This is a non-core endpoint: only basic statistics are computed.
See its core counterpart CD2_INSITU_VAGINA_EXALLC for full statistics.
Carcinoma in situ of vagina
CD2_INSITU_VAGINA
No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditions
|
293313 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
3 out of 7 registries used, show all original rules. |
147 |
4. Check minimum number of eventsNone |
147 |
5. Include endpointsNone |
147 |
6. Filter based on genotype QC (FinnGen only) |
147 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
- Parent code in ICD-10
- D07
- Name in latin
- Carcinoma in situ prostatae
Similar endpoints
↥List of similar endpoints to
Carcinoma in situ of vagina
based on the number of shared cases.
Similar with more cases:
- Carcinoma in situ of vagina
- Carcinoma in situ of other and unspecified genital organs
- Carcinoma in situ of other and unspecified genital organs
- In situ neoplasms
- In situ neoplasms
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 147 | 147 | - |
| Unadjusted period prevalence (%) | 0.05 | 0.05 | - |
| Median age at first event (years) | 57.50 | 57.50 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 137
- Matched controls
- 1370
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
8077/2-C52.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vagina, NOS
+∞
155.4
118
*
LEB00
NOMESCO Finland
Biopsy of vagina
342.8
120.7
109
15
LEB30
NOMESCO Finland
Destruction of lesion of vaginal mucosa
931.6
108.9
93
*
ULA02
NOMESCO Finland
Kolposcopy
219.8
107.1
131
123
N89.2
ICD-10 Finland
Severe vaginal dysplasia, not elsewhere classified
746.9
80.9
72
*
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
38.0
70.9
112
144
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
32.0
66.0
104
122
N89.1
ICD-10 Finland
Moderate vaginal dysplasia
526.6
65.4
60
*
LDA20
NOMESCO Finland
Biopsy of vaginal cervix
25.3
53.0
82
76
N89.0
ICD-10 Finland
Mild vaginal dysplasia
198.4
31.1
31
*
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
24.3
30.6
44
26
LDC03
NOMESCO Finland
Conisation of cervix uteri using diathermy or laser
15.1
29.5
52
53
LDA10
NOMESCO Finland
Curettage of cervix uteri
14.6
27.6
49
50
8077/2-C53.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of cervix uteri
30.1
20.5
27
11
N90.2
ICD-10 Finland
Severe vulvar dysplasia, not elsewhere classified
81.9
19.3
21
*
N87.0
ICD-10 Finland
Mild cervical dysplasia
15.1
19.1
32
27
N87.2
ICD-10 Finland
Severe cervical dysplasia, not elsewhere classified
17.3
17.8
28
20
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
4.8
17.0
90
388
LEB10
NOMESCO Finland
Excision of lesion of vagina
68.5
16.2
18
*
D07.2
ICD-10 Finland
Carcinoma in situ: Vagina
+∞
14.9
14
*
8077/2-C51.9
ICD-O-3
Squamous intraepithelial neoplasia, high grade of vulva, NOS
118.7
10.6
11
*
N90.1
ICD-10 Finland
Moderate vulvar dysplasia
43.5
10.1
12
*
A63.0
ICD-10 Finland
Anogenital (venereal) warts
9.6
10.0
20
24
R87.5
