Chronic postrheumatic arthropathy [Jaccoud]

M13_POSTRHEU

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M12.0 Hospital discharge: ICD-8 — 7125 Cause of death: ICD-10 — M12.0 Cause of death: ICD-8 — 7125 2 out of 7 registries used, show all original rules.	51
4. Check minimum number of events None	51
5. Include endpoints None	51
6. Filter based on genotype QC (FinnGen only)	49

Control definitions (FinnGen only)

Control exclude: M13_ARTHROPATHIES

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M12
Name in latin: Arthropathia postrheumatica chronica (Jaccoud)

NAME	M13_POSTRHEU
CONTROL_EXCLUDE	M13_ARTHROPATHIES
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M120
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	7125
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M120
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	7125
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Chronic postrheumatic arthropathy [Jaccoud] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	427	288	134
Only index persons	340	231	109
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	57.18	57.81	55.83
Only index persons	56.18	56.77	54.92

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	49	30	19
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	56.09	53.09	60.82

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
51: Matched controls
510

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M12.0

ICD-10 Finland

Chronic postrheumatic arthropathy [Jaccoud]

+∞

55.9

M17.1

ICD-10 Finland

Other primary gonarthrosis

80.9

21.4

M17.0

ICD-10 Finland

Primary gonarthrosis, bilateral

53.4

19.0

NGB20

NOMESCO Finland

Primary total prosthetic replacement of knee joint without patellar part

+∞

16.5

M25.5

ICD-10 Finland

Pain in joint

9.4

14.2

M01AH05

ATC

etoricoxib; oral

9.4

11.6

155

NGF25

NOMESCO Finland

Operation for osteochondritis of knee, arthroscopic

56.6

11.5

202

Kela drug reimbursment

Connective tissue diseases, rheumatoid arthritis and comparable disease

37.6

11.4

M19.0

ICD-10 Finland

Primary arthrosis of other joints

38.2

9.9

M05.8

ICD-10 Finland

Other seropositive rheumatoid arthritis

+∞

9.7

M09AX01

ATC

hyaluronic acid; parenteral

34.2

8.9

M23.2

ICD-10 Finland

Derangement of meniscus due to old tear or injury

+∞

8.6

71250

ICD-8 Finland

Rheumatoid arthritis and allied conditions, Chronic rheumatoid nodular fibrositis

