Disorder of external ear, unspecified

H8_EXTDISINOTH

auditory system disease: Pathological processes of the ear, the hearing, and the equilibrium system of the body.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H62*
  • Cause of death: ICD-10 H62*

2 out of 7 registries used, show all original rules.

1149

4. Check minimum number of events

None

1149

5. Include endpoints

None

1149

6. Filter based on genotype QC (FinnGen only)

1149

Control definitions (FinnGen only)

Control exclude
H8_EXTERNAL

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7369 3573 3766
Only index persons 7023 3453 3570
Unadjusted period prevalence (%)
Whole population 0.10 0.10 0.11
Only index persons 0.13 0.13 0.14
Median age at first event (years)
Whole population 57.40 57.69 57.22
Only index persons 57.52 57.75 57.29

-FinnGen-

Key figures

All Female Male
Number of individuals 1149 607 542
Unadjusted period prevalence (%) 0.22 0.21 0.24
Median age at first event (years) 58.67 56.65 60.93

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1023
Matched controls
10228
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H62.0*A46
ICD-10 Finland
Otitis externa in erysipelas
5134.9
323.0
774
6
A46
ICD-10 Finland
Erysipelas
12.2
238.0
508
763
H62.0
ICD-10 Finland
Otitis externa in bacterial diseases classified elsewhere
965.6
171.1
163
*
H60.9
ICD-10 Finland
Otitis externa, unspecified
13.5
132.0
243
230
H60.8
ICD-10 Finland
Other otitis externa
25.3
81.0
115
51
H60.3
ICD-10 Finland
Other infective otitis externa
29.0
78.4
107
41
J01DB01
ATC
cefalexin; oral
5.2
65.4
942
7072
H62.1*B02.8
ICD-10 Finland
Otitis externa in zoster
657.2
63.5
62
*
H60.1
ICD-10 Finland
Cellulitis of external ear
34.1
58.3
76
24
H60
ICD-10 Finland
Otitis externa
7.6
46.8
114
165
H01
ICPC
Ear pain/earache
4.0
39.3
173
494
H62.2
ICD-10 Finland
Otitis externa in mycoses
+∞
37.7
36
*
H29
ICPC
Ear symptom/complaint other
3.8
35.1
163
485
S76
ICPC
Skin infection other
5.2
34.9
114
240
J01FF01
ATC
clindamycin; systemic
2.4
31.4
344
1780
H62.2*B36.9
ICD-10 Finland
Otomycosis NOS
+∞
28.3
27
*
J01DA01
ATC
[U] cefalexin; systemic
2.1
27.3
680
4972
D07AB02
ATC
hydrocortisone butyrate; topical
2.2
26.5
342
1884
D07AC01
ATC
betamethasone; topical
2.1
25.6
398
2371
UDC00
NOMESCO Finland
Ear microscopy
3.7
25.3
116
338
H62.1*B00.19
ICD-10 Finland
Otitis externa in herpesviral [herpes simplex] infection
+∞
25.1
24
*
S02CA02
ATC
flumetasone and antiinfectives; otic
4.2
23.4
92
234
H70
ICPC
Otitis externa
7.7
22.2
52
71
H04
ICPC
Ear discharge
5.2
21.7
69
141
J01CE08
ATC
benzathine benzylpenicillin; parenteral
13.2
21.3
37
29
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.6
21.2
167
703
J01CE02
ATC
phenoxymethylpenicillin; oral
1.9
21.2
724
5667
B02.8
ICD-10 Finland
Zoster with other complications
34.6
21.2
27
8
H60.0
ICD-10 Finland
Abscess of external ear
49.1
20.2
24
5
H62.2*B44.8
ICD-10 Finland
Otitis externa in aspergillosis
+∞
19.9
19
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
19.3
456
3093
SPAT1255
SPAT
Intravenous administration of medicine
3.4
19.1
96
301
E0000UV
ATC
NA
1.9
18.7
414
2736
H61.0
ICD-10 Finland
Perichondritis of external ear
193.4
18.6
19
*
D07AC13
ATC
mometasone; topical
1.9
17.5
311
1888
D07XC01
ATC
betamethasone, combinations; topical
2.5
17.4
153
683
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.5
17.4
83
250
D07AA02
ATC
hydrocortisone; topical
2.4
17.3
162
746
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
7.7
16.5
38
51
J05AB11
ATC
valaciclovir; oral
2.3
16.2
160
757
H61.2
ICD-10 Finland
Impacted cerumen
4.0
16.1
65
170
N02BE01
ATC
paracetamol; systemic, rectal
2.0
15.9
866
7500
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
15.7
519
3829
H62.2*B37.2
ICD-10 Finland
Otitis externa in candidiasis
+∞
15.7
15
*
D07CC01
ATC
betamethasone and antibiotics; topical
2.3
15.3
150
706
H66.9
ICD-10 Finland
Otitis media, unspecified
3.5
14.0
67
203
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
13.9
191
1041
H62.1
ICD-10 Finland
Otitis externa in viral diseases classified elsewhere
+∞
13.6
13
*
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.5
13.4
112
484
R50.9
ICD-10 Finland
Fever, unspecified
2.1
13.2
152
769
H60.5
ICD-10 Finland
Acute otitis externa, noninfective
12.4
13.1
23
19
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
12.2
238
1468
TDA90
NOMESCO Finland
Removal wax from ear
8.3
12.1
26
32
D06AX01
ATC
fusidic acid; topical (antibiotics for topical use)
2.3
11.8
111
511
J01MA02
ATC
ciprofloxacin; systemic
1.6
11.8
383
2741
S29
ICPC
Skin symptom/complaint other
2.0
11.7
173
963
H66.3
ICD-10 Finland
Other chronic suppurative otitis media
16.6
11.7
18
11
E000001
ATC
NA
1.8
11.6
214
1291
G51.0
ICD-10 Finland
Bell palsy
4.4
11.5
41
97
H13
ICPC
Plugged feeling ear
1.9
11.4
176
997
L20.0
ICD-10 Finland
Besnier prurigo
2.8
11.4
74
277
SPAT1263
SPAT
Sampling
1.6
11.1
410
3021
R06AE07
ATC
cetirizine; oral
1.6
11.0
413
3050
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
10.5
188
1119
H62.4*L01.0
ICD-10 Finland
Otitis externa in impetigo
+∞
10.4
10
*
J01CA04
ATC
amoxicillin; systemic
1.6
10.3
784
6827
L73.2
ICD-10 Finland
Hidradenitis suppurativa
8.9
10.3
21
24
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
10.2
207
1284
S03CA04
ATC
hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
3.7
10.0
43
121
AA1AD
NOMESCO Finland
CT of head and brain
1.7
9.9
230
1485
L03.2
ICD-10 Finland
Cellulitis of face
9.7
9.8
19
20
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.0
9.6
132
715
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.9
9.5
135
741
S03CA01
ATC
dexamethasone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)
3.8
9.4
38
102
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.7
9.0
38
106
