Sequelae of poliomyelitis

AB1_SEQULAE_POLIO

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 B91
  • Hospital discharge: ICD-9 138
  • Hospital discharge: ICD-8 04[4]
  • Cause of death: ICD-10 B91
  • Cause of death: ICD-9 138
  • Cause of death: ICD-8 04[4]

2 out of 7 registries used, show all original rules.

286

4. Check minimum number of events

None

286

5. Include endpoints

None

286

6. Filter based on genotype QC (FinnGen only)

270

Control definitions (FinnGen only)

Control exclude
AB1_SEQULEAE_OF_INFECTIONS_AND_PARASITES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 3267 1689 1520
Only index persons 2365 1316 1049
Unadjusted period prevalence (%)
Whole population 0.05 0.05 0.04
Only index persons 0.04 0.05 0.04
Median age at first event (years)
Whole population 58.93 58.69 59.11
Only index persons 57.84 57.31 58.50

-FinnGen-

Key figures

All Female Male
Number of individuals 270 127 143
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 59.52 57.81 61.04

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
286
Matched controls
2860
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
B91
ICD-10 Finland
Sequelae of poliomyelitis
4503599627370496.0
307.7
250
*
1380A
ICD-9 Finland
Late effects of acute poliomyelitis[SEQUELAE POLIOMYELITIDIS]
+∞
80.0
73
*
N70
ICPC
Poliomyelitis
+∞
59.5
55
*
04499
ICD-8 Finland
Late effects of actue poliomyelitis
+∞
57.2
53
*
L28
ICPC
Limited function/disability (L)
3.7
23.6
108
407
SPAT1229
SPAT
Assessment of need for aid
4.5
19.9
56
148
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
7.4
17.3
26
38
A28
ICPC
Limited function/disability NOS
2.7
12.8
96
456
M89.6
ICD-10 Finland
Osteopathy after poliomyelitis
+∞
11.5
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.7
10.6
71
316
S72.4
ICD-10 Finland
Fracture of lower end of femur
20.8
8.5
12
6
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.4
8.4
66
315
Z02.7
ICD-10 Finland
Issue of medical certificate
3.5
8.3
30
93
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.7
8.2
49
204
N18
ICPC
Paralysis/weakness
6.4
8.0
20
33
R5110, ,
SPAT
3.1
7.8
34
119
XG466
NOMESCO Finland
Sleep oxymetry
4.7
7.8
18
40
N03AX16
ATC
[U] pregabalin
2.2
7.4
80
434
M41.9
ICD-10 Finland
Scoliosis, unspecified
9.7
6.9
13
14
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
3.1
6.6
28
96
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.8
6.3
19
52
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.6
6.2
38
160
S82.1
ICD-10 Finland
Fracture of upper end of tibia
8.0
6.2
13
17
N03AE01
ATC
clonazepam; systemic
3.3
6.2
23
73

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
144
1073
1.69
4.54
5.6
4.4
33.50
34.90
g/l
1.87
131
997
29
139
2.21
3.58
8.4
9.1
—
—
—
0
0
49
292
1.82
3.32
5.0
4.1
19.98
43.96
ug/l
0.36
40
255
73
488
1.67
3.31
3.5
3.9
176.53
161.93
ng/l
0.04
65
424
143
1129
1.53
3.16
6.8
5.8
1.21
1.21
mmol/l
0.11
131
1017
51
316
1.75
3.03
6.3
6.8
2.07
1.14
mmol/l
1.15
44
256
154
1245
1.51
2.99
8.8
6.4
1.22
1.21
mmol/l
0.60
134
1062
50
318
1.69
2.71
6.4
6.7
5.32
5.03
kpa
1.65
45
305
50
318
1.69
2.71
6.4
6.7
11.66
11.66
kpa
0.00
45
306
85
616
1.54
2.71
1.6
1.6
18.82
20.19
nmol/l
0.43
71
510
26
134
2.03
2.70
1.2
1.2
—
—
—
0
0
36
211
1.81
2.58
7.5
7.5
—
—
—
0
0
76
552
1.51
2.37
7.1
6.8
—
—
—
0
0
129
1044
1.43
2.30
2.2
2.0
90.16
91.66
pmol/l
0.12
64
534
8
23
3.55
2.28
1.6
1.5
—
—
—
0
0
99
767
1.44
2.22
5.0
4.1
7.41
7.40
ph
0.27
12
138
96
742
1.44
2.17
3.8
4.2
—
—
—
0
0
17
84
2.09
2.00
2.8
3.9
—
—
—
0
0
146
1236
1.37
1.88
10.9
16.7
1.31
1.31
inr
0.03
41
344
24
138
1.81
1.86
5.8
6.3
25.73
24.62
mmol/l
0.85
24
138
5
12
4.22
1.83
4.2
18.0
—
—
—
0
0
29
181
1.67
1.71
4.2
3.2
119.06
82.79
ng/l
0.79
24
159
10
40
2.55
1.68
1.2
1.1
—
—
—
0
0
67
510
1.41
1.61
4.5
3.1
2.48
2.46
mmol/l
0.78
58
447
8
32
2.54
1.61
2.4
3.4
—
—
—
0
0
35
234
1.56
1.59
3.9
3.4
2.53
2.06
mmol/l
0.44
30
188
197
1774
1.36
1.58
8.1
7.7
82.34
79.45
u/l
0.29
182
1654
11
52
2.16
1.46
2.1
2.4
—
—
—
0
0
48
350
1.45
1.46
2.5
2.2
2.24
2.27
g/l
0.09
43
319
100
827
1.32
1.42
4.6
3.2
2.35
2.35
mmol/l
0.09
89
720
78
622
1.35
1.41
2.6
2.0
2.73
3.27
mg/l
1.26
68
533
0
37
0.00
1.35
0.0
1.5
—
—
—
0
0
9
44
2.08
1.28
2.8
3.8
—
—
—
0
0
142
1244
1.28
1.28
7.1
6.4
10.74
11.76
umol/l
0.71
134
1176
113
962
1.29
1.27
5.1
5.7
0.65
0.62
%
0.25
106
892
38
273
1.45
1.26
1.2
1.3
—
—
—
0
0
28
189
1.53
1.24
4.7
4.3
—
—
—
0
0
118
1013
1.28
1.24
5.9
5.9
25.92
26.00
%
0.02
110
939
11
56
2.00
1.23
1.3
1.8
—
—
—
0
0
8
37
2.19
1.22
1.3
1.4
—
—
—
0
0
115
990
1.27
1.17
5.9
5.6
3.10
2.78
%
0.60
108
918
5
20
2.53
1.15
1.0
1.0
—
—
—
0
0
102
868
1.27
1.13
5.1
4.1
827.18
103.73
e6/l
0.55
72
640
115
995
1.26
1.11
7.0
6.0
8.60
8.76
%
0.22
107
925
53
415
1.34
1.08
1.3
1.2
17.08
0.96
u/ml
—
9
112
46
588
0.74
1.07
3.1
3.3
—
—
—
0
0
144
1595
0.80
1.05
3.8
3.8
15.50
15.10
pmol/l
1.09
132
1391
72
593
1.29
1.03
1.5
1.6
1.26
1.29
mmol/l
0.11
66
489
174
1589
1.24
1.01
5.0
4.7
—
—
—
0
0
24
165
1.50
1.00
1.3
1.4
—
—
—
0
0
53
420
1.32
1.00
4.2
3.2
3.44
1.92
e6/l
0.34
32
238
65
531
1.29
0.99
1.9
1.7
1181.59
1171.05
nmol/l
0.03
52
400
10
172
0.57
0.97
1.7
1.6
—
—
—
0
0
48
380
1.32
0.92
1.5
1.5
2.62
2.66
g/l
0.04
24
210
46
362
1.32
0.92
2.2
1.9
—
—
—
0
0
6
28
2.17
0.92
1.3
1.1
—
—
—
0
0
6
28
2.17
0.92
1.2
1.3
—
—
—
0
0
12
193
0.61
0.91
2.9
4.3
1.57
0.93
%
—
7
80
114
1004
1.23
