Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

CD2_BENIGN_LIPO_SKIN_HEADFACENECK

lipoma: A benign, usually painless, well-circumscribed lipomatous tumor composed of adipose tissue.

Suggest a new description

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D17.0&
  • Cause of death: ICD-10 D17.0&

2 out of 7 registries used, show all original rules.

2609

4. Check minimum number of events

None

2609

5. Include endpoints

None

2609

6. Filter based on genotype QC (FinnGen only)

2511

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D17
Name in latin
Neoplasma benignum lipomatosum cutis capitis/colli/nuchae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17408 7349 9961
Only index persons 16692 7138 9554
Unadjusted period prevalence (%)
Whole population 0.25 0.21 0.28
Only index persons 0.32 0.26 0.36
Median age at first event (years)
Whole population 53.92 54.12 53.85
Only index persons 53.72 53.94 53.56

-FinnGen-

Key figures

All Female Male
Number of individuals 2511 1168 1343
Unadjusted period prevalence (%) 0.52 0.41 0.62
Median age at first event (years) 56.93 54.92 58.68

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2609
Matched controls
26090
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
+∞
307.7
2609
40
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
11.6
307.7
374
370
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
14.1
307.7
1046
1185
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
7.2
307.7
564
963
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
10.4
197.7
227
236
D17.9
ICD-10 Finland
Benign lipomatous neoplasm, unspecified
12.5
153.0
153
129
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
6.5
149.5
260
439
D17
ICD-10 Finland
Benign lipomatous neoplasm
11.9
131.0
135
119
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
56.4
116.7
66
12
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
7.0
84.8
133
200
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
6.2
79.8
139
233
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
8.3
68.9
92
115
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
4.3
55.1
147
357
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
15.9
54.7
47
30
L72.1
ICD-10 Finland
Trichilemmal cyst
2.9
50.0
252
924
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.3
46.3
121
289
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
5.0
40.9
89
183
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.6
40.3
262
1091
S78
ICPC
Lipoma
8.0
38.4
52
66
S04
ICPC
Lump/swelling localized
2.3
34.6
299
1412
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.6
34.1
115
330
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.7
34.0
191
739
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
10.8
30.5
33
31
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
4.6
30.2
72
160
WX110
NOMESCO Finland
Infiltration anesthesia
1.7
30.2
1825
15204
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.8
28.9
89
240
S18
ICPC
Laceration/cut
1.6
28.5
1205
9157
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
23.6
156
653
SPAT1153
SPAT
Removal of sutures
1.6
23.4
828
5967
ZXA00
NOMESCO Finland
Right side
1.5
17.8
660
4756
N02AX02
ATC
tramadol; systemic, rectal
1.4
17.7
1082
8595
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
16.9
914
7081
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.3
16.7
64
200
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
5.1
16.0
33
65
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
5.2
15.8
32
62
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
15.4
629
4603
M01AE01
ATC
ibuprofen; systemic, rectal
1.6
15.1
2273
21042
ZXD20
NOMESCO Finland
Day surgery
1.7
14.8
309
1939
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.6
14.7
83
322
N02BE01
ATC
paracetamol; systemic, rectal
1.6
14.6
2244
20744
J01DB01
ATC
cefalexin; oral
1.5
14.5
2057
18672
M03BX02
ATC
tizanidine; oral
1.4
14.5
1523
13113
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.5
14.5
94
391
ZXA05
NOMESCO Finland
Left side
1.5
14.4
594
4346
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
14.2
1091
8914
D17.7
ICD-10 Finland
Benign lipomatous neoplasm of other sites
10.5
13.7
26
25
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.4
13.3
1325
11241
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
13.3
1722
15232
QX3HE, ,
SPAT
3.1
13.1
53
172
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
11.2
1476
12917
D23.4
ICD-10 Finland
Benign neoplasm: Skin of scalp and neck
3.3
11.1
40
121
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
11.1
836
6742
B01AB05
ATC
enoxaparin; parenteral
1.4
10.9
730
5772
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
15.5
10.8
17
11
UJF32
NOMESCO Finland
Coloscopy
1.4
10.6
608
4689
Z2221
NOMESCO Finland
Medical doctor
1.4
10.4
602
4645
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
10.3
851
6936
KMAK, ,
NOMESCO Finland
1.3
10.3
1172
10000
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
10.3
452
3327
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
10.2
499
3741
R03AC02
ATC
salbutamol; inhalant
1.3
10.2
1258
10848
ZXE00
NOMESCO Finland
One hour or less
1.3
10.1
872
7152
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
10.0
1000
8366
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
4.6
10.0
23
50
ENB99
NOMESCO Finland
Other excision of pharynx and adjacent structures
26.1
9.8
13
5
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
9.8
943
7849
C08CA01
ATC
amlodipine; oral
1.3
9.7
901
7456
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.6