G47.3
ICD-10 Finland
Sleep apnoea
1.7
8.9
217
1417
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
8.8
254
1733
H61.8
ICD-10 Finland
Other specified disorders of external ear
14.2
8.7
14
10
H02AB06
ATC
prednisolone; systemic
1.5
8.7
438
3411
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
5.6
8.6
24
44
H60.4
ICD-10 Finland
Cholesteatoma of external ear
27.8
8.5
11
*
D07BC01
ATC
betamethasone and antiseptics; topical
1.9
8.5
127
711
N02AX02
ATC
tramadol; systemic, rectal
1.5
8.5
399
3056
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
8.3
528
4299
ZXA10
NOMESCO Finland
Bilateral
1.7
8.2
173
1079
H81
ICPC
Excessive ear wax
1.8
8.1
148
884
D07AD01
ATC
clobetasol; topical
1.8
8.0
157
957
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
8.0
307
2237
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.6
8.0
262
1841
L08.9
ICD-10 Finland
Local infection of skin and subcutaneous tissue, unspecified
3.6
8.0
34
96
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.7
8.0
52
198
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.4
8.0
67
291
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
8.0
147
882
DC1AD
NOMESCO Finland
Temporalbone CT
7.3
8.0
18
25
D11AH01
ATC
tacrolimus; topical
7.3
8.0
18
25
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.6
7.9
269
1908
B02.9
ICD-10 Finland
Zoster without complication
2.5
7.9
61
256
H02AB07
ATC
prednisone; oral
1.8
7.9
134
783
D07AB08
ATC
desonide; topical
1.9
7.8
108
588
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.8
7.7
131
761
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
7.7
78
371
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
7.7
318
2354
R42
ICD-10 Finland
Dizziness and giddiness
1.6
7.6
193
1268
S06
ICPC
Rash localized
2.4
7.6
62
268
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
7.5
104
566
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
7.4
115
651
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
7.4
105
577
S01
ICPC
Pain/tenderness of skin
2.7
7.3
47
177
SPAT1254
SPAT
Administration of medicine
1.8
7.3
133
793
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
7.3
103
564
M94.1
ICD-10 Finland
Relapsing polychondritis
+∞
7.3
7
*
H620, A499
ICD-10 Finland
NA
+∞
7.3
7
*
Z71.8
ICD-10 Finland
Other specified counselling
1.6
7.3
223
1539
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
7.2
77
375
H65.3
ICD-10 Finland
Chronic mucoid otitis media
4.1
7.2
26
64
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.7
7.2
145
893
N05AA02
ATC
levomepromazine; systemic
2.7
7.2
46
173
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.8
7.2
128
758
M79.6
ICD-10 Finland
Pain in limb
1.5
7.2
323
2429
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
7.0
431
3447
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.5
7.0
50
203
T82
ICPC
Obesity
3.0
7.0
38
131
J01MA12
ATC
levofloxacin; systemic
1.6
7.0
173
1129
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
6.9
155
986
E66.01
ICD-10 Finland
Obesity due to excess calories
2.1
6.9
77
386
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.3
6.8
32
99
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
6.8
358
2771
L21
ICD-10 Finland
Seborrhoeic dermatitis
4.6
6.8
22
49
S70
ICPC
Herpes zoster
3.4
6.8
31
94
N03AX09
ATC
lamotrigine; oral
2.4
6.8
52
219
H65.0
ICD-10 Finland
Acute serous otitis media
4.7
6.7
21
45
D01AC02
ATC
miconazole; topical
2.1
6.7
76
382
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
6.7
137
848
H70.0
ICD-10 Finland
Acute mastoiditis
22.7
6.7
9
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
6.6
47
190
T90
ICPC
Diabetes non-insulin dependent
1.6
6.6
205
1417
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.1
6.6
75
379
ZXA05
NOMESCO Finland
Left side
1.5
6.6
221
1554
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.5
175
1167
DFF00
NOMESCO Finland
Pure tone audiometry
2.0
6.5
84
445
E66.8
ICD-10 Finland
Other obesity
2.4
6.4
53
232
WX110
NOMESCO Finland
Local anesthesy
1.4
6.4
643
5584
H61.3
ICD-10 Finland
Acquired stenosis of external ear canal
70.3
6.4
7
*
J01DA06
ATC
[U] cefuroxime; systemic
1.7
6.4
136
850
A10BA02
ATC
metformin; oral
1.5
6.4
244
1763
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.8
6.4
39
145
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
6.4
104
599
H92.0
ICD-10 Finland
Otalgia
2.6
6.4
45
181
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
6.3
124
756
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.6
6.3
42
164
R51.80
ICD-10 Finland
Headache
1.7
6.3
122
743
J01AA02
ATC
doxycycline; systemic
1.4
6.3
743
6641
S18
ICPC
Laceration/cut
1.4
6.2
375
2966
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.6
6.2
179
1213
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
6.2
37
135
EBA10
NOMESCO Finland
Surgical removal of tooth
1.8
6.2
103
597
N03AX16
ATC
pregabalin; oral
1.5
6.2
209
1467
K02.1
ICD-10 Finland
Caries of dentine
1.4
6.2
520
4365
J01FA09
ATC
clarithromycin; systemic
1.5
6.2
283
2126
H71
ICD-10 Finland
Cholesteatoma of middle ear
5.4
6.2
17
32
SPAT1260
SPAT
Consultation of another employee
1.6
6.2
161
1066
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.5
6.2
219
1557
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.8
6.1
36
130
C03CA01
ATC
furosemide; systemic
1.5
6.1
232
1674
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
4.7
6.1
19
41
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
6.1
60
285
H70.1
ICD-10 Finland
Chronic mastoiditis
12.6
6.1
10
8
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.5
6.1
198
1382
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.1
366
2897
J01FA06
ATC
roxithromycin; oral
1.4
6.0
368
2918
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
5.2
6.0
17
33
N06AX16
ATC
venlafaxine; oral
1.7
6.0
121
743

