Allergic purpura

D3_ALLERGPURPURA

Henoch-Schoenlein purpura: A systemic, usually self-limited immune complex vasculitis, characterized by immunoglobulin A deposition in the small vessels and kidneys. It is manifested with small hemorrhages in the skin, gastrointestinal symptoms, arthritis, and nephropathy.

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Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D69.0
  • Hospital discharge: ICD-9 2870
  • Hospital discharge: ICD-8 2870
  • Cause of death: ICD-10 D69.0
  • Cause of death: ICD-9 2870
  • Cause of death: ICD-8 2870

2 out of 7 registries used, show all original rules.

1213

4. Check minimum number of events

None

1213

5. Include endpoints

None

1213

6. Filter based on genotype QC (FinnGen only)

1168

Control definitions (FinnGen only)

Control exclude
D3_COAGDEF_PURPUR_HAEMORRHAGIC

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D69
Name in latin
Purpura allergica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11658 5675 5938
Only index persons 10225 5070 5155
Unadjusted period prevalence (%)
Whole population 0.16 0.16 0.17
Only index persons 0.19 0.19 0.20
Median age at first event (years)
Whole population 19.15 23.45 14.73
Only index persons 18.96 23.33 14.66

-FinnGen-

Key figures

All Female Male
Number of individuals 1168 685 483
Unadjusted period prevalence (%) 0.23 0.24 0.22
Median age at first event (years) 40.32 35.53 47.13

