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Henoch-Schönlein purpura nephritis (HSPN)

Endpoint Browser PheWeb

N14_HENOCHSCHONLEIN_NEPHRITIS

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

130

4. Check minimum number of events

None

130

5. Include endpoints

None

130

6. Filter based on genotype QC (FinnGen only)

130

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1118 469 646
Only index persons 1031 442 589
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 22.53 20.27 24.01
Only index persons 23.01 21.65 24.04

-FinnGen-

Key figures

All Female Male
Number of individuals 130 66 64
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 43.22 33.18 53.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
118
Matched controls
1179
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
159.4
114
*
D69.0
ICD-10 Finland
Allergic purpura
684.4
87.3
76
*
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
+∞
60.8
53
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
52.0
46
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
71.5
35.2
39
8
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
267.6
22.4
22
*
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
20.4
19
*
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
42.5
19.8
24
7
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.9
18.8
38
49
N18.8
ICD-10 Finland
Other chronic renal failure
40.3
18.8
23
7
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
79.4
18.4
20
*
TK800
NOMESCO Finland
Hemodialysis
50.4
18.0
21
5
Z49.1
ICD-10 Finland
Extracorporeal dialysis
105.3
17.1
18
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
36.0
16.8
21
7
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
7.7
16.7
43
82
H02AB06
ATC
prednisolone; systemic
5.3
16.2
81
343
A12AA04
ATC
calcium carbonate; oral
52.6
15.6
18
*
A11CC03
ATC
alfacalcidol; systemic
37.3
15.3
19
6
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.7
14.3
73
301
KA1AE
NOMESCO Finland
Kidney ultrasound examination
17.9
13.7
21
14
Z94.0
ICD-10 Finland
Kidney transplant status
78.6
12.9
14
*
B03XA02
ATC
darbepoetin alfa; parenteral
34.0
12.0
15
5
L04AA06
ATC
mycophenolic acid; systemic
26.1
11.9
16
7
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.4
11.9
53
183
C03CA01
ATC
furosemide; systemic
4.8
11.9
46
138
205
Kela drug reimbursment
Chronic hypertension
4.8
11.9
46
138
M36.4*D69.0
ICD-10 Finland
Arthropathy in Henoch(-Schönlein) purpura
+∞
11.6
11
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
11.0
11.6
22
24
V03AE01
ATC
polystyrene sulfonate; oral
48.3
11.2
13
*
127
Kela drug reimbursment
Transplant complication
31.4
11.0
14
5
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
120.3
10.6
11
*
C09CA01
ATC
losartan; oral
4.7
10.6
41
121
V03AE02
ATC
sevelamer; oral
+∞
10.6
10
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
44.2
10.2
12
*
L04AD01
ATC
ciclosporin; systemic
22.4
10.1
14
7
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.6
10.0
19
21
H02AB04
ATC
methylprednisolone; systemic
5.2
9.2
30
73
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
40.0
9.2
11
*
C09AA02
ATC
enalapril; systemic
4.3
9.0
37
114
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.8
8.8
31
82
M10.9
ICD-10 Finland
Gout, unspecified
9.0
8.8
18
23
R31
ICD-10 Finland
Unspecified haematuria
5.8
8.7
25
52
137
Kela drug reimbursment
Uraemia requiring dialysis
30.0
8.6
11
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
96.7
8.5
9
*
B03XA01
ATC
erythropoietin; parenteral
96.7
8.5
9
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
+∞
8.4
8
*
L95.8
ICD-10 Finland
Other vasculitis limited to skin
+∞
8.4
8
*
H05BX01
ATC
cinacalcet; oral
+∞
8.4
8
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
16.0
8.4
13
9
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.7
8.3
21
37
L04AA01
ATC
[U] ciclosporin; systemic
18.9
8.3
12
7
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
48.2
7.8
9
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
48.2
7.8
9
*
C08CA01
ATC
amlodipine; oral
3.3
7.7
49
209
L04AX01
ATC
azathioprine; systemic
7.1
7.6
18
29
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
14.7
7.6
12
9
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
85.2
7.5
8
*
B05DA
ATC
Isotonic solutions
32.2
7.3
9
*
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
32.2
7.3
9
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.6
7.1
34
118
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
10.3
7.0
13
14
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
42.6
6.8
8
*
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
42.6
6.8
8
*
TK820
NOMESCO Finland
Peritoneal dialysis
42.6
6.8
8
*
Z49.2
ICD-10 Finland
Other dialysis
24.1
6.8
9
*
V03AE03
ATC
lanthanum carbonate; oral
73.7
6.5
7
*
C07AB02
ATC
metoprolol; systemic
3.8
6.4
28
90
C07AG02
ATC
carvedilol; oral
8.4
6.3
13
17
M05BA04
ATC
alendronic acid; oral
8.0
6.1
13
18
E0000UV
ATC
NA
2.7
6.0
55
289

