paralytic strabismus: An ocular deviation caused by a palsy to one or more of the extraocular muscles or nerves supplying them. [database_cross_reference: ORCID:0000-0003-0986-4123][database_cross_reference: ORCID:0000-0003-0986-4123]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2526 |
4. Check minimum number of eventsNone |
2526 |
5. Include endpoints |
2677 |
6. Filter based on genotype QC (FinnGen only) |
2677 |
Control definitions (FinnGen only)
- Control exclude
- H7_OCUMUSCLE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- H49-H52
- Name in latin
- Strabismus paralyticus
Similar endpoints
↥List of similar endpoints to
Paralytic strabismus
based on the number of shared cases.
Similar with more cases:
- Strabismus
- Disorders of ocular muscles, binocular movement, accommodation and refraction
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 18942 | 9349 | 9495 |
| Only index persons | 16522 | 8232 | 8290 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.27 | 0.27 | 0.27 |
| Only index persons | 0.31 | 0.30 | 0.32 |
| Median age at first event (years) | |||
| Whole population | 61.07 | 61.75 | 60.34 |
| Only index persons | 60.55 | 61.10 | 60.01 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2677 | 1333 | 1344 |
| Unadjusted period prevalence (%) | 0.52 | 0.45 | 0.59 |
| Median age at first event (years) | 60.35 | 57.13 | 63.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2427
- Matched controls
- 24271
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
7254.0
323.0
572
*
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
+∞
323.0
1069
*
H53.2
ICD-10 Finland
Diplopia
66.6
323.0
898
212
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
3153.3
323.0
722
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
7.6
190.6
490
785
XCW99
NOMESCO Finland
Other investigative procedure of eye
5.6
190.1
636
1445
H50.2
ICD-10 Finland
Vertical strabismus
530.1
152.4
150
*
AA1AD
NOMESCO Finland
CT of head and brain
3.4
148.6
947
3813
CEC00
NOMESCO Finland
Recession of extraocular muscle
+∞
110.2
105
*
XCK00
NOMESCO Finland
Perimetry
5.1
106.0
366
815
Z01.0
ICD-10 Finland
Examination of eyes and vision
3.2
98.2
614
2305
CEC10
NOMESCO Finland
Recession and resection of extraocular muscle
965.1
95.6
93
*
3785A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Paralytic strabismus
+∞
91.2
87
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
4.4
90.2
360
923
H50.0
ICD-10 Finland
Convergent concomitant strabismus
+∞
82.8
79
*
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
7.7
80.9
196
272
37304
ICD-8 Finland
Strabismus, paralyticus. Paresis nervorum III, IV, VI
+∞
76.4
73
*
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
19.5
67.1
103
55
CE2W4
NOMESCO Finland
Eye movement mapping
141.9
65.2
69
5
TAB00
NOMESCO Finland
Lumbar puncture
5.2
62.8
206
424
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
3.1
51.0
309
1090
R51.80
ICD-10 Finland
Headache
2.5
47.7
414
1819
H49.9
ICD-10 Finland
Paralytic strabismus, unspecified
+∞
46.0
44
*
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
7.2
45.9
115
167
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.7
45.5
355
1463
G51.0
ICD-10 Finland
Bell palsy
5.9
44.9
131
234
CEW99
NOMESCO Finland
Other operation on extraocular muscle
+∞
43.9
42
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
435.1
43.3
43
*
CEC60
NOMESCO Finland
Transposition of extraocular muscle with adjustable suture
+∞
41.8
40
*
G35
ICD-10 Finland
Multiple sclerosis
8.8
40.6
89
105
H50.52
ICD-10 Finland
Exophoria
89.6
39.9
44
5
AAB10
NOMESCO Finland
Partial excision of intracranial lesion
11.5
39.7
75
67
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.9
38.0
250
924
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
8.4
37.5
84
103
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
6.2
37.4
103
171
H50.30
ICD-10 Finland
Intermittent esotropy
192.9
36.9
38
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
3.2
36.8
208
693
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.8
36.6
161
440
A10AE04
ATC
insulin glargine; parenteral
2.6
35.7
294
1239
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
35.2
984
6811
H02.4
ICD-10 Finland
Ptosis of eyelid
4.7
34.8
122
269
CEC30
NOMESCO Finland
Resection of extraocular muscle
+∞
34.4
33
*
H49.8
ICD-10 Finland
Other paralytic strabismus
+∞
34.4
33
*
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
14.0
34.4
59
43
B01AC04
ATC
clopidogrel; oral
2.1
34.3
465
2490
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
8.6
34.0
75
90
109
Kela drug reimbursment
Multiple sclerosis
10.9
33.7
65
61
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
33.5
1081
7779
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.6
33.4
257
1042
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
11.6
32.6
61
54
XCK10
NOMESCO Finland
Photography of fundus of eye
2.4
31.6
306
1401
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
11.9
30.4
56
48
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
28.3
422
2329
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
2.7
27.6
205
811
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
27.1
180
667
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
5.7
27.1
79
142
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.5
26.8
229
982
H50.9
ICD-10 Finland
Strabismus, unspecified
273.9
26.8
27
*
H50.51
ICD-10 Finland
Esophoria
97.8
26.7
29
*
G70.0
ICD-10 Finland
Myasthenia gravis
14.9
26.5
44
30
A10AA02
ATC
NA
3.6
26.2
124
361
H50.31
ICD-10 Finland
Intermittent exotropia
+∞
26.1
25
*
R42
ICD-10 Finland
Dizziness and giddiness
1.8
25.4
535
3321
N07AA02
ATC
pyridostigmine; systemic
12.7
25.3
45
36
CS494
NOMESCO Finland
Other visual field testing
4.6
24.9
89
201
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
3.5
24.3
118
351
D32.06
ICD-10 Finland
Benign tumor of the meninges os petrosum or clivus area
48.9
24.3
29
6
9530/0-C70.0
ICD-O-3
Meningioma, NOS, of cerebral meninges
10.9
24.1
46
43
H49.4
ICD-10 Finland
Progressive external ophthalmoplegia
242.2
23.7
24
*
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
8.9
23.0
49
56
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
3.5
23.0
111
329
CEC90
NOMESCO Finland
Total transposition of extraocular muscle or muscles
+∞
22.9
22
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
22.8
170
676