1521
13512
SFA20
NOMESCO Finland
Two-surface restoration
1.3
9.6
1366
11966
QBJ00
NOMESCO Finland
Liposuction in trunk
5.0
9.6
20
40
M79.6
ICD-10 Finland
Pain in limb
1.3
9.5
948
7917
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
9.3
245
1622
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
9.3
518
3966
R01AD09
ATC
mometasone; nasal
1.3
9.3
1005
8479
G47.3
ICD-10 Finland
Sleep apnoea
1.4
9.1
563
4383
WX002
NOMESCO Finland
Sedation and analgesia
1.4
9.0
441
3301
SPAT1263
SPAT
Sampling
1.3
9.0
915
7651
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.9
1070
9135
E66.8
ICD-10 Finland
Other obesity
1.8
8.9
121
671
M54.5
ICD-10 Finland
Low back pain
1.3
8.9
798
6554
A98
ICPC
Health maint/preventive medicine
1.7
8.9
2475
23849
N03AX12
ATC
[U] gabapentin; oral
1.4
8.8
376
2747
M01AH05
ATC
etoricoxib; oral
1.3
8.8
1478
13161
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.7
8.6
145
857
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
8.6
406
3018
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
8.6
809
6681
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.7
8.6
149
889
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
8.3
410
3071
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
8.5
8.3
17
20
SFA10
NOMESCO Finland
One-surface restoration
1.3
8.2
1251
10961
S29
ICPC
Skin symptom/complaint other
1.4
8.2
406
3042
R51.80
ICD-10 Finland
Headache
1.4
8.1
315
2259
VALMI, ,
NOMESCO Finland
1.4
8.1
505
3928
N40
ICD-10 Finland
Hyperplasia of prostate
1.3
8.1
527
4128
R02
ICPC
Shortness of breath/dyspnoea
1.5
8.0
280
1969
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.1
8.0
71
340
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.9
887
7479
J01FA06
ATC
roxithromycin; oral
1.3
7.9
894
7549
P01AB01
ATC
metronidazole; oral, rectal
1.3
7.8
872
7342
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
4.1
7.8
21
52
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
7.8
389
2918
M04AA01
ATC
allopurinol; systemic
1.4
7.8
298
2134
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
7.7
135
807
R42
ICD-10 Finland
Dizziness and giddiness
1.4
7.7
473
3665
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.6
7.7
158
986
WZA90
NOMESCO Finland
Other medical or dental certificate
1.3
7.7
496
3874
J01FF01
ATC
clindamycin; systemic
1.3
7.7
614
4948
WX704
NOMESCO Finland
Intubation
1.6
7.6
174
1117
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
4.2
7.5
19
45
J01DA01
ATC
[U] cefalexin
1.3
7.5
1426
12778
SPAT1301
SPAT
No procedures
1.3
7.4
662
5414
R01AD08
ATC
fluticasone; nasal
1.3
7.4
612
4954
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.8
7.4
113
652
XW1AT
NOMESCO Finland
Biopsy from other organ close to skin with ultrasound quidance
3.8
7.4
22
59
R22
ICD-10 Finland
Localized swelling, mass and lump of skin and subcutaneous tissue
2.3
7.3
55
246
A02BC02
ATC
pantoprazole; systemic
1.3
7.3
1617
14714
S10
ICPC
Boil/carbuncle
1.7
7.3
129
775
J01AA02
ATC
doxycycline; systemic
1.3
7.3
1877
17396
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
7.3
846
7149
TPH04
NOMESCO Finland
Cathetrisation of vein
1.3
7.2
486
3817
N03AX16
ATC
[U] pregabalin
1.3
7.2
519
4120
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.1
631
5148
SDA03
NOMESCO Finland
Periodontal treatment
1.3
7.1
870
7395
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
7.0
345
2579
WX402
NOMESCO Finland
General anaesthesia
1.3
6.9
462
3622
D01
ICPC
Abdominal pain/cramps general
1.5
6.9
226
1567
M25.5
ICD-10 Finland
Pain in joint
1.3
6.9
701
5815
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.6
6.9
148
934
L01
ICPC
Neck symptom/complaint
1.4
6.9
313
2309
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.5
6.8
235
1649
QAE15
NOMESCO Finland
Excision of other superficial lesion of skin from head and neck
9.3
6.8
13
14
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.5
6.7
217
1501
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.2
6.7
1171
10336
T82
ICPC
Obesity
1.9
6.7
82
442
A02BC05
ATC
esomeprazole; systemic
1.3
6.6
912
7838
R21
ICPC
Throat symptom/complaint
1.4
6.6
368
2806
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
2.0
6.6
67
338
R60.0
ICD-10 Finland
Localized oedema
1.4
6.5
252
1805
K03.82
ICD-10 Finland
Split tooth for reasons other than trauma
1.3
6.5
535
4315
D11.0
ICD-10 Finland
Benign neoplasm: Parotid gland
2.3
6.5
46
201
D22.3
ICD-10 Finland
Melanocytic naevi of other and unspecified parts of face
2.2
6.5
51
233
G44.2
ICD-10 Finland
Tension-type headache
1.4
6.5
269
1952
Z3226
NOMESCO Finland
Physiotherapist
1.3
6.5
387
2985
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
5.7
6.4
17
30
L72.0
ICD-10 Finland
Epidermal cyst
2.7
6.3
33
125
SPAT1325
SPAT
Vaccination
1.3
6.3
693
5798
ELB40
NOMESCO Finland
Partial parotidectomy
2.6
6.3
34
131
A06AC01
ATC
ispaghula (psylla seeds); oral
1.3
6.3
545
4426
Z01.2
ICD-10 Finland
Dental examination
1.2
6.3
971
8441
R06AX27
ATC
desloratadine; oral
1.3
6.2
564
4606
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.3
6.2
581
4763
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
5.7
6.1
16
28
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
5.7
6.1
16
28
C09CA01
ATC
losartan; oral
1.3
6.1
573
4699
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
6.1
279
2061
E88.2
ICD-10 Finland
Lipomatosis, not elsewhere classified
12.5
6.1
10
8
D07AC13
ATC
mometasone; topical
1.3
6.1
623
5167
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
2.6
6.1
32
122
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.3
6.0
375
2909