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
84
114
19.00
67.42
17.8
6.7
1.2
1.1
mmol/l
2.92
79
104
93
238
11.22
41.46
9.0
3.2
228.4
74.4
mg/l
2.59
86
153
33
32
13.48
31.11
10.1
3.1
0.4
0.3
g/l
0.63
25
16
53
114
7.16
25.94
7.3
2.1
23.9
22.6
%
0.24
45
97
44
95
6.49
21.03
11.6
3.6
—
—
—
0
0
43
93
6.41
20.47
11.8
3.2
1.0
1.7
mmol/l
0.72
37
72
81
305
5.39
20.30
10.7
2.9
58.6
242.4
e6/l
0.42
73
239
39
80
6.54
19.52
13.3
8.8
—
—
—
0
0
75
276
5.06
19.06
10.2
2.7
0.1
0.4
e6/l
1.92
67
208
50
132
5.53
19.03
1.6
1.4
884.4
340.7
titre
—
9
29
97
441
5.73
18.79
25.8
7.9
1.2
1.2
mmol/l
0.06
83
367
73
274
4.80
17.82
9.3
2.7
—
—
—
0
0
83
350
4.79
17.23
12.2
3.3
82.8
52.4
e6/l
0.18
74
248
79
331
4.53
16.30
8.4
5.0
—
—
—
0
0
25
39
7.70
16.02
1.5
1.1
—
—
—
0
0
26
43
7.31
15.81
1.3
2.6
—
—
—
0
0
25
41
7.31
15.30
10.7
3.7
—
—
—
0
0
67
262
4.21
14.90
17.3
4.2
7.4
7.4
ph
0.92
15
45
98
527
4.49
13.34
9.3
5.3
0.0
0.0
e9/l
0.27
93
472
98
552
4.15
11.89
9.4
5.3
1.9
2.0
e9/l
0.45
92
501
16
23
7.79
10.83
3.1
1.2
124.6
100.6
u/ml
—
7
7
59
252
3.46
10.80
7.2
4.4
—
—
—
0
0
72
355
3.30
10.30
9.1
6.8
1.3
1.2
inr
0.27
18
110
9
0
+∞
9.48
6.7
0.0
—
—
—
0
0
16
27
6.62
9.37
2.9
1.3
—
—
—
0
0
23
56
4.78
9.16
10.0
4.1
118.8
128.7
g/l
0.93
23
56
16
28
6.38
9.04
1.4
1.3
154.8
195.1
u/ml
0.65
11
16
54
239
3.15
9.03
3.0
1.8
—
—
—
0
0
13
18
7.91
9.02
1.4
1.7
—
—
—
0
0
38
137
3.51
8.87
2.7
2.7
—
—
—
0
0
88
518
3.16
8.79
9.2
3.3
0.0
0.0
estimate
0.00
21
99
107
708
3.89
8.76
13.0
3.8
—
—
—
0
0
12
16
8.16
8.56
1.8
1.4
—
—
—
0
0
28
84
3.97
8.52
8.6
3.6
—
—
—
0
0
88
525
3.09
8.45
9.5
3.3
0.0
0.0
estimate
0.00
23
95
87
516
3.07
8.44
12.6
4.4
0.0
0.0
estimate
0.00
23
100
98
634
3.22
7.91
10.5
8.5
5.2
4.1
e9/l
4.95
93
557
24
69
4.04
7.70
8.5
6.6
23.3
25.1
mmol/l
1.76
24
69
11
15
7.92
7.67
7.2
2.3
82.4
76.4
%
0.82
11
15
12
9
14.52
7.55
11.7
3.3
—
—
—
0
0
42
183
2.91
6.98
3.4
1.6
—
—
—
0
0
9
5
19.16
6.36
1.1
7.2
—
—
—
0
0
6
0
+∞
6.29
1.0
0.0
—
—
—
0
0
11
19
6.23
6.22
8.3
2.4
—
—
—
0
0
30
116
3.06
6.08
1.5
1.5
—
—
—
0
0
88
583
2.58
5.98
8.9
5.7
6.6
6.5
mmol/l
0.02
83
535
81
517
2.50
5.96
5.4
6.4
11.6
10.6