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
355
1058
4.41
108.42
2.3
1.7
—
—
—
0
0
529
2559
2.98
70.48
4.4
4.2
—
—
—
0
0
679
4835
1.99
27.70
7.7
5.9
0.2
0.2
e9/l
1.21
596
4285
1089
9461
3.89
26.37
21.9
13.9
25.3
24.1
mg/l
0.75
1001
7473
650
4662
1.91
24.80
7.2
5.6
0.6
0.6
e9/l
1.21
576
4052
726
5406
1.93
24.62
12.4
9.0
4.2
4.1
e9/l
0.50
644
4757
229
1141
2.26
24.36
2.0
1.4
—
—
—
0
0
650
4681
1.89
24.28
7.3
5.6
0.0
0.0
e9/l
0.58
572
4073
659
4785
1.88
23.80
7.4
5.7
1.9
2.0
e9/l
0.53
587
4237
719
5506
1.82
20.44
5.4
4.9
6.8
6.7
mmol/l
0.36
682
5161
466
3141
1.81
20.37
7.1
5.7
—
—
—
0
0
366
2319
1.85
19.38
9.2
6.6
—
—
—
0
0
1090
9760
3.27
19.26
23.5
15.9
139.6
139.7
mmol/l
0.23
1065
9504
248
1396
1.99
18.72
2.4
2.1
—
—
—
0
0
1090
9793
3.20
18.48
23.7
16.0
4.0
4.0
mmol/l
0.56
1063
9526
579
4241
1.74
18.40
7.4
5.8
0.7
0.7
%
0.91
543
3981
596
4404
1.73
18.33
7.8
6.1
8.6
8.6
%
0.01
561
4148
565
4115
1.73
18.29
6.8
6.2
1.2
1.2
mmol/l
0.05
524
3755
592
4384
1.72
17.91
7.4
5.8
3.1
2.9
%
1.39
553
4103
516
3706
1.71
17.24
2.2
2.0
94.1
94.8
pmol/l
0.11
293
1945
602
4510
1.70
17.18
7.6
5.9
27.1
27.9
%
1.09
563
4224
595
4449
1.70
17.06
7.3
5.7
57.5
57.2
%
0.28
557
4189
605
4566
1.69
16.57
8.5
6.9
1.2
1.2
mmol/l
0.39
517
3864
869
7274
1.80
15.94
9.5
7.6
81.7
77.5
u/l
0.76
819
6839
531
3951
1.64
14.76
6.3
4.9
35.2
35.6
g/l
0.86
499
3686
146
738
2.12
14.56
7.3
8.9
—
—
—
0
0
980
8632
1.92
13.74
5.2
4.6
2.2
1.9
mu/l
0.63
896
7928
316
2091
1.71
13.59
1.6
1.7
1.0
1.1
mg/l
0.46
243
1585
345
2339
1.68
13.54
4.5
3.8
89.3
90.6
%
0.43
335
2284
503
3768
1.60
13.10
10.9
9.3
1.2
1.2
inr
0.60
138
1099
628
4958
1.59
13.05
7.1
6.4
12.3
11.5
umol/l
0.29
601
4704
332
2252
1.67
12.90
2.6
2.3
—
—
—
0
0
742
6102
1.61
12.90
5.1
4.3
1808.0
2156.8
e6/l
—
5
99
229
1421
1.76
12.25
1.9
2.1
29.5
29.7
s
0.17
221
1379
816
6930
1.61
11.81
4.8
4.0
14.1
11.9
mm/h
4.26
760
6425
839
7179
1.63
11.72
4.3
3.9
14.5
14.8
pmol/l
3.24
776
6554
405
2947
1.58
11.57
2.8
2.4
—
—
—
0
0
241
1544
1.71
11.44
2.8
2.7
1.0
1.1
e6/l
0.07
146
876
765
6432
1.57
11.25
5.0
4.2
—
—
—
0
0
89
410
2.27
11.14
3.3
3.6
24.2
24.2
mmol/l
0.08
80
369
251
1643
1.68
10.95
1.7
1.7
1242.6
1196.6
nmol/l
0.30
187
1252
416
3077
1.55
10.91
3.6
3.5
2.4
2.4
mmol/l
0.28
365
2713
305
2114
1.60
10.54
4.2
3.5
—
—
—
0
0
374
2718
1.56
10.54
3.8
3.3
521.0
287.9
mg/l
0.40
254
1757
306
2123
1.60
10.53
1.6
1.5
18.9
20.6
nmol/l
1.09
256
1809
979
8797
1.76
10.49
6.7
5.6
41.0
39.7
mmol/mol
3.24
881
8189
372
2704
1.56
10.46
4.6
4.1
7.4
7.4
ph
0.32
64
528
146
829
1.87
10.37
4.5
3.5
1.8
2.1
mmol/l
0.45
122
656
1120
10590
3.28
10.14
31.6
20.3
249.3
249.9
e9/l
0.13
1101
10328
222
1435
1.68
10.08
3.0
2.4
12.3
13.5
umol/l
1.77
200
1330
393
2914
1.53
10.00
3.7
3.2
7.6
7.8
mmol/l
0.27
334
2454
1120
10597
3.25
9.99
31.5
20.2
30.3
30.4
pg
0.89
1111
10444
1120
10597
3.25
9.99
31.5
20.2
91.0
91.0
fl
0.11
1111
10444
1120
10598
3.25
9.97
31.6
20.3
4.5
4.5
e12/l
1.64
1099
10311
1120
10599
3.25
9.94
31.7
20.3
7.0
6.7
e9/l
5.19
1099
10309
172
1042
1.77
9.86
6.2
8.6
0.8
1.2
mmol/l
