Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

CD2_BENIGN_LIPO_SKIN_HEADFACENECK

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D17.0&
  • Cause of death: ICD-10 D17.0&

2 out of 7 registries used, show all original rules.

2478

4. Check minimum number of events

None

2478

5. Include endpoints

None

2478

6. Filter based on genotype QC (FinnGen only)

2478

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D17
Name in latin
Neoplasma benignum lipomatosum cutis capitis/colli/nuchae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17408 7349 9961
Only index persons 16692 7138 9554
Unadjusted period prevalence (%)
Whole population 0.25 0.21 0.28
Only index persons 0.32 0.26 0.36
Median age at first event (years)
Whole population 53.92 54.12 53.85
Only index persons 53.72 53.94 53.56

-FinnGen-

Key figures

All Female Male
Number of individuals 2478 1152 1326
Unadjusted period prevalence (%) 0.50 0.39 0.58
Median age at first event (years) 56.57 54.57 58.32

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2224
Matched controls
22238
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D17.0
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
+∞
323.0
2224
25
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
14.5
323.0
875
953
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
7.1
170.0
457
780
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
11.2
150.6
299
304
QAE99
NOMESCO Finland
Other excision or repair surgery of skin and subcutaneous tissue in head and neck
12.0
105.1
199
180
R22.1
ICD-10 Finland
Localized swelling, mass and lump, neck
7.2
83.3
213
322
D17.9
ICD-10 Finland
Benign lipomatous neoplasm, unspecified
11.8
71.3
135
121
D17.2
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
7.0
46.0
117
174
NAR20
NOMESCO Finland
Complete excision of soft tissue tumour of spine, unspecified
87.0
46.0
51
6
QBE99
NOMESCO Finland
Other excision or repair of lesion of skin of trunk
6.9
45.8
118
179
D17
ICD-10 Finland
Benign lipomatous neoplasm
9.7
44.5
92
98
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
10.1
39.6
80
82
L72.1
ICD-10 Finland
Trichilemmal cyst
3.1
34.4
199
673
QCE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in upper limb
4.9
31.4
105
221
WX110
NOMESCO Finland
Local anesthesy
1.7
29.8
1479
11989
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.9
24.7
160
583
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.7
24.3
181
718
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
3.7
23.3
106
300
S18
ICPC
Laceration/cut
1.6
22.3
908
6759
SPAT1153
SPAT
Removal of sutures
1.6
21.4
698
4902
EP1BG
NOMESCO Finland
MRI examination of soft tissue of neck with high intesity magnet
11.4
20.0
37
33
D48.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Connective and other soft tissue
4.5
19.9
71
161
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.7
19.8
88
245
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
5.7
19.7
57
103
S78
ICPC
Lipoma
8.5
19.4
42
50
S04
ICPC
Lump/swelling localized
2.2
18.8
208
1008
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
18.7
964
7488
D21.0
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue of head, face and neck
13.1
17.9
31
24
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
16.8
133
549
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
16.3
1913
17512
N02AX02
ATC
tramadol; systemic, rectal
1.5
15.9
881
6868
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
11.3
15.7
29
26
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
3.6
15.2
69
197
J01DB01
ATC
cefalexin; oral
1.5
14.8
1713
15354
N02BE01
ATC
paracetamol; systemic, rectal
1.5
14.7
1814
16479
ZXA05
NOMESCO Finland
Left side
1.5
14.7
530
3750
M03BX02
ATC
tizanidine; oral
1.4
14.1
1265
10724
ZXA00
NOMESCO Finland
Right side
1.5
13.8
563
4091
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
13.2
556
4060
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
12.9
1400
12182
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
11.8
1097
9231
R03AC02
ATC
salbutamol; inhalant
1.4
11.7
1000
8291
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
3.5
11.3
52
152
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
11.0
389
2720
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
10.6
1169
10036
EP1DG
NOMESCO Finland
Very extensive examination of soft tissue of neck with high intesity magnet
5.7
10.6
29
51
C08CA01
ATC
amlodipine; oral
1.4
10.4
695
5499
D23.4
ICD-10 Finland
Benign neoplasm: Skin of scalp and neck
4.5
10.1
34
76
EP1CM
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with 3 Tesla magnet
14.6
10.0
16
11
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
2.7
10.0
68
261
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
9.7
1227
10689
B01AB05
ATC
enoxaparin; parenteral
1.4
9.7
583
4519
KMAK
NOMESCO Finland
NA
1.3
9.6
998
8447
NBR20
NOMESCO Finland
Intralesional or marginal excision of soft tissue tumour of shoulder or upper arm
12.4
9.4
16
13
D17.7
ICD-10 Finland
Benign lipomatous neoplasm of other sites
10.7
9.3
17
16
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.5
9.3
394
2855
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
9.2
1108
9550
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
8.9
402
2953
N03AX12
ATC
gabapentin; oral
1.5
8.8
286
1958
M54.5
ICD-10 Finland
Low back pain
1.4
8.5
609
4845
M01AH05
ATC
etoricoxib; oral
1.3
8.4
1169
10233
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.9
8.3
126
693
WZA90
NOMESCO Finland
Other doctors statement
1.4
8.3
418
3123
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.3
765
6315
VALMI
NOMESCO Finland
NA
1.4
8.3
434
3271
J01FA06
ATC
roxithromycin; oral
1.3
8.1
759
6278
D17.3
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
10.1
8.0
15
15
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
8.0
717
5891
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
7.9
1005
8658
J01AA02
ATC
doxycycline; systemic
1.3
7.8
1584
14522
QBJ00
NOMESCO Finland
Liposuction in trunk
6.4
7.7
19
30
WX002
NOMESCO Finland
Sedation and analgesia
1.4
7.7
372
2760
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.7
918
7840
P01AB01
ATC
metronidazole; oral, rectal
1.3
7.6
724
5984
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
7.6
196
1268
R22.2
ICD-10 Finland
Localized swelling, mass and lump, trunk
2.4
7.5
62
266
N03AX16
ATC
pregabalin; oral
1.4
7.5
436
3342
M79.6
ICD-10 Finland
Pain in limb
1.3
7.4
656
5364
R22.3
ICD-10 Finland
Localized swelling, mass and lump, upper limb
3.0
7.4
40
135
E66.8
ICD-10 Finland
Other obesity
2.0
7.4
89
453
A02BC05
ATC
esomeprazole; systemic
1.3
7.4
776
6502
J45.9
ICD-10 Finland
Asthma, unspecified
1.4
7.4
314
2274
G44.2
ICD-10 Finland
Tension-type headache
1.5
7.3
220
1477
UJF32
NOMESCO Finland
Coloscopy
1.4
7.3
488
3825
L16
ICPC
Ankle symptom/complaint
1.6
7.2
166
1046
J01DA01
ATC
[U] cefalexin; systemic
1.3
7.1
1228
10942
QAE00
NOMESCO Finland
Excision of loose skin or fold of skin from head and neck
7.9
7.1
15
19
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
7.1
609
4952
R01AD08
ATC
fluticasone; nasal
1.3
7.0
507
4018
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
6.9
439
3407
C09CA01
ATC
losartan; oral
1.4
6.9
439
3410
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.9
717
5985
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
6.9
178
1155
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
6.8
947
8199
R22
ICD-10 Finland
Localized swelling, mass and lump of skin and subcutaneous tissue
2.7
6.8
42
156
R51.80
ICD-10 Finland
Headache
1.5
6.8
237
1650
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.7
815
6940
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.6
694
5790
ENB99
NOMESCO Finland
Other excision of pharynx and adjacent structures
12.3
6.6
11
9
M04AA01
ATC
allopurinol; systemic
1.5
6.5
235
1644
R02
ICPC
Shortness of breath/dyspnoea
1.5
6.5
205
1392
QBA99
NOMESCO Finland
Other local destruction of skin of trunk
4.9
6.3
19
39
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.2
6.3
58
265
QX4AT
NOMESCO Finland
Ultrsound guided needle biopsy of skin
6.6
6.3
15
23
D21.9
ICD-10 Finland
Benign neoplasm: Connective and other soft tissue, unspecified
6.6
6.3
15
23
A98
ICPC
Health maint/preventive medicine
1.5
6.3
2062
19885
M01AB05
ATC
diclofenac; systemic, rectal
1.3
6.3
1318
11942
S29
ICPC
Skin symptom/complaint other
1.4
6.1
290
2141
R01AD09
ATC
mometasone; nasal
1.3
6.1
813
6974
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.5
6.1
230
1623
D11
ICPC
Diarrhoea
1.6
6.0
166
1092
J01CA04
ATC
amoxicillin; systemic
1.3
6.0
1575
14611

