No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1269 |
4. Check minimum number of eventsNone |
1269 |
5. Include endpointsNone |
1269 |
6. Filter based on genotype QC (FinnGen only) |
1218 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H49
- Name in latin
- Paresis/paralysis nervi abducentis
Similar endpoints
↥List of similar endpoints to
Sixth [abducent] nerve palsy
based on the number of shared cases.
Similar with more cases:
- Paralytic strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7973 | 4049 | 3894 |
| Only index persons | 7178 | 3707 | 3471 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.11 |
| Only index persons | 0.13 | 0.14 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 63.91 | 64.87 | 62.88 |
| Only index persons | 63.69 | 64.69 | 62.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1218 | 604 | 614 |
| Unadjusted period prevalence (%) | 0.25 | 0.21 | 0.28 |
| Median age at first event (years) | 62.91 | 61.13 | 64.66 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1269
- Matched controls
- 12690
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
307.7
1269
*
H53.2
ICD-10 Finland
Diplopia
83.3
307.7
575
125
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.8
153.2
342
756
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
6.4
143.4
274
521
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
10.1
113.2
134
146
AA1AD
NOMESCO Finland
CT of head and brain
3.3
91.6
566
2501
XCK00
NOMESCO Finland
Perimetry
5.4
86.2
186
388
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
840.1
81.4
79
*
G35
ICD-10 Finland
Multiple sclerosis
14.3
78.1
72
53
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
76.9
73
*
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
23.0
75.0
55
25
109
Kela drug reimbursment
Multiple sclerosis
20.2
75.0
58
30
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
22.6
67.8
50
23
G51.0
ICD-10 Finland
Bell palsy
8.2
67.0
92
120
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
15.9
66.9
58
38
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.1
66.7
211
594
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
65.2
62
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
649.4
63.4
62
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.1
62.9
344
1370
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.4
54.2
72
90
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
21.1
48.9
37
18
A10AB05
ATC
insulin aspart; parenteral
3.6
47.1
172
529
A10AE04
ATC
insulin glargine; parenteral
3.2
45.0
204
718
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
18.0
43.0
35
20
A10AC01
ATC
insulin (human); parenteral
3.4
42.7
171
557
CE2W4
NOMESCO Finland
Eye movement mapping
151.8
42.0
44
*
TAB00
NOMESCO Finland
Lumbar puncture
4.5
40.6
104
247
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
10.3
37.3
42
42
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
6.4
35.8
60
97
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.5
35.3
130
400
A10AA02, ,
ATC
4.6
34.3
84
192
H50.30
ICD-10 Finland
Intermittent esotropy
+∞
33.5
32
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.8
32.7
182
712
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
6.2
32.7
57
96
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.3
31.0
82
199
A10AB01
ATC
insulin (human); parenteral
4.5
30.4
77
181
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
30.3
199
846
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.2
29.9
62
123
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
7.8
29.4
41
54
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.2
29.4
81
203
A10AA01, ,
ATC
5.1
28.6
61
124
XCK10
NOMESCO Finland
Photography of fundus of eye
2.6
27.7
177
740
B01AC04
ATC
clopidogrel; oral
2.2
27.7
291
1517
CEC00
NOMESCO Finland
Recession of extraocular muscle
276.7
26.8
27
*
T89
ICPC
Diabetes insulin dependent
3.8
26.2
81
221
R51.80
ICD-10 Finland
Headache
2.3
24.8
218
1053
103
Kela drug reimbursment
Diabetes, insulin-treated
1.9
24.6
407
2490
H46
ICD-10 Finland
Optic neuritis
9.6
24.5
29
31
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.0
24.0
110
385
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
6.8
23.5
37
56
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
23.4
109
385
H50.51
ICD-10 Finland
Esophoria
+∞
23.0
22
*
CS494
NOMESCO Finland
Other visual field testing
4.4
22.5
58
138
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
21.9
21
*
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
21.4
361
2205
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
7.7
21.3
30
40
A10AB04
ATC
insulin lispro; parenteral
4.0
21.3
62
162
H36.01
ICD-10 Finland
