All dysplastic lesions of the vulva

N14_VULVAL_DYSPLASIA_ALL

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1609

4. Check minimum number of events

None

1609

5. Include endpoints

None

1609

6. Filter based on genotype QC (FinnGen only)

1609

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 9508 9508 -
Only index persons 8975 8975 -
Unadjusted period prevalence (%)
Whole population 0.27 0.27 -
Only index persons 0.33 0.33 -
Median age at first event (years)
Whole population - 38.96 -
Only index persons - 38.45 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1609 1609 -
Unadjusted period prevalence (%) 0.55 0.55 -
Median age at first event (years) 40.58 40.58 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1414
Matched controls
14141
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
50.4
323.0
534
168
N90.0
ICD-10 Finland
Mild vulvar dysplasia
+∞
323.0
380
*
0781C
ICD-9 Finland
Other diseases due to viruses and Chlamydiae, Viral warts[CONDYLOMA ACCUMINATUM]
+∞
323.0
587
*
ULA02
NOMESCO Finland
Kolposcopy
12.0
323.0
739
1182
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
+∞
287.6
266
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
+∞
254.0
236
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
6.1
176.0
593
1489
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
47.5
170.2
208
51
8474
FHL
Coagulation, excision, or biopsy of local change (eg, condyloma, tumor) in operating room or anesthesia
154.4
168.6
176
13
8325
FHL
Coagulation, cryo or laser in anesthesia or operating room
266.8
143.0
144
6
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
+∞
140.0
132
*
LFC00
NOMESCO Finland
Partial excision of vulva
218.3
117.5
120
6
LEB00
NOMESCO Finland
Biopsy of vagina
15.3
116.7
200
151
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
112.0
106
*
8411
FHL
Local change laser, coagulation, biopsy or removal
146.0
102.6
108
8
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
46.0
102.5
126
30
A63.0
ICD-10 Finland
Anogenital (venereal) warts
9.2
92.6
204
253
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
5.3
91.7
318
740
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
4.2
88.7
398
1202
D06BB10
ATC
imiquimod; topical
8.1
81.8
195
273
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
9.0
76.4
170
212
N89.0
ICD-10 Finland
Mild vaginal dysplasia
39.8
57.2
72
19
D06BB04
ATC
podophyllotoxin; topical
5.5
56.7
180
366
LDA10
NOMESCO Finland
Curettage of cervix uteri
4.6
48.9
184
447
8326
FHL
Batch conization
22.6
47.4
69
32
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.3
47.0
686
4119
D07AD01
ATC
clobetasol; topical
2.9
46.2
341
1412
N87.0
ICD-10 Finland
Mild cervical dysplasia
5.9
44.2
130
239
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
+∞
41.9
40
*
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
45.1
39.3
48
11
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
20.4
38.1
57
29
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
4.0
38.0
164
451
N90.9
ICD-10 Finland
Noninflammatory disorder of vulva and perineum, unspecified
15.1
34.7
58
40
J02AC01
ATC
fluconazole; systemic
1.9
30.3
825
5970
C51.01
ICD-10 Finland
Squamous cell carcinoma of the labium majus
308.7
29.9
30
*
N90.4
ICD-10 Finland
Leukoplakia of vulva
16.7
29.5
47
29
1390
FHL
Colposcopy
67.4
29.0
33
5
8070/3-C51.9
ICD-O-3
Squamous cell carcinoma, NOS, of vulva, NOS
105.6
28.8
31
*
C51.11
ICD-10 Finland
Squamous cell carcinoma of the labium minus
102.1
27.7
30
*
6221A
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI LEVIS]
29.9
26.4
35
12
N90.8
ICD-10 Finland
Other specified noninflammatory disorders of vulva and perineum
10.3
25.9
51
51
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
+∞
24.0
23
*
P01AB01
ATC
metronidazole; oral, rectal
1.8
24.0
695
4968
8111
FHL
Taking a biopsy from the mouth of the uterus at the operating room or under anesthesia (vulvabiopsia 8474, vaginabiopsia 8411)
27.2
23.6
32
12
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
37.0
23.0
29
8
N87.1
ICD-10 Finland
Moderate cervical dysplasia
4.3
22.9
87
212
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
4.2
21.3
82
202
6221B
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI MODERATA]
21.9
19.5
28
13
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
22.9
19.1
27
12
WX002
NOMESCO Finland
Sedation and analgesia
2.0
19.0
284
1592
N76.6
ICD-10 Finland
Ulceration of vulva
9.3
18.9
39
43
8070/2-C51.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vulva, NOS
192.4
18.6
19
*
G01AA10
ATC
clindamycin; vaginal
1.8
18.3
354
2170
J01MA02
ATC
ciprofloxacin; systemic
1.7
17.9
507
3496
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
17.8
180
850
8113
FHL
Fractional scraping
2.6
17.7
135
551
N02AX02
ATC
tramadol; systemic, rectal
1.6
17.0
570
4108
G01AF01
ATC
metronidazole; vaginal
2.0
16.8
248
1376
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
5.0
16.6
53
109
7950A
ICD-9 Finland
Nonspecific abnormal histological and immunological findings, Nonspecific abnormal Papanicolaou smear of cervix
30.4
16.1
21
7
A02BC02
ATC
pantoprazole; systemic
1.6
15.6
913
7528
WX320
NOMESCO Finland
Spinalanesthesy
1.8
15.6
319
1977
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
5.5
15.3
45
84
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
15.3
396
2640
127
Kela drug reimbursment
Transplant complication
7.4
15.0
35
48
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.9
14.8
222
1233
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.7
14.8
104
405
LFD10
NOMESCO Finland
Vulvectomy and excision of regional lymph nodes
80.9
14.6
16
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.2
14.6
150
714
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
4.2
14.4
54
131
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
3.6
14.1
64
185
