Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva

N14_FEMALE_GENITAL_DYSPLASIA_NOS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

461

4. Check minimum number of events

None

461

5. Include endpoints

None

461

6. Filter based on genotype QC (FinnGen only)

461

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF7

Similar endpoints

List of similar endpoints to Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2793 2793 -
Only index persons 2743 2743 -
Unadjusted period prevalence (%)
Whole population 0.08 0.08 -
Only index persons 0.10 0.10 -
Median age at first event (years)
Whole population - 41.62 -
Only index persons - 41.33 -

-FinnGen-

Key figures

All Female Male
Number of individuals 461 461 -
Unadjusted period prevalence (%) 0.16 0.16 -
Median age at first event (years) 43.10 43.10 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
412
Matched controls
4120
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N87.9
ICD-10 Finland
Dysplasia of cervix uteri, unspecified
5895.5
323.0
339
*
ULA02
NOMESCO Finland
Kolposcopy
20.9
157.4
288
411
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
14.5
107.5
208
270
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
16.4
93.5
163
158
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
10.4
92.5
224
424
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
9.9
91.2
230
465
LDA10
NOMESCO Finland
Curettage of cervix uteri
11.4
59.9
121
145
N87.0
ICD-10 Finland
Mild cervical dysplasia
12.9
45.0
83
79
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
12.8
42.3
78
74
N90.3
ICD-10 Finland
Dysplasia of vulva, unspecified
+∞
41.3
39
*
N89.3
ICD-10 Finland
Dysplasia of vagina, unspecified
+∞
37.0
35
*
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
14.2
33.0
57
46
N87.1
ICD-10 Finland
Moderate cervical dysplasia
8.2
25.1
58
81
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
2.7
20.5
232
1334
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
7.8
18.9
44
62
A63.0
ICD-10 Finland
Anogenital (venereal) warts
5.2
17.1
55
119
LEB00
NOMESCO Finland
Biopsy of vagina
7.3
14.6
35
52
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
51.7
12.9
15
*
LFC00
NOMESCO Finland
Partial excision of vulva
26.8
9.9
13
5
R87.9
ICD-10 Finland
Abnormal findings in specimens from female genital organs, unspecified abnormal finding
22.3
9.4
13
6
LCA06
NOMESCO Finland
Biopsy of endometrium
2.3
9.1
90
440
D06.0
ICD-10 Finland
Carcinoma in situ: Endocervix
24.6
9.0
12
5
N90.0
ICD-10 Finland
Mild vulvar dysplasia
22.5
8.1
11
5
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
45.9
7.7
9
*