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
583
2848
2.35
65.02
1.3
1.3
—
—
—
0
0
1166
8796
1.59
28.43
2.2
2.1
—
—
—
0
0
2171
19771
1.58
16.75
4.9
4.6
1.90
2.14
mu/l
1.22
2018
18082
2532
24197
2.57
15.80
22.8
21.4
40.89
40.45
%
3.18
2332
22675
2336
21732
1.72
15.74
15.3
14.6
24.12
24.21
mg/l
0.04
1901
17246
2408
22606
1.85
15.60
17.6
16.7
139.93
139.71
mmol/l
4.53
2367
22058
2413
22674
1.85
15.49
17.8
16.9
3.98
3.98
mmol/l
0.36
2365
22101
2532
24214
2.55
15.46
22.8
21.3
250.86
247.56
e9/l
1.86
2476
23621
2533
24234
2.55
15.34
22.9
21.4
137.42
136.53
g/l
2.34
2506
23898
2532
24226
2.53
15.23
22.7
21.2
90.84
91.17
fl
3.43
2503
23891
2532
24227
2.53
15.21
22.7
21.2
30.28
30.39
pg
2.58
2503
23890
2532
24229
2.53
15.17
22.8
21.3
4.57
4.52
e12/l
5.24
2472
23562
2532
24230
2.52
15.15
22.8
21.3
6.73
6.74
e9/l
0.04
2472
23562
1812
16125
1.41
13.77
4.1
4.1
11.21
12.13
mm/h
2.21
1701
14938
2455
23323
1.89
13.33
18.4
16.9
79.06
79.24
umol/l
0.11
2455
23314
2451
23342
1.83
12.20
11.3
10.6
27.35
27.37
u/l
0.02
2377
22558
2201
20436
1.49
12.13
6.5
5.8
40.36
40.02
mmol/mol
0.95
2055
18975
1666
14780
1.35
11.82
4.6
4.2
—
—
—
0
0
2390
22656
1.65
11.40
14.6
13.7
—
—
—
0
0
2277
21363
1.52
11.18
5.0
4.6
6.04
5.99
mmol/l
1.03
2101
19508
2356
22274
1.60
11.14
5.3
5.0
2.75
2.75
mmol/l
0.03
2191
20589
1200
10269
1.31
10.31
2.5
2.6
—
—
—
0
0
1870
17032
1.35
10.22
7.8
7.7
77.59
78.08
u/l
0.16
1776
16112
1793
16272
1.33
9.77
4.0
3.8
14.87
14.80
pmol/l
0.59
1664
14774
2313
21889
1.50
9.65
4.8
4.5
4.62
4.64
mmol/l
0.43
2169
20344
2297
21741
1.47
9.23
4.7
4.5
1.41
1.44
mmol/l
2.76
2136
20095
1626
14621
1.30
9.12
3.1
3.2
54.07
52.02
u/l
0.28
1514
13625
1983
18360
1.33
8.75
20.2
18.6
332.86
332.78
g/l
0.16
1973
18234
1557
13968
1.28
8.65
4.5
4.3
1563.74
1834.33
e6/l
0.06
19
210
1248
10913
1.28
8.44
5.4
5.9
0.04
0.04
e9/l
0.01
1050
9476
747
6125
1.31
8.33
2.9
3.1
—
—
—
0
0
1271
11173
1.27
8.10
5.4
6.0
1.93
1.94
e9/l
0.05
1113
9911
1242
10890
1.27
8.08
5.4
5.9
0.58
0.59
e9/l
0.98
1048
9458
1451
12968
1.27
8.01
5.0
5.0
6.87
6.77
mmol/l
0.82
1354
12218
1716
15653
1.28
8.01
4.0
3.8
—
—
—
0
0
1279
11288
1.26
7.75
5.5
6.1
0.20
0.19
e9/l
0.67
1114
9923
982
8401
1.27
7.73
3.6
3.3
5.85
5.80
ph
0.19
63
597
2005
18696
1.31
7.70
18.1
17.3
15.40
14.98
%
1.94
1990
18352
1234
10877
1.26
7.44
6.5
7.1
1.21
1.21
mmol/l
0.79
1088
9254
1410
12642
1.25
7.23
8.8
9.2
4.13
4.15
e9/l
0.12
1214
11073
2220
21065
1.36
7.15
4.2
4.0
1.34
1.33
mmol/l
0.29
2053
19337
840
7106
1.27
7.12
4.0
3.9
7.10
8.77
mg/mmol
0.75
553
4543
1298
11545
1.25
7.10
6.2
6.4
11.68
11.59
umol/l
0.07
1242
10994
1184
10442
1.25
6.92
3.9
3.6
0.00
0.00
estimate
0.99
194
2073
591
4813
1.29
6.73
1.7
1.8
1.07
1.20
mg/l
0.58
454
3685
819
6947
1.26
6.70
2.3
2.5
—
—
—
0
0
1179
10423
1.24
6.65
5.2
4.8
0.00
0.00
estimate
0.50
185
1969
534
4302
1.30
6.58
3.8
3.7
307.51
442.71
ng/l
0.70
420
3419
335
2528
1.37
6.44
1.7
1.8
—
—
—
0
0
796
6761
1.26
6.37
3.5
3.3
334.85
308.08
mg/l
0.06
542
4370
1187
10536
1.23
6.34
3.9
3.6
0.00
0.00
estimate
1.08
175
1871
843
7234
1.24
6.11
3.3
3.3
33.35
36.81
u/l
0.63
797
6880
1120
9913
1.23
6.06
5.8
6.3
1.21
1.21
mmol/l
0.44
1035
9051
1117
9906
1.22
5.86
5.5
6.2
0.67
0.68
%
0.30
1031
9264
1010
8868
1.23
5.84
2.0
2.0
96.60
95.03
pmol/l
0.45
525
4738
1153
10264
1.22
5.82
5.7
6.5
8.49
8.71
%
1.57
1067
9626
878
7607
1.23
5.75
3.8
3.7
64.65
104.34
e6/l
1.65
627
5496
1146
10214
1.22
5.66
5.5
6.1
2.81
2.85
%
0.27
1061
9563
987
8686
1.22
5.49
2.3
2.2
75.44
77.05
nmol/l
1.11
887
7788
336
2607
1.33
5.37
1.4
1.5
—
—
—
0
0
1173
10514
1.21
5.37
5.5
6.2
27.26
27.70
%
0.69
1086
9886
1157
10377
1.21
5.21
5.4
6.0
57.90
57.33
%
0.90
1070
9751
665
5642
1.24
5.21
4.1
4.0
91.54
89.59
%
1.21
649
5514
999
8841
1.21
5.16
5.0
4.8
2.86
2.65
ug/l
0.19
908
7961
818
7101
1.22
5.13
3.5
3.2
7.86
7.75
mmol/l
0.27
707
6005
1148
10300
1.20
5.12