+∞

7.5

L04AX03

ATC

methotrexate; systemic

35.6

7.4

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

4.9

7.3

102

NG1AA

NOMESCO Finland

Knee X-ray examination without contrast

17.0

7.3

L15

ICPC

Knee symptom/complaint

5.5

7.2

B01AB05

ATC

enoxaparin; parenteral

5.0

7.2

M79.6

ICD-10 Finland

Pain in limb

4.6

6.8

107

ZXE10

NOMESCO Finland

More than one and less than three hours

4.4

6.4

104

M22.0

ICD-10 Finland

Recurrent dislocation of patella

+∞

6.4

NGB40

NOMESCO Finland

Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis

+∞

6.4

NJ2MA

NOMESCO Finland

Measurement of mechanical axis of lower leg with X-ray

+∞

6.4

M01AC06

ATC

meloxicam; systemic, rectal

4.3

6.2

N02AJ06

ATC

codeine and paracetamol; systemic

4.3

6.2

M75.4

ICD-10 Finland

Impingement syndrome of shoulder

13.4

6.1

N02AX02

ATC

tramadol; systemic, rectal

4.2

6.1

114

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

5.72

7.21

1.3

1.2

35.88

14.76

iu/ml

—

(40760892) CBC W Ordered Manual Differential panel - Blood

148

2.54

2.68

10.0

5.0

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

3.54

2.36

5.0

2.6

—

59.60

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

4.38

2.10

1.5

1.0

—

(3012516) Albumin [Mass/volume] in Urine

101

2.21

1.79

2.9

3.0

2818.87

793.19

mg/l

0.30

(3045414) Leukocytes [Presence] in Urine

4.14

1.76

3.2

1.8

—

(3022217) INR in Platelet poor plasma by Coagulation assay

181

2.04

1.68

10.9

11.3

0.99

1.30

inr

—

(3026493) Urate [Moles/volume] in Serum or Plasma

2.23

1.58

5.3

2.7

348.00

25211.33

umol/l

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.57

1.56

1.4

2.5

—

(3042936) Bacteria identified in Isolate by Culture

2.45

1.46

2.0

1.4

—

(4200892) Spirometry reversibility

2.32

1.39

1.6

1.4

—

(3020682) Albumin/Creatinine [Ratio] in Urine

111

1.96

1.36

3.8

1.01

10.83

mg/mmol

1.61

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.96

1.31

1.6

1.8

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

392

2.25

1.12

15.4

12.7

18.86

25.23

mg/l

0.64

292

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.16

1.04

2.4

1.5

—

(40761535) Cells panel - Urine sediment

2.16

1.04

3.4

3.6

—

(3000991) Gas panel - Venous blood

0.00

0.99

0.0

7.5

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

151

1.66

0.92

2.9

3.5

17.27

58.64

ng/l

0.89

113

(3007853) Bacteria identified in Skin by Aerobe culture

2.13

0.90

1.5

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.92

0.89

1.5

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.81

0.87

3.6

4.6

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.79

0.83

4.4

6.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

271

1.62

0.82

6.2

4.0

—

(3000330) Specific gravity of Urine by Test strip

2.11

0.75

5.0

4.2

—

(3013512) EKG study

114

1.59

0.70

4.5

4.1

—

(3003694) ABO and Rh group [Type] in Blood

110

0.58

0.68

1.4

1.3

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

0.00

0.61

0.0

4.3

—

24.06

—

(40758558) Short blood count panel - Blood

1.58

0.60

9.5

5.9

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

1.81

0.60

7.3

3.2

235.50

225.09

u/l

—

(3014007) Fractional oxyhemoglobin in Arterial blood

0.00

0.60

0.0

8.2

—

93.80

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.60

0.0

1.5

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.55

0.57

1.7

1.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

166

1.45

0.56

2.4

2.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

224

1.44

0.56

3.3

3.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

149

1.44

0.52

3.7

3.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.60

0.51

1.6

1.7

—

(40761511) CBC panel - Blood by Automated count

419

1.63

0.48

15.9

12.9

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.46

0.47

1.4

2.1

2.25

2.38

g/l

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

181

1.38

0.45

4.6

5.8

1.20

1.22

mmol/l

0.50

167

(3018095) Leukocytes [#/volume] in Urine

143

1.40

0.45

4.0

3.7

2.52

62.94

e6/l

2.17

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.42

0.43

1.9

1.3

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.47

0.42

1.7

1.6

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

0.00

0.42

0.0

10.2

—

23.74

—

(3023421) Hepatitis B virus surface Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

305.56

—

(3020891) Body temperature

0.00

0.41

0.0

3.6

—

(3002385) Erythrocyte distribution width [Ratio]

345

1.40

0.40

17.0

16.1

16.45

14.82

0.66

335

(1761868) Lipid panel - Serum or Plasma

128

1.36

0.38

2.8

3.5

—

(40761536) Microorganisms panel - Urine sediment

1.48

0.37

4.2

3.4

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

158

1.32

0.35

2.7

1.9

96.80

92.31

pmol/l

0.14

(3020564) Creatinine [Moles/volume] in Serum or Plasma

415

1.44

0.35

17.9

15.2

76.95

77.99

umol/l

0.10

415

(40768804) Tissue Pathology biopsy report

169

1.30

0.33

2.1

2.2

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.29

0.31

2.6

1.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

0.72

0.26

1.5

1.9

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.24

0.22

3.0

3.3

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.21

0.0

1.8

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.2

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.21

0.0

1.4

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.5

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.2

—

(3024928) Oxygen saturation in Venous blood

0.00

0.21

0.0

2.0

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.21

0.0

1.6

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.21

0.0

3.7

—

(3036489) Thrombin time

0.00

0.21

0.0

1.2

—

20.90

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.3

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.21

0.0

1.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.3

—

(40768797) Stomach Pathology biopsy report

1.28

0.21

1.0

1.1

—

(3027008) Opiates [Presence] in Urine

0.00

0.21

0.0

1.3

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.21

0.0

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3016879) Cocaine [Presence] in Urine

0.00

0.21

0.0

1.3

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.21

0.0

1.3

—

(3044889) 12 lead EKG panel

266

1.21

0.21

5.7

3.7

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.20

0.0

1.1

—

(40758310) Human epididymis protein 4 [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.2

