No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
279 |
4. Check minimum number of eventsNone |
279 |
5. Include endpointsNone |
279 |
6. Filter based on genotype QC (FinnGen only) |
279 |
Control definitions (FinnGen only)
- Control exclude
- AB1_SEQULEAE_OF_INFECTIONS_AND_PARASITES
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to Sequelae of poliomyelitis based on the number of shared cases.
Similar with more cases:
- Sequelae of infectious and parasitic diseases
- Certain infectious and parasitic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥Summary Statistics
↥-FinRegistry-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | |||
Whole population | 3267 | 1689 | 1520 |
Only index persons | 2365 | 1316 | 1049 |
Unadjusted period prevalence (%) | |||
Whole population | 0.05 | 0.05 | 0.04 |
Only index persons | 0.04 | 0.05 | 0.04 |
Median age at first event (years) | |||
Whole population | 58.93 | 58.69 | 59.11 |
Only index persons | 57.84 | 57.31 | 58.50 |
-FinnGen-
Key figures
All | Female | Male | |
---|---|---|---|
Number of individuals | 279 | 130 | 149 |
Unadjusted period prevalence (%) | 0.06 | 0.04 | 0.07 |
Median age at first event (years) | 59.05 | 57.03 | 60.81 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 252
- Matched controls
- 2518
LabWAS
↥Mortality – FinRegistry
↥Association
Association between endpoint AB1_SEQULAE_POLIO and mortality.
Females
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_SEQULAE_POLIO | 1.391 [1.15, 1.68] | < 0.001 |
Birth year | 0.995 [0.99, 1.0] | 0.261 |
During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 652 females with AB1_SEQULAE_POLIO died.
Males
Parameter | HR [95% CI] | p-value |
---|---|---|
AB1_SEQULAE_POLIO | 1.694 [1.4, 2.05] | < 0.001 |
Birth year | 0.988 [0.98, 1.0] | 0.01 |
During the follow-up period (1.1.1998 — 31.12.2019), 273 out of 623 males with AB1_SEQULAE_POLIO died.
Mortality risk
Mortality risk for people of age
years, who have AB1_SEQULAE_POLIO.N-year risk | Females | Males |
---|---|---|
1 | 0.116% | 0.295% |
5 | 0.895% | 1.986% |
10 | 2.244% | 4.869% |
15 | 4.346% | 9.197% |
20 | 7.669% | 15.654% |
Relationships between endpoints
↥Index endpoint: AB1_SEQULAE_POLIO – Sequelae of poliomyelitis
GWS hits: -