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
555
2692
2.37
63.10
1.3
1.3
—
—
—
0
0
1119
8328
1.63
29.87
2.2
2.1
—
—
—
0
0
2222
20636
1.74
15.68
15.6
14.6
24.5
24.4
mg/l
0.06
1817
16383
2054
18720
1.57
15.48
4.9
4.6
1.9
2.1
mu/l
1.13
1907
17091
2403
22955
2.55
15.06
23.1
21.4
250.8
247.4
e9/l
1.90
2352
22390
2404
22973
2.56
14.98
23.2
21.5
137.2
136.4
g/l
2.05
2379
22646
2289
21487
1.86
14.97
18.0
16.9
139.9
139.7
mmol/l
4.34
2251
20956
2404
22974
2.55
14.96
23.2
21.4
6.7
6.7
e9/l
0.19
2349
22340
2403
22965
2.53
14.87
23.0
21.3
90.9
91.2
fl
3.40
2376
22641
2403
22966
2.53
14.85
23.0
21.3
30.3
30.4
pg
2.55
2376
22640
2403
22968
2.53
14.81
23.1
21.4
4.6
4.5
e12/l
4.72
2348
22331
2293
21548
1.86
14.77
18.2
17.0
4.0
4.0
mmol/l
0.26
2249
20993
1721
15344
1.40
12.75
4.1
4.1
11.5
12.2
mm/h
1.46
1615
14204
2330
22127
1.89
12.75
18.7
17.1
79.2
79.3
umol/l
0.03
2330
22118
1588
14081
1.36
11.43
4.6
4.2
—
—
—
0
0
2324
22137
1.80
11.37
11.5
10.6
27.3
27.3
u/l
0.02
2252
21389
2270
21486
1.67
11.34
14.8
13.8
—
—
—
0
0
2084
19406
1.46
10.68
6.6
5.9
40.5
40.0
mmol/mol
1.17
1946
18002
2162
20294
1.51
10.50
5.0
4.6
6.0
6.0
mmol/l
1.17
1994
18503
1786
16227
1.36
10.34
7.9
7.7
78.3
78.2
u/l
0.02
1692
15326
1148
9799
1.32
10.23
3.9
4.1
—
—
—
0
0
2232
21131
1.57
10.03
5.3
5.0
2.8
2.7
mmol/l
0.16
2073
19481
1541
13823
1.30
9.00
3.1
3.2
54.0
52.2
u/l
0.24
1432
12864
1489
13310
1.30
8.85
4.5
4.3
1650.6
1893.0
e6/l
0.05
18
202
1699
15466
1.31
8.77
4.0
3.8
14.9
14.8
pmol/l
0.78
1575
14028
2191
20760
1.48
8.73
4.8
4.5
4.6
4.6
mmol/l
0.25
2053
19252
1190
10373
1.28
8.43
6.6
7.1
1.2
1.2
mmol/l
1.04
1044
8755
2176
20618
1.45
8.39
4.6
4.5
1.4
1.4
mmol/l
2.29
2021
19011
1876
17374
1.33
8.19
20.6
18.7
332.8
332.7
g/l
0.11
1866
17254
706
5765
1.31
8.19
2.9
3.1
—
—
—
0
0
1385
12338
1.28
8.10
5.1
5.0
6.9
6.8
mmol/l
1.10
1291
11602
1185
10371
1.27
7.95
5.4
5.9
0.0
0.0
e9/l
0.13
995
8989
1251
11023
1.27
7.93
6.3
6.4
11.7
11.6
umol/l
0.05
1196
10486
793
6620
1.29
7.71
2.3
2.5
—
—
—
0
0
1205
10596
1.27
7.67
5.3
6.0
1.9
1.9
e9/l
0.03
1052
9347
1176
10328
1.26
7.50
5.4
5.9
0.6
0.6
e9/l
0.75
991
8943
1627
14881
1.27
7.23
4.1
3.8
—
—
—
0
0
516
4118
1.32
6.90
3.8
3.8
291.4
436.9
ng/l
0.77
403
3264
1210
10728
1.25
6.88
5.6
6.1
0.2
0.2
e9/l
0.75
1055
9431
1340
12025
1.25
6.81
8.8
9.2
4.1
4.1
e9/l
0.19
1154
10529
563
4560
1.30
6.75
1.8
1.8
1.1
1.2
mg/l
0.62
434
3499
798
6780
1.26
6.48
4.1
4.0
7.3
8.9
mg/mmol
0.63
522
4329
1076
9461
1.24
6.44
5.8
6.3
1.2
1.2
mmol/l
0.59
987
8569
1988
18749
1.31
6.36
17.1
15.6
40.5
40.0
%
1.40
1361
13296
2101
19978
1.34
6.27
4.2
4.0
1.3
1.3
mmol/l
0.42
1942
18306
693
5831
1.26
6.04
3.9
4.5
—
—
—
0
0
318
2413
1.36
5.93
1.7
1.8
—
—
—
0
0
757
6449
1.25
5.90
3.5
3.3
355.0
305.2
mg/l
0.12
510
4127
1097
9739
1.23
5.79
5.7
6.4
8.5
8.8
%
1.53
1015
9122
1065
9429
1.23
5.77
5.5
6.2
0.7
0.7
%
0.46
983
8808
640
5365
1.26
5.71
4.2
4.0
91.4
89.4
%
1.18
624
5244
1091
9700
1.22
5.62
5.5
6.1
2.8
2.9
%
0.19
1008
9041
966
8488
1.23
5.57
2.0
2.0
96.7
95.1
pmol/l
0.45
504
4525
1116
9976
1.22
5.36
5.6
6.2
27.2
27.6
%
0.74
1024
9295
1102
9840
1.22
5.35
5.4
6.0
58.0
57.4
%
0.88
1017
9215
837
7274
1.23
5.31
3.9
3.7
64.3
106.1
e6/l
1.69
596
5267
749
6437
1.23
5.28
2.2
2.2
189.0
226.5
u/l
0.87
