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Henoch-Schönlein purpura nephritis (HSPN)

Endpoint Browser PheWeb

N14_HENOCHSCHONLEIN_NEPHRITIS

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

138

4. Check minimum number of events

None

138

5. Include endpoints

None

138

6. Filter based on genotype QC (FinnGen only)

133

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF7

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 1118 469 646
Only index persons 1031 442 589
Unadjusted period prevalence (%)
Whole population 0.02 0.01 0.02
Only index persons 0.02 0.02 0.02
Median age at first event (years)
Whole population 22.53 20.27 24.01
Only index persons 23.01 21.65 24.04

-FinnGen-

Key figures

All Female Male
Number of individuals 133 68 65
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 44.05 34.99 53.53

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
138
Matched controls
1380
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
N08.2*D69.0
ICD-10 Finland
Glomerular disorders in Henoch(-Schönlein) purpura
+∞
185.8
133
*
D69.0
ICD-10 Finland
Allergic purpura
447.4
96.0
86
5
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
1128.8
70.6
63
*
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
+∞
51.3
46
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
170.4
46.0
46
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
12.9
39.2
45
50
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
+∞
32.6
30
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.0
28.2
49
89
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
+∞
27.0
25
*
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
11.3
25.7
30
33
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
42.0
24.6
30
9
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
52.9
22.3
26
6
C03CA01
ATC
furosemide; systemic
5.6
21.7
61
172
205
Kela drug reimbursment
Chronic hypertension
5.7
21.2
55
144
GD1AA
NOMESCO Finland
Thorax X-ray examination
5.4
20.7
92
374
N18.8
ICD-10 Finland
Other chronic renal failure
35.1
20.5
26
9
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
47.9
20.3
24
6
R31
ICD-10 Finland
Unspecified haematuria
7.4
19.8
33
56
H02AB06
ATC
prednisolone; systemic
5.4
19.7
97
423
L04AA06
ATC
mycophenolic acid; systemic
64.8
19.6
22
*
KA1AE
NOMESCO Finland
Kidney ultrasound examination
30.1
19.0
25
10
TK800
NOMESCO Finland
Hemodialysis
30.1
19.0
25
10
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
9.2
18.0
24
31
A12AA04
ATC
calcium carbonate; oral
49.1
17.9
21
5
A11CC03
ATC
alfacalcidol; systemic
37.0
17.7
22
7
Z94.0
ICD-10 Finland
Kidney transplant status
72.8
17.2
19
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
16.6
16.3
26
19
M10.9
ICD-10 Finland
Gout, unspecified
8.1
16.3
24
35
Z49.1
ICD-10 Finland
Extracorporeal dialysis
38.6
16.2
20
6
B03XA02
ATC
darbepoetin alfa; parenteral
68.4
16.2
18
*
127
Kela drug reimbursment
Transplant complication
51.3
15.5
18
*
H02AB04
ATC
methylprednisolone; systemic
5.4
15.2
36
85
M36.4*D69.0
ICD-10 Finland
Arthropathy in Henoch(-Schönlein) purpura
+∞
14.8
14
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.9
13.4
60
229
L04AA01
ATC
[U] ciclosporin
77.2
12.8
14
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.6
12.5
36
99
L04AD01
ATC
ciclosporin; systemic
51.5
12.1
14
*
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
51.5
12.1
14
*
C09AA02
ATC
enalapril; systemic
4.1
11.9
42
134
137
Kela drug reimbursment
Uraemia requiring dialysis
71.2
11.8
13
*
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
71.2
11.8
13
*
V03AE02
ATC
sevelamer; oral
130.4
11.6
12
*
V03AE01
ATC
polystyrene sulfonate; oral
38.6
11.5
14
*
L04AX01
ATC
azathioprine; systemic
12.8
11.5
20
18
C09CA01
ATC
losartan; oral
3.7
11.4
50
185
M04AA01
ATC
allopurinol; systemic
4.7
11.3
30
77
L95.8
ICD-10 Finland
Other vasculitis limited to skin
65.2
10.8
12
*
Z49.2
ICD-10 Finland
Other dialysis
118.7
10.6
11
*
B05DA
ATC
Isotonic solutions
118.7
10.6
11
*
C08CA01
ATC
amlodipine; oral
3.3
10.3
61
270
L04AD02
ATC
tacrolimus; systemic
43.5
10.1
12
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
43.5
10.1
12
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
43.5
10.1
12
*
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
59.3
9.8
11
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
32.6
9.6
12
*
B03XA01
ATC
erythropoietin; parenteral
107.1
9.5
10
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
107.1
9.5
10
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
9.2
48
195
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
53.5
8.8
10
*
B05DB
ATC
Hypertonic solutions
95.7
8.5
9
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
95.7
8.5
9
*
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
95.7
8.5
9
*
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.0
8.5
27
79
N17.9
ICD-10 Finland
Acute renal failure, unspecified
9.9
8.3
16
18
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
18.6
8.2
12
7
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.1
8.2
43
174
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.8
8.1
18
26
TK820
NOMESCO Finland
Peritoneal dialysis
47.7
7.8
9
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.8
7.7
26
79
C08CA02
ATC
felodipine; oral
4.9
7.7
18
41
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.1
7.4
22
61
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
+∞
7.4
7
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
+∞
7.4
7
*
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
31.8
7.2
9
*
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.5
6.7
15
22
C07AG02
ATC
carvedilol; oral
6.3
6.7
17
30
SPAT1262
SPAT
Handing over of treatment supplies
3.3
6.7
29
104
UJF32
NOMESCO Finland
Coloscopy
2.9
6.6
39
167
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
73.1
6.5
7
*
H05BX01
ATC
cinacalcet; oral
28.1
6.3
8
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
28.1
6.3
8
*
C02AC05
ATC
moxonidine; oral
8.3
6.3
13
17
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
9.3
6.2
12
14
C07AB02
ATC
metoprolol; systemic
3.0
6.2
31
121
Z2446
NOMESCO Finland
Social worker
4.1
6.1
18
49