Diabetic maculopathy
6.2
20.4
35
58
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
8.5
20.2
26
31
L03AX13
ATC
glatiramer acetate; parenteral
29.5
19.7
26
9
PA6AD
NOMESCO Finland
CT of neck arteries
3.9
19.6
58
153
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
8.5
19.3
25
30
E10
ICD-10 Finland
Type 1 diabetes mellitus
5.4
18.8
37
70
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
18.8
18
*
A10AE05
ATC
insulin detemir; parenteral
2.8
18.8
98
368
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
18.7
623
4597
H04AA01
ATC
glucagon; nasal, parenteral
5.0
18.6
40
82
SPAT1262
SPAT
Handing over of treatment supplies
1.9
18.5
256
1456
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
18.0
352
2232
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
18.0
545
3906
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
7.9
17.5
24
31
H02.2
ICD-10 Finland
Lagophthalmos
17.2
17.4
27
16
C10AA05
ATC
atorvastatin; oral
1.7
17.3
563
4098
164
Kela drug reimbursment
Fingolimod
42.6
17.3
21
5
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.4
17.3
62
187
H3600, E103,
ICD-10 Finland
7.6
17.0
24
32
R42
ICD-10 Finland
Dizziness and giddiness
1.8
17.0
311
1929
H3603, E103,
ICD-10 Finland
14.3
16.8
28
20
H50.2
ICD-10 Finland
Vertical strabismus
64.2
16.8
19
*
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.5
16.7
106
439
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
16.7
16
*
H3600, E113,
ICD-10 Finland
5.9
16.7
30
52
L03AB07
ATC
interferon beta-1a; parenteral
15.3
16.7
27
18
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.7
16.4
38
83
353
Kela drug reimbursment
Cladribine and fingolimod
40.6
16.4
20
5
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.1
16.3
71
241
H3601, E103,
ICD-10 Finland
14.7
15.9
26
18
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.4
15.8
39
90
F05
ICPC
Visual disturbance other
3.5
15.6
55
164
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.0
15.5
33
67
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
3.7
15.4
48
132
A10AD01
ATC
insulin (human); parenteral
4.2
15.2
40
97
L04AX07
ATC
dimethyl fumarate; oral
23.7
15.1
21
9
H3601, E113,
ICD-10 Finland
4.4
14.8
37
86
N86
ICPC
Multiple sclerosis
16.7
14.8
23
14
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4.2
14.7
39
95
S06.2
ICD-10 Finland
Diffuse brain injury
6.7
14.5
23
35
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.3
14.5
117
541
T90
ICPC
Diabetes non-insulin dependent
1.7
14.5
324
2117
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
4.4
14.4
36
84
A10BB01
ATC
glibenclamide; oral
2.9
14.3
69
249
L04AA27
ATC
[U] fingolimod
43.0
14.1
17
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.2
14.0
127
616
C08CA01
ATC
amlodipine; oral
1.6
13.8
515
3815
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
10.6
13.8
26
25
H50.8
ICD-10 Finland
Other specified strabismus
+∞
13.6
13
*
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.3
13.1
23
19
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
9.5
13.0
26
28
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.8
13.0
65
239
H50.9
ICD-10 Finland
Strabismus, unspecified
50.5
12.9
15
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.4
12.7
86
367
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.8
12.6
28
59
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
70.6
12.6
14
*
3785A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Paralytic strabismus
+∞
12.5
12
*
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
12.5
12
*
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
5.3
12.5
25
48
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
12.5
247
1553
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.0
12.4
54
184
N03AX16
ATC
[U] pregabalin
1.7
12.4
291
1917
Z3231
NOMESCO Finland
Registered nurse
1.6
12.3
348
2400
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
9.1
12.3
25
28
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
37.9
12.2
15
*
A10AD05
ATC
insulin aspart; parenteral
3.5
12.2
41
119
A10BA02
ATC
metformin; oral
1.6
12.0
379
2682
CKC12
NOMESCO Finland
Photocoagulation of retina
2.8
12.0
62
232
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.8
12.0
59
215
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
4.9
11.9
26
54
H3603, E113,
ICD-10 Finland
5.9
11.8
21
36
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
5.9
11.8
21
36
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
9.7
11.8
23
24
ZXA10
NOMESCO Finland
Bilateral
1.7
11.7
245
1563
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
5.6
11.7
22
40
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
23.1
11.6
16
7
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.3