705
6045
1108
9909
1.21
5.27
3.9
3.6
0.0
0.0
estimate
0.50
167
1843
1108
9924
1.21
5.15
5.2
4.8
0.0
0.0
estimate
0.50
174
1882
209
1516
1.41
5.11
1.4
1.4
—
—
—
0
0
318
2473
1.33
5.03
1.4
1.4
—
—
—
0
0
192
1381
1.42
4.93
5.6
7.3
24.6
24.5
mmol/l
0.18
178
1292
1116
10031
1.20
4.92
3.9
3.6
0.0
0.0
estimate
1.08
165
1786
669
5718
1.23
4.91
3.0
2.7
1498.9
5087.9
umol/l
3.45
589
4967
262
1991
1.35
4.84
1.3
1.5
—
—
—
0
0
949
8422
1.21
4.74
5.1
4.8
2.9
2.6
ug/l
0.23
863
7584
131
886
1.51
4.63
5.1
5.7
1.6
1.6
%
0.18
122
828
130
878
1.51
4.63
5.1
5.8
0.9
0.9
%
0.58
121
823
774
6762
1.21
4.51
3.5
3.2
7.7
7.7
mmol/l
0.01
670
5678
760
6628
1.21
4.51
2.7
2.6
59.9
57.2
u/l
0.24
704
6131
80
485
1.67
4.50
5.8
8.0
105.5
105.4
mmol/l
0.06
73
431
80
485
1.67
4.50
5.8
8.0
11.2
11.3
mmol/l
0.14
73
431
298
2335
1.31
4.47
2.6
2.3
146.7
149.3
ug/g
0.04
242
1860
434
3571
1.26
4.44
3.0
2.8
1.3
1.0
e6/l
0.58
262
2071
1799
17004
1.21
4.31
19.2
17.8
13.7
13.7
%
0.38
1780
16630
84
522
1.63
4.31
5.0
4.5
—
—
—
0
0
103
676
1.55
4.21
5.3
6.9
1.2
1.3
mmol/l
1.35
93
588
702
6134
1.20
4.00
4.0
4.2
7.4
7.4
ph
1.21
101
1193
152
1094
1.41
3.94
2.5
2.4
—
—
—
0
0
1001
9039
1.18
3.90
5.3
5.0
35.6
35.4
g/l
0.44
935
8432
164
1201
1.39
3.85
7.8
11.0
—
—
—
0
0
267
2111
1.30
3.76
7.1
8.8
125.0
122.3
g/l
1.30
255
2038
231
1792
1.32
3.74
2.7
2.9
194.5
194.1
ng/l
0.01
211
1635
962
8680
1.18
3.74
9.8
9.5
1.3
1.3
inr
0.05
222
2441
720
6339
1.19
3.74
3.5
3.3
56.8
76.7
e6/l
0.53
558
4922
661
5781
1.20
3.69
3.5
3.2
0.4
0.4
e6/l
0.06
499
4390
311
2517
1.27
3.65
6.5
7.9
1.2
1.0
mmol/l
0.46
247
1975
192
1462
1.34
3.55
4.0
5.1
—
—
—
0
0
541
4660
1.21
3.55
3.8
3.5
—
—
—
0
0
514
4408
1.21
3.53
2.6
2.6
4.5
5.0
e6/l
0.46
442
3888
282
2273
1.27
3.43
6.7
8.3
94.9
95.6
%
0.78
269
2194
397
3340
1.22
3.30
3.2
3.0
3.0
1.9
e6/l
1.17
226
1844
140
1030
1.38
3.24
4.2
3.5
—
—
—
0
0
477
4107
1.20
3.12
3.1
2.7
553.5
556.9
mosm/kgh2o
0.12
406
3513
392
3319
1.22
3.05
1.3
1.2
5.4
12.2
u/ml
2.64
149
1292
408
3474
1.21
3.00
1.3
1.3
21.0
36.1
iu/ml
4.63
120
1096
305
2521
1.24
3.00
6.7
7.9
5.2
5.1
kpa
0.79
293
2411
305
2522
1.24
2.99
6.7
7.9
12.2
12.1
kpa
0.10
292
2414
484
4190
1.19
2.98
1.3
1.2
2.1
1.6
u/ml
0.25
133
1104
580
5107
1.18
2.92
2.2
2.4
—
—
—
0
0
218
1749
1.27
2.79
3.6
3.3
—
—
—
0
0
916
8383
1.15
2.74
2.8
2.8
125.7
146.9
ug/l
1.78
857
7740
146
1114
1.33
2.72
1.2
1.2
—
—
—
0
0
437
3779
1.19
2.72
1.8
1.7
1077.7
1181.2
nmol/l
1.73
354
2877
37
212
1.76
2.67
1.2
1.4
202838.3
66500.6
e6/l
0.55
27
149
360
3067
1.20
2.64
2.0
2.1
—
—
—
0
0
328
2772
1.21
2.61
29.9
24.6
1.3
1.3
inr
0.13
51
391
496
4356
1.17
2.56
4.6
3.9
1.0
1.0
kg/l
0.22
65
624
23
115
2.01
2.51
1.4
1.3
1.2
1.2
nmol/l
0.11
17
89
762
6933
1.14
2.43
3.8
3.4
2.3
2.4
mmol/l
0.67
664
6067
279
2350
1.21
2.32
1.4
1.3
—
—
—
0
0
36
215
1.68
2.29
1.4
1.4
27.3
28.3
u/l
0.06
29
172
119
907
1.33
2.28
1.7
1.9
—
—
—
0
0
585
5260
1.15
2.20
6.6
6.7
—
—
—
0
0
776
7110
1.13
2.19
5.4
5.9
—
—
—
0
0
622
5622
1.14
2.16
3.4
3.1
—
—
—
0
0
145
1152
1.27
2.07
3.1
3.4
4.6
4.5
pmol/l
0.38
127
1014
43
278
1.56
2.03
1.3
1.3
0.6
0.7
nmol/l
1.25
43
265
166
1344
1.25
2.03
1.3
1.2
—
—
—
0
0
38
239
1.60
2.01
1.3
1.3
—
—
nmol/l
—
0
0
281
2404
1.19
2.00
2.8
2.8
9.0
8.3
umol/l
0.19
247
2122
545
4907
1.14
2.00
3.0