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal microbiological findings
20.3
9.1
13
7
LDB20
NOMESCO Finland
Electrocoagulation or laser therapy of cervix uteri
15.4
8.9
14
10
LFB10
NOMESCO Finland
Excision of lesion of vulva or perineum
12.8
8.3
14
12
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
4.2
7.4
28
78
D06BB10
ATC
imiquimod; topical
7.4
7.1
16
24
N87.1
ICD-10 Finland
Moderate cervical dysplasia
7.1
6.9
16
25
N90.0
ICD-10 Finland
Mild vulvar dysplasia
17.8
6.9
10
6
LFB20
NOMESCO Finland
Destruction of lesion of vulva or perineum
23.9
6.8
9
*
ZXC10
NOMESCO Finland
Use of laser
10.8
6.7
12
12
LFC00
NOMESCO Finland
Partial excision of vulva
73.1
6.5
7
*
R87.7
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal histological findings
+∞
6.3
6
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.6
6.1
60
319
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
61
73
13.57
51.19
4.2
1.4
—
—
—
0
0
116
351
11.93
43.46
4.4
1.5
—
—
—
0
0
33
9
46.69
27.55
5.9
2.0
—
—
—
0
0
98
579
3.08
9.54
4.6
3.8
—
—
—
0
0
71
424
2.30
5.77
4.4
2.9
2.4
2.4
mmol/l
0.30
55
369
53
279
2.41
5.76
2.1
2.0
—
—
—
0
0
30
137
2.49
4.33
3.3
2.2
25.6
22.0
%
0.67
25
110
37
190
2.27
4.11
1.7
1.7
1149.6
1190.4
nmol/l
0.10
28
144
31
148
2.39
4.06
1.7
1.8
—
—
—
0
0
11
28
4.17
4.06
4.3
4.0
25.5
25.1
mmol/l
0.24
11
28
76
522
1.94
3.82
6.3
4.7
1.2
1.2
mmol/l
0.76
61
475
49
289
2.04
3.81
3.6
2.6
306.7
7550.7
umol/l
1.79
41
249
32
160
2.28
3.76
1.8
1.9
—
—
—
0
0
33
168
2.24
3.72
2.1
1.7
—
—
—
0
0
62
401
1.94
3.69
5.7
2.9
—
—
—
0
0
71
490
1.87
3.40
7.3
3.8
35.9
36.2
g/l
0.22
64
456
78
559
1.84
3.28
2.8
2.2
79.3
80.1
nmol/l
0.10
65
497
29
148
2.20
3.23
3.8
4.4
32.2
34.0
%
0.41
20
98
66
454
1.82
3.13
2.1
1.9
100.9
102.8
pmol/l
0.11
32
213
7
12
6.06
3.06
3.6
2.3
—
—
—
0
0
118
979
2.04
3.00
12.2
6.8
75.6
75.5
u/l
0.01
110
909
118
979
2.04
3.00
5.3
3.9
15.8
11.1
mm/h
1.88
105
888
16
65
2.64
2.90
1.3
1.3
—
—
—
0
0
6
9
6.89
2.89
1.0
1.3
—
—
—
0
0
9
23
4.10
2.82
2.1
1.2
—
—
—
0
0
9
23
4.10
2.82
2.1
1.2
—
—
—
0
0
83
627
1.74
2.76
4.6
3.5
0.0
0.0
estimate
0.00
13
113
33
189
1.96
2.71
5.0
2.4
1.3
1.1
e6/l
0.10
19
100
82
624
1.71
2.60
6.3
4.9
0.0
0.0
estimate
0.00
12
117
18
82
2.36
2.60
1.8
1.7
—
—
—
0
0
15
64
2.50
2.48
1.6
1.6
—
—
—
0
0
92
730
1.70
2.43
14.7
9.0
3.7
3.8
e9/l
0.28
84
644
6
12
5.16
2.42
1.7
1.5
—
—
—
0
0
6
12
5.16
2.42
1.0
1.3
—
—
—
0
0
77
586
1.66
2.36
8.5
5.4
1.2
1.2
mmol/l
0.70
63
503
61
437
1.68
2.36
3.3
3.1
25.2
20.2
ng/l
0.33
36
276
80
618
1.65
2.29
4.6
3.6
0.0
0.0
estimate
0.00
13
114
21
110
2.06
2.19
2.5
1.7
—
—
—
0
0
46
316
1.66
2.05
5.2
2.8
0.3
0.5
e6/l
0.74
32
226
20
106
2.03
2.03
4.7
6.0
1.1
1.3
mmol/l
0.12
15
87
28
167
1.84
2.03
5.6
2.6
5.0
4.3
e6/l
0.12
14
80
26
152
1.86
2.00
4.7
5.7
—
—
—
0
0
86
692
1.59
1.98
5.5
3.8
6.3
6.3
mmol/l
0.17
81
635
20
111
1.93
1.79
2.6
1.7
—
—
—
0
0
47
335
1.59
1.78
4.6
3.7
0.0
0.0
estimate
0.00
12
116
132
1200
1.98
1.74
17.0
10.5
81.2
84.0
ml/min/173m2
0.63
106
989
18
102
1.87
1.53
2.2
3.1
—
—
—
0
0
6
23
2.67
1.38
4.2
3.5
53.3
80.6
u/ml