—

797.10

—

(40768793) Breast Pathology biopsy report

0.00

0.20

0.0

1.4

—

(1002224) Polysomnography panel

0.00

0.20

0.0

1.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.20

0.0

1.8

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.13

0.16

1.8

3.2

2.44

2.47

mmol/l

—

(3041096) Erythrocytes [Presence] in Urine by Automated

114

1.19

0.13

3.6

3.2

—

(3022145) Colonoscopy Study observation

1.12

0.10

1.6

1.2

—

(3044640) Blood type and Crossmatch panel - Blood

107

1.16

0.09

1.7

2.1

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

0.80

0.09

3.8

2.5

0.68

1.44

e6/l

—

(3007461) Platelets [#/volume] in Blood

441

1.17

0.08

23.3

18.4

252.36

249.27

e9/l

0.12

425

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.10

0.08

2.4

1.6

—

(3023368) Bacteria identified in Blood by Culture

1.14

0.07

4.2

3.6

—

(3026008) Bacteria identified in Urine by Culture

122

1.09

0.03

6.2

3.1

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

144

1.06

0.01

2.8

3.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

369

1.01

0.00

13.6

12.6

77.28

79.09

ml/min/173m2

0.23

306

(36304419) Bacteria [Presence] in Urine

108

1.02

0.00

4.2

2.8

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3003181) Sodium [Moles/volume] in Urine

0.00

-0.00

0.0

1.4

—

47.25

—

(3024731) MCV [Entitic volume]

442

1.15

-0.00

23.2

18.4

91.78

90.95

0.55

432

(3026361) Erythrocytes [#/volume] in Blood

442

1.15

-0.00

23.3

18.4

4.39

4.42

e12/l

0.17

427

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

1.7

—

(3009542) Hematocrit [Volume Fraction] of Blood

442

1.15

-0.00

23.0

18.4

39.82

39.28

0.19

405

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.8

—

28.12

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.5

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

-0.00

0.0

1.2

—

79.50

—

(3044290) Cell count panel - Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.0

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

3.60

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.2

—

(44816559) Phosphatidylethanol [Mass/volume] in Blood

0.00

-0.00

0.0

1.4

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

1.0

—

12.67

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.2

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

-0.00

0.0

1.8

—

(3019250) Coagulation factor VIII activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.1

—

175.57

—

(3007566) Smooth muscle Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3007798) IgG/Albumin [Mass Ratio] in Cerebral spinal fluid

0.00

-0.00

0.0

1.6

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

2.1

—

65.88

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

2.2

—

(3000012) Reticulocyte production index

0.00

-0.00

0.0

2.6

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

328.20

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3019897) Erythrocyte distribution width [Ratio] by Automated count

0.00

-0.00

0.0

1.0

—

13.00

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

2.3

—

29.83

—

(3034770) Mitochondria Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3036782) Glucose [Moles/volume] in Pleural fluid

0.00

-0.00

0.0

1.2

—

7.72

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3023183) Ammonium ion [Moles/volume] in Plasma

0.00

-0.00

0.0

1.8

—

26.13

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.2

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

3.5

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.2

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

8.4

—

26.86

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

5.0

—

3.20

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

(3011985) Renin [Units/volume] in Plasma

0.00

-0.00

0.0

1.0

—

25.70

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.6

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3003434) Protein [Mass/volume] in Pleural fluid

0.00

-0.00

0.0

1.3

—

33.68

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

1.8

—

(3000963) Hemoglobin [Mass/volume] in Blood

442

1.15

-0.00

23.5

18.5

133.18

133.23

g/l

0.01

431

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.0

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(3010813) Leukocytes [#/volume] in Blood

443

1.13

-0.00

23.3

18.3

7.29

6.71

e9/l

0.73

428

(3035941) MCH [Entitic mass]

442

1.15

-0.00

23.2

18.3

30.46

30.28

0.26

432

Mortality – FinRegistry

↥

Association

Association between endpoint M13_POSTRHEU and mortality.

Females

Parameter	HR [95% CI]	p-value
M13_POSTRHEU	1.159 [0.87, 1.54]	0.311
Birth year	0.989 [0.98, 1.0]	0.013

During the follow-up period (1.1.1998 — 31.12.2019), 52 out of 185 females with M13_POSTRHEU died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_POSTRHEU.

N-year risk	Females	Males
1	0.088%	No data
5	0.514%	No data
10	1.368%	No data
15	2.583%	No data
20	4.369%	No data

Relationships between endpoints

↥

Index endpoint: M13_POSTRHEU – Chronic postrheumatic arthropathy [Jaccoud]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Chronic postrheumatic arthropathy [Jaccoud]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints