49
77
530
1.47
2.62
1.5
1.6
28829.7
11728.7
e6/l
1.24
54
374
25
127
1.98
2.60
2.2
2.2
70.3
70.9
%
0.07
25
120
654
5850
1.15
2.59
4.5
4.0
0.0
0.0
estimate
0.88
219
1897
230
1875
1.25
2.56
3.5
3.4
—
—
—
0
0
12
44
2.73
2.54
1.0
1.0
—
—
—
0
0
12
44
2.73
2.54
1.1
1.1
—
—
—
0
0
14
56
2.51
2.53
1.5
2.3
11.9
10.9
%
0.11
14
48
26
136
1.92
2.50
2.1
2.3
—
—
—
0
0
319
2698
1.21
2.49
3.7
4.3
5.8
23.2
ug/l
3.71
254
2225
43
265
1.63
2.41
1.0
1.1
—
—
—
0
0
41
250
1.65
2.40
1.2
1.3
—
—
—
0
0
25
132
1.90
2.35
1.1
1.2
—
—
—
0
0
23
118
1.96
2.35
3.0
3.7
—
—
—
0
0
42
260
1.62
2.32
1.5
1.4
106.0
61.7
mu/l
0.30
37
232
39
237
1.65
2.32
1.3
1.3
—
—
nmol/l
—
0
0
31
177
1.76
2.30
1.5
1.9
255.9
2282.0
u/l
—
10
64
51
332
1.55
2.30
1.3
1.3
166.5
222.6
miu/ml
0.45
18
134
13
53
2.46
2.27
1.4
1.7
—
—
—
0
0
6
13
4.62
2.27
1.3
1.8
—
—
—
0
0
1862
17870
1.12
2.24
25.9
17.1
331.1
332.2
g/l
5.96
1850
17705
5
9
5.56
2.21
1.0
1.0
3.5
9.2
mg/l
—
5
9
62
426
1.47
2.18
1.7
1.6
1.2
0.8
nmol/l
2.53
49
350
42
266
1.59
2.14
1.1
1.2
273.7
277.6
u/ml
0.04
26
159
12
49
2.45
2.10
1.5
1.8
—
—
—
0
0
34
206
1.66
2.07
1.1
1.1
—
—
—
0
0
31
184
1.69
2.04
1.2
1.2
—
—
—
0
0
27
154
1.76
2.04
1.4
1.3
3.1
3.1
g/l
0.04
19
105
27
154
1.76
2.04
1.4
1.3
0.4
0.4
g/l
0.07
20
105
27
154
1.76
2.04
1.4
1.3
6.7
6.6
g/l
0.02
19
106
93
697
1.35
2.02
1.3
1.2
0.1
1.0
u/ml
—
10
67
17
83
2.05
2.01
1.1
1.2
1.1
1.1
ratio
—
7
30
37
232
1.60
1.99
2.1
1.5
—
—
—
0
0
40
256
1.57
1.98
2.4
2.5
—
—
—
0
0
245
2074
1.20
1.94
1.6
1.6
—
—
—
0
0
615
5583
1.13
1.93
1.3
1.3
—
—
—
0
0
22
120
1.84
1.92
1.9
1.7
—
—
—
0
0
182
1498
1.23
1.92
3.0
3.1
—
—
—
0
0
74
540
1.38
1.91
3.0
3.3
32.6
922.3
u/ml
1.17
67
493
70
508
1.39
1.88
2.9
2.2
—
—
—
0
0
26
151
1.73
1.87
1.5
1.3
—
—
—
0
0
34
214
1.60
1.82
2.4
1.9
—
—
—
0
0
7
23
3.05
1.80
1.9
1.8
16.2
18.7
umol/l
—
7
23
53
370
1.44
1.77
3.1
3.3
60.6
57.6
%
0.96
53
370
44
296
1.49
1.77
1.7
1.2
—
—
—
0
0
46
313
1.48
1.76
1.3
1.3
—
—
—
0
0
16
81
1.98
1.74
1.1
1.1
—
—
—
0
0
28
170
1.65
1.73
2.5
2.2
—
—
—
0
0
34
218
1.57
1.70
1.2
1.2
—
—
—
0
0
37
242
1.54
1.70
1.4
1.2
—
—
—
0
0
11
49
2.25
1.63
1.5
1.2
—
—
—
0
0
10
44
2.28
1.53
2.5
1.8
—
—
—
0
0
31
201
1.55
1.51
1.7
2.0
1.9
2.2
u/field
0.12
15
68
35
234
1.50
1.49
1.7
1.5
—
—
—
0
0
27
170
1.59
1.49
1.7
1.8
—
—
—
0
0
9
38
2.37
1.45
1.0
1.1
—
—
—
0
0
13
66
1.97
1.43
1.8
1.2
—
—
—
0
0
14
74
1.90
1.39
1.2
1.4
—
—
—
0
0
11
53
2.08
1.38
1.0
1.0
—
—
—
0
0
23
143
1.61
1.35
1.3
1.1