0.66
130
816
1120
10603
3.23
9.86
31.8
20.4
134.5
136.3
g/l
3.62
1111
10447
321
2287
1.56
9.74
2.5
2.1
3.0
3.0
mg/l
0.01
279
1952
1071
9950
2.13
9.67
19.4
13.1
—
—
—
0
0
171
1045
1.75
9.50
6.3
8.5
11.7
12.2
kpa
0.76
160
1009
171
1045
1.75
9.50
6.3
8.5
5.1
5.1
kpa
0.43
159
1006
194
1228
1.70
9.50
3.1
2.4
21.6
23.9
%
1.49
164
1057
206
1326
1.67
9.47
3.0
2.4
2.3
2.3
g/l
0.29
186
1232
229
1515
1.64
9.46
4.1
3.4
0.8
0.8
mmol/l
0.98
214
1426
136
785
1.83
9.15
2.3
2.4
8.7
7.3
ug/l
0.29
123
706
462
3594
1.48
9.11
4.6
3.5
33.6
39.8
ng/l
0.53
328
2461
187
1189
1.68
8.98
7.6
5.7
1.1
1.0
mmol/l
1.00
178
1114
520
4149
1.46
8.96
12.1
9.3
0.0
0.0
e9/l
0.12
431
3425
16
28
5.78
8.82
1.1
1.7
—
—
—
0
0
345
2551
1.50
8.65
3.3
3.0
0.5
0.5
e6/l
0.16
270
1906
193
1249
1.66
8.64
1.4
1.3
817.8
488.1
titre
0.96
45
256
381
2877
1.49
8.61
4.2
4.0
9.5
8.8
mg/mmol
0.16
260
1836
135
798
1.78
8.38
9.1
7.6
11.0
9.6
mmol/l
1.27
129
760
1081
10154
2.09
8.24
13.9
10.2
28.5
26.9
u/l
1.85
1044
9817
152
936
1.72
8.18
6.6
9.0
95.9
95.7
%
0.25
146
906
178
1150
1.65
7.99
35.2
23.8
1.1
1.2
inr
1.35
17
160
133
795
1.76
7.95
6.5
7.5
1.4
1.3
mmol/l
0.39
126
767
73
360
2.10
7.76
4.6
4.7
—
—
—
0
0
417
3261
1.44
7.66
3.9
3.6
51.2
110.2
e6/l
1.32
296
2301
330
2476
1.47
7.52
3.3
3.0
—
—
—
0
0
331
2488
1.46
7.46
3.2
2.6
4625.5
6544.6
umol/l
0.31
287
2175
128
771
1.74
7.44
3.8
3.3
—
—
—
0
0
212
1454
1.56
7.40
2.8
2.9
2.5
2.2
e6/l
0.12
117
791
538
4426
1.41
7.33
4.2
4.0
—
—
—
0
0
350
2677
1.44
7.15
3.5
3.0
—
—
—
0
0
123
743
1.73
7.08
2.3
2.9
66.1
66.6
g/l
0.33
111
686
137
855
1.68
7.01
2.7
2.4
33.3
38.4
u/l
0.67
118
729
233
1651
1.52
6.98
3.2
3.1
2.5
2.4
mmol/l
1.61
200
1459
289
2140
1.47
6.97
5.2
4.4
—
—
—
0
0
342
2616
1.44
6.95
3.3
3.0
1697.6
1267.7
ng/l
1.06
294
2236
362
2806
1.42
6.81
2.3
2.1
159.2
231.2
u/l
1.43
347
2659
84
461
1.89
6.64
8.1
11.1
24.4
24.4
mmol/l
0.00
75
437
104
610
1.78
6.64
3.6
5.8
—
—
—
0
0
54
253
2.19
6.57
1.4
1.2
80.0
84.3
titre
—
5
21
120
738
1.70
6.48
3.2
2.9
246.0
198.8
ng/l
0.44
110
678
117
717
1.70
6.40
2.7
2.7
10.0
10.7
g/l
1.37
108
662
104
618
1.75
6.35
2.6
2.6
—
—
—
0
0
357
2798
1.40
6.20
3.5
3.1
198.1
84.0
e6/l
0.52
282
2142
243
1777
1.47
6.17
3.9
3.7
1157.1
414.4
ng/l
0.65
186
1361
889
8090
1.44
6.08
27.0
17.7
332.0
332.8
g/l
1.66
882
8034
545
4587
1.36
6.04
4.2
3.5
0.0
0.0
estimate
0.00
96
867
259
1928
1.44
5.98
2.7
2.5
7.4
5.4
e6/l
0.62
230
1699
993
9248
1.54
5.92
5.4
4.5
6.2
5.9
mmol/l
4.28
905
8457
262
1965
1.43
5.79
1.6
1.7
29302759.4
26399452.5
pmol/l
0.03
215
1644
133
865
1.61
5.78
2.8
2.2
357.7
368.6
nmol/l
0.31
125
801
27
97
2.83
5.76
1.9
1.6
—
—
—
0
0
155
1047
1.56
5.74
1.8
1.6
—
—
—
0
0
53
262
2.07
5.66
3.5
3.4
—
—
—
0
0
868
7908
1.40
5.54
24.2
16.8
13.8
13.6
%
2.97
861
7749
97
591
1.70
5.44
1.3
1.2
703.9
216.0
u/ml
1.56
89
550
541
4596
1.33
5.44
5.7
4.8
0.0
0.0
estimate
0.50
94
876
14
35
4.04
5.18
1.2
1.5
—
—
—
0
0
1024
9662
1.55
5.08
5.4
4.8
2.7
2.8
mmol/l
4.00
937
8930
69
390
1.82
5.02
1.9
2.0
6.1
1.9
ug/l
0.52
55
356
56
297
1.93
4.96
7.5
10.6
—
—
—
0
0
93
576
1.67
