No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1181 |
4. Check minimum number of eventsNone |
1181 |
5. Include endpointsNone |
1181 |
6. Filter based on genotype QC (FinnGen only) |
1181 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H49
- Name in latin
- Paresis/paralysis nervi abducentis
Similar endpoints
↥List of similar endpoints to
Sixth [abducent] nerve palsy
based on the number of shared cases.
Similar with more cases:
- Paralytic strabismus
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7973 | 4049 | 3894 |
| Only index persons | 7178 | 3707 | 3471 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.11 |
| Only index persons | 0.13 | 0.14 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 63.91 | 64.87 | 62.88 |
| Only index persons | 63.69 | 64.69 | 62.63 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1181 | 574 | 607 |
| Unadjusted period prevalence (%) | 0.23 | 0.20 | 0.27 |
| Median age at first event (years) | 62.57 | 60.31 | 64.72 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1068
- Matched controls
- 10680
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H53.2
ICD-10 Finland
Diplopia
73.2
323.0
460
109
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
323.0
1068
*
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.0
93.1
291
623
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.3
86.0
226
379
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
+∞
69.5
66
*
AA1AD
NOMESCO Finland
CT of head and brain
3.4
65.9
423
1722
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
65.3
62
*
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
+∞
55.7
53
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
11.5
55.2
106
101
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
554.8
54.0
53
*
XCK00
NOMESCO Finland
Perimetry
5.5
51.4
163
336
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.3
45.7
274
1012
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.2
37.0
154
416
CE2W4
NOMESCO Finland
Eye movement mapping
191.4
36.0
37
*
A10AE04
ATC
insulin glargine; parenteral
3.7
35.7
171
522
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
19.1
33.4
51
28
G51.0
ICD-10 Finland
Bell palsy
7.5
32.2
78
111
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.8
30.4
140
411
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.6
29.5
145
449
G35
ICD-10 Finland
Multiple sclerosis
11.5
29.3
55
50
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
8.7
28.9
63
76
TAB00
NOMESCO Finland
Lumbar puncture
5.3
27.9
88
177
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
27.2
26
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.3
27.0
145
479
H50.30
ICD-10 Finland
Intermittent esotropy
277.7
26.8
27
*
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
19.2
25.8
39
21
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.9
25.0
170
658
109
Kela drug reimbursment
Multiple sclerosis
14.5
25.0
42
30
103
Kela drug reimbursment
Diabetes, insulin-treated
2.1
23.8
343
1957
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
17.7
23.2
36
21
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
14.5
22.7
38
27
XCK10
NOMESCO Finland
Photography of fundus of eye
2.7
22.0
160
644
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
21.9
21
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
18.9
21.8
33
18
A10AA02
ATC
NA
4.6
20.8
74
170
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.1
20.8
301
1705
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.4
20.7
107
342
B01AC04
ATC
clopidogrel; oral
2.3
20.5
227
1141
R51.80
ICD-10 Finland
Headache
2.4
18.6
173
792
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.4
18.6
69
166
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
18.4
291
1693
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.5
18.0
54
103
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
3.3
17.9
92