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
90
129
18.18
69.25
16.9
6.5
1.21
1.07
mmol/l
2.57
85
116
100
257
11.50
44.51
8.6
3.1
212.50
80.50
mg/l
2.27
95
165
37
33
14.95
36.95
9.4
3.1
0.42
0.26
g/l
0.58
26
16
55
122
6.83
25.92
7.1
2.2
24.01
22.93
%
0.21
47
105
56
141
6.00
22.76
1.6
1.4
767.27
371.25
titre
0.41
11
32
105
468
6.20
21.32
24.4
7.9
1.21
1.21
mmol/l
0.08
90
394
30
42
8.85
21.27
1.6
1.1
—
—
—
0
0
85
322
5.27
20.99
10.6
2.9
60.41
230.06
e6/l
0.41
76
253
45
99
6.26
20.97
11.3
3.7
1.15
1.65
mmol/l
0.51
39
77
79
292
4.99
19.86
10.1
2.7
0.12
0.36
e6/l
2.11
70
222
77
290
4.74
18.63
9.3
2.7
—
—
—
0
0
39
85
6.00
18.16
13.3
9.7
—
—
—
0
0
87
371
4.64
17.58
12.1
3.3
79.82
53.02
e6/l
0.16
77
262
72
280
4.29
16.19
16.4
4.3
7.39
7.40
ph
0.64
16
46
27
47
6.90
15.61
1.3
2.4
—
—
—
0
0
48
148
4.44
14.56
7.3
2.4
3.84
2.15
e6/l
0.37
35
79
99
516
4.25
14.02
10.3
5.7
—
—
—
0
0
25
45
6.56
13.94
10.7
3.5
—
—
—
0
0
63
267
3.50
11.70
6.8
4.4
—
—
—
0
0
85
448
3.34
10.81
7.4
3.1
5.44
5.77
ph
—
8
33
96
548
3.47
10.61
8.8
3.3
0.00
0.01
estimate
0.50
26
111
96
551
3.44
10.45
9.0
3.4
0.00
0.00
estimate
-0.00
25
101
95
542
3.42
10.44
12.1
4.4
0.00
0.00
estimate
-0.00
25
106
42
147
3.67
10.32
2.8
2.6
—
—
—
0
0
115
748
4.22
10.09
12.6
3.8
—
—
—
0
0
9
0
+∞
9.48
6.7
0.0
—
—
—
0
0
81
440
3.04
9.33
14.7
9.8
1.40
1.18
inr
0.87
22
129
56
251
3.07
9.06
2.9
1.8
—
—
—
0
0
14
10
15.40
8.91
10.2
3.6
—
—
—
0
0
104
671
3.23
8.44
10.5
8.6
5.28
4.12
e9/l
5.14
98
587
25
73
3.96
7.83
8.2
6.5
23.37
25.05
mmol/l
1.58
25
73
28
89
3.69
7.78
8.5
3.4
—
—
—
0
0
44
189
2.95
7.49
3.3
1.6
—
—
—
0
0
16
23
7.72
7.24
3.1
1.2
124.57
100.57
u/ml
—
7
7
14
19
8.06
6.60
1.4
1.7
—
—
—
0
0
16
27
6.56
6.53
2.9
1.3
—
—
—
0
0
94
620
2.62
6.50
8.5
5.7
6.50
6.55
mmol/l
0.11
89
568
13
16
8.84
6.50
1.8
1.4
—
—
—
0
0
11
10
11.82
6.42
1.4
1.4
—
—
—
0
0
57
300
2.53
6.38
7.8
3.0
—
—
—
0
0
9
5
19.09
6.35
1.1
7.2
—
—
—
0
0
18
48
4.16
6.32
8.1
2.7
0.63
0.66
%
0.18
18
48
86
549
2.50
6.30
5.2
6.3
11.25
10.63
umol/l
0.09
80
527
6
0
+∞
6.29
1.0
0.0
—
—
—
0
0
31
120
3.04
6.25
1.5
1.5
—
—
—
0
0
16
29
6.10
6.22
1.5
1.2
154.82
195.12
u/ml
0.65
11
16
132
1106
5.45