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
14.0
641
4923
8339
FHL
Other measure in this category
12.2
13.6
24
20
L04AA06
ATC
mycophenolic acid; systemic
5.4
13.5
40
76
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.7
13.5
45
98
6350C
ICD-9 Finland
Legally induced abortion, Complicated by genital tract and pelvic infection[ABORTUS PROV LEGAL SINE COMPL,SOSIAALISET SYYT]
2.2
13.2
135
638
J01FF01
ATC
clindamycin; systemic
1.6
13.1
380
2590
N03AX16
ATC
pregabalin; oral
1.7
13.1
344
2282
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
13.1
511
3762
8112
FHL
Scraping the cervix
50.5
12.9
15
*
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
3.3
12.7
64
201
C51.81
ICD-10 Finland
Squamous cell carcinoma of the vulva
70.5
12.6
14
*
2333B
ICD-9 Finland
Carcinoma in situ of breast and genito-urinary system, Other and unspecified female genital organs[CARCINOMA IN SITU VULVAE]
+∞
12.5
12
*
ZXC10
NOMESCO Finland
Use of laser
4.4
12.5
45
106
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
12.4
360
2453
T89
ICPC
Diabetes insulin dependent
3.3
12.3
62
195
TPH04
NOMESCO Finland
Cathetrisation of vein
1.7
12.2
268
1686
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.1
12.1
67
225
L29.2
ICD-10 Finland
Pruritus vulvae
4.4
12.1
43
100
ZXC00
NOMESCO Finland
Use of diathermy
8.3
12.1
26
32
6221C
ICD-9 Finland
Noninflammatory disorders of cervix, Dysplasia of cervix (uteri)[DYSPLASIA CERVICIS UTERI GRAVIS]
18.2
12.1
18
10
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
12.0
331
2221
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
11.9
521
3917
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.1
11.8
141
713
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
9.7
11.7
23
24
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
11.7
422
3028
LCA06
NOMESCO Finland
Biopsy of endometrium
1.7
11.7
262
1657
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
11.7
452
3298
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.0
11.7
166
900
C51.9
ICD-10 Finland
Malignant neoplasm: Vulva, unspecified
65.5
11.6
13
*
7020X
ICD-9 Finland
Other dermatoses, Actinic keratosis[DERMATOSES PRAECANCEROSAE ALIAE]
+∞
11.5
11
*
D07AC01
ATC
betamethasone; topical
1.5
11.4
456
3353
A10AA01
ATC
NA
3.6
11.2
49
138
E0000UV
ATC
NA
1.5
11.1
554
4266
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
11.0
392
2799
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
5.0
10.7
33
67
B01AB10
ATC
tinzaparin; parenteral
2.3
10.5
100
460
ZXA00
NOMESCO Finland
Right side
1.6
10.5
338
2352
LFD00
NOMESCO Finland
Vulvectomy
110.8
10.4
11
*
C03CA01
ATC
furosemide; systemic
1.6
10.4
279
1848
A10AE04
ATC
insulin glargine; parenteral
2.2
10.4
100
463
A10AA02
ATC
NA
3.1
10.3
54
176
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.1
10.2
54
178
A06AC01
ATC
ispaghula (psylla seeds); oral
1.6
10.2
340
2383
R4110
NOMESCO Finland
Physiotherapy
1.6
10.1
338
2370
J01EA01
ATC
trimethoprim; systemic
1.5
10.0
418
3081
UKC02
NOMESCO Finland
Cystoscopy
1.9
10.0
145
793
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
9.9
359
2563
G01AF04
ATC
miconazole; vaginal
2.0
9.9
123
636
PJD55
NOMESCO Finland
Block dissection of inguinal lymph nodes
20.2
9.8
14
7
N02BE01
ATC
paracetamol; systemic, rectal
1.6
9.7
1199
10988
J01DB01
ATC
cefalexin; oral
1.5
9.7
1134
10254
UJF32
NOMESCO Finland
Coloscopy
1.5
9.6
328
2306
TLC02
NOMESCO Finland
Simple extraction of IUD
2.2
9.5
100
480
8542/3-C51.9
ICD-O-3
Paget disease, extramammary of vulva, NOS
100.7
9.4
10
*
LX1XE
NOMESCO Finland
Other gynecological ultrasound examination
2.7
9.4
63
240
LWA00
NOMESCO Finland
Repair of wound dehiscence in gynaecological surgery
21.8
9.4
13
6
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
4.4
9.2
32
74
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.5
9.2
31
70
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.7
9.2
215
1370
TAC99
NOMESCO Finland
Other blockade for chronic pain
5.9
9.1
24
41
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
9.0
796
6750
LFE10
NOMESCO Finland
Plastic repair of vulva
9.1
9.0
18
20
J05AB11
ATC
valaciclovir; oral
1.7
9.0
195
1214
Z94.0
ICD-10 Finland
Kidney transplant status
6.6
9.0
22
34
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
8.9
124
669
H04AA01
ATC
glucagon; nasal, parenteral
3.6
8.9
38
107
N06AB06
ATC
sertraline; oral
1.8
8.9
168
1006
J01MA12
ATC
levofloxacin; systemic
1.7
8.7
208
1335
R2110
NOMESCO Finland
Giving the first information
1.9
8.7
126
690
LFC96
NOMESCO Finland
Other partial excision of vulva or perineum
50.3
8.7
10
*
C51.00
ICD-10 Finland
Malignant tumor of the labium majus without histology
50.3
8.7
10
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
8.7
347
2520
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
5.3
8.6
25
48
J05AB01
ATC
aciclovir; systemic
1.5
8.6
315
2243
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
8.6
196
1240
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
8.6
459
3539
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.2
8.6
87
413
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
16.4
8.6
13
8
N94.1
ICD-10 Finland
Dyspareunia
4.4
8.4
29
67
WX110
NOMESCO Finland
Local anesthesy
1.4
8.4
940
8267
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
8.4
157
937
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
6.7
8.4
20
30
8070/3-C51.1
ICD-O-3
Squamous cell carcinoma, NOS, of labium minus
+∞
8.3
8
*
J02AC02
ATC
itraconazole; systemic
1.5
8.3
273
1896
J01DA01
ATC
[U] cefalexin; systemic
1.4
8.3
893
7788
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
5.5
8.3
23
42
N01BB02
ATC
lidocaine; parenteral
4.8
8.3
26
55
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
8.2
292
2066
J01AA02
ATC
doxycycline; systemic
1.5
8.2
1101
9989
TQW99
NOMESCO Finland
Other minor procedure on skin