3.0
0.7
0.7
ug/l
0.17
378
3228
216
1803
1.22
1.99
1.4
1.4
—
—
—
0
0
376
3301
1.16
1.96
2.5
2.1
30.6
29.9
s
1.28
362
3205
5
11
4.55
1.94
1.0
1.1
—
—
—
0
0
425
3771
1.15
1.92
3.5
3.1
2.4
2.5
mmol/l
1.23
365
3319
669
6118
1.13
1.92
2.9
3.0
1287.6
1323.3
ng/l
0.09
583
5220
22
122
1.81
1.84
1.6
3.0
7.4
7.4
ph
—
8
40
232
1968
1.20
1.83
3.1
2.4
33.0
61.4
u/l
0.63
196
1707
100
772
1.31
1.81
3.8
3.5
282.8
1945.9
u/ml
0.70
89
666
503
4541
1.14
1.77
4.4
4.7
—
—
—
0
0
143
1749
0.81
1.74
4.0
3.9
—
—
—
0
0
337
2965
1.16
1.72
1.3
1.2
—
—
—
0
0
317
2777
1.16
1.71
6.4
7.2
104.6
104.3
mmol/l
0.61
309
2708
254
2189
1.18
1.69
3.8
4.2
11.4
20.8
ug/l
0.90
203
1784
12
55
2.19
1.67
1.2
1.1
254.7
285.3
pmol/l
—
7
40
39
260
1.51
1.66
1.3
1.3
—
—
—
0
0
11
49
2.25
1.63
1.3
1.3
62.9
68.9
ug/l
—
5
22
97
759
1.29
1.62
2.6
2.3
558.8
502.9
ug/l
0.09
91
716
185
1560
1.20
1.58
1.3
1.3
—
—
—
0
0
675
6240
1.11
1.58
4.3
3.9
—
—
—
0
0
11
51
2.16
1.50
1.2
1.3
66.6
66.8
mu/l
—
6
39
36
242
1.49
1.50
1.4
1.4
295.3
284.6
pmol/l
0.06
26
190
116
939
1.25
1.49
1.7
1.7
—
—
—
0
0
174
1470
1.20
1.48
1.2
1.2
—
—
—
0
0
62
462
1.35
1.48
2.2
2.3
126.1
129.8
g/l
0.51
41
339
121
992
1.23
1.40
2.2
2.6
0.7
0.7
%
0.19
114
953
15
81
1.86
1.40
1.0
1.1
—
—
—
0
0
387
3496
1.13
1.36
3.0
3.4
0.8
0.8
mmol/l
0.61
370
3285
104
1275
0.81
1.35
1.9
1.9
1.3
1.4
g/l
0.23
97
1172
53
392
1.36
1.34
1.8
1.3
—
—
—
0
0
37
257
1.45
1.34
1.9
2.6
—
—
—
0
0
226
1976
1.16
1.30
3.8
3.7
5.8
5.8
kpa
0.06
217
1919
13
69
1.89
1.28
1.0
1.0
—
0.5
—
0
9
78
616
1.27
1.27
1.4
1.5
311.1
278.5
ug/g
0.52
37
368
5
118
0.42
1.24
1.0
1.3
—
—
—
0
0
522
4825
1.10
1.22
1.6
1.5
19.9
20.4
nmol/l
0.34
452
4122
11
56
1.97
1.22
1.2
1.2
—
—
—
0
0
69
540
1.29
1.21
1.5
1.7
31678.5
14430.6
e6/l
0.47
55
392
5
19
2.63
1.21
1.8
3.3
—
—
—
0
0
21
132
1.60
1.20
2.3
2.8
33.8
39.0
%
—
9
43
17
101
1.69
1.19
1.4
1.2
—
—
—
0
0
47
349
1.35
1.19
1.3
1.5
—
—
—
0
0
608
5671
1.10
1.18
1.8
1.7
1.4
1.4
mmol/l
0.02
547
4749
224
1974
1.15
1.17
3.9
3.7
2.0
1.9
mmol/l
0.18
180
1589
28
190
1.48
1.16
1.6
1.5
—
—
—
0
0
155
1330
1.18
1.15
2.7
3.2
133.0
129.2
g/l
1.25
147
1296
0
36
0.00
1.14
0.0
2.0
—
17.8
—
0
36
138
1613
0.85
1.12
2.4
2.8
10.7
10.6
g/l
0.06
132
1479
60
467
1.29
1.12
1.7
1.4
199.0
892.5
e6/l
1.22
52
378
60
467
1.29
1.12
1.6
1.4
17.3
28.9
e6/l
0.30
47
362
87
709
1.24
1.11
1.6
1.6
—
—
—
0
0
83
673
1.24
1.11
1.3
1.4
35.5
30.7
iu/l
0.57
74
571
185
1616
1.16
1.11
2.9
3.0
4.6
4.6
kpa
0.01
180
1563
59
459
1.29
1.11
2.7
1.8
0.8
0.8
nmol/l
0.22
47
385
35
251
1.40
1.10
3.4
3.1
2.5
26.3
nmol/l
0.56
35
245
70
558
1.26
1.09
2.2
2.4
58.3
114.4
ug/min
1.23
40
349
7
139
0.50
1.09
1.0
1.6
—
—
—
0
0
215
1902
1.14
1.08
2.7
2.2
354.8
367.7
nmol/l
0.50
201
1749
178
1554
1.16
1.08
4.4
4.0
86.5
93.1
ng/l
0.52
150
1366
210
1856
1.14
1.07
1.4
1.4
—
—
—
0
0
853
8106
1.08
1.06
3.8
3.6
35.0
50.5
ng/l
0.83
585
5707
47
357
1.32
1.05
3.4
3.5
—
—
—
0
0
33
237
1.40
1.04
3.3
6.6
7.2
7.5
mmol/l
0.22
28
199
955
9121
1.08
1.03
9.0
9.7
0.0
0.0
e9/l
0.87
766
7482
303
2750
1.12
1.02
1.3
1.3
533.7
503.6
titre
0.11
67
587
14
83
1.69
1.01
1.1
1.6
—
—
—
0
0
22
147
1.50
1.00
1.5
2.1
6.3
7.1
mmol/l
1.45
17
93
9
49
1.84
0.98
1.3
1.3
34.3
25.1
%
—
9
37
550
5150
1.09
0.98
2.3
2.2
2.8
3.0
mg/l
0.80
465
4386
102
860
1.19
0.96
1.1