—
—
—
0
0
50
673
0.74
1.34
5.6
4.3
—
—
—
0
0
104
845
1.24
1.32
3.3
4.4
0.8
0.9
%
0.66
99
797
13
69
1.89
1.28
26.4
24.8
91.4
114.6
ug/l
—
8
62
35
243
1.45
1.27
1.4
1.3
207.2
264.9
pmol/l
0.99
27
191
40
285
1.41
1.27
1.1
1.1
—
—
—
0
0
247
2177
1.15
1.26
1.4
1.3
—
—
—
0
0
19
115
1.66
1.24
1.1
1.0
—
—
—
0
0
25
164
1.53
1.20
1.2
1.8
7.4
6.5
mmol/l
1.15
17
108
46
340
1.36
1.20
1.2
1.4
—
—
—
0
0
0
34
0.00
1.16
0.0
4.1
—
43.5
—
0
28
57
439
1.30
1.14
1.4
1.4
—
—
—
0
0
11
58
1.90
1.12
2.2
1.9
—
—
—
0
0
19
119
1.60
1.11
1.0
1.0
—
—
—
0
0
19
119
1.60
1.11
1.1
1.1
—
—
—
0
0
8
41
1.95
1.08
2.5
1.7
—
—
—
0
0
16
97
1.65
1.06
1.9
1.6
—
—
—
0
0
34
245
1.39
1.05
1.4
1.2
2.8
3.5
u/ml
0.38
18
102
179
1566
1.15
1.05
2.3
2.1
11.1
12.4
nmol/l
0.96
158
1360
39
288
1.36
1.05
5.7
4.6
355.5
354.0
umol/l
0.02
34
256
30
212
1.42
1.03
1.5
1.3
13944.0
105259.7
e6/l
1.32
21
149
18
114
1.58
1.02
2.0
1.6
—
—
—
0
0
14
83
1.69
1.01
1.4
1.3
18.0
28.0
umol/l
1.01
14
77
602
5649
1.08
0.99
4.3
3.4
—
—
—
0
0
72
584
1.24
0.98
3.6
5.5
1.5
1.3
mmol/l
0.41
66
516
14
84
1.67
0.97
2.7
2.6
1872.9
1852.3
ml
0.03
14
71
26
182
1.43
0.96
1.5
1.4
—
—
—
0
0
26
182
1.43
0.96
1.5
1.4
—
—
—
0
0
26
182
1.43
0.96
1.5
1.4
—
—
—
0
0
26
182
1.43
0.96
1.5
1.4
—
—
—
0
0
73
889
0.82
0.95
1.4
1.5
—
—
—
0
0
6
27
2.22
0.93
5.3
6.0
—
—
—
0
0
9
52
1.73
0.92
1.1
1.3
—
—
—
0
0
66
540
1.23
0.86
2.6
2.3
235.5
86.5
ug/min
0.82
40
313
20
136
1.47
0.86
1.0
1.3
0.2
1.5
u/ml
1.02
12
64
17
112
1.52
0.84
1.1
1.4
—
—
—
0
0
6
31
1.94
0.84
3.7
1.4
78.2
127.9
ng/l
—
6
31
30
222
1.35
0.83
4.7
3.2
152.4
27.1
mg/l
0.92
23
164
16
106
1.51
0.78
1.9
2.7
41.4
37.7
%
—
5
40
33
251
1.32
0.78
1.2
1.1
—
13.7
—
0
10
27
199
1.36
0.78
1.0
1.0
2.2
3.7
u/ml
0.48
14
90
84
715
1.18
0.75
1.2
1.1
—
1.0
—
0
11
11
67
1.64
0.75
1.3
2.8
—
—
—
0
0
26
192
1.36
0.75
1.7
2.2
—
—
—
0
0
59
711
0.83
0.74
1.7
1.7
—
—
—
0
0
111
1268
0.87
0.74
1.3
1.4
—
—
—
0
0
26
193
1.35
0.73
1.0
1.0
0.7
1.5
u/ml
0.42
13
74
35
272
1.29
0.72
2.7
1.9
—
—
—
0
0
63
527
1.20
0.70
1.0
1.0
—
—
—
0
0
28
212
1.32
0.70
1.2
1.2
—
23.9
—
0
11
15
101
1.49
0.70
1.1
1.1
—
—
—
0
0
7
41
1.71
0.70
1.1
1.5
—
—
—
0
0
10
61
1.64
0.68
1.5
1.6
—
—
—
0
0
9
59
1.53
0.68
1.1
1.1
—
—
—
0
0
9
59
1.53
0.68
1.1
1.1
—
—
—
0
0
9
59
1.53
0.68
1.1
1.1
—
—
—
0
0
7
44
1.59
0.65
1.1
1.0
—
—
—
0
0
32
251
1.28
0.64
1.6
1.3
—
—
—
0
0
8
49
1.63
0.62
1.3
2.0
—
—
—
0
0
26
200
1.30
0.60
1.4
1.5
27.1
29.6
%
0.13
15
122
20
148
1.35
