Family history of mental and behavioural disorders

Z21_FAMILY_HISTORY_MENTAL_BEHAVIOURAL_DISORD

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Z81 Cause of death: ICD-10 — Z81 2 out of 7 registries used, show all original rules.	79
4. Check minimum number of events None	79
5. Include endpoints None	79
6. Filter based on genotype QC (FinnGen only)	78

Control definitions (FinnGen only)

Control exclude: Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_FAMILY_PERSONAL_HISTORY_CERTA_CONDI_INFLUENCI_HEALTH_STATUS

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Z[8-9]

NAME	Z21_FAMILY_HISTORY_MENTAL_BEHAVIOURAL_DISORD
CONTROL_EXCLUDE	Z21_PERSONS_W_POTEN_HEALTH_HAZARDS_RELATED_FAMILY_PERSONAL_HISTORY_CERTA_CONDI_INFLUENCI_HEALTH_STATUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Z81
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Z81
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Family history of mental and behavioural disorders based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	78	63	15
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	32.59	31.70	36.29

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
79: Matched controls
790

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Z31.5

ICD-10 Finland

Genetic counselling

25.9

43.8

Z81.0

ICD-10 Finland

Family history of mental retardation

+∞

37.5

Z81.8

ICD-10 Finland

Family history of other mental and behavioural disorders

+∞

31.3

Z81.3

ICD-10 Finland

Family history of other psychoactive substance abuse

+∞

6.3

Z81.1

ICD-10 Finland

Family history of alcohol abuse

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(21494429) FMR1 gene CGG repeat analysis in Blood or Tissue by Molecular genetics method