2.4
8.2
67
288
8513
FHL
Softening of cervix with abortifacient or laminars and associated surgical emptying of the uterus
2.5
8.2
63
262
Y83.8
ICD-10 Finland
Other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.9
8.2
47
164
H3603, E103
ICD-10 Finland
NA
5.7
8.1
22
39
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.0
8.1
104
545
ZX120
NOMESCO Finland
Intravenous
1.9
8.1
123
684
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
8.0
103
539
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
8.0
53
203
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
8.0
168
1036
A11CC03
ATC
alfacalcidol; systemic
3.6
8.0
34
96
L04AX01
ATC
azathioprine; systemic
2.4
7.9
67
292
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
13.1
7.9
13
10
N81.6
ICD-10 Finland
Rectocele
1.9
7.8
119
662
M03BX02
ATC
tizanidine; oral
1.4
7.8
903
7925
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.8
7.8
140
827
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.7
521
4172
N76.3
ICD-10 Finland
Subacute and chronic vulvitis
5.1
7.7
23
46
M54.5
ICD-10 Finland
Low back pain
1.4
7.7
456
3567
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
7.7
712
6016
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.0
7.7
20
34
ZXA10
NOMESCO Finland
Bilateral
1.6
7.7
231
1568
M01AE02
ATC
naproxen; oral, rectal
1.4
7.6
785
6746
A02BC05
ATC
esomeprazole; systemic
1.4
7.6
548
4436
B97.7
ICD-10 Finland
Papillomavirus as the cause of diseases classified to other chapters
11.9
7.6
13
11
C539, 6666, 0
ICD-O-3
NA
3.8
7.6
30
80
09992
ICD-8 Finland
Other veneral disease, Condyloma acuminatum
10.1
7.5
14
14
TQW40
NOMESCO Finland
Remowal of suture of skin
1.9
7.5
101
538
M79.6
ICD-10 Finland
Pain in limb
1.4
7.5
501
4004
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
3.4
7.4
34
102
N06AB04
ATC
citalopram; systemic
1.5
7.4
309
2256
H02AB06
ATC
prednisolone; systemic
1.4
7.4
605
4995
L04AA01
ATC
[U] ciclosporin; systemic
3.8
7.4
29
77
SPAT1262
SPAT
Handing over of treatment supplies
1.6
7.3
181
1170
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.4
7.3
15
18
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
7.3
105
574
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
7.3
231
1588
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
7.2
123
713
A02BC03
ATC
lansoprazole; oral
1.4
7.2
379
2892
E000006
ATC
NA
1.9
7.2
108
599
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
7.2
197
1308
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
7.1
117
671
N30.0
ICD-10 Finland
Acute cystitis
1.6
7.1
215
1460
8511
FHL
Cervical dilation and drainage with suction
2.0
7.1
84
428
A02BX02
ATC
sucralfate; oral
2.5
7.1
54
225
N05BA04
ATC
oxazepam; oral
1.4
7.1
338
2534
J01CA08
ATC
pivmecillinam; oral
1.3
7.1
725
6193
LEB10
NOMESCO Finland
Excision of lesion of vagina
5.6
7.1
19
34
Z01.2
ICD-10 Finland
Dental examination
1.4
7.1
566
4650
KA1AE
NOMESCO Finland
Kidney ultrasound examination
4.2
7.0
25
61
R06AE07
ATC
cetirizine; oral
1.4
7.0
629
5260
A10AE05
ATC
insulin detemir; parenteral
2.2
7.0
64
292
H3600, E103
ICD-10 Finland
NA
4.5
7.0
23
52
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
5.5
6.9
19
35
M01AB05
ATC
diclofenac; systemic, rectal
1.4
6.9
915
8121
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.9
917
8148
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
6.8
208
1416
L57.0
ICD-10 Finland
Actinic keratosis
1.9
6.8
97
531
K59.0
ICD-10 Finland
Constipation
2.1
6.8
70
338
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.9
6.7
95
519
G44.2
ICD-10 Finland
Tension-type headache
1.6
6.7
203
1379
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
6.7
143
890
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.5
6.6
50
208
103
Kela drug reimbursment
Diabetes, insulin-treated
1.5
6.6
238
1686
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
1.7
6.5
129
785
ZXA05
NOMESCO Finland
Left side
1.4
6.5
304
2263
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.9
6.5
15
22
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.7
6.5
120
716
D28.0
ICD-10 Finland
Benign neoplasm: Vulva
6.2
6.5
16
26
B02AA02
ATC
tranexamic acid; systemic
1.5
6.4
271
1977
N03AX12
ATC
gabapentin; oral
1.5
6.4
206
1416
6230A
ICD-9 Finland
Noninflammatory disorders of vagina, Dysplasia of vagina[DYSPLASIA VAGINAE LEVIS]
70.1
6.4
7
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.1
6.4
67
324
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.6
6.4
174
1153
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.3
753
6533
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.3
138
862
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
6.3
108
628
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
6.3
86
464
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
3.9
6.3
24
63
ZZR00
NOMESCO Finland
Flap of skin
3.1
6.3
31
100
N08.5*M32.1
ICD-10 Finland
Glomerular disorders in systemic lupus erythematosus
18.1
6.3
9
5
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
6.2
160
1046
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
5.8
6.1
16
28
J01FA06
ATC
roxithromycin; oral
1.3
6.1
557
4637
R03AC02
ATC
salbutamol; inhalant
1.3
6.1
730
6327
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
12.6
6.1
10
8
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
2.1
6.1
67
331
R06.0
ICD-10 Finland
Dyspnoea
1.4
6.1
292
2185
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
6.0
225
1598
LFW96
NOMESCO Finland
Other operation on vulva or perineum
10.1
6.0
11
11
6160A
ICD-9 Finland
Inflammatory disease of cervix, vagina and vulva, Cervicitis and endocervicitis
10.1
6.0
11
11
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
6.0
173
1160
N06AX16
ATC
venlafaxine; oral
1.5
6.0
200
1388
N06AX11
ATC
mirtazapine; oral
1.4
6.0
418
3335
C07AA05
ATC
propranolol; systemic
1.4
6.0
281
2093