11.6
43
133
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
5.1
11.5
24
48
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
11.5
11
*
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.6
11.5
27
60
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.2
11.3
44
140
A10BB12
ATC
glimepiride; oral
2.1
11.2
108
535
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
25.3
11.1
15
6
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.3
11.1
22
42
H52.1
ICD-10 Finland
Myopia
4.9
11.0
24
50
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
4.1
10.7
29
72
C10AA01
ATC
simvastatin; oral
1.5
10.6
554
4343
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.6
10.5
340
2406
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.8
10.3
31
83
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.5
10.3
35
102
H50.52
ICD-10 Finland
Exophoria
19.0
10.3
15
8
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.9
10.3
148
845
N03AX12
ATC
[U] gabapentin; oral
1.7
10.2
202
1264
XA800
NOMESCO Finland
Neuropsychological investigation
2.6
10.1
57
224
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
10.1
10.0
19
19
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
10.1
10.0
19
19
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
10.0
771
6499
ZXD05
NOMESCO Finland
Urgent procedure
1.5
9.9
373
2725
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
9.7
219
1418
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.4
9.7
22
30
SPAT1229
SPAT
Assessment of need for aid
2.0
9.7
105
545
A10AE06
ATC
insulin degludec; parenteral
2.7
9.6
51
194
H25.8
ICD-10 Finland
Other senile cataract
1.8
9.5
148
864
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.8
9.4
28
75
L03AB08
ATC
interferon beta-1b; parenteral
21.9
9.4
13
6
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.3
9.1
72
330
Z3229
NOMESCO Finland
Other healthcare associate professional
1.9
9.1
111
600
S18
ICPC
Laceration/cut
1.4
9.1
554
4437
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
37.0
9.0
11
*
H52.2
ICD-10 Finland
Astigmatism
7.5
8.9
20
27
H47.1
ICD-10 Finland
Papilloedema, unspecified
8.0
8.9
19
24
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.0
8.8
38
129
H16.0
ICD-10 Finland
Corneal ulcer
2.3
8.8
64
283
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
8.7
226
1516
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.7
8.6
176
1109
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
8.6
408
3107
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.6
284
2009
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
4.6
8.6
20
44
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.6
264
1840
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.6
8.6
50
200
G70.0
ICD-10 Finland
Myasthenia gravis
10.1
8.5
16
16
N29
ICPC
Neurological sympt/complt other
3.4
8.5
30
90
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
27.7
8.5
11
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.9
8.5
40
143
C09AA05
ATC
ramipril; oral
1.5
8.4
327
2395
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.0
8.4
35
117
C09AA02
ATC
enalapril; systemic
1.6
8.3
248
1713
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
10.8
8.3
15
14
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.9
8.3
111
619
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.0
8.2
35
118
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
10.1
8.0
15
15
L04AA31
ATC
[U] teriflunomide
22.2
8.0
11
5
H02.4
ICD-10 Finland
Ptosis of eyelid
2.7
7.9
42
160
N07AA02
ATC
pyridostigmine; systemic
7.8
7.9
17
22
ZXC95
NOMESCO Finland
Use of surgical navigator
4.1
7.8
21
52
A28
ICPC
Limited function/disability NOS
1.6
7.8
223
1525
S02.10
ICD-10 Finland
Fracture of base of skull, closed
10.9
7.8
14
13
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
7.8
70
339
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
7.7
195
1296
CBH25
NOMESCO Finland
Tarsorrhaphy
45.3
7.7
9
*
A02BC02
ATC
pantoprazole; systemic
1.4
7.7
806
7017
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
7.6
74
370
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
10.1
7.5
14
14
205
Kela drug reimbursment
Chronic hypertension
1.4
7.5
347
2617
XCH00
NOMESCO Finland
Eye pressure measurement
2.2
7.5
64
303
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
7.5
201
1356
XCW20
NOMESCO Finland
Eye Movement Research, HESS
80.6
7.4
8
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
3.4
7.4
26
78
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
8.4
7.3
15
18
XCW10
NOMESCO Finland
Assessment of vision
3.6
7.3
23
64
H57.1
ICD-10 Finland
Ocular pain
2.5
7.3
44
179
108
Kela drug reimbursment
Myasthenia gravis