5.9
6.5
—
—
—
0
0
710
6085
1.23
5.03
3.9
4.5
—
—
—
0
0
84
502
1.70
4.94
6.2
7.8
105.62
105.43
mmol/l
0.12
77
444
84
502
1.70
4.94
6.2
7.8
11.13
11.36
mmol/l
0.25
77
444
775
6719
1.22
4.88
2.2
2.2
189.27
238.72
u/l
1.10
730
6309
198
1434
1.41
4.88
5.8
7.2
24.70
24.48
mmol/l
0.33
189
1364
215
1585
1.39
4.78
1.5
1.4
—
—
—
0
0
134
909
1.50
4.66
5.3
5.6
0.93
0.88
%
0.73
125
849
135
919
1.49
4.62
5.3
5.6
1.59
1.64
%
0.23
126
857
698
6018
1.22
4.61
3.0
2.7
1434.60
4956.35
umol/l
3.65
623
5290
281
2179
1.32
4.52
1.3
1.5
—
—
—
0
0
1149
10394
1.19
4.48
17.2
15.2
1.28
1.28
inr
0.01
286
2987
577
4894
1.23
4.45
3.8
3.5
—
—
—
0
0
452
3733
1.26
4.45
3.0
2.8
1.26
1.04
e6/l
0.60
274
2143
311
2453
1.30
4.43
2.5
2.3
144.15
148.21
ug/g
0.07
252
1964
793
6951
1.20
4.37
2.7
2.6
60.64
70.60
u/l
0.37
733
6445
109
718
1.54
4.36
5.6
6.6
1.18
1.35
mmol/l
1.76
99
624
159
1138
1.42
4.22
2.5
2.4
—
—
—
0
0
755
6633
1.19
4.00
3.5
3.3
58.25
74.67
e6/l
0.43
587
5141
85
544
1.58
3.89
4.9
4.4
—
—
—
0
0
239
1853
1.32
3.87
2.7
2.9
189.53
190.26
ng/l
0.01
218
1685
732
6432
1.19
3.85
4.0
4.2
7.39
7.40
ph
1.28
107
1257
236
1832
1.32
3.79
3.8
3.3
—
—
—
0
0
691
6050
1.19
3.77
3.5
3.2
0.44
0.43
e6/l
0.02
528
4625
170
1258
1.38
3.75
7.9
10.9
—
—
—
0
0
537
4598
1.21
3.72
2.6
2.6
4.53
5.02
e6/l
0.49
482
4150
1042
9477
1.17
3.55
5.3
5.0
35.67
35.49
g/l
0.48
975
8856
433
3650
1.22
3.50
1.3
1.3
20.41
35.16
iu/ml
5.02
134
1183
533
4587
1.20
3.49
4.6
3.9
1.02
1.02
kg/l
0.55
72
653
198
1520
1.33
3.46
4.2
5.0
—
—
—
0
0
274
2203
1.27
3.39
7.2
8.7
125.18
122.47
g/l
1.34
266
2144
515
4431
1.20
3.38
1.3
1.2
2.55
1.63
u/ml
0.46
142
1173
320
2622
1.25
3.37
6.6
7.9
1.30
1.02
mmol/l
0.75
260
2083
291
2368
1.26
3.26
6.8
8.3
94.91
95.66
%
0.78
278
2283
41
231
1.79
3.08
1.4
1.4
24.81
29.03
u/l
0.35
33
186
26
125
2.09
3.08
1.5
1.3
1.39
1.15
nmol/l
0.52
20
98
143
1066
1.36
3.06
4.2
3.5
—
—
—
0
0
459
3942
1.20
3.06
1.7
1.7
1087.35
1174.63
nmol/l
1.40
371
3002
410
3494
1.21
2.97
3.2
3.0
2.91
1.97
e6/l
1.03
233
1909
410
3495
1.21
2.96
1.4
1.2
5.25
11.76
u/ml
2.69
158
1371
315
2627
1.23
2.84
6.7
7.9
5.19
5.10
kpa
0.85
303
2512
964
8826
1.15
2.84
2.7
2.8
124.79
145.73
ug/l
1.87
902
8162
315
2628
1.23
2.83
6.7
7.9
12.17
12.13
kpa
0.04
302
2515
152
1165
1.32
2.74
1.2
1.2
—
—
—
0
0
38
220
1.74
2.65
1.2
1.4
197295.61
61890.44
e6/l
0.57
28
157
499
4374
1.17
2.62
3.4
2.9
547.42
549.20
mosm/kgh2o
0.06
428
3773
599
5365
1.15
2.36
2.2
2.4
—
—
—
0
0
236
1950
1.23
2.35
1.4
1.4
—
—
—
0
0
653
5887
1.15
2.34
3.3
3.1
—
—
—
0
0
124
948
1.32
2.32
1.6
1.9
—
—
—
0
0
46
293
1.58
2.28
1.3
1.3
0.54
0.64
nmol/l
1.62
46
279
368
3203
1.17
2.12
2.0
2.1
—
—
—
0
0
119
918
1.31
2.11
1.1
1.1
151.00
181.53
titre
—
5
17
289
2470
1.19
2.06
1.3
1.3
—
—
—
0
0
791
7288
1.12
1.98
3.8
3.4
2.35
2.35
mmol/l
0.65
693
6454
695
6362
1.13
1.94
3.0
3.0
1253.30
1325.39
ng/l
0.21
607
5431
570
5155
1.14
1.93
3.0
3.0
0.75
0.73
ug/l
0.19
394
3373
42
274
1.54
1.92
1.3
1.3
—
—
—
0
0
171
1399
1.24
1.92
1.3
1.2
—
—
—
0
0
16
78
2.06
1.90
1.0
1.0
—
0.29
—
0
20
151
1221
1.25
1.88
3.2
3.4
4.57
4.48
pmol/l
0.52
133
1078
39
252
1.56
1.87
1.3
1.3
—
—
nmol/l
—
0
0
354
3105
1.16
1.86
1.3
1.2
—
—
—
0
0
5
12
4.17
1.82
1.0
1.1
—
—
—
0
0
711
6547
1.12
1.78
4.3
3.9
—
—
—
0
0
155
1270
1.23
1.74
1.2
1.2
165.35
158.75
iu/ml
0.05
61
458
442
3962
1.14
1.72
3.4
3.1
2.44
2.45
mmol/l
1.30
382
3495
22
125
1.77
1.72
1.6
2.9
7.39
7.42
ph
—
8
40
389
3460
1.15
1.70
2.4
2.1
30.53
29.93
s
1.13
375
3359
185
1549
1.21
1.69
1.2
1.2
—
—
—
0
0
152
1839
0.82
1.67
4.0
3.9
—
—
—
0
0
95
740
1.29
1.64
1.3
1.4
33.77
30.55
iu/l
0.39
86
625
126
1019
1.25
1.61
1.7
1.7
—
—
—
0
0
601
5516
1.12
1.59
6.5
6.8
—
—
—
0
0
100
788
1.28
1.58
2.6
2.3
560.21
511.09
ug/l
0.08
94
745
286
2503
1.16
1.57
2.8
2.8
9.02
8.24
umol/l
0.20
250
2209
550
5026
1.12
1.57
1.6
1.5
20.11
20.29
nmol/l
0.11
476
4307
12
57
2.11
1.55
1.2
1.1
254.71