umol/l
0.13
75
496
55
295
2.50
5.91
3.1
2.2
—
—
—
0
0
11
20
5.92
5.91
7.0
4.1
—
—
—
0
0
10
9
11.91
5.90
1.4
1.4
—
—
—
0
0
17
46
4.10
5.86
11.6
4.1
23.8
24.4
mmol/l
0.34
17
46
73
454
2.39
5.56
16.0
8.2
0.0
0.0
e9/l
0.62
58
367
17
48
3.92
5.54
8.6
2.7
1.1
1.3
%
0.59
17
48
124
1045
5.04
5.42
42.6
14.3
139.0
139.6
mmol/l
1.79
124
1017
5
0
+∞
5.24
11.6
0.0
5.5
—
mmol/l
—
5
0
124
1053
4.84
5.24
43.6
14.3
4.1
4.0
mmol/l
2.50
124
1022
8
6
14.08
5.15
1.5
6.5
—
—
—
0
0
52
288
2.34
5.06
8.0
3.0
—
—
—
0
0
49
266
2.35
4.98
9.1
6.2
—
—
—
0
0
48
262
2.32
4.79
5.0
2.5
—
—
—
0
0
102
769
2.52
4.59
6.9
3.6
19.6
10.1
mm/h
5.38
96
710
19
66
3.20
4.56
3.9
11.8
—
—
—
0
0
25
104
2.74
4.39
7.6
13.1
12.6
11.8
kpa
0.20
25
98
25
104
2.74
4.39
7.7
13.1
4.7
5.0
kpa
0.77
25
96
26
111
2.68
4.34
2.6
1.8
—
—
—
0
0
7
6
12.23
4.32
1.0
1.2
—
—
—
0
0
14
41
3.71
4.32
2.4
1.6
—
—
—
0
0
43
233
2.26
4.30
3.3
2.0
2.6
2.9
mg/l
0.64
38
195
47
265
2.21
4.27
1.6
1.3
3.3
2.3
g/l
3.86
38
158
23
95
2.73
4.08
7.9
14.2
96.1
96.0
%
0.03
23
90
17
59
3.16
4.08
1.6
1.3
—
—
—
0
0
49
290
2.11
3.88
10.0
3.7
0.0
0.0
estimate
0.49
17
94
24
104
2.60
3.88
7.9
13.4
-1.5
1.1
mmol/l
1.18
16
78
43
243
2.15
3.83
8.5
3.3
—
—
—
0
0
53
327
2.05
3.73
2.2
1.9
88.7
92.2
pmol/l
0.20
30
175
18
69
2.87
3.65
18.6
3.7
1.2
1.2
mmol/l
0.84
18
58
20
82
2.70
3.59
2.1
2.9
0.2
0.2
g/l
1.32
20
75
123
1083
3.52
3.48
34.5
12.8
22.8
23.6
mg/l
0.11
117
828
51
317
2.00
3.47
3.6
2.4
—
—
—
0
0
18
71
2.78
3.47
3.3
4.1
0.1
0.1
%
—
7
25
11
32
3.66
3.41
3.2
2.2
—
—
—
0
0
19
78
2.68
3.40
3.2
3.9
0.4
0.7
%
—
7
28
8
15
5.60
3.24
1.0
1.4
—
—
—
0
0
7
11
6.65
3.23
4.3
3.6
—
—
—
0
0
17
68
2.73
3.19
3.1
4.1
0.0
0.4
%
—
6
21
17
68
2.73
3.19
16.7
4.2
—
—
—
0
0
9
20
4.75
3.17
8.9
2.3
5.2
5.1
kpa
—
9
20
41
243
2.00
3.15
7.0
4.6
—
—
—
0
0
5
5
10.32
3.00
1.4
1.2
—
—
—
0
0
8
17
4.94
2.97
1.0
1.5
—
—
—
0
0
8
17
4.94
2.97
1.0
1.5
—
—
—
0
0
8
17
4.94
2.97
2.0
2.7
—
—
—
0
0
8
17
4.94
2.97
1.0
1.5
—
—
—
0
0
8
17
4.94
2.97
1.0
1.5
—
—
—
0
0
7
13
5.62
2.91
7.9
3.4
54.9
54.9
%
—
7
13
7
13
5.62
2.91
4.6
2.2
11.9
13.7
%
—
7
13
7
13
5.62
2.91
7.6
3.2
4.3
3.5
e9/l
—
7
13
125
1135