10.9
7.3
13
12
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
7.3
197
1329
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
7.3
7
*
G52.8
ICD-10 Finland
Disorders of other specified cranial nerves
+∞
7.3
7
*
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
7.3
7
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.8
7.2
104
593
G91.0
ICD-10 Finland
Communicating hydrocephalus
8.0
7.1
15
19
L28
ICPC
Limited function/disability (L)
1.5
7.1
213
1472
N06AX21
ATC
duloxetine; oral
1.7
7.1
128
781
G63.2
ICD-10 Finland
Diabetic polyneuropathy
8.8
7.1
14
16
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
7.0
337
2557
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
3.9
7.0
20
52
J01DB01
ATC
cefalexin; oral
1.4
6.9
974
8828
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
6.4
6.9
17
27
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.4
6.9
44
184
N06AA09
ATC
amitriptyline; systemic
1.8
6.9
113
670
ZX120
NOMESCO Finland
Intravenous
1.7
6.9
115
686
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
6.9
90
499
H02AB09
ATC
hydrocortisone; systemic
2.8
6.8
33
120
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.0
6.8
68
343
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
11.0
6.8
12
11
WX140
NOMESCO Finland
Parabulbar anesthesy
2.1
6.8
66
330
CKC10
NOMESCO Finland
Local photocoagulation of retina
2.9
6.8
30
104
ZXA05
NOMESCO Finland
Left side
1.4
6.7
295
2198
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
3.3
6.7
24
73
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
6.7
386
3021
G44.2
ICD-10 Finland
Tension-type headache
1.6
6.6
141
897
H26.4
ICD-10 Finland
After-cataract
1.7
6.6
125
771
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.1
6.6
60
292
A10BJ06
ATC
semaglutide; parenteral
2.1
6.6
60
292
AAF00
NOMESCO Finland
Ventriculostomy
5.9
6.6
17
29
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
6.6
121
742
TKC22
NOMESCO Finland
Catheterisation instruction
2.7
6.5
33
123
A10BH01
ATC
sitagliptin; oral
1.7
6.5
122
752
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
2.0
6.5
66
336
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
5.7
6.5
17
30
A46
ICD-10 Finland
Erysipelas
1.6
6.5
175
1181
H50.31
ICD-10 Finland
Intermittent exotropia
70.2
6.4
7
*
D33.3
ICD-10 Finland
Benign neoplasm: Cranial nerves
70.2
6.4
7
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
70.2
6.4
7
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
7.4
6.4
14
19
S06.3
ICD-10 Finland
Focal brain injury
3.8
6.4
19
51
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
6.4
341
2631
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
6.4
383
3015
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
6.0
6.3
16
27
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.6
6.3
173
1171
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
18.1
6.3
9
5
N03AF01
ATC
carbamazepine; oral, rectal
2.0
6.3
64
326
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.3
256
1881
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
6.3
6
*
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
+∞
6.3
6
*
H49.9
ICD-10 Finland
Paralytic strabismus, unspecified
+∞
6.3
6
*
H49.8
ICD-10 Finland
Other paralytic strabismus
+∞
6.3
6
*
A06AD11
ATC
lactulose; oral
1.5
6.3
183
1256
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
7.1
6.2
14
20
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.2
1073
9968
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
3.5
6.2
20
57
G63.2*E11.4
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic polyneuropathy
3.4
6.2
21
62
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.6
6.1
155
1029
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
3.1
6.1
24
78
Z50.1
ICD-10 Finland
Other physical therapy
2.0
6.0
65
338
SPAT1301
SPAT
No procedures
1.4
6.0
358
2808
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
6.0
470
3849
D43.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, supratentorial
6.1
6.0
15
25
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
73
59
13.07
74.92
1.1
1.1
3.52
4.13
nmol/l
0.09
16
14
565
3256
2.33
45.90
2.3
2.2
136.48
233.59
u/l
3.14
545
3074
103
232
4.74
42.95
1.5
1.7
27.37
43.71
e6/l
0.23
83
182
103
232
4.74
42.95
1.5
1.7
467.93
673.77
e6/l
0.15
85
187
49
56
9.06
39.48
1.2
1.0
1.09
1.11
u/l
0.12
27
29
344
1714
2.38
37.85
2.0
2.2
29.06
29.97
s
1.85
330
1663
63
111
5.92
34.52
1.1
1.1
—
—
—
0
0
56
93
6.25
32.56
1.1
1.0
—
—
—
0
0
849
6249
2.08
32.28
6.0
5.0
7.30
6.76
mmol/l
7.49
806
5874
47
66
7.36
31.94
1.1
1.0
—
—
—
0
0
47
70
6.93
30.29
1.2
1.1
43.13
41.11
mg/l
0.09
36
58
56
100
5.81
30.24
1.8
1.6
—
—
—
0
0
45
66
7.03
29.41
1.1
1.1
209.62
255.61
mg/l
1.27
37
56
161
665
2.63
25.79
2.4
2.5
11.47
25.18
au/ml
—
8
43
50
113
4.57
20.70
1.1
1.1
—
—
—
0
0
581
4146
1.74
20.18
4.3
3.9
36.09
51.15
ng/l
0.70
449
3026
682
5171
1.69
18.31
11.9
17.2
1.21
1.31
inr
1.95
186
1503
28
46
6.20
16.43
1.8
2.0
—
—
—
0
0
103
427
2.54
16.23
1.8
1.9
35.95
39.73
u/l
0.99
93
377
640
4877
1.63
16.01
7.5
6.2
1.21
1.21
mmol/l
0.03
581
4444
457
3201
1.67
15.98
3.9
3.3
479.97
313.43
mg/l
0.29
316
2103
686
5324
1.63
15.88
8.4
7.0
1.21
1.21
mmol/l
0.04
577
4536
917
7671
1.70
15.68
4.9
4.1
13.50
12.98
mm/h
0.41
858
7044
473
3391
1.63
14.82
4.6
3.8
10.20
8.27
mg/mmol
0.43
313
2182
835
6922
1.60
13.74
5.9
4.6
800.29
2635.87
e6/l
0.92
14
107
23
19
12.31
13.12
1.0
1.1
—
—
—
0
0
461
3364
1.58
13.01
3.9
3.2
7.37
7.60
mmol/l
0.49
376
2812
22
39
5.72
11.97
1.0
1.1
688.33
115.50
ng/l
—
6
6
591
4618
1.52
11.97
5.0
4.9
35.04
35.17
g/l
0.21
547
4290
19
13
14.81
11.80
1.1
1.0
5.53
6.65
mg/g
0.56
19
13
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
27
59
4.65
11.68
1.2
1.1
—
—
—
0
0
208
1286
1.74
11.06
7.6
7.6
1.16
1.24
mmol/l
0.12
159
1022
22
43
5.19
10.81
1.1
1.2
—
—
—
0
0
39
119
3.35
10.73
1.3
1.7
—
—
—
0
0
370
2660
1.55
10.73
4.7
4.1
90.01
87.29
%
1.44
362
2591
206
1287
1.72
10.52
7.6
7.6
5.13
5.10
kpa
0.18
189
1229
20
20
10.14
10.52
1.2
1.4
—
—
—
0
0
206
1288
1.72
10.49
7.6
7.6
12.69
12.04
kpa
0.84
189
1232
1119
10220
1.80
10.42
20.3
15.4
22.36
25.29
mg/l
2.38
933
8151
161
945
1.81
10.20
3.0
2.2
359.17
375.38
nmol/l
0.50
151
856
139
781
1.88
10.12
3.6
3.0
9.57
10.80
g/l
2.97
126
713
720
5989
1.47
9.97
11.2
9.0
4.55
4.17
e9/l
1.99
632
5225
66
280
2.43
9.94
2.6
2.4
79.16
121.58
ug/min
0.48
39
167
627
5084
1.46
9.88
4.6
3.8
0.03
0.00
estimate
0.42
106
937
24
55
4.43
9.82
1.2
1.1
—
—
—
0
0
35
108
3.30
9.49
1.3
1.7
—
—
—
0
0
611
4959
1.45
9.42
8.5
6.2
25.88
27.22
%
2.18
576
4647
1148
10627
1.84
9.37
24.0
18.0
139.53
139.61
mmol/l
0.51
1122
10337
617
5022
1.44
9.34
6.0
5.1
0.00
0.00
estimate
0.50
114
968
601
4875
1.44
9.23
8.3
6.0
59.17
57.68
%
2.19
565
4572
64
279
2.36
9.10
1.9
2.0
10.26
12.17
mg/l
1.02
59
252
1149
10655
1.83
9.10
24.0
18.2
3.98
3.99
mmol/l
0.37
1118
10349
154
923
1.76
9.07
3.0
2.9
66.14
66.29
g/l
0.08
137
837
917
8073
1.49
8.98
8.9
7.6
82.69
78.96
u/l
0.80
865
7577
616
5042
1.43
8.88
4.6
3.8
0.00
0.00
estimate
0.75
118
1041
319
2314
1.51
8.59
3.1
2.6
3.81
5.50
e6/l
2.69
285
2092
1034
9376
1.56
8.42
5.6
4.7
1.99
2.09
mu/l
0.34
940
8505
876
7706
1.44
8.09
4.6
3.9
15.04
14.89
pmol/l
0.91
786
6966
217
1478
1.56
7.73
6.1
6.0
1.05
1.04
mmol/l
0.21
200
1364
25
71
3.57
7.72
1.8
1.9
—
—
—
0
0
17
23
7.48
7.68
1.1
1.2
—
—
—
0
0
658
5539
1.39
7.61
6.7
6.3
10.58
11.62
umol/l
2.40
634
5255
519
4217
1.39
7.35
2.3
2.2
77.71
77.39
nmol/l
0.08
462
3728
25
74
3.43
7.27
5.2
2.0
18.92
21.86
nmol/l
0.51
25
66
482
3876
1.39
7.23
5.0
4.0
—
—
—
0
0
176
1160
1.60
7.20
8.3
7.9
96.35
95.59
%
2.05
168
1120
17
38
4.52
7.19
1.0
1.1
—
—
—
0
0
14
17
8.31
6.83
1.1
1.2
—
—
—
0
0
12
11
11.00
6.80
1.1
1.4
—
—
—
0
0
161
1054
1.60
6.76
8.7
8.4
119.01
121.34
g/l
0.75
156
1027
1036
9531
1.47
6.56
8.4
6.0
44.41
40.22
mmol/mol
17.54
946
8779
12
12
10.08
6.54
1.2
1.2
—
—
—
0
0
383
3009
1.39
6.44
4.0
3.2
0.22
0.48
e6/l
4.60
313
2329
220
1569
1.49
6.26
2.8
2.5
2.17
2.30
g/l
2.80
203
1457
352
2745
1.39
6.14
5.2
4.1
0.00
0.01
estimate
0.88
114
930
294
2225
1.42
6.10
5.4
4.1
1.02
1.02
kg/l
0.15
47
317
10
8
12.59
6.08
2.1
2.5
—
—
—
0
0
16
29
5.57
6.00
1.0
1.1
—
—
—
0
0
463
3786
1.35
5.97
4.7
3.8
133.41
114.75
e6/l
0.08
351
2749
49
230
2.18
5.95
1.6
1.7
3.26
4.81
iu/l
0.72
21
69
249
1839
1.44
5.90
1.9
1.9
—
—
—
0
0
48
225
2.18
5.85
2.6
1.7
0.68
0.86
nmol/l
1.54
38
184
152
1017
1.56
5.81
6.9
7.7
9.63
10.26
mmol/l
0.54
141
967
408
3288
1.36
5.74
4.2
3.3
46.37
91.83
e6/l
1.16
328
2573
294
2247
1.40
5.73
1.7
1.8
1.49
1.34
mg/l
0.26
231
1726
16
31
5.21
5.71
1.1
1.2
—
—
—
0
0
16
31
5.21
5.71
1.1
1.1
—
—
—
0
0
205
1479
1.46
5.47
2.8
2.6
22.77
22.93
%
0.05
173
1267
112
709
1.64
5.40
9.8
6.7
25.02
24.51
mmol/l
0.90
104
673
529
4462
1.32
5.36
2.1
2.0
95.56
93.81
pmol/l
0.34
251
2329
19
58
3.31
5.31
1.0
1.2
—
—
—
0
0
9
8
11.32
5.29
1.0
1.0
—
—
—
0
0
96
588
1.68
5.26
8.5
10.3
24.25
24.48
mmol/l
0.33
89
572
15
30
5.05
5.26
1.0
1.1
—
—
—
0
0
229
1701
1.42
5.22
2.8
2.5
12.11
12.93
umol/l
0.97
210
1575
57
300
1.94
5.14
1.6
1.5
0.06
23.63
iu/ml
0.49
16
51
25
92
2.75
5.12
2.4
2.3
622.76
650.95
ml
0.17
17
57
234
1751
1.41
5.11
3.5
3.6
0.81
0.82
mmol/l
0.11
218
1642
103
650
1.64
5.04
1.7
1.5
—
—
—
0
0
1144
10869
1.53
4.91
13.6
10.6
26.48
25.95
u/l
0.44
1096
10461
14
29
4.87
4.81
4.6
2.0
—
—
—
0
0
41
196
2.13
4.81
1.4
1.7
—
—
—
0
0
325
2604
1.33
4.59
2.8
2.4
—
—
—
0
0
9
11
8.23
4.56
1.1
1.3