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1213
Matched controls
12130
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D69.0
ICD-10 Finland
Allergic purpura
8605.0
307.7
898
*
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
121.2
255.9
130
12
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
7.6
181.2
302
507
28700
ICD-8 Finland
Purpura and other haemorrhagic conditions, Allergic purpura
+∞
174.3
163
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
41.9
153.4
93
24
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
144.7
136
*
2870A
ICD-9 Finland
Purpura and other haemorrhagic conditions, Allergic purpura[PURPURA HENOCH-SCHÖNLEIN]
+∞
103.7
98
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
15.6
80.7
71
48
H02AB06
ATC
prednisolone; systemic
3.0
74.2
716
3962
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
105.1
55.3
60
6
J04BA02
ATC
dapsone; oral
22.3
55.3
41
19
L95.8
ICD-10 Finland
Other vasculitis limited to skin
70.0
52.7
60
9
M36.4*D69.0
ICD-10 Finland
Arthropathy in Henoch(-Schönlein) purpura
+∞
51.4
49
*
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
135.7
49.2
52
*
L04AX01
ATC
azathioprine; systemic
5.0
46.6
106
229
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
68.2
40.3
46
7
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.3
36.4
407
2216
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
35.3
207
836
D07AC01
ATC
betamethasone; topical
2.1
34.3
481
2853
L04AA01
ATC
[U] ciclosporin
10.0
34.0
39
40
N18.8
ICD-10 Finland
Other chronic renal failure
7.1
32.4
49
71
C03CA01
ATC
furosemide; systemic
2.2
31.2
338
1800
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
4.0
30.5
89
233
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
31.8
30.5
40
13
D69
ICD-10 Finland
Purpura and other haemorrhagic conditions
82.2
28.9
32
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
5.7
28.9
55
101
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
28.8
539
3493
L04AA06
ATC
mycophenolic acid; systemic
6.1
27.5
48
81
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
8.1
27.4
37
47
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
46.9
26.6
32
7
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.8
26.3
49
88
H02AB07
ATC
prednisone; oral
2.5
25.9
189
843
R23.3
ICD-10 Finland
Spontaneous ecchymoses
5.7
25.5
48
87
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
5.6
25.2
48
88
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
25.0
164
695
Z49.1
ICD-10 Finland
Extracorporeal dialysis
7.7
24.3
34
45
Z94.0
ICD-10 Finland
Kidney transplant status
7.5
24.3
35
48
E0000UV, ,
ATC
1.9
24.0
531
3573
TK800
NOMESCO Finland
Hemodialysis
5.7
23.8
45
82
A46
ICD-10 Finland
Erysipelas
2.4
23.7
182
828
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
244.6
23.7
24
*
127
Kela drug reimbursment
Transplant complication
6.1
23.0
40
67
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.5
22.6
81
244
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.6
22.5
141
583
H02AB04
ATC
methylprednisolone; systemic
2.3
22.2
191
913
A12AA04
ATC
calcium carbonate; oral
6.5
21.9
36
57
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.0
21.6
268
1477
L04AD01
ATC
ciclosporin; systemic
5.5
21.5
42
79
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
3.1
21.3
94
322
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.2
21.3
87
285
L95.0
ICD-10 Finland
Livedoid vasculitis
112.0
20.6
22
*
M31.9
ICD-10 Finland
Necrotizing vasculopathy, unspecified
112.0
20.6
22
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
20.5
147
647
A02BC02
ATC
pantoprazole; systemic
1.8
20.2
773
6009
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
3.3
20.0
77
243
L81.7
ICD-10 Finland
Pigmented purpuric dermatosis
29.5
19.7
26
9
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.2
19.2
188
945
TQW80
NOMESCO Finland
Local dermatologic skincare
4.3
19.0
49
117
D07AB08
ATC
desonide; topical
2.3
18.6
152
708
A11CC03
ATC
alfacalcidol; systemic
4.5
18.1
45
104
M04AA01
ATC
allopurinol; systemic
2.3
16.8
136
631
N02AX02
ATC
tramadol; systemic, rectal
1.7
16.4
474
3345
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.7
16.0
51
142
V03AE01
ATC
polystyrene sulfonate; oral
6.5
15.9
26
41
R31
ICD-10 Finland
Unspecified haematuria
2.4
15.8
120
540
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
15.6
314
2002
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.8
15.5
78
288
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
6.9
14.9
23
34
137
Kela drug reimbursment
Uraemia requiring dialysis
6.9
14.9
23
34
E000006, ,
ATC
2.5
14.9
93
383
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
14.7
246
1480
E000001, ,
ATC
1.8
14.7
251
1520
TPH04
NOMESCO Finland
Cathetrisation of vein
1.8
14.6
247
1492
D07AC13
ATC
mometasone; topical
1.7
14.6
336
2219
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
14.4
50
148
J01MA12
ATC
levofloxacin; systemic
1.9
14.3
203
1158
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.9
14.0
67
240
A02BC01
ATC
omeprazole; systemic
1.7
13.9
297
1918
205
Kela drug reimbursment
Chronic hypertension
1.8
13.9
245
1497
D09AB01