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
279
296
11.19
243.34
2.9
1.7
—
—
—
0
0
960
6238
2.34
58.59
3.9
2.0
—
—
—
0
0
40
40
10.23
35.47
1.7
1.8
8.5
2.0
ug/l
0.49
25
20
263
1225
2.37
32.39
1.5
1.4
—
—
—
0
0
324
1815
1.98
24.38
1.3
1.2
—
—
—
0
0
272
1449
2.06
23.49
2.3
1.7
—
—
—
0
0
605
4195
1.71
22.33
2.8
2.2
—
—
—
0
0
536
3643
1.71
21.01
4.4
2.9
40.4
73.2
e6/l
0.74
421
2712
318
1864
1.88
20.57
3.5
2.6
4.4
4.6
e6/l
0.16
190
915
173
814
2.26
20.39
11.7
6.7
8.5
8.2
mmol/l
0.27
165
779
478
3183
1.71
20.01
2.5
2.1
—
—
—
0
0
747
5588
1.63
19.87
6.5
4.1
35.7
36.2
g/l
1.63
715
5200
626
4490
1.65
19.66
5.1
3.4
71.8
91.9
e6/l
0.58
464
2988
626
4495
1.64
19.54
7.4
5.6
—
—
—
0
0
321
1939
1.82
18.70
4.0
3.0
0.8
0.8
mmol/l
2.16
308
1807
1088
9034
1.63
18.03
5.9
4.4
108.6
2215.1
e6/l
—
7
111
486
3335
1.66
17.78
4.2
2.8
—
—
—
0
0
485
3357
1.64
17.01
4.3
2.8
0.2
0.4
e6/l
2.28
376
2457
808
6316
1.56
16.81
4.6
3.8
—
—
—
0
0
759
5854
1.56
16.73
7.3
5.0
1.2
1.2
mmol/l
0.84
695
5308
250
1448
1.86
16.52
9.6
4.4
1.1
1.0
mmol/l
1.11
235
1324
323
2031
1.74
16.18
3.2
2.5
1.3
1.2
e6/l
0.02
194
1079
279
1684
1.79
16.09
2.5
1.9
—
—
—
0
0
866
6930
1.54
15.83
6.9
5.6
9.2
10.0
umol/l
3.04
838
6566
475
3325
1.61
15.68
5.2
3.3
97.4
96.9
%
0.18
463
3221
208
1164
1.90
15.24
2.6
2.0
0.2
0.2
g/l
0.18
201
1101
566
4154
1.56
15.14
3.0
2.3
53.3
55.5
u/l
0.95
536
3826
819
6517
1.52
15.07
8.2
5.7
1.2
1.2
mmol/l
1.87
718
5506
353
2320
1.67
14.89
4.1
2.5
487.0
514.3
mosm/kgh2o
1.63
312
1969
1106
9412
1.56
14.73
5.8
4.3
—
—
—
0
0
507
3649
1.57
14.69
4.5
3.0
6.3
6.7
mmol/l
1.61
421
3104
580
4309
1.54
14.54
3.5
3.0
—
—
—
0
0
77
292
2.72
14.42
3.3
2.8
1.6
1.4
mg/l
1.32
72
272
1207
10512
1.59
14.22
9.5
7.0
76.3
76.2
u/l
0.06
1146
9890
969
8068
1.51
13.82
11.4
8.7
3.9
3.9
e9/l
0.08
870
7088
497
3613
1.54
13.56
9.0
6.2
—
—
—
0
0
368
2525
1.59
12.83
3.7
2.4
7.2
8.1
e6/l
0.44
320
2214
468
3392
1.54
12.81
4.3
3.1
191.8
434.2
mg/l
0.95
301
1951
844
6909
1.47
12.57
7.9
5.5
0.6
0.5
e9/l
1.12
764
6024
865
7115
1.47
12.56
7.9
5.6
1.9
2.0
e9/l
0.83
801
6327
874
7206
1.47
12.52
8.1
5.7
0.2
0.2
e9/l
0.93
808
6366
845
6935
1.46
12.31
7.9
5.5
0.0
0.0
e9/l
0.33
765
6037
836
6857
1.46
12.16
4.5
3.7
0.0
0.0
estimate
1.32
131
1223
829
6796
1.45
12.05
5.9
5.0
0.0
0.0
estimate
0.50
134
1226
405
2881
1.54
11.94
5.1
3.9
—
—
—
0
0
21
36
5.90
11.81
2.8
2.5
—
—
—
0
0
672
5314
1.45
11.71
2.1
1.9
100.1
98.7
pmol/l
0.27
341
2617
814
6689
1.44
11.45
7.9
5.7
28.4
29.2
%
1.27
763
6240
478
3549
1.49
11.43
5.2
3.8
12.8
7.5
mg/mmol
1.18
308
2073
793
6496
1.44
11.28
8.1
5.9
8.2
8.1
%
0.30
743
6091
420
3047
1.51
11.20
2.9
2.8
901.0
866.8
ng/l
0.09
357
2542
1188
10507
1.50
11.18
5.1
4.1
12.6
11.7
mm/h
1.49
1119
9772
300
2023
1.59
11.10
1.2
1.2
—
—
—
0
0
803
6609
1.43
11.04
7.7
5.5
57.1
56.6
%
0.67
755
6182
881
7375
1.43
11.01
5.7
4.0
6.7
6.5
mmol/l
1.38
832
6850
786
6458
1.42
10.83
7.9
5.6
2.9
2.8
%
0.79
735
6012
232
1486
1.66
10.54
2.9
2.3
5.8
6.2
umol/l
0.20
202
1275
234
1505
1.65
10.46
1.7
1.5
—
—
—
0
0
243
1583
1.63
10.32
3.9
2.3
21.5
22.5
%
0.61
212
1362
114
597
1.98
10.11
1.2
1.2
—
—
—
0
0
284
1934
1.57
9.99
3.5
2.2
12.9
13.4
umol/l
0.63
263
1787
146
833
1.83
9.99
9.0
7.0
—
—
—
0
0
758
6246
1.40
9.97
8.0
5.7
0.7
0.7
%
0.58
709
5813
261
1745
1.59
9.94
3.6
2.2
2.3
2.4
g/l
3.14
238
1615
392
2879
1.48
9.64
1.6
1.5
23.3
21.7
nmol/l
0.54
351
2494
148
860
1.79
9.53
1.4
1.2
—
—
—
0
0
1478
13880
1.80
9.46
18.8
12.1
19.5
19.8
mg/l
0.14
1221
10771
805
6739
1.39
9.46
4.5
3.6
0.0
0.0
estimate
0.00
127
1219
507
3924
1.43
9.41
5.8
3.5
7.4
7.4
ph
0.23
77
720
400
2979
1.46
9.09
1.5
1.4
2.1
2.2
g/l
0.83
228
1817
113
613
1.91
9.06
4.4
3.1
5.1
5.2
kpa
1.10
105
573
111
608
1.89
8.65
4.4
3.0
7.4
7.4
ph
0.02
16
78
311
2236
1.48
8.39
1.8
1.7
1198.2
1204.5
nmol/l
0.04
253
1675
206
1356
1.60
8.32
18.7
19.8
1.3
1.2
inr
0.13
25
198
571
4587
1.38
8.30
9.5
7.2
1.2
1.1
inr
0.22
147
1397
154
944
1.70
8.23
5.7
3.0
5.9
5.8
kpa
0.10
148
917
414
3153
1.42
8.22
4.4
3.6
—
—
—
0
0
161
999
1.68
8.22
3.3
2.8
10.2
10.4
g/l
0.26
149
914
152
931
1.70
8.14
5.7
3.0
2.1
2.1
mmol/l
0.05
125