293
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
5.9
17.4
49
87
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.3
17.1
65
160
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
16.7
16
*
H50.51
ICD-10 Finland
Esophoria
172.5
16.5
17
*
H02.2
ICD-10 Finland
Lagophthalmos
23.5
16.5
23
10
T89
ICPC
Diabetes insulin dependent
4.2
16.1
62
155
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
5.5
15.9
47
89
H50.2
ICD-10 Finland
Vertical strabismus
86.4
15.6
17
*
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
19.5
15.6
23
12
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.4
15.6
47
91
A10AE05
ATC
insulin detemir; parenteral
3.2
15.5
84
278
A10AA01
ATC
NA
4.7
15.5
53
118
C10AA05
ATC
atorvastatin; oral
1.7
15.5
435
3038
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
6.8
14.9
37
56
H3601, E113
ICD-10 Finland
NA
7.6
14.8
34
46
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
14.6
14
*
H46
ICD-10 Finland
Optic neuritis
12.8
14.4
25
20
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
7.5
14.3
33
45
A10BA02
ATC
metformin; oral
1.8
14.2
317
2049
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
14.2
486
3563
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
4.4
14.2
51
120
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
14.1
429
3043
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.7
13.9
96
372
PA7BD
NOMESCO Finland
CT angiography of neck and brain
6.1
13.9
37
62
C08CA01
ATC
amlodipine; oral
1.7
13.7
399
2786
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.4
13.7
66
201
H36.01
ICD-10 Finland
Diabetic maculopathy
8.5
13.6
29
35
L03AB07
ATC
interferon beta-1a; parenteral
18.5
13.4
20
11
H52.2
ICD-10 Finland
Astigmatism
26.1
13.4
18
7
CS494
NOMESCO Finland
Other visual field testing
4.9
13.3
43
91
H53.1
ICD-10 Finland
Subjective visual disturbances
2.9
13.2
81
293
T90
ICPC
Diabetes non-insulin dependent
1.8
13.1
263
1638
A10BB01
ATC
glibenclamide; oral
3.2
13.0
68
221
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
13.2
12.9
22
17
R42
ICD-10 Finland
Dizziness and giddiness
1.8
12.6
250
1545
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
12.5
12
*
3785A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Paralytic strabismus
+∞
12.5
12
*
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
10.2
12.5
24
24
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.0
12.5
50
131
SPAT1262
SPAT
Handing over of treatment supplies
1.9
12.3
218
1299
A10BB12
ATC
glimepiride; oral
2.5
12.3
100
427
G70.0
ICD-10 Finland
Myasthenia gravis
38.0
12.2
15
*
C10AA01
ATC
simvastatin; oral
1.6
12.0
482
3635
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
5.1
11.8
36
72
L04AX07
ATC
dimethyl fumarate; oral
30.4
11.7
15
5
A28
ICPC
Limited function/disability NOS
1.9
11.4
177
1003
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
7.7
11.2
25
33
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
11.1
96
423
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.5
11.1
32
60
H3601, E103
ICD-10 Finland
NA
9.3
11.0
22
24
H36.00
ICD-10 Finland
Diabetic background retinopathy
6.7
11.0
27
41
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
43.8
10.9
13
*
H3603, E103
ICD-10 Finland
NA
7.3
10.8
25
35
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
5.9
10.8
29
50
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.3
10.7
39
94
L03AX13
ATC
glatiramer acetate; parenteral
21.7
10.7
15
7
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
13.1
10.7
18
14
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.2
10.6
55
178
H50.52
ICD-10 Finland
Exophoria
60.6
10.6
12
*
H50.9
ICD-10 Finland
Strabismus, unspecified
60.6
10.6
12
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
6.0
10.5
28
48
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
10.4
10
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.9
10.4
41
107