4.92
1.6
1.8
1.0
1.4
g/l
2.95
84
539
369
2997
1.34
4.92
2.9
2.6
65.4
57.7
u/l
0.45
348
2779
541
4641
1.31
4.90
4.2
3.6
0.0
0.0
estimate
0.80
92
843
42
203
2.11
4.80
2.0
2.5
—
—
—
0
0
973
9115
1.44
4.71
4.4
3.9
1.4
1.3
mmol/l
3.47
882
8399
64
362
1.81
4.66
5.7
3.8
24.9
24.9
mmol/l
0.02
58
342
93
587
1.64
4.59
6.3
8.0
24.0
24.5
mmol/l
0.61
87
550
104
678
1.59
4.50
4.8
3.9
110.4
84.7
ng/l
1.30
95
607
47
243
1.97
4.50
1.3
1.2
—
—
—
0
0
91
576
1.63
4.45
1.2
1.3
16.5
43.5
au/ml
—
5
27
236
1814
1.38
4.43
2.8
2.7
555.2
553.2
mosm/kgh2o
0.05
205
1557
101
657
1.59
4.42
1.5
1.4
—
—
—
0
0
935
8731
1.38
4.33
22.1
14.7
40.0
40.1
%
0.08
667
6336
17
57
3.01
4.13
1.1
1.0
—
—
—
0
0
1003
9497
1.44
4.12
4.9
4.4
4.5
4.7
mmol/l
6.83
922
8836
10
23
4.38
4.09
1.6
2.3
16.7
18.6
umol/l
—
10
23
70
424
1.69
4.06
5.6
3.5
—
—
—
0
0
150
1081
1.45
4.06
2.5
2.7
12.3
8.5
umol/l
0.42
129
943
470
4030
1.28
4.02
3.4
2.7
132.4
135.6
ug/l
0.10
428
3737
90
583
1.59
4.02
5.5
3.4
5.3
5.2
kpa
1.19
84
546
89
575
1.59
4.02
5.4
3.4
7.4
7.4
ph
0.61
12
75
231
1796
1.36
4.01
1.5
1.5
2.6
2.5
g/l
0.24
141
1137
66
396
1.71
3.97
1.9
2.1
1.7
1.5
g/l
0.45
56
345
735
6666
1.28
3.97
4.4
3.8
—
—
—
0
0
257
2041
1.33
3.87
1.4
1.2
2.4
1.7
u/ml
0.28
68
568
258
2055
1.33
3.80
5.0
3.9
1.0
1.0
kg/l
0.24
33
288
996
9447
1.41
3.78
4.8
4.3
1.4
1.5
mmol/l
13.02
914
8732
47
260
1.84
3.73
1.6
1.5
241.0
281.7
ug/g
0.61
28
155
205
1585
1.36
3.68
2.1
1.8
—
—
—
0
0
23
97
2.40
3.66
1.3
1.3
14350.9
104261.0
e6/l
0.76
14
72
434
3718
1.27
3.65
2.1
2.1
—
—
—
0
0
12
36
3.36
3.48
1.0
1.2
—
—
—
0
0
12
36
3.36
3.48
2.0
1.4
—
—
—
0
0
99
679
1.50
3.46
1.5
1.4
—
—
—
0
0
23
100
2.33
3.44
2.7
4.5
—
—
—
0
0
121
866
1.44
3.41
2.7
2.2
0.2
0.2
g/l
0.04
111
809
22
95
2.34
3.35
1.1
1.6
—
—
—
0
0
110
776
1.46
3.35
3.8
4.1
0.8
1.0
%
0.50
41
233
123
887
1.43
3.33
6.1
4.4
—
—
—
0
0
55
333
1.68
3.25
2.6
2.3
559.5
436.4
ug/l
0.17
50
315
104
732
1.46
3.21
3.6
4.2
0.1
0.1
%
0.24
37
210
8
15
5.36
3.19
1.5
1.1
—
—
—
0
0
136
1007
1.40
3.18
2.9
2.7
1.8
1.8
%
0.14
120
911
17
67
2.56
3.13
3.9
2.1
644.0
741.5
e6/l
—
7
27
100
703
1.46
3.11
3.4
4.0
1.0
0.4
%
1.31
33
166
306
2560
1.27
3.05
1.7
1.7
1.5
1.4
mmol/l
1.48
257
2142
49
293
1.70
3.05
1.3
1.2
—
—
—
0
0
139
1043
1.38
3.01
2.0
1.6
—
—
—
0
0
42
241
1.77
3.01
2.1
1.7
10210.1
15015.3
e6/l
0.58
30
181
47
279
1.71
3.00
1.7
2.5
38.1
37.7
g/l
0.22
40
246
21
94
2.26
2.97
2.0
1.5
—
—
—
0
0
319
2693
1.26
2.93
5.1
3.7
—
—
—
0
0
18
76
2.39
2.90
2.4
2.2
1.0
1.1
e9/l
—
8
43
17
70
2.45
2.88
3.5
2.2
—
—
—
0
0
20
89
2.27
2.88
2.9
3.9
60.5
53.2
%
0.71
15
66
97
689
1.45
2.88
3.7
4.2
0.0
0.6
%
0.66
33
177
169
1320
1.33
2.83
1.2
1.2
—
—
—
0
0
23
110
2.11
2.80
1.0
1.2
—
—
—
0
0
73
493
1.51
2.78
7.9
11.6
—
—
—
0
0
14
54
2.61
2.71
1.1
1.0
—
—
—
0
0
96
689
1.43
2.70
1.2
1.2
—
—
—
0
0
137
1047
1.35
2.66
1.4
1.3
—
—
—
0
0
36
210
1.74
2.49
4.9
3.4
42.3
35.6
umol/l
0.72
31
173
17
76
2.26
2.45
1.2
1.2
—
—
—
0
0
377
3300
1.21
2.40
4.6
4.8
3.0
2.4
ug/l
0.40
328
2967
66
455
1.48
2.32
2.6
2.4
—
—
—
0
0
310
3568
0.82
2.32
2.9
2.8
—
—
—
0
0
33
194
1.72
2.24