762
303
2186
1.48
8.01
1.5
1.4
645.3
581.4
titre
0.24
76
470
81
409
2.03
8.00
1.4
1.4
344.3
308.0
ug/g
0.67
49
229
85
439
1.99
7.89
2.5
1.9
1.6
1.5
g/l
0.16
71
383
247
1714
1.52
7.88
2.6
1.9
28.7
29.3
s
1.29
241
1656
484
3820
1.38
7.72
2.3
2.1
116.5
159.4
u/l
1.50
461
3604
89
472
1.94
7.66
6.4
3.2
24.2
24.4
mmol/l
0.24
81
428
12
18
6.71
7.61
1.2
1.1
23.4
47.7
ng/l
—
5
12
161
1035
1.62
7.16
5.1
3.1
102.3
74.5
ng/l
2.18
143
896
52
231
2.29
7.11
1.6
1.3
—
—
—
0
0
76
394
1.97
7.01
1.3
1.2
—
—
—
0
0
305
2258
1.43
6.97
3.9
3.3
88.4
300.4
ng/l
3.06
201
1522
329
2472
1.42
6.92
3.0
2.8
2.4
2.4
mmol/l
0.02
276
2174
85
460
1.90
6.91
1.2
1.2
—
—
—
0
0
228
1601
1.49
6.84
1.6
1.4
—
—
—
0
0
419
3289
1.37
6.77
2.5
2.2
3.1
2.9
mg/l
0.64
371
2803
127
780
1.68
6.75
1.8
1.8
1.3
1.4
g/l
0.16
115
713
48
211
2.31
6.74
1.6
1.3
109.2
121.6
u/ml
—
9
40
52
237
2.23
6.71
3.8
2.6
24.4
25.3
mmol/l
0.78
43
211
125
766
1.69
6.70
4.6
2.5
4.9
4.6
kpa
0.65
116
741
15
32
4.72
6.69
1.5
1.3
—
—
—
0
0
1477
14052
1.62
6.62
20.0
13.0
139.5
139.7
mmol/l
2.01
1455
13710
12
21
5.75
6.59
1.8
3.7
—
—
—
0
0
577
4777
1.32
6.49
4.1
3.3
2.4
2.4
mmol/l
0.29
505
4230
168
1119
1.56
6.43
3.0
3.3
4.3
4.5
pmol/l
0.72
142
993
199
1379
1.51
6.36
2.1
2.0
373.3
373.7
nmol/l
0.01
183
1262
149
971
1.59
6.27
1.4
1.4
—
—
—
0
0
1478
14091
1.60
6.23
20.4
13.1
3.9
3.9
mmol/l
0.53
1456
13711
261
1924
1.43
6.06
2.0
2.2
168.3
103.7
ug/g
1.13
197
1509
1421
13448
1.48
6.03
6.1
5.3
1.8
2.1
mu/l
1.13
1332
12545
15
35
4.32
6.03
1.8
1.5
—
—
—
0
0
49
229
2.18
5.98
1.8
1.7
—
—
—
0
0
174
1195
1.51
5.80
3.1
2.5
1.9
1.8
%
0.17
155
1053
72
392
1.88
5.79
5.5
3.1
—
—
—
0
0
408
3260
1.34
5.75
1.9
1.7
1.0
0.9
mg/l
0.37
315
2440
71
387
1.87
5.70
2.9
2.9
0.4
0.3
g/l
0.29
33
125
366
2881
1.35
5.69
4.7
4.1
1.0
1.0
kg/l
1.02
58
413
769
6699
1.28
5.68
3.5
2.8
100.5
82.4
ug/l
1.89
723
6279
413
3312
1.33
5.67
2.8
2.2
2940.6
4181.4
umol/l
0.34
362
2882
23
76
3.06
5.65
2.4
2.6
663.6
733.9
e6/l
—
8
33
1514
14568
1.67
5.53
16.4
11.3
—
—
—
0
0
78
445
1.79
5.43
4.7
3.1
—
—
—
0
0
29
112
2.62
5.40
2.3
2.4
1.2
1.2
e9/l
0.03
19
71
312
2419
1.36
5.33
2.0
1.7
—
—
—
0
0
1529
14764
1.72
5.32
13.2
9.8
23.8
23.9
u/l
0.18
1492
14326
441
3597
1.31
5.32
3.9
3.4
—
—
—
0
0
1274
11896
1.34
5.31
5.1
4.5
14.8
14.6
pmol/l
1.45
1191
11048
138
925
1.54
5.16
7.1
5.7
1.2
1.3
mmol/l
0.77
130
891
130
860
1.56
5.16
2.6
2.6
69.9
73.9
e9/l
0.64
98
633
41
190
2.19
5.15
2.0
2.4
30.1
33.6
umol/l
0.43
35
166
177
1250
1.47
5.15
2.5
2.2
30.8
35.6
u/l
1.08
149
1065
130
861
1.55
5.13
2.4
2.9
213.6
157.6
ng/l
0.63
115
770
104
656
1.63
5.04
2.2
1.9
—
—
—
0
0
543
4582
1.28
5.00
3.8
3.1
20.0
35.4
ng/l
0.95
327
2623
21
71
2.98
4.99
6.1
3.2
—
—
—
0
0
24
88
2.75
4.95
1.8
1.9
13.0
12.0
%
0.13
14
35
212
1562
1.41
4.91
1.4
1.3
—
—
—
0
0
19
62
3.09
4.80
2.2
2.7
32.6
47.4
%
—
5
20
46
230
2.03
4.78
1.4
1.2
327.0
269.2
u/ml
0.65
34
143
24
90
2.69
4.75
1.8
1.9
73.4
73.5
%
0.02
24
84
36
164
2.22
4.74
4.0
2.2
—
—
—
0
0
697
6093
1.25
4.69
11.6
8.4
0.0
0.0
e9/l
0.00
601
4970
431
3556
1.29
4.69
1.3
1.3
1.9
1.5
u/ml
0.16
110
945
264
2037
1.35
4.62
1.7
1.6
—
—
—
0
0
56
304
1.87
4.61
1.2
1.4
—
12.7
—
0
7
11
25
4.42
4.56
5.6
4.5
—
—
—
0
0
168
1203
1.44
4.56
6.4
6.7
0.9
1.3
mmol/l
0.62
132
938
168
1206
1.44
4.50
6.6
6.7
13.1
13.0
kpa
0.09
162
1148
168
1206
1.44
4.50
6.6
6.7
5.1
5.1
kpa
0.10
162
1149
101
659
1.57
4.29
1.4
1.3
0.5
1.0
u/ml
0.46
13
56
12
31
3.89
4.26
1.6
1.8
230.0
156.1
e6/l
—
7
18
147
1042
1.45
4.22
6.8
7.2
95.8
96.1
%
0.23
141
1001
441
3692
1.27
4.20
1.7
1.6
1.4
1.4
mmol/l
0.48
386
3177
425
3545
1.27
4.17
5.1
4.0
0.0
0.0
estimate
1.08
135
1234
23
91
2.55
4.14
3.2
2.9
374.3
25.3
mg/l
0.55
13
58
73
446
1.67
4.06
1.3
1.3
12.7
8.1
u/ml
—
9
51
14
42
3.35
4.04
1.7
1.9
32.9
26.6
%
0.94
14
37
46
247
1.89
3.96
2.4
1.9
123.0
130.1
g/l
1.29
32
177
86
552
1.59
3.94
7.3
7.8
24.2
24.4
mmol/l
0.24
79
514
52
291
1.81
3.93
1.8
2.2
—
—
—
0
0
23
94
2.47
3.89
2.4
2.1
—
—
—
0
0
95
627
1.55
3.87
1.9
1.9
2271.9
3093.7
u/l
0.21
33
244
357
2940
1.28
3.86
1.4
1.3
24.7
29.0
iu/ml
0.45
94
944
15
49
3.08
3.81
1.7
1.3
—
—
—
0
0
28
130
2.17
3.58
5.7