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
12.2
10.4
18
15
E10
ICD-10 Finland
Type 1 diabetes mellitus
5.2
10.4
31
61
H3600, E113
ICD-10 Finland
NA
5.8
10.3
28
49
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.6
10.3
45
128
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.3
10.3
98
454
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.4
10.1
35
81
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
10.0
74
300
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
7.3
10.0
23
32
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.8
10.0
32
68
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
9.9
619
5084
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.1
9.9
120
617
353
Kela drug reimbursment
Cladribine and fingolimod
26.3
9.8
13
5
R53
ICD-10 Finland
Malaise and fatigue
1.7
9.8
206
1288
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
8.5
9.6
20
24
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.4
9.6
33
76
CKC15
NOMESCO Finland
Panretinal photocoagulation
9.2
9.5
19
21
S06.2
ICD-10 Finland
Diffuse brain injury
7.2
9.5
22
31
N07AA02
ATC
pyridostigmine; systemic
15.2
9.5
15
10
A10AE06
ATC
insulin degludec; parenteral
4.0
9.5
37
96
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
6.7
9.5
23
35
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
9.4
173
1036
H50.8
ICD-10 Finland
Other specified strabismus
100.9
9.4
10
*
108
Kela drug reimbursment
Myasthenia gravis
30.3
9.4
12
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
9.4
182
1108
164
Kela drug reimbursment
Fingolimod
21.9
9.4
13
6
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.8
9.3
178
1077
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
4.1
9.3
35
88
H3603, E113
ICD-10 Finland
NA
7.4
9.2
21
29
N03AX12
ATC
gabapentin; oral
1.8
9.2
161
948
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
8.8
287
2019
AAF00
NOMESCO Finland
Ventriculostomy
10.8
8.8
16
15
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
50.4
8.7
10
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
7.0
8.6
20
29
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
16.4
8.6
13
8
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
8.5
77
349
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
7.4
8.5
19
26
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
12.9
8.4
14
11
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
6.3
8.3
21
34
S18
ICPC
Laceration/cut
1.5
8.3
430
3346
H47.1
ICD-10 Finland
Papilloedema, unspecified
10.8
8.3
15
14
N86
ICPC
Multiple sclerosis
9.5
8.3
16
17
F05
ICPC
Visual disturbance other
3.5
8.1
36
105
H52.1
ICD-10 Finland
Myopia
7.3
8.0
18
25
ZXA10
NOMESCO Finland
Bilateral
1.6
7.9
198
1295
H16.0
ICD-10 Finland
Corneal ulcer
2.6
7.8
54
212
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.8
7.8
141
839
H04AA01
ATC
glucagon; nasal, parenteral
3.8
7.8
31
83
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.7
7.7
178
1139
C09AA05
ATC
ramipril; oral
1.5
7.7
266
1885
CBH25
NOMESCO Finland
Tarsorrhaphy
45.3
7.7
9
*
N03AX16
ATC
pregabalin; oral
1.6
7.7
232
1592
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.9
7.7
107
581
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.5
7.6
25
56
L04AA27
ATC
fingolimod; oral
25.2
7.6
10
*
A10BH01
ATC
sitagliptin; oral
1.9
7.6
107
586
H3600, E103
ICD-10 Finland
NA
6.2
7.6
19
31
WX872
NOMESCO Finland
Intensive care
2.4
7.5
59
250
C09AA02
ATC
enalapril; systemic
1.6
7.5
212
1430
WX140
NOMESCO Finland
Parabulbar anesthesy
2.5
7.4
55
226
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.4
261
1861
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.6
7.4
208
1404
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
7.4
159
997
N01
ICPC
Headache
2.0
7.3
87
445
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
6.9
7.3
17
25
AAH50
NOMESCO Finland
Cranial nerve anastomosis
+∞
7.3
7
*
H50.4
ICD-10 Finland
Other and unspecified heterotropia
+∞
7.3
7
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.4
7.3
33
99
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
7.4
7.2
16
22
CKC10
NOMESCO Finland
Local photocoagulation of retina
4.0
7.2
27
69
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
3.2
7.2
35
111
205
Kela drug reimbursment
Chronic hypertension
1.5
7.2
302
2235
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
30.2
7.2
9
*
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.7
7.0
137
831
XCH00
NOMESCO Finland
Eye pressure measurement
2.6
7.0
49
194
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.6
7.0
30
86
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
7.0
7.0
16
23
A10BD03
ATC
metformin and rosiglitazone; systemic
4.5
7.0
23
52
CKC12
NOMESCO Finland
Photocoagulation of retina
2.5
6.9
52
215
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
13.9
6.9
11
8
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
4.4
6.9
23
53
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.8
287
2118
L04AA31
ATC
teriflunomide; oral
40.3
6.8
8
*
N02BE01
ATC
paracetamol; systemic, rectal
1.5
6.7
866
7898
XA800
NOMESCO Finland
Neuropsychological investigation
2.6
6.6
44
171
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
12.3
6.6
11
9
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.2
6.5
61
283
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
3.2
6.5
31
98
L28
ICPC
Limited function/disability (L)
1.6
6.3
160
1047
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.3
313
2385
G91.1
ICD-10 Finland
Obstructive hydrocephalus
8.2
6.3
13
16
H47.2
ICD-10 Finland
Optic atrophy
11.1
6.3
11
10
H49.9
ICD-10 Finland
Paralytic strabismus, unspecified
+∞
6.3
6
*
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
26.8
6.2
8
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.3
6.2
53
235
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
6.2
139
883
ZXA05
NOMESCO Finland
Left side
1.5
6.1
257
1891
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
6.1
203
1423
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
12.6
6.1
10
8
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
69
58
12.57
69.12
1.1
1.1
3.5
4.4
nmol/l
0.14
16
13
98
214
4.90
42.48
1.5
1.5
28.7
47.9
e6/l
0.25
79
165
98
214
4.90
42.48
1.5
1.6
491.0
693.0
e6/l
0.13
81
170
523
3031
2.30
41.70
2.2
2.2
136.0
236.0
u/l
2.96
506
2861
47
53
9.19
38.27
1.1
1.0
1.1
1.1
u/l
0.11
26
28
326
1596
2.44
37.69
1.9
2.2
29.0
29.9
s
1.64
313
1548
46
60
7.94
33.33
1.1
1.0
—
—
—
0
0
60
105
5.97
33.12
1.1
1.1
—
—
—
0
0
54
86
6.53
32.72
1.1
1.0
—
—
—
0
0
46
65
7.32
31.11
1.2
1.1
43.4
40.4
mg/l
0.13
35
55
55
94
6.09
31.09
1.8
1.2
—
—
—
0
0
44
62
7.33
29.82
1.1
1.1
206.8
249.2
mg/l
1.11
36
54
789
5822
2.07
29.61
5.9
5.0
7.3
6.8
mmol/l
7.15
748
5469
18
12
15.22
20.23
1.1
1.0
5.4
6.7
mg/g
0.57
18
12
539
3852
1.73
18.60
4.4
3.9
38.0
50.9
ng/l
0.51
414
2808
47
111
4.37
18.44
1.1
1.1
—
—
—
0
0
19
20
9.64
16.14
1.2
1.4
—
—
—
0
0
597
4525
1.65
15.52
7.3
6.2
1.2
1.2
mmol/l
0.10
539
4098
640
4938
1.65
15.49
8.3
7.0
1.2
1.2
mmol/l
0.01
534
4168
95
395
2.53
14.91
1.9
2.0
35.2
39.9
u/l
1.36
85
351
26
45
5.89
14.50
1.8
1.2
—
—
—
0
0
847
7128
1.67
13.58
4.9
4.1
13.5
13.0
mm/h
0.36
793
6543
202
1177
1.86
13.34
7.1
7.7
1.2
1.2
mmol/l
0.02
152
917
436
3156
1.60
12.98
4.8
4.0
10.5
8.4
mg/mmol
0.42
287
2027
778
6445
1.61
12.94
5.8
4.6
861.5
2710.8
e6/l
0.87
13
104
200
1175
1.85
12.84
7.2
7.7
5.1
5.1
kpa
0.22
183
1121
200
1176
1.84
12.80
7.2
7.6
12.7
12.1
kpa
0.86
183
1123
554
4308
1.54
11.69
5.0
4.9
35.0
35.2
g/l
0.29
510
3997
424
3128
1.55
11.25
3.9
3.2
7.2
7.6
mmol/l
0.96
344
2598
12
11
11.01
11.07
1.1
1.4
—
—
—
0
0
20
35
5.80
11.03
1.1
1.1
772.6
115.5
ng/l
—
5
6
16
23
7.04
10.59
1.1
1.2
—
—
—
0
0
36
106
3.47
10.48
1.4
1.7
—
—
—
0
0
12
12
10.09
10.45
1.2
1.3
—
—
—
0
0
63
260
2.50
10.08
2.7
2.5
80.6
128.9
ug/min
0.53
38
155
1041
9488
1.82
10.06
20.4
15.4
22.5
25.3
mg/l
2.09
869
7578
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
24
57
4.28
9.40
1.1
1.1
—
—
—
0
0
16
27
5.99
9.13
1.0
1.1
—
—
—
0
0
25
63
4.03
9.08
2.1
2.2
—
—
—
0
0
145
857
1.79
9.00
3.1
3.0
66.3
66.3
g/l
0.00
129
780
666
5557
1.46
8.96
11.2
8.9
4.6
4.2
e9/l
1.85
584
4845
32
97
3.36
8.94
1.3
1.7
—
—
—
0
0
854
7495
1.50
8.75
8.8
7.6
82.8
79.0
u/l
0.74
802
7021
579
4730
1.44
8.58
4.5
3.8
0.0
0.0
estimate
0.42
100
877
16
29
5.58
8.51
1.1
1.2
—
—
—
0
0
16
29
5.58
8.51
1.1
1.1
—
—
—
0
0
22
53
4.21
8.48
1.1
1.1
—
—
—
0
0
959
8650
1.58
8.46
5.5
4.7
1.9
2.1
mu/l
0.51
873
7833
206
1362
1.62
8.43
6.1
6.0
1.1
1.0
mmol/l
0.37
189
1255
1064
9857
1.80
8.42
24.3
18.0
139.5
139.6
mmol/l
0.36
1040
9580
156
963
1.71
8.31
8.1
8.5
119.2
121.0
g/l
0.52
150
929
1065
9884
1.79
8.17
24.2
18.2
4.0
4.0
mmol/l
0.23
1036
9595
19
42
4.58
8.14
1.1
1.2
—
—
—
0
0
570
4676
1.42
8.07
6.0
5.1
0.0
0.0
estimate
0.50
107
908
12
17
7.12
8.00
1.1
1.2
—
—
—
0
0
570
4682
1.42
7.98
4.5
3.7
0.0
0.0
estimate
0.00
104
904
15
28
5.41
7.74
1.0
1.1
—
—
—
0
0
296
2161
1.49
7.72
2.9
2.6
3.6
5.4
e6/l
3.07
262
1898
144
887
1.71
7.72
3.0
2.2
358.0
378.7
nmol/l
0.63
134
807
111
651
1.78
7.07
9.8
6.7
25.0
24.4
mmol/l
1.08
102
607
23
67
3.48
6.86
4.6
2.0
18.0
21.1
nmol/l
0.51
23
60
482
3919
1.39
6.82
2.3
2.2
77.4
77.1
nmol/l
0.08
431
3462
807
7145
1.41
6.78
4.6
3.9
15.1
14.9
pmol/l
1.11
727
6455
148
951
1.64
6.75
6.6
7.7
9.8
10.3
mmol/l
0.42
137
905
448
3612
1.39
6.61
4.8
4.0
—
—
—
0
0
13
25
5.25
6.50
4.9
2.1
—
—
—
0
0
102
602
1.76
6.37
1.7
1.5
—
—
—
0
0
606
5156
1.36
6.28
6.7
6.3
10.6
11.6
umol/l
2.15
582
4891
46
207
2.27
6.17
2.6
1.6
0.7
0.9
nmol/l
1.45
36
171
23
73
3.19
6.04
3.6
2.2
874.5
769.9
e6/l
0.27
13
25
9
6
15.10
5.91
1.0
1.0
—
—
—
0
0
9
6
15.10
5.91
2.2
1.2
—
—
—
0
0
204
1453
1.49
5.88
2.8
2.5
2.2
2.3
g/l
2.98
188
1351
25
85
2.98
5.86
2.4
2.3
622.8
657.1
ml
0.21
17
52
15
36
4.21
5.83
1.0
1.1
—
—
—
0
0
498
4149
1.35
5.75
2.1
2.1
95.4
94.0
pmol/l
0.25
235
2175
224
1632
1.46
5.75
3.6
3.5
0.8
0.8
mmol/l
0.15
206
1524
91
536
1.76
5.74
7.5
10.5
24.3
24.4
mmol/l
0.16
81
501
355
2812
1.38
5.66
4.0
3.2
0.2
0.5
e6/l
4.25
288
2151
956
8825
1.44
5.57
8.5
6.0
44.4
40.2
mmol/mol
16.84
870
8129
13
29
4.52
5.52
1.2
1.1
—
—
—
0
0
46
218
2.16
5.48
1.7
1.7
3.3
4.4
iu/l
0.44
20
65
18
53
3.43
5.32
1.0
1.2
—
—
—
0
0
191
1369
1.47
5.31
2.8
2.6
22.5
23.1
%
0.21
160
1175
272
2085
1.40
5.23
5.1
4.1
1.0
1.0
kg/l
0.12
45
299
325
2566
1.37
5.22
5.0
4.1
0.0
0.0
estimate
0.88
107
871
230
1713
1.43
5.22
1.9
1.9
—
—
—
0
0
214
1573
1.44
5.21
2.8
2.5
12.1
12.9
umol/l
0.96
194
1451
20
65
3.11
5.08
2.8
2.4
11.6
12.9
%
—
5
36
258
1978
1.39
4.93
1.8
1.8
1110.6
1184.3
nmol/l
0.71
203
1490
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
64
356
1.84
4.90
2.5
3.0
0.4
0.4
u/ml
0.24
27
203
268
2071
1.38
4.88
1.7
1.8
1.5
1.3
mg/l
0.35
212
1596
537
4597
1.31
4.88
4.6
4.1
—
—
—
0
0
8
7
11.50
4.79
1.0
1.3
—
—
—
0
0
303
2410
1.35
4.56
2.7
2.4
—
—
—
0
0
9
11
8.23
4.56
1.1
1.3
—
—
—
0
0
38
181
2.14
4.52
1.5
1.7
—
—
—
0
0
140
978
1.49
4.42
4.3
3.9
2.1
2.0
mmol/l
0.13
102
781
54
299
1.84
4.23
1.8
1.6
—
—
—
0
0
1058
10067
1.49
4.23
13.6
10.7
26.3
26.0
u/l
0.24
1012
9688
74
451
1.68
4.19
1.7
1.8
3.3
2.1
ug/l
0.26
61
404
10
23
4.38
4.09
2.7
1.6
—
—
—
0
0
164
1200
1.43
4.08
10.1
7.7
—
—
—
0
0
18
63
2.89
4.07
4.4
2.7
0.3
0.2
e9/l
0.67
18
55
401
3365
1.29
4.04
2.9
3.4
2.3
2.3
mmol/l
0.15
338
2912
371
3090
1.29
3.94
3.3
3.2
1639.6
1561.6
ng/l
0.11
318
2662
26
112
2.35
3.94
4.5
2.7
—
—
—
0
0
138
986
1.45
3.90
4.1
3.9
5.8
5.8
kpa
0.30
129
956
50
280
1.82
3.81
1.7
1.6
0.1
24.6
iu/ml
0.49
14
49
35
656
0.52
3.69
1.5
1.7
—
—
—
0
0
315
2592
1.29
3.63
2.5
2.2
3.1
3.1
mg/l
0.03
272
2187
63
385
1.67
3.57
2.5
2.6
4.9
3.8
g/l
0.99
37
274
99
675
1.51
3.54
3.4
4.0
1.9
1.7
mmol/l
0.23
74
514
63
386
1.67
3.53
2.5
2.6
7.6
7.4
g/l
0.38
39
285
63
386
1.67
3.53
2.5
2.6
—
—
—
0
0
54
320
1.72
3.43
1.2
1.2
0.4
1.3
u/ml
—
8
24
56
337
1.69
3.37
3.8
3.9
48.7
74.3
mg/l
0.68
45
268
219
1732
1.32
3.36
3.6
2.8
1.3
1.1
e6/l
0.48
129
1008
56
339
1.68
3.30
3.8
3.9
43.4
74.5
mg/l
0.39
46
271
126
915
1.42
3.28
6.7
7.5
1.3
1.4
mmol/l
1.20
120
873
159
1202
1.37
3.28
1.7
1.8
—
—
—
0
0
13
43
3.05
3.25
1.5
2.0
86.7
99.5
umol/l
—
6
28
102
713
1.47
3.25
3.4
4.0
5.2
5.2
kpa
0.45
95
666
110
781
1.45
3.24
3.0
2.8
60.9
63.6
ml/min/173m2
0.30
48
315
116
832
1.44
3.24
3.9
3.2
4.5
4.6
kpa
0.20
105
803
90
614
1.50
3.23
5.5
8.4
24.9
24.8
mmol/l
0.05
90
609
7
11
6.39
3.18
1.3
1.4
—
—
—
0
0
26
124
2.12
3.15
12.6
6.4
8.7
6.8
mmol/l
1.33
21
101
158
1201
1.36
3.15
1.8
1.8
—
—
—
0
0
127
931
1.41
3.14
2.6
2.5
7.1
7.3
ug/l
0.03
110
820
40
223
1.82
3.14
1.9
2.4
130.4
129.1
g/l
0.11
33
164
54
329
1.67
3.12
3.9
3.9
1.7
1.8
ratio
—
5
26
21
92
2.31
3.11
1.4
1.5
—
—
—
0
0
21
92
2.31
3.11
1.4
1.5
—
—
—
0
0
21
92
2.31
3.11
1.4
1.5
—
—
—
0
0
12
39
3.10
3.09
1.0
1.0
1202.7
1588.8
miu/ml
0.61
12
39
240
1946
1.29
3.06
1.4
1.2
1.6
1.5
u/ml
0.05
64
512
8
16
5.03
3.05
1.1
1.1
—
—
—
0
0
42
240
1.78
3.05
1.5
1.7
—
—
—
0
0
361
3079
1.25
3.02
3.3
2.5
61.1
57.0
u/l
0.26
329
2843
147
1116
1.36
2.96
3.3
2.9
6.5
8.4
umol/l
0.91
134
990
303
2539
1.26
2.95
1.9
1.6
1.3
1.4
mmol/l
0.18
250
2117
57
361
1.61
2.86
2.5
2.6
10.1
10.7
g/l
0.59
46
302
12
41
2.95
2.86
1.2
1.0
—
—
—
0
0
8
18
4.47
2.79
1.0
1.4
—
—
—
0
0
236
1931
1.28
2.79
4.1
4.0
688.5
436.3
ng/l
0.25
197
1560
160
1243
1.33
2.78
4.6
4.6
33.7
32.2
%
0.90
118
833
458
4040
1.22
2.74
3.1
2.8
176.7
141.1
ug/l
0.85
416
3701
150
1158
1.34
2.72
5.5
4.1
236.1
249.9
u/l
0.55
142
1094
663
6067
1.21
2.71
3.6
3.2
61.6
50.8
u/l
1.05
616
5638
35
199
1.78
2.62
1.8
2.1
6338.6
3477.5
u/l
—
10
78
37
215
1.74
2.58
2.4
1.4
12.0
9.8
u/l
0.35
31
166
27
144
1.90
2.47
1.4
1.6
—
—
—
0
0
64
432
1.51
2.47
5.9
4.8
1.8
1.6
%
0.53
59
407
15
63
2.40
2.47
3.0
2.5
—
—
—
0
0
55
360
1.55
2.44
2.6
2.7
3.2
3.2
g/l
0.13
37
278
31
174
1.80
2.44
1.2
1.6
—
—
—
0
0
1083
10499
1.38
2.43
30.6
22.5
249.8
245.7
e9/l
1.18
1060
10194
51
329
1.57
2.41
1.5
1.5
—
145.0
—
0
12
6
12
5.02
2.40
3.2
1.3
—
—
—
0
0
1083
10503
1.38
2.39
30.5
22.4
4.5
4.5
e12/l
0.26
1055
10163
1083
10504
1.37
2.38
30.6
22.5
7.2
6.8
e9/l
3.33
1055
10162
936
8913
1.24
2.37
18.4
14.3
78.0
78.4
ml/min/173m2
0.19
792
7370
21
104
2.04
2.37
1.2
1.5
—
—
—
0
0
258
2173
1.24
2.37
1.7
1.7
441.2
8268588.9
pmol/l
0.77
202
1790
1083
10505
1.37
2.37
30.7
22.6
133.6
134.8
g/l
1.73
1069
10317
71
496
1.46
2.33
4.5
4.3
24.1
24.2
mmol/l
0.10
60
450
49
316
1.57
2.33
1.4
1.3
—
—
—
0
0
152
1203
1.30
2.33
3.6
2.6
1.8
1.8
%
0.09
131
1064
10
35
2.87
2.30
1.2
1.2
—
—
—
0
0
37
224
1.67
2.26
1.1
1.1
—
—
—
0
0
40
249
1.63
2.21
1.5
1.7
—
—
—
0
0
37
228
1.64
2.13
2.7
2.7
17.0
15.9
%
0.81
24
117
18
88
2.06
2.12
1.1
1.3
—
—
—
0
0
5
10
5.02
2.07
1.2
1.1
—
—
—
0
0
6
15
4.02
2.04
1.8
2.0
—
—
—
0
0
101
771
1.34
2.02
4.0
3.8
101.5
89.7
ng/l
0.42
89
664
38
242
1.59
1.94
1.5
3.1
27.2
35.0
umol/l
1.13
33
198
62
440
1.43
1.92
3.4
4.5
25.3
24.8
mmol/l
0.77
56
412
56
391
1.45
1.89
1.8
1.7
—
—
—
0
0
26
152
1.73
1.84
1.2
1.5
—
—
—
0
0
41
270
1.54
1.83
2.0
1.5
—
—
—
0
0
196
1648
1.23
1.83
4.0
3.0
2.7
1.9
e6/l
0.57
104
929
12
53
2.28
1.81
2.8
2.5
—
—
—
0
0
23
132
1.76
1.74
1.1
1.6
—
—
—
0
0
181
1519
1.23
1.72
1.2
1.3
38.1
38.0
iu/ml
0.00
40
471
224
1921
1.20
1.72
2.8
3.1
2.5
2.5
mmol/l
0.06
188
1678
5
13
3.86
1.71
1.0
1.1
—
—
—
0
0
103
810
1.30
1.70
4.8
4.3
1.2
1.2
mmol/l
0.04
87
705
33
212
1.57
1.66
1.3
1.6
—
—
—
0
0
48
335
1.45
1.65
2.8
3.0
1.8
1.4
g/l
0.21
39
288
17
90
1.90
1.65
1.1
1.2
—
—
—
0
0
119
959
1.27
1.63
2.3
2.3
0.2
0.2
g/l
0.35
104
894
291
2566
1.18
1.63
3.5
2.8
2687.9
7691.4
umol/l
1.26
249
2207
113
905
1.27
1.63
2.6
2.4
48.6
39.3
u/l
0.21
86
764
343
3069
1.17
1.60
3.3
3.3
38.6
33.8
u/l
0.52
325
2910
8
32
2.51
1.60
1.9
1.3
—
—
—
0
0
67
502
1.35
1.56
3.7
3.2
4.5
4.5
pmol/l
0.16