1.1
—
—
—
0
0
0
32
0.00
0.95
0.0
1.1
—
71.5
—
0
27
36
478
0.75
0.95
5.1
4.8
2.6
2.5
mmol/l
0.03
29
328
573
5383
1.08
0.95
3.6
3.3
—
—
—
0
0
77
633
1.22
0.94
1.0
1.1
—
—
—
0
0
15
93
1.62
0.93
1.1
1.2
109.1
197.8
iu/ml
1.23
15
93
19
280
0.68
0.92
1.2
1.2
—
—
—
0
0
140
1218
1.16
0.92
1.2
1.2
177.3
155.5
iu/ml
0.17
52
440
212
1901
1.13
0.90
6.6
7.5
1.4
1.4
mmol/l
0.06
203
1835
58
465
1.25
0.90
1.5
1.9
4.1
4.9
iu/l
0.29
19
158
6
29
2.07
0.89
1.3
1.5
56.5
143.4
ng/l
—
6
29
13
79
1.65
0.88
1.1
1.1
1258.0
1540.1
miu/ml
0.53
13
79
242
2191
1.12
0.88
1.6
1.6
—
—
—
0
0
36
272
1.33
0.87
2.1
1.8
14.6
19.9
ug/l
2.16
36
267
30
403
0.74
0.87
1.4
1.3
—
—
—
0
0
84
997
0.84
0.86
1.6
1.8
1.6
1.5
g/l
0.36
71
864
24
170
1.42
0.85
1.1
1.0
0.5
0.4
u/ml
—
5
41
21
145
1.45
0.84
1.0
1.2
—
—
—
0
0
21
145
1.45
0.84
1.1
1.3
10.1
12.5
mmol/l
—
7
49
20
137
1.46
0.84
3.9
2.4
—
—
—
0
0
25
180
1.39
0.82
1.6
1.8
—
—
—
0
0
27
198
1.37
0.80
1.3
1.5
34.8
30.8
%
0.25
16
124
34
259
1.32
0.79
1.5
1.5
—
—
—
0
0
101
869
1.17
0.79
2.5
2.6
—
—
—
0
0
45
563
0.80
0.79
4.8
4.5
7.4
7.4
ph
0.30
35
471
38
295
1.29
0.78
1.1
1.1
0.2
1.6
u/ml
—
10
119
570
5396
1.07
0.78
4.4
3.9
0.0
0.0
estimate
1.08
168
1791
16
233
0.68
0.76
1.1
1.2
—
—
—
0
0
159
1420
1.13
0.75
8.0
9.7
0.7
0.7
%
0.21
159
1409
198
1794
1.11
0.74
8.5
9.0
—
—
—
0
0
21
150
1.40
0.73
1.3
2.3
21.1
14.2
%
—
7
53
21
150
1.40
0.73
1.3
1.2
—
—
—
0
0
60
497
1.21
0.73
1.3
1.3
9.3
9.3
u/l
0.01
53
404
115
1008
1.15
0.73
4.9
3.9
24.2
24.1
mmol/l
0.12
103
903
318
2953
1.09
0.72
1.6
1.7
—
—
—
0
0
15
218
0.69
0.71
1.3
1.6
—
—
—
0
0
69
582
1.19
0.70
1.1
1.2
—
—
—
0
0
213
1949
1.10
0.67
7.4
7.9
10.0
9.9
mmol/l
0.05
203
1853
67
567
1.19
0.67
2.5
3.2
25.3
25.0
mmol/l
0.20
57
497
34
267
1.28
0.67
1.1
1.1
2.4
4.4
u/ml
0.78
15
122
16
226
0.71
0.66
2.1
2.4
—
—
—
0
0
236
2172
1.10
0.66
1.5
1.6
—
—
—
0
0
17
236
0.72
0.64
2.2
2.2
—
—
—
0
0
79
681
1.17
0.64
3.1
4.1
3.9
3.9
mmol/l
0.30
74
636
29
371
0.78
0.64
1.1
1.4
62.4
61.3
mmol/l
0.05
23
296
14
95
1.48
0.64
1.2
1.5
—
—
—
0
0
135
1209
1.12
0.64
1.3
1.3
288.0
210.0
u/ml
0.48
127
1110
8
129
0.62
0.63
21.8
14.2
1052.3
815.5
nmol/l
—
8
124
205
1879
1.10
0.63
2.4
2.4
9.6
7.4
ug/l
0.51
188
1679
14
200
0.70
0.63
1.6
1.5
—
—
—
0
0
56
664
0.84
0.62
3.3
2.3
39.0
37.7
g/l
0.94
47
578
135
1499
0.89
0.61
2.6
2.5
—
—
—
0
0
73
630
1.16
0.60
3.0
3.4
—
—
—
0
0
529
5543
0.94
0.59
1.4
1.4
—
—
—
0
0
156
1416
1.11
0.59
8.1
9.8
92.6
93.9
%
1.12
156
1408
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
0
23
0.00
0.58
0.0
1.4
—
—
—
0
0
145
1313
1.11
0.58
2.7
2.8
—
—
—
0
0
159
1447
1.11
0.58
2.3
3.2
4.3
4.1
e9/l
0.42
124
1132
6
35
1.72
0.57
1.0
1.1
—
—
—
0
0
400
3786
1.07
0.57
1.4
1.5
2.4
2.5
g/l
0.69
229
2371
467
4444
1.06
0.57
1.7
1.7
29455890.0
32918673.2
pmol/l
0.04
404
3694
150
1364
1.11
0.56
3.4
3.7
7.4
7.4
ph
1.04
19
175
24
185
1.30
0.56
2.5
2.3
716.5
632.9
ml
0.64
17
120
16
217
0.74
0.55
1.1
1.2
—
—
—
0
0
300
2820
1.07
0.53
5.7
6.1
1.0
1.0
mmol/l
0.07
280
2624
51
433
1.18
0.52
1.5
1.4
—
—
—
0
0
10
66
1.52
0.52
1.0
1.3
—
—
—
0
0
154
1409
1.10
0.52
2.4
2.4
11.9
24.1
au/ml
—
8
69
151
1381
1.10
0.52
3.4
3.6
5.2
5.2
kpa
0.00
138
1287
14
100
1.40
0.51
1.0
2.5
695.4
1253.9
u/ml
0.94
14
100
140
1276
1.10
0.51
1.3
1.3
82.4
59.8
au/ml
—
6
59