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
8.1
7.2
15
19
P01AB01
ATC
metronidazole; oral, rectal
1.8
7.1
196
1403
ZXC00
NOMESCO Finland
Use of diathermy
9.0
7.1
14
16
SPAT1193
SPAT
Pap smear
2.1
6.8
78
406
WX702
NOMESCO Finland
Supraglottic ventilation device
3.2
6.8
34
112
8140/2-C53.9
ICD-O-3
Adenocarcinoma in situ, NOS, of cervix uteri
22.9
6.7
9
*
X86
ICPC
Abnormal cervix smear
6.4
6.5
16
26
8071/2-C51.9
ICD-O-3
Differentiated intraepithelial neoplasia of vulva, NOS
70.9
6.4
7
*
LCD31
NOMESCO Finland
Radical laparoscopic hysterectomy
27.1
6.2
8
*
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
27.1
6.2
8
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
96
118
10.01
75.50
2.3
1.8
—
—
—
0
0
177
1381
1.46
3.65
4.0
4.0
35.9
36.6
g/l
1.06
167
1286
19
77
2.53
3.34
1.7
2.0
13.0
13.3
%
0.61
19
77
213
1748
1.41
3.22
2.9
2.0
—
—
—
0
0
145
1113
1.44
3.18
2.6
2.2
54.5
56.4
u/l
0.33
135
1039
90
628
1.54
3.16
1.4
1.4
642.2
563.3
titre
0.10
18
144
235
1966
1.40
3.16
3.6
3.2
0.0
0.0
estimate
0.80
46
377
231
1930
1.39
3.11
3.7
3.2
0.0
0.0
estimate
0.00
45
379
50
307
1.71
2.95
1.4
1.4
—
—
—
0
0
112
831
1.46
2.92
3.7
3.3
1.0
1.0
kg/l
1.10
18
108
231
1944
1.38
2.91
5.0
4.4
0.0
0.0
estimate
0.50
45
387
60
390
1.62
2.85
2.0
2.2
5.2
5.2
umol/l
0.00
47
335
111
827
1.45
2.82
1.3
1.3
17.5
29.4
iu/ml
1.33
41
292
15
63
2.43
2.49
1.0
1.1
—
—
—
0
0
127
991
1.39
2.47
4.2
3.4
7.4
7.4
ph
1.16
13
190
196
1638
1.34
2.46
5.2
5.2
1.2
1.2
mmol/l
0.01
170
1383
131
1031
1.38
2.41
3.8
3.4
0.0
0.0
estimate
1.08
45
387
38
236
1.66
2.19
1.5
1.4
—
—
—
0
0
27
152
1.82
2.17
1.1
1.2
—
—
—
0
0
109
848
1.37
2.14
3.7
3.1
—
—
—
0
0
321
2917
1.33
2.10
4.1
3.9
10.2
10.1
mm/h
0.10
301
2719
65
887
0.69
2.07
2.5
3.0
—
—
—
0
0
214
1852
1.29
1.97
4.9
5.3
10.0
9.4
umol/l
0.59
201
1745
43
284
1.57
1.96
2.0
2.2
0.2
0.2
g/l
0.03
38
272
24
398
0.58
1.85
2.1
1.8
—
—
—
0
0
312
2847
1.30
1.85
7.2
6.6
72.3
74.1
u/l
0.41
294
2675
47
322
1.51
1.83
2.6
3.6
4.6
4.6
pmol/l
0.07
40
287
34
216
1.62
1.82
4.2
3.0
2.1
2.3
mmol/l
0.23
27
171
7
168
0.41
1.82
1.4
1.4
—
—
—
0
0
89
689
1.36
1.80
1.7
1.6
455.8
46218925.0
pmol/l
1.31
79
595
21
117
1.83
1.77
4.1
8.5
—
—
—
0
0
36
235
1.58
1.74
1.7
1.7
1.3
1.4
g/l
0.31
31
216
6
19
3.19
1.66
1.2
1.2
—
—
—
0
0
7
25
2.83
1.65
3.6
2.0
472.9
488.5
e6/l
—
7
20
136
1132
1.29
1.65
3.0
2.5
—
—
—
0
0
103
826
1.32
1.64
1.3
1.3
21.2
15.2
u/ml
0.22
38
349
18
310
0.56
1.61
3.0
3.4
—
—
—
0
0
11
214
0.50
1.47
1.3
1.4
—
—
—
0
0
11
52
2.14
1.45
1.4
1.4
—
—
—
0
0
12
59
2.06
1.44
1.1
1.1
—
—
—
0
0
11
212
0.51
1.44
1.3
1.4
—
—
—
0
0
28
181
1.58
1.43
3.3
2.4
2.6
4.5
ug/l
1.15
28
159
174
1514
1.24
1.42
3.7
