Dysplastic lesion of the vulva of unknown severity

N14_VULVAL_DYSPLASIA_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N90.3
  • Cause of death: ICD-10 N90.3

2 out of 7 registries used, show all original rules.

52

4. Check minimum number of events

None

52

5. Include endpoints

None

52

6. Filter based on genotype QC (FinnGen only)

52

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 290 290 -
Only index persons 280 280 -
Unadjusted period prevalence (%)
Whole population 0.01 0.01 -
Only index persons 0.01 0.01 -
Median age at first event (years)
Whole population - 59.03 -
Only index persons - 58.75 -

-FinnGen-

Key figures

All Female Male
Number of individuals 52 52 -
Unadjusted period prevalence (%) 0.02 0.02 -
Median age at first event (years) 56.48 56.48 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
16
7
32.04
12.49
1.9
2.1
—
—
—
0
0
23
98
3.42
4.38
4.5
3.6
—
—
—
0
0
21
91
3.19
3.81
3.8
3.7
—
—
—
0
0
12
41
3.50
3.10
1.3
1.3
—
—
—
0
0
32
191
2.76
3.09
4.4
2.1
—
—
—
0
0
5
6
9.04
2.81
1.0
1.3
—
—
—
0
0
21
108
2.58
2.64
4.9
2.5
—
—
—
0
0
23
125
2.51
2.57
4.4
2.6
15.8
28.2
e6/l
0.60
18
98
20
103
2.53
2.49
1.7
1.3
12.2
31.4
iu/ml
—
5
42
12
47
3.02
2.48
1.4
1.3
—
—
—
0
0
15
67
2.74
2.46
4.2
2.3
455.6
499.7
mosm/kgh2o
0.35
15
57
11
41
3.13
2.46
1.6
1.8
—
—
—
0
0
24
137
2.40
2.38
2.5
1.8
—
—
—
0
0
5
10
5.40
2.12
5.0
4.8
—
—
—
0
0
24
143
2.26
2.11
9.0
4.9
—
—
—
0
0
5
11
4.90
1.99
1.0
1.5
—
—
—
0
0
41
311
2.50
1.96
6.0
4.4
—
111.0
—
0
8
24
147
2.17
1.94
5.7
3.3
17.7
76.3
e6/l
1.33
18
103
12
54
2.59
1.91
2.2
1.6
—
—
—
0
0
8
30
2.96
1.81
1.5
1.4
—
—
—
0
0
12
57
2.44
1.71
1.3
1.2
—
—
—
0
0
20
119
2.11
1.70
6.5
6.5
—
—
—
0
0
18
105
2.09
1.60
1.7
2.1
274.3
9242.7
umol/l
1.08
13
89
9
37
2.73
1.57
1.1
1.1
—
—
—
0
0
40
314
2.19
1.55
6.1
4.2
—
—
—
0
0
24
158
1.96
1.52
3.2
2.7
—
—
—
0
0
5
17
3.14
1.39
4.8
2.2
23.6
24.6
mmol/l
—
5
17
10
48
2.34
1.38
1.4
1.4
—
—
—
0
0
26
181
1.87
1.37
6.0
3.5
—
—
—
0
0
6
24
2.69
1.34
1.2
2.0
—
—
—
0
0
13
71
2.11
1.34
1.5
1.6
—
—
—
0
0
5
18
2.96
1.31
5.0
2.1
126.4
127.5
g/l
—
5
18
12
64
2.14
1.31
1.3
1.3
—
—
—
0
0
6
26
2.47
1.22
4.3
2.3
5.1
5.6
kpa
—
6
26
5
20
2.65
1.18
1.4
1.5
—
—
—
0
0
17
109
1.83
1.12
1.9
1.3
54.1
15.6
u/ml
—
8
41
20
136
1.76
1.08
1.8
1.4
—
—
—
0
0
47
418
2.29
1.03
21.5
12.3
39.7
39.9
%
0.10
36
304
6
29
2.20
0.93
8.7
2.9
—
—
—
0
0
6
32
1.99
0.85
1.3
1.1
—
174.7
—
0
11
5
24
2.19
0.77
1.2
1.4
—
—
—
0
0
22
170
1.51
0.67
2.4
1.8
74.5
108.4
pmol/l
—
10
72
44
396
1.72
0.65
29.7
15.0
329.6
330.6
g/l
0.40
44
396
5
30
1.74
0.63
2.6
2.2
—
—
—
0
0
5
30
1.74
0.63
1.0
1.2
—
—
—
0
0
8
53
1.60
0.62
1.6
1.2
—
—
—
0
0
0
22
0.00
0.61
0.0
1.5
—
286.2
—
0
11
16
119
1.50
0.57
5.1
3.9
—
—
—
0
0
17
130
1.46
0.53
3.2
1.9
127.1
135.3
u/l
0.05
17
124
0
15
0.00
0.42
0.0
4.9
—
18.3
—
0
8
0
17
0.00
0.41
0.0
1.6
—
7.8
—
0
7
10
132
0.70
0.38
4.1
3.0
—
—
—
0
0
6
43
1.45
0.36
1.3
1.6
—
—
—
0
0
9
74
1.26
0.27
1.4
1.7
1865.4
1190.7
nmol/l
—
9
55
5
38
1.35
0.24
1.2
1.4
—
—
—
0
0
5
42
1.21
0.22
1.4
2.8
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
1.5
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
4.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
4.2
—
0
10
0
10
0.00
0.21
0.0
2.6
—
61.9
—
0
10
7
62
1.15
0.18
1.9
1.3
—
—
—
0
0
34
323
1.15
0.12
6.0
3.3
—
—
—
0
0
17
154
1.15
0.12
8.8
5.9
1.1
1.2
inr
—
5
60
10
86
1.20
0.12
1.8
1.7
—
—
—
0
0
15
166
0.86
0.12
2.3
2.7
—
—
—
0
0
15
165
0.87
0.10
9.1
3.1
11.8
20.3
ng/l
—
10
105
14
133
1.07
0.02
5.3
3.7
—
—
—
0
0
0
7
0.00
0.00
0.0
3.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
32.5
—
0
6
5
49
1.02
0.00
1.4
1.9
27.0
28.6
s
—
5
49
0
6
0.00
0.00
0.0
1.0
—
25.4
—
0
6
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_VULVAL_DYSPLASIA_NOS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_VULVAL_DYSPLASIA_NOS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: N14_VULVAL_DYSPLASIA_NOS – Dysplastic lesion of the vulva of unknown severity

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
loading spinner Loading data