284.54
pmol/l
—
7
41
23
138
1.67
1.51
2.2
2.8
35.66
41.21
%
0.67
16
72
199
1698
1.19
1.50
1.3
1.3
—
—
—
0
0
11
51
2.16
1.50
1.3
1.3
62.86
66.00
ug/l
—
5
23
57
418
1.37
1.49
1.7
1.3
—
—
—
0
0
101
804
1.27
1.49
3.8
3.5
279.99
2781.37
u/ml
1.01
90
695
612
5652
1.11
1.44
3.6
3.3
—
—
—
0
0
37
253
1.47
1.43
1.4
1.4
288.71
317.40
pmol/l
0.21
31
221
237
2062
1.16
1.43
3.7
3.7
5.84
5.84
kpa
0.02
228
2003
261
2288
1.16
1.42
3.8
4.2
11.15
20.16
ug/l
0.90
209
1871
64
483
1.33
1.41
2.2
2.3
126.77
129.82
g/l
0.40
43
351
11
53
2.08
1.38
1.2
1.2
66.57
65.20
mu/l
—
6
41
188
1611
1.18
1.37
4.2
4.0
85.05
92.90
ng/l
0.70
160
1418
163
1380
1.19
1.37
2.7
3.1
132.46
129.27
g/l
1.00
155
1345
15
82
1.83
1.35
1.0
1.1
—
—
—
0
0
612
5672
1.10
1.34
4.4
3.9
0.00
0.00
estimate
1.08
179
1878
0
39
0.00
1.33
0.0
2.0
—
18.13
—
0
39
235
2056
1.16
1.33
3.7
3.7
1.97
1.95
mmol/l
0.03
194
1724
195
1683
1.17
1.32
2.8
2.9
4.63
4.60
kpa
0.06
190
1628
81
640
1.27
1.30
1.4
1.5
306.23
277.04
ug/g
0.46
39
383
38
267
1.43
1.30
1.9
2.6
—
—
—
0
0
227
1987
1.16
1.28
2.7
2.2
347.73
370.16
nmol/l
1.10
211
1831
234
2054
1.15
1.27
3.0
2.4
32.82
60.99
u/l
0.66
198
1783
50
371
1.35
1.26
1.3
1.5
—
—
—
0
0
111
1338
0.82
1.24
1.9
1.9
1.24
1.39
g/l
0.42
104
1228
36
503
0.71
1.23
5.1
4.8
2.58
2.51
mmol/l
0.06
29
345
639
5962
1.10
1.22
1.8
1.7
1.40
1.39
mmol/l
0.07
574
4999
28
188
1.49
1.21
1.1
1.0
0.38
0.39
u/ml
—
7
60
91
739
1.24
1.19
1.6
1.6
—
—
—
0
0
322
2903
1.12
1.18
1.3
1.3
537.78
515.71
titre
0.08
72
606
174
1507
1.17
1.15
2.3
3.2
4.21
5.61
e9/l
1.73
138
1231
18
110
1.64
1.15
1.3
1.2
—
—
—
0
0
893
8476
1.08
1.13
3.7
3.6
45.02
48.23
ng/l
0.08
607
5956
70
558
1.26
1.09
1.5
1.7
31492.21
14276.02
e6/l
0.48
56
401
68
541
1.26
1.08
1.4
1.4
8.97
9.09
u/l
0.03
59
441
107
896
1.20
1.06
2.6
2.6
—
—
—
0
0
147
1700
0.86
1.06
2.4
2.8
10.59
10.57
g/l
0.02
140
1558
36
262
1.38
1.05
3.3
3.2
2.45
25.35
nmol/l
0.56
36
255
224
1991
1.14
1.05
6.3
7.6
1.46
1.40
mmol/l
0.35
219
1947
15
90
1.67
1.04
1.1
1.6
—
—
—
0
0
34
246
1.39
1.03
3.3
6.8
7.25
7.51
mmol/l
0.20
29
207
22
146
1.51
1.03
1.3
1.3
1.52
1.55
g/l
0.22
22
146
84
690
1.22
1.02
1.0
1.1
—
—
—
0
0
575
5384
1.09
1.01
2.2
2.2
2.84
2.98
mg/l
0.83
487
4587
256
2303
1.12
1.00
1.5
1.6
—
—
—
0
0
400
3687
1.10
1.00
3.1
3.4
0.82
0.82
mmol/l
0.39
383
3483
9
49
1.84
0.98
1.3
1.3
34.33
25.08
%
—
9
37
5
23
2.18
0.98
1.8
3.2
—
—
—
0
0
23
157
1.47
0.96
1.3
1.2
—
—
—
0
0
37
276
1.35
0.95
1.5
1.5
—
—
—
0
0
87
1041
0.83
0.95
1.7
1.8
1.59
1.53
g/l
0.23
74
905
0
32
0.00
0.95
0.0
1.1
—
71.46
—
0
27
72
588
1.23
0.94
2.1
2.3
89.46
122.31
ug/min
0.34
42
367
8
143
0.56
0.93
1.0
1.6
—
—
—
0
0
21
304
0.69
0.93
1.2
1.2
—
—
—
0
0
999
9585
1.07
0.91
8.8
9.7
0.00
0.00
e9/l
1.15
798
7867
69
563
1.23
0.91
2.1
1.9
207.09
207.78
pmol/l
0.02
64
532
22
151
1.46
0.90
1.5
2.0
6.25
7.09
mmol/l
1.52
17
95
218
1962
1.12
0.87
1.4
1.4
—
—
—
0
0
107
916
1.18
0.87
1.1
1.1
—
—
—
0
0
42
325
1.30
0.86
1.0
1.1
1.80
1.82
u/ml
0.01
17
167
23
161
1.43
0.86
1.2
1.0
—
—
—
0
0
26
187
1.39
0.85
1.6
1.8
—
—
—
0
0
6
31
1.94
0.84
1.3
1.5
56.48
137.71
ng/l
—
6
31
60
488
1.23
0.83
2.7
1.7
0.79
0.84
nmol/l
0.28
48
412
22
154
1.43
0.83
1.1
1.1
—
—
—
0
0
38
292
1.31
0.83
1.1
1.1
2.26
4.97
u/ml
1.18
16
138
15
225
0.66
0.81
1.3
1.6
—
—
—
0
0
28
206
1.36
0.81
1.3
1.5
32.71
30.63
%
0.12
17
132
494
4644
1.08
0.80
1.7
1.7
27804181.70
33738793.44
pmol/l
0.08
428
3868
554
5861
0.93
0.80
1.4
1.4
—
—
—
0
0
37
285
1.30
0.80
2.1
1.8
14.46
23.87
ug/l
1.41
37
280
0
24
0.00
0.79
0.0
1.0
—
—
—
0
0
16
106
1.51
0.78
1.4
1.4
—
—
—
0
0
251
2293
1.10
0.78
1.5
1.6
—
—
—
0
0
216
1958
1.11
0.78
2.4
2.3
9.42
7.68
ug/l
0.38
196
1752
15
98
1.53
0.78
1.1
1.1
109.09
195.31
iu/ml
1.23
15
98
7
122
0.57
0.78
1.0
1.3
—
—
—
0
0
14
210
0.66
0.77
1.6
1.4
—
—
—
0
0
17
245
0.69
0.76
2.2
2.2
—
—
—
0
0
60
494
1.22
0.76
1.7
1.4
199.00
854.87
e6/l
1.20
52
400
60
494
1.22
0.76
1.6