2.3
2.2
134.5
130.1
g/l
0.48
23
145
18
86
2.11
2.23
1.6
1.4
32.4
32.2
%
—
10
61
196
1614
1.26
2.20
1.3
1.3
19.3
37.4
iu/ml
2.52
49
494
26
143
1.84
2.20
5.1
2.1
—
—
—
0
0
163
1313
1.28
2.20
1.9
1.6
—
—
—
0
0
15
67
2.26
2.18
1.3
1.4
—
—
—
0
0
6
14
4.30
2.15
1.0
1.6
—
—
—
0
0
31
183
1.71
2.09
1.1
1.5
—
—
—
0
0
99
749
1.35
2.09
3.1
2.8
66.6
70.5
e9/l
0.68
78
589
289
2495
1.21
2.09
4.7
3.8
0.0
0.0
estimate
0.88
92
850
44
285
1.57
2.08
3.6
3.8
30.4
31.2
mg/l
0.05
39
236
39
246
1.61
2.06
3.8
1.8
—
—
—
0
0
45
294
1.55
2.06
3.6
1.9
—
—
—
0
0
7
20
3.51
2.05
1.3
1.1
—
—
—
0
0
13
56
2.34
2.05
1.5
2.0
16.8
15.7
%
—
8
25
57
395
1.47
1.99
1.2
1.2
—
—
—
0
0
148
1198
1.27
1.93
1.3
1.3
—
—
—
0
0
11
45
2.46
1.93
3.9
2.6
—
—
—
0
0
29
174
1.68
1.87
1.7
1.6
—
—
—
0
0
49
334
1.49
1.87
1.6
1.6
—
—
—
0
0
10
40
2.51
1.84
42.5
31.2
86.6
124.8
ug/l
—
10
30
47
321
1.48
1.79
3.7
1.8
—
—
—
0
0
23
131
1.77
1.78
1.5
1.4
0.3
0.3
nmol/l
0.00
16
101
27
162
1.68
1.76
1.2
1.3
52.6
62.2
mmol/l
0.73
20
138
10
41
2.45
1.75
1.1
9.3
—
—
—
0
0
16
81
1.99
1.75
1.6
1.3
6.6
6.9
g/l
—
9
56
16
81
1.99
1.75
1.6
1.3
0.5
0.3
g/l
—
9
56
16
81
1.99
1.75
1.6
1.3
3.5
2.7
g/l
—
10
54
44
298
1.50
1.75
1.3
1.2
—
—
—
0
0
182
1527
1.23
1.74
1.2
1.3
6.2
12.6
u/ml
1.10
61
605
47
323
1.47
1.74
3.5
1.8
—
—
—
0
0
30
187
1.62
1.70
1.2
1.2
192.0
263.5
u/ml
0.85
18
116
28
172
1.64
1.68
1.1
1.2
—
—
—
0
0
47
326
1.46
1.67
3.6
1.8
—
—
—
0
0
7
25
2.81
1.65
1.0
1.0
—
—
—
0
0
16
83
1.94
1.65
4.2
4.1
—
—
—
0
0
46
319
1.46
1.64
3.4
3.8
0.6
0.2
g/l
0.85
21
135
26
158
1.66
1.63
1.1
1.1
—
—
—
0
0
71
533
1.35
1.62
1.4
1.2
—
—
—
0
0
18
98
1.85
1.62
2.4
2.4
—
—
—
0
0
12
56
2.15
1.61
1.4
1.6
—
—
—
0
0
20
113
1.78
1.61
1.6
1.6
51.6
59.3
%
—
10
79
136
1116
1.25
1.61
3.0
2.3
131.4
127.7
ug/g
0.03
115
887
61
448
1.38
1.60
6.1
3.3
24.6
25.3
mmol/l
0.97
61
437
16
84
1.92
1.60
1.6
1.3
—
—
—
0
0
7
26
2.70
1.58
1.9
2.0
—
—
—
0
0
29
184
1.59
1.55
3.0
2.5
17.7
16.3
%
1.11
15
93
31
200
1.57
1.55
1.6
1.7
—
—
—
0
0
24
145
1.67
1.55
1.5
1.3
—
—
—
0
0
55
400
1.39
1.54
1.7
1.5
—
9.2
—
0
12
10
206
0.48
1.54
2.3
3.6
21.7
25.2
mg/l
—
5
128
46
325
1.43
1.51
3.6
1.8
—
—
—
0
0
20
116
1.74
1.49
1.1
1.3
—
0.5
—
0
13
43
302
1.44
1.46
1.7
1.5
342.1
289.3
mu/l
0.32
38
277
73
561
1.32
1.45
2.5
3.3
4.4
4.6
pmol/l
0.58
68
499
100
803
1.27
1.44
1.5
1.4
—
—
—
0
0
12
59
2.04
1.43
4.4
4.5
—
—
—
0
0
19
111
1.72
1.39
1.1
1.3
—
—
—
0
0
32
214
1.51
1.39
4.4
4.0
—
—
—
0
0
294
2632
1.16
1.36
1.4
1.4
—
—
—
0
0
24
152
1.59
1.32
2.0
1.5
—
—
—
0
0
31
211
1.48
1.26
3.6
2.3
—
—
—
0
0
30
203
1.49
1.25
1.2
1.3
—
—
—
0
0
22
139
1.59
1.23
1.8
1.6
0.8
0.8
g/l
0.04
15
106
15
85
1.77
1.23
1.0
1.1
—
—
—
0
0
18
108
1.68
1.22
1.1
1.1
—
—
—
0
0
28
191
1.48
1.14
1.7
1.4
—
—
—
0
0
40
293
1.38
1.13
2.3
1.7
40.0
39.7
nmol/l
0.02
35
283
113
949
1.21
1.12
1.7
1.4
—
—
—
0
0
7
31
2.27
1.10
1.1
1.1
—
—
—
0
0
13
74
1.77
1.07
1.2
1.1
—
—
—
0
0
11
60
1.84
1.03
1.7
1.7
—
—
—
0
0
5
23
2.18
0.98
1.0
1.1
—
—
—
0
0
7
37
1.90
0.94
1.0
1.1
—
—
—
0
0
18
117
1.55
0.94
1.1
1.3
0.6
0.6
nmol/l
0.06
18
111
23
159
1.46
0.91
1.0