0.91
5.8
5.6
58.27
58.52
%
0.07
105
935
6
29
2.09
0.90
1.0
1.4
1.08
0.54
nmol/l
—
6
24
16
103
1.59
0.89
2.4
2.0
394.14
327.20
ug/l
0.14
16
97
84
717
1.24
0.89
2.7
2.3
57.80
64.47
u/l
0.43
76
667
100
870
1.23
0.89
3.0
2.5
132.55
143.64
ug/l
0.21
94
779
154
1400
1.22
0.89
5.8
4.9
7.08
6.86
mmol/l
0.54
144
1314
43
337
1.32
0.89
2.8
2.2
20.84
21.74
%
0.20
36
289
11
179
0.60
0.88
2.8
4.4
0.00
0.14
%
—
6
66
8
44
1.84
0.86
2.1
2.1
—
—
—
0
0
10
57
1.78
0.84
1.2
1.1
555.30
496.29
mg/l
—
10
52
64
759
0.80
0.84
3.9
4.3
—
—
—
0
0
6
32
1.89
0.82
2.8
3.2
58.83
60.44
%
—
6
32
94
825
1.21
0.76
3.8
3.5
—
—
—
0
0
87
758
1.21
0.76
2.3
2.6
—
—
—
0
0
11
171
0.63
0.74
3.1
4.4
0.00
0.17
%
—
6
58
89
779
1.21
0.74
4.7
3.5
67.83
145.13
e6/l
0.40
70
603
5
25
2.02
0.73
1.0
1.4
—
—
—
0
0
7
39
1.81
0.73
1.1
1.2
—
—
—
0
0
9
57
1.60
0.72
5.0
6.6
—
—
—
0
0
188
1992
0.84
0.71
3.8
4.3
1.27
1.24
mmol/l
0.30
169
1764
17
118
1.47
0.71
3.1
2.9
—
—
—
0
0
225
2147
1.22
0.69
20.4
17.1
29.46
26.14
mg/l
0.77
191
1755
5
27
1.87
0.68
1.0
1.4
—
—
—
0
0
5
28
1.80
0.66
1.8
1.4
—
—
—
0
0
77
673
1.20
0.65
4.1
3.3
—
—
—
0
0
5
29
1.74
0.64
1.2
1.1
152.00
388.50
u/ml
—
5
12
109
985
1.17
0.62
5.8
6.3
—
—
—
0
0
8
50
1.62
0.62
3.0
4.7
5.30
5.06
kpa
—
8
50
8
50
1.62
0.62
3.0
4.7
8.89
7.89
kpa
—
8
50
5
30
1.68
0.61
3.0
2.4
3.80
5.34
e9/l
—
5
30
118
1075
1.17
0.61
2.3
2.7
—
—
—
0
0
12
80
1.52
0.60
5.6
3.2
0.16
0.19
g/l
—
5
28
14
97
1.47
0.60
3.1
3.4
25.45
25.35
mmol/l
0.06
14
92
5
89
0.55
0.57
12.8
10.1
—
—
—
0
0
97
876
1.16
0.55
2.1
2.2
—
—
—
0
0
12
170
0.69
0.55
2.9
4.3
0.86
0.52
%
—
7
62
9
60
1.52
0.55
3.4
3.0
0.91
0.93
nmol/l
—
9
49
116
1063
1.15
0.54
5.7
5.5
0.58
0.60
e9/l
0.39
92
918
32
260
1.26
0.54
2.3
1.7
—
—
—
0
0
120
1103
1.15
0.54
6.0
5.7
0.19
0.19
e9/l
0.05
97
963
9
62
1.47
0.53
1.2
1.2
—
4.42
—
0
6
30
243
1.26
0.52
6.0
4.0
—
—
—
0
0
21
162
1.32
0.51
1.5
1.4
—
—
—
0
0
26
208
1.27
0.50
2.7
1.9
372.19
362.12
nmol/l
0.09
26
192
116
1069
1.14
0.50
5.7
5.5
0.04
0.04
e9/l
0.19
92
924
174
1648
1.14
0.49
4.1
4.4
16.49
14.14
mm/h
1.13
167
1495
10
143
0.69
0.49
2.1
4.6
—
—
—
0
0
191
1994
0.87
0.47
4.7
4.6
1.75
2.04
mu/l
2.49
170
1747
23
183
1.28
0.46
1.4
1.4
—
—
—
0
0
21
165
1.29
0.46
3.3
3.2
—
—
—
0
0
134
1256
1.13
0.43
9.4
9.2
4.28
4.23
e9/l
0.06
110
1098
61
543
1.16
0.42
3.3
2.7
4.76
4.37
e6/l
0.15
56
489
5
32
1.57
0.42
1.2
1.1
—
—
—
0
0
54
609
0.86
0.42
2.8
3.0
8405.62
7113.85
umol/l
0.06
45
506
82
746
1.14
0.42
4.0
3.1
6.38
7.07
mmol/l
0.92
71
607
5
33
1.52
0.41
1.8
1.2
4.18
9.55
u/l
—
5
26
207
2142
0.88
0.41
4.9
5.1
6.16
6.14
mmol/l
0.09
185
1910
8
59
1.37
0.41
1.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.6
—
7.21
—
0
11
0
16
0.00
0.41
0.0
3.4
—
23.18
—
0
5
37
317
1.19
0.40
2.4
2.8
1.63
1.78
%
0.60