3.0
—
—
—
0
0
11
211
0.51
1.42
1.3
1.4
—
—
—
0
0
11
211
0.51
1.42
1.3
1.4
—
—
—
0
0
9
40
2.27
1.41
1.2
1.4
—
—
—
0
0
12
60
2.03
1.39
1.4
1.8
0.8
0.7
g/l
—
7
44
54
403
1.39
1.38
1.4
1.5
—
—
—
0
0
10
196
0.50
1.38
1.3
1.4
—
—
—
0
0
57
430
1.37
1.37
1.2
1.2
119.9
152.2
iu/ml
0.29
28
193
44
318
1.42
1.35
1.8
2.1
1335.9
3848.6
u/l
1.00
13
134
26
168
1.58
1.34
1.3
2.0
—
—
—
0
0
32
219
1.50
1.30
4.4
2.9
5.6
5.9
kpa
1.15
32
213
64
498
1.33
1.27
2.3
2.1
15.4
13.9
umol/l
0.76
57
463
32
221
1.48
1.25
3.9
2.9
—
—
—
0
0
8
36
2.24
1.25
1.5
1.0
—
—
—
0
0
36
255
1.45
1.24
4.4
3.1
—
—
—
0
0
59
458
1.33
1.20
1.9
1.9
—
—
—
0
0
68
539
1.31
1.20
3.2
3.1
128.1
164.7
ng/l
0.12
44
317
58
451
1.33
1.17
2.3
2.1
2.4
2.5
g/l
0.12
51
420
0
33
0.00
1.16
0.0
1.3
—
65.8
—
0
5
5
113
0.44
1.14
1.8
3.3
—
—
—
0
0
18
111
1.65
1.13
2.4
2.2
1.6
1.1
%
0.71
18
111
7
31
2.28
1.10
1.1
1.2
—
—
—
0
0
88
729
1.26
1.10
3.5
3.5
—
—
—
0
0
28
195
1.46
1.07
1.4
1.3
2.1
0.9
u/ml
—
6
15
272
2522
1.19
1.07
3.6
3.0
—
—
—
0
0
52
405
1.32
1.05
2.6
2.2
26.1
22.8
%
0.79
41
345
5
22
2.29
1.03
2.2
1.9
—
—
—
0
0
7
34
2.07
1.03
1.9
2.4
102.7
106.5
mmol/l
—
7
34
7
34
2.07
1.03
1.9
2.4
4.1
3.9
mmol/l
—
7
34
7
34
2.07
1.03
1.9
2.4
—
—
—
0
0
130
1132
1.21
1.02
6.5
5.6
1.0
1.1
inr
0.87
38
373
5
23
2.19
0.98
1.0
1.0
—
—
—
0
0
5
23
2.19
0.98
1.0
1.1
—
—
—
0
0
69
565
1.26
0.96
2.4
2.2
128.0
96.5
ug/g
0.20
52
442
194
1762
1.17
0.94
6.3
5.4
0.7
0.7
%
0.23
179
1634
21
142
1.50
0.94
4.1
4.3
—
—
—
0
0
26
184
1.44
0.94
5.8
6.7
—
—
—
0
0
6
27
2.24
0.93
1.8
1.9
63.7
60.9
%
—
6
27
79
935
0.81
0.92
4.0
2.9
6.8
7.5
mmol/l
0.78
71
790
6
28
2.16
0.92
7.3
2.7
—
—
—
0
0
8
42
1.92
0.89
1.3
2.1
—
—
—
0
0
8
42
1.92
0.89
2.0
2.0
—
—
—
0
0
205
1877
1.17
0.88
4.2
3.8
—
—
—
0
0
13
80
1.64
0.85
1.3
1.5
—
—
—
0
0
13
81
1.62
0.82
1.3
1.1
—
12.5
—
0
9
35
269
1.33
0.80
4.5
6.3
1.7
1.3
mmol/l
0.29
28
210
129
1147
1.17
0.80
3.1
2.8
—
—
—
0
0
0
24
0.00
0.79
0.0
2.0
—
—
—
0
0
0
24
0.00
0.79
0.0
1.2
—
26.5
—
0
24
0
27
0.00
0.77
0.0
2.7
—
48.2
—
0
15
13
197
0.65
0.77
1.0
1.1
—
—
—
0
0
16
232
0.68
0.77
1.6
1.5
—
—
—
0
0
220
2042
1.15
0.76
6.1
5.6
0.2
0.2
e9/l
0.83
206
1832
390
3778
1.21
0.75
13.9
11.6
39.5
39.5
%
0.05
308
3023
38
300
1.29
0.73
5.0
5.4
103.7
104.3
mmol/l
0.37
38
292
5
25
2.01
0.73
1.6
1.2
—
—
—
0
0
5
25
2.01
0.73
12.4
3.6
—
—
—
0
0
360
3471
1.17
0.69
15.1
13.0
13.4
13.5
%
0.83
354
3417
5
93
0.53
0.67
1.4
1.6
—
—
—
0
0
111
989
1.16
0.67
5.7
6.3
—
—
—
0
0
16
225
0.70
0.67
1.6
1.4
—
—
—
0
0
7
44
1.60
0.65
2.1
2.1
—
—
—
0
0
68
583
1.20
0.65
1.8
2.0
—
—
—
0
0
16
223
0.71
0.64
1.6
1.4
—
—
—
0
0
104
926
1.16
0.64
1.6
1.8
0.7
0.8
mg/l
0.42
80
696
378
3884
0.85