57
490
1.17
0.51
2.4
3.0
31.1
37.4
umol/l
1.42
48
422
71
621
1.15
0.51
1.1
1.1
—
—
—
0
0
18
236
0.76
0.50
2.3
2.6
—
—
—
0
0
13
92
1.42
0.50
1.3
2.2
—
—
—
0
0
263
2468
1.07
0.50
1.5
1.6
—
—
—
0
0
39
465
0.84
0.49
1.5
1.7
—
—
—
0
0
61
530
1.15
0.49
2.5
2.1
—
—
—
0
0
54
465
1.16
0.48
2.0
2.2
—
—
—
0
0
16
119
1.35
0.48
5.8
6.4
—
—
—
0
0
62
541
1.15
0.47
2.5
2.2
—
—
—
0
0
107
1181
0.90
0.47
1.4
1.6
—
—
—
0
0
12
165
0.73
0.46
1.6
1.4
—
—
—
0
0
7
49
1.43
0.46
1.4
1.9
—
—
—
0
0
55
477
1.16
0.46
2.9
2.8
—
—
—
0
0
12
164
0.73
0.45
1.5
1.4
—
—
—
0
0
50
577
0.86
0.44
1.2
1.2
64.0
104.3
titre
—
5
49
32
265
1.21
0.44
1.3
1.6
66.9
60.7
%
0.34
14
172
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
7
51
1.37
0.44
1.1
1.1
—
—
—
0
0
15
197
0.76
0.44
1.4
1.5
—
—
—
0
0
28
229
1.23
0.44
1.8
1.4
—
—
—
0
0
17
219
0.77
0.43
1.2
1.2
—
—
—
0
0
97
878
1.11
0.43
3.2
4.7
—
—
—
0
0
31
257
1.21
0.43
1.1
1.1
0.4
1.4
u/ml
—
10
98
5
31
1.61
0.43
1.2
1.3
—
—
—
0
0
8
56
1.43
0.42
2.8
1.5
—
—
—
0
0
16
122
1.31
0.42
1.3
1.0
—
—
—
0
0
113
1033
1.10
0.42
2.7
3.4
25.3
25.3
mmol/l
0.06
108
1002
15
195
0.77
0.41
1.3
1.5
6.1
6.8
g/l
—
8
133
15
195
0.77
0.41
1.3
1.5
3.1
3.0
g/l
—
7
132
15
195
0.77
0.41
1.3
1.5
0.6
0.4
g/l
—
8
132
0
16
0.00
0.41
0.0
1.3
—
1.7
—
0
9
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
46
529
0.87
0.40
1.6
1.7
—
—
—
0
0
61
540
1.13
0.40
2.4
2.2
—
—
—
0
0
87
788
1.11
0.39
1.9
2.0
22.2
21.5
s
0.27
80
700
100
913
1.10
0.39
1.2
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.2
—
—
—
0
0
23
187
1.23
0.39
1.1
1.0
7.3
2.1
u/ml
0.61
11
63
9
67
1.34
0.38
1.6
1.3
70.6
142.0
nmol/l
—
9
52
8
114
0.70
0.37
1.8
1.6
4.4
4.1
u/field
—
8
86
150
1399
1.08
0.37
1.4
1.4
—
—
—
0
0
13
169
0.77
0.37
1.5
1.4
—
—
—
0
0
57
506
1.13
0.37
2.5
2.3
—
—
—
0
0
62
693
0.89
0.37
4.7
3.7
130.4
71.9
mg/l
0.31
49
557
9
71
1.27
0.36
4.9
5.1
—
—
—
0
0
9
71
1.27
0.36
1.0
1.0
—
—
—
0
0
76
688
1.11
0.36
12.4
9.7
—
—
—
0
0
60
536
1.12
0.35
2.5
2.2
—
—
—
0
0
20
162
1.24
0.35
1.3
1.2
2.6
2.0
mmol/l
0.95
20
155
26
217
1.20
0.35
1.9
1.5
—
—
—
0
0
13
99
1.31
0.35
3.3
14.0
—
—
—
0
0
10
73
1.37
0.34
1.9
1.5
—
—
—
0
0
26
308
0.84
0.34
1.3
1.3
—
—
—
0
0
29
247
1.18
0.33
3.0
2.9
—
—
—
0
0
19
155
1.23
0.32
1.2
1.0
—
—
—
0
0
10
74
1.35
0.32
1.6
2.4
—
—
—
0
0
6
47
1.28
0.32
1.0
1.1
—
4.2
—
0
6
41
360
1.14
0.32
1.3
1.4
—
—
—
0
0
10
132
0.76
0.32
1.2
1.1
—
—
—
0
0
82
752
1.09
0.31
1.2
1.2
0.4
0.8
u/ml
—
6
68
45
399
1.13
0.31
4.0
3.1
0.9
0.8
nmol/l
0.20
39
311
61
673
0.90
0.30
4.7
3.7
1.3
1.8
ratio
—
5
52
46
409
1.13
0.30
2.6
2.9
—
—
—
0
0
172
1629
1.06
0.29
3.8
4.0
0.6
0.6
%
0.22
38
384
315
3033
1.04
0.29
2.4
2.6
2.4
2.3
g/l
1.84
305
2832
63
691
0.91
0.29
4.6
3.7
42.9
64.2
mg/l
1.09
48
555
8
110
0.73
0.28
1.6
1.8
—
—
—
0
0
339
3272
1.04
0.28
2.5
2.6
12.7
13.1
umol/l
0.66
323
3051
11
85
1.30
0.28
2.5
2.5
—
—
—
0
0
15
122
1.23
0.27
1.3
1.6
—
—
—
0
0
41
458
0.89
0.26
3.1
2.6
15.5
16.2
%
0.49
26
235
24
206
1.17
0.26
1.1
1.0
2.7
2.1
u/ml
—
10
72
5
73
0.68
0.26
2.0
1.8
—
—
—
0
0
167
1591
1.05
0.25
4.0
4.2
0.0
0.3
%
0.75
37
412
296
2859
1.04
0.25
2.5
2.6
21.7
23.2
%
1.18
251
2457
54
493
1.10
0.24
1.4
1.2
176.4
205.1
miu/ml
0.19
22
202
27
308
0.88
0.24
2.1
2.5
4.0
231.0
u/ml
0.97
27
296
16
133
1.20
0.24
1.6
1.9
11.8
5.4
umol/l