6.12
41.3
14.4
139.05
139.64
mmol/l
1.90
132
1076
18
50
3.99
5.99
8.2
2.7
1.05
1.29
%
0.73
18
50
132
1114
5.25
5.93
42.1
14.4
4.05
3.96
mmol/l
2.35
132
1081
77
478
2.38
5.86
16.5
8.3
0.00
0.00
e9/l
0.62
62
384
17
36
5.24
5.85
2.4
2.2
281.65
481.88
ug/l
0.46
17
31
57
316
2.37
5.55
3.1
2.2
—
—
—
0
0
52
283
2.34
5.23
1.7
1.3
3.38
2.32
g/l
4.68
42
167
8
6
14.04
5.14
1.5
6.5
—
—
—
0
0
109
816
2.60
5.10
6.9
3.6
19.26
10.17
mm/h
5.50
103
750
11
16
7.36
5.06
7.2
2.5
82.43
75.35
%
1.04
11
16
12
20
6.46
5.04
7.7
2.3
—
—
—
0
0
54
303
2.29
5.03
9.3
3.7
0.00
0.01
estimate
0.50
19
99
21
73
3.21
5.02
4.7
4.6
0.13
0.17
%
—
8
29
21
73
3.21
5.02
16.2
3.6
1.21
1.22
mmol/l
0.34
21
61
22
81
3.04
4.78
4.5
4.4
0.50
0.83
%
—
8
38
15
43
3.79
4.76
2.3
1.6
—
—
—
0
0
20
70
3.17
4.73
4.6
4.7
0.00
0.35
%
—
7
26
46
247
2.29
4.70
3.2
1.9
2.49
2.86
mg/l
0.85
41
207
51
286
2.24
4.70
8.9
6.2
—
—
—
0
0
28
122
2.62
4.47
2.5
1.8
—
—
—
0
0
29
129
2.58
4.45
11.7
8.0
103.03
104.64
mmol/l
0.83
29
129
19
67
3.13
4.43
3.9
11.7
—
—
—
0
0
50
286
2.17
4.34
4.9
2.5
—
—
—
0
0
7
6
12.19
4.32
1.0
1.2
—
—
—
0
0
131
1142
3.90
4.29
33.8
12.8
22.12
23.61
mg/l
0.24
125
873
11
22
5.34
4.10
7.0
3.7
—
—
—
0
0
25
109
2.58
3.98
7.6
13.1
12.56
11.85
kpa
0.19
25
103
25
109
2.58
3.98
7.7
13.1
4.70
5.04
kpa
0.83
25
101
17
61
3.04
3.85
1.6
1.3
—
—
—
0
0
19
73
2.86
3.83
15.3
4.0
—
—
—
0
0
56
348
2.03
3.83
2.1
1.9
89.68
92.20
pmol/l
0.15
32
185
45
259
2.09
3.77
8.2
3.3
—
—
—
0
0
21
86
2.70
3.77
2.0
2.8
0.19
0.23
g/l
1.40
21
79
23
100
2.56
3.67
7.9
14.2
96.07
95.98
%
0.03
23
95
24
109
2.45
3.50
7.9
13.4
-1.48
1.03
mmol/l
1.14
16
83
133
1198
4.04
3.44
34.2
11.1
—
—
—
0
0
8
14
5.99
3.39
3.9
3.1
—
—
—
0
0
18
73
2.69
3.28
4.8
4.3
0.17
0.45
%
—
6
30
8
15
5.59
3.24
1.0
1.4
—
—
—
0
0
53
343
1.89
3.10
3.5
2.3
—
—
—
0
0
8
16
5.24
3.10
2.1
1.1
—
—
—
0
0
9
21
4.51
3.05
8.9
2.2
5.19
5.07
kpa
—
9
21
20
90
2.43
2.97
10.4
3.5
—
—
—
0
0
8
17
4.92
2.96
2.0
2.7
—
—
—
0
0
7
13
5.61
2.90
4.6
2.2
11.87
13.72
%
—
7
13
116
978
2.17
2.85
8.7
5.0
39.65
38.96
mmol/mol
0.29
109
917
11
34
3.42
2.80
3.2
2.2
—
—
—
0
0
5
6
8.58
2.77
1.4
1.2
—
—
—
0
0
5
6
8.58
2.77
1.0
1.0
2763.00
1859.83
miu/ml