—
—
—
0
0
149
1048
1.48
4.52
4.8
3.9
2.12
2.09
mmol/l
0.04
120
857
8
8
10.05
4.52
1.0
1.3
—
—
—
0
0
63
359
1.79
4.48
3.7
3.9
67.66
71.48
mg/l
0.06
50
287
402
3333
1.30
4.42
3.2
3.2
1548.17
1546.39
ng/l
0.00
346
2869
63
361
1.78
4.40
3.7
3.9
43.70
70.80
mg/l
0.36
51
290
270
2120
1.35
4.35
1.8
1.7
1116.41
1187.23
nmol/l
0.68
212
1600
336
2726
1.32
4.32
1.9
1.6
1.34
1.36
mmol/l
0.18
278
2264
241
1864
1.36
4.28
3.6
2.8
1.32
1.09
e6/l
0.45
145
1094
61
351
1.78
4.21
3.7
3.8
1.66
1.78
ratio
—
5
28
148
1056
1.45
4.18
4.5
3.8
5.79
5.85
kpa
0.32
139
1024
13
30
4.37
4.13
1.2
1.1
—
—
—
0
0
57
325
1.79
4.07
1.7
1.6
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
66
393
1.72
4.06
2.5
3.1
0.38
0.35
u/ml
0.24
27
222
566
4940
1.26
4.04
3.0
2.6
—
—
—
0
0
27
117
2.34
4.03
4.4
2.7
—
—
—
0
0
241
1892
1.34
3.86
1.8
1.5
2.55
2.51
g/l
0.10
154
1134
173
1290
1.39
3.83
1.7
1.8
—
—
—
0
0
175
1308
1.39
3.82
9.8
7.7
—
—
—
0
0
76
479
1.62
3.79
1.7
1.9
3.21
1.97
ug/l
0.27
63
428
23
97
2.40
3.66
1.3
1.5
—
—
—
0
0
23
97
2.40
3.66
1.3
1.5
—
—
—
0
0
23
97
2.40
3.66
1.3
1.5
—
—
—
0
0
11
25
4.43
3.62
2.5
1.9
—
—
—
0
0
125
889
1.45
3.61
4.1
3.2
4.52
4.57
kpa
0.09
114
859
14
40
3.53
3.61
1.0
1.0
1230.00
1573.63
miu/ml
0.61
14
40
140
1017
1.42
3.61
2.6
2.5
6.89
7.18
ug/l
0.04
122
903
110
765
1.48
3.56
3.2
3.9
5.21
5.17
kpa
0.19
104
737
391
3305
1.26
3.56
3.2
2.5
60.11
83.60
u/l
0.46
358
3053
105
724
1.49
3.55
3.3
3.9
1.90
1.73
mmol/l
0.18
77
556
98
668
1.51
3.50
6.8
8.5
24.80
24.80
mmol/l
0.00
98
663
425
3635
1.25
3.48
3.1
3.5
2.35
2.35
mmol/l
0.31
360
3171
51
296
1.75
3.47
1.7
1.3
0.25
0.24
g/l
0.17
46
279
28
132
2.15
3.47
12.1
6.3
8.67
6.92
mmol/l
1.27
23
107
118
838
1.45
3.44
2.9
2.8
62.21
63.86
ml/min/173m2
0.18
52
341
42
730
0.56
3.44
1.4
1.7
—
—
—
0
0
22
94
2.36
3.42
1.1
1.3
—
—
—
0
0
46
261
1.79
3.38
1.5
1.7
—
—
—
0
0
170
1293
1.36
3.35
1.8
1.8
—
—
—
0
0
13
43
3.04
3.25
1.2
1.0
—
—
—
0
0
43
243
1.80
3.22
1.8
2.4
130.57
128.38
g/l
0.22
35
182
7
11
6.39
3.18
1.3
1.4
—
—
—
0
0
260
2119
1.29
3.15
1.4
1.2
1.54
1.46
u/ml
0.04
69
555
282
2322
1.28
3.15
1.7
1.7
441.67
15013555.38
pmol/l
1.30
223
1905
13
44
2.97
3.14
1.5
1.9
86.67
99.54
umol/l
—
6
28
255
2076
1.29
3.11
4.1
4.1
669.63
417.97
ng/l
0.28
212
1689
56
345
1.65
3.10
1.2
1.2
0.36
1.25
u/ml
—
8
26
156
1188
1.36
3.05
3.2
2.9
6.40
8.43
umol/l
1.15
143
1052
8
16
5.02
3.05
1.1
1.1
—
—
—
0
0
331
2792
1.25
3.00
2.4
2.2
3.11
3.08
mg/l
0.09
288
2355
1170
11318
1.43
2.99
30.5
22.6
39.56
39.89
%
0.85
1089
10523
17
69
2.48
2.96
2.8
2.6
—
—
—
0
0
65
422
1.57
2.93
2.4
2.7
4.37
3.63
g/l
0.91
57
377
172
1338
1.33
2.93
4.7
4.6
33.93
32.32
%
1.05
131
907
1170
11323
1.43
2.93
30.4
22.4
248.93
245.70
e9/l
0.89
1146
11002
50
304
1.67
2.93
2.2
2.8
95.74
90.24
%
1.08
50
293
65
423
1.57
2.90
2.4
2.7
—
—
—
0
0
65
423
1.57
2.90
2.4
2.7
7.61
7.40
g/l
0.43
57
377
1170
11326
1.42
2.89
30.3
22.4
7.18
6.78
e9/l
3.46
1140
10968
162
1252
1.34
2.89
5.5
4.1
235.47
248.41
u/l
0.55
153
1185
1170
11327
1.42
2.88
30.3
22.4
4.46
4.46
e12/l
0.07
1141
10970
1170
11329
1.42
2.86
30.4
22.6
133.84
134.77
g/l
1.25
1155
11130
37
208
1.80
2.85
1.8
2.1
6338.56
3443.61
u/l
—
10
80
1014
9642
1.26
2.72
18.5
14.2
78.12
78.58
ml/min/173m2
0.26
865
7974
40
234
1.73
2.71
2.3
1.5
11.71
9.53
u/l
0.37
32
178
714
6562
1.20
2.67
3.6
3.2
60.90
50.32
u/l
1.12
663
6102
33
184
1.81
2.63
1.2
1.6
—
—
—
0
0
7
15
4.69
2.60
5.1
1.3
—
—
—
0
0
75
521
1.47
2.51
5.5
4.3
24.22
24.18
mmol/l
0.04
70
508
52
334
1.58
2.49
1.4
1.3
—
—
—
0
0
11
37
2.99
2.49
1.2
1.3
—
—
—
0
0
111
829
1.37
2.49
4.1
3.8
98.24
90.30
ng/l
0.29
98
716
62
415
1.52
2.48
1.8
1.8
—
—
—
0
0
489
4362
1.20
2.48
3.0
2.8
182.43
139.11
ug/l
1.16
445
3984
40
241
1.68
2.46
1.1
1.1
—
—
—
0
0
8
21
3.83
2.46
1.0
1.4
—
—
—
0
0
162
1294
1.29
2.30
3.9
2.5
1.83
1.80
%
0.18
141
1150
59
398
1.51
2.30
2.5
2.7
10.13
10.70
g/l
0.52
51
351
43
270
1.61
2.28
1.5
1.6
—
—
—
0
0
19
92
2.08
2.27
1.1
1.2
—
—
—
0
0
376
3297
1.20
2.27
3.3
3.3
37.43
33.60
u/l
0.44
355
3127
53
352
1.53
2.23
1.5
1.5
—
140.00
—
0
13
22
115
1.93
2.16
1.2
1.5
—
—
—
0
0
6
14
4.30
2.15
1.0
1.1
—
—
—
0
0
39
245
1.61
2.09
2.6
2.8
16.99
15.81
%
0.97
26
127
5
10
5.01
2.07
1.2
1.1
—
—
—
0
0
28
161
1.76
2.07
1.4
1.6
—
—
—
0
0
66
467
1.44
2.05
5.7
4.9
1.83
1.60
%
0.46
61
440
6
15
4.01
2.04
1.8
2.0
—
—
—
0
0
57
393
1.47
2.03
2.5
2.7
2.98
3.00
g/l
0.05
49
347
211
1767
1.23
2.02
3.9
3.0
2.57
2.04
e6/l
0.35
112
1002
129
1023
1.29
1.96
2.3
2.3
0.21
0.21
g/l
0.22
114
951
43
283
1.54
1.92
2.0
1.5
—
—
—
0
0
75
552
1.38
1.89
3.6
3.2
4.50
4.51
pmol/l
0.03
69
478
921
8778
1.18
1.88
23.8
18.2
15.36
15.10
%
0.60
906
8604
1035
9966
1.21
1.88
5.4
4.7
6.46
6.00
mmol/l
9.86
939
9006
30
182
1.66
1.86
1.5
1.6
—
—
—
0