3.0
—
—
—
0
0
38
199
1.93
3.55
1.7
1.3
—
—
—
0
0
127
911
1.43
3.46
3.1
2.9
—
—
—
0
0
27
126
2.16
3.42
1.2
1.3
—
—
—
0
0
1382
13264
1.30
3.27
4.2
3.7
1.3
1.2
mmol/l
2.18
1288
12313
1313
12535
1.26
3.17
6.6
5.1
39.8
38.8
mmol/mol
3.08
1235
11713
173
1328
1.34
3.14
1.5
1.4
—
—
—
0
0
72
471
1.55
3.10
4.1
1.9
0.2
0.2
g/l
0.72
72
445
28
139
2.03
3.06
2.4
2.5
—
—
—
0
0
74
489
1.54
3.05
4.0
1.8
1.1
1.2
g/l
1.57
74
459
13
45
2.90
3.02
1.2
1.2
—
—
—
0
0
16
63
2.56
2.96
3.1
3.4
—
—
—
0
0
137
1026
1.37
2.93
2.6
2.6
4.3
4.1
e9/l
0.48
108
830
59
374
1.60
2.92
2.2
2.1
10.5
11.0
mg/l
0.29
53
344
6
9
6.69
2.87
4.7
14.0
4.2
5.7
mmol/l
—
6
9
1571
15445
1.73
2.87
26.8
18.1
91.1
90.8
fl
2.15
1557
15274
116
849
1.39
2.86
2.3
2.2
3.6
5.5
ug/l
1.56
104
732
1571
15446
1.72
2.85
26.8
18.1
30.2
30.1
pg
1.61
1557
15274
1571
15447
1.72
2.84
26.9
18.2
4.4
4.4
e12/l
3.79
1540
15086
59
377
1.59
2.83
1.2
1.1
—
—
—
0
0
1571
15448
1.72
2.82
27.0
18.2
6.7
6.6
e9/l
0.98
1542
15084
109
793
1.40
2.79
1.4
2.3
—
—
—
0
0
1570
15439
1.70
2.77
27.0
18.2
267.0
266.7
e9/l
0.08
1545
15114
1014
9491
1.18
2.73
4.1
3.3
—
—
—
0
0
1571
15455
1.70
2.71
27.1
18.3
131.7
132.7
g/l
2.27
1558
15281
125
936
1.36
2.70
1.6
2.6
65.0
67.2
g/l
1.84
108
859
134
1017
1.35
2.66
4.7
3.5
—
—
—
0
0
35
198
1.78
2.65
5.7
1.9
—
—
—
0
0
37
213
1.75
2.64
6.2
2.9
—
—
—
0
0
22
106
2.09
2.63
1.5
1.2
—
—
—
0
0
5
7
7.16
2.55
1.0
1.0
—
—
—
0
0
162
1273
1.30
2.53
1.2
1.2
—
—
—
0
0
5
8
6.27
2.37
6.0
1.5
—
—
—
0
0
16
71
2.27
2.34
3.1
3.2
—
—
—
0
0
56
374
1.52
2.27
1.3
1.2
270.0
108.0
titre
—
6
25
61
415
1.49
2.27
3.7
1.6
—
—
—
0
0
58
392
1.50
2.23
1.4
1.4
37.6
29.9
u/l
0.89
49
316
9
29
3.12
2.22
1.0
1.0
—
—
—
0
0
72
1001
0.71
2.22
1.4
1.4
—
—
—
0
0
16
73
2.20
2.21
1.7
1.4
—
—
—
0
0
76
547
1.41
2.13
9.4
9.3
—
—
—
0
0
164
1326
1.26
2.08
4.1
3.7
—
—
—
0
0
89
661
1.37
2.08
5.5
5.2
—
—
—
0
0
45
293
1.55
2.07
4.2
2.4
—
—
—
0
0
38
238
1.61
2.05
3.3
2.5
109.8
98.8
ug/min
0.05
25
155
52
353
1.49
1.99
4.2
1.5
—
—
—
0
0
62
436
1.44
1.99
10.7
7.9
—
—
—
0
0
53
362
1.48
1.97
1.4
1.2
—
—
—
0
0
50
338
1.49
1.96
2.6
2.1
—
—
—
0
0
327
2856
1.18
1.94
1.4
1.3
8.0
10.8
u/ml
0.39
122
1148
322
2811
1.18
1.92
1.7
1.6
488.5
28632555.9
pmol/l
2.47
273
2354
64
458
1.41
1.88
3.8
1.6
—
—
—
0
0
482
5315
0.87
1.88
2.9
2.6
—
—
—
0
0
123
974
1.28
1.87
1.4
1.4
—
—
—
0
0
15
72
2.09
1.86
2.9
2.6
0.2
0.4
e9/l
0.50
15
72
30
182
1.66
1.85
1.1
1.3
—
—
nmol/l
—
0
0
25
144
1.75
1.85
1.4
1.5
—
—
—
0
0
64
460
1.41
1.84
3.8
1.6
—
—
—
0
0
26
152
1.72
1.84
2.1
2.2
—
—
—
0
0
34
215
1.59
1.80
3.3
2.1
15.8
16.4
%
0.43
23
101
69
505
1.38
1.80
2.8
1.7
22.0
20.7
s
1.08
59
431
26
154
1.70
1.76
1.6
1.5
—
—
—
0
0
6
18
3.34
1.74
1.0
1.2
—
—
—
0
0
8
30
2.67
1.72
1.1
1.2
—
—
—
0
0
8
30
2.67
1.72
1.0
1.1
—
—
—
0
0
35
226
1.56
1.71
1.0
1.2
—
—
—
0
0
15
75
2.01
1.69
1.7
1.6
—
—
—
0
0
31
195
1.60
1.69
1.1
1.3
—
—
—
0
0
33
211
1.58
1.68
1.1
1.3
—
0.4
nmol/l
—
0
10
38
252
1.52
1.66
1.3
1.2
—
—
—
0
0
414
3727
1.15
1.65
4.0
3.3
—
—
—
0
0
7
25
2.81
1.65
2.4
1.3
—
—
—
0
0
85
653
1.32
1.64
6.7
7.1
24.7
24.8
mmol/l
0.13
78
603
26
158
1.66
1.62
1.6
1.7
65.5
52.3
%
0.81
15
92
5
14
3.58
1.61
6.0
6.5
—
—
—
0
0
5
14
3.58
1.61
1.6
1.4
5.4
4.5
mmol/l
—
5
7
28
174
1.62
1.61
1.6
1.4
331.3
308.9
pmol/l
0.14
21
132
36
238
1.52
1.60
1.1
1.2
2.1
4.5
u/ml
1.14
19
91
62
456
1.37
1.60
3.9
1.6
—
—
—
0
0
61
448
1.38
1.58
4.0
1.6
—
—
—
0
0
403
3637
1.14
1.55
1.5
1.5
—
—
—
0
0
33
216
1.54
1.54
1.1
1.1
—
—
—
0
0
15
78
1.93
1.54
1.5
1.4
5596.6
114638.0
e6/l
—
10
42
5
15
3.34
1.52
1.0
1.1
—
—
—
0
0
32
209
1.54
1.52
1.1
1.1
—
—
—
0
0
17
93
1.84
1.51
1.0
1.1
—
—
—
0
0
16
86
1.87
1.50
1.0
1.0
—
—
—
0
0
155
1304
1.21
1.42
3.6
3.8
3.6
13.2
ug/l
1.90
121
1020
41
287
1.44
1.42
8.1
3.0
7.4
7.4
ph
1.05
35
228
16
88
1.83
1.41
1.0
1.3
—
—
—
0
0
1435
14058
1.19
1.41
5.3
4.5
2.8
2.9
mmol/l
2.18
1338
13118
128
1538
0.82
1.40
1.3
1.3
—
—
—
0
0
10
46
2.18
1.40
5.9
1.5
—
—
—
0
0
34
230
1.49
1.39
9.0
3.2
2.4
2.8
mmol/l
0.33
26
161
7
29
2.42
1.39
1.4
1.4
31.1
40.7
%
—
7
22
26
166
1.58
1.37
7.1
2.0
58.9
61.5
%
0.24
26
166
18
104
1.74
1.37
2.6
2.4
61.2
54.6
%
0.65
13
67