3.63
2.81
35.5
11.2
—
—
—
0
0
11
38
3.07
2.65
1.7
1.7
21.5
20.3
s
0.33
11
33
7
15
4.87
2.63
2.3
1.1
—
—
—
0
0
9
25
3.79
2.63
10.6
2.3
7.4
7.4
ph
—
9
20
12
44
2.90
2.62
12.0
21.1
—
—
—
0
0
8
20
4.19
2.61
9.9
2.3
9.5
9.0
kpa
—
8
20
8
20
4.19
2.61
1.1
1.0
—
—
—
0
0
108
918
2.04
2.44
8.9
5.0
39.9
39.1
mmol/mol
0.34
101
860
27
151
1.99
2.39
2.4
1.6
1347.3
1243.1
nmol/l
0.24
21
113
18
87
2.24
2.30
11.1
3.3
—
—
—
0
0
5
9
5.72
2.23
1.4
1.2
658.3
110.8
iu/ml
—
5
9
9
31
3.04
2.12
4.3
2.8
—
—
—
0
0
5
10
5.15
2.09
1.2
1.0
—
—
—
0
0
15
70
2.29
2.07
1.5
1.2
—
—
—
0
0
15
71
2.26
2.01
3.1
3.8
0.2
0.4
%
—
5
19
6
16
3.88
1.96
1.2
1.4
—
—
—
0
0
22
123
1.95
1.95
1.0
1.2
—
—
—
0
0
7
22
3.30
1.91
1.0
1.1
—
—
—
0
0
109
955
1.88
1.88
6.0
3.6
1.5
1.3
mmol/l
1.08
103
884
6
147
0.38
1.78
1.2
1.4
—
—
—
0
0
112
995
1.91
1.77
6.5
3.9
1.3
1.4
mmol/l
1.90
106
923
10
42
2.50
1.72
6.5
4.6
—
—
—
0
0
112
998
1.88
1.71
6.6
3.9
4.6
4.6
mmol/l
0.15
106
931
10
43
2.44
1.65
10.6
3.4
—
—
—
0
0
49
362
1.57
1.63
4.4
3.6
41.4
35.4
ng/l
0.17
42
214
30
196
1.69
1.62
1.8
1.5
17.0
21.3
nmol/l
1.00
30
167
6
20
3.09
1.60
2.5
1.9
—
—
—
0
0
14
72
2.06
1.55
1.4
1.3
—
—
—
0
0
19
110
1.85
1.53
1.9
1.6
—
—
—
0
0
9
37
2.54
1.51
1.4
1.2
—
—
—
0
0
33
226
1.62
1.49
2.1
1.8
0.9
1.3
mg/l
0.50
26
180
6
22
2.81
1.45
5.5
4.4
—
—
—
0
0
27
177
1.66
1.44
4.5
2.8
627.0
308.5
ng/l
0.21
19
116
26
172
1.64
1.34
1.1
1.3
18.4
31.4
iu/ml
—
6
51
6
25
2.47
1.26
1.0
1.1
—
—
—
0
0
31
220
1.54
1.20
5.1
3.6
—
—
—
0
0
7
32
2.25
1.10
1.4
1.3
—
—
—
0
0
18
114
1.67
1.09
1.3
1.2
—
—
—
0
0
79
685
1.39
1.02
3.6
3.2
—
—
—
0
0
111
1026
1.56
0.98
33.1
12.7
38.1
40.6
%
2.26
81
816
41
322
1.40
0.95
1.6
1.5
—
—
—
0
0
23
162
1.51
0.92
1.4
1.5
—
—
—
0
0
11
64
1.79
0.89
4.3
2.1
—
—
—
0
0
106
977
1.46
0.88
6.7
3.9
5.8
5.8
mmol/l
0.08
98
897
7
39
1.84
0.74
2.6
2.1
—
—
—
0
0
46
387
1.29
0.66
2.1
1.9
—
—
—
0
0
8
49
1.67
0.63
1.0
1.1
—
—
—
0
0
24
186
1.36
0.60
2.7
1.9
—
—
—
0
0
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
15
108
1.44
0.56
1.4
1.4
—
—
—
0
0
11
78
1.45
0.44
2.1
2.5
—
7.7
—
0
5
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
5
36
1.40