0.63
3.7
3.8
4.8
4.9
mmol/l
0.20
366
3682
6
103
0.58
0.62
1.0
1.1
—
—
—
0
0
6
103
0.58
0.62
1.0
1.1
—
—
—
0
0
11
71
1.56
0.62
5.9
4.3
—
—
—
0
0
47
561
0.82
0.62
1.2
1.3
—
—
—
0
0
13
88
1.49
0.61
9.2
3.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
3.4
—
—
—
0
0
0
23
0.00
0.58
0.0
2.7
—
—
—
0
0
7
116
0.60
0.58
15.6
5.4
—
—
—
0
0
284
2711
1.12
0.58
4.4
4.0
—
—
—
0
0
6
35
1.72
0.58
1.5
1.3
—
—
—
0
0
6
35
1.72
0.58
1.5
1.3
—
—
—
0
0
6
35
1.72
0.58
1.5
1.3
—
—
—
0
0
6
35
1.72
0.58
1.5
1.3
—
—
—
0
0
21
159
1.34
0.56
4.2
2.9
—
—
—
0
0
349
3378
1.14
0.55
4.5
4.4
14.4
14.4
pmol/l
0.07
331
3162
11
74
1.50
0.54
1.2
1.2
164.0
245.0
u/ml
—
6
47
42
351
1.22
0.54
1.8
1.4
—
—
—
0
0
157
1454
1.12
0.53
5.0
4.5
1.2
1.2
mmol/l
0.03
143
1329
29
233
1.26
0.52
1.1
1.1
—
195.0
—
0
6
33
270
1.24
0.51
1.9
2.8
1.8
1.8
%
0.03
33
240
72
635
1.16
0.51
3.4
2.4
504.9
529.2
mosm/kgh2o
0.45
60
534
10
145
0.68
0.51
1.0
1.2
—
—
—
0
0
378
3870
0.87
0.51
3.7
3.7
1.5
1.6
mmol/l
0.96
360
3657
35
290
1.22
0.49
3.0
4.0
14.4
8.2
ug/l
0.33
26
228
99
897
1.13
0.48
4.2
2.5
—
—
—
0
0
7
46
1.53
0.48
2.1
1.6
2.4
100.8
u/ml
—
7
38
196
1847
1.11
0.48
6.5
5.5
8.1
8.0
%
0.28
183
1729
7
47
1.50
0.47
1.9
2.1
—
—
—
0
0
405
3970
1.17
0.47
12.4
10.7
22.4
18.8
mg/l
1.25
314
3011
195
1842
1.10
0.45
6.1
5.3
2.7
2.7
%
0.09
181
1712
9
128
0.70
0.44
1.2
1.1
—
—
—
0
0
213
2024
1.10
0.43
6.2
5.3
1.9
2.0
e9/l
0.44
197
1821
125
1158
1.11
0.42
3.1
2.9
89.8
58.0
ng/l
0.17
52
602
210
1996
1.10
0.42
3.6
3.8
6.5
6.3
mmol/l
0.37
192
1805
118
1274
0.90
0.42
1.8
1.6
—
—
—
0
0
42
362
1.18
0.41
1.7
1.3
—
—
—
0
0
201
1909
1.09
0.41
6.0
5.4
30.1
29.5
%
0.34
188
1777
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
3.4
—
—
—
0
0
235
2248
1.09
0.41
8.1
8.3
3.9
3.9
e9/l
0.13
214
1985
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
385
3924
0.89
0.40
4.1
4.1
2.9
2.9
mmol/l
0.05
363
3701
58
514
1.15
0.40
1.3
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.9
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
30.8
—
0
18
0
19
0.00
0.39
0.0
2.3
—
506.2
—
0
13
29
344
0.83
0.39
1.1
1.4
—
—
—
0
0
10
136
0.73
0.38
1.3
1.2
—
—
—
0
0
10
72
1.40
0.37
1.8
2.0
—
—
—
0
0
48
423
1.15
0.37
1.4
1.3
—
—
—
0
0
28
236
1.20
0.36
1.7
2.3
—
—
—
0
0
60
539
1.13
0.35
1.7
1.6
1292.9
1189.7
nmol/l
0.38
54
410
96
887
1.10
0.35
4.4
2.6
0.4
0.3
e6/l
0.06
75
648
6
45
1.34
0.34
1.2
1.7
—
—
—
0
0
6
45
1.34
0.34
1.0
1.1
—
—
—
0
0
101
939
1.10
0.33
1.8
1.7
—
—
—
0
0
61
552
1.12
0.32
1.8
1.5
—
—
—
0
0
11
83
1.33
0.32
1.4
1.1
—
—
—
0
0
67
733
0.90
0.32
1.6
1.7
—
—
—
0
0
75
690
1.10
0.30
3.4
2.3
9.8
9.1
e6/l
0.08
61
600
10
75
1.34
0.30
1.3
1.2
—
—
—
0
0
12
152
