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Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva

Endpoint Browser PheWeb

N14_FEMALE_GENITAL_DYSPLASIA_NOS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only females

293218

2. Check conditions

None

293218

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

483

4. Check minimum number of events

None

483

5. Include endpoints

None

483

6. Filter based on genotype QC (FinnGen only)

468

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Similar endpoints

↥

List of similar endpoints to Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2793 2793 -
Only index persons 2743 2743 -
Unadjusted period prevalence (%)
Whole population 0.08 0.08 -
Only index persons 0.10 0.10 -
Median age at first event (years)
Whole population - 41.62 -
Only index persons - 41.33 -

-FinnGen-

Key figures

All Female Male
Number of individuals 468 468 -
Unadjusted period prevalence (%) 0.17 0.17 -
Median age at first event (years) 43.16 43.16 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
483
Matched controls
4830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
4730.5
307.7
391
*
ULA02
NOMESCO Finland
Kolposcopy
20.1
256.6
332
477
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
13.7
185.8
240
325
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
16.1
175.1
179
170
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
10.5
152.4
259
481
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
9.5
140.5
269
564
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.0
112.4
141
174
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
12.1
87.2
96
97
N87.0
ICD-10 Finland
Mild cervical dysplasia
11.6
81.6
92
96
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
13.0
67.9
69
61
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
+∞
58.5
55
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
9.9
47.6
58
66
N87.1
ICD-10 Finland
Moderate cervical dysplasia
8.7
47.5
64
83
LEB00
NOMESCO Finland
Biopsy of vagina
10.9
41.3
46
46
N89.3
ICD-10 Finland
Dysplasia of vagina, unspecified
+∞
41.2
39
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
6.3
35.6
65
117
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.8
27.1
280
1591
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
49.3
16.1
19
*
LFC00
NOMESCO Finland
Partial excision of vulva
35.1
13.6
17
5
N90.0
ICD-10 Finland
Mild vulvar dysplasia
33.0
12.6
16
5
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
4.5
10.9
27
63
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
10.5
10
*
LCA06
NOMESCO Finland
Biopsy of endometrium
2.1
9.6
102
540
WX702
NOMESCO Finland
Supraglottic ventilation device
3.0
9.6
44
157
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
18.0
9.4
14
8
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
37.4
9.1
11
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.1
8.8
101
548
SPAT1193
SPAT
Pap smear
2.1
8.8
95
504
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
13.3
7.9
13
10
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
9.6
7.8
15
16
TLW99
NOMESCO Finland
Other minor surgical procedure in gynaecology
3.8
7.7
23
62
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
81.3
7.4
8
*
ZXC00
NOMESCO Finland
Use of diathermy
11.1
7.3
13
12
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
30.5
7.2
9
*
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
20.4
7.2
10
5
X86
ICPC
Abnormal cervix smear
6.2
7.1
18
30
SPAT1324
SPAT
Screening procedure
1.7
7.1
155
1031
WX704
NOMESCO Finland
Intubation
2.4
6.9
48
212
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
14.5
6.4
10
7
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
6.1
6.4
16
27
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
6.3
94
554
SPAT1263
SPAT
Sampling
1.6
6.3
203
1484
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
+∞
6.3
6
*
C53.01
ICD-10 Finland
Squamous cell carcinoma of the endocervix
27.1
6.2
8
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
6.2
35
140
N89.0
ICD-10 Finland
Mild vaginal dysplasia
8.8
6.1
12
14