ATC
zinc bandage without supplements; topical
4.9
13.8
30
62
R50.9
ICD-10 Finland
Fever, unspecified
1.9
13.8
190
1074
ZX120
NOMESCO Finland
Intravenous
2.2
13.5
116
550
R80
ICD-10 Finland
Isolated proteinuria
10.2
13.0
25
25
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
12.7
434
3145
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
5.0
12.7
27
55
D07AD01
ATC
clobetasol; topical
1.9
12.6
183
1050
M10.9
ICD-10 Finland
Gout, unspecified
2.6
12.6
72
284
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.8
12.4
64
239
L04AX03
ATC
methotrexate; systemic
2.1
12.3
120
598
J01MA02
ATC
ciprofloxacin; systemic
1.6
12.1
404
2903
B03XA02
ATC
darbepoetin alfa; parenteral
4.1
11.9
32
79
L04AD02
ATC
tacrolimus; systemic
5.3
11.6
23
44
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
3.9
11.4
33
86
J01FF01
ATC
clindamycin; systemic
1.6
11.3
301
2043
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.3
11.2
88
402
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
4.8
11.2
25
53
R06AE07
ATC
cetirizine; oral
1.5
11.2
515
3959
QDA99
NOMESCO Finland
Other local destruction of skin of lower limb
25.3
11.1
15
6
B01AA03
ATC
warfarin; systemic
1.8
11.1
172
1006
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
8.7
11.0
23
27
N18.0
ICD-10 Finland
End-stage renal disease
5.8
11.0
20
35
C08CA01
ATC
amlodipine; oral
1.6
11.0
355
2522
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.9
11.0
32
84
M30.0
ICD-10 Finland
Polyarteritis nodosa
43.7
10.9
13
*
Z3231
NOMESCO Finland
Registered nurse
1.6
10.9
309
2128
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
28.3
10.7
14
5
L01BA01
ATC
methotrexate; systemic
3.0
10.6
47
162
M05BA04
ATC
alendronic acid; oral
2.2
10.6
86
399
M36.4
ICD-10 Finland
Arthropathy in hypersensitivity reactions classified elsewhere
+∞
10.4
10
*
C02AC05
ATC
moxonidine; oral
2.8
10.4
52
192
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
10.3
282
1925
J01DB01
ATC
cefalexin; oral
1.6
10.2
971
8631
J01FA06
ATC
roxithromycin; oral
1.5
10.1
430
3232
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.9
10.1
48
172
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.0
10.1
108
558
P01BA02
ATC
hydroxychloroquine; oral
2.1
10.1
94
461
C09AA02
ATC
enalapril; systemic
1.8
10.0
179
1090
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
10.0
105
538
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
10.0
98
490
C03DA01
ATC
spironolactone; oral
2.0
10.0
119
639
B03XA01
ATC
erythropoietin; parenteral
7.7
9.9
22
29
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.9
295
2052
D07AA02
ATC
hydrocortisone; topical
1.7
9.9
177
1080
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
9.8
180
1105
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
8.8
9.8
20
23
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
9.7
245
1634
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.4
9.7
69
302
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.9
9.7
136
771
J01AA02
ATC
doxycycline; systemic
1.5
9.6
840
7263
R06AX27
ATC
desloratadine; oral
1.5
9.6
351
2551
R60.0
ICD-10 Finland
Localized oedema
1.9
9.5
122
670
D68.0
ICD-10 Finland
Von Willebrand disease
100.8
9.4
10
*
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
17.7
9.4
14
8
M13.9
ICD-10 Finland
Arthritis, unspecified
2.1
9.2
88
435
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
9.2
246
1662
46100
ICD-8 Finland
Acute sinusitis, Maxillaris
3.5
9.2
31
90
J01CA04
ATC
amoxicillin; systemic
1.6
9.2
977
8761
D68.8
ICD-10 Finland
Other specified coagulation defects
13.8
9.2
15
11
XW000
NOMESCO Finland
Bone marrow biopsy
2.9
9.0
42
149
M31.8
ICD-10 Finland
Other specified necrotizing vasculopathies
37.0
9.0
11
*
Z3226
NOMESCO Finland
Physiotherapist
1.7
9.0
203
1316
B99
ICD-10 Finland
Other and unspecified infectious diseases
3.5
9.0
30
87
Z2221
NOMESCO Finland
Medical doctor
1.5
8.9
308
2206
J45.9
ICD-10 Finland
Asthma, unspecified
1.6
8.9
206
1345
V03AE02
ATC
sevelamer; oral
10.8
8.8
16
15
J01DA01
ATC
[U] cefalexin
1.4
8.7
683
5728
M30.8
ICD-10 Finland
Other conditions related to polyarteritis nodosa
50.4
8.7
10
*
D68.9
ICD-10 Finland
Coagulation defect, unspecified
50.4
8.7
10
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.5
163
1010
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
8.5
123
703
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
6.5
8.5
21
33
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.9
8.4
24
62
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.5
8.4
20
45
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
+∞
8.3
8
*
S97
ICPC
Chronic ulcer skin
2.3
8.3
64
291
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
8.3
608
5022
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
8.2
81
406
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
11.8
8.1
14
12
WX002
NOMESCO Finland
Sedation and analgesia
1.6
8.0
192
1261
E000002, ,
ATC
1.8
8.0
132
785
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
8.0
64
296
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
7.9
81
412
H02AB09
ATC
hydrocortisone; systemic
3.1
7.9
32
105
M25.5
ICD-10 Finland
Pain in joint