0
30
182
1.66
1.86
1.5
1.6
—
—
—
0
0
11
46
2.40
1.85
1.5
1.7
—
—
—
0
0
122
970
1.29
1.83
2.7
2.4
45.93
39.59
u/l
0.15
95
820
12
53
2.28
1.81
1.5
2.6
497.50
1545.85
u/ml
1.39
12
53
27
161
1.69
1.79
1.1
1.5
—
—
—
0
0
195
1643
1.22
1.77
1.2
1.3
34.97
36.86
iu/ml
0.05
47
515
65
473
1.39
1.77
3.4
4.4
25.34
24.81
mmol/l
0.84
59
445
314
2767
1.18
1.75
3.5
2.9
2496.97
7214.88
umol/l
1.31
271
2396
5
13
3.86
1.71
10.2
13.7
5.16
5.07
mmol/l
—
5
13
52
366
1.44
1.71
2.7
3.0
2.63
1.37
g/l
0.50
42
314
110
874
1.28
1.68
4.8
4.3
1.22
1.22
mmol/l
0.07
94
759
36
236
1.54
1.66
1.3
1.3
—
—
—
0
0
70
522
1.36
1.66
1.7
1.9
1.66
1.50
g/l
0.57
61
465
17
90
1.90
1.65
5.2
5.1
340.50
40.77
u/ml
—
5
29
1041
10065
1.19
1.62
5.4
4.5
4.39
4.56
mmol/l
5.99
966
9264
1061
10279
1.20
1.59
5.9
5.0
2.51
2.68
mmol/l
7.31
981
9395
1032
9982
1.18
1.54
5.2
4.5
1.41
1.44
mmol/l
1.59
955
9116
102
813
1.28
1.53
1.9
1.7
—
—
—
0
0
12
58
2.08
1.49
2.7
2.5
—
—
—
0
0
296
2630
1.16
1.48
1.6
1.6
20.35
20.51
nmol/l
0.05
253
2206
61
455
1.36
1.47
2.1
1.9
—
—
—
0
0
10
45
2.23
1.46
1.5
1.7
—
—
—
0
0
10
45
2.23
1.46
1.5
1.7
—
—
—
0
0
23
140
1.65
1.45
1.1
1.6
—
—
—
0
0
436
3990
1.14
1.44
5.4
5.2
3.16
3.01
ug/l
0.10
383
3552
98
784
1.27
1.44
2.7
2.2
12.53
12.63
nmol/l
0.04
88
695
5
16
3.13
1.44
2.0
2.6
—
—
—
0
0
16
88
1.83
1.41
1.4
1.3
—
—
—
0
0
20
118
1.71
1.41
1.2
1.0
—
—
—
0
0
24
149
1.62
1.41
1.3
1.6
—
—
—
0
0
21
126
1.68
1.40
1.3
1.6
—
—
—
0
0
21
126
1.68
1.40
1.3
1.6
—
—
—
0
0
7
29
2.42
1.39
1.0
1.3
—
—
—
0
0
20
119
1.69
1.38
1.5
1.8
—
1872.00
—
0
5
5
17
2.95
1.36
1.2
1.1
—
—
—
0
0
5
17
2.95
1.36
2.0
2.5
—
—
—
0
0
14
75
1.88
1.34
1.6
1.3
—
—
—
0
0
14
75
1.88
1.34
1.6
1.3
—
—
—
0
0
236
2077
1.17
1.34
2.8
3.1
2.45
2.45
mmol/l
0.03
198
1824
34
233
1.47
1.32
1.3
1.6
—
—
—
0
0
5
18
2.78
1.28
1.2
3.1
—
—
—
0
0
31
210
1.49
1.28
3.1
3.5
61.32
57.93
%
0.86
31
210
53
397
1.35
1.27
2.0
2.9
—
—
—
0
0
182
1577
1.18
1.26
1.2
1.3
16.86
11.93
u/ml
0.29
66
593
8
36
2.23
1.24
1.9
1.3
—
—
—
0
0
41
296
1.40
1.23
2.0
1.6
—
—
—
0
0
30
204
1.48
1.23
3.2
3.2
4.15
4.36
e9/l
0.23
30
204
87
703
1.26
1.21
1.7
1.6
—
—
—
0
0
996
9660
1.14
1.20
4.8
4.0
1.35
1.29
mmol/l
1.68
908
8765
136
1154
1.20
1.19
3.5
3.5
—
—
—
0
0
34
239
1.43
1.19
6.7
3.9
26.57
28.51
mg/l
0.11
22
151
17
274
0.62
1.19
4.4
3.2
0.72
0.84
nmol/l
0.86
12
217
6
26
2.31
1.18
1.3
1.3
—
—
—
0
0
42
307
1.38
1.18
1.3
1.5
262.11
269.74
ug/g
0.10
28
178
351
3209
1.13
1.16
4.3
4.4
22.62
21.16
%
0.85
163
1600
17
271
0.62
1.14
1.4
1.5
—
—
—
0
0
45
337
1.35
1.11
2.8
2.6
35.87
37.43
g/l
0.90
37
291
41
304
1.36
1.08
2.1
1.6
—
—
—
0
0
11
59
1.87
1.07
7.0
3.6
—
—
—
0
0
7
33
2.13
1.05
2.0
1.3
—
—
—
0
0
7
34
2.06
1.03
1.3
1.2
109.14
110.82
%
—
7
28
618
5863
1.11
1.02
2.8
2.8
—
—
—
0
0
24
165
1.46
0.97
1.5
1.3
—
—
—
0
0
27
191
1.42
0.95
2.3
2.0
1.95
1.66
mmol/l
0.50
27
186
9
51
1.77
0.94
1.0
1.0
—
—
—
0
0
32
234
1.38
0.94
1.3
1.3
—
—
—
0
0
32
234
1.38
0.94
1.3
1.3
—
—
—
0
0
10
55
1.82
0.92
1.4
1.4
—
—
—
0
0
10
55
1.82
0.92
1.1
1.2
—
—
—
0
0
14
86
1.63
0.91
1.6
1.8
3.48
3.86
mg/l
0.20
14
81
110
1276
0.85
0.90
1.4
1.4
—
—
—
0
0
20
135
1.49
0.89
2.1
2.4
25.00
24.74
mg/l
—
6
34
12
71
1.70
0.89
1.2
1.6
11.86
5.71
u/l
—
7
63
21
300
0.69
0.88
1.4
1.4
—
—
—
0
0
7
128
0.54
0.88
1.1
1.6
—
—
—
0
0
10
57
1.76
0.83
1.7
1.6
—
—
—
0
0
10
57
1.76
0.83
1.2
1.5
1.01
1.16
nmol/l
—
5
44
10
57
1.76
0.83
1.7
1.6
—
—
—
0
0
41
320
1.29
0.81
2.3
1.4
25.04
27.18
iu/l
0.17
34
268
10
164
0.61
0.80
1.4
1.5
—
—
—
0
0
8
48
1.67
0.78
3.3
3.9
—
—
—
0
0
74
622
1.20
0.78
1.3
1.2
163.61
153.65
iu/ml
0.08
30
240
14
91
1.54
0.75
1.4
1.7
—
—
—
0
0
33
254
1.31
0.74
8.6
6.6
106.64
105.19
mmol/l
1.02
28
230
9
56
1.61
0.72
1.2
1.7
—
—
—
0
0
5
26
1.93
0.70
2.0
1.7
62.60
101.31
nmol/24h
—
5
26
19
135
1.41
0.69
1.1
1.2
1.63
3.87
u/ml
—
8
45
33
257
1.29
0.69
1.5
1.3
—
—
—
0
0
5
27
1.86
0.68
1.0
1.7
—
—
—
0
0
18
127
1.42
0.68
1.4
1.8
—
—
—
0
0
21
153
1.38
0.67
1.1
1.1
6852.98
27.77
iu/ml
—
5
32
5
28
1.79
0.66
1.0
1.6
15.60
13.76
pmol/l
—
5
21
5
28
1.79
0.66
1.2
1.2
—
—
—
0
0
7
44
1.59
0.65
2.9
2.7
39642.86
39195.57
ug/l
—
7
44
30
234
1.29
0.63
1.2
1.4
—
—
—
0
0
37
298
1.25
0.61
1.4
1.2
—
—
—
0
0
13
187
0.69
0.61
1.5
1.5
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
1.37
—
0
13
37
299
1.24
0.60
1.4
1.2
—
—
—
0
0
8
52
1.54
0.59
2.9
6.7
—
78.71
—
0
14
19
140
1.36
0.58
1.1
1.5
—
—
—
0
0
19
140
1.36
0.58
1.1
1.5
—
—
—
0
0
25
193
1.30
0.57
1.2
1.2
43.94
33.89
u/ml
—
5
17
18
132
1.37
0.57
1.1
1.3
0.69
0.63
nmol/l
0.32
18
123
14
99
1.42
0.54
1.3
1.3
—
—
—
0
0
11
158
0.69
0.53
1.3
1.4
—
—
—
0
0
11
158
0.69
0.53
1.3
1.4
—
—
—
0
0
11
158
0.69
0.53
1.3
1.4
—
—
—
0
0
11
158
0.69
0.53
1.3
1.4
—
—
—
0
0
20
152
1.32
0.52
1.7
1.7
—
—
—
0
0
13
92