0.42
16
85
19
161
1.18
0.24
1.1
1.0
295.5
312.8
ng/l
0.15
13
105
19
161
1.18
0.24
1.0
1.0
807.6
691.0
ng/l
—
10
103
191
1830
1.05
0.23
2.3
2.2
13.0
13.3
nmol/l
0.19
170
1619
195
2032
0.96
0.23
2.1
2.2
0.2
0.2
g/l
0.41
183
1903
38
342
1.11
0.23
1.2
1.1
5.6
1700.4
iu/ml
—
7
77
17
200
0.85
0.22
1.0
1.2
—
—
—
0
0
187
1796
1.04
0.21
3.8
4.1
0.8
0.9
%
0.15
47
535
0
11
0.00
0.21
0.0
1.2
—
12.3
—
0
11
0
10
0.00
0.21
0.0
7.5
—
—
—
0
0
19
220
0.86
0.21
1.5
1.4
10314.4
107449.8
e6/l
1.82
12
129
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
8
102
0.78
0.21
3.0
2.7
—
—
—
0
0
20
230
0.87
0.21
1.5
1.3
285.3
278.3
mosm/kgh2o
1.18
20
173
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
106
1004
1.06
0.20
3.6
3.7
—
—
—
0
0
24
211
1.14
0.20
2.3
2.3
—
—
—
0
0
17
145
1.17
0.20
1.5
1.4
—
—
—
0
0
31
345
0.90
0.20
1.0
1.1
—
—
—
0
0
35
316
1.11
0.20
1.3
1.2
4.3
5.3
u/ml
0.16
19
136
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
165
1719
0.96
0.20
3.9
4.0
1.2
1.2
mmol/l
0.75
149
1501
13
108
1.20
0.20
1.5
2.6
—
—
—
0
0
28
313
0.89
0.20
2.9
2.6
—
—
—
0
0
171
1779
0.96
0.20
2.7
2.7
66.2
66.6
g/l
0.31
157
1635
27
302
0.89
0.19
1.1
1.1
—
—
—
0
0
46
423
1.09
0.19
2.3
2.2
—
—
—
0
0
40
366
1.09
0.19
1.5
1.2
—
—
—
0
0
55
511
1.08
0.19
1.2
1.2
—
—
—
0
0
7
58
1.21
0.18
1.3
1.0
—
—
—
0
0
70
744
0.94
0.18
3.6
3.3
0.2
0.3
g/l
0.67
32
309
7
59
1.19
0.18
1.0
1.1
—
—
—
0
0
96
913
1.05
0.17
1.8
2.0
3.8
2.1
ug/l
0.43
85
815
220
2133
1.03
0.17
4.1
4.3
—
—
—
0
0
40
368
1.09
0.17
1.1
1.2
17.0
44.6
u/l
2.50
33
316
23
205
1.12
0.17
3.4
3.0
66.9
39.6
mg/l
0.35
17
157
20
177
1.13
0.16
1.5
2.2
—
46.2
—
0
21
36
391
0.92
0.16
1.1
1.2
375.5
275.5
u/ml
0.70
24
238
23
206
1.12
0.16
1.4
1.5
—
—
—
0
0
29
318
0.91
0.15
1.3
1.2
—
—
—
0
0
17
193
0.88
0.15
1.1
1.2
—
—
—
0
0
32
293
1.09
0.15
3.0
2.6
—
—
—
0
0
16
141
1.14
0.14
1.1
1.1
—
—
—
0
0
8
97
0.82
0.13
2.0
2.9
—
—
—
0
0
36
387
0.93
0.13
1.5
1.6
—
—
—
0
0
40
428
0.93
0.13
1.2
1.4
—
—
—
0
0
51
481
1.06
0.13
2.6
2.9
8.3
8.0
kpa
0.61
45
442
20
221
0.90
0.12
2.9
3.4
64.4
55.8
%
0.69
13
147
23
252
0.91
0.12
1.3
1.2
—
—
—
0
0
26
239
1.09
0.12
1.1
1.0
1.1
2.4
u/ml
—
10
51
23
210
1.10
0.12
3.1
3.3
—
—
—
0
0
24
220
1.09
0.11
1.2
1.4
0.2
0.3
nmol/l
0.32
19
168
115
1188
0.97
0.11
1.5
1.5
—
—
—
0
0
18
199
0.90
0.11
1.0
1.2
—
—
—
0
0
28
302
0.93
0.11
1.1
1.1
—
—
—
0
0
174
1699
1.03
0.10
4.0
4.2
0.2
0.1
%
0.35
45
490
11
96
1.15
0.10
1.3
1.2
—
—
—
0
0
23
249
0.92
0.10
1.1
2.0
—
1076.4
—
0
11
11
125
0.88
0.10
1.3
1.0
—
—
—
0
0
14
156
0.90
0.10
1.0
1.0
—
—
—
0
0
5
47
1.06
0.09
1.4
1.9
—
—
—
0
0
23
247
0.93
0.08
3.3
4.1
—
—
—
0
0
6
57
1.05
0.08
1.5
1.5
—
—
—
0
0
5
60
0.83
0.08
1.0
1.6
—
—
—
0
0
5
62
0.81
0.08
2.4
2.2
—
—
—
0
0
7
65
1.08
0.08
2.1
1.6
—
—
—
0
0
11
98
1.12
0.07
1.1
1.1
—
—
—
0
0
6
74
0.81
0.07
1.0
1.1
—
—
—
0
0
16
174
0.92
0.07
1.3
1.1
—
69.0
—
0
7
6
75
0.80
0.07
1.0
1.0
—
—
—
0
0
54
520
1.04
0.07
1.1
1.2
2.1
3.4
u/ml
—
6
48
8
76
1.05
0.07
4.1
7.5
22.8
25.0
mmol/l
—
8
69
36
343
1.05
0.07
1.0
1.1
—
—
—
0
0
56
580
0.96
0.07
1.1
1.2
—
—
—
0
0
9
86
1.05
0.07
1.1
1.9
2794.2
113.2
ug/l
—
9
74
119
1165
1.02
0.07
9.7
10.4
24.3
24.3
mmol/l
0.12
113
1096
45
468
0.96
0.07
3.7
4.0
—
—
—
0
0
8
90
0.89
0.06
2.0
3.0
—
—
—
0
0
8
92
0.87
0.06
1.3
1.2
—
0.1
g/l
—
0
9