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
9.5
22.5
46
49
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
3.2
22.4
124
407
H50.8
ICD-10 Finland
Other specified strabismus
+∞
21.9
21
*
108
Kela drug reimbursment
Myasthenia gravis
16.1
21.9
35
22
H02.2
ICD-10 Finland
Lagophthalmos
17.2
21.8
34
20
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
21.7
665
4571
H52.1
ICD-10 Finland
Myopia
9.0
21.3
45
51
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
6.8
21.1
53
79
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.1
20.9
82
204
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
4.0
20.8
84
214
H3603, E103
ICD-10 Finland
NA
7.4
20.7
49
67
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.5
20.6
164
676
3503
FHL
Single muscle retroposition
211.7
20.6
21
*
L03AB07
ATC
interferon beta-1a; parenteral
12.6
20.3
36
29
A10AA01
ATC
NA
3.7
20.0
88
242
H51.2
ICD-10 Finland
Internuclear ophthalmoplegia
+∞
19.8
19
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
3.9
19.6
82
216
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
19.6
569
3839
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.4
19.5
72
169
N02BE01
ATC
paracetamol; systemic, rectal
1.6
19.5
1980
17775
H3601, E113
ICD-10 Finland
NA
4.8
19.5
65
138
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
2.2
19.4
208
992
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
3.3
19.3
99
309
A10AE05
ATC
insulin detemir; parenteral
2.5
19.1
154
640
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
19.0
670
4741
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
5.5
18.9
56
104
H52.2
ICD-10 Finland
Astigmatism
12.8
18.9
33
26
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
9.6
18.8
38
40
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.0
18.7
75
191
T90.5
ICD-10 Finland
Sequelae of intracranial injury
5.9
18.6
52
90
H50.4
ICD-10 Finland
Other and unspecified heterotropia
191.4
18.6
19
*
ZXA10
NOMESCO Finland
Bilateral
1.7
18.5
435
2764
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
18.4
574
3937
C10AA01
ATC
simvastatin; oral
1.5
18.2
1035
8137
CEC80
NOMESCO Finland
Partial transposition of extraocular muscle
+∞
17.7
17
*
SPAT1301
SPAT
No procedures
1.5
17.7
741
5441
H46
ICD-10 Finland
Optic neuritis
8.6
17.7
38
45
T89
ICPC
Diabetes insulin dependent
3.0
17.2
100
341
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.7
17.1
371
2294
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
4.6
17.0
59
131
C08CA01
ATC
amlodipine; oral
1.5
17.0
830
6292
D32.9
ICD-10 Finland
Benign neoplasm: Meninges, unspecified
10.8
16.9
32
30
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
16.8
1348
11273
C10AA05
ATC
atorvastatin; oral
1.5
16.8
880
6767
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
6.5
16.7
43
67
F05
ICPC
Visual disturbance other
3.3
16.7
85
264
CKC12
NOMESCO Finland
Photocoagulation of retina
2.7
16.7
115
436
CEC20
NOMESCO Finland
Recession and advancement of extraocular muscle
+∞
16.7
16
*
37300
ICD-8 Finland
Strabismus, Concomitans convergens
+∞
16.7
16
*
S06.2
ICD-10 Finland
Diffuse brain injury
5.3
16.5
50
96
WX140
NOMESCO Finland
Parabulbar anesthesy
2.6
16.4
121
478
H52.3
ICD-10 Finland
Anisometropia and aniseikonia
21.1
16.0
23
11
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
4.8
15.9
53
113
H47.1
ICD-10 Finland
Papilloedema, unspecified
10.1
15.9
31
31
N86
ICPC
Multiple sclerosis
9.5
15.9
32
34
H36.01
ICD-10 Finland
Diabetic maculopathy
4.9
15.9
52
109
XA800
NOMESCO Finland
Neuropsychological investigation
2.8
15.7
105
391
A28
ICPC
Limited function/disability NOS
1.7
15.6
365
2303
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
15.6
694
5139
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.6
15.6
116
462
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.2
15.5
82
263
J01DB01
ATC
cefalexin; oral
1.5
15.4
1823
16297
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
3.0
15.2
88
300
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
5.1
15.2
47
93
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.8
15.1
63
167
H3601, E103
ICD-10 Finland
NA
6.0
15.1
41
69
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
5.5
15.1
44
81
H3603, E113
ICD-10 Finland
NA
5.2
14.8
45
87
SPAT1229
SPAT
Assessment of need for aid
1.9
14.4
212
1153
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
5.6
14.3
41
74
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
14.2
389
2560
S06.3
ICD-10 Finland
Focal brain injury
4.3
14.2
52
123
SPAT1262
SPAT
Handing over of treatment supplies
1.6
14.1
432
2928
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
4.0
14.0
56
144
XCD10
NOMESCO Finland
Electrophysiological examination of eye
3.2
13.9
73
234
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
7.8
13.8
31
40
N03AX16
ATC
pregabalin; oral
1.5
13.7
508
3596
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.1
13.7
53
132
H47.2
ICD-10 Finland
Optic atrophy
9.7
13.7
27
28
SPAT1263
SPAT
Sampling
1.4
13.4
924
7393
H53.4
ICD-10 Finland
Visual field defects
3.4
13.4
65
197
AA1BD
NOMESCO Finland
Extensive CT of head and brain
2.9
13.3
82
291
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
5.6
13.3
38
69
H52.0
ICD-10 Finland
Hypermetropia
8.6
13.2
28
33
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.5
13.2
61
178
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.6
13.1
58
163
AAE10
NOMESCO Finland
Transsphenoidal total or partial excision of intracranial lesion
7.9
13.1
29
37
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
13.0
582
4284
L28
ICPC
Limited function/disability (L)
1.6
13.0
351
2301
H3602, E113
ICD-10 Finland
NA
16.8
13.0
20
12
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
13.0
325
2086
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
2.6
12.8
95
377
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
5.5
12.8
37
68
WX110
NOMESCO Finland
Local anesthesy
1.4
12.8
1456
12656
L04AX07
ATC
dimethyl fumarate; oral
11.6
12.8
23
20
S18
ICPC
Laceration/cut
1.4
12.8
917
7375
205
Kela drug reimbursment
Chronic hypertension
1.4
12.7
654
4946
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
9.7
12.7
25
26
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.3
12.7
38
73
N03AX12
ATC
gabapentin; oral
1.6
12.6
334
2173
T90
ICPC
Diabetes non-insulin dependent
1.5
12.6
517
3735
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
12.6
747
5803