61
435
5
15
3.34
1.52
2.0
2.6
—
—
—
0
0
7
27
2.60
1.51
1.0
1.3
—
—
—
0
0
33
218
1.53
1.50
1.3
1.3
—
—
—
0
0
23
139
1.67
1.49
1.3
1.6
—
—
—
0
0
276
2444
1.17
1.47
1.6
1.6
20.6
20.4
nmol/l
0.04
236
2051
30
195
1.55
1.46
3.1
3.5
61.4
58.1
%
0.77
30
195
5
16
3.13
1.44
2.0
2.6
—
—
—
0
0
39
270
1.46
1.43
2.0
1.7
—
—
—
0
0
96
768
1.27
1.42
2.0
1.7
—
—
—
0
0
40
279
1.45
1.42
2.4
1.7
—
—
—
0
0
814
7782
1.15
1.41
24.7
18.7
13.9
13.8
%
1.17
799
7600
29
189
1.55
1.41
3.2
3.2
4.2
4.4
e9/l
0.19
29
189
955
9243
1.17
1.38
5.4
4.7
6.5
6.0
mmol/l
8.93
865
8356
64
487
1.33
1.37
1.8
1.9
1.6
1.5
g/l
0.33
56
434
130
1082
1.23
1.37
3.6
3.5
—
—
—
0
0
50
366
1.38
1.37
1.9
2.9
—
—
—
0
0
5
17
2.95
1.36
1.2
2.8
—
—
—
0
0
13
68
1.92
1.33
1.6
1.3
—
—
—
0
0
13
68
1.92
1.33
1.6
1.3
—
—
—
0
0
64
490
1.32
1.33
3.8
2.7
0.7
0.7
%
0.24
59
476
43
309
1.41
1.31
2.9
2.7
36.4
37.3
g/l
0.41
35
262
9
43
2.10
1.30
1.6
1.7
—
—
—
0
0
9
43
2.10
1.30
1.6
1.7
—
—
—
0
0
9
44
2.05
1.27
1.6
1.7
—
—
—
0
0
10
49
2.05
1.22
1.4
2.5
526.7
1582.8
u/ml
—
10
49
39
280
1.41
1.21
1.3
1.4
270.1
267.6
ug/g
0.03
27
165
18
109
1.66
1.19
1.5
1.8
—
1872.0
—
0
5
6
26
2.31
1.19
1.3
1.3
—
—
—
0
0
25
167
1.51
1.13
5.2
4.1
1.2
1.3
%
0.13
20
140
7
30
2.34
1.12
2.0
1.3
—
—
—
0
0
958
9317
1.15
1.10
5.4
4.5
4.4
4.6
mmol/l
5.51
885
8570
977
9517
1.15
1.09
5.9
5.0
2.5
2.7
mmol/l
6.92
899
8689
98
1172
0.82
1.09
1.4
1.4
—
—
—
0
0
406
3764
1.12
1.07
5.3
5.2
3.1
3.1
ug/l
0.01
356
3344
55
427
1.30
1.07
2.1
1.9
—
—
—
0
0
572
5406
1.11
1.07
2.7
2.8
—
—
—
0
0
71
571
1.26
1.06
1.3
1.2
163.6
155.0
iu/ml
0.07
30
217
81
662
1.24
1.05
1.7
1.7
—
—
—
0
0
32
229
1.41
1.04
6.9
3.9
21.1
28.9
mg/l
1.09
21
142
167
1464
1.16
1.03
1.2
1.3
18.5
12.0
u/ml
0.36
60
552
7
34
2.06
1.03
1.3
1.2
109.1
110.8
%
—
7
28
30
213
1.42
1.02
1.3
1.3
—
—
—
0
0
30
213
1.42
1.02
1.3
1.3
—
—
—
0
0
18
115
1.57
1.00
1.2
1.0
—
—
—
0
0
9
49
1.84
0.98
1.4
1.4
—
—
—
0
0
949
9244
1.14
0.98
5.2
4.5
1.4
1.4
mmol/l
1.45
874
8436
14
84
1.67
0.98
1.4
1.3
—
—
—
0
0
919
8936
1.13
0.97
4.7
4.0
1.4
1.3
mmol/l
1.33
834
8098
9
50
1.81
0.96
1.1
1.2
—
—
—
0
0
329
3033
1.12
0.95
4.4
4.4
22.7
21.1
%
0.88
158
1518
25
174
1.45
0.95
1.2
1.2
43.9
27.9
u/ml
—
5
14
88
735
1.21
0.95
2.5
2.2
12.6
12.6
nmol/l
0.02
78
643
18
269
0.66
0.94
1.3
1.6
—
—
—
0
0
9
52
1.74
0.92
1.2
1.8
—
—
—
0
0
25
177
1.42
0.89
2.4
1.9
1.8
1.7
mmol/l
0.23
25
172
19
128
1.49
0.86
2.2
2.4
25.0
22.8
mg/l
—
6
33
8
45
1.78
0.84
3.3
4.0
—
—
—
0
0
18
121
1.50
0.83
1.1
1.3
0.7
0.6
nmol/l
0.29
18
113
8
48
1.67
0.79
2.9
7.1
—
78.7
—
0
14
7
124
0.56
0.78
1.1
1.6
—
—
—
0
0
31
235
1.33
0.76
1.5
1.3
—
—
—
0
0
20
278
0.71
0.75
1.4
1.4
—
—
—
0
0
17
116
1.47
0.74
1.1
1.2
1.6
2.3
u/ml
—
8
38
9
55
1.64
0.73
1.8
1.6
—
—
—
0
0
9
55
1.64
0.73
1.8
1.6
—
—
—
0
0
9
55
1.64
0.73
1.8
1.6
—
—
—
0
0
9
55
1.64
0.73
1.8
1.6
—
—
—
0
0
5
25
2.00
0.72
1.0
1.8
—
—
—
0
0
10
159
0.63
0.72
1.4
1.5
—
—
—
0
0
17
117
1.46
0.72
1.5
1.8
—
—
—
0
0
13
85
1.54
0.69
1.4
1.7
—
—
—
0
0
12
180
0.66
0.68
1.6
1.5
—
—
—
0
0
7
43
1.63
0.67
1.0
1.0
—
—
—
0
0
12
79
1.52
0.62
1.6
1.6
2.8
3.8
mg/l
1.31
12
74
28
217
1.30
0.62
1.2
1.4
—
—
—
0
0
8
49
1.64
0.62
1.0
1.0
—
—
—
0
0
10
64
1.57
0.58
1.2
1.6
—
—
—
0
0
8
53
1.51
0.58
1.3
1.7
—
—
—
0
0
36
292
1.24
0.57
2.4
1.4
25.3
27.3
iu/l
0.16
31
249
8
55
1.46
0.56
7.6
3.7
—
—
—
0
0
35
284
1.24
0.56
1.5
1.2
—
—
—
0
0
35
286
1.23
0.53
1.5
1.2
—
—
—
0
0
19
143
1.33
0.52
1.7
1.7
—
—
—
0
0
49
419
1.18
0.48
1.1
1.0
—
—
—
0
0
12
85
1.42
0.47
1.1
1.0
—
—
—
0
0
94
1041
0.89
0.46
1.6
1.8
1.6
1.5
%
0.30
71
888
18
138
1.31
0.45
1.2
1.1
—
15.0
—
0
8
11
151
0.73
0.43
1.3
1.4
—
—
—
0
0
11
151
0.73
0.43
1.3
1.4
—
—
—
0
0
11
151
0.73
0.43
1.3
1.4
—
—
—
0
0
11
151
0.73
0.43
1.3
1.4
—
—
—
0
0
67
753
0.88
0.42
2.1
2.0
—
—
—
0
0
5
34
1.47
0.40
2.2
2.7
—
—
—
0
0
5
34
1.47
0.40
2.2
2.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
1.2
—
0
11
0
19
0.00
0.39
0.0
1.0
—
23.2
—
0
19
19
152
1.25