17.56

5.53

1.1

1.0

—

(3026389) Candida sp identified in Specimen by Organism specific culture

9.14

3.32

1.0

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

6.58

2.40

1.0

1.1

—

(3041096) Erythrocytes [Presence] in Urine by Automated

164

2.10

2.37

2.8

3.0

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

3.37

2.31

1.3

1.2

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

5.84

2.24

1.0

1.2

—

(3022217) INR in Platelet poor plasma by Coagulation assay

192

2.01

2.24

4.4

4.9

1.14

1.10

inr

0.16

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

222

1.93

2.09

3.1

3.4

—

(3034770) Mitochondria Ab [Titer] in Serum

4.77

1.97

2.0

1.5

—

(3031040) Bacteria [#/volume] in Urine by Automated count

418

1.92

5.1

3.8

—

59.71

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

4.37

1.85

12.6

2.6

0.78

0.76

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

121

2.00

1.81

2.0

1.6

0.98

0.83

mg/l

0.21

(3021601) Nitrite [Presence] in Urine by Test strip

304

1.81

4.3

5.0

0.00

estimate

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

171

1.88

1.77

1.8

1.7

—

(3037522) Nuclear Ab [Titer] in Serum

2.13

1.75

1.8

1.6

160.00

786.67

titre

—

(3009261) Glucose [Presence] in Urine by Test strip

311

1.75

1.62

3.0

3.6

0.00

estimate

—

(3035350) Ketones [Presence] in Urine by Test strip

311

1.75

1.62

3.0

3.5

0.00

estimate

-0.00

(3037467) Urinalysis macro (dipstick) panel - Urine

440

1.72

1.39

6.1

4.0

—

(3042936) Bacteria identified in Isolate by Culture

2.03

1.33

1.3

1.7

—

(3019832) Treponema pallidum Ab [Presence] in Serum

151

1.74

1.31

1.6

1.8

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

279

1.61

1.25

10.9

5.4

1.21

1.22

mmol/l

0.55

242

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

2.74

1.23

2.6

1.2

—

(3034274) Bile acid [Moles/volume] in Serum --fasting

2.74

1.23

4.2

2.6

4.78

3.83

umol/l

—

(3029937) Albumin [Presence] in Urine by Test strip

155

1.68

1.19

2.9

3.7

0.00

estimate

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

614

1.98

1.19

14.9

9.5

139.55

139.66

mmol/l

0.19

596

(3025941) Bacteria identified in Stool by Culture

2.46

1.15

1.6

1.2

—

(3002173) Hemoglobin [Mass/volume] in Arterial blood

2.46

1.15

7.4

7.3

121.71

121.53

g/l

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

219

1.60

1.14

1.9

2.0

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

2.30

1.11

2.9

2.4

—

(3016502) Oxygen saturation in Arterial blood

2.30

1.11

7.7

7.1

95.83

96.35

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.77

1.10

1.5

1.4

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

619

1.91

1.08

14.9

9.4

3.88

3.90

mmol/l

0.24

597

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.76

0.99

2.0

1.7

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.98

0.96

1.3

1.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.87

0.96

1.5

1.4

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.84

0.91

1.8

1.5

—

(3026008) Bacteria identified in Urine by Culture

184

1.52

0.89

3.0

2.5

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

1.78

0.83

1.9

1.6

—

(40761536) Microorganisms panel - Urine sediment

1.74

0.81

1.9

3.0

—

(3007164) IgA [Mass/volume] in Serum or Plasma

189

1.47

0.78

1.3

1.4

1.75

1.93

g/l

0.26

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

2.15

0.76

1.2

1.4

—

(3023520) Reticulocytes [#/volume] in Blood

1.82

0.73

3.6

2.9

65.27

79.70

e9/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

155

1.48

0.73

4.3

2.8

14.47

24.49

ng/l

0.64

(3048929) Epstein Barr virus Ab [Presence] in Serum

1.73

0.70

2.6

1.4

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

518

1.45

0.70

6.3

4.0

14.67

14.56

pmol/l

0.12

477

(3020779) Urea [Moles/volume] in Serum or Plasma

1.69

0.69

17.9

3.4

9.67

5.91

mmol/l

—

(40761511) CBC panel - Blood by Automated count

687

1.82

0.67

15.9

8.1

—

(3019150) Specific gravity of Urine by Refractometry

140

1.47

0.66

2.4

3.2

1.01

1.02

kg/l

—

(3003694) ABO and Rh group [Type] in Blood

215

1.39

0.63

1.9

1.6

—

(40760892) CBC W Ordered Manual Differential panel - Blood

312

1.35

0.60

9.8

5.5

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.62

0.59

3.6

2.2

7489.00

7487.66

u/l

—

(3044889) 12 lead EKG panel

343

1.34

0.58

3.3

2.7

—

(3019225) pH of Specimen

1.58

0.54

4.0

3.1

—

(3022313) Gas panel - Capillary blood

1.58

0.54

8.0

6.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.58

0.54

1.5

2.7

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

192

1.36

0.54

2.0

1.8

92.20

95.84

pmol/l

0.14

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.61

0.50

1.6

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

1.57

0.50

1.4

1.5

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

1.57

0.50

1.4

1.5

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

1.57

0.50

1.4

1.5

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

1.57

0.50

1.4

1.5

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

103

1.44

0.49

1.6

1.5

—

(3008898) HLA-B27 [Presence]

1.47

0.47

1.0

1.2

—

(3002256) Pathology report gross observation

1.50

0.45

1.0

1.1

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.50

0.45

1.5

1.6

—

(3027945) Reticulocytes/100 erythrocytes in Blood

1.45

0.44

6.1

3.5

1.67

1.73

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.40

0.42

1.3

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

237

1.28

0.42

2.6

1.8

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.41

0.0

1.2

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

0.06

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.2

—

0.00

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.2

—

0.00

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.2

—

0.00

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

1.16

—

(4035726) Immunohistochemistry procedure

1.50

0.41

1.6

1.2

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.41

0.0

1.1

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.41

0.0

1.0

—

2.45

—

(3020682) Albumin/Creatinine [Ratio] in Urine

116

1.36

0.41

3.1

3.3

1.34

21.00

mg/mmol

—

(3000494) Fungus identified in Specimen by Culture

1.34

0.39

1.4

1.5

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.50

0.37

1.2

1.4

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

578

0.79

0.36

4.1

3.9

—

(3023368) Bacteria identified in Blood by Culture

100

1.36

0.36

2.8

3.1

—

(3026782) Osmolality of Urine

119

1.32

0.35

3.3

2.6

520.20

564.89

mosm/kgh2o

0.34

104

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

157

1.28

0.33

1.9

2.2

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

1.41

0.32

1.6

1.7

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.65

0.27

1.0

1.1

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

171

1.23

0.27

2.1

2.4

—

(3050129) First trimester maternal screen panel - Serum or Plasma

1.26

0.26

1.4

1.3

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

116

1.25

0.24

1.4

1.3

4.62

16.07

u/ml

—

(1761868) Lipid panel - Serum or Plasma

196

0.83

0.22

2.5

2.1

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.21

0.0

1.3

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

0.21

0.0

1.8

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3022621) pH of Urine by Test strip