9
41
2.20
1.37
1.0
1.2
197.9
318.1
pmol/l
—
9
31
44
315
1.41
1.36
2.0
1.4
23.6
12.6
e6/l
0.28
32
237
44
315
1.41
1.36
2.1
1.5
351.1
1494.5
e6/l
0.71
37
253
38
266
1.44
1.33
5.1
2.0
—
—
—
0
0
33
225
1.48
1.31
1.1
1.1
—
—
—
0
0
32
217
1.48
1.31
5.1
2.6
—
—
—
0
0
1414
13850
1.17
1.30
4.9
4.1
4.8
4.9
mmol/l
1.86
1332
12995
6
24
2.51
1.30
2.3
2.5
22.5
20.9
umol/l
—
6
24
5
18
2.78
1.28
1.0
1.0
5.7
5.5
nmol/l
—
5
18
1405
13765
1.16
1.24
4.8
4.1
1.6
1.6
mmol/l
1.76
1309
12853
81
646
1.27
1.24
1.1
1.1
—
—
—
0
0
10
49
2.05
1.22
1.9
2.0
—
—
—
0
0
10
49
2.05
1.22
1.9
2.0
8.7
9.5
%
—
10
49
68
532
1.29
1.21
1.7
1.6
287.6
320.4
mu/l
0.58
59
477
8
37
2.17
1.21
2.5
1.2
—
—
—
0
0
130
1096
1.20
1.20
2.4
2.4
15.9
22.4
au/ml
—
10
75
18
109
1.66
1.19
1.5
1.6
32.9
41.0
%
0.38
12
58
19
117
1.63
1.18
1.5
1.5
6895.5
74068.4
e6/l
0.61
13
75
33
232
1.43
1.15
1.1
1.7
—
—
—
0
0
39
283
1.39
1.15
3.6
3.7
57.7
58.4
%
0.14
39
283
10
51
1.97
1.11
1.2
1.2
—
—
—
0
0
53
407
1.31
1.10
6.7
4.4
—
—
—
0
0
1378
13508
1.14
1.08
5.1
4.2
5.9
5.8
mmol/l
2.80
1279
12488
15
89
1.69
1.07
1.5
1.4
5.1
5.5
u/l
—
10
78
39
289
1.36
1.03
2.1
1.5
—
—
—
0
0
26
179
1.46
1.03
1.1
1.2
—
—
—
0
0
17
106
1.61
1.03
1.1
1.8
—
—
—
0
0
41
307
1.34
1.02
1.2
3.6
41.4
50.5
mg/l
0.25
33
252
41
308
1.34
1.00
1.2
3.6
31.3
37.7
mg/l
0.25
34
251
15
91
1.65
1.00
1.0
1.1
—
—
—
0
0
47
361
1.31
1.00
1.2
2.2
35.7
38.1
g/l
1.29
41
322
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
145
1261
1.16
0.97
1.5
1.6
—
—
—
0
0
22
149
1.48
0.95
1.7
1.5
—
—
—
0
0
17
109
1.57
0.93
1.6
2.4
2.9
2.1
u/field
—
9
53
45
348
1.30
0.92
1.0
1.1
—
—
—
0
0
31
228
1.37
0.89
1.3
3.9
—
—
—
0
0
17
111
1.54
0.87
2.5
2.7
—
—
—
0
0
26
186
1.40
0.87
3.4
3.4
0.8
0.8
nmol/l
0.16
18
141
8
43
1.86
0.87
1.3
1.3
—
—
—
0
0
71
587
1.22
0.85
1.4
1.3
217.2
229.6
miu/ml
0.11
31
299
12
72
1.67
0.85
1.2
1.2
—
—
—
0
0
13
80
1.63
0.84
2.5
2.1
9.3
10.9
%
0.81
13
80
6
31
1.94
0.84
1.5
1.2
—
—
—
0
0
8
45
1.78
0.84
1.5
2.3
—
—
—
0
0
20
137
1.47
0.84
1.1
1.1
—
—
—
0
0
20
137
1.47
0.84
2.0
1.3
—
—
—
0
0
20
137
1.47
0.84
2.0
1.3
—
—
—
0
0
20
137
1.47
0.84
2.0
1.3
—
—
—
0
0
20
137
1.47
0.84
2.0
1.3
—
—
—
0
0
178
1591
1.13
0.84
1.5
1.4
—
—
—
0
0
8
46
1.74
0.82
1.6
2.0
—
—
—
0
0
6
32
1.88
0.82
1.0
1.1
—
—
—
0
0
175
1566
1.13
0.81
1.8
1.7
—
—
—
0
0
28
207
1.36
0.79
1.2
1.4
—
—
—
0
0
11
66
1.67
0.78
2.7
2.0
30.6
139.0
ug/l
0.44
11
59
25
182
1.38
0.78
1.5
1.5
—
—
—
0
0
17
115
1.48
0.77
3.1
3.4
—
—
—
0
0
19
132
1.44
0.76
2.6
2.5
—
—
—
0
0
10
59
1.70
0.76
1.2
1.1
—
—
—
0
0
76
643
1.19
0.75
4.1
3.2
—
—
—
0
0
115
1007
1.15
0.75
4.6
4.3
0.0
0.8
%
0.86
33
219
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
126
1114
1.14
0.72
4.3
4.1
0.8
0.9
%
0.25
41
284
12
76
1.58
0.71
1.7
1.5
—
—
—
0
0
38
301
1.27
0.69
1.1
1.2
20.2
16.9
u/l
0.46
32
235
18
128
1.41
0.65
1.3
1.3
—
—
—
0
0
84
728
1.16
0.65
2.3
2.3
—
—
—
0
0
144
1296
1.12
0.64
1.2
1.2
158.8
158.9
iu/ml
0.00
45
517
120
1068
1.13
0.64
4.5
4.2
0.1
0.1
%
1.10
39
259
102
1154
0.88
0.63
1.6
1.8
—
—
—
0
0
72
618
1.17
0.63
1.6
1.7
—
—
—
0
0
120
1070
1.13
0.62
1.2
1.2
—
—
—
0
0
119
1062
1.13
0.61
1.4
1.3
259.9
154.8
u/ml
0.43
110
987
18
130
1.39
0.61
1.1
1.0
—
—
—
0
0
19
139
1.37
0.60
2.1
2.5
—
—
—
0
0
17
122
1.40
0.60
3.0
2.7
—
—
—
0
0
18
132
1.37
0.57
1.5
2.0
33.1
31.7
pg
0.49
18
132
114
1022
1.12
0.56
4.1
3.9
0.2
0.7
%
3.35
28
202
345
3261
1.07
0.55
5.2
4.3
—
—
—
0
0
32
257
1.25
0.55
1.1
1.1
4.7
3.2
u/ml
0.24
17
129
17
125
1.36
0.53
1.5
1.5
—
—
—
0
0
45
377
1.20
0.53
2.3
2.0
1.0
2.1
ug/l
0.66
39
333
1309
12909
1.08
0.53
19.0
13.1
38.7
39.2
%
1.60
1001
9831
6
39
1.54
0.53
3.0
3.3
—
—
—
0
0
30
242
1.24
0.51
1.8
1.6
—
—
—
0
0
13
92
1.42
0.50
1.1
1.2
—
—
—
0
0
7
110
0.63
0.48
5.9
6.9
—
—
—
0
0
7
46
1.52
0.48
1.6
1.2
—
—
—
0
0
5
81
0.62
0.46
1.8
1.4
—
—
—
0
0
33
274
1.21
0.45
1.1
1.2
—
—
—
0
0
5
31
1.61
0.43
3.6
2.0
—
—
—
0
0
124
1139
1.10
0.42
5.4
3.9
—
—
—
0
0
8
56
1.43
0.42
1.8
1.8
—
—
—
0
0
12
87
1.38
0.42
1.7
1.3
—
64.4
—
0
10
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
18
140
1.29
0.42
1.8
1.8
90.0
90.4
%
0.16
18
140
10
70
1.43
0.41
1.6
1.6
1.2
1.4
nmol/l