1.5
7.9
349
2621
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
7.9
102
563
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.1
7.9
20
33
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.8
152
948
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.4
7.7
52
223
XF400
NOMESCO Finland
ECG with 12 standard connections
1.7
7.7
156
982
SPAT1172
SPAT
Guidance concerning hydration
3.5
7.7
26
76
L03.9
ICD-10 Finland
Cellulitis, unspecified
3.3
7.7
28
86
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.9
7.7
97
531
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.7
269
1927
212
Kela drug reimbursment
Gout
4.0
7.6
21
53
M30.1
ICD-10 Finland
Polyarteritis with lung involvement [Churg-Strauss]
18.5
7.6
11
6
R60.9
ICD-10 Finland
Oedema, unspecified
2.3
7.6
56
250
L04AA13
ATC
[U] leflunomide
3.1
7.6
30
97
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
7.5
317
2358
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.6
7.4
41
160
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
7.4
537
4396
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
7.4
88
473
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
7.3
386
2986
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
7.3
133
813
JN4AD
NOMESCO Finland
Body CT examination
1.9
7.3
91
496
2870X
ICD-9 Finland
Purpura and other haemorrhagic conditions, Allergic purpura[PURPURA ALLERGICA NUD]
+∞
7.3
7
*
D69.1
ICD-10 Finland
Qualitative platelet defects
+∞
7.3
7
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
9.4
7.3
14
15
A07AA02
ATC
nystatin; oral
2.2
7.3
58
268
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.9
7.3
33
116
Z49.0
ICD-10 Finland
Preparatory care for dialysis
5.8
7.2
19
33
UJF32
NOMESCO Finland
Coloscopy
1.5
7.2
242
1715
J46
ICD-10 Finland
Status asthmaticus
2.8
7.2
35
128
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
7.2
109
633
C09CA01
ATC
losartan; oral
1.5
7.1
229
1607
Z49.2
ICD-10 Finland
Other dialysis
6.6
7.1
17
26
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.8
7.1
107
619
C07AB02
ATC
metoprolol; systemic
1.6
7.1
178
1181
D02AE01
ATC
carbamide; topical
2.0
7.0
72
368
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
6.9
76
397
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
6.9
405
3190
WX892
NOMESCO Finland
Monitored bed care
1.9
6.8
80
427
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
6.8
460
3706
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.6
6.8
174
1160
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
6.1
6.8
17
28
J01MA14
ATC
moxifloxacin; systemic
1.9
6.8
89
494
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
6.8
84
458
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.3
6.7
47
205
C08CA02
ATC
felodipine; oral
1.9
6.7
81
437
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.3
6.7
25
78
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.8
6.7
103
600
B34.9
ICD-10 Finland
Viral infection, unspecified
2.5
6.7
42
175
B35.3
ICD-10 Finland
Tinea pedis
2.3
6.7
49
219
D02AX
ATC
Other emollients and protectives
2.5
6.6
39
157
C07AB07
ATC
bisoprolol; oral
1.4
6.6
434
3474
R4110
NOMESCO Finland
Physiotherapy
1.5
6.6
280
2074
B05DA
ATC
Isotonic solutions
5.9
6.6
17
29
B01AB04
ATC
dalteparin; parenteral
2.2
6.6
52
239
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.1
6.6
26
84
R01AD09
ATC
mometasone; nasal
1.4
6.6
506
4156
L01AA01
ATC
cyclophosphamide; systemic
8.7
6.6
13
15
C07AG02
ATC
carvedilol; oral
2.1
6.5
58
280
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
6.5
135
854
B01AB05
ATC
enoxaparin; parenteral
1.4
6.4
293
2200
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
6.4
188
1291
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
70.2
6.4
7
*
L30.3
ICD-10 Finland
Infective dermatitis
2.5
6.4
40
166
ZXE00
NOMESCO Finland
One hour or less
1.4
6.4
408
3250
XQ800
NOMESCO Finland
Prick test
1.8
6.3
87
490
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.6
6.3
20
56
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.8
6.3
91
520
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.3
288
2163
JN3AD
NOMESCO Finland
Abdominal CT examination
1.7
6.3
110
666
D69.4
ICD-10 Finland
Other primary thrombocytopenia
+∞
6.3
6
*
126
Kela drug reimbursment
Chronic coagulation defects
+∞
6.3
6
*
N03AX16
ATC
[U] pregabalin
1.5
6.2
223
1598
58399
ICD-8 Finland
Nephritis, unqualified
26.8
6.2
8
*
B05DB
ATC
Hypertonic solutions
6.3
6.2
15
24
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
6.3
6.2
15
24
UKC02
NOMESCO Finland
Cystoscopy
1.6
6.2
137
883
R03AC02
ATC
salbutamol; inhalant
1.3
6.1
614
5240
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
3.1
6.1
25
83
A07EC01
ATC
sulfasalazine; oral, rectal
1.8
6.1
84
474
Z2446
NOMESCO Finland
Social worker
1.8
6.1
83
467
A02BA03
ATC
famotidine; systemic
2.5
6.1
36
146
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
3.0
6.0
26
89
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
6.0
262
1949
ZXD05
NOMESCO Finland
Urgent procedure
1.4
6.0
328
2540
M79.6
ICD-10 Finland
Pain in limb
1.4
6.0
433
3509
L52
ICD-10 Finland
Erythema nodosum