ZXA05
NOMESCO Finland
Left side
1.5
12.6
559
4108
H50.6
ICD-10 Finland
Mechanical strabismus
+∞
12.5
12
*
AAF00
NOMESCO Finland
Ventriculostomy
6.3
12.4
32
51
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.2
12.3
46
112
D32.0
ICD-10 Finland
Benign neoplasm: Cerebral meninges
9.7
12.2
24
25
A10BA02
ATC
metformin; oral
1.4
12.0
625
4728
CKC10
NOMESCO Finland
Local photocoagulation of retina
3.4
12.0
56
165
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.8
12.0
226
1334
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
11.9
626
4747
A10BB01
ATC
glibenclamide; oral
2.2
11.9
118
545
G71.3
ICD-10 Finland
Mitochondrial myopathy, not elsewhere classified
46.9
11.9
14
*
CA1CM
NOMESCO Finland
Eye and orbita extensive MRI examination with 3 Tesla magnet
14.7
11.8
19
13
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
11.8
166
889
A02BC02
ATC
pantoprazole; systemic
1.4
11.8
1409
12263
L04AX01
ATC
azathioprine; systemic
2.4
11.7
98
418
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.9
11.6
161
857
AA4CG
NOMESCO Finland
Extensive MRI examination of sella turcica with high intensity magnet
5.8
11.6
32
56
G52.8
ICD-10 Finland
Disorders of other specified cranial nerves
65.2
11.6
13
*
353
Kela drug reimbursment
Cladribine and fingolimod
19.0
11.6
17
9
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
11.5
451
3217
SPAT1153
SPAT
Removal of sutures
1.4
11.5
716
5593
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.1
11.5
125
603
H51.9
ICD-10 Finland
Disorder of binocular movement, unspecified
+∞
11.5
11
*
3507
FHL
Retroposition and resection
+∞
11.5
11
*
37303
ICD-8 Finland
Strabismus, Heterophoria (exophoria, esophroria, hypophoria)
+∞
11.5
11
*
177
Kela drug reimbursment
Insulin glargine 300 U / ml
3.3
11.4
55
167
H02AB09
ATC
hydrocortisone; systemic
3.2
11.4
59
189
H04AA01
ATC
glucagon; nasal, parenteral
3.3
11.1
55
171
L03AX13
ATC
glatiramer acetate; parenteral
10.1
11.0
21
21
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
10.1
11.0
21
21
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
11.0
193
1116
R53
ICD-10 Finland
Malaise and fatigue
1.5
10.9
428
3049
H25.1
ICD-10 Finland
Senile nuclear cataract
1.4
10.9
558
4198
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
3.0
10.9
60
201
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.1
10.8
125
618
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
12.0
10.8
19
16
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
10.7
644
4983
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
5.2
10.7
32
62
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
10.7
163
896
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.8
10.7
172
964
H26.4
ICD-10 Finland
After-cataract
1.7
10.6
210
1258
K90
ICPC
Stroke/cerebrovascular accident
2.6
10.5
75
295
164
Kela drug reimbursment
Fingolimod
14.3
10.5
17
12
UJF32
NOMESCO Finland
Coloscopy
1.4
10.5
551
4163
3505
FHL
Single muscle resection
+∞
10.4
10
*
H49.3
ICD-10 Finland
Total (external) ophthalmoplegia
+∞
10.4
10
*
H51.8
ICD-10 Finland
Other specified disorders of binocular movement
+∞
10.4
10
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
5.4
10.4
30
56
A10AE06
ATC
insulin degludec; parenteral
2.7
10.2
68
254
H16.0
ICD-10 Finland
Corneal ulcer
2.2
10.2
100
462
N06AX11
ATC
mirtazapine; oral
1.4
10.2
635
4941
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.8
10.1
63
226
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.5
10.1
79
326
C09AA05
ATC
ramipril; oral
1.4
10.1
558
4252
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
6.9
10.1
24
35
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.7
10.0
191
1134
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
2.4
10.0
85
368
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.5
10.0
428
3103
CBJ10
NOMESCO Finland
Fascia plate sling or synthetic material for ptosis correction
40.2
10.0
12
*
H53.8
ICD-10 Finland
Other visual disturbances
4.8
9.9
32
68
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
4.0
9.9
38
96
G91.1
ICD-10 Finland
Obstructive hydrocephalus
6.7
9.9
24
36
H53.0
ICD-10 Finland
Amblyopia ex anopsia
6.3
9.8
25
40
G91.0
ICD-10 Finland
Communicating hydrocephalus
6.0
9.8
26
44
N18
ICPC
Paralysis/weakness
3.0
9.8
54
182
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
9.6
9.8
19
20
H57.1
ICD-10 Finland
Ocular pain
2.7
9.7
66
252
N29
ICPC
Neurological sympt/complt other
3.0
9.7
53
177
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
9.7
452
3331
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
9.7
371
2630
L04AA31
ATC
teriflunomide; oral
13.4
9.7
16
12
CJB10
NOMESCO Finland
Laser discission of secondary cataract
1.7
9.6
184
1091
E23.00
ICD-10 Finland
Panhypopituitarism
6.8
9.6
23
34
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
11.4
9.6
17
15
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
9.4
681
5418
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.6
9.4
239
1537
XCW11
NOMESCO Finland
Assessment of strabismus
100.4
9.4
10
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
9.4
439
3234
S04.1
ICD-10 Finland
Injury of oculomotor nerve
+∞
9.4
9
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
9.4
276
1843
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
3.4
9.4
43
127
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
5.3
9.4
27
51
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
9.3
896
7447
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
9.3
294
1997
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.1
9.3
48
155
A06AD11
ATC
lactulose; oral
1.5
9.3
315
2172
G44.2
ICD-10 Finland
Tension-type headache
1.6
9.3
248
1617
H3600, E113
ICD-10 Finland
NA
3.5
9.3
42
123
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.6
9.2
274
1831
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
9.2
182
1093
H3600, E103
ICD-10 Finland
NA
4.2
9.2
33
79
WX882
NOMESCO Finland
High dependency care
2.5
9.2
70
287
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.5
9.1
67
269
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
9.1
337
2368
N06AB10
ATC
escitalopram; oral
1.5
9.1
357
2543
N02AA05
ATC
oxycodone; systemic
1.5
9.0
322
2247
C03CA01
ATC
furosemide; systemic
1.4
9.0
648
5146
SPAT1216
SPAT
Assessment of functional ability
1.5
8.9
340
2403
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
8.9
351
2501
N03AX14
ATC
levetiracetam; systemic
2.6