246
2429
1.01
0.06
1.8
2.7
1.7
1.8
%
1.18
217
2170
41
394
1.04
0.06
1.3
1.6
—
—
—
0
0
13
119
1.09
0.06
1.3
2.5
—
—
—
0
0
16
172
0.93
0.06
1.4
1.3
—
—
—
0
0
25
237
1.06
0.05
1.1
1.1
—
—
—
0
0
20
188
1.06
0.05
2.4
1.8
11.6
11.4
%
0.05
20
188
47
455
1.03
0.05
2.7
3.6
35.0
27.2
mg/l
0.39
25
283
10
110
0.91
0.05
1.0
1.6
—
—
—
0
0
19
179
1.06
0.05
1.7
1.5
—
—
—
0
0
30
288
1.04
0.04
1.3
2.2
—
3.5
—
0
6
22
209
1.05
0.04
1.2
1.1
—
—
—
0
0
51
524
0.97
0.04
4.4
3.9
—
—
—
0
0
13
121
1.07
0.03
1.2
1.4
—
—
—
0
0
35
360
0.97
0.03
2.5
3.5
0.9
1.5
%
0.93
26
287
37
380
0.97
0.03
1.2
1.4
93.2
117.2
u/ml
—
6
71
25
259
0.96
0.02
1.1
1.3
—
—
—
0
0
739
7411
1.00
0.02
3.1
2.9
—
—
—
0
0
181
1822
0.99
0.02
1.9
2.7
68.2
70.9
e9/l
0.57
143
1391
10
107
0.93
0.02
10.3
11.0
0.6
0.6
mmol/l
—
10
100
40
408
0.98
0.01
4.0
3.5
4.1
4.2
e9/l
0.18
40
408
31
317
0.98
0.01
1.3
1.7
0.6
0.8
g/l
0.73
22
240
35
357
0.98
0.01
1.4
1.3
—
—
—
0
0
36
354
1.02
0.00
5.1
3.3
—
—
—
0
0
43
424
1.01
0.00
4.1
3.8
59.2
57.7
%
0.41
43
424
11
115
0.96
0.00
1.1
1.3
149.9
142.7
nmol/l
0.15
11
115
12
125
0.96
0.00
3.2
3.6
—
—
—
0
0
15
155
0.97
0.00
1.7
1.3
2.0
0.9
u/ml
—
7
74
11
109
1.01
0.00
1.2
1.6
—
10.1
—
0
8
36
361
1.00
0.00
1.7
2.2
198.3
3142.3
u/l
2.88
14
141
12
116
1.03
0.00
1.2
1.2
—
—
—
0
0
26
256
1.02
0.00
1.2
1.6
—
—
—
0
0
26
256
1.02
0.00
1.2
1.6
—
—
—
0
0
26
256
1.02
0.00
1.2
1.6
—
—
—
0
0
26
256
1.02
0.00
1.2
1.6
—
—
—
0
0
19
188
1.01
0.00
2.7
2.0
—
1.7
—
0
8
0
5
0.00
0.00
0.0
1.2
—
174.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
569.7
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
1187.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
46.1
—
0
5
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
6
68
0.88
0.00
2.3
2.6
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
5
55
0.91
0.00
1.6
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
0.00
1.3
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
6
69
0.87
0.00
2.5
2.4
0.6
1.2
ug/l
—
6
61
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
6
69
0.87
0.00
1.3
2.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
9
91
0.99
0.00
1.6
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
6
69
0.87
0.00
1.2
1.5
19.0
26.8
%
—
6
63
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
52
520
1.00
0.00
1.1
1.2
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_LIPO_SKIN_HEADFACENECK and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_LIPO_SKIN_HEADFACENECK 0.978 [0.87, 1.09] 0.695
Birth year 0.993 [0.99, 1.0] 0.116

During the follow-up period (1.1.1998 — 31.12.2019), 693 out of 6575 females with CD2_BENIGN_LIPO_SKIN_HEADFACENECK died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_LIPO_SKIN_HEADFACENECK 1.012 [0.91, 1.13] 0.832
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1221 out of 8836 males with CD2_BENIGN_LIPO_SKIN_HEADFACENECK died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_LIPO_SKIN_HEADFACENECK.

N-year risk Females Males
1 0.086% 0.145%
5 0.476% 1.003%
10 1.341% 2.612%
15 2.47% 4.84%
20 4.234% 8.152%

Relationships between endpoints

Index endpoint: CD2_BENIGN_LIPO_SKIN_HEADFACENECK – Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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