1.2
—
—
—
0
0
6
29
2.07
0.89
6.5
4.6
—
—
—
0
0
6
29
2.07
0.89
2.2
2.7
—
—
—
0
0
25
177
1.42
0.89
1.4
1.4
75.8
106.6
u/ml
—
8
35
77
641
1.22
0.87
4.1
3.0
4.9
4.1
e9/l
1.08
54
516
16
103
1.56
0.87
1.1
1.3
—
—
nmol/l
—
0
0
16
103
1.56
0.87
2.9
2.6
—
—
—
0
0
20
137
1.47
0.84
4.5
2.7
10.5
35.6
u/ml
0.41
20
130
8
45
1.78
0.84
1.5
3.0
846.3
1439.8
u/ml
—
8
45
6
32
1.88
0.82
1.0
1.0
—
—
—
0
0
49
606
0.80
0.79
2.4
2.8
—
—
—
0
0
49
393
1.26
0.79
1.6
1.3
28.4
30.7
iu/l
0.17
41
338
8
48
1.67
0.79
1.1
1.9
—
—
—
0
0
213
1940
1.12
0.78
2.8
3.0
0.8
0.7
ug/l
0.06
139
1245
12
75
1.61
0.75
1.9
1.9
13.9
10.9
%
2.52
12
75
7
38
1.85
0.73
1.0
1.0
—
15.0
—
0
7
9
56
1.61
0.72
1.2
1.3
5.2
5.9
ug/l
—
9
45
13
84
1.55
0.72
1.2
1.3
481256.7
106224.0
e6/l
—
6
48
38
301
1.27
0.70
3.8
8.0
1.3
1.3
mmol/l
0.05
33
269
86
743
1.17
0.69
1.8
1.6
—
—
—
0
0
18
127
1.42
0.68
3.3
2.8
—
—
—
0
0
21
153
1.38
0.67
1.1
1.1
—
—
—
0
0
5
92
0.54
0.67
1.0
1.1
—
—
—
0
0
17
119
1.44
0.67
1.9
2.4
33.1
32.6
pg
0.25
17
119
22
162
1.37
0.66
5.0
2.6
—
—
—
0
0
5
95
0.52
0.66
1.6
1.2
—
—
—
0
0
59
495
1.20
0.66
1.5
1.7
—
—
—
0
0
7
44
1.59
0.65
1.3
1.2
—
—
—
0
0
31
242
1.29
0.64
4.7
3.8
7.4
7.4
ph
1.29
26
199
5
29
1.73
0.64
1.0
1.1
—
—
—
0
0
87
759
1.16
0.63
2.7
2.2
11.1
13.2
nmol/l
1.64
74
685
22
164
1.35
0.62
4.8
2.6
—
—
—
0
0
13
89
1.47
0.58
1.7
1.5
—
—
—
0
0
26
202
1.29
0.57
5.2
4.1
2.5
2.5
mmol/l
0.00
20
139
27
212
1.28
0.56
1.2
1.4
2.9
48.4
e6/l
0.96
22
166
25
195
1.29
0.54
3.5
3.3
—
—
—
0
0
13
91
1.43
0.53
1.2
1.2
—
—
—
0
0
6
40
1.50
0.51
1.2
2.2
16.6
228.6
ug/l
—
6
33
19
144
1.32
0.50
1.6
1.7
—
—
—
0
0
86
768
1.13
0.48
6.5
3.6
1.2
1.2
mmol/l
0.12
78
669
33
272
1.22
0.47
2.8
2.1
18700.1
2738.2
u/l
—
9
114
12
85
1.42
0.47
2.4
2.2
—
2.1
—
0
6
34
285
1.20
0.43
1.1
1.3
364.7
229.0
miu/ml
0.85
12
133
12
87
1.38
0.42
1.2
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
6.7
—
0
16
53
603
0.87
0.41
1.5
1.4
—
—
—
0
0
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
50
437
1.15
0.40
1.1
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
13
97
1.34
0.39
1.2
1.2
—
—
—
0
0
7
104
0.67
0.39
1.1
1.7
—
—
—
0
0
14
106
1.32
0.39
1.1
1.2
—
—
—
0
0
43
374
1.16
0.37
3.1
2.6
—
—
—
0
0
14
107
1.31
0.37
1.0
1.2
—
—
—
0
0
20
161
1.25
0.37
1.1
1.1
—
—
—
0
0
23
189
1.22
0.36
3.3
3.8
57.0
56.5
%
0.09
23
189
22
182
1.21
0.33
3.1
3.4
3.9
4.2
e9/l
0.47
22
182
6
46
1.31
0.33
1.0
1.3
—
—
—
0
0
17
208
0.81
0.31
1.9
2.0
—
—
—
0
0
7
52
1.35
0.31
1.7
1.3
134.0
151.3
nmol/l
—
7
52
10
76
1.32
0.28
1.3
1.3
—
—
—
0
0
65
595
1.10
0.27
1.4
1.2
—
—
—
0
0
8
66
1.21
0.26
1.3
1.1
—
—
—
0
0
13
104
1.25
0.26
3.1
2.4
—
—
—
0
0
19
160
1.19
0.25
1.1
1.1
—
—
—
0
0
18
212
0.85
0.24
1.3
1.3
—
—
—
0
0
17
143
1.19
0.23
1.2
1.2
—
—
—
0
0
42
463
0.90
0.23
5.2
3.6
—
—
—
0
0
5
40
1.25
0.22
1.2
1.1
2797.8
1576.6
miu/ml
—
5
40
68
632
1.08
0.22
1.3
1.2
140.9
138.7
iu/ml
0.02
24
270
85
798
1.07
0.22
4.3
3.5
—
—
—
0
0
38
419
0.90
0.21
1.7
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
4.1
—
—
—
0
0
14
117
1.20
0.20
1.5
1.6
—
—
—
0
0
14
117
1.20
0.20
1.5
1.6
—
—
—
0
0