8.9
64
252
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
8.9
831
6863
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
5.8
8.9
24
42
SPAT1260
SPAT
Consultation of another employee
1.5
8.9
377
2727
A10BB12
ATC
glimepiride; oral
1.7
8.8
172
1027
D32.01
ICD-10 Finland
Benign tumor of meninges on interhemispheric surface
8.6
8.8
18
21
H02AB06
ATC
prednisolone; systemic
1.3
8.8
976
8258
C09AA02
ATC
enalapril; systemic
1.4
8.8
432
3214
SPAT1234
SPAT
Support of social functional capacity
2.0
8.7
114
596
101
Kela drug reimbursment
Anterior pituitary hypofunction
5.6
8.7
24
43
ZXA00
NOMESCO Finland
Right side
1.4
8.7
569
4444
L03AB08
ATC
interferon beta-1b; parenteral
14.1
8.7
14
10
G52.9
ICD-10 Finland
Cranial nerve disorder, unspecified
50.2
8.7
10
*
H52.5
ICD-10 Finland
Disorders of accommodation
50.2
8.7
10
*
RS221
NOMESCO Finland
NA
3.5
8.6
38
109
ZXC95
NOMESCO Finland
Use of surgical navigator
3.9
8.6
34
89
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
3.2
8.6
43
136
CBH25
NOMESCO Finland
Tarsorrhaphy
16.3
8.5
13
8
C09CA01
ATC
losartan; oral
1.4
8.5
501
3845
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
27.6
8.5
11
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
1.5
8.4
280
1921
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
8.4
280
1923
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
5.7
8.4
23
41
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
8.4
322
2280
37302
ICD-8 Finland
Strabismus, Concomitans sursum sive deorsum vergens
+∞
8.3
8
*
37301
ICD-8 Finland
Strabismus, Concomitans divergens
+∞
8.3
8
*
3783A
ICD-9 Finland
Strabismus and other disorders of binocular eye movements, Other and unspecified heterotropia
+∞
8.3
8
*
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.8
8.3
128
711
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
10.8
8.3
15
14
D33.00
ICD-10 Finland
Medial pilosytic astrocytoma of the cerebrum
10.8
8.3
15
14
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
5.5
8.3
23
42
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.7
8.3
175
1071
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
9.5
8.3
16
17
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
3.3
8.3
40
124
S02.11
ICD-10 Finland
Fracture of base of skull, open
7.1
8.2
19
27
L04AA27
ATC
fingolimod; oral
14.5
8.2
13
9
K91
ICPC
Cerebrovascular disease
3.4
8.2
37
109
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
2.6
8.1
57
224
N03AF01
ATC
carbamazepine; oral, rectal
1.9
8.1
112
597
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
6.8
8.1
19
28
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
4.8
8.1
25
52
ZX120
NOMESCO Finland
Intravenous
1.6
8.0
195
1240
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
8.0
595
4739
SPAT1312
SPAT
General health counselling
1.3
8.0
651
5255
N06AX16
ATC
venlafaxine; oral
1.5
8.0
237
1584
S06.0
ICD-10 Finland
Concussion
1.6
8.0
204
1316
S02.10
ICD-10 Finland
Fracture of base of skull, closed
7.2
8.0
18
25
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.9
504
3912
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.7
7.9
51
190
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
7.9
729
5986
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
7.8
96
491
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.8
188
1193
H50.59
ICD-10 Finland
Heterophor UNS
45.1
7.7
9
*
K08.3
ICD-10 Finland
Retained dental root
1.8
7.7
139
811
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
2.6
7.7
51
195
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
5.6
7.7
21
38
G91.8
ICD-10 Finland
Other hydrocephalus
18.4
7.6
11
6
D33.39
ICD-10 Finland
Benign tumor of the cranial nerves UNS
25.1
7.6
10
*
N03AF02
ATC
oxcarbazepine; oral
2.2
7.6
69
312
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.5
7.6
289
2042
N28
ICPC
Limited function/disability (N)
3.0
7.6
40
133
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
4.0
7.6
28
70
D43.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Central nervous system, unspecified
8.9
7.5
15
17
D43.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Brain, infratentorial
10.0
7.5
14
14
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
7.5
123
697
N01
ICPC
Headache
1.7
7.5
166
1031
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
7.5
351
2581
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
7.1
7.5
17
24
G04BD09
ATC
trospium; oral
2.4
7.5
59
248
I63.8
ICD-10 Finland
Other cerebral infarction
4.0
7.5
28
71
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
3.1
7.4
39
129
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
7.4
95
493
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.6
7.4
192
1243
PA6AD
NOMESCO Finland
CT of neck arteries
3.2
7.4
36
113
N18.8
ICD-10 Finland
Other chronic renal failure
2.3
7.3
64
283
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.6
7.3
191
1239
B01AC07
ATC
dipyridamole; systemic
1.9
7.3
110
607
H51.1
ICD-10 Finland
Convergence insufficiency and excess
+∞
7.3
7
*
9530/0-C70.9
ICD-O-3
Meningioma, NOS, of meninges, NOS
9.4
7.3
14
15
L01
ICPC
Neck symptom/complaint
1.5
7.2
250
1730
J01DA01
ATC
[U] cefalexin; systemic
1.3
7.2
1305
11645
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
2.3
7.2
60
260
A10BH01
ATC
sitagliptin; oral
1.6
7.1
198
1301
J01FF01
ATC
clindamycin; systemic
1.3
7.1
530
4210
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.3
7.1
659
5404
WX002
NOMESCO Finland
Sedation and analgesia
1.4
7.1
393
2977
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
4.0
7.1
26
65
P20
ICPC
Memory disturbance
1.5
7.1
262
1842
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.5
7.0
248
1725
SPAT1310
SPAT
Counselling related to known health issue
1.3
7.0
650
5327
SPAT1215
SPAT
Assessment of need for medical rehabilitation
1.9
7.0
90
470
R13
ICD-10 Finland
Dysphagia
1.7
7.0
136
814
S02.30
ICD-10 Finland
Fracture of orbital floor, closed
4.1
7.0
25
61
R4150
NOMESCO Finland
Neuropsychological rehabilitation
4.9
7.0
21
43
M79.6
ICD-10 Finland
Pain in limb
1.3
6.9
685
5662
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.1
6.9
76
371
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
6.9
218
1476
XX3DW
NOMESCO Finland
Time consuming IT work
1.5
6.9
205
1371
C01DA14
ATC
isosorbide mononitrate; oral
1.4
6.9
341
2531
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
5.2
6.9
20
39
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
6.9
793
6684
H57.0
ICD-10 Finland
Anomalies of pupillary function
5.8
6.9
18
31
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
13.8
6.9
11
8
N05CF01
ATC
zopiclone; oral
1.3
6.8
658
5417
G47.3
ICD-10 Finland
Sleep apnoea
1.4
6.8
397
3033
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.8
1083
9494
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
1.8
6.8
106
593
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.9
6.8
98
533
R11
ICD-10 Finland
Nausea and vomiting
1.6
6.8
154
964
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
2.4
6.8
52
217
H50.50
ICD-10 Finland
Alternating hyperphoria
40.2
6.8
8
*
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
6.8
299
2177
H25.8
ICD-10 Finland
Other senile cataract
1.5
6.7
227
1562
M31.5
ICD-10 Finland
Giant cell arteritis with polymyalgia rheumatica
3.2
6.7
32
100
V03AE01
ATC
polystyrene sulfonate; oral
3.2
6.7
32
100
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
3.2
6.7
32
100
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.5
6.7
203
1365
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
6.4
6.6
16
25
H25.0
ICD-10 Finland
Senile incipient cataract
1.7
6.6
124
734
N06AA09
ATC
amitriptyline; systemic
1.5
6.6
191
1271
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
3.4
6.6
29
85
W19
ICD-10 Finland
Unspecified fall
1.6
6.6
183
1204
L76
ICPC
Fracture: other
2.3
6.6
57
253
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.3
6.6
31
96
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.2
6.6
61
277
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
2.6
6.6
44
171
GEC24
NOMESCO Finland
Thoracoscopic thymectomy
8.7
6.5
13
15
D33.30
ICD-10 Finland
Acoustic neuroma
4.1
6.5
23
56
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.6
6.5
27
76
NHQ40
NOMESCO Finland
Amputation of toe
2.7
6.5
42
159
TCE00
NOMESCO Finland
Therapeutic injection into extraocular muscle
70.0
6.4
7
*
D33.11
ICD-10 Finland
Brain stem
70.0
6.4
7
*
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
7.4
6.4
14
19
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
6.3
211
1451
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.5
6.3
233
1635
WX872
NOMESCO Finland
Intensive care
1.8
6.3
107
617
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.0
6.3
74
376
D32.07
ICD-10 Finland
Secondary or multiple benign tumor of the meninges below the exam
18.1
6.3
9
5
CA1BM
NOMESCO Finland
Eye and orbita MRI examination with 3 Tesla magnet
+∞
6.3
6
*
CEC85
NOMESCO Finland
Combined correction of cyclodeviation
+∞
6.3
6
*
D33.37
ICD-10 Finland
Another benign tumor of the cranial nerves
26.7
6.2
8
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
4.8
6.2
19
40
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
6.2
531
4295
G04CA02
ATC
tamsulosin; oral
1.3
6.2
500
4010
M03BX01
ATC
baclofen; systemic
2.8
6.2
36
128
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
5.0
6.2
18
36
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
6.2
675
5640
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
6.3
6.2
15
24
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
2.4
6.1
47
195
N03AG01
ATC
valproic acid; systemic, rectal
1.8
6.1
106
616
AA5PD
NOMESCO Finland
CT examination of brain pefusion
4.0
6.1
22
55
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
2.7
6.1
38
143
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
6.7
6.0
14
21
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
161
117
14.58
176.03
1.1
1.1
3.1
5.4
nmol/l
0.47
33
25
241
510
5.09
107.94
1.5
1.4
573.5
545.5
mg/l
0.17
235
481
1169
6779
2.29
91.46
2.3
2.1
143.2
225.4
u/l
4.48
1118
6352
207
457
4.83
87.85
1.4
1.3
3.8
3.8
mmol/l
0.13
200
427
205
456
4.79
86.19
1.6
1.5
21.0
28.6
e6/l
0.20
163
351
205
456
4.79
86.19
1.7
1.6
825.6
796.5
e6/l
0.02
170
371
106
134
8.20
78.67
1.2
1.2
60.0
41.5
mg/l
0.53
78
110
95
105
9.34
78.42
1.1
1.1
1.1
1.1
u/l
0.38
52
52
103
128
8.33
77.52
1.1
1.1
—
—
—
0
0
101
128
8.16
74.78
1.1
1.1
366.2
282.7
mg/l
0.33
79
107
124
218
5.92
67.72
1.1
1.0
—
—
—
0
0
112
185
6.27
65.15
1.1
1.0
—
—
—
0
0
667
3534
2.18
60.40
1.9
2.1
28.9
30.0
s
4.81
636
3431
334
1372
2.64
53.33
2.4
2.4
11.0
24.6
au/ml
—
8
65
312
1243
2.71
52.93
1.3
1.3
87.8
54.5
au/ml
—
5
54
100
196
5.26
48.52
2.0
1.6
—
—
—
0
0
1708
13073
1.85
48.50
6.3
4.8
7.0
6.8
mmol/l
4.60
1619
12275
84
146
5.91
46.37
1.5
1.2
1.9
2.0
mmol/l
0.55
77
136
1210
8659
1.73
40.29
4.6
3.8
40.7
54.9
ng/l
0.97
926
6194
1334
10115
1.64
33.35
8.0
6.0
1.2
1.2
mmol/l
0.51
1218
9144
1433
11101
1.63
32.52
8.7
6.9
1.2
1.2
mmol/l
0.07
1202
9381
455
2650
1.86
29.22
8.0
7.3
1.3
1.1
mmol/l
0.38
354
2058
453
2654
1.85
28.49
8.0
7.3
5.1
5.1
kpa
0.04
426
2527
453
2655
1.85
28.45
8.0
7.2
12.3
12.1
kpa
0.27
428
2529
1260
9671
1.57
28.15
5.5
4.8
35.0
35.1
g/l
0.43
1183
8976
52
97
5.45
26.67
1.8
1.8
—
—
—
0
0
1734
14443
1.57
26.04
5.8
4.6
480.2
1497.6
e6/l
1.11
31
217
299
1576
2.01
25.67
2.8
2.8
9.9
10.7
g/l
2.73
264
1433
801
5692
1.58
24.06
5.1
4.1
0.0
0.0
estimate
1.28
252
1897
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
54
115
4.77
23.85
1.1
1.1
—
—
—
0
0
1869
15978
1.56
23.74
4.7
4.0
13.2
12.8
mm/h
0.68
1732
14731
43
78
5.59
22.74
1.1
1.1
1165.7
332.7
ng/l
—
9
19
51
109
4.75
22.44
1.2
1.1
—
—
—
0
0
189
890
2.21
21.75
1.8
1.8
35.6
38.9
u/l
1.39
166
778
367
2183
1.79
21.55
8.9
8.1
120.4
121.1
g/l
0.25
355
2100
1303
10478
1.47
21.01
4.6
3.7
0.0
0.0
estimate
0.00
256
1959
1317
10616
1.47
20.95
4.7
3.8
0.0
0.0
estimate
0.21
251
1918
25
27
9.34
20.87
1.1
1.2
—
—
—
0
0
464
2986
1.67
20.45
7.1
6.0
1.1
1.0
mmol/l
1.18
433
2770
1039
8040
1.48
20.08
5.0
4.0
—
—
—
0
0
32
49
6.60
20.02
1.1
1.2
—
—
—
0
0
1296
10481
1.46
19.87
6.0
5.1
0.0
0.0
estimate
0.50
262
1987
76
237
3.27
19.85
1.1
1.1
—
—
—
0
0
1402
11520
1.46
19.70
6.5
6.2
10.8
11.8
umol/l
2.54
1328
10912
260
1437
1.90
19.26
10.1
7.0
25.0
24.5
mmol/l
1.65
242
1337
2168
19491
1.59
19.14
5.3
4.7
1.9
2.1
mu/l
0.94
1979
17677
2408
22254
1.82
19.02
24.0
17.7
139.6
139.6
mmol/l
0.65
2358
21667
34
59
5.82
18.84
1.0
1.1
—
—
—
0
0
2410
22312
1.80
18.45
24.1
17.8
4.0
4.0
mmol/l
0.25
2352
21691
2338
21466
1.70
18.39
20.2
15.2
22.6
25.0
mg/l
3.25
1938
17144
24
29
8.34
18.39
1.1
1.2
—
—
—
0
0
1845
16099
1.47
18.09
4.5
3.9
15.1
14.8
pmol/l
4.07
1668
14512
547
3773
1.57
17.90
1.9
1.8
—
—
—
0
0
51
133
3.89
17.43
1.9
1.9
—
—
—
0
0
33
60
5.56
17.43
1.0
1.1
—
—
—
0
0
1494
12584
1.42
17.37
10.0
9.0
4.4
4.2
e9/l
2.03
1329
10946
661
4792
1.50
17.09
3.1
2.6
4.3
5.4
e6/l
2.02
588
4217
1910
16856
1.46
17.02
8.8
7.6
81.5
78.8
u/l
1.03
1789
15840
34
65
5.29
17.02
1.3
1.1
—
—
—
0
0
439
2911
1.61
16.92
7.5
6.7
104.2
104.3
mmol/l
0.24
427
2836
637
4601
1.50
16.72
5.2
4.2
1.0
1.0
kg/l
0.08
92
676
424
2798
1.61
16.65
9.4
7.3
—
—
—
0
0
30
53
5.71
16.33
1.1
1.1
—
—
—
0
0
336
2103
1.68
16.23
8.2
7.4
9.9
10.2
mmol/l
0.33
318
1998
33
65
5.13
15.99
1.1
1.1
—
—
—
0
0
312
1942
1.69
15.36
2.8
2.1
354.7
374.8
nmol/l
1.12
288
1765
18
19
9.53
15.22
1.0
1.1
—
—
—
0
0
1250
10356
1.39
15.13
4.8
4.1
—
—
—
0
0
308
1926
1.68
14.88
2.4
2.7
66.6
66.3
g/l
0.29
278
1771
143
702
2.10
14.82
6.2
4.1
3.9
3.9
mmol/l
0.30
135
648
32
66
4.90
14.73
1.1
1.1
—
—
—
0
0
36
83
4.38
14.51
1.1
1.2
—
—
—
0
0
597
4371
1.47
14.35
1.8
1.8
1186.9
1175.9
nmol/l
0.10
466
3302
863
6821
1.39
13.42
3.3
3.1
1497.0
1593.2
ng/l
0.25
739
5847
22
35
6.33
13.28
1.1
1.1
—
—
—
0
0
801
6261
1.40
13.28
3.7
3.2
0.3
0.5
e6/l
1.88
643
4774
387
2629
1.55
13.23
1.8
1.7
—
—
—
0
0
386
2624
1.55
13.15
1.8
1.8
—
—
—
0
0
2156
19785
1.46
13.14
7.7
6.0
42.7
40.2
mmol/mol
17.97
1961
18195
16
18
8.94
12.89
2.7
1.9
—
—
—
0
0
1208
10164
1.34
12.32
7.6
6.0
2.9
2.8
%
0.78
1128
9454
171
956
1.84
12.19
1.9
1.9
3.9
2.2
ug/l
0.49
143
843
855
6849
1.36
11.93
3.1
2.5
56.0
57.8
u/l
0.24
781
6317
103
485
2.17
11.93
1.6
1.8
3.3
4.8
iu/l
0.92
39
162
878
7064
1.36
11.91
4.7
4.0
14.2
8.8
mg/mmol
1.81
586
4508
16
20
8.04
11.88
1.1
1.2
—
—
—
0
0
499
3653
1.45
11.75
3.4
3.3
0.8
0.8
mmol/l
0.58
463
3418
15
18
8.37
11.49
1.0
1.0
—
—
—
0
0
733
5777
1.37
11.20
2.4
2.2
3.2
3.0
mg/l
1.03
649
4884
309
2070
1.56
11.16
2.6
2.4
7.7
7.2
ug/l
0.09
264
1820
63
246
2.60
11.12
1.3
1.6
—
—
—
0
0
867
7029
1.35
10.99
3.7
3.2
7.3
7.5
mmol/l
0.89
710
5885
27
62
4.39
10.97
1.1
1.1
—
—
—
0
0
201
1229
1.69
10.53
8.8
9.3
24.4
24.3
mmol/l
0.24
187
1154
302
2041
1.54
10.47
7.2
6.9
1.4
1.4
mmol/l
0.36
289
1969
1205
10302
1.31
10.33
7.5
5.9
58.3
57.8
%
0.75
1124
9627
1223
10477
1.31
10.33
7.7
6.1
26.4
27.2
%
1.53
1142
9735
1049
8807
1.31
10.24
2.5
2.2
76.4
77.6
nmol/l
0.66
943
7823
114
593
1.96
10.15
1.5
1.5
1.2
1.2
g/l
1.15
109
562
420
3054
1.45
10.14
3.2
2.6
22.1
22.9
%
0.51
349
2615
216
1362
1.64
10.05
1.6
1.5
—
—
—
0
0
474
3529
1.42
10.04
3.1
2.5
12.3
12.9
umol/l
0.86
436
3265
188
1146
1.69
9.97
4.4
3.3
25.2
25.2
mmol/l
0.04
182
1106
1093
9263
1.30
9.84
2.1
2.0
94.8
93.9
pmol/l
0.25
555
4863
690
5479
1.35
9.84
2.6
2.4
—
—
—
0
0
107
553
1.97
9.72
1.9
1.9
11.0
11.6
mg/l
0.27
100
504
57
229
2.52
9.54
1.3
1.6
—
—
—
0
0
15
23
6.55
9.35
1.2
1.2
—
—
—
0
0
37
119
3.14
9.34
1.1
1.2
—
—
—
0
0
438
3257
1.41
9.29
3.1
2.5
2.2
2.3
g/l
1.70
404
3009
314
2198
1.49
9.19
4.8
3.8
2.1
1.9
mmol/l
0.46
255
1744
15
24
6.28
8.99
1.3
1.2
48.4
43.1
%
—
9
9
2392
22751
1.48
8.89
13.3
10.6
26.0
26.0
u/l
0.03
2294
21905
611
4836
1.34
8.76
1.7
1.7
20641734.3
30610120.3
pmol/l
0.19
499
4002
41
149
2.78
8.39
2.7
2.2
761.9
702.6
e6/l
0.22
20
62
128
736
1.78
8.39
1.2
1.2
1.0
0.6
u/ml
0.20
17
65
310
2204
1.46
8.37
4.6
3.7
5.9
5.8
kpa
0.18
297
2133
15
26
5.80
8.33
1.1
1.0
—
—
—
0
0
896
7521
1.29
8.30
3.2
3.4
2.4
2.4
mmol/l
0.15
767
6528
126
724
1.78
8.28
1.6
1.5
431.4
245.3
titre
—
7
30
103
556
1.89
8.27
2.8
2.3
137.3
112.1
ug/min
0.27
61
341
12
17
7.09
7.99
1.1
1.1
—
—
—
0
0
247
1696
1.50
7.93
4.4
3.9
111.2
92.5
ng/l
0.91
218
1467
1053
9078
1.26
7.70
3.2
2.8
162.5
136.8
ug/l
1.34
971
8338
259
1808
1.48
7.67
4.0
3.1
4.5
4.6
kpa
0.17
244
1747
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
135
810
1.70
7.64
2.5
2.9
0.3
0.3
u/ml
0.14
67
464
44
175
2.54
7.58
2.4
2.2
648.2
629.1
ml
0.13
29
111
102
567
1.83
7.51
2.3
1.6
390.2
306.2
mu/l
0.91
94
519
15
29
5.20
7.45
1.1
1.2
—
—
—
0
0
1512
13637
1.25
7.29
3.7
3.1
58.7
51.5
u/l
1.31
1389
12621
131
790
1.69
7.29
2.0
2.3
274.5
500.1
ug/l
1.58
126
744
148
927
1.63
7.13
6.7
5.3
1.7
1.6
%
0.32
138
862
591
4783
1.30
7.06
1.8
1.7
1.4
1.3
mg/l
0.15
458
3692
489
3860
1.33
6.99
3.2
2.8
1.3
1.2
e6/l
0.12
307
2218
2197
20777
1.32
6.90
5.2
4.7
6.3
6.0
mmol/l
8.65
1985
18765
94
533
1.79
6.53
1.5
1.6
—
—
—
0
0
2457
23702
1.45
6.35
29.9
22.3
249.2
246.9
e9/l
0.95
2403
23049
2127
20090
1.29
6.31
4.6
4.0
1.3
1.3
mmol/l
1.55
1920
18223
75
402
1.89
6.24
1.5
1.7
—
—
—
0
0
108
647
1.70
6.21
1.9
1.7
—
—
—
0
0
205
1426
1.47
6.20
4.3
3.2
127.8
128.4
g/l
0.15
200
1383
2457
23715
1.44
6.19
29.9
22.3
4.5
4.5
e12/l
0.48
2396
22970
2457
23720
1.44
6.14
29.9
22.3
7.0
6.8
e9/l
3.55
2395
22973
183
1247
1.50
6.13
10.2
9.9
—
—
—
0
0
2457
23723
1.43
6.10
30.1
22.4
133.6
134.8
g/l
3.31
2424
23338
99
1624
0.59
6.10
1.6
1.8
—
—
—
0
0
104
622
1.70
6.02
1.7
1.6
0.2
11.1
iu/ml
0.57
27
122
24
79
3.06
5.92
1.0
1.1
1536.5
1604.6
miu/ml
0.08
24
79
347
2673
1.34
5.82
4.4
4.1
240.6
244.4
u/l
0.22
330
2532
119
746
1.62
5.77
2.6
3.6
37.6
65.9
mg/l
0.90
99
612
530
4340
1.28
5.66
1.3
1.2
1.2
1.5
u/ml
0.46
149
1117
249
1828
1.40
5.64
5.2
4.0
1.2
1.2
mmol/l
0.16
222
1582
93
550
1.72
5.63
1.5
1.6
—
—
—
0
0
243
1777
1.40
5.63
2.7
2.7
62.4
64.7
ml/min/173m2
0.43
115
722
2198
20928
1.28
5.58
5.1
4.5
4.4
4.6
mmol/l
10.09
2007
19260
2182
20759
1.28
5.56
5.0
4.4
1.4
1.4
mmol/l
2.05
1984
18971
157
1060
1.51
5.52
3.6
2.6
0.7
0.7
%
0.68
152
1018
100
610
1.66
5.41
2.0
1.7
—
—
—
0
0
80
459
1.77
5.40
2.9
1.8
0.7
0.9
nmol/l
1.84
62
373
117
746
1.59
5.32
2.7
3.6
51.8
57.9
mg/l
0.26
96
610
20
63
3.19
5.31
4.0
2.2
—
—
—
0
0
69
381
1.83
5.29
1.3
1.5
—
—
—
0
0
114
725
1.60
5.24
2.7
3.5
1.5
1.8
ratio
0.53
12
60
2237
21392
1.28
5.17
5.7
5.0
2.5
2.7
mmol/l
10.78
2042
19561
345
2705
1.32
5.11
3.0
2.6
1.8
1.8
%
0.54
306
2382
198
1423
1.42
5.08
3.6
3.7
1.9
1.8
mmol/l
0.14
150
1046
83
493
1.71
4.99
2.7
2.9
33.8
35.5
umol/l
0.18
72
412
109
696
1.59
4.95
1.4
1.3
—
—
—
0
0
93
571
1.65
4.94
1.7
1.6
—
—
—
0
0
61
332
1.86
4.92
1.3
1.4
—
—
—
0
0
28
112
2.52
4.87
1.1
1.2
1.1
1.0
ratio
—
6
43
40
189
2.13
4.79
1.0
1.1
—
—
—
0
0
632
5374
1.23
4.77
1.6
1.6
21.5
20.2
nmol/l
0.64
547
4564
309
2410
1.32
4.75
4.1
3.5
—
—
—
0
0
35
157
2.25
4.75
2.2
2.3
11.5
13.8
%
0.67
15
72
130
874
1.51
4.71
1.7
1.8
—
—
—
0
0
223
1667
1.37
4.56
1.8
1.6
—
—
—
0
0
204
1503
1.39
4.56
3.6
3.7
5.2
5.2
kpa
0.16
191
1393
84
515
1.65
4.52
1.1
1.1
—
—
—
0
0
8
8
10.03
4.52
1.3
1.0
—
—
—
0
0
134
920
1.48
4.41
3.7
4.0
25.1
24.8
mmol/l
0.86
123
858
43
217
2.00
4.36
3.6
2.5
—
—
—
0
0
11
26
4.24
4.35
1.5
1.9
—
—
—
0
0
502