0.59
1.1
1.2
—
—
—
0
0
20
148
1.35
0.59
1.3
1.6
1443.1
1839.8
ml
—
8
34
43
355
1.21
0.57
1.6
1.5
—
—
—
0
0
6
36
1.67
0.56
1.2
1.1
—
—
—
0
0
6
36
1.67
0.56
1.0
1.3
—
—
—
0
0
11
73
1.51
0.56
2.9
2.0
—
—
—
0
0
8
55
1.46
0.56
1.1
1.5
—
—
—
0
0
29
230
1.26
0.55
1.3
1.4
—
—
—
0
0
6
38
1.58
0.54
1.0
1.4
—
—
—
0
0
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
498
4758
1.06
0.52
4.5
4.1
1.0
1.0
kg/l
0.09
81
750
9
134
0.67
0.51
1.1
1.1
—
8.3
—
0
29
51
434
1.18
0.51
1.3
1.4
39.7
34.7
iu/l
0.50
41
370
53
618
0.85
0.51
1.2
1.2
—
—
—
0
0
25
199
1.26
0.48
1.6
1.3
1.5
1.4
nmol/l
0.05
19
174
7
47
1.49
0.47
1.1
1.0
—
—
—
0
0
21
164
1.28
0.46
2.0
1.9
—
1.0
—
0
10
6
92
0.65
0.42
1.2
1.3
—
—
—
0
0
5
33
1.52
0.41
1.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.6
1.0
15.8
15.7
umol/l
—
5
28
8
61
1.31
0.39
3.3
1.9
104.3
147.5
nmol/l
—
8
54
5
35
1.43
0.39
1.0
1.1
—
181.7
—
0
6
9
68
1.32
0.37
1.3
1.1
—
—
—
0
0
8
113
0.71
0.37
5.5
7.0
—
—
—
0
0
22
182
1.21
0.33
1.3
1.2
2.1
1.9
mmol/l
0.35
22
169
15
119
1.26
0.31
2.3
1.3
1.7
1.1
nmol/l
—
10
90
36
411
0.87
0.31
4.2
4.2
19.8
40.3
u/ml
2.15
36
402
7
55
1.27
0.30
1.1
1.7
—
—
—
0
0
8
63
1.27
0.27
2.1
1.5
—
—
—
0
0
16
131
1.22
0.27
1.6
1.1
—
—
—
0
0
8
67
1.19
0.26
1.0
1.1
140.4
222.6
iu/ml
—
8
67
15
124
1.21
0.24
1.7
1.7
—
—
—
0
0
5
38
1.32
0.23
3.8
3.1
—
—
—
0
0
5
38
1.32
0.23
1.2
1.2
—
—
—
0
0
18
153
1.18
0.22
1.0
1.0
289.4
281.1
mg/l
0.25
18
137
5
41
1.22
0.22
1.0
1.2
—
—
—
0
0
5
42
1.19
0.21
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.1
—
0
6
0
11
0.00
0.21
0.0
1.1
—
0.2
—
0
6
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
5.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
96
907
1.06
0.20
2.3
3.4
251.8
2746.8
u/ml
1.15
83
776
0
14
0.00
0.20
0.0
1.6
—
1.8
—
0
9
70
656
1.07
0.19
1.0
1.0
—
—
—
0
0
24
213
1.13
0.18
1.2
1.4
284.7
279.8
mosm/kgh2o
0.68
19
158
106
1113
0.95
0.18
1.3
1.3
—
—
—
0
0
44
476
0.92
0.17
1.4
1.4
14.3
16.7
e6/l
0.08
36
368
44
476
0.92
0.17
1.5
1.5
248.4
897.2
e6/l
1.27
38
385
5
67
0.75
0.17
1.0
1.1
2085.0
1708.6
miu/ml
—
5
67
23
205
1.12
0.17
1.5
1.6
—
—
—
0
0
7
89
0.79
0.14
1.0
1.3
—
—
—
0
0
51
542
0.94
0.14
6.5
3.3
23.2
26.9
mg/l
0.43
27
333
16
142
1.13
0.12
1.0
1.0
3.3
2.4
u/ml
—
9
54
687
6950
0.98
0.12
3.5
3.1
—
—
—
0
0
25
229
1.09
0.12
1.2
1.1
0.6
1.7
u/ml
—
9
88
25
271
0.92
0.11
2.0
1.6
—
—
—
0
0
51
537
0.95
0.11
1.3
1.3
—
—
—
0
0
54
517
1.05
0.09
3.9
2.5
1.5
1.6
mmol/l
0.27