0.38
16.6
15.1
—
—
—
0
0
10
73
1.40
0.35
1.3
1.3
—
20.1
—
0
5
43
385
1.17
0.33
3.5
2.5
—
—
—
0
0
33
290
1.18
0.31
1.3
1.3
0.9
1.3
u/ml
—
10
79
9
73
1.25
0.26
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
10.2
—
1220.8
—
0
10
0
10
0.00
0.21
0.0
8.2
—
751.4
—
0
10
0
10
0.00
0.21
0.0
10.0
—
0.6
—
0
10
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
9
111
0.80
0.21
1.2
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
2.3
—
3.6
—
0
13
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
5
70
0.70
0.17
1.2
1.4
—
—
—
0
0
6
53
1.14
0.09
1.2
1.3
—
—
—
0
0
13
117
1.12
0.08
2.3
2.0
—
—
—
0
0
5
62
0.80
0.08
1.0
1.0
—
—
—
0
0
82
805
1.05
0.06
3.8
3.6
14.9
14.6
pmol/l
0.59
73
733
96
972
0.95
0.05
42.7
16.0
331.5
333.9
g/l
1.80
96
966
19
194
0.98
0.00
2.5
2.8
0.7
0.7
ug/l
0.07
13
115
11
107
1.03
0.00
1.3
1.3
—
—
—
0
0
7
75
0.93
0.00
1.1
1.4
—
—
—
0
0
7
75
0.93
0.00
1.1
1.4
—
—
—
0
0
7
73
0.96
0.00
1.1
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
1.2
—
0
6
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
24.6
—
0
6
0
7
0.00
0.00
0.0
8.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
6.0
—
2.4
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
127.0
—
0
6
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
5.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
7
74
0.94
0.00
1.1
1.4
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint N14_HENOCHSCHONLEIN_NEPHRITIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_HENOCHSCHONLEIN_NEPHRITIS 2.718 [1.97, 3.75] < 0.001
Birth year 0.982 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 588 males with N14_HENOCHSCHONLEIN_NEPHRITIS died.

Mortality risk

Mortality risk for people of age

years, who have N14_HENOCHSCHONLEIN_NEPHRITIS.

N-year risk Females Males
1 No data 0.508%
5 No data 2.64%
10 No data 6.883%
15 No data 12.352%
20 No data 20.208%

Relationships between endpoints

↥

Index endpoint: N14_HENOCHSCHONLEIN_NEPHRITIS – Henoch-Schönlein purpura nephritis (HSPN)

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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