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
104
125
10.33
83.36
2.2
1.7
—
—
—
0
0
40
194
2.16
4.65
2.6
2.4
91.74
136.59
ng/l
0.52
35
176
230
1832
1.49
4.42
2.8
2.0
—
—
—
0
0
250
2069
1.43
3.70
3.7
3.2
0.00
0.01
estimate
0.80
46
404
185
1457
1.44
3.56
4.3
3.9
35.83
36.63
g/l
1.15
174
1361
246
2040
1.42
3.55
3.8
3.2
0.00
0.00
estimate
-0.00
45
428
246
2046
1.41
3.46
5.0
4.4
0.00
0.00
estimate
0.50
45
414
95
659
1.55
3.41
1.4
1.4
618.95
567.79
titre
0.07
19
149
65
415
1.65
3.29
2.0
2.2
5.07
5.40
umol/l
0.18
52
354
53
321
1.73
3.25
1.4
1.4
—
—
—
0
0
118
866
1.48
3.24
4.0
3.2
1.02
1.02
kg/l
1.12
18
111
121
893
1.47
3.23
3.7
3.1
—
—
—
0
0
117
859
1.48
3.21
1.3
1.3
17.44
29.48
iu/ml
1.46
43
312
150
1163
1.42
3.07
2.7
2.2
54.55
57.25
u/l
0.47
140
1084
19
81
2.40
3.02
1.7
2.0
13.00
13.25
%
0.51
19
81
30
156
1.98
2.97
1.1
1.2
—
—
—
0
0
169
1352
1.38
2.85
4.2
2.8
32.33
27.78
u/l
0.62
161
1291
134
1037
1.40
2.73
5.1
3.2
7.41
7.40
ph
1.18
13
201
204
1712
1.33
2.45
5.8
5.1
1.22
1.22
mmol/l
0.05
180
1453
137
1084
1.37
2.42
4.0
3.4
0.00
0.01
estimate
1.08
45
414
225
1929
1.31
2.28
4.9
5.3
9.92
9.37
umol/l
0.48
212
1820
37
227
1.68
2.22
4.3
2.8
1.90
2.29
mmol/l
0.39
32
184
328
2968
1.33
2.21
7.4
6.5
72.08
74.02
u/l
0.48
310
2793
39
243
1.66
2.21
1.6
1.7
1.26
1.40
g/l
0.33
34
224
15
67
2.28
2.20
1.0
1.1
—
—
—
0
0
6
164
0.36
2.19
1.3
1.2
—
—
—
0
0
335
3043
1.33
2.18
4.2
3.8
10.37
10.10
mm/h
0.19
314
2836
7
19
3.72
2.16
1.1
1.2
—
—
—
0
0
7
19
3.72
2.16
2.0
2.3
40.34
51.72
%
—
7
12
14
62
2.30
2.09
1.4
1.7
0.72
0.69
g/l
—
9
46
39
248
1.62
2.06
1.5
1.4
—
—
—
0
0
5
147
0.33
2.04
1.2
1.8
—
—
—
0
0
108
855
1.34
1.87
1.3
1.3
20.20
14.60
u/ml
0.22
40
364
70
926
0.71
1.85
2.5
3.1
—
—
—
0
0
146
1212
1.29
1.80
3.1
2.5
—
—
—
0
0
16
81
2.01
1.76
1.4
1.5
—
—
—
0
0
30
187
1.64
1.73
3.8
2.4
2.55
5.31
ug/l
1.51
30
165
19
327
0.56
1.68
2.9
3.3
—
—
—
0
0
10
40
2.53
1.67
1.2
1.4
—
—
—
0
0
7
25
2.83
1.65
3.6
2.0
472.86
488.50
e6/l
—
7
20
35
230
1.56
1.65
4.5
2.8
5.57
5.87
kpa
1.16
35
224
28
174
1.65
1.65
1.3
2.0
—
—
—
0
0
21
121
1.77
1.61
4.1
8.5
—
—
—
0
0
39
265
1.51
1.59
4.4
3.1
—
—
—
0
0
65
488
1.38
1.58
3.2
2.4
5.22
4.60
e6/l
0.12
40
235
58
427