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
243
366
8.05
159.85
1.8
1.5
17.36
9.13
u/ml
—
9
11
174
226
8.82
128.83
1.9
1.3
9.20
5.84
iu/ml
—
8
5
189
299
7.30
117.57
1.8
1.6
275.00
182.00
titre
—
12
10
173
294
6.70
100.03
1.6
1.5
0.24
0.24
g/l
0.29
161
282
173
307
6.41
95.71
1.6
1.5
1.22
1.19
g/l
0.44
161
292
160
360
4.97
67.56
1.3
1.2
—
—
—
0
0
329
1340
3.00
57.53
1.5
1.3
442.46
468.51
titre
0.11
65
261
217
730
3.40
52.07
10.1
7.1
9.54
8.95
mmol/l
0.58
206
693
67
87
8.09
48.85
2.5
2.7
1.05
1.87
g/24h
1.62
29
49
270
1135
2.77
43.26
9.9
5.5
1.10
1.06
mmol/l
1.29
254
1051
695
4549
2.24
40.38
9.3
6.2
—
—
—
0
0
128
379
3.66
36.91
1.3
1.2
2.48
1.31
u/ml
0.20
11
24
715
4838
2.16
36.84
8.9
5.7
0.60
0.57
e9/l
3.41
650
4206
716
4849
2.16
36.79
8.9
5.7
0.04
0.04
e9/l
2.12
650
4216
730
5016
2.14
35.66
9.4
6.0
0.19
0.19
e9/l
0.32
668
4434
665
4418
2.12
35.41
9.4
5.9
0.67
0.67
%
0.01
636
4139
725
5005
2.11
34.51
9.1
5.8
2.06
1.95
e9/l
0.55
668
4464
72
144
5.25
34.45
1.5
1.4
—
—
—
0
0
680
4600
2.09
33.97
9.6
6.1
8.40
8.43
%
0.12
648
4333
674
4573
2.07
33.05
9.4
5.8
2.75
2.85
%
0.55
645
4296
684
4701
2.04
31.95
9.0
5.7
58.01
56.74
%
2.05
655
4437
689
4760
2.04
31.58
9.4
5.8
27.73
28.60
%
1.21
659
4495
771
5575
2.05
30.76
11.2
8.5
4.39
4.05
e9/l
3.63
701
4870
403
2333
2.09
29.73
4.9
3.4
529.27
302.02
mg/l
0.44
311
1521
152
570
2.91
29.52
1.7
1.7
1.07
1.45
g/l
1.53
133
525
397
2300
2.08
29.11
5.0
3.9
—
—
—
0
0
450
2753
2.01
28.20
5.5
3.1
40.39
86.57
e6/l
1.05
357
2100
413
2462
2.03
27.75
6.0
4.0
20.08
9.59
mg/mmol
2.54
320
1579
140
519
2.92
27.71
1.7
2.4
—
—
—
0
0
106
336
3.36
27.37
5.3
3.5
0.35
0.26
g/l
0.58
65
140
156
624
2.72
26.74
1.9
2.7
67.07
66.87
g/l
0.11
148
567
412
2483
2.00
26.63
5.3
3.0
0.35
0.41
e6/l
0.14
315
1863
101
317
3.38
26.48
1.5
2.1
1.63
1.48
g/l
0.66
87
280
170
714
2.61
26.43
3.1
2.7
10.71
10.51
g/l
0.24
154
649
47
82
5.92
26.00
1.3
1.1
86.00
107.86
titre
—
10
14
405
2447
1.98
25.84
5.0
3.0
—
—
—
0
0
505
3299
1.91
25.45
6.6
3.6
41.40
89.13
e6/l
1.53
374
2260
193
880
2.42
25.13
3.3
2.7
1.87
1.75
%
0.84
175
784
437
2732
1.94
25.07
5.3
3.3
7.81
7.98
mmol/l
0.30
392
2347
156
650
2.61
24.58
6.4
4.1
115.05
82.18
ng/l
2.27
142
579
262
1382
2.14
24.00
3.7
2.3
12.40
13.72
umol/l
2.45
252
1288
33
43
7.86
23.88
1.4
1.6
—
—
—
0
0
567
3904
1.85
23.75
9.0
5.9
1.22
1.21
mmol/l
0.35
534
3571
547
3726
1.85
23.71
7.7
4.6
35.02
36.19
g/l
5.06
516
3471
231
1168
2.21
23.51
3.9
2.4
21.58
23.78
%
1.44
204
1011
839
6630
1.86
21.42
7.0
4.0
—
—
—
0
0
239
1267
2.10
21.39
3.8
2.3
2.33
2.36
g/l
0.42
227
1174
604
4336
1.78
21.22
10.6
6.4
1.22
1.21
mmol/l
0.15
522
3713
381
2385
1.87
21.04
8.1
6.2
—
—
—
0
0
266
1481
2.02
20.78
4.0
2.7
0.81
1.05
e6/l
0.72
155
817
144
627
2.47
20.57
2.9
2.4
76.13
70.50
e9/l
0.87
110
472
315
1879
1.91
20.04
4.5
2.5
4.81
6.45
e6/l
1.36
293
1690
305
1804
1.92
19.89
5.1
2.8
528.49
546.61
mosm/kgh2o
0.81
274
1562
395
2561
1.80
19.13
7.1
3.9
7.39
7.40
ph
1.23
74
478
24
7
34.93
18.94
1.2
1.1
—
—
—
0
0
37
70
5.42
18.80
1.2
1.1
—
—
—
0
0
340
2131
1.83
18.27
1.6
1.4
3.01
2.30
g/l
9.06
223
1330
353
2238
1.81
18.27
3.1
2.5
2855.71
6585.95
umol/l
1.11
317
1993
233
1303
1.98
17.72
3.0
2.0
29.79
29.59
s
0.21
224
1259
855
6978
1.76
17.52
6.2
3.9
14.22
10.83
mm/h
7.48
812
6476
248
1422
1.94
17.51
4.5
2.9
2.86
2.35
e6/l
0.36
135
761
538
3888
1.69
17.26
4.5
3.2
5.65
5.88
ph
1.10
41
340
336
2130
1.80
17.24
4.9
3.4
—
—
—
0
0
866
7119
1.76
17.00
10.4
6.9
78.02
76.84
u/l
0.37
828
6706
631
4768
1.67
16.99
5.1
3.4
0.00
0.00
estimate
0.50
123
969
634
4811
1.67
16.67
5.2
3.4
0.00
0.01
estimate
0.80
122
890
238
1367
1.92
16.64
2.0
1.6
—
—
—
0
0
629
4768
1.66
16.57
7.2
4.6
0.00
0.00
estimate
0.50
122
925
778
6276
1.67
15.68
5.5
4.1
608.62
2148.74
e6/l
0.89
13
95
171
896
2.06
15.48
2.4
2.0
337.13
375.54
nmol/l
1.91
157
831
28
49
5.83
15.44
1.2
1.1
389.23
159.05
iu/ml
1.34
28
49
140
680
2.20
15.42
5.1
3.3
—
—
—
0
0
233
1364
1.88
15.26
4.2
3.4
0.79
0.82
mmol/l
3.11
221
1284
69
241
2.98
15.12
1.3
1.2
1.61
2.76
u/ml
—
8
29
574
4321
1.62
15.01
12.6
8.6
0.00
0.00
e9/l
0.32
476
3515
69
245
2.93
14.68
1.3
1.2
4.43
9.73
u/ml
—
9
42
72
262
2.86
14.66
1.3
1.2
65.10
24.72
u/ml
—
6
13
199
1130
1.91
14.25
2.2
1.6
—
—
—
0
0
524
3904
1.60
13.99
2.9
2.3
74.60
74.86
nmol/l
0.08
490
3544
518
3852
1.60
13.92
17.5
12.7
1.25
1.21
inr
0.48
160
1191
163
878
1.99
13.60
1.5
1.5
—
—
—
0
0
144
750
2.04
13.18
4.7
4.3
1.21
0.98
%
0.39
61
249
212
1275
1.80
12.55
2.2
2.0
—
—
—
0
0
30
68
4.50
12.42
1.3
2.2
—
—
—
0
0
316
2132
1.65
12.32
2.0
1.8
1.01
1.06
mg/l
0.11
240
1580
136
718
2.01
11.96
4.8
4.4
0.13
0.12
%
0.06
54
216
296
1985
1.65
11.75
1.9
1.7
—
—
—
0
0
33
85
3.96
11.60
1.9
2.4
1.02
1.27
e9/l
0.77
28
74
64
248
2.67
11.60
3.8
3.1
—
—
—
0
0
594
4690
1.52
11.49
7.1
5.7
10.59
11.03
umol/l
0.46
569
4446
47
156
3.09
11.28
1.3
1.7
—
—
—
0
0
46
152
3.11
11.13
1.3
1.2
3.81
3.87
u/ml
0.02
21
62
656
5332
1.50
10.77
5.6
4.6
6.46
6.57
mmol/l
0.74
624
4941
25
55
4.62
10.74
1.2
1.0
—
—
—
0
0
336
2368
1.58
10.74
2.8
2.1
2.94
2.90
mg/l
0.08
300
2028
127
683
1.96
10.58
4.7
4.2
1.12
0.63
%
0.67
52
213
43
141
3.12
10.55
1.5
1.4
0.84
0.65
g/l
0.37
31
107
126
686
1.93
10.12
4.8
4.4
0.09