1.42
0.50
1.1
1.0
—
—
—
0
0
125
1139
1.11
0.49
2.2
2.3
192.69
128.28
ug/g
0.63
93
892
33
271
1.22
0.49
1.3
1.2
—
—
—
0
0
10
68
1.47
0.47
1.0
1.7
0.88
1.14
promille
—
5
56
7
50
1.40
0.45
1.0
1.0
—
—
—
0
0
53
461
1.16
0.44
1.1
1.0
—
—
—
0
0
31
257
1.21
0.43
1.5
1.5
—
—
—
0
0
161
1498
1.09
0.42
1.5
1.5
—
—
—
0
0
8
57
1.41
0.42
1.3
1.7
—
—
—
0
0
25
305
0.82
0.42
1.6
1.6
—
—
—
0
0
19
149
1.28
0.42
1.2
1.1
—
14.96
—
0
8
10
70
1.43
0.41
1.2
1.6
—
—
—
0
0
11
150
0.73
0.41
1.1
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
16.17
—
0
12
5
34
1.47
0.40
2.2
2.7
—
—
—
0
0
5
34
1.47
0.40
2.2
2.7
—
—
—
0
0
52
456
1.15
0.39
1.3
1.3
—
—
—
0
0
0
19
0.00
0.39
0.0
1.0
—
23.19
—
0
19
44
382
1.16
0.38
1.0
1.1
—
0.90
—
0
5
105
966
1.09
0.37
2.8
3.0
254.53
232.99
ng/l
0.11
96
892
6
46
1.31
0.33
1.7
3.1
—
40751.18
—
0
11
34
294
1.16
0.32
6.1
4.8
1.66
1.62
mg/l
0.09
28
269
53
589
0.90
0.31
1.3
1.3
111.26
247.30
u/ml
1.79
48
535
17
138
1.24
0.30
1.1
1.5
—
—
—
0
0
17
138
1.24
0.30
1.1
1.5
—
—
—
0
0
17
138
1.24
0.30
1.1
1.5
—
—
—
0
0
22
261
0.84
0.30
1.3
1.4
—
—
—
0
0
15
120
1.25
0.30
3.8
3.6
—
—
—
0
0
17
139
1.23
0.29
1.1
1.5
—
—
—
0
0
13
162
0.80
0.28
1.1
1.1
—
—
—
0
0
74
803
0.92
0.28
2.1
2.0
—
—
—
0
0
12
95
1.27
0.26
1.9
2.2
—
—
—
0
0
26
225
1.16
0.26
1.4
1.4
—
—
—
0
0
5
73
0.68
0.26
1.0
1.4
—
335.56
—
0
9
242
2329
1.05
0.26
3.0
3.1
0.80
0.76
ug/l
0.19
168
1598
11
137
0.80
0.24
1.2
1.6
50.33
64.79
%
—
6
92
21
180
1.17
0.24
1.4
1.4
112.13
114.75
u/ml
—
8
32
5
38
1.32
0.23
1.4
1.6
—
—
—
0
0
11
88
1.25
0.22
1.2
1.2
15.45
12.75
u/l
0.27
11
81
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
18
154
1.17
0.21
2.5
1.5
—
—
—
0
0
30
334
0.90
0.20
1.7
1.7
2.39
3.10
mg/l
0.45
23
255
22
193
1.14
0.19
1.9
1.9
191.55
216.83
pmol/l
0.68
22
180
6
52
1.15
0.19
1.8
1.3
251.17
512.00
u/l
—
6
46
29
261
1.11
0.18
2.0
1.7
42.00
40.65
nmol/l
0.07
29
247
7
60
1.17
0.17
1.1
1.2
108.40
164.82
pmol/l
—
7
60
42
453
0.92
0.16
3.3
3.2
37.24
59.93
u/ml
0.41
37
435
107
1117
0.95
0.16
1.7
1.8
1.60
1.50
%
0.47
84
954
117
1132
1.04
0.12
3.9
4.2
4.10
24.47
ug/l
1.97
101
942
16
143
1.12
0.11
1.0
1.2
3.00
5.31
u/ml
—
6
65
17
153
1.11
0.11
1.0
1.1
0.19
2.03
u/ml
—
7
89
14
127
1.10
0.08
1.0
1.1
129.36
116.95
%
0.66
14
116
6
70
0.86
0.07
1.5
1.9
—
—
—
0
0
6
72
0.83
0.07
1.2
1.5
0.89
0.98
g/l
—
6
72
8
76
1.05
0.07
1.0
1.0
251.00
292.60
mg/l
—
8
65
8
76
1.05
0.07
1.1
1.3
—
—
—
0
0
7
80
0.87
0.07
1.0
1.1
—
56.60
—
0
5
8
91
0.88
0.06
1.0
1.5
—
—
—
0
0
70
720
0.97
0.06
2.0
1.9
—
—
—
0
0
10
90
1.11
0.05
1.0
1.4
—
—
—
0
0
31
320
0.97
0.03
2.1
1.7
—
—
—
0
0
26
251
1.04
0.02
1.2
1.2
1.14
2.11
u/ml
—
5
21
13
123
1.06
0.01
1.0
1.0
0.12
1.65
u/ml
—
5
68
14
133
1.05
0.01
1.0
1.1
—
—
—
0
0
41
417
0.98
0.01
2.8
3.4
21.96
3459.75
u/ml
0.81
36
354
10
96
1.04
0.00
1.6
1.2
—
165.00
—
0
18
22
224
0.98
0.00
1.1
1.3
260.89
241.54
miu/ml
—
9
98
14
138
1.01
0.00
1.1
1.1
—
—
—
0
0
40
397
1.01
0.00
2.1
1.8
—
—
—
0
0
26
265
0.98
0.00
1.5
1.6
6171.39
16102.15
e6/l
1.63
18
193
26
255
1.02
0.00
1.2
1.2
4.17
8.97
u/ml
—
7
41
20
195
1.03
0.00
1.3
1.3
—
—
—
0
0
7
71
0.99
0.00
1.1
1.5
—
—
—
0
0
7
71
0.99
0.00
1.1
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
2.40
—
0
5
6
69
0.87
-0.00
2.8
1.5
79.83
83.55
umol/l
—
6
69
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
33.20
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
6.7
—
21.50
—
0
6
9
92
0.98
-0.00
1.6
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
57
0.88
-0.00
1.0
1.4
1.77
1.54
g/l
—
5
57
0
6
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
392.17
—
0
6
10
100
1.00
-0.00
4.8
2.2
—
—
—
0
0
7
76
0.92
-0.00
1.1
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
19.89
—
0
9
0
7
0.00
-0.00
0.0
3.7
—
—
—
0
0
6
60
1.00
-0.00
4.8
1.4
—
—
—
0
0
6
60
1.00
-0.00
4.8
1.4
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_PARASTRA6 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRA6 | 1.239 [1.11, 1.39] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.18 |
During the follow-up period (1.1.1998 — 31.12.2019), 956 out of 3610 females with H7_PARASTRA6 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRA6 | 1.369 [1.21, 1.55] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 985 out of 3415 males with H7_PARASTRA6 died.
Mortality risk
Mortality risk for people of age
years, who have H7_PARASTRA6.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | 0.26% |
| 5 | 0.674% | 1.56% |
| 10 | 1.642% | 4.144% |
| 15 | 3.278% | 7.631% |
| 20 | 5.817% | 12.723% |
Relationships between endpoints
↥Index endpoint: H7_PARASTRA6 – Sixth [abducent] nerve palsy
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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