1.41
1.58
1.5
1.5
—
—
—
0
0
44
308
1.47
1.56
2.3
2.1
0.23
0.22
g/l
0.05
39
296
27
416
0.63
1.56
2.0
1.8
—
—
—
0
0
91
723
1.32
1.54
1.7
1.6
458.35
44000436.29
pmol/l
1.31
81
625
47
335
1.45
1.53
2.6
3.6
4.58
4.61
pmol/l
0.08
40
299
10
45
2.25
1.47
3.0
1.8
—
—
—
0
0
18
102
1.79
1.47
1.9
2.4
1.43
1.32
g/l
0.20
13
86
34
230
1.51
1.43
4.1
2.8
—
—
—
0
0
9
179
0.49
1.42
1.4
1.4
—
—
—
0
0
68
524
1.35
1.42
2.4
2.1
15.25
13.99
umol/l
0.69
62
492
14
74
1.92
1.40
1.1
1.2
164.86
246.89
u/ml
—
7
47
190
1672
1.22
1.37
3.8
2.9
5.73
5.89
ph
0.37
13
150
23
144
1.63
1.34
4.0
4.4
—
—
—
0
0
62
476
1.35
1.33
2.2
1.8
—
—
—
0
0
47
345
1.40
1.32
1.7
2.1
1240.58
3941.25
u/l
1.25
14
149
59
450
1.35
1.32
1.2
1.3
127.25
148.64
iu/ml
0.18
29
203
62
477
1.34
1.32
2.5
2.1
2.44
2.46
g/l
0.10
55
442
19
114
1.69
1.30
2.4
2.1
0.71
0.65
%
0.31
19
114
11
55
2.02
1.28
1.4
1.3
—
—
—
0
0
8
36
2.24
1.24
1.5
1.1
—
—
—
0
0
13
225
0.57
1.22
1.3
1.5
—
—
—
0
0
19
117
1.65
1.20
2.4
2.1
1.58
1.13
%
0.69
19
117
71
566
1.30
1.19
3.2
3.1
120.38
311.60
ng/l
0.57
47
331
12
64
1.90
1.19
1.1
1.1
—
—
—
0
0
13
223
0.57
1.18
1.3
1.5
—
—
—
0
0
13
222
0.57
1.17
1.3
1.5
—
—
—
0
0
0
34
0.00
1.16
0.0
1.3
—
68.41
—
0
34
284
2626
1.20
1.16
3.6
3.0
—
—
—
0
0
38
276
1.41
1.16
4.5
6.3
1.84
1.22
mmol/l
0.52
30
218
13
221
0.58
1.15
1.3
1.5
—
—
—
0
0
218
1970
1.19
1.15
2.4
2.3
—
—
—
0
0
73
589
1.28
1.12
2.4
2.2
120.10
94.06
ug/g
0.17
56
461
28
193
1.48
1.12
5.7
6.7
—
—
—
0
0
13
73
1.80
1.12
1.3
1.4
66.07
122.24
u/ml
—
5
17
12
206
0.57
1.11
1.3
1.5
—
—
—
0
0
91
757
1.25
1.09
3.7
3.5
—
—
—
0
0
55
430
1.31
1.07
2.8
2.2
25.80
23.10
%
0.66
44
366
155
1366
1.20
1.06
8.9
7.6
1.05
1.08
inr
0.35
41
443
7
33
2.14
1.06
1.7
1.5
—
—
—
0
0
29
204
1.45
1.06
1.3
1.3
2.12
0.86
u/ml
—
6
15
5
22
2.29
1.03
3.6
3.5
0.86
0.82
nmol/l
—
5
16
5
22
2.29
1.03
2.2
1.9
—
—
—
0
0
7
35
2.01
1.00
1.9
2.4
102.71
106.46
mmol/l
—
7
35
7
35
2.01
1.00
1.9
2.4
—
—
—
0
0
7
35
2.01
1.00
1.9
2.4
4.11
3.97
mmol/l
—
7
35
11
61
1.82
0.99
2.8
2.1
8.76
8.09
kpa
0.90
11
61
306
2872
1.18
0.97
2.9
2.7
39.94
35.87
u/l
0.41
290
2738
83
984
0.81
0.97
4.3
2.9
6.78
7.38
mmol/l
0.73
77
846
6
117
0.51
0.95
2.7
3.2
—
—
—
0
0
203
1847
1.17
0.94
6.6