0.78
0.30
1.1
2.5
0.8
0.1
e6/l
0.52
12
145
197
1891
1.07
0.29
6.1
5.1
56.1
56.5
%
0.22
184
1771
7
57
1.23
0.29
1.7
4.4
36.8
24.4
mg/l
—
7
44
7
57
1.23
0.29
1.6
4.4
55.5
32.2
mg/l
—
7
45
104
975
1.09
0.29
3.9
2.7
23.1
65.3
e6/l
1.49
80
722
39
346
1.14
0.29
4.1
3.3
—
—
—
0
0
11
85
1.30
0.28
1.5
1.7
—
—
—
0
0
21
177
1.20
0.28
1.9
2.9
65.9
76.1
e9/l
0.68
16
132
128
1212
1.08
0.28
6.3
5.3
—
—
—
0
0
203
1956
1.07
0.27
6.0
5.3
0.5
0.5
e9/l
0.02
184
1728
21
178
1.19
0.26
1.3
1.6
—
—
—
0
0
5
72
0.69
0.26
2.8
1.4
—
—
—
0
0
365
3709
0.92
0.26
3.2
3.4
1.2
1.2
mmol/l
0.60
347
3491
442
4450
0.84
0.26
18.0
16.1
30.2
30.1
pg
0.75
437
4404
368
3737
0.92
0.25
3.8
3.8
5.6
5.7
mmol/l
0.10
342
3489
165
1715
0.94
0.23
8.9
7.7
0.0
0.0
e9/l
1.28
140
1416
5
39
1.29
0.23
1.0
1.1
14.8
16.2
u/l
—
5
32
203
1966
1.06
0.22
6.1
5.3
0.0
0.0
e9/l
0.37
182
1731
0
11
0.00
0.21
0.0
10.5
—
—
—
0
0
0
10
0.00
0.21
0.0
2.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
152
1579
0.94
0.21
2.3
2.4
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.2
—
1.4
—
0
12
442
4446
0.86
0.20
18.1
16.3
267.0
266.6
e9/l
0.04
435
4364
79
744
1.07
0.20
1.5
1.4
24.1
22.0
nmol/l
0.56
69
644
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
80
846
0.93
0.19
4.6
3.8
10.6
7.2
mg/mmol
0.37
52
499
6
51
1.18
0.19
1.3
2.1
—
—
—
0
0
337
3420
0.95
0.19
5.0
4.6
38.0
38.1
mmol/mol
0.11
319
3226
113
1082
1.06
0.18
1.2
1.3
0.6
1.9
u/ml
1.66
30
298
20
225
0.88
0.16
1.8
1.3
266.1
246.7
miu/ml
—
9
114
443
4452
0.87
0.16
18.1
16.3
6.7
6.6
e9/l
0.44
433
4353
6
79
0.76
0.15
6.8
3.1
3.4
3.7
mmol/l
—
6
70
6
80
0.75
0.15
1.3
1.0
—
—
—
0
0
443
4451
0.88
0.15
18.1
16.3
132.5
132.9
g/l
0.33
438
4406
9
81
1.11
0.15
1.1
1.3
—
—
—
0
0
7
87
0.80
0.14
1.9
3.9
59.1
58.8
%
—
7
87
443
4450
0.88
0.14
18.1
16.2
4.4
4.4
e12/l
1.35
434
4357
12
103
1.17
0.14
7.2
2.8
24.0
24.2
mmol/l
0.16
12
96
8
96
0.83
0.14
7.4
3.7
—
—
—
0
0
80
835
0.95
0.13
2.2
2.1
298.4
5971.0
umol/l
3.68
67
745
131
1350
0.96
0.13
1.8
1.8
90.7
99.2
pmol/l
1.22
69
702
443
4449
0.89
0.13
18.0
16.2
90.7
90.4
fl
0.80
438
4404
62
591
1.06
0.12
1.4
1.4
—
—
—
0
0
20
181
1.11
0.12
1.7
1.7
—
—
—
0
0
124
1205
1.04
0.12
2.5
3.1
2.3
2.4
mmol/l
0.89
117
1088
12
106
1.14
0.10
2.9
3.2
0.1
0.3
g/l
—
6
34
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
213
2097
1.03
0.09
3.0
2.8
87.8
68.0
ug/l
1.08
206
1982
10
87
1.15
0.09
1.0
1.9
—
—
—
0
0
6
55
1.09
0.09
1.3
1.9
—
—
—
0
0
5
60
0.83
0.08
1.0
1.2
—
—
—
0
0
116
1186
0.97
0.08
2.0
2.0
—
—
—
0
0
32
303
1.06
0.08
1.2
1.2
—
—
—
0
0
7
67
1.05
0.08
1.4
1.3
—
—
—
0
0
6
72
0.83
0.07
2.0
1.1
—
—
—
0
0
6
73
0.82
0.07
1.3
1.4
—
—
—
0
0
57
590
0.96
0.07
2.2