—
5
6
7
14
5.20
2.76
7.6
3.1
4.33
3.94
e9/l
—
7
14
7
14
5.20
2.76
7.9
4.4
54.86
57.14
%
—
7
14
29
158
2.06
2.75
2.3
1.6
1263.43
1221.47
nmol/l
0.09
23
120
12
41
3.11
2.70
1.8
1.7
21.50
20.40
s
0.30
12
35
8
20
4.18
2.61
1.1
1.0
—
—
—
0
0
9
26
3.63
2.53
10.6
2.2
7.39
7.42
ph
—
9
21
9
26
3.63
2.53
4.0
1.7
—
—
—
0
0
8
21
3.98
2.50
9.9
2.2
9.51
8.92
kpa
—
8
21
6
12
5.17
2.43
1.2
1.0
—
—
—
0
0
24
128
2.06
2.40
1.0
1.2
—
—
—
0
0
12
47
2.70
2.34
12.0
20.2
—
—
—
0
0
10
34
3.09
2.33
3.9
2.6
—
—
—
0
0
54
378
1.70
2.31
4.2
3.6
40.00
36.61
ng/l
0.09
44
227
5
9
5.71
2.23
1.4
1.2
658.34
110.78
iu/ml
—
5
9
6
157
0.35
2.05
1.2
1.4
—
—
—
0
0
119
1052
1.95
1.98
6.4
3.9
1.34
1.42
mmol/l
1.63
113
976
30
185
1.79
1.97
1.1
1.3
26.93
29.85
iu/ml
—
7
55
5
11
4.67
1.96
4.2
5.1
—
—
—
0
0
6
16
3.87
1.95
1.2
1.4
—
—
—
0
0
15
72
2.22
1.94
1.5
1.2
—
—
—
0
0
33
211
1.74
1.92
1.8
1.5
16.43
21.21
nmol/l
1.29
33
179
7
22
3.29
1.90
1.0
1.1
—
—
—
0
0
11
46
2.51
1.90
10.0
3.4
—
—
—
0
0
119
1056
1.92
1.90
6.5
3.9
4.59
4.61
mmol/l
0.07
113
985
115
1011
1.82
1.88
6.0
3.6
1.49
1.29
mmol/l
1.19
109
934
7
24
3.02
1.74
5.0
4.2
—
—
—
0
0
15
77
2.06
1.66
1.7
1.3
—
—
—
0
0
35
237
1.64
1.64
2.1
1.8
0.84
1.39
mg/l
0.74
28
188
10
43
2.43
1.62
6.5
4.7
—
—
—
0
0
18
100
1.92
1.62
2.4
3.0
49.44
29.18
u/l
1.19
18
88
8
33
2.51
1.56
1.4
1.3
—
—
—
0
0
86
723
1.50
1.49
3.5
3.2
—
—
—
0
0
37
260
1.58
1.49
9.6
3.6
1.02
1.02
kg/l
—
5
33
34
235
1.59
1.46
5.0
3.6
—
—
—
0
0
9
40
2.34
1.43
1.4
1.2
—
—
—
0
0
13
69
1.98
1.33
4.3
2.1
—
—
—
0
0
19
116
1.74
1.29
1.9
1.6
—
—
—
0
0
114
1031
1.61
1.29
6.6
3.9
5.82
5.83
mmol/l
0.03
106
944
6
25
2.46
1.25
1.0
1.1
—
—
—
0
0
28
192
1.57
1.24
4.4
2.9
595.85
292.92
ng/l
0.21
20
127
112
1024
1.50
1.04
4.4
4.3
1.93
1.82
mu/l
0.65
107
937
18
119
1.59
0.94
1.3
1.2
—
—
—
0
0
24
174
1.46
0.84
1.4
1.5
—
—
—
0
0
42
340
1.34
0.79
1.6
1.6
—
—
—
0
0
26
196
1.40
0.75
2.5
1.8
—
—
—
0
0
17
118
1.50
0.73
1.4
1.4
—
—
—
0
0
7
40
1.79
0.72
2.6
2.1
—
—
—
0
0
12
78
1.59
0.68
1.2
1.3
—
52.08
—
0
6
8
50
1.64
0.62
1.0
1.1
—
—
—
0
0
0
23
0.00
0.59
0.0
1.4
—
—
—
0
0
12
83
1.49
0.54
2.1
2.5
—
7.68
—
0
5
37
311
1.26
0.52
1.2
1.3
0.92
1.23
u/ml
—
10