1.30

0.21

2.5

2.0

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

0.00

0.21

0.0

2.5

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.24

0.20

7.3

6.4

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

1.24

0.20

1.5

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

166

1.19

0.20

1.6

1.4

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.20

0.0

1.2

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

0.00

0.20

0.0

1.4

—

0.76

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

658

1.24

0.20

15.0

9.5

13.90

19.92

mg/l

1.55

477

(3016879) Cocaine [Presence] in Urine

1.17

0.19

1.3

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.17

0.19

1.2

1.0

—

(3000850) Epithelial cells [#/volume] in Urine

129

1.20

0.18

3.3

2.4

3.19

6.51

e6/l

1.28

117

(3000991) Gas panel - Venous blood

0.74

0.17

12.6

5.6

—

(3022145) Colonoscopy Study observation

1.18

0.17

1.1

1.3

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

276

1.14

0.17

2.8

2.3

—

(40768797) Stomach Pathology biopsy report

1.16

0.17

1.3

1.2

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

138

0.85

0.14

1.8

1.6

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

210

1.13

0.14

4.4

3.1

—

(40768804) Tissue Pathology biopsy report

230

0.88

0.14

1.5

1.8

—

(3044640) Blood type and Crossmatch panel - Blood

188

0.88

0.12

2.1

1.8

—

(40758558) Short blood count panel - Blood

186

0.89

0.10

12.4

7.2

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.07

0.09

1.2

1.3

630.90

658.49

u/ml

—

(36660697) Celiac disease serology panel - Serum

1.16

0.09

1.4

1.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.12

0.09

5.0

5.4

103.83

105.11

mmol/l

—

(3000764) Benzodiazepines [Presence] in Urine

1.10

0.09

1.3

—

(3028300) Cannabinoids [Presence] in Urine

1.10

0.09

1.3

—

(3027008) Opiates [Presence] in Urine

1.10

0.09

1.3

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

1.08

0.09

3.0

5.0

2.14

1.70

ug/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

117

1.13

0.09

2.8

1.8

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.07

0.08

1.4

1.6

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

1.14

0.08

2.7

2.6

5.80

215.75

ng/l

—

(36304419) Bacteria [Presence] in Urine

183

0.91

0.07

4.9

2.9

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

527

0.96

0.01

10.7

8.2

89.17

93.47

ml/min/173m2

0.52

404

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.07

0.01

2.5

1.7

—

(3018095) Leukocytes [#/volume] in Urine

246

0.96

0.00

4.7

3.7

97.58

45.35

e6/l

0.24

164

(3013512) EKG study

128

1.02

0.00

8.3

3.0

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

133

0.97

0.00

2.0

1.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

154

0.97

0.00

3.1

3.5

—

(40767663) Brazil Nut recombinant (rBer e) 1 IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

25.50

—

(3004809) Band form neutrophils/100 leukocytes in Blood

0.00

-0.00

0.0

1.8

—

3.10

—

(3011048) Pyruvate [Moles/volume] in Blood

0.00

-0.00

0.0

1.4

—

100.80

—

(3026048) Bordetella pertussis IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

-0.00

0.0

1.2

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.00

-0.00

1.6

1.3

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.8

—

39.50

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.4

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1752.00

—

(3011648) Oxygen content in Venous blood

0.00

-0.00

0.0

2.5

—

12.77

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

-0.00

0.0

1.4

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.7

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.0

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.8

—

0.69

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3027944) Amphetamines [Presence] in Urine

0.90

-0.00

1.4

1.3

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.1

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

2.4

—

(3036180) Methadone [Presence] in Urine

0.00

-0.00

0.0

1.1

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3024928) Oxygen saturation in Venous blood

0.00

-0.00

0.0

2.3

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

6.0

—

0.86

—

(3012447) Hantavirus puumala IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

0.54

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3019230) Fractional oxyhemoglobin in Venous blood

0.00

-0.00

0.0

2.4

—

66.29

—

(3019497) Choriogonadotropin.beta subunit free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.4

—

(3048469) 10-Hydroxycarbazepine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

3.5

—

43.83

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

120.22

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

1.52

—

(40765089) Chromosome analysis panel - Blood by G-banded

0.00

-0.00

0.0

1.0

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

4.2

—

52.95

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.6

—

(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing

0.00

-0.00

0.0

1.6

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

2.0

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3035320) C reactive protein [Mass/volume] in Body fluid

0.00

-0.00

0.0

1.4

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3012544) pH of Venous blood

0.93

-0.00

14.9

3.4

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(40760847) Basement membrane Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.5

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.0

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

1.6

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.00

-0.00

1.9

2.2

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3002621) Streptococcal DNAse B [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.89

-0.00

1.7

1.5

—

(3013247) Albumin in CSF/Albumin in Serum or Plasma

0.00

-0.00

0.0

1.0

—

11.12

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: Z21_FAMILY_HISTORY_MENTAL_BEHAVIOURAL_DISORD – Family history of mental and behavioural disorders

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Family history of mental and behavioural disorders

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Family history of mental and behavioural disorders (Z21_FAMILY_HISTORY_MENTAL_BEHAVIOURAL_DISORD)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints