This is a non-core endpoint: only basic statistics are computed.
Carcinoma in situ of vagina
CD2_INSITU_VAGINA
No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleonly females |
293218 |
2. Check conditions
|
293150 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
177 |
4. Check minimum number of eventsNone |
177 |
5. Include endpointsNone |
177 |
6. Filter based on genotype QC (FinnGen only) |
171 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D07
- Name in latin
- Carcinoma in situ prostatae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of vagina
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of other and unspecified genital organs
- In situ neoplasms
- Any operation in hilmo
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 171 | 171 | - |
| Unadjusted period prevalence (%) | 0.06 | 0.06 | - |
| Median age at first event (years) | 56.88 | 56.88 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 177
- Matched controls
- 1770
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
LEB00
NOMESCO Finland
Biopsy of vagina
231.5
261.5
136
25
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
211.4
158
*
ULA02
NOMESCO Finland
Kolposcopy
152.9
180.9
166
159
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
522.6
136.3
120
7
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
33.6
125.5
136
159
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
34.8
122.1
142
185
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
1172.7
118.9
103
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
24.9
108.8
106
100
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
26.3
88.0
70
43
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
33.1
85.5
60
27
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
240.1
74.6
72
5
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
37.8
63.3
41
14
LDA10
NOMESCO Finland
Curettage of cervix uteri
15.5
57.0
58
54
N87.0
ICD-10 Finland
Mild cervical dysplasia
19.4
49.3
42
28
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
20.4
48.5
40
25
N89.0
ICD-10 Finland
Mild vaginal dysplasia
70.3
38.4
43
8
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
316.4
27.5
27
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
10.5
25.9
31
35
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
20.0
22.0
33
20
LEB10
NOMESCO Finland
Excision of lesion of vagina
87.3
21.2
23
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
+∞
18.0
17
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
3.8
17.0
110
532
D07.2
ICD-10 Finland
Carcinoma in situ: Vagina
+∞
15.9
15
*
N87.1
ICD-10 Finland
Moderate cervical dysplasia
17.1
15.4
24
16
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
39.8
14.7
18
5
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
162.9
14.7
15
*
D06BB10
ATC
imiquimod; topical
6.5
14.1
25
44
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
37.3
13.8
17
5
N90.0
ICD-10 Finland
Mild vulvar dysplasia
75.4
12.8
14
*
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
34.8
10.5
13
*
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
3.9
10.0
33
98
D07.1
ICD-10 Finland
Carcinoma in situ: Vulva
+∞
8.4
8
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
3.0
7.9
42
168
ZXC10
NOMESCO Finland
Use of laser
8.1
7.9
17
23
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
7.7
31
105
LFC00
NOMESCO Finland
Partial excision of vulva
83.4
7.5
8
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
6.7
27
91
8070/2-C52.9
ICD-O-3
Squamous cell carcinoma in situ, NOS, of vagina, NOS
+∞
6.3
6
*
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
27.8
6.3
8
*
A63.8
ICD-10 Finland
Other specified predominantly sexually transmitted diseases
27.8
6.3
8
*
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
2.3
6.0
129
945
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
76
96
13.12
61.37
3.9
1.4
—
—
—
0
0
139
447
10.83
47.86
4.3
1.5
—
—
—
0
0
41
12
43.93
33.65
5.5
1.8
—
—
—
0
0
117
692
3.04
11.20
2.8
2.4
—
—
—
0
0
61
331
2.29
5.99
2.1
2.1
—
—
—
0
0
42
200
2.44
5.50
1.7
1.9
—
—
—
0
0
80
510
2.04
5.04
4.2
3.0
2.38
2.36
mmol/l
0.40
65
453
44
224
2.28
4.92
1.7
1.7
1116.25
1212.49
nmol/l
0.30
35
173
43
219
2.27
4.80
1.8
2.0
—
—
—
0
0
81
529
1.98
4.68
2.1
1.9
99.42
101.44
pmol/l
0.15
42
263
24
96
2.74
4.44
1.7
1.5
—
—
—
0
0
27
119
2.50
4.12
1.8
1.7
—
—
—
0
0
34
168
2.27
4.04
3.2
2.3
23.88
22.18
%
0.28
29
139
9
16
5.86
3.71
3.7
2.1
—
—
—
0
0
33
167
2.20
3.70
3.7
4.3
31.88
34.15
%
0.68
24
113
86
611
1.79
3.56
6.3
4.8
1.22
1.23
mmol/l
0.41
74
563
92
668
1.79
3.53
2.8
2.2
80.76
79.24
nmol/l
0.23
79
601
107
815
1.79
3.47
5.2
3.9
6.18
6.33
mmol/l
0.44
102
749
81
574
1.76
3.33
11.5
9.5
1.20
1.12
inr
0.39
22
182
55
350
1.83
3.23
3.4
2.5
307.15
6982.28
umol/l
2.03
47
310
81
579
1.74
3.19
6.7
4.0
36.14
36.45
g/l
0.24
74
541
36
201
1.99
3.12
2.3
1.7
—
—
—
0
0
8
16
5.18
3.09
1.6
1.4
—
—
—
0
0
138
1154
1.89
3.08
5.6
4.0
15.08
10.89
mm/h
1.96
124
1059
70
489
1.71
2.95
5.3
2.8
—
—
—
0
0
18
77
2.49
2.93
1.5
1.4
—
—
—
0
0
137
1152
1.84
2.89
11.7
6.9
74.26
74.84
u/l
0.08
129
1075
32
176
2.00
2.88
5.4
5.3
—
—
—
0
0
11
33
3.48
2.86
4.3
4.4
25.46
25.35
mmol/l
0.07
11
33
13
48
2.84
2.78
1.3
1.3
6.16
2.39
u/ml
—
5
10
6
10
6.16
2.72
1.0
1.3
—
—
—
0
0
90
683
1.65
2.71
8.2
5.6
1.22
1.23
mmol/l
0.69
77
594
13
49
2.78
2.69
1.3
1.3
3.04
9.60
u/ml
—
5
13
71
508
1.66
2.69
3.3
3.2
23.85
19.13
ng/l
0.35
40
311
9
27
3.45
2.43
2.1
1.2
—
—
—
0
0
9
27
3.45
2.43
2.1
1.2
—
—
—
0
0
108
876
1.60
2.35
14.5
9.1
3.70
3.85
e9/l
0.42
98
769
54
377
1.62
2.18
4.5
3.6
22.54
6.46
mg/mmol
0.41
25
213
17
83
2.16
2.09
2.9
2.4
2.00
2.93
ug/l
0.85
12
71
5
10
5.11
2.08
1.4
1.2
438.60
759.80
e6/l
—
5
10
7
20
3.60
2.07
1.4
1.4
—
—
—
0
0
7
20
3.60
2.07
1.4
1.4
—
—
—
0
0
22
120
1.95
2.04
2.0
3.0
—
—
—
0
0
171
1612
2.79
2.01
21.3
13.0
72.13
67.71
umol/l
1.06
171
1612
159
1448
1.96
2.00
15.6
10.5
83.99
85.07
ml/min/173m2
0.23
131
1191
94
758
1.51
1.97
4.6
3.4
0.00
0.02
estimate
0.50
15
146
5
11
4.64
1.95
1.4
1.5
—
—
—
0
0
5
11
4.64
1.95
1.4
1.5
—
—
—
0
0
5
11
4.64
1.95
1.4
1.5
—
—
—
0
0
93
752
1.50
1.90
6.1
4.7
0.00
0.01
estimate
0.50
14
149
24
141
1.81
1.79
2.4
2.5
20.67
53.40
u/ml
1.09
24
135
6
18
3.41
1.76
1.0
1.2
—
—
—
0
0
34
223
1.65
1.74
4.7
2.3
1.26
1.04
e6/l
0.11
20
116
55
406
1.51
1.71
4.7
3.6
0.00
0.01
estimate
0.50
14
148
45
318
1.56
1.70
4.0
3.0
1453.45
824.14
ng/l
0.35
38
268
22
129
1.81
1.66
2.5
1.7
—
—
—
0
0
7
26
2.76
1.60
1.4
1.0
—
—
—
0
0
91
751
1.44
1.58
4.5
3.4
0.00
0.00
estimate
-0.00
17
156
51
378
1.49
1.54
4.7
2.7
0.23
0.45
e6/l
0.76
38
275
18
103
1.83
1.47
1.5
1.4
—
—
—
0
0
7
29
2.47
1.40
1.3
1.3
—
—
—
0
0
21
129
1.71
1.37
2.7
1.7
—
—
—
0
0
43
316
1.48
1.35
1.7
1.4
22.89
21.96
nmol/l
0.13
36
262
9
44
2.10
1.29
1.1
1.3
—
—
—
0
0
13
71
1.90
1.23
1.5
2.2
2424.37
5757.59
u/l
—
6
26
35
252
1.48
1.21
2.6
2.5
2.45
2.44
mmol/l
0.19
27
222
12
65
1.91
1.16
1.3
1.4
93.67
196.20
miu/ml
—
6
32
0
35
0.00
1.16
0.0
1.6
—
—
—
0
0
5
20
2.54
1.16
1.4
1.3
—
—
—
0
0
7
30
2.39
1.13
4.0
2.1
—
—
—
0
0
7
31
2.31
1.11
1.3
2.3
—
—
—
0
0
162
1532
1.68
1.10
20.6
11.4
18.35
18.77
mg/l
0.07
126
1158
12
67
1.85
1.07
1.7
1.3
—
—
—
0
0
72
601
1.33
1.06
4.9
3.4
—
—
—
0
0
11
60
1.89
1.05
3.6
4.4
24.75
25.31
mmol/l
0.20
11
60
11
61
1.86
1.01
1.9
1.7
—
—
—
0
0
28
201
1.47
0.99
5.2
2.4
5.00
4.22
e6/l
0.14
14
95
5
23
2.21
0.98
1.8
1.1
—
—
—
0
0
0
30
0.00
0.98
0.0
1.7
—
—
—
0
0
25
177
1.48
0.95
2.3
1.5
1.36
1.32
%
0.14
18
159
35
451
0.72
0.94
1.9
1.6
1.19
1.37
mmol/l
1.08
23
391
6
27
2.26
0.94
4.2
3.3
53.33
71.29
u/ml
—
6
27
10
55
1.87
0.94
8.3
2.0
—
—
—
0
0
46
365
1.35
0.94
1.5
1.5
—
—
—
0
0
11
63
1.80
0.92
2.2
1.8
—
—
—
0
0
48
391
1.31
0.82
1.3
1.3
0.75
1.91
u/ml
1.13
12
120
0
26
0.00
0.79
0.0
1.5
—
—
—
0
0
43
348
1.31
0.77
1.7
1.7
0.81
0.83
mg/l
0.04
34
264
5
24
2.11
0.75
1.2
1.7
14850.40
32909.83
e6/l
—
5
18
153
1454
1.39
0.74
4.3
3.7
1.36
1.22
mmol/l
1.98
139
1360
16
109
1.51
0.74
1.3
1.3
80.12
105.03
u/ml
0.18
16
102
5
26
1.95
0.71
1.4
1.3
—
—
—
0
0
5
26
1.95
0.71
1.2
1.3
—
—
—
0
0
12
173
0.67
0.61
1.8
1.7
—
—
—
0
0
157
1510
1.35
0.58
4.7
4.2
1.57
1.61
mmol/l
0.45
142
1423
6
37
1.64
0.56
3.8
3.1
178.53
171.03
%
—
6
37
6
39
1.56
0.53
1.3
1.2
—
—
—
0
0
10
67
1.52
0.51
1.6
1.4
—
—
—
0
0
144
1377
1.25
0.50
6.2
5.0
38.50
38.60
mmol/mol
0.05
129
1297
157
1522
1.28
0.42
4.8
4.2
4.88
4.92
mmol/l
0.22
144
1441
5
33
1.53
0.41
1.4
1.7
89.20
109.20
ug/l
—
5
28
0
15
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
5
34
1.48
0.40
1.2
1.4
—
—
—
0
0
5
34
1.48
0.40
1.2
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
134
1284
1.18
0.38
4.6
4.4
14.48
14.51
pmol/l
0.06
120
1191
110
1041
1.15
0.36
4.2
2.8
71.10
37.27
u/l
0.70
100
987
154
1496
1.23
0.35
5.0
4.1
5.73
5.73
mmol/l
0.04
141
1395
6
45
1.34
0.34
1.3
1.3
—
—
—
0
0
6
86
0.69
0.34
1.0
1.5
—
—
—
0
0
6
46
1.31
0.33
1.0
1.0
—
—
—
0
0
158
1541
1.24
0.33
5.4
4.6
2.87
2.91
mmol/l
0.24
144
1447
12
92
1.33
0.32
1.1
1.0
—
—
—
0
0
7
54
1.31
0.31
1.6
1.8
—
—
—
0
0
7
56
1.26
0.30
1.0
1.6
—
—
—
0
0
17
142
1.22
0.25
1.2
1.3
99.82
175.85
iu/ml
—
6
66
9
76
1.19
0.25
6.4
2.2
0.00
0.12
e6/l
—
9
71
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.9
—
—
—
0
0
5
43
1.17
0.21
1.6
2.8
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
1.26
—
0
7
0
14
0.00
0.20
0.0
1.1
—
100.86
—
0
14
6
50
1.21
0.20
1.0
1.4
—
—
—
0
0
6
50
1.21
0.20
1.0
1.4
—
—
—
0
0
6
50
1.21
0.20
1.0
1.4
—
—
—
0
0
6
53
1.14
0.19
1.3
1.2
—
—
—
0
0
6
53
1.14
0.19
1.3
1.2
—
—
—
0
0
7
62
1.13
0.17
3.3
2.0
0.91
1.07
%
—
7
62
25
228
1.11
0.14
3.8
3.6
163.22
114.57
ng/l
0.12
18
150
32
342
0.92
0.12
1.3
1.3
18.21
32.35
iu/ml
—
10
125
10
115
0.86
0.11
1.4
1.4
—
27.34
—
0
5
6
57
1.05
0.08
1.8
1.6
—
—
—
0
0
5
63
0.79
0.08
4.2
2.9
50.28
45.66
%
—
5
63
149
1475
1.06
0.07
5.3
5.2
1.63
1.81
mu/l
1.47
134
1378
9
101
0.89
0.06
1.2
1.4
—
—
—
0
0
14
150
0.93
0.04
2.9
1.8
290.93
370.67
nmol/l
0.83
14
141
107
1083
0.97
0.04
3.1
3.3
—
—
—
0
0
35
343
1.03
0.01
1.3
1.2
2.12
9.09
u/ml
1.93
15
138
0
7
0.00
-0.00
0.0
1.0
—
10.25
—
0
7
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
19.00
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
-0.00
0.0
1.0
—
149.50
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_VAGINA – Carcinoma in situ of vagina
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).