30
282
7
101
0.69
0.40
1.3
2.4
4.36
4.30
pmol/l
—
7
89
0
18
0.00
0.40
0.0
2.1
—
8.88
—
0
18
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
190
1823
1.13
0.40
24.7
20.5
15.03
15.48
%
0.60
185
1792
8
61
1.32
0.40
3.1
4.2
7.43
7.41
ph
—
8
53
8
115
0.69
0.37
1.1
1.3
—
—
—
0
0
199
2059
0.89
0.37
4.3
4.8
1.45
1.47
mmol/l
0.24
181
1833
6
41
1.47
0.36
3.5
2.8
16.33
33.65
u/ml
—
6
41
78
715
1.13
0.36
4.2
3.4
0.32
0.57
e6/l
0.73
61
540
6
43
1.40
0.35
1.0
1.9
46.83
59.71
%
—
6
43
116
1089
1.11
0.35
5.7
5.5
1.66
1.89
e9/l
1.10
96
971
92
853
1.12
0.35
3.0
4.0
—
5.89
—
0
38
10
73
1.38
0.35
1.6
1.6
—
—
—
0
0
103
962
1.11
0.34
9.4
10.3
0.00
0.00
e9/l
0.59
73
797
59
533
1.13
0.34
1.9
1.8
444.52
433.87
pmol/l
0.11
48
438
27
230
1.19
0.32
3.0
2.9
67.56
68.78
e9/l
0.04
17
182
202
2080
0.90
0.31
4.4
4.8
4.44
4.47
mmol/l
0.19
185
1865
165
1586
1.10
0.30
3.9
4.3
—
—
—
0
0
48
531
0.88
0.29
2.6
3.2
0.96
0.81
ug/l
0.64
34
386
59
539
1.12
0.29
1.3
1.3
—
—
—
0
0
8
63
1.28
0.28
3.8
1.7
—
—
—
0
0
22
187
1.19
0.27
4.2
3.0
—
—
—
0
0
15
122
1.24
0.27
3.5
2.9
—
—
—
0
0
24
277
0.85
0.26
1.8
1.4
—
—
—
0
0
5
72
0.69
0.26
1.0
1.2
—
—
—
0
0
56
609
0.90
0.26
4.5
4.4
0.00
0.00
estimate
-0.00
17
201
128
1222
1.09
0.26
3.3
3.3
52.77
54.68
u/l
0.09
114
1116
57
524
1.11
0.25
3.6
3.9
—
—
—
0
0
210
2150
0.91
0.25
5.0
5.5
2.61
2.58
mmol/l
0.14
190
1915
23
265
0.86
0.25
1.8
1.3
—
—
—
0
0
35
313
1.13
0.24
1.3
1.2
—
—
—
0
0
23
199
1.17
0.24
1.6
1.4
—
—
—
0
0
7
95
0.73
0.22
1.1
1.2
54.59
200.06
u/ml
—
7
85
5
40
1.25
0.22
3.2
2.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
8.40
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
189.00
—
0
12
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
6
50
1.20
0.20
1.0
1.3
—
—
—
0
0
52
484
1.09
0.19
1.5
1.7
1.10
1.48
mg/l
0.86
43
382
80
759
1.07
0.19
2.6
2.1
509.71
235.89
u/l
0.40
72
709
11
132
0.83
0.18
2.2
2.6
—
—
—
0
0
88
922
0.93
0.18
4.7
5.2
5.16
2.95
ug/l
0.33
76
811
114
1097
1.07
0.18
3.5
4.2
0.00
0.00
estimate
-0.00
20
228
5
67
0.74
0.17
1.0
1.2
—
—
—
0
0
114
1099
1.06
0.17
4.6
5.7
0.00
0.00
estimate
-0.00
18
211
20
225
0.88
0.17
2.7
2.0
262.07
149.58
ug/g
0.48
15
182
8
69
1.16
0.16
1.3
1.5
186.50
273.59
ug/g
—
8
41
19
214
0.88
0.16
2.9
3.5
—
—
—
0
0
233
2298
1.08
0.15
23.6
20.0
139.01
139.63
mmol/l
2.16
226
2233
11
129
0.85
0.15
1.5
2.4
1.25
1.09
%
0.35
11
129
7
89
0.78
0.14
1.0
1.1
—
—
—
0
0
56
591
0.93
0.14
3.3
4.1
—
—
—
0
0
233
2301
1.07
0.13
24.1
20.0
3.95
4.01
mmol/l
1.75
226
2235
224
2212
1.06
0.12
16.9
16.1
—
—
—
0
0
10
116
0.86
0.12
1.6
1.3
—
54.94
—
0
9
17
188
0.90
0.11
1.4
1.5
—
—
—
0
0
11
125
0.88
0.10
1.5
2.4
0.61
0.66
%
0.16
11
125
236
2337
1.06
0.10
28.0
24.8
91.26
91.76
fl
0.80
228
2297
236
2337
1.06
0.10
27.6
24.9
255.78