54
503
14
155
0.90
0.09
1.1
1.0
3.3
2.5
u/ml
—
5
61
14
126
1.11
0.09
1.0
1.0
0.7
0.5
u/ml
—
6
34
52
498
1.04
0.08
4.0
2.6
7.8
7.6
mmol/l
0.29
52
485
19
206
0.92
0.08
1.2
1.0
—
—
—
0
0
110
1071
1.03
0.08
3.3
3.8
46.5
72.7
u/ml
1.05
105
1032
22
205
1.07
0.07
2.1
1.4
—
—
—
0
0
19
177
1.07
0.06
2.2
2.2
634.5
600.2
ml
0.11
13
104
9
103
0.87
0.06
1.4
1.2
138.7
141.5
nmol/l
—
9
103
26
274
0.95
0.06
2.0
1.6
—
—
—
0
0
126
1237
1.02
0.06
4.2
3.5
—
—
—
0
0
30
286
1.05
0.06
1.3
1.3
—
—
—
0
0
24
253
0.95
0.05
2.0
1.6
—
—
—
0
0
26
273
0.95
0.05
2.0
1.6
—
—
—
0
0
23
218
1.06
0.05
1.0
1.2
—
—
—
0
0
26
272
0.96
0.04
2.0
1.6
—
—
—
0
0
21
220
0.95
0.03
1.0
1.1
—
—
—
0
0
18
171
1.05
0.03
1.1
1.0
1.3
2.4
u/ml
—
5
44
11
102
1.08
0.03
1.5
1.2
—
—
—
0
0
21
218
0.96
0.02
1.0
1.1
—
—
—
0
0
23
236
0.97
0.00
1.4
1.1
—
—
—
0
0
54
534
1.01
0.00
1.1
1.1
—
—
—
0
0
14
138
1.01
0.00
1.2
1.4
—
—
—
0
0
16
164
0.98
0.00
1.3
1.1
—
—
—
0
0
41
411
1.00
0.00
2.0
1.6
—
—
—
0
0
17
167
1.02
0.00
3.1
2.2
—
—
—
0
0
15
147
1.02
0.00
1.4
1.4
0.9
1.1
promille
—
8
113
71
711
1.00
0.00
1.4
1.5
—
—
—
0
0
14
139
1.01
0.00
1.1
1.1
—
—
—
0
0
10
99
1.01
0.00
1.2
1.3
6.0
6.3
mmol/l
—
10
90
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
1.2
—
0
7
0
7
0.00
0.00
0.0
5.0
—
35.3
—
0
7
0
5
0.00
0.00
0.0
1.2
—
1270.0
—
0
5
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
46.1
—
0
5
6
63
0.95
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
4.2
—
0
7
6
66
0.91
0.00
1.8
1.4
1.8
2.1
umol/l
—
6
59
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
7
70
1.00
0.00
1.1
1.2
—
19.3
%
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint I9_LBBB and mortality.

Females

Parameter HR [95% CI] p-value
I9_LBBB 1.485 [1.31, 1.69] < 0.001
Birth year 0.991 [0.98, 1.0] 0.049

During the follow-up period (1.1.1998 — 31.12.2019), 1404 out of 6319 females with I9_LBBB died.

Males

Parameter HR [95% CI] p-value
I9_LBBB 1.602 [1.39, 1.85] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1722 out of 5910 males with I9_LBBB died.

Mortality risk

Mortality risk for people of age

years, who have I9_LBBB.

N-year risk Females Males
1 0.122% 0.242%
5 0.711% 1.661%
10 1.908% 4.146%
15 3.579% 8.024%
20 6.132% 13.259%

Relationships between endpoints

Index endpoint: I9_LBBB – Left bundle-branch block

GWS hits: 5

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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