83
47
410
1.22
0.48
2.2
1.9
—
—
—
0
0
46
402
1.22
0.46
3.3
2.4
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
10
77
1.32
0.27
1.5
1.5
—
—
—
0
0
15
123
1.25
0.26
2.1
2.0
—
—
—
0
0
5
38
1.33
0.23
16.6
14.7
—
—
—
0
0
89
852
1.13
0.23
3.9
3.7
14.90
14.62
pmol/l
0.54
79
776
10
124
0.79
0.22
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
240.36
—
0
11
0
11
0.00
0.21
0.0
10.7
—
1384.36
—
0
11
0
11
0.00
0.21
0.0
8.9
—
837.00
—
0
11
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
2.3
—
3.62
—
0
13
0
13
0.00
0.21
0.0
1.9
—
—
—
0
0
5
66
0.75
0.17
1.0
1.0
—
—
—
0
0
5
67
0.74
0.17
1.0
1.5
—
—
—
0
0
6
76
0.78
0.16
1.2
1.4
—
—
—
0
0
6
56
1.07
0.09
1.2
1.2
—
—
—
0
0
7
81
0.86
0.07
1.1
1.4
—
—
—
0
0
101
1024
0.95
0.06
41.7
16.2
331.94
333.83
g/l
1.27
101
1018
20
201
0.99
0.00
2.4
2.8
0.67
0.73
ug/l
0.14
14
122
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
79
1.01
-0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
9.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
201.93
—
0
5
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
8
81
0.99
-0.00
1.1
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
0.70
—
0
5
0
5
0.00
-0.00
0.0
6.0
—
2.43
—
0
5
11
110
1.00
-0.00
1.3
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
23.14
—
0
7
8
80
1.00
-0.00
1.1
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
5.0
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint N14_HENOCHSCHONLEIN_NEPHRITIS and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_HENOCHSCHONLEIN_NEPHRITIS 2.718 [1.97, 3.75] < 0.001
Birth year 0.982 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 90 out of 588 males with N14_HENOCHSCHONLEIN_NEPHRITIS died.

Mortality risk

Mortality risk for people of age

years, who have N14_HENOCHSCHONLEIN_NEPHRITIS.

N-year risk Females Males
1 No data 0.508%
5 No data 2.64%
10 No data 6.883%
15 No data 12.352%
20 No data 20.208%

Relationships between endpoints

↥

Index endpoint: N14_HENOCHSCHONLEIN_NEPHRITIS – Henoch-Schönlein purpura nephritis (HSPN)

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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