14
117
1.20
0.20
1.5
1.6
—
—
—
0
0
14
117
1.20
0.20
1.5
1.6
—
—
—
0
0
6
48
1.25
0.20
1.3
1.3
180.2
567.5
u/l
—
6
43
92
970
0.94
0.19
1.3
1.3
—
—
—
0
0
28
253
1.11
0.17
1.1
1.1
—
—
—
0
0
8
71
1.13
0.16
1.9
1.3
—
—
—
0
0
99
948
1.05
0.15
3.3
4.4
6.0
27.8
ug/l
1.58
74
792
15
132
1.14
0.13
1.1
1.0
1.3
2.9
u/ml
—
5
36
15
133
1.13
0.12
1.2
1.2
—
—
—
0
0
12
137
0.87
0.12
1.1
1.0
1.2
0.9
u/ml
—
7
51
11
124
0.89
0.09
1.1
1.0
17.0
3.2
u/ml
—
5
45
5
61
0.82
0.08
2.0
2.1
434.2
491.8
min
—
5
41
16
146
1.10
0.08
1.4
1.5
—
—
—
0
0
5
65
0.77
0.08
1.2
1.0
—
—
—
0
0
11
123
0.89
0.08
3.1
2.5
4.1
4.0
mmol/l
0.21
11
123
11
123
0.89
0.08
3.1
2.5
105.5
105.6
mmol/l
0.01
11
123
84
864
0.97
0.07
1.5
1.4
—
—
—
0
0
8
77
1.04
0.07
2.1
1.4
0.9
1.0
g/l
—
8
77
19
204
0.93
0.07
1.6
1.6
—
—
—
0
0
18
167
1.08
0.07
1.1
1.4
—
—
—
0
0
9
103
0.87
0.06
1.9
1.8
—
—
—
0
0
11
121
0.91
0.06
3.1
2.5
—
—
—
0
0
19
202
0.94
0.05
1.1
1.2
—
—
—
0
0
12
110
1.09
0.05
1.1
1.1
21.5
3.8
u/ml
—
6
43
15
140
1.07
0.04
1.4
1.4
—
—
—
0
0
15
140
1.07
0.04
1.4
1.4
—
—
—
0
0
12
129
0.93
0.03
2.6
2.6
—
—
—
0
0
16
151
1.06
0.03
1.1
1.1
—
13.5
—
0
9
253
2543
0.99
0.02
3.7
3.2
—
—
—
0
0
16
153
1.05
0.01
1.1
1.2
1.6
6.9
u/ml
—
10
62
25
243
1.03
0.01
2.8
2.4
134.0
100.9
ug/min
0.23
17
148
23
236
0.97
0.00
1.7
1.8
5.4
5.0
iu/l
—
7
81
24
246
0.98
0.00
7.0
4.7
—
—
—
0
0
14
144
0.97
0.00
1.1
1.0
6.1
6.3
u/ml
—
9
67
15
148
1.01
0.00
1.3
1.2
—
—
—
0
0
16
159
1.01
0.00
1.3
1.1
7.0
2.0
u/ml
—
9
61
35
349
1.00
0.00
1.1
1.1
—
—
—
0
0
11
105
1.05
0.00
1.8
1.3
—
—
—
0
0
9
97
0.93
0.00
2.0
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
1.4
2.6
2084.0
2067.3
ml
—
5
47
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.9
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
7.8
—
0
5
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
100.0
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.0
—
181.3
—
0
7
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
54
0.93
0.00
1.4
1.5
—
10.7
—
0
5
9
96
0.94
0.00
2.3
2.4
—
—
—
0
0
0
7
0.00
0.00
0.0
3.4
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
33.3
—
0
5

Mortality – FinRegistry

Association

Association between endpoint H8_EXTDISINOTH and mortality.

Females

Parameter HR [95% CI] p-value
H8_EXTDISINOTH 1.404 [1.19, 1.66] < 0.001
Birth year 0.998 [0.99, 1.01] 0.619

During the follow-up period (1.1.1998 — 31.12.2019), 419 out of 2954 females with H8_EXTDISINOTH died.

Males

Parameter HR [95% CI] p-value
H8_EXTDISINOTH 1.515 [1.27, 1.8] < 0.001
Birth year 0.987 [0.98, 1.0] 0.007

During the follow-up period (1.1.1998 — 31.12.2019), 517 out of 3092 males with H8_EXTDISINOTH died.

Mortality risk

Mortality risk for people of age

years, who have H8_EXTDISINOTH.

N-year risk Females Males
1 0.167% 0.355%
5 0.973% 1.728%
10 2.414% 4.346%
15 4.32% 8.045%
20 7.788% 13.438%

Relationships between endpoints

Index endpoint: H8_EXTDISINOTH – Disorder of external ear, unspecified

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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