5.3
0.67
0.68
%
0.16
186
1713
47
368
1.31
0.93
1.7
1.4
—
—
—
0
0
232
2138
1.16
0.91
6.3
5.5
0.17
0.17
e9/l
0.28
215
1912
5
102
0.48
0.90
1.4
1.6
—
—
—
0
0
6
30
2.01
0.87
1.8
1.8
63.67
62.67
%
—
6
30
447
4364
1.33
0.87
9.7
8.8
24.70
23.74
u/l
0.23
434
4240
8
44
1.83
0.86
2.0
1.9
—
—
—
0
0
6
31
1.95
0.84
7.3
3.0
—
—
—
0
0
8
45
1.79
0.84
1.3
2.0
—
—
—
0
0
23
163
1.43
0.83
3.9
2.9
—
—
—
0
0
117
1030
1.18
0.81
5.7
6.2
—
—
—
0
0
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
0
24
0.00
0.79
0.0
2.8
—
—
—
0
0
0
24
0.00
0.79
0.0
3.3
—
37125.21
—
0
24
0
25
0.00
0.79
0.0
1.2
—
25.82
—
0
25
13
82
1.60
0.78
1.3
1.1
—
12.50
—
0
9
107
939
1.18
0.77
4.2
2.5
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
14
206
0.67
0.73
1.0
1.1
—
—
—
0
0
5
25
2.01
0.73
1.0
1.0
—
—
—
0
0
5
25
2.01
0.73
11.6
3.4
—
—
—
0
0
5
26
1.93
0.71
1.6
1.2
—
—
—
0
0
7
120
0.58
0.68
15.6
5.8
—
—
—
0
0
31
241
1.31
0.68
1.7
2.3
—
—
—
0
0
112
999
1.16
0.66
1.9
1.7
—
—
—
0
0
29
370
0.77
0.66
1.1
1.4
—
—
—
0
0
67
575
1.19
0.63
1.9
1.5
—
—
—
0
0
10
63
1.60
0.62
1.1
1.4
—
75.08
—
0
5
49
582
0.82
0.61
1.2
1.3
—
—
—
0
0
299
2854
1.13
0.60
4.4
3.9
—
—
—
0
0
104
930
1.15
0.60
4.3
2.6
0.38
0.35
e6/l
0.05
80
681
0
22
0.00
0.59
0.0
3.4
—
—
—
0
0
62
532
1.19
0.59
1.3
1.2
—
—
—
0
0
425
4155
1.19
0.58
13.0
10.6
22.20
18.78
mg/l
1.21
331
3152
70
608
1.18
0.58
1.9
2.0
—
—
—
0
0
366
3541
1.14
0.58
4.6
4.4
14.37
14.39
pmol/l
0.05
347
3317
225
2120
1.11
0.56
6.4
5.2
1.89
1.98
e9/l
0.56
211
1922
164
1518
1.12
0.56
6.2
4.4
1.22
1.22
mmol/l
0.06
151
1396
81
716
1.16
0.55
4.1
2.2
9.22
8.85
e6/l
0.04
69
633
132
1208
1.13
0.54
3.3
2.8
—
—
—
0
0
11
74
1.50
0.54
5.9
4.3
—
—
—
0
0
11
157
0.69
0.52
1.0
1.2
—
—
—
0
0
131
1202
1.12
0.52
3.5
2.9
86.30
56.90
ng/l
0.17
55
622
206
1939
1.11
0.51
6.1
5.6
—
—
—
0
0
206
1939
1.11
0.51
6.7
5.5
8.07
7.96
%
0.25
191
1815
248
2357
1.11
0.51
8.2
8.2
3.96
3.90
e9/l
0.16
224
2080
13
92
1.42
0.51
8.8
3.2
—
—
—
0
0
76
674
1.15
0.50
3.6
2.5
495.86
517.44
mosm/kgh2o
0.43
65
573
51
438
1.18
0.50
1.4
1.3
—
—
—
0
0
107
973
1.13
0.49
1.6
1.7
0.71
0.85
mg/l
0.50
83
729
7
108
0.64
0.49
1.0
1.1
—
—
—
0
0
7
108
0.64
0.49
1.0
1.1
—
—
—
0
0
155
1663
0.90
0.49
2.5