2.4
2.4
2.4
mmol/l
1.04
48
525
53
511
1.04
0.07
1.2
1.1
—
—
—
0
0
7
84
0.83
0.07
1.9
3.5
4.0
4.5
e9/l
—
7
84
100
982
1.02
0.05
1.8
1.6
1.3
1.4
mmol/l
0.10
89
855
27
258
1.05
0.05
2.6
3.6
1.2
1.2
mmol/l
0.97
22
224
79
806
0.98
0.04
4.1
3.1
72.7
221.0
mg/l
0.57
54
491
13
121
1.08
0.03
4.9
7.4
23.4
24.1
mmol/l
0.67
13
115
26
250
1.04
0.03
1.3
1.2
—
—
—
0
0
420
4210
0.97
0.03
11.3
10.1
—
—
—
0
0
103
1018
1.02
0.02
3.4
4.1
—
—
—
0
0
23
222
1.04
0.02
4.3
5.3
1.2
1.2
mmol/l
0.06
23
212
91
920
0.99
0.02
1.5
1.4
2.7
2.2
g/l
1.59
57
584
125
1240
1.01
0.02
4.4
3.2
62.1
62.7
e6/l
0.01
90
804
44
432
1.02
0.01
1.4
1.3
—
—
—
0
0
17
163
1.04
0.01
2.5
2.3
—
—
—
0
0
18
186
0.97
0.00
1.2
1.3
—
—
—
0
0
385
3856
0.99
0.00
5.2
5.1
1.7
2.0
mu/l
0.54
365
3633
112
1114
1.01
0.00
2.1
1.9
—
—
—
0
0
10
97
1.03
0.00
1.1
1.4
3.3
3.7
mmol/l
—
10
88
19
194
0.98
0.00
8.4
7.1
8.5
7.5
mmol/l
0.24
19
184
390
3902
1.00
0.00
12.8
10.8
3.9
3.9
mmol/l
0.22
381
3783
89
892
1.00
0.00
2.3
2.0
2.7
2.8
mg/l
0.32
81
771
37
371
1.00
0.00
1.1
1.2
—
—
—
0
0
389
3887
1.00
0.00
12.7
10.8
139.4
139.7
mmol/l
1.24
380
3779
5
58
0.86
0.00
1.0
1.2
—
—
—
0
0
6
65
0.92
0.00
1.3
1.8
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
51
0.98
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
132.7
—
0
9
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
23
230
1.00
0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
4.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
6
60
1.00
0.00
2.2
2.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
7
78
0.90
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
8
80
1.00
0.00
1.5
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
16.9
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
15.9
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
6.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint N14_FEMALE_GENITAL_DYSPLASIA_NOS and mortality.

Females

Parameter HR [95% CI] p-value
N14_FEMALE_GENITAL_DYSPLASIA_NOS 1.288 [1.06, 1.57] 0.012
Birth year 0.995 [0.99, 1.0] 0.254

During the follow-up period (1.1.1998 — 31.12.2019), 177 out of 2382 females with N14_FEMALE_GENITAL_DYSPLASIA_NOS died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have N14_FEMALE_GENITAL_DYSPLASIA_NOS.

N-year risk Females Males
1 0.127% No data
5 0.817% No data
10 2.041% No data
15 3.893% No data
20 6.818% No data

Relationships between endpoints

Index endpoint: N14_FEMALE_GENITAL_DYSPLASIA_NOS – Dysplastic lesion of unknown severity in the cervix uteri, vagina or vulva

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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