—
10
57
5
33
1.52
0.41
1.8
1.6
—
—
—
0
0
0
17
0.00
0.40
0.0
6.6
—
—
—
0
0
24
293
0.82
0.40
1.4
1.4
—
—
—
0
0
34
287
1.19
0.40
5.4
4.1
—
—
—
0
0
19
150
1.27
0.40
2.6
1.6
—
—
—
0
0
24
292
0.82
0.39
1.4
1.4
—
—
—
0
0
52
456
1.15
0.39
2.2
1.9
2.9
4.2
iu/l
1.43
22
177
13
97
1.34
0.39
1.3
1.2
—
—
—
0
0
47
410
1.15
0.38
3.2
3.1
40.8
554.0
u/ml
0.89
37
354
28
330
0.85
0.34
1.3
1.4
0.2
0.3
nmol/l
1.00
22
246
139
1301
1.07
0.33
1.2
1.3
33.6
32.9
iu/l
0.08
113
1129
6
46
1.31
0.33
1.3
2.2
7.8
9.3
mg/l
—
6
37
1191
11773
1.04
0.32
22.5
14.7
13.7
13.6
%
0.16
1174
11532
22
184
1.20
0.30
1.7
1.4
—
—
—
0
0
11
84
1.31
0.30
1.0
1.1
—
43.8
—
0
9
26
301
0.86
0.27
1.4
1.4
—
—
—
0
0
12
95
1.27
0.26
4.2
1.9
31.7
9.6
ug/l
0.39
12
78
16
132
1.21
0.25
2.1
2.1
—
—
—
0
0
29
255
1.14
0.24
1.1
1.1
—
—
—
0
0
59
543
1.09
0.23
1.3
1.3
—
—
—
0
0
29
256
1.14
0.23
1.1
1.1
—
—
—
0
0
1195
12052
0.97
0.22
23.6
15.6
330.7
330.9
g/l
0.22
1185
11975
24
274
0.87
0.22
1.0
1.1
0.0
1.3
u/ml
—
5
118
28
316
0.88
0.22
1.1
1.1
1.0
1.4
u/ml
—
5
119
5
40
1.25
0.22
1.0
1.1
—
—
—
0
0
36
399
0.90
0.22
4.8
3.7
19.5
28.9
u/ml
1.10
36
385
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.1
—
0.0
—
0
5
0
13
0.00
0.21
0.0
1.0
—
0.0
—
0
7
0
13
0.00
0.21
0.0
7.5
—
—
—
0
0
0
13
0.00
0.21
0.0
2.3
—
49.5
—
0
13
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
21
183
1.15
0.20
1.4
1.6
3.3
5.3
ug/l
0.53
14
154
6
49
1.23
0.20
2.0
2.2
162.0
163.6
nmol/l
—
6
43
7
58
1.21
0.18
1.6
2.2
—
—
—
0
0
12
100
1.20
0.18
1.3
1.2
—
—
—
0
0
25
224
1.12
0.17
2.8
2.6
8.4
7.3
mmol/l
1.24
25
218
5
66
0.76
0.17
1.0
1.1
1410.8
1710.7
miu/ml
—
5
66
15
129
1.16
0.17
1.3
1.1
—
—
—
0
0
5
67
0.75
0.17
2.4
2.0
0.9
3.2
ug/l
—
5
58
24
215
1.12
0.16
1.0
1.1
—
—
—
0
0
6
76
0.79
0.15
1.7
1.5
128.5
128.3
nmol/l
—
6
76
19
212
0.89
0.14
1.0
1.1
80.7
2592.8
iu/ml
—
6
50
26
283
0.92
0.12
1.1
1.1
4.5
3.5
u/ml
—
8
136
15
169
0.89
0.12
3.7
5.0
9.1
76.6
u/ml
—
6
51
59
621
0.95
0.12
1.1
1.1
—
—
—
0
0
14
124
1.13
0.11
1.3
1.2
—
—
—
0
0
26
241
1.08
0.10
2.8
2.5
1.6
1.5
mmol/l
0.29
26
233
12
106
1.13
0.09
1.0
1.0
—
—
—
0
0
5
46
1.09
0.09
1.4
1.1
—
—
—
0
0
5
61
0.82
0.08
2.0
2.3
—
—
—
0
0
5
65
0.77
0.08
2.4
2.1
1.3
2.6
ug/l
—
5
55
10
88
1.14
0.08
14.1
11.2
0.7
0.7
mmol/l
—
10
79
7
67
1.04
0.08
1.0
1.5
—
—
—
0
0
15
137
1.10
0.07
1.6
1.4
280.3
278.1
mosm/kgh2o
—
10
103
21
225
0.93
0.07
1.1
1.0
0.9
2.7
u/ml
—
5
75
13
118
1.10
0.07
1.0
1.1
—
—
—
0
0
108
1057
1.02
0.06
5.8
3.2
1.2
1.2
mmol/l
0.53
98
913
9
102
0.88
0.06
2.0
1.4
1.5
1.4
nmol/l
—
9
92
10
111
0.90
0.06
1.1
1.2
—
—
—
0
0
24
249
0.96
0.02
1.2
1.2
—
—
—
0
0
13
138
0.94
0.02
1.2
1.1
—
—
—
0
0
27
272
0.99
0.00
4.1
3.7
19.9
22.0
mg/l
0.17
17
169
12
119
1.01
0.00
1.2
1.1
—
—
—
0
0
20
201
0.99
0.00
1.2
1.0
—
—
—
0
0
21
207
1.01
0.00
1.7
1.5
—
—
—
0
0
11
105
1.05
0.00
1.6
1.9
18.0
19.3
nmol/l
0.16
11
99
0
8
0.00
0.00
0.0
2.1
—
426.9
—
0
8
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
68
0.88
0.00
1.5
1.4
—
5.5
%
—
0
16
8
84
0.95
0.00
1.5
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
151.2
—
0
5
0
9
0.00
0.00
0.0
1.8
—
373.6
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
72.6
—
0
5
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
11.3
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.6
—
—
—
0
0
8
85
0.94
0.00
2.1
1.8
—
1.2
—
0
7
0
7
0.00
0.00
0.0
1.9
—
32.8
—
0
7

Mortality – FinRegistry

Association

Association between endpoint N14_VULVAL_DYSPLASIA_ALL and mortality.

Females

Parameter HR [95% CI] p-value
N14_VULVAL_DYSPLASIA_ALL 1.189 [1.04, 1.36] 0.011
Birth year 0.997 [0.99, 1.01] 0.487

During the follow-up period (1.1.1998 — 31.12.2019), 561 out of 4102 females with N14_VULVAL_DYSPLASIA_ALL died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VULVAL_DYSPLASIA_ALL.

N-year risk Females Males
1 0.119% No data
5 0.789% No data
10 1.98% No data
15 3.774% No data
20 6.424% No data

Relationships between endpoints

Index endpoint: N14_VULVAL_DYSPLASIA_ALL – All dysplastic lesions of the vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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