4204
1.24
4.34
2.9
3.0
2.5
2.5
mmol/l
0.31
435
3684
192
1417
1.38
4.26
1.7
1.6
—
—
—
0
0
345
2773
1.28
4.24
4.8
4.5
32.8
32.5
%
0.16
257
1844
81
502
1.63
4.20
2.1
1.4
9.1
9.5
u/l
0.10
67
401
19
68
2.81
4.12
2.6
2.3
0.9
1.3
ug/l
0.38
19
62
72
437
1.67
4.06
6.4
5.4
421.8
723.1
iu/ml
0.39
12
64
165
1198
1.40
4.05
3.2
3.3
4.4
4.5
pmol/l
0.45
148
1043
52
291
1.80
3.91
1.3
1.5
—
—
—
0
0
32
151
2.13
3.90
2.2
2.3
—
—
—
0
0
72
446
1.63
3.78
2.9
3.5
59.1
58.3
%
0.20
72
446
521
4441
1.22
3.77
4.2
3.9
388.6
664.9
ng/l
0.47
427
3593
114
785
1.47
3.74
2.5
2.7
—
—
—
0
0
2098
20117
1.20
3.62
17.8
14.2
78.3
78.7
ml/min/173m2
0.30
1802
16618
53
306
1.75
3.61
4.5
5.1
342.3
352.9
umol/l
0.20
42
269
150
1094
1.39
3.61
1.7
1.8
1.6
1.5
g/l
0.38
128
948
69
429
1.62
3.58
2.8
3.3
4.1
4.3
e9/l
0.27
69
429
44
244
1.82
3.44
1.6
1.7
—
1370.0
—
0
8
38
201
1.90
3.44
1.1
1.2
—
—
—
0
0
89
594
1.52
3.43
4.4
3.9
1.6
1.6
mg/l
0.05
79
535
21
88
2.40
3.39
1.3
2.8
73.0
111.4
umol/l
0.86
12
54
305
2485
1.26
3.37
3.1
2.8
7.0
8.6
umol/l
1.07
264
2186
775
6909
1.17
3.34
3.5
3.2
35.2
34.8
u/l
0.07
731
6563
53
314
1.70
3.33
1.6
1.6
—
—
—
0
0
124
897
1.40
3.17
2.0
2.4
4.2
3.8
g/l
0.61
81
657
124
898
1.40
3.15
2.0
2.4
—
—
—
0
0
124
898
1.40
3.15
2.0
2.4
7.6
7.4
g/l
0.63
83
687
70
453
1.56
3.12
1.4
1.7
—
—
—
0
0
37
201
1.85
3.12
1.3
1.6
—
—
—
0
0
37
201
1.85
3.12
1.3
1.6
—
—
—
0
0
37
201
1.85
3.12
1.3
1.6
—
—
—
0
0
405
3433
1.21
3.09
1.2
1.3
33.9
37.1
iu/ml
0.14
98
1068
76
503
1.53
3.07
3.0
2.5
17.2
16.0
%
1.26
38
255
117
843
1.41
3.07
2.0
2.5
9.6
10.3
g/l
1.29
95
723
63
400
1.59
3.05
1.3
1.2
59.0
42.5
u/l
0.18
54
348
10
29
3.46
3.04
2.4
1.3
—
—
—
0
0
1336
12461
1.14
3.01
2.8
2.8
—
—
—
0
0
658
5845
1.17
2.92
3.2
2.8
2902.8
5959.8
umol/l
1.35
579
5041
24
115
2.10
2.88
1.3
1.5
4.9
8.4
u/l
1.40
16
100
19
83
2.30
2.84
1.1
1.0
—
—
—
0
0
902
8218
1.15
2.82
5.2
5.1
4.4
3.6
ug/l
0.16
794
7335
45
268
1.69
2.82
16.4
5.5
8.5
7.3
mmol/l
1.26
40
226
72
481
1.51
2.82
2.1
2.2
4151.0
3406.9
u/l
0.10
25
199
24
117
2.06
2.77
1.0
1.0
—
—
—
0
0
59
379
1.57
2.76
1.2
1.2
42.1
52.2
u/ml
—
8
33
41
240
1.72
2.74
1.2
1.3
18.2
25.3
u/l
1.25
36
194
76
521
1.47
2.65
2.2
2.2
128.2
129.0
g/l
0.09
56
384
74
510
1.46
2.52
1.2
1.2
2.9
9.2
u/ml
1.27
16
78
259
2144
1.23
2.52
2.3
2.2
0.2
0.2
g/l
0.07
235
1995
32
179
1.80
2.51
1.7
1.6
—
—
—
0
0
47
293
1.61
2.51
2.5
2.3
32.6
24.4
mg/l
0.31
11
72
75
519
1.46
2.51
1.2
1.3
—
—
—
0
0
73
503
1.46
2.49
1.2
1.2
1.3
4.0
u/ml
2.06
12
46
20
95
2.11
2.48
2.0
2.3
587.3
1329.0
u/ml
1.67
20
95
628
5624
1.15
2.47
1.8
1.6
1.4
1.4
mmol/l
0.06
519
4675
23
116
1.99
2.45
2.5
2.5
—
—
—
0
0
10
34
2.95
2.41
1.1
1.9
—
—
—
0
0
111
837
1.34
2.28
2.1
2.5
3.0
3.1
g/l
0.34
81
671
26
142
1.84
2.23
2.6
2.8
44.7
38.4
%
—
10
51
15
67
2.25
2.17
2.1
1.8
—
—
—
0
0
154
1227
1.27
2.13
1.2
1.2
174.5
156.0
iu/ml
0.21
64
440
17
81
2.11
2.12
1.4
1.2
—
—
—
0
0
8
25
3.21
2.09
1.0
1.1
—
—
—
0
0
124
964
1.30
2.08
1.9
1.9
—
—
—
0
0
59
407
1.46
2.06
1.2
1.2
1.2
5.7
u/ml
—
7
26
46
302
1.53
2.03
1.3
1.5
—
—
—
0
0
30
179
1.68
1.95
1.0
1.0
—
—
—
0
0
8
27
2.97
1.93
1.0
1.0
—
—
—
0
0
9
33
2.73
1.93
8.6
12.9
4.7
5.9
mmol/l
—
9
33
25
142
1.77
1.92
1.3
1.2
—
—
—
0
0
41
266
1.55
1.92
1.3
1.3
—
—
—
0
0
376
3305
1.16
1.91
1.2
1.2
15.1
12.3
u/ml
0.21
138
1257
25
143
1.76
1.89
1.3
1.2
—
—
—
0
0
18
331
0.54
1.88
1.4
1.5
—
—
—
0
0
14
65
2.16
1.88
1.5
1.2
—
—
—
0
0
18
93
1.94
1.85
1.4
1.8
—
—
—
0
0
18
93
1.94
1.85
1.4
1.8
—
—
—
0
0
6
17
3.53
1.83
1.0
1.1
—
—
—
0
0
140
1126
1.26
1.83
5.4
4.0
24.1
24.1
mmol/l
0.01
122
1015
92
701
1.32
1.82
2.1
2.3
37.4
37.5
g/l
0.04
78
614
39
254
1.54
1.81
1.7
1.7
—
—
—
0
0
99
763
1.31
1.81
2.2
2.6
1.2
1.2
g/l
0.00
83
671
406
3605
1.15
1.80
3.6
3.0
2.7
2.2
e6/l
0.48
224
1977
18
95
1.90
1.75
1.4
1.8
—
—
—
0
0
19
103
1.85
1.71
1.1
1.1
31.5
28.8
u/l
0.05
13
73
352
3112
1.15
1.67
1.5
1.5
—
—
—
0
0
18
98
1.84
1.61
1.3
1.2
—
—
—
0
0
12
56
2.15
1.61
1.6
1.2
—
—
—
0
0
6
20
3.00
1.58
1.0
1.1
—
—
—
0
0
80
614
1.31
1.55
3.9
3.1
24.6
24.9
mmol/l
0.29
72
534
19
107
1.78
1.54
1.2
1.4
—
—
—
0
0
21
122
1.73
1.54
1.2
1.4
0.9
1.1
nmol/l
0.41
13
90
8
33
2.43
1.53
2.3
2.1
—
—
—
0
0
709
6580
1.11
1.51
4.5
4.4
22.7
21.6
%
1.04
355
3313
86
670
1.29
1.50
2.2
2.4
0.0
0.0
g/l
1.79
78
621
25
154
1.63
1.50
1.1
1.2
—
—
—
0
0
270
2367
1.16
1.46
2.3
2.3
168.3
144.8
ug/g
0.38
202
1877
82
638
1.29
1.45
2.2
2.4
0.0
0.0
g/l
0.00
74
591
9
39
2.31
1.43
1.0
1.1
—
6.6
pmol/l
—
0
5
47
337
1.40
1.42
1.3
1.3
—
—
—
0
0
81
633
1.29
1.40
2.2
2.4
0.0
0.0
g/l
0.00
74
590
51
372
1.38
1.40
1.8
1.4
105.2
123.0
u/ml
0.62
14
73
10
46
2.18
1.40
1.0
1.1
—
—
—
0
0
65
494
1.32
1.38
1.2
1.3
—
—
—
0
0
65
494
1.32
1.38
1.2
1.3
—
—
—
0
0
350
3140
1.13
1.36
27.4
26.8
1.3
1.4
inr
0.73
39
436
25
159
1.58
1.34
1.2
1.1
—
5.0
—
0
6
9
42
2.15
1.33
1.3
1.3
—
—
—
0
0
8
34
2.36
1.29
2.3
2.1
—
—
—
0
0
26
170
1.53
1.26
1.2
1.1
—
50.1
—
0
8
37
261
1.42
1.25
1.2
1.1
—
—
—
0
0
11
56
1.97
1.22
1.1
1.2
—
—
—
0
0
88
712
1.24
1.18
2.0
1.4
25.5
28.8
iu/l
0.38
76
603
20
309
0.64
1.16
1.4
1.4
—
—
—
0
0
20
309
0.64
1.16
1.4
1.4
—
—
—
0
0
20
309
0.64
1.16
1.4
1.4
—
—
—
0
0
5
20
2.50
1.15
12.2
5.0
—
—
—
0
0
20
308
0.65
1.14
1.4
1.4
—
—
—
0
0
24
158
1.52
1.14
1.0
1.0
766.5
662.1
ng/l
0.35
13
95
24
158
1.52
1.14
1.0
1.0
33.4
46.3
ng/l
1.00
12
95
11
58
1.90
1.12
1.1
1.1
—
—
—
0
0
1974
19305
1.09
1.11
20.2
16.3
38.5
39.4
%
2.53
1202
13333
19
119
1.60
1.11
1.5
1.6
—
—
—
0
0
5
21
2.38
1.09
1.0
1.6
—
—
—
0
0
7
32
2.19
1.08
7.7
5.0
—
—
—
0
0
7
32
2.19
1.08
1.0
1.1
—
—
—
0
0
7
33
2.12
1.05
1.0
1.1
—
—
—
0
0
11
191
0.57
1.04
1.4
1.5
—
—
—
0
0
51
394
1.30
1.02
1.3
1.3
—
—
—
0
0
9
47
1.92
1.02
1.0
1.3
—
—
—
0
0
76
618
1.24
1.01
1.3
1.1
—
—
—
0
0
9
48
1.88
1.00
1.2
1.3
—
—
—
0
0
7
35
2.00
1.00
1.3
3.6
50.3
42.4
umol/l
—
7
27
18
115
1.57
0.99
2.7
3.6
—
—
—
0
0
1800
17577
1.07
0.98
23.9
18.4
13.9
13.8
%
1.74
1767
17156
45
581
0.77
0.96
1.4
1.5
—
—
—
0
0
23
157
1.47
0.96
1.0
1.0
211.1
316.4
ng/l
1.63
12
98
14
85
1.65
0.94
1.1
1.2
—
—
—
0
0
76
625
1.22
0.93
1.3
1.1
—
—
—
0
0
18
118
1.53
0.90
5.9
3.5
—
—
—
0
0
64
519
1.24
0.90
1.5
1.4
—
—
—
0
0
78
650
1.21
0.86
1.4
1.4
275.1
280.4
ug/g
0.09
49
385
18
120
1.50
0.85
1.6
1.6
—
—
—
0
0
31
231
1.35
0.83
1.7
1.5
0.2
0.3
nmol/l
0.83
25
181
18
121
1.49
0.82
1.5
1.7
—
—
—
0
0
18
121
1.49
0.82
1.5
1.7
—
—
—
0
0
18
121
1.49
0.82
1.5
1.7
—
—
—
0
0
18
121
1.49
0.82
1.5
1.7
—
—
—
0
0
6
32
1.88
0.81
1.0
1.1
106.8
94.7
%
—
6
32
6
32
1.88
0.81
1.0
1.1
—