1.4
17.26
27.08
e6/l
0.26
47
384
146
1295
1.13
0.76
1.3
1.3
268.82
213.57
u/ml
0.34
138
1191
153
1362
1.13
0.76
2.6
2.8
—
—
—
0
0
11
67
1.64
0.75
1.0
1.3
—
—
—
0
0
5
24
2.09
0.74
1.0
1.0
—
—
—
0
0
17
243
0.70
0.74
1.1
1.2
—
—
—
0
0
206
1875
1.11
0.71
8.3
9.0
—
—
—
0
0
59
490
1.21
0.70
1.5
1.9
4.30
4.75
iu/l
0.15
20
165
5
26
1.92
0.70
2.2
2.8
0.40
0.42
u/field
—
5
26
30
388
0.77
0.70
1.1
1.4
65.21
60.81
mmol/l
0.21
24
313
340
3170
1.08
0.70
1.6
1.7
—
—
—
0
0
25
186
1.35
0.70
4.9
4.9
581.76
48.96
u/ml
—
7
52
20
145
1.38
0.65
3.9
2.4
—
—
—
0
0
47
385
1.22
0.65
3.4
3.6
—
—
—
0
0
422
3981
1.07
0.64
1.4
1.5
2.40
2.52
g/l
0.64
246
2492
77
662
1.17
0.64
1.2
1.1
—
—
—
0
0
71
609
1.17
0.62
1.1
1.2
—
—
—
0
0
27
208
1.30
0.62
1.1
1.1
6.71
2.68
u/ml
0.48
12
75
90
788
1.15
0.60
1.2
1.2
0.37
0.81
u/ml
—
7
68
9
138
0.65
0.60
19.6
14.3
979.78
814.22
nmol/l
—
9
133
0
20
0.00
0.60
0.0
1.3
—
—
—
0
0
222
2049
1.09
0.60
7.3
7.9
10.03
9.89
mmol/l
0.11
211
1953
35
281
1.25
0.59
1.1
1.1
0.33
1.43
u/ml
1.51
11
113
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
0
22
0.00
0.59
0.0
1.2
—
—
—
0
0
34
420
0.81
0.58
1.4
1.3
—
—
—
0
0
17
123
1.38
0.57
1.3
1.0
—
—
—
0
0
17
230
0.74
0.57
1.2
1.2
—
—
—
0
0
18
241
0.75
0.56
2.1
2.4
—
—
—
0
0
163
1489
1.10
0.56
2.4
2.4
12.08
22.11
au/ml
—
10
111
40
483
0.83
0.55
1.5
1.7
—
—
—
0
0
13
90
1.45
0.55
1.1
1.1
1258.00
1523.14
miu/ml
0.50
13
90
103
918
1.13
0.55
3.2
4.7
—
—
—
0
0
8
123
0.65
0.54
1.8
1.6
4.38
3.84
u/field
—
8
93
119
1071
1.12
0.54
2.6
3.4
25.31
25.29
mmol/l
0.03
114
1039
6
38
1.58
0.54
1.0
1.1
—
—
—
0
0
280
2623
1.08
0.54
1.5
1.6
—
—
—
0
0
162
1485
1.10
0.52
8.0
9.7
0.68
0.67
%
0.16
162
1473
19
249
0.76
0.52
2.4
2.5
—
—
—
0
0
209
1939
1.08
0.52
2.3
2.2
12.96
13.22
nmol/l
0.18
188
1733
6
40
1.50
0.51
4.8
7.5
—
—
—
0
0
50
425
1.18
0.51
1.2
1.2
41.73
43.45
u/ml
—
8
41
13
180
0.72
0.51
1.7
1.4
—
—
—
0
0
116
1281
0.90
0.50
1.4
1.6
—
—
—
0
0
13
179
0.72
0.50
1.6
1.4
—
—
—
0
0
33
270
1.23
0.50
1.3
1.6
63.87
61.12
%
0.13
15
173
14
101
1.39
0.49
3.4
13.8
—
—
—
0
0
314
2968
1.07
0.48
5.6
6.2
1.03
1.03
mmol/l
0.03
294
2768
80
709
1.13
0.48
3.1
4.1
3.87
3.91
mmol/l
0.52
80
702
57
493
1.16
0.48
3.1
2.7
—
—
—
0
0
144
1569
0.91
0.48
2.5
2.5
—
—
—
0
0
7
48
1.46
0.46
1.4
1.3
—
—
—
0
0
147
1352
1.09
0.46
1.3
1.3
72.79
60.69
au/ml
—
7
82
160
1478
1.09
0.46
1.4
1.4
—
—
—
0
0
18
232
0.77
0.46
1.1
1.2
—
—
—
0
0
17
129
1.32
0.45
5.8
6.4
—
—
—
0
0
28
228
1.23
0.45
1.1
1.0
2.24
1.94
u/ml
0.09
13
103
60
684
0.87
0.45
3.2
2.3
39.11
37.81
g/l
1.10
51
609
24
192
1.25
0.45
2.5
2.3
716.53
644.41
ml
0.52
17
124
41
481
0.85
0.44
3.1
2.6
15.53
16.21
%
0.49
26
246
160
1482
1.08
0.44
8.1
9.8
92.59
93.94
%
1.17
160
1474
27
329
0.82
0.44
1.3
1.2
—
—
—
0
0
154
1425
1.09
0.43
3.6
3.6
7.43
7.41
ph
1.08
19
184
14
185
0.76
0.43
1.6
1.4
—
—
—
0
0
66
584
1.13
0.42
2.4
2.0
—
—
—
0
0
5
33
1.52
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
8
59
1.36
0.41
1.3
1.0
—
—
—
0
0
8
59
1.36
0.41
2.8
1.5
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
1.73
—
0
10
67
597
1.13
0.40
2.4
2.1
—
—
—
0
0
32
269
1.19
0.39
2.8
2.9
—
—
—
0
0
292
2777
1.06
0.39
4.8
4.5
30.83
31.93
%
1.08
194
1903
155
1443
1.08
0.39
3.6
3.6
5.18
5.16
kpa
0.10
145
1382
61
542
1.13
0.38
2.0
2.4
—
—
—
0
0
17
214
0.79
0.38
1.0
1.2
—
—
—
0
0
73
657
1.11
0.37
2.9
3.3
—
—
—
0
0
44
383
1.15
0.37
1.5
1.2
—
—
—
0
0
8
114
0.70
0.37
1.6
1.8
—
—
—
0
0
57
506
1.13
0.37
2.4
3.0
30.98
37.23
umol/l
1.54
52
459
9
70
1.29
0.36
1.6
1.3
70.56
137.63
nmol/l
—
9
55
62
554
1.12
0.36
2.5
2.2
—
—
—
0
0
5
77
0.65
0.35
1.2
1.2
—
—
—
0
0
54
607
0.89
0.35
1.2
1.2
60.00
101.48
titre
—
6
54
51
451
1.13
0.35
1.5
1.3
—
—
—
0
0
14
108
1.30
0.35
1.0
2.4
695.43
1203.22
u/ml
0.87
14
108
28
236
1.19
0.35
1.8
1.4
—
—
—
0
0
202
2135
0.94
0.34
2.1
2.2
0.21
0.21
g/l
0.17
190
2000
10
73
1.37
0.34
1.0
1.0
—
—
—
0
0
66
595
1.11
0.34
2.4
2.1
—
