≡ Risteys
FG R12 + FR

Documentation Changelog GitHub Contact & Feedback
info icon

This is a non-core endpoint: only basic statistics are computed.

See its core counterpart CD2_INSITU_VAGINA_EXALLC for full statistics.

Carcinoma in situ of vagina

DOID Endpoint Browser

CD2_INSITU_VAGINA

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

  • not C3_VAGINA
293313

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D07.2&
  • Hospital discharge: ICD-9 — 2333A
  • Cause of death: ICD-10 — D07.2&
  • Cause of death: ICD-9 — 2333A
  • Cancer registry: Topography ICD-O-3 — C52
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 2

3 out of 7 registries used, show all original rules.

147

4. Check minimum number of events

None

147

5. Include endpoints

None

147

6. Filter based on genotype QC (FinnGen only)

147

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D07
Name in latin
Carcinoma in situ prostatae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 147 147 -
Unadjusted period prevalence (%) 0.05 0.05 -
Median age at first event (years) 57.50 57.50 -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
137
Matched controls
1370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
155.4
118
*
LEB00
NOMESCO Finland
Biopsy of vagina
342.8
120.7
109
15
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
931.6
108.9
93
*
ULA02
NOMESCO Finland
Kolposcopy
219.8
107.1
131
123
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
746.9
80.9
72
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
38.0
70.9
112
144
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
32.0
66.0
104
122
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
526.6
65.4
60
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
25.3
53.0
82
76
N89.0
ICD-10 Finland
Mild vaginal dysplasia
198.4
31.1
31
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
24.3
30.6
44
26
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
15.1
29.5
52
53
LDA10
NOMESCO Finland
Curettage of cervix uteri
14.6
27.6
49
50
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
30.1
20.5
27
11
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
81.9
19.3
21
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
15.1
19.1
32
27
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
17.3
17.8
28
20
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.8
17.0
90
388
LEB10
NOMESCO Finland
Excision of lesion of vagina
68.5
16.2
18
*
D07.2
ICD-10 Finland
Carcinoma in situ: Vagina
+∞
14.9
14
*
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
118.7
10.6
11
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
43.5
10.1
12
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
9.6
10.0
20
24
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
20.3
9.1
13
7
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
15.4
8.9
14
10
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
12.8
8.3
14
12
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.2
7.4
28
78
D06BB10
ATC
imiquimod; topical
7.4
7.1
16
24
N87.1
ICD-10 Finland
Moderate cervical dysplasia
7.1
6.9
16
25
N90.0
ICD-10 Finland
Mild vulvar dysplasia
17.8
6.9
10
6
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
23.9
6.8
9
*
ZXC10
NOMESCO Finland
Use of laser
10.8
6.7
12
12
LFC00
NOMESCO Finland
Partial excision of vulva
73.1
6.5
7
*
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
+∞
6.3
6
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
6.1
60
319

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: CD2_INSITU_VAGINA – Carcinoma in situ of vagina

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).