—
6
23
10
48
2.16
1.31
1.5
2.1
2909.0
9201.8
u/l
—
5
16
8
35
2.36
1.29
1.1
1.3
—
—
—
0
0
62
498
1.42
1.27
5.0
3.5
—
—
—
0
0
6
25
2.46
1.25
1.5
1.0
—
—
—
0
0
39
291
1.46
1.17
3.5
2.9
1650.0
881.1
ng/l
0.38
33
241
30
212
1.52
1.16
2.7
2.5
2.5
2.4
mmol/l
0.45
22
183
5
20
2.55
1.16
1.2
1.4
—
—
—
0
0
136
1281
1.82
1.10
21.9
11.3
19.7
19.1
mg/l
0.07
104
962
10
52
1.99
1.09
3.8
3.3
24.7
25.2
mmol/l
—
10
52
10
53
1.95
1.04
1.5
1.4
—
—
—
0
0
20
133
1.58
1.01
2.6
1.5
1.4
1.3
%
0.15
13
119
9
49
1.89
1.00
1.2
1.6
—
—
—
0
0
9
50
1.85
0.98
1.3
1.7
—
—
—
0
0
6
28
2.19
0.92
1.3
2.3
—
—
—
0
0
13
79
1.71
0.91
1.4
1.4
—
—
—
0
0
35
268
1.40
0.91
1.6
1.4
22.8
22.7
nmol/l
0.01
28
220
6
30
2.04
0.88
3.8
2.9
178.5
185.4
%
—
6
30
8
46
1.78
0.84
11.3
2.1
—
—
—
0
0
0
26
0.00
0.79
0.0
1.6
—
—
—
0
0
6
34
1.80
0.77
1.0
1.6
—
—
—
0
0
6
34
1.80
0.77
1.3
1.1
—
—
—
0
0
128
1209
1.45
0.76
4.1
3.8
1.3
1.2
mmol/l
1.32
114
1125
37
296
1.33
0.74
1.7
1.7
0.9
0.9
mg/l
0.04
28
225
5
25
2.03
0.73
1.2
1.4
—
—
—
0
0
132
1256
1.50
0.73
4.7
4.3
1.6
1.6
mmol/l
0.46
116
1176
5
26
1.95
0.71
4.2
2.0
—
—
—
0
0
36
292
1.31
0.65
1.6
1.5
—
—
—
0
0
5
29
1.75
0.64
1.2
1.2
—
—
—
0
0
32
390
0.77
0.61
1.9
1.7
1.2
1.3
mmol/l
0.80
21
334
0
21
0.00
0.60
0.0
1.5
—
—
—
0
0
39
324
1.28
0.59
1.3
1.3
0.8
1.9
u/ml
—
9
102
132
1265
1.43
0.59
4.7
4.3
4.8
4.9
mmol/l
0.38
118
1189
0
23
0.00
0.59
0.0
1.8
—
—
—
0
0
6
38
1.60
0.55
1.0
1.1
—
—
—
0
0
133
1284
1.38
0.48
5.4
4.8
2.8
2.9
mmol/l
0.29
118
1195
92
858
1.19
0.44
4.3
2.9
78.8
38.5
u/l
0.69
83
809
5
31
1.63
0.43
1.0
1.5
—
—
—
0
0
5
31
1.63
0.43
1.0
1.5
—
—
—
0
0
5
31
1.63
0.43
1.0
1.5
—
—
—
0
0
5
32
1.58
0.42
1.4
1.8
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
8
61
1.33
0.40
1.9
1.3
—
—
—
0
0
5
36
1.40
0.38
1.4
1.3
—
—
—
0
0
6
45
1.35
0.34
1.8
1.9
—
—
—
0
0
10
77
1.32
0.27
1.1
1.1
—
—
—
0
0
110
1062
1.14
0.25
4.7
4.3
14.6
14.5
pmol/l
0.10
96
979
119
1157
1.15
0.22
6.1
5.2
38.6
38.8
mmol/mol
0.06
104
1083
120
1168
1.15
0.22
21.7
12.3
38.9
39.7
%
0.49
86
872
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
11
133
0.81
0.20
1.8
1.7
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
100.0
—
0
14
31
285
1.11
0.16
1.3
1.3
1.2
10.7
u/ml
2.46
11
111
84
866
0.93
0.13
3.3
3.2
—
—
—
0
0
127
1253
1.10
0.10
4.9
4.3
5.7
5.7
mmol/l
0.02
115
1162
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
5
46
1.09
0.09
1.0
1.2
—
—
—
0
0
6
56
1.07
0.09
1.7
2.2
0.8
1.1
%
—
6
56
30
284
1.07
0.08
1.3
1.3
18.2
33.7
iu/ml
—
10
102
7
81
0.86
0.07
1.0
1.4
—
—
—
0
0
11
117
0.94
0.02
3.2
1.8
320.0
380.2
nmol/l
0.46
11
109
12
114
1.06
0.01
1.3
1.2
44.0
182.5
iu/ml
—
5
52
123
1234
0.98
0.00
5.5
5.1
1.7
1.8
mu/l
1.10
108
1144
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
5
58
0.86
0.00
1.0
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
10.3
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
19.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: CD2_INSITU_VAGINA – Carcinoma in situ of vagina
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).