—
—
0
0
91
835
1.09
0.33
1.9
2.0
22.19
21.61
s
0.23
83
739
13
100
1.30
0.33
1.3
2.2
—
—
—
0
0
103
951
1.09
0.33
1.2
1.2
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
65
591
1.10
0.30
2.4
2.2
—
—
—
0
0
65
591
1.10
0.30
1.2
1.2
58.00
35.54
u/ml
—
6
27
79
726
1.09
0.29
12.3
9.6
—
—
—
0
0
19
228
0.83
0.29
1.5
1.4
10314.42
103552.68
e6/l
1.81
12
134
16
195
0.82
0.28
1.4
1.3
—
—
—
0
0
10
76
1.32
0.28
4.9
7.5
23.87
24.90
mmol/l
—
10
70
72
782
0.92
0.27
3.8
3.2
0.21
0.26
g/l
0.67
33
327
8
64
1.25
0.27
1.3
1.5
88.37
180.86
nmol/24h
—
8
64
17
204
0.83
0.27
1.2
1.5
168.71
213.17
pmol/l
0.42
17
204
329
3178
1.04
0.26
2.4
2.6
2.37
2.30
g/l
1.78
318
2965
8
66
1.21
0.26
1.0
1.1
—
—
—
0
0
32
363
0.88
0.26
1.0
1.1
—
—
—
0
0
59
539
1.10
0.26
1.2
1.2
—
—
—
0
0
10
77
1.30
0.26
1.6
2.4
—
—
—
0
0
30
263
1.14
0.25
1.1
1.0
0.93
2.02
u/ml
0.84
14
128
22
188
1.17
0.25
1.7
1.5
—
—
—
0
0
15
123
1.22
0.25
1.1
1.4
—
—
—
0
0
41
456
0.90
0.25
1.1
1.4
—
—
—
0
0
17
202
0.84
0.24
1.1
1.2
—
—
—
0
0
172
1802
0.95
0.24
3.8
4.2
1.23
1.23
mmol/l
0.64
156
1572
11
137
0.80
0.24
1.2
1.1
—
—
—
0
0
6
81
0.74
0.24
1.0
1.1
—
—
—
0
0
6
82
0.73
0.24
1.0
1.0
—
—
—
0
0
47
427
1.10
0.23
2.6
2.9
—
—
—
0
0
43
389
1.11
0.23
1.1
1.2
16.36
38.66
u/l
2.53
35
336
20
171
1.17
0.23
1.3
1.2
2.59
2.03
mmol/l
0.95
20
163
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
18
211
0.85
0.23
1.0
1.2
—
—
—
0
0
29
327
0.89
0.23
2.8
2.7
—
—
—
0
0
45
409
1.10
0.23
4.0
3.1
0.86
0.83
nmol/l
0.20
39
317
65
700
0.93
0.22
4.4
3.8
1.30
1.74
ratio
—
5
56
5
41
1.22
0.22
1.0
1.1
—
—
—
0
0
41
372
1.10
0.21
1.3
1.4
—
—
—
0
0
67
720
0.93
0.21
4.4
3.8
121.35
71.07
mg/l
0.28
53
577
52
565
0.92
0.21
1.7
1.6
—
—
—
0
0
28
248
1.13
0.21
1.1
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
6.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
12.31
—
0
11
99
935
1.06
0.21
1.9
2.0
3.67
2.06
ug/l
0.42
87
837
179
1719
1.04
0.21
3.8
4.1
0.63
0.70
%
0.15
64
585
34
306
1.11
0.21
1.4
2.2
—
3.50
—
0
6
76
811
0.94
0.21
3.1
2.5
9.35
10.25
g/l
1.71
67
735
179
1863
0.96
0.20
2.6
2.7
66.29
66.64
g/l
0.29
164
1716
45
491
0.92
0.20
3.7
4.0
—
—
—
0
0
50
460
1.09
0.20
2.3
2.2
—
—
—
0
0
26
230
1.13
0.20
1.9
1.5
—
—
—
0
0
196
1887
1.04
0.20
3.8
4.2
0.93
0.92
%
0.02
71
687
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
110
1045
1.05
0.20
3.8
3.7
—
—
—
0
0
230
2226
1.04
0.19
4.1
4.3
—
—
—
0
0
308
2999
1.03
0.18
2.5
2.6
21.99
23.19
%
0.90
260
2578
17
147
1.16
0.18
1.2
1.1
—
—
—
0
0
51
474
1.08
0.17
2.9
3.6
33.02
27.01
mg/l
0.32
28
295
24
214
1.12
0.17
3.3
3.0
63.44
39.99
mg/l
0.31
18
162
29
320
0.91
0.17
1.1
1.1
—
—
—
0
0
57
533
1.07
0.17
1.4
1.2
171.28
207.49
miu/ml
0.27
23
224
25
278
0.90
0.17
1.0
1.0
2.33
2.08
u/ml
—
7
118
43
398
1.08
0.16
1.7
1.9
5.62
5.18
mmol/24h
0.25
38
351
14
162
0.86
0.16
2.1
1.4
75.71
84.96
umol/l
1.03
14
162
16
183
0.87
0.16
1.3
1.1
—
60.60
—
0
8
11
92
1.20
0.16
2.5
2.6
—
—
—
0
0
351
3434
1.03
0.16
2.5
2.6
12.79
13.19
umol/l
0.56
334
3221
37
341
1.09
0.15
1.3
1.2
4.15
5.07
u/ml
0.15
20
146
13
111
1.17
0.15
1.5
2.5
—
—
—
0
0
26
235
1.11
0.15
1.2
1.5
0.24
0.29
nmol/l
0.44
21
180
6
79
0.76
0.15
2.5
2.2
0.62
1.17
ug/l
—
6
70
10
83
1.21
0.15
1.9
1.5
—
—
—
0
0
9
79
1.14
0.15
4.9
5.1
—
—
—
0
0
68
718
0.95
0.15
4.4
3.8
40.76
63.50
mg/l
1.27
52
575
14
161
0.87
0.15
1.0
1.0
—
—
—
0
0
39
362
1.08
0.14
2.9
2.7
—
—
—
0
0
8
97
0.82
0.13
1.3
1.2
—
0.10
g/l
—
0
9
19
170
1.12
0.13
1.1
1.0
295.54
307.50
ng/l
0.10
13
110
19
170
1.12
0.13
1.0
1.0
807.60
714.73
ng/l
—
10
108
30
325
0.92
0.13
2.0
2.5
3.83
216.38
u/ml
0.97
30
317
38
407
0.93
0.13
1.4
1.6
—
—
—
0
0
9
106
0.85
0.13
2.9
2.6
—
—
—
0
0
38
406
0.94
0.12
1.2
1.4
93.23
116.99
u/ml
—
6
77
39
416
0.94
0.12
1.1
1.2
361.23
276.95
u/ml
0.61
26
250
123
1270
0.97
0.12
1.5
1.5
—
—
—
0
0
16
143
1.12
0.11
1.6
1.9
11.84
5.34
umol/l
0.42
16
90
10
115
0.87
0.10
10.3
11.1
0.56
0.63
mmol/l
—
10
107
25
270
0.93
0.10
1.2
1.2
—
—
—
0
0
22
239
0.92
0.10
1.5
1.3
285.73
278.87
mosm/kgh2o
1.26
22
180
39
368
1.06
0.10
1.2
1.1
5.04
1509.57
iu/ml
—
8
86
11
96
1.15
0.10
1.5
1.2
—
—
—
0
0
30
320
0.94
0.09
1.1
1.1
—
—
—
0
0
35
330
1.06
0.09
1.4
1.7
0.65
0.83
g/l
0.67
24
251
47
448
1.05
0.09
3.9
4.0
59.57
57.69
%
0.53
47
448
17
155
1.10
0.09
1.5
1.5
—
—
—
0
0
39
370
1.05
0.09
1.3
1.3
—
—
—
0
0
6
54
1.11
0.09
4.8
7.3
—
—
—
0
0
24
257
0.93
0.08
4.1
2.3
1.37
1.42
g/24h
—
9
129
172
1686
1.02
0.08
4.0
4.3
0.00
0.44
%
1.14
48
482
5
63
0.79
0.08
1.0
1.6
—
—
—
0
0
16
146
1.10
0.08
1.4
1.5
12.75
13.38
u/l
0.16
16
139
5
64
0.78
0.08
1.6
1.1
—
—
—
0
0
38
362
1.05
0.07
1.0
1.1
—
—
—
0
0
6
71
0.84
0.07
1.3
2.2
—
—
—
0
0
6
72
0.83
0.07
1.2
1.4
19.00
26.83
%
—
6
66
23
215
1.07
0.07
1.4
1.5
—
—
—
0
0
6
75
0.80
0.07
1.8
1.8
—
—
—
0
0
188
1912
0.98
0.07
1.9
2.7
69.48
71.08
e9/l
0.26
149
1458
57
550
1.04
0.07
1.2
1.2
2.10
3.21
u/ml
—
6
53
26
275
0.94
0.06
1.1
1.3
—
—
—
0
0
8
94
0.85
0.06
2.0
3.0
—
—
—
0
0
19
203
0.94
0.06
1.6
1.5
—
—
—
0
0
12
131
0.92
0.05
3.2
3.7
—
—
—
0
0
10
90
1.11
0.05
1.1
1.9
2516.87
109.35
ug/l
—
10
77
42
406
1.04
0.05
1.3
1.6
—
—
—
0
0
12
130
0.92
0.04
1.3
1.0
—
—
—
0
0
19
201
0.94
0.04
1.5
1.4
0.55
0.35
g/l
—
10
138
19
201
0.94
0.04
1.5
1.4
3.23
2.95
g/l
—
9
138
19
201
0.94
0.04
1.5
1.4
6.02
6.81
g/l
—
10
139
32
332
0.96
0.04
2.2
2.2
—
—
—
0
0
181
1790
1.01
0.04
4.0
4.3
0.16
0.12
%
0.24
56
589
23
220
1.05
0.03
3.0
3.3
—
—
—
0
0
792
7894
1.00
0.03
3.0
2.9
—
—
—
0
0
13
122
1.07
0.02
1.3
2.4
—
—
—
0
0
11
103
1.07
0.02
1.1
1.1
—
—
—
0
0
16
167
0.96
0.01
1.6
1.3
1.52
1.00
u/ml
—
9
93
20
193
1.04
0.01
1.5
2.2
43.55
37.75
%
0.81
20
193
26
253
1.03
0.01
3.2
4.3
—
—
—
0
0
54
547
0.99
0.01
4.2
3.9
—
—
—
0
0
255
2542
1.00
0.01
1.8
2.6
1.72
1.81
%
0.82
226
2272
11
104
1.06
0.01
1.3
1.2
—
—
—
0
0
13
124
1.05
0.00
1.2
1.4
—
—
—
0
0
55
544
1.01
0.00
1.1
1.2
—
—
—
0
0
60
606
0.99
0.00
1.1
1.2
—
—
—
0
0
10
95
1.05
0.00
1.2
1.3
136.40
173.66
mmol/24h
—
10
95
38
385
0.99
0.00
5.0
3.3
—
—
—
0
0
23
231
1.00
0.00
1.2
1.1
—
—
—
0
0
12
124
0.97
0.00
1.5
1.5
—
—
—
0
0
38
377
1.01
0.00
2.4
3.7
1.47
1.46
%
0.01
33
340
40
403
0.99
0.00
1.7
2.2
185.09
2960.11
u/l
2.95
15
152
12
123
0.98
0.00
1.1
1.3
150.17
141.09
nmol/l
0.22
12
123
16
163
0.98
0.00
1.7
2.3
624.06
678.77
e6/l
0.24
16
157
20
197
1.02
0.00
2.4
1.9
11.57
11.33
%
0.08
20
197
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
174.40
—
0
5
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
46.06
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
1140.17
—
0
6
5
49
1.02
-0.00
1.2
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
60
1.00
-0.00
1.5
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
73
0.96
-0.00
2.1
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
27
270
1.00
-0.00
1.1
2.0
—
1040.00
—
0
12
7
71
0.99
-0.00
1.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
569.74
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_LIPO_SKIN_HEADFACENECK and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIPO_SKIN_HEADFACENECK 0.978 [0.87, 1.09] 0.695
Birth year 0.993 [0.99, 1.0] 0.116

During the follow-up period (1.1.1998 — 31.12.2019), 693 out of 6575 females with CD2_BENIGN_LIPO_SKIN_HEADFACENECK died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIPO_SKIN_HEADFACENECK 1.012 [0.91, 1.13] 0.832
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1221 out of 8836 males with CD2_BENIGN_LIPO_SKIN_HEADFACENECK died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIPO_SKIN_HEADFACENECK.

N-year risk Females Males
1 0.086% 0.145%
5 0.476% 1.003%
10 1.341% 2.612%
15 2.47% 4.84%
20 4.234% 8.152%

Relationships between endpoints

Index endpoint: CD2_BENIGN_LIPO_SKIN_HEADFACENECK – Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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