0.37
1.6
1.3
—
—
—
0
0
149
1393
1.08
0.36
24.0
27.2
1.2
1.3
inr
0.84
16
182
6
42
1.43
0.35
1.7
3.1
—
44766.5
—
0
10
14
108
1.30
0.35
3.9
3.6
—
—
—
0
0
11
144
0.76
0.33
1.1
1.1
—
—
—
0
0
29
247
1.18
0.33
1.4
1.2
—
—
—
0
0
48
426
1.13
0.33
1.4
1.3
—
—
—
0
0
6
47
1.28
0.32
1.8
1.3
251.2
543.5
u/l
—
6
42
16
128
1.25
0.32
1.0
1.1
0.2
1.6
u/ml
—
6
55
28
239
1.18
0.31
1.4
1.5
—
—
—
0
0
40
354
1.13
0.29
1.0
1.1
—
0.9
—
0
5
20
167
1.20
0.28
1.4
1.4
112.1
114.4
u/ml
—
8
30
32
280
1.15
0.27
6.3
4.5
1.7
1.6
mg/l
0.24
26
255
113
1062
1.07
0.26
3.8
4.2
4.1
25.4
ug/l
1.94
97
892
12
95
1.27
0.26
1.3
1.3
—
—
—
0
0
21
245
0.85
0.25
1.3
1.4
—
—
—
0
0
859
8491
1.04
0.25
20.9
16.5
38.2
39.5
%
2.26
545
5814
27
307
0.88
0.24
1.7
1.7
2.5
3.0
mg/l
0.25
21
233
95
893
1.07
0.23
2.9
3.0
268.1
228.4
ng/l
0.19
86
825
7
92
0.76
0.22
3.4
2.4
—
—
—
0
0
25
284
0.88
0.22
1.6
1.6
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
49
532
0.92
0.20
1.3
1.3
119.1
243.2
u/ml
1.36
44
484
63
676
0.93
0.20
2.0
1.9
—
—
—
0
0
10
80
1.25
0.20
1.1
1.2
16.4
13.0
u/l
—
10
75
26
232
1.12
0.18
1.2
1.2
1.1
2.1
u/ml
—
5
21
5
67
0.75
0.17
1.4
1.9
—
—
—
0
0
5
69
0.72
0.17
1.0
1.3
—
418.6
—
0
7
8
69
1.16
0.16
1.1
1.2
—
—
—
0
0
13
151
0.86
0.15
1.1
1.1
—
—
—
0
0
20
178
1.13
0.15
1.6
1.8
189.9
215.9
pmol/l
0.68
20
165
226
2203
1.03
0.15
3.0
3.1
0.8
0.8
ug/l
0.23
158
1513
26
236
1.10
0.15
1.2
1.2
4.2
9.1
u/ml
—
7
40
9
83
1.08
0.14
1.7
1.8
—
—
—
0
0
7
89
0.79
0.14
1.0
1.6
—
—
—
0
0
39
415
0.94
0.11
3.3
3.1
39.5
63.5
u/ml
0.40
34
397
16
143
1.12
0.11
4.4
2.4
15773.7
34.3
u/ml
0.48
16
136
22
201
1.10
0.11
1.4
1.4
—
—
—
0
0
26
240
1.09
0.11
1.8
1.7
43.0
40.9
nmol/l
0.10
26
227
15
134
1.12
0.11
1.1
1.5
—
—
—
0
0
15
134
1.12
0.11
1.1
1.5
—
—
—
0
0
16
144
1.11
0.10
2.7
1.6
—
—
—
0
0
143
1394
1.03
0.10
1.5
1.5
—
—
—
0
0
7
68
1.03
0.08
1.1
1.5
—
—
—
0
0
7
68
1.03
0.08
1.1
1.5
—
—
—
0
0
6
71
0.84
0.07
1.2
1.2
—
—
—
0
0
26
245
1.06
0.07
1.5
1.6
6171.4
16513.3
e6/l
1.66
18
179
28
295
0.95
0.06
2.1
1.8
—
—
—
0
0
14
132
1.06
0.02
1.1
1.5
—
—
—
0
0
14
132
1.06
0.02
1.1
1.5
—
—
—
0
0
14
132
1.06
0.02
1.1
1.5
—
—
—
0
0
13
123
1.06
0.01
1.1
1.1
—
—
—
0
0
14
133
1.05
0.01
1.1
1.5
—
—
—
0
0
12
114
1.05
0.00
1.0
1.1
132.1
115.3
%
0.81
12
103
12
118
1.02
0.00
1.0
1.1
—
—
—
0
0
20
202
0.99
0.00
1.1
1.3
227.4
246.7
miu/ml
—
7
91
18
183
0.98
0.00
1.3
1.3
—
—
—
0
0
37
367
1.01
0.00
2.1
1.8
—
—
—
0
0
0
6
0.00
0.00
0.0
5.0
—
392.2
—
0
6
0
5
0.00
0.00
0.0
1.6
—
2.4
—
0
5
0
6
0.00
0.00
0.0
6.7
—
21.5
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
2.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
8
87
0.92
0.00
1.8
1.2
—
162.9
—
0
17
9
89
1.01
0.00
1.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
3.7
—
—
—
0
0
6
59
1.02
0.00
4.8
1.4
—
—
—
0
0
6
59
1.02
0.00
4.8
1.4
—
—
—
0
0
7
74
0.95
0.00
1.0
1.0
254.0
292.6
mg/l
—
7
65
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
7
77
0.91
0.00
1.0
1.1
—
56.6
—
0
5
0
9
0.00
0.00
0.0
1.6
—
19.9
—
0
9
Mortality – FinRegistry
↥Association
Association between endpoint H7_PARASTRA6 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRA6 | 1.239 [1.11, 1.39] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.18 |
During the follow-up period (1.1.1998 — 31.12.2019), 956 out of 3610 females with H7_PARASTRA6 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRA6 | 1.369 [1.21, 1.55] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 985 out of 3415 males with H7_PARASTRA6 died.
Mortality risk
Mortality risk for people of age
years, who have H7_PARASTRA6.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.088% | 0.26% |
| 5 | 0.674% | 1.56% |
| 10 | 1.642% | 4.144% |
| 15 | 3.278% | 7.631% |
| 20 | 5.817% | 12.723% |
Relationships between endpoints
↥Index endpoint: H7_PARASTRA6 – Sixth [abducent] nerve palsy
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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