—
—
0
0
41
320
1.29
0.80
1.1
1.2
7.0
2.5
u/ml
0.36
14
106
10
58
1.73
0.79
1.0
1.4
—
—
—
0
0
42
330
1.28
0.79
1.1
1.1
—
—
—
0
0
11
66
1.67
0.78
1.2
1.2
106.3
111.7
%
0.35
11
58
75
630
1.20
0.78
1.8
1.7
—
—
—
0
0
22
157
1.40
0.76
1.2
1.4
9.3
12.3
mmol/l
—
8
47
183
1649
1.12
0.74
2.5
2.2
11.8
12.6
nmol/l
0.54
158
1441
20
142
1.41
0.72
1.5
1.5
—
—
—
0
0
32
247
1.30
0.70
1.4
1.3
322.6
280.2
pmol/l
0.25
26
188
224
2050
1.10
0.69
2.8
2.4
44.4
61.9
u/l
0.31
182
1739
27
204
1.33
0.69
1.3
1.2
64.4
61.6
u/l
0.10
17
139
5
28
1.79
0.66
1.0
1.1
—
—
—
0
0
23
172
1.34
0.63
1.3
1.6
—
—
—
0
0
65
553
1.18
0.62
1.6
1.4
—
—
—
0
0
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
38
309
1.23
0.58
1.1
1.2
5.0
4.6
u/ml
—
9
141
35
282
1.24
0.58
1.1
1.4
—
—
—
0
0
47
392
1.20
0.57
4.8
3.5
1.0
1.5
%
1.27
38
302
33
265
1.25
0.56
1.4
1.6
58.0
62.9
%
0.27
18
165
19
252
0.75
0.56
1.6
1.7
—
—
—
0
0
62
718
0.86
0.54
1.6
1.6
3.0
3.6
mg/l
0.23
47
508
71
618
1.15
0.54
1.5
1.7
—
—
—
0
0
21
160
1.31
0.53
1.7
1.2
—
—
—
0
0
14
101
1.39
0.49
2.8
6.8
—
59.4
—
0
29
34
280
1.22
0.48
1.1
1.4
—
—
—
0
0
21
163
1.29
0.48
1.2
1.5
14.4
13.7
u/l
0.23
21
156
77
683
1.13
0.46
2.0
1.7
—
—
—
0
0
42
356
1.18
0.46
1.2
1.1
2863.9
87.9
iu/ml
0.50
12
76
24
192
1.25
0.45
1.3
1.2
—
—
—
0
0
108
981
1.11
0.44
1.1
1.1
—
—
—
0
0
33
275
1.20
0.43
1.1
1.4
—
—
—
0
0
5
31
1.61
0.43
1.2
1.4
—
—
—
0
0
55
481
1.15
0.42
1.2
1.4
—
—
—
0
0
19
149
1.28
0.41
1.1
1.5
1.4
1.3
promille
0.07
12
114
22
176
1.25
0.41
1.8
1.5
46.4
23.1
u/ml
—
5
35
48
416
1.16
0.41
1.4
1.5
81.2
223.2
pmol/l
2.57
48
410
43
370
1.16
0.41
1.4
1.3
238.7
271.2
u/ml
0.41
31
224
108
987
1.10
0.40
1.3
1.3
—
—
—
0
0
25
204
1.23
0.40
1.2
1.5
31.8
28.2
%
0.16
13
126
7
104
0.67
0.39
1.1
1.3
—
—
—
0
0
10
71
1.41
0.39
1.1
1.3
3.7
4.7
umol/l
—
10
65
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
23
280
0.82
0.38
1.4
1.5
—
—
—
0
0
20
247
0.81
0.38
1.0
1.0
2.0
2.4
u/ml
—
10
98
87
793
1.10
0.36
1.0
1.1
—
1.6
—
0
11
5
79
0.63
0.35
1.0
1.8
—
—
—
0
0
16
126
1.27
0.35
1.3
1.5
22.8
7.8
u/l
—
5
60
10
73
1.37
0.34
2.2
2.5
—
—
—
0
0
10
73
1.37
0.34
2.2
2.5
—
—
—
0
0
10
73
1.37
0.34
1.2
1.6
—
2284600.0
—
0
5
6
45
1.33
0.33
1.2
1.1
—
—
—
0
0
28
329
0.85
0.33
1.1
1.1
0.2
1.7
u/ml
3.15
12
144
32
275
1.17
0.32
1.1
1.4
—
—
—
0
0
33
381
0.86
0.32
1.5
1.5
—
—
—
0
0
10
74
1.35
0.32
1.3
1.4
—
—
—
0
0
15
119
1.26
0.31
2.7
1.6
—
—
—
0
0
15
119
1.26
0.31
2.7
1.6
—
—
—
0
0
32
276
1.16
0.31
1.1
1.4
—
—
—
0
0
17
138
1.23
0.30
1.4
1.2
—
—
—
0
0
32
278
1.15
0.29
1.1
1.4
—
—
—
0
0
34
297
1.15
0.29
1.0
1.1
—
—
—
0
0
16
131
1.22
0.27
1.4
2.1
209.2
145.5
ug/min
—
5
32
12
149
0.80
0.25
1.0
1.1
—
—
—
0
0
12
149
0.80
0.25
1.0
1.1
—
—
—
0
0
12
149
0.80
0.25
1.0
1.1
—
—
—
0
0
20
235
0.85
0.25
1.3
1.3
7.9
7.3
mmol/l
0.24
11
168
247
2377
1.04
0.24
3.5
4.1
6.3
19.2
ug/l
2.50
207
1972
12
148
0.81
0.24
1.3
1.3
0.2
0.8
u/ml
—
5
73
10
78
1.28
0.24
1.2
1.8
—
—
—
0
0
25
219
1.14
0.22
1.4
1.3
192842.9
96408.2
e6/l
0.22
17
151
12
146
0.82
0.22
1.0
1.1
—
—
—
0
0
12
146
0.82
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
2.5
—
0
11
8
101
0.79
0.21
12.1
11.2
0.6
0.6
mmol/l
—
8
93
8
103
0.78
0.21
1.1
1.4
—
—
—
0
0
8
103
0.78
0.21
1.1
1.4
—
—
—
0
0
27
240
1.13
0.20
4.4
3.4
55.2
57.4
%
0.13
17
154
162
1683
0.96
0.18
1.9
2.0
—
—
—
0
0
484
4744
1.02
0.18
2.9
3.2
0.7
0.8
ug/l
0.10
337
3237
55
512
1.08
0.18
3.3
3.1
0.8
0.8
nmol/l
0.75
40
396
22
248
0.89
0.18
3.5
3.7
—
—
—
0
0
213
2063
1.04
0.17
3.3
2.9
259.6
215.9
ng/l
0.46
192
1867
20
225
0.89
0.16
1.1
1.1
102.8
94.2
%
1.03
20
213
13
111
1.17
0.15
1.2
1.2
—
—
—
0
0
58
615
0.94
0.15
1.4
1.4
—
—
—
0
0
31
337
0.92
0.14
2.4
1.6
—
—
—
0
0
13
112
1.16
0.14
1.4
1.2
163.2
376.2
u/l
1.29
13
103
90
861
1.05
0.14
2.1
1.8
—
—
—
0
0
20
179
1.12
0.14
5.4
4.9
237.6
57.1
u/ml
—
7
55
35
325
1.08
0.13
1.4
1.6
—
—
—
0
0
9
109
0.83
0.13
1.0
1.0
—
—
—
0
0
54
514
1.05
0.11
1.5
1.5
—
—
—
0
0
18
198
0.91
0.10
1.4
1.3
—
—
—
0
0
5
44
1.14
0.10
1.0
1.1
—
—
—
0
0
5
47
1.06
0.09
1.2
1.4
—
—
—
0
0
59
566
1.04
0.09
1.3
1.2
—
—
—
0
0
20
184
1.09
0.09
2.5
2.0
25.4
11.0
umol/l
0.29
13
128
6
57
1.05
0.08
1.5
1.6
—
—
—
0
0
155
1517
1.02
0.08
1.8
1.9
—
—
—
0
0
94
967
0.97
0.08
3.2
3.3
32.7
63.0
u/ml
1.48
87
935
53
511
1.04
0.07
6.9
3.5
23.3
27.7
mg/l
0.65
30
321
49
472
1.04
0.06
2.6
3.4
66.7
882.6
u/ml
0.88
44
442
11
121
0.91
0.06
1.0
1.1
—
—
—
0
0
121
1188
1.02
0.05
1.4
1.3
150.6
205.2
u/ml
0.85
111
1098
278
2754
1.01
0.05
1.4
1.4
—
—
—
0
0
15
140
1.07
0.04
1.3
1.4
—
—
—
0
0
29
302
0.96
0.04
1.4
1.4
21286.2
1600.1
e6/l
0.51
24
221
33
318
1.04
0.04
1.1
1.1
—
—
—
0
0
55
564
0.97
0.04
1.5
1.7
5024.6
16026.6
e6/l
3.81
40
402
13
138
0.94
0.02
3.2
1.9
—
—
—
0
0
51
502
1.02
0.01
1.2
1.3
172.3
226.3
miu/ml
0.49
15
215
15
144
1.04
0.00
1.4
1.5
1.0
1.0
g/l
0.10
15
144
19
189
1.01
0.00
1.2
2.2
2.0
2.1
u/field
—
9
76
232
2321
1.00
0.00
1.6
1.8
1.5
1.5
%
0.03
190
2025
14
138
1.01
0.00
1.2
1.4
—
—
—
0
0
58
576
1.01
0.00
1.4
1.4
—
—
—
0
0
21
212
0.99
0.00
1.2
1.6
—
—
—
0
0
27
267
1.01
0.00
1.4
1.4
57775.5
91669.8
e6/l
0.39
20
163
29
287
1.01
0.00
1.1
1.1
—
—
—
0
0
85
847
1.00
0.00
2.9
3.3
100.6
5001.6
u/ml
0.87
73
724
7
79
0.89
0.00
1.1
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
59
1.02
0.00
1.5
1.4
10.7
9.2
ug/l
—
6
59
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
6
66
0.91
0.00
1.2
1.3
9.8
22.3
%
—
6
53
0
5
0.00
0.00
0.0
1.0
—
1.0
—
0
5
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
1.8
—
0
8
0
6
0.00
0.00
0.0
1.0
—
1483.0
—
0
6
6
67
0.90
0.00
1.7
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_PARASTRAB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRAB | 1.349 [1.22, 1.49] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.034 |
During the follow-up period (1.1.1998 — 31.12.2019), 1840 out of 7311 females with H7_PARASTRAB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_PARASTRAB | 1.428 [1.29, 1.58] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 2050 out of 7503 males with H7_PARASTRAB died.
Mortality risk
Mortality risk for people of age
years, who have H7_PARASTRAB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.105% | 0.282% |
| 5 | 0.75% | 1.616% |
| 10 | 1.723% | 4.105% |
| 15 | 3.265% | 8.143% |
| 20 | 5.54% | 13.415% |
Relationships between endpoints
↥Index endpoint: H7_PARASTRAB – Paralytic strabismus
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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