240.27
e9/l
2.57
223
2270
236
2337
1.06
0.10
28.0
24.9
7.08
6.91
e9/l
0.45
224
2255
236
2337
1.06
0.10
27.9
24.8
30.14
30.44
pg
1.48
228
2297
30
319
0.93
0.09
1.1
1.3
13.78
50.07
iu/ml
—
9
106
236
2338
1.05
0.09
28.1
24.9
4.33
4.40
e12/l
1.32
223
2256
236
2338
1.05
0.09
28.4
25.0
38.37
39.53
%
1.61
206
2166
236
2338
1.05
0.09
28.1
25.0
129.59
133.15
g/l
2.83
228
2294
14
127
1.11
0.08
1.1
1.3
—
—
—
0
0
230
2281
1.04
0.07
24.0
20.4
71.93
81.77
umol/l
3.33
230
2281
9
87
1.04
0.07
1.8
2.0
—
—
—
0
0
9
101
0.89
0.06
1.3
1.3
—
—
—
0
0
113
1111
1.03
0.06
3.5
4.3
0.00
0.00
estimate
-0.00
19
200
23
218
1.06
0.05
1.7
1.3
—
—
—
0
0
205
2065
0.97
0.04
6.2
6.5
40.42
41.00
mmol/mol
0.36
184
1889
50
487
1.03
0.04
4.3
4.7
1.02
1.02
kg/l
0.40
12
75
55
537
1.03
0.04
3.0
3.3
541.84
550.00
mosm/kgh2o
0.13
49
459
100
1013
0.98
0.03
3.3
4.3
71.71
46.50
ng/l
0.38
76
802
80
789
1.02
0.02
4.8
3.7
21.18
9.24
mg/mmol
0.56
51
492
75
742
1.01
0.01
4.2
3.2
106.67
141.22
mg/l
0.14
53
484
228
2273
1.02
0.01
11.7
11.4
26.93
24.27
u/l
1.06
219
2172
10
98
1.02
0.00
2.2
4.6
—
—
—
0
0
12
122
0.98
0.00
1.6
1.3
—
—
—
0
0
18
183
0.98
0.00
4.6
4.0
—
—
—
0
0
24
244
0.98
0.00
1.3
1.3
253.33
526.32
titre
—
6
57
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
3.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
3.80
—
0
8
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
32041.00
—
0
5
0
5
0.00
0.00
0.0
3.2
—
0.64
—
0
5
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
1.06
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
20.80
—
0
5
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
1.63
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.8
—
52.83
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
6
65
0.92
-0.00
2.2
3.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
6.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_SEQULAE_POLIO and mortality.

Females

Parameter HR [95% CI] p-value
AB1_SEQULAE_POLIO 1.391 [1.15, 1.68] < 0.001
Birth year 0.995 [0.99, 1.0] 0.261

During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 652 females with AB1_SEQULAE_POLIO died.

Males

Parameter HR [95% CI] p-value
AB1_SEQULAE_POLIO 1.694 [1.4, 2.05] < 0.001
Birth year 0.988 [0.98, 1.0] 0.01

During the follow-up period (1.1.1998 — 31.12.2019), 273 out of 623 males with AB1_SEQULAE_POLIO died.

Mortality risk

Mortality risk for people of age

years, who have AB1_SEQULAE_POLIO.

N-year risk Females Males
1 0.116% 0.295%
5 0.895% 1.986%
10 2.244% 4.869%
15 4.346% 9.197%
20 7.669% 15.654%

Relationships between endpoints

Index endpoint: AB1_SEQULAE_POLIO – Sequelae of poliomyelitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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