0.14
%
0.29
44
181
130
721
1.90
9.88
8.8
8.5
—
—
—
0
0
35
106
3.37
9.77
1.2
1.2
—
—
—
0
0
61
252
2.50
9.74
1.7
2.5
10.06
11.64
mg/l
0.84
53
232
573
4594
1.47
9.68
3.7
2.7
123.99
105.99
ug/l
0.96
542
4281
357
2602
1.53
9.65
2.2
2.1
209.17
257.31
u/l
0.40
337
2464
370
2724
1.52
9.51
3.5
2.8
—
—
—
0
0
227
1497
1.64
9.43
1.8
1.7
1204.38
1188.68
nmol/l
0.10
179
1146
51
199
2.63
9.16
2.0
1.4
111.66
103.67
u/ml
0.37
14
34
244
1650
1.60
9.12
1.3
1.3
24.76
30.30
iu/ml
0.55
73
535
109
587
1.94
9.04
5.7
3.5
7.42
7.40
ph
—
6
64
29
82
3.60
8.98
1.3
1.3
2.53
2.70
g/l
0.24
21
57
29
82
3.60
8.98
1.3
1.3
5.47
6.29
g/l
0.92
21
58
29
82
3.60
8.98
1.3
1.3
0.37
0.36
g/l
0.09
21
56
53
213
2.56
8.98
1.9
1.5
—
—
—
0
0
138
815
1.78
8.57
7.0
3.6
1.72
1.78
mmol/l
0.08
116
677
86
445
2.00
8.01
6.4
3.4
—
—
—
0
0
333
2473
1.48
7.97
2.2
2.0
—
—
—
0
0
28
84
3.39
7.96
1.3
1.3
—
—
—
0
0
24
65
3.75
7.92
1.9
2.4
0.20
0.21
e9/l
0.09
19
55
68
328
2.14
7.64
3.1
2.2
21.05
21.35
s
0.25
60
293
134
811
1.73
7.64
3.1
2.3
0.20
0.22
g/l
2.32
127
760
375
2870
1.44
7.62
2.8
2.5
56.41
59.73
u/l
0.60
346
2670
385
2963
1.44
7.58
4.4
3.1
2.35
2.35
mmol/l
0.20
344
2634
146
907
1.69
7.57
6.2
8.3
0.51
1.15
mmol/l
1.14
116
728
51
220
2.38
7.47
1.8
4.0
31.02
30.88
mg/l
0.01
45
172
297
2186
1.47
7.36
3.5
3.2
1635.70
1208.57
ng/l
0.77
250
1833
1061
9833
1.63
7.31
21.6
12.3
20.29
22.18
mg/l
1.37
908
7657
24
69
3.53
7.29
1.9
2.4
372.21
531.39
e6/l
0.88
19
56
35
127
2.81
7.27
3.4
3.0
1.27
1.44
%
0.12
30
116
53
236
2.30
7.24
1.4
1.3
244.19
245.43
u/ml
0.01
37
139
416
3271
1.41
7.20
4.2
3.4
31.33
39.89
ng/l
0.62
283
2039
144
908
1.66
7.05
6.3
8.3
4.90
5.14
kpa
2.53
139
867
50
220
2.33
7.02
1.9
4.0
41.55
81.04
mg/l
0.70
44
173
39
154
2.58
6.90
5.8
2.6
—
—
—
0
0
81
439
1.91
6.63
1.4
1.3
—
—
—
0
0
136
861
1.65
6.56
2.5
2.4
34.17
91.93
u/l
0.52
124
729
111
670
1.72
6.39
1.4
1.2
196.59
242.67
u/ml
0.38
100
626
26
89
2.96
6.02
3.9
3.5
—
—
—
0
0
50
237
2.16
5.93
1.2
1.3
—
—
—
0
0
434
3532
1.36
5.81
2.0
1.9
93.74
96.08
pmol/l
0.50
244
1834
191
1345
1.50
5.80
2.5
2.5
98.79
120.47
ug/g
0.75
163
1069
154
1039
1.55
5.70
7.2
6.7
104.84
104.34
mmol/l
0.63
154
1039
160
1089
1.54
5.69
1.7
1.4
—
—
—
0
0
217
1574
1.46
5.67
1.3
1.2
12.39
13.02
u/ml
0.04
74
635
1044
9760
1.50
5.59
22.8
13.7
139.38
139.61
mmol/l
2.31
1023
9505
1046
9787
1.50
5.53
23.1
13.8
3.95
3.95
mmol/l
0.34
1025
9511
40
179
2.28
5.46
6.1
3.8
55.18
57.28
%
0.51
40
179
177
1244
1.50
5.41
1.4
1.2
—
—
—
0
0
38
167
2.32
5.41
1.1
1.1
—
—
—
0
0
60
316
1.95
5.39
2.0
1.7
1.52
2.23
ug/l
0.23
51
277
23
79
2.95
5.32
2.5
2.8
57.72
55.28
%
0.21
18
71
15
30
5.05
5.26
1.3
1.2
—
—
—
0
0
16
44
3.67
5.21
1.1
1.5
—
—
—
0
0
393
3193
1.34
5.20
3.4
3.0
36.07
32.30
u/l
0.60
369
3044
17
49
3.50
5.18
1.1
1.2
—
—
—
0
0
71
403
1.81
5.08
2.0
1.7
—
—
—
0
0
321
2537
1.36
5.07
5.9
3.7
0.00
0.01
estimate
1.08
113
898
19
60
3.20
5.05
1.1
1.2
—
—
—
0
0
108
696
1.61
4.87
1.4
1.4
—
—
—
0
0
40
189
2.15
4.83
4.1
3.4
2.13
2.48
mmol/l
0.36
31
123
38
176
2.20
4.82
5.9
3.5
4.07
4.29
e9/l
0.32
38
176
220
1647
1.41
4.81
4.6
3.5
735.92
513.61
ng/l
0.16
160
1174
51
265
1.97
4.79
1.2
1.2
76.67
87.39
titre
—
9
23
72
420
1.76
4.72
7.8
11.4
—
—
—
0
0
39
186
2.13
4.61
4.1
3.0
—
—
—
0
0
23
86
2.71
4.60
3.5
2.8
—
—
—
0
0
936
8669
1.35
4.53
23.4
14.8
14.63
15.06
%
0.37
925
8524
35
163
2.18
4.40
1.9
1.4
—
—
—
0
0
305
2446
1.33
4.29
1.3
1.3
1.14
1.56
u/ml
0.52
89
663
37
179
2.10
4.24
1.1
1.1
—
—
—
0
0
14
34
4.15
4.21
6.2
5.5
—
—
—
0
0
82
514
1.64
4.17
4.3
5.6
—
—
—
0
0
54
301
1.83
4.15
2.7
2.7
—
—
—
0
0
79
494
1.64
4.06
7.1
10.2
94.74
94.34
%
0.40
79
489
13
31
4.23
4.02
1.1
1.0
—
—
—
0
0
19
70
2.74
3.93
1.8
1.5
16.14
33.08
%
2.19
14
51
13
32
4.10
3.90
1.0
1.0
—
—
—
0
0
264
2101
1.33
3.88
5.4
3.7
1.02
1.02
kg/l
0.24
46
281
145
1048
1.44
3.85
3.0
2.4
8.47
7.79
umol/l
0.14
130
905
31
146
2.15
3.83
1.6
1.7
—
—
—
0
0
12
28
4.32
3.82
1.8
2.3
195.71
252.67
e6/l
—
7
15
26
115
2.29
3.73
3.0
3.1
—
—
—
0
0
12
30
4.03
3.60
1.0
1.0
—
—
—
0
0
24
105
2.31
3.54
3.9
3.3
—
—
—
0
0
84
556
1.55
3.44
1.3
1.2
—
—
—
0
0
31
154
2.04
3.37
1.2
1.2
—
—
—
0
0
1084
10399
1.40
3.24
14.5
9.2
27.18
26.75
u/l
0.33
1063
10072
139
1035
1.39
3.14
1.4
1.3
—
—
—
0
0
11
30
3.69
3.09
2.6
2.1
—
—
—
0
0
735
6745
1.23
3.03
3.7
3.0
53.00
43.11
u/l
2.58
695
6381
22
100
2.22
3.00
2.0
1.8
65.87
61.23
%
0.22
15
74
195
1540
1.32
3.00
3.4
2.9
2.47
2.44
mmol/l
1.95
173
1340
27
134
2.04
2.97
1.3
1.5
—
—
—
0
0
37
205
1.83
2.97
1.5
1.8
10015.74
15874.14
e6/l
0.70
27
153
16
63
2.56
2.96
4.0
2.9
—
—
—
0
0
20
88
2.29
2.94
1.3
1.1
—
—
—
0
0
63
406
1.58
2.93
2.5
2.3
—
—
—
0
0
271
2241
1.27
2.93
2.7
2.2
—
—
—
0
0
29
149
1.97
2.91
2.7
2.9
—
—
—
0
0
17
70
2.45
2.88
3.8
3.0
11.45
10.97
%
0.24
17
70
7
13
5.41
2.87
11.3
4.9
6.04
7.77
mmol/l
—
7
13
96
681
1.44
2.86
6.2
3.3
1.22
1.23
mmol/l
0.72
88
586
32
172
1.88
2.83
1.7
4.1
—
—
—
0
0
11
33
3.35
2.81
1.1
1.8
—
—
—
0
0
814
7577
1.23
2.80
4.2
3.9
14.65
14.62
pmol/l
0.14
753
6967
8
18
4.47
2.79
1.0
1.1
—
—
—
0
0
15
59
2.56
2.79
1.0
1.1
—
—
—
0
0
345
2950
1.24
2.77
3.0
2.2
—
—
—
0
0
5
6
8.36
2.75
1.0
1.0
—
—
—
0
0
11
34
3.26
2.73
1.1
1.1
—
—
—
0
0
6
10
6.02
2.70
2.7
1.6
—
—
—
0
0
6
10
6.02
2.70
1.5
1.3
177.00
93.20
ng/l
—
6
10
27
140
1.95
2.66
2.6
3.0
0.88
0.87
nmol/l
0.02
16
110
322
2744
1.24
2.66
4.6
3.0
—
—
—
0
0
245
2025
1.26
2.65
1.7
1.5
20.17
20.60
nmol/l
0.15
223
1737
19
86
2.23
2.64
1.3
1.5
1457.50
210932.67
e6/l
1.13
14
60
92
659
1.43
2.62
2.5
2.7
7.64
5.82
e9/l
0.26
75
561
422
3706
1.21
2.59
2.2
2.0
—
—
—
0
0
110
818
1.38
2.53
6.6
3.8
—
—
—
0
0
498
4453
1.20
2.51
2.9
2.5
—
—
—
0
0
78
547
1.46
2.49
1.2
1.1
—
182.60
—
0
10
15
63
2.40
2.47
1.1
1.0
—
—
—
0
0
12
45
2.68
2.45
2.1
4.0
104.00
131.75
umol/l
—
6
24
17
76
2.25
2.45
1.4
1.3
—
—
—
0
0
20
96
2.10
2.43
1.2
1.1
—
—
—
0
0
946
8993
1.24
2.43
5.1
4.6
1.84
2.10
mu/l
0.77
894
8346
25
133
1.90
2.32
2.3
2.4
—
—
—
0
0
168
1349
1.28
2.30
1.5
1.5
—
—
—
0
0
42
262
1.62
2.29
1.4
1.4
313.32
309.23
ug/g
0.04
25
149
6
13
4.63
2.27
1.0
1.1
—
—
—
0
0
30
171
1.77
2.26
2.2
2.3
16.89
16.34
%
0.25
12
81
33
194
1.72
2.24
5.4
3.0
—
—
—
0
0
28
157
1.80
2.23
1.2
1.2
—
—
—
0
0
5
9
5.57
2.21
1.2
1.1
—
—
—
0
0
12
48
2.51
2.19
1.0
1.1
—
14.80
—
0
5
90
665
1.38
2.18
2.6
2.3
6.78
7.50
ug/l
0.12
77
585
1071
10362
1.29
2.13
19.1
11.4
—
—
—
0
0
21
109
1.94
2.11
2.0
1.5
—
—
—
0
0
9
31
2.92
2.07
2.0
1.7
—
—
—
0
0
9
31
2.92
2.07
1.2
2.6
—
—
—
0
0
7
20
3.51
2.05
3.4
1.5
—
—
—
0
0
684
6357
1.17
2.05
3.8
3.4
—
—
—
0
0
896
8519
1.20
2.05
6.0
5.0
39.09
39.03
mmol/mol
0.06
845
7989
10
39
2.58
1.94
1.1
1.7
28.70
29.26
umol/l
—
10
39
85
636
1.36
1.94
1.5
1.4
—
—
—
0
0
22
121
1.83
1.89
1.2
1.2
—
—
—
0
0
85
640
1.35
1.87
3.1
2.9
238.59
184.54
ng/l
0.65
75
581
142
1148
1.27
1.87
1.3
1.3
—
—
—
0
0
46
310
1.50
1.85
4.7
4.7
—
—
—
0
0
215
1823
1.22
1.84
1.6
1.6
424.61
23779345.04
pmol/l
1.77
187
1556
20
108
1.87
1.82
2.0
1.6
—
—
—
0
0
96
740
1.32
1.81
1.9
2.2
12.83
12.93
nmol/l
0.04
80
678
108
848
1.30
1.79
6.4
3.5
—
—
—
0
0
8
29
2.77
1.79
2.5
1.2
106.37
82.76
nmol/24h
—
8
29
60
430
1.42
1.78
1.2
1.3
246.96
222.72
miu/ml
0.19
27
212
11
47
2.35
1.78
1.0
1.1
2039.00
1626.98
miu/ml
0.58
11
47
127
1021
1.27
1.76
1.4
1.4
—
—
—
0
0
5
13
3.86
1.71
1.2
1.0
—
—
—
0
0
107
845
1.29
1.71
1.2
1.2
—
—
—
0
0
6
19
3.17
1.66
3.7
1.6
—
—
—
0
0
45
311
1.46
1.63
1.3
1.1
—
—
—
0
0
16
84
1.92
1.60
1.4
1.3
31.52
32.60
g/l
0.10
16
72
14
70
2.01
1.59
1.4
1.5
—
—
—
0
0
10
44
2.28
1.55
5.1
2.5
—
—
—
0
0
10
45
2.23
1.46
1.0
1.1
—
—
—
0
0
20
117
1.72
1.45
1.2
1.3
0.49
0.56
nmol/l
0.66
20
108
7
28
2.51
1.45
1.6
1.2
—
—
—
0
0
79
615
1.30
1.44
2.8
2.6
—
—
—
0
0
14
74
1.90
1.39
1.3
1.2
—
—
—
0
0
9
41
2.20
1.37
1.2
3.7
869.33
579.98
u/ml
—
9
41
42
298
1.42
1.37
1.3
1.2
—
—
—
0
0
60
454
1.34
1.34
1.0
1.1
—
—
—
0
0
11
54
2.05
1.33
2.8
3.2
45200.00
40885.28
ug/l
0.16
11
54
33
226
1.47
1.30
2.6
2.3
—
—
—
0
0
13
69
1.89
1.28
3.8
1.9
—
—
—
0
0
169
1454
1.19
1.27
1.8
1.7
—
—
—
0
0
9
44
2.05
1.27
3.0
1.6
3.12
6.24
nmol/l
—
9
37
23
146
1.59
1.26
1.5
1.6
—
—
—
0
0
77
610
1.28
1.25
1.3
1.2
—
—
—
0
0
58
752
0.76
1.25
1.5
1.3
—
—
—
0
0
40
287
1.41
1.24
3.4
4.2
1.24
1.35
mmol/l
0.38
40
281
8
36
2.23
1.24
1.5
2.3
42.13
71.55
ug/l
—
8
36
5
19
2.64
1.21
3.4
1.8
—
—
—
0
0
18
109
1.66
1.19
1.2
1.3
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
5
20
2.51
1.15
1.2
1.2
—
—
—
0
0
26
176
1.49
1.11
1.7
1.4
21.39
22.38
u/l
0.06
17
147
7
32
2.19
1.08
1.1
1.1
—
—
—
0
0
25
169
1.49
1.07
1.1
1.1
12.15
5.82
u/ml
—
7
67
13
74
1.76
1.07
1.1
1.0
308.15
293.58
mg/l
0.24
13
65
268
2425
1.13
1.05
4.5
3.6
—
—
—
0
0
340
3688
0.89
1.04
2.6
2.5
—
—
—
0
0
54
422
1.29
1.01
5.1
3.2
—
—
—
0
0
12
68
1.77
1.00
1.3
1.1
—
—
—
0
0
5
23
2.18
0.98
6.6
4.3
57.40
51.63
%
—
5
23
24
168
1.44
0.90
1.9
1.9
4.73
4.91
mmol/24h
0.09
19
150
11
64
1.73
0.86
1.5
1.3
—
—
—
0
0
70
579
1.22
0.85
1.5
2.3
262.09
4921.78
u/l
4.16
22
232
74
617
1.21
0.83
3.7
3.3
4.49
4.62
pmol/l
0.39
64
545
47
375
1.26
0.79
1.4
1.5
10.45
8.99
u/l
0.26
34
303
8
48
1.67
0.79
1.1
1.6
1.29
1.11
nmol/l
—
8
37
30
226
1.34
0.77
1.1
1.1
2.08
1.73
u/ml
0.07
11
104
25
336
0.74
0.76
1.6
1.5
—
—
—
0
0
9
53
1.70
0.75
1.4
3.2
—
—
—
0
0
12
75
1.61
0.75
24.8
11.4
0.60
0.64
mmol/l
0.30
12
67
7
38
1.85
0.73
1.3
1.1
—
—
—
0
0
7
39
1.80
0.72
1.3
1.3
—
—
—
0
0
7
39
1.80
0.72
3.7
2.8
—
—
—
0
0
12
76
1.58
0.71
1.2
1.1
—
—
—
0
0
1125
11114
1.17
0.71
30.1
18.0
40.05
40.81
%
1.01
1070
10489
9
57
1.58
0.71
1.3
1.2
—
—
—
0
0
7
41
1.71
0.70
1.1
3.6
—
—
—
0
0
1126
11128
1.17
0.69
30.0
17.9
7.19
6.70
e9/l
8.89
1105
10846
28
214
1.32
0.67
5.4
4.1
—
—
—
0
0
25
328
0.76
0.67
1.6
1.4
—
—
—
0
0
1126
11131
1.16
0.66
30.1
18.0
134.20
136.29
g/l
5.10
1110
10989
25
327
0.76
0.65
1.6
1.4
—
—
—
0
0
74
635
1.18
0.65
1.4
2.1
—
—
—
0
0
15
103
1.46
0.65
3.3
1.8
—
—
—
0
0
15
103
1.46
0.65
5.0
2.5
—
—
—
0
0
130
1164
1.13
0.64
1.6
1.8
—
—
—
0
0
1125
11125
1.15
0.63
29.8
17.8
30.07
30.17
pg
1.03
1112
10988
1125
11125
1.15
0.63
29.9
17.9
90.45
90.37
fl
0.23
1112
10989
1124
11115
1.15
0.63
30.2
17.9
252.62
254.18
e9/l
0.33
1101
10859
37
297
1.25
0.63
1.5
2.9
—
—
—
0
0
12
79
1.52
0.62
1.2
1.5
14.12
12.11
umol/l
0.50
12
72
1125
11127
1.15
0.62
30.0
17.9
4.49
4.54
e12/l
2.70
1102
10850
11
71
1.55
0.62
2.0
1.8
—
—
—
0
0
30
236
1.28
0.60
1.1
1.1
5.86
8.58
u/ml
0.39
15
127
24
183
1.32
0.60
2.0
2.3
131.38
130.53
g/l
0.06
16
138
69
594
1.17
0.59
1.4
2.3
—
—
—
0
0
0
22
0.00
0.59
0.0
6.3
—
—
—
0
0
14
97
1.45
0.59
8.5
8.0
5.66
6.89
mmol/l
—
9
79
15
106
1.42
0.57
1.5
1.1
—
—
—
0
0
12
172
0.69
0.56
2.0
1.6
—
—
—
0
0
50
421
1.20
0.56
1.1
1.1
—
—
—
0
0
5
88
0.57
0.56
1.2
1.4
1.44
1.41
nmol/l
—
5
78
73
637
1.16
0.54
1.4
2.2
—
—
—
0
0
25
195
1.29
0.54
2.2
1.4
0.33
0.35
nmol/l
0.07
17
159
26
204
1.28
0.54
2.5
2.3
161.09
101.32
ug/min
0.33
17
125
28
222
1.27
0.54
1.1
1.1
—
—
—
0
0
22
169
1.31
0.53
1.1
1.1
—
—
—
0
0
28
223
1.26
0.52
1.1
1.1
—
—
—
0
0
24
188
1.28
0.51
1.1
1.0
0.95
3.90
u/ml
—
7
92
28
224
1.26
0.51
1.1
1.1
0.27
2.29
u/ml
—
9
116
73
642
1.15
0.50
1.4
2.2
—
—
—
0
0
14
101
1.39
0.49
2.0
1.9
31.50
32.56
pg
0.32
14
101
7
45
1.56
0.49
1.9
1.6
—
21.38
—
0
5
11
76
1.45
0.48
1.1
1.4
137.54
183.73
pmol/l
0.68
11
76
73
645
1.14
0.48
1.4
2.2
—
—
—
0
0
19
146
1.31
0.47
2.1
1.5
—
—
—
0
0
21
266
0.79
0.47
1.7
1.9
7.35
5.26
iu/l
0.29
11
97
65
575
1.14
0.43
1.4
1.4
18.87
24.53
iu/l
0.98
57
480
928
9421
0.94
0.43
4.5
3.9
1.41
1.46
mmol/l
3.47
880
8802
43
369
1.17
0.42
1.7
1.7
—
—
—
0
0
10
70
1.43
0.41
1.6
1.5
—
—
—
0
0
58
511
1.14
0.41
1.4
2.3
—
—
—
0
0
10
71
1.41
0.39
1.2
1.2
—
—
—
0
0
9
68
1.33
0.37
1.2
1.1
—
—
—
0
0
31
262
1.19
0.37
1.2
1.1
0.59
3.68
u/ml
3.40
14
139
111
1198
0.92
0.35
1.2
1.3
—
—
—
0
0
6
43
1.40
0.35
1.2
1.3
134.83
153.77
nmol/l
—
6
43
283
2953
0.95
0.34
1.5
1.5
—
—
—
0
0
20
163
1.23
0.34
1.0
1.1
294.24
90.48
iu/ml
—
9
40
6
45
1.33
0.33
1.0
1.0
250.00
247.37
ng/l
—
6
27
6
45
1.33
0.33
1.0
1.0
1113.33
610.67
ng/l
—
6
27
936
9469
0.95
0.31
4.6
3.9
4.60
4.68
mmol/l
1.77
890
8893
11
142
0.77
0.30
1.4
1.1
—
—
—
0
0
83
767
1.09
0.28
4.5
4.2
6.78
22.31
ug/l
0.83
66
624
27
310
0.87
0.26
1.4
1.3
—
—
—
0
0
67
617
1.09
0.26
2.0
1.6
—
—
—
0
0
9
73
1.23
0.25
1.0
1.0
—
—
—
0
0
6
85
0.70
0.24
11.0
15.4
651.17
814.21
nmol/l
—
6
80
5
38
1.32
0.23
2.4
1.2
—
—
—
0
0
5
38
1.32
0.23
1.4
1.1
—
—
—
0
0
40
441
0.90
0.22
1.5
3.0
—
—
—
0
0
22
191
1.15
0.22
4.8
2.9
1.42
1.52
mmol/l
0.35
22
186
0
11
0.00
0.21
0.0
1.0
—
0.36
—
0
5
0
11
0.00
0.21
0.0
2.6
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
0.21
—
0
5
0
11
0.00
0.21
0.0
2.8
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
3.2
—
—
—
0
0
0
13
0.00
0.21
0.0
3.1
—
5898.62
—
0
13
0
14
0.00
0.20
0.0
7.6
—
—
—
0
0
883
8750
1.03
0.19
25.4
15.4
331.78
333.13
g/l
4.50
875
8697
6
53
1.13
0.18
1.0
1.2
—
—
—
0
0
249
2420
1.04
0.18
1.7
1.6
1.47
1.38
mmol/l
0.75
223
2071
8
68
1.18
0.16
1.4
1.2
6.99
6.60
mmol/l
—
8
63
928
9213
1.03
0.16
4.9
4.0
5.84
5.83
mmol/l
0.12
866
8477
9
80
1.13
0.15
2.7
2.6
—
—
—
0
0
957
9620
0.98
0.12
4.9
4.3
2.70
2.80
mmol/l
3.23
905
8977
21
192
1.10
0.11
1.0
1.6
—
—
—
0
0
21
229
0.92
0.11
1.1
1.2
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
175.00
167.60
mmol/24h
—
5
44
249
2450
1.02
0.09
4.1
4.5
1.77
2.42
ug/l
1.85
223
2217
12
107
1.12
0.08
1.2
1.3
—
—
nmol/l
—
0
0
6
58
1.03
0.08
1.0
1.2
—
—
—
0
0
5
61
0.82
0.08
1.4
1.4
1.54
1.55
g/l
—
5
61
8
77
1.04
0.07
1.8
1.3
107.00
75.82
umol/l
—
8
77
75
772
0.97
0.07
1.3
1.2
118.51
147.52
iu/ml
0.35
28
311
9
88
1.02
0.07
1.2
1.1
—
—
—
0
0
8
93
0.86
0.06
1.3
1.9
—
—
—
0
0
28
295
0.95
0.06
15.5
9.2
—
—
—
0
0
20
213
0.94
0.06
1.1
1.1
—
—
—
0
0
31
296
1.05
0.06
3.2
3.1
160.96
1171.16
u/ml
1.00
26
255
146
1437
1.02
0.05
2.7
2.8
0.70
0.74
ug/l
0.24
91
877
20
212
0.94
0.05
4.7
3.6
23.64
26.85
mg/l
0.21
13
134
20
212
0.94
0.05
1.2
1.3
—
—
—
0
0
48
495
0.97
0.05
1.9
1.5
430.86
298.89
mu/l
0.92
42
441
902
9041
0.99
0.04
4.2
3.5
1.39
1.27
mmol/l
3.83
853
8403
10
108
0.93
0.03
1.3
2.2
—
—
—
0
0
14
146
0.96
0.00
5.8
3.3
70.79
24.99
u/ml
0.44
14
141
8
79
1.01
0.00
1.4
1.7
6.03
6.52
mmol/l
—
8
54
5
49
1.02
0.00
2.4
2.2
2.00
2.15
ug/l
—
5
41
6
64
0.94
0.00
1.7
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
52
0.96
-0.00
1.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
9.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
15.36
—
0
8
0
7
0.00
-0.00
0.0
1.3
—
87.86
—
0
7
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
9
89
1.01
-0.00
1.0
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.1
—
1.23
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
0.08
—
0
5
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
4.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint D3_ALLERGPURPURA and mortality.

Females

Parameter HR [95% CI] p-value
D3_ALLERGPURPURA 1.684 [1.48, 1.91] < 0.001
Birth year 0.999 [0.99, 1.01] 0.726

During the follow-up period (1.1.1998 — 31.12.2019), 714 out of 4075 females with D3_ALLERGPURPURA died.

Males

Parameter HR [95% CI] p-value
D3_ALLERGPURPURA 2.061 [1.77, 2.4] < 0.001
Birth year 0.987 [0.98, 1.0] 0.006

During the follow-up period (1.1.1998 — 31.12.2019), 715 out of 3988 males with D3_ALLERGPURPURA died.

Mortality risk

Mortality risk for people of age

years, who have D3_ALLERGPURPURA.

N-year risk Females Males
1 0.196% 0.383%
5 1.231% 2.411%
10 2.985% 5.958%
15 5.514% 11.65%
20 9.794% 19.138%

Relationships between endpoints

Index endpoint: D3_ALLERGPURPURA – Allergic purpura

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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