2.4
—
—
—
0
0
36
301
1.21
0.47
2.9
4.1
13.97
8.12
ug/l
0.32
27
234
397
4056
0.88
0.46
3.8
3.7
4.84
4.86
mmol/l
0.18
383
3855
23
183
1.27
0.45
1.3
1.6
—
—
—
0
0
7
50
1.41
0.45
2.1
1.6
2.39
80.70
u/ml
—
7
50
111
1019
1.12
0.44
4.4
2.6
22.46
66.61
e6/l
1.69
84
754
204
1933
1.10
0.43
6.3
5.2
2.80
2.72
%
0.18
189
1806
11
78
1.42
0.43
1.3
1.2
—
—
—
0
0
348
3574
0.91
0.42
5.3
4.5
38.22
38.07
mmol/mol
0.11
328
3373
215
2046
1.09
0.41
6.3
5.2
0.52
0.52
e9/l
0.01
193
1809
219
2086
1.09
0.41
4.2
3.7
6.50
6.33
mmol/l
0.48
201
1885
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.7
—
—
—
0
0
211
2008
1.09
0.40
6.3
5.3
29.97
29.47
%
0.30
197
1888
8
60
1.34
0.40
1.8
4.3
34.29
24.33
mg/l
—
8
47
8
60
1.34
0.40
1.6
4.3
50.75
31.75
mg/l
—
8
48
0
18
0.00
0.40
0.0
1.9
—
—
—
0
0
13
97
1.35
0.40
1.6
1.9
—
—
—
0
0
383
3745
1.11
0.39
15.8
12.8
13.88
14.39
%
1.81
377
3695
0
19
0.00
0.39
0.0
1.2
—
30.32
—
0
19
0
19
0.00
0.39
0.0
2.3
—
506.23
—
0
13
23
188
1.23
0.38
1.9
2.8
63.72
74.71
e9/l
0.84
18
141
10
136
0.73
0.38
1.3
1.2
—
—
—
0
0
10
136
0.73
0.38
1.2
1.1
—
—
—
0
0
29
244
1.20
0.37
1.1
1.1
—
195.00
—
0
6
215
2054
1.08
0.37
6.2
5.2
0.04
0.04
e9/l
0.28
192
1813
44
385
1.16
0.37
1.6
1.3
—
—
—
0
0
403
4100
0.90
0.36
4.2
4.1
2.89
2.89
mmol/l
0.01
380
3879
397
4041
0.90
0.35
3.7
3.7
1.55
1.58
mmol/l
0.69
377
3827
63
569
1.12
0.34
1.7
1.6
1306.64
1185.95
nmol/l
0.48
56
432
10
74
1.36
0.32
1.8
2.1
—
—
—
0
0
6
47
1.28
0.32
1.2
1.1
—
—
—
0
0
7
53
1.33
0.31
1.3
2.2
—
—
—
0
0
14
111
1.27
0.30
2.9
3.1
0.32
0.22
g/l
—
7
35
207
1989
1.07
0.30
6.3
5.0
56.37
56.52
%
0.06
192
1865
21
248
0.84
0.28
1.5
1.5
—
—
—
0
0
10
76
1.32
0.28
1.3
1.8
6.29
5.08
mmol/24h
—
10
65
127
1341
0.93
0.28
1.7
1.6
—
—
—
0
0
5
74
0.67
0.26
2.8
1.4
—
—
—
0
0
74
795
0.92
0.25
1.6
1.7
—
—
—
0
0
83
887
0.92
0.25
4.9
3.7
10.36
7.32
mg/mmol
0.34
55
522
11
87
1.27
0.24
1.4
1.1
—
—
—
0
0
6
82
0.73
0.24
1.3
1.0
—
—
—
0
0
5
38
1.32
0.23
1.0
1.1
14.77
16.53
u/l
—
5
31
136
1300
1.06
0.23
4.8
3.1
67.61
60.00
e6/l
0.11
95
835
11
88
1.26
0.22
1.2
1.3
—
—
—
0
0
21
241
0.87
0.22
1.5
1.4
—
—
—
0
0
382
3872
0.94
0.21
3.3
3.3
1.23
1.20
mmol/l
0.50
363
3647
0
11
0.00
0.21
0.0
1.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
10.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
227
2207
1.05
0.21
3.0
2.8
85.73
68.38
ug/l
0.97
220
2088
385
3901
0.94
0.21
3.8
3.8
5.64
5.66
mmol/l
0.11
358
3645
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
58
624
0.92
0.21
2.1
2.4
2.41
2.43
mmol/l
1.08
49
555
0
13
0.00
0.21
0.0
2.1
—
1.36
—
0
13
174
1800
0.95
0.20
8.8
7.8
0.00
0.00
e9/l
1.28
148
1490
6
48
1.25
0.20
1.2
1.7
—
—
—
0
0
185
1791
1.05
0.20
2.5
2.2
75.77
76.30
nmol/l
0.08
171
1652
6
49
1.23
0.20
1.0
1.1
—
—
—
0
0
21
239
0.87
0.20
1.5
1.4
—
—
—
0
0
118
1129
1.06
0.19
1.2
1.3
0.56
1.90
u/ml
1.75
32
309
137
1424
0.95
0.19
1.8
1.8
90.53
99.21
pmol/l
1.34
72
743
7
63
1.11
0.17
2.1
2.7
—
—
—
0
0
26
234
1.12
0.17
4.2
5.3
1.25
1.21
mmol/l
0.09
26
227
57
535
1.07
0.16
1.1
1.1
—
—
—
0
0
6
76
0.79
0.15
1.3
1.4
—
—
—
0
0
9
80
1.13
0.15
1.4
1.2
—
—
—
0
0
19
169
1.13
0.15
2.4
2.3
—
—
—
0
0
7
87
0.80
0.14
1.9
3.5
4.00
4.41
e9/l
—
7
87
7
90
0.77
0.14
1.9
3.9
59.14
58.48
%
—
7
90
40
373
1.08
0.14
4.0
3.5
—
—
—
0
0
122
1180
1.05
0.14
2.1
1.9
—
—
—
0
0
26
284
0.91
0.14
2.5
4.2
0.00
0.15
%
—
5
65
464
4659
0.90
0.12
18.6
16.0
30.16
30.06
pg
0.71
459
4613
82
790
1.05
0.11
1.5
1.4
23.80
21.90
nmol/l
0.53
71
686
29
311
0.93
0.11
2.3
4.1
0.69
1.18
%
—
8
92
464
4656
0.91
0.09
18.5
16.0
39.62
39.69
%
0.12
432
4436
21
194
1.09
0.09
1.3
1.3
—
—
—
0
0
6
54
1.11
0.09
1.2
1.4
—
—
—
0
0
6
56
1.07
0.08
1.7
2.6
32.17
32.49
umol/l
—
6
49
464
4655
0.92
0.08
18.7
16.1
265.81
266.37
e9/l
0.06
457
4572
28
263
1.07
0.08
1.4
1.2
—
—
—
0
0
105
1024
1.03
0.08
1.8
1.6
1.33
1.35
mmol/l
0.11
92
892
6
58
1.03
0.08
1.3
1.9
—
—
—
0
0
5
61
0.82
0.08
1.0
1.2
—
—
—
0
0
26
244
1.07
0.08
1.1
1.1
—
—
—
0
0
27
286
0.94
0.07
2.4
3.9
0.71
0.94
%
—
7
75
82
841
0.97
0.07
4.4
3.1
70.48
214.92
mg/l
0.58
57
511
9
100
0.90
0.06
6.9
4.0
—
—
—
0
0
28
294
0.95
0.06
2.4
4.2
0.00
0.15
%
—
7
75
35
336
1.04
0.05
3.5
2.1
37.81
31.49
u/l
0.56
27
279
33
317
1.04
0.05
1.2
1.2
—
—
—
0
0
23
241
0.95
0.04
1.7
1.3
269.49
251.63
miu/ml
—
10
121
465
4660
0.94
0.04
18.7
16.2
132.38
132.88
g/l
0.43
460
4614
465
4660
0.94
0.04
18.6
16.1
6.69
6.61
e9/l
0.38
455
4559
20
190
1.05
0.04
1.7
1.7
—
—
—
0
0
46
448
1.03
0.03
1.4
1.3
—
—
—
0
0
465
4659
0.95
0.03
18.6
16.1
4.40
4.44
e12/l
1.53
456
4563
97
957
1.02
0.03
1.4
1.4
2.62
2.17
g/l
1.42
61
611
10
92
1.09
0.03
1.0
1.8
—
—
—
0
0
403
4041
0.98
0.02
5.2
5.1
1.73
2.04
mu/l
0.55
382
3811
93
941
0.99
0.02
2.3
2.0
2.77
2.83
mg/l
0.11
83
815
465
4658
0.95
0.02
18.5
16.0
90.72
90.42
fl
0.81
460
4613
440
4407
0.98
0.01
11.5
10.0
—
—
—
0
0
86
867
0.99
0.01
2.5
2.1
297.00
5702.64
umol/l
3.68
73
782
127
1263
1.01
0.01
2.6
3.1
2.33
2.36
mmol/l
1.06
121
1150
124
1246
0.99
0.00
2.1
1.9
—
—
—
0
0
39
385
1.01
0.00
1.1
1.2
—
—
—
0
0
27
273
0.99
0.00
2.6
3.6
1.22
1.23
mmol/l
0.96
22
235
10
101
0.99
0.00
1.1
1.4
3.26
3.66
mmol/l
—
10
92
63
631
1.00
0.00
1.4
1.4
—
—
—
0
0
407
4069
1.00
0.00
13.4
10.7
139.37
139.65
mmol/l
1.29
398
3958
408
4084
0.99
0.00
13.5
10.7
3.90
3.91
mmol/l
0.11
399
3962
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
15.93
—
0
5
0
6
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
132.66
—
0
9
13
130
1.00
-0.00
1.1
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
7
71
0.99
-0.00
1.4
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
16.88
—
0
5
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.1
—
—
—
0
0
20
200
1.00
-0.00
13.0
6.5
8.80
7.39
mmol/l
0.41
20
190
5
59
0.85
-0.00
1.0
1.2
—
—
—
0
0
8
83
0.96
-0.00
1.0
1.1
—
—
—
0
0
6
69
0.87
-0.00
1.3
1.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint N14_FEMALE_GENITAL_DYSPLASIA_NOS and mortality.

Females

Parameter HR [95% CI] p-value
N14_FEMALE_GENITAL_DYSPLASIA_NOS 1.288 [1.06, 1.57] 0.012
Birth year 0.995 [0.99, 1.0] 0.254

During the follow-up period (1.1.1998 — 31.12.2019), 177 out of 2382 females with N14_FEMALE_GENITAL_DYSPLASIA_NOS died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_FEMALE_GENITAL_DYSPLASIA_NOS.

N-year risk Females Males
1 0.127% No data
5 0.817% No data
10 2.041% No data
15 3.893% No data
20 6.818% No data

Relationships between endpoints

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Index endpoint: N14_FEMALE_GENITAL_DYSPLASIA_NOS – Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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