Traumatic cerebral oedema

ST19_TRAUMAT_CEREBRAL_OEDEMA

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — S06.1 Cause of death: ICD-10 — S06.1 2 out of 7 registries used, show all original rules.	124
4. Check minimum number of events None	124
5. Include endpoints None	124
6. Filter based on genotype QC (FinnGen only)	122

Control definitions (FinnGen only)

Control exclude: NEURODIS

Extra metadata

Level in the ICD hierarchy: 4
Special: ST19_TRAUMCOEDMA
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: S06
Name in latin: Oedema cerebri/encephali traumaticum

NAME	ST19_TRAUMAT_CEREBRAL_OEDEMA
CONTROL_EXCLUDE	NEURODIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	S061
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	S061
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Traumatic cerebral oedema based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	122	48	74
Unadjusted period prevalence (%)	0.03	0.02	0.03
Median age at first event (years)	49.27	46.28	51.20

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
124: Matched controls
1240

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

S06.1

ICD-10 Finland

Traumatic cerebral oedema

+∞

179.0

124

S06.0

ICD-10 Finland

Concussion

87.0

41.8

AA1AD

NOMESCO Finland

CT of head and brain

11.7

40.9

S06.5

ICD-10 Finland

Traumatic subdural haemorrhage

+∞

36.2

T90.5

ICD-10 Finland

Sequelae of intracranial injury

+∞

30.5

S06.2

ICD-10 Finland

Diffuse brain injury

+∞

27.1

W19

ICD-10 Finland

Unspecified fall

7.6

18.3

S06.3

ICD-10 Finland

Focal brain injury

+∞

18.2

111

Kela drug reimbursment

Epilepsy and comparable convulsive disorders

+∞

18.2

R51.80

ICD-10 Finland

Headache

5.7

13.4

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

4.1

13.4

213

N03AX14

ATC

levetiracetam; systemic

144.0

12.7

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

4.8

12.2

I63.9

ICD-10 Finland

Cerebral infarction, unspecified

+∞

11.6

I69.3

ICD-10 Finland

Sequelae of cerebral infarction

+∞

11.6

V49.9

ICD-10 Finland

Car occupant [any] injured in unspecified traffic accident

13.8

10.8

G47.3

ICD-10 Finland

Sleep apnoea

11.1

10.7

X59

ICD-10 Finland

Exposure to unspecified factor

4.2

10.7

106

G40.29

ICD-10 Finland

Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

+∞

10.6

G45.9

ICD-10 Finland

Transient cerebral ischaemic attack, unspecified

32.9

9.6

N03AF02

ATC

oxcarbazepine; oral

32.9

9.6

G40.9

ICD-10 Finland

Epilepsy, unspecified

107.9

9.6

S06.6

ICD-10 Finland

Traumatic subarachnoid haemorrhage

+∞

9.5

AAF00

NOMESCO Finland

Ventriculostomy

+∞

9.5

182

Kela drug reimbursment

Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide

+∞

9.5

ZXD05

NOMESCO Finland

Urgent procedure

3.3

9.0

213

XA800

NOMESCO Finland

Neuropsychological investigation

29.9

8.6

S02.11

ICD-10 Finland

Fracture of base of skull, open

+∞

8.4

AAA27

NOMESCO Finland

Insertion of intracerebral pressure monitoring device

+∞

8.4

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

9.2

8.4

F10.1

ICD-10 Finland

Mental and behavioural disorders due to use of alcohol, Harmful use

7.9

8.1

N06AB04

ATC

citalopram; systemic

3.7

8.0

G44.2

ICD-10 Finland

Tension-type headache

8.0

7.8

F32.9

ICD-10 Finland

Depressive episode, unspecified

4.2

7.6

S42.0

ICD-10 Finland

Fracture of clavicle

10.4

7.5

S02.10

ICD-10 Finland

Fracture of base of skull, closed

+∞

7.4

S06.9

ICD-10 Finland

Intracranial injury, unspecified

+∞

7.4

R56.8

ICD-10 Finland

Other and unspecified convulsions

9.7

7.3

WX105

NOMESCO Finland

Surface analgesia on skin or mucosa

4.6

7.1

TPH07

NOMESCO Finland

Cathetrisation of artery

4.6

7.1

JN5BD

NOMESCO Finland

Head and body CT examination for trauma

14.9

7.0

N03AX12

ATC

[U] gabapentin; oral

3.9

6.6

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

73.5

6.5

L28

ICPC

Limited function/disability (L)

3.6

6.5

N05AH04

ATC

quetiapine; oral

3.5

6.4

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

3.5

6.3

W00

ICD-10 Finland

Fall on same level involving ice and snow

4.1

6.3

A06AD11

ATC

lactulose; oral

3.9

6.3

AAD10

NOMESCO Finland

Evacuation of chronic subdural haematoma

+∞

6.3

S06.4

ICD-10 Finland

Epidural haemorrhage

+∞

6.3

G40.22

ICD-10 Finland

Complex partial epileptic seizure with secondary generalization

+∞

6.3

N06AX11

ATC

mirtazapine; oral

2.7

6.0

197

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

134

3.12

6.76

5.1

2.9

8.92

291.71

ng/l

1.13

107

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

6.18

6.59

13.9

8.2

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

365

2.32

5.02

8.2

5.6

1.20

1.21

mmol/l

0.35

312

(3003396) Base excess in Arterial blood by calculation

3.17

4.84

12.6

6.3

1.45

0.27

mmol/l

0.47

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

12.25

4.33

1.6

1.3

480.71

390.00

mg/l

—

(3044290) Cell count panel - Cerebral spinal fluid

10.42

3.53

2.0

1.7

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.60

3.34

4.5

5.9

23.58

24.38

mmol/l

0.29

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.58

3.28

1.8

1.5

—

(3023368) Bacteria identified in Blood by Culture

195

2.11

3.20

5.3

4.0

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

123

2.29

3.08

1.9

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.49

3.06

2.0

1.5

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

603

1.92

2.98

4.3

3.4

14.48

14.67

pmol/l

0.30

530

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

5.63

2.91

2.1

108.36

435.00

ug/l

—

(3022217) INR in Platelet poor plasma by Coagulation assay

362

1.87

2.87

9.1

14.4

1.31

1.37

inr

0.17

(3021901) Oxygen saturation in Capillary blood

5.67

2.57

1.5

3.5

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.68

2.45

3.6

2.1

86.92

227.59

ng/l

1.74

(3019060) Gas panel - Arterial blood

2.78

2.44

17.0

2.9

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

772

1.90

2.41

5.0

3.8

1.96

1.91

mu/l

0.17

685

(3023419) Bacteria identified in Sputum by Culture

6.45

2.39

2.8

3.4

—

(3012544) pH of Venous blood

2.33

2.38

3.1

3.2

—

(3002582) Erythrocytes [#/volume] in Urine

262

1.78

2.20

3.7

2.9

20.85

25.40

e6/l

0.21

193

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.84

2.18

1.3

1.1

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

4.44

2.18

1.7

1.3

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

105

2.08

2.10

1.9

1.6

1.42

1.43

0.02

(40768797) Stomach Pathology biopsy report

2.09

1.97

1.2

—

(1616796) Gas panel - Central venous blood

4.69

1.96

5.0

4.3

—

(3021589) Normoblasts [#/volume] in Blood

414

1.64

1.94

7.2

7.6

0.00

e9/l

-0.00

342

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.26

1.90

1.9

1.6

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

135

1.86

1.78

3.7

2.5

9.38

2.39

e6/l

0.92

(3022313) Gas panel - Capillary blood

2.90

1.67

1.1

3.4

—

(3030467) Casts [#/volume] in Urine by Automated count

237

1.66

1.67

3.8

2.9

0.14

0.29

e6/l

0.81

173

(3026782) Osmolality of Urine

179

1.73

1.64

2.2

2.7

510.74

563.64

mosm/kgh2o

0.57

153

(3037467) Urinalysis macro (dipstick) panel - Urine

564

1.55

1.60

4.7

3.6

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.02

1.57

2.3

1.8

—

(1002224) Polysomnography panel

2.95

1.52

1.0

—

(3000991) Gas panel - Venous blood

2.03

1.51

5.7

6.9

—

(3011288) Drugs identified in Urine by Screen method

2.41

1.46

1.6

2.7

—

(3010421) pH of Blood

3.21

1.45

4.8

3.8

7.42

—

(3013290) Carbon dioxide [Partial pressure] in Blood

3.21

1.45

4.8

3.8

5.44

4.88

kpa

—

(3027315) Oxygen [Partial pressure] in Blood

3.21

1.45

4.8

3.8

8.40

8.29

kpa

—

(3012501) Base excess in Blood by calculation

3.21

1.45

4.8

3.8

2.10

1.94

mmol/l

—

(3018418) pH of Serum or Plasma

211

1.63

1.44

5.0

3.8

7.39

7.40

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

169

1.68

1.44

1.7

1.6

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

137

1.74

1.41

3.6

2.5

4.12

0.92

e6/l

0.44

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

309

1.54

1.41

3.3

2.9

—

(40760892) CBC W Ordered Manual Differential panel - Blood

403

1.50

1.37

8.0

5.6

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.87

1.30

1.7

1.3

—

(3026008) Bacteria identified in Urine by Culture

234

1.56

1.29

3.6

2.4

—

(3000764) Benzodiazepines [Presence] in Urine

2.00

1.28

1.5

1.9

—

(3018095) Leukocytes [#/volume] in Urine

298

1.51

1.25

4.3

3.2

39.34

77.64

e6/l

0.46

199

(3027944) Amphetamines [Presence] in Urine

1.97

1.23

1.5

1.9

—

(3044889) 12 lead EKG panel

597

1.44

1.18

3.8

3.5

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

658

1.45

1.17

7.8

6.7

82.41

79.60

u/l

0.21

599

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

2.44

1.10

2.6

1.9

0.32

0.30

u/ml

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.94

1.03

1.6

2.2

—

(36304419) Bacteria [Presence] in Urine

228

1.48

1.02

3.9

2.9

—

(3019832) Treponema pallidum Ab [Presence] in Serum

125

1.61

1.01

1.8

1.6

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.99

0.0

1.6

—

33.07

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

118

1.61

0.97

1.6

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

387

1.39

0.97

3.1

2.4

—

(3027008) Opiates [Presence] in Urine

1.79

0.89

1.5

1.9

—

(3045414) Leukocytes [Presence] in Urine

2.05

0.88

1.2

1.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

244

1.42

0.88

3.5

2.8

—

(3028300) Cannabinoids [Presence] in Urine

1.76

0.85

1.5

1.9

—

(3042936) Bacteria identified in Isolate by Culture

106

1.58

0.84

2.0

—

(3016879) Cocaine [Presence] in Urine

1.79

0.82

1.6

2.0

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.71

0.80

1.4

1.5

0.86

1.07

g/l

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.80

0.0

2.0

—

1.09

—

(21494755) Public health laboratory ask at order entry panel

132

0.58

0.79

1.0

1.3

—

(36660697) Celiac disease serology panel - Serum

1.75

0.77

1.1

1.2

—

(3034770) Mitochondria Ab [Titer] in Serum

2.04

0.73

1.4

—

(3003191) Choriogonadotropin (pregnancy test) [Presence] in Serum or Plasma

2.04

0.73

1.6

2.1

—

(3022621) pH of Urine by Test strip

1.62

0.73

1.1

2.2

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.70

0.71

1.6

1.3

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

190

1.40

0.70

1.3

1.2

0.93

0.80

u/ml

—

(3028707) Methadone [Presence] in Urine by Screen method

1.89

0.69

1.0

2.9

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

867

1.35

0.69

4.0

3.8

5.91

5.81

mmol/l

0.24

776

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

100

931

1.38

0.69

20.0

10.7

23.73

25.09

mg/l

0.14

682

(40761536) Microorganisms panel - Urine sediment

1.63

0.68

2.9

3.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

219

1.36

0.66

2.3

1.9

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

104

1.50

0.66

4.6

5.0

105.93

103.92

mmol/l

0.38

104

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

104

0.56

0.65

7.0

7.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

183

0.68

0.61

3.7

2.9

—

(3003694) ABO and Rh group [Type] in Blood

271

0.73

0.61

1.9

1.5

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.60

0.0

2.0

—

0.21

—

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.60

0.0

3.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.53

0.59

4.6

3.0

—

(3000492) Spirometry study

0.56

0.58

1.0

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.54

0.58

1.2

1.6

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

813

1.28

0.57

5.0

4.8

39.24

38.68

mmol/mol

0.21

747

(40768804) Tissue Pathology biopsy report

329

0.77

0.53

2.9

2.3

—

(3029937) Albumin [Presence] in Urine by Test strip

219

1.30

0.51

3.2

3.3

0.00

estimate

-0.00

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.55

0.49

7.1

8.3

0.99

1.17

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.52

0.48

7.1

8.1

84.51

95.25

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.52

0.48

6.9

8.1

0.59

0.67

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

120

0.64

0.48

1.0

1.4

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.45

0.47

1.7

1.2

—

(3025941) Bacteria identified in Stool by Culture

1.49

0.44

1.0

1.4

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.64

0.43

1.4

1.0

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.41

0.42

1.5

2.7

12.50

10.08

g/l

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.41

0.0

3.9

—

58.93

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.3

—

0.00

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

282

1.23

0.41

5.2

3.2

18.32

58.16

ng/l

1.93

179

(3002256) Pathology report gross observation

105

0.65

0.41

1.3

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.41

0.0

1.4

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.45

0.40

2.2

1.9

1.32

1.17

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

1.45

0.40

2.2

1.9

0.60

0.75

—

(40761511) CBC panel - Blood by Automated count

103

986

1.26

0.39

17.0

10.1

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.40

0.38

1.2

2.2

—

(3007164) IgA [Mass/volume] in Serum or Plasma

172

1.27

0.37

1.5

1.3

2.92

2.48

g/l

0.27

114

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.42

0.35

1.7

1.4

—

(3048689) Calprotectin [Mass/mass] in Stool

100

1.34

0.35

1.9

2.8

359.38

201.40

ug/g

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

875

1.20

0.34

15.8

10.3

89.50

85.24

ml/min/173m2

0.91

710

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

193

1.24

0.34

2.3

2.2

—

(3022145) Colonoscopy Study observation

102

1.31

0.31

1.5

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

407

1.17

0.31

6.3

4.1

0.00

estimate

-0.00

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

615

1.16

0.30

4.0

3.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

149

1.24

0.30

3.3

2.2

—

(4035726) Immunohistochemistry procedure

0.68

0.27

1.2

1.5

—

(3013512) EKG study

219

1.18

0.24

4.2

3.6

—

(3012516) Albumin [Mass/volume] in Urine

200

1.18

0.24

3.0

2.9

29.55

85.15

mg/l

1.28

127

(3035350) Ketones [Presence] in Urine by Test strip

414

1.14

0.24

4.7

3.0

0.00

estimate

-0.00

(3015736) pH of Urine

336

1.14

0.23

4.4

2.8

—

6.08

—

(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma

1.29

0.23

1.2

2.8

9.40

6346.68

u/ml

—

(3049717) Cytology report of Urine Cyto stain

1.26

0.22

1.2

2.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

101

0.78

0.22

2.1

2.0

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

104

0.75

0.22

2.0

1.5

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

505

1.12

0.22

10.2

8.9

4.17

4.08

e9/l

0.12

437

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.21

0.0

1.3

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.21

0.0

1.2

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

4.86

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(4200892) Spirometry reversibility

1.26

0.20

1.5

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.24

0.20

1.0

1.2

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.20

0.0

1.2

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.20

0.0

3.9

—

4.96

—

(40768793) Breast Pathology biopsy report

0.00

0.20

0.0

1.6

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.20

0.0

1.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.20

0.0

3.4

—

65.43

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.20

0.0

1.1

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

330

1.13

0.20

5.1

3.1

—

(40758558) Short blood count panel - Blood

214

1.15

0.19

6.7

7.0

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.22

0.18

2.0

2.7

8.70

8.68

ug/l

—

(3009261) Glucose [Presence] in Urine by Test strip

422

1.10

0.16

3.7

3.0

0.00

estimate

-0.00

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.12

0.16

1.8

1.5

—

(3019150) Specific gravity of Urine by Refractometry

199

1.13

0.14

5.8

3.0

1.01

1.02

kg/l

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

103

1010

1.12

0.13

10.2

8.3

27.83

26.95

u/l

0.14

964

(3044640) Blood type and Crossmatch panel - Blood

260

1.10

0.12

3.0

2.1

—

(1761868) Lipid panel - Serum or Plasma

330

1.08

0.11

3.1

2.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

213

1.10

0.10

3.5

3.4

4.69

15.70

mg/mmol

1.15

126

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.81

0.08

1.0

1.4

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

137

1.11

0.08

2.4

2.9

2.44

mmol/l

—

117

(3009542) Hematocrit [Volume Fraction] of Blood

106

1073

0.92

0.07

27.8

16.1

40.18

40.63

0.25

1015

(3000494) Fungus identified in Specimen by Culture

0.84

0.07

1.3

1.4

—

(3003338) MCHC [Mass/volume]

835

0.95

0.06

27.1

13.6

332.90

333.65

g/l

0.27

826

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

131

1.08

0.04

3.6

2.0

—

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

892

1.03

0.02

4.0

3.7

1.40

1.42

mmol/l

0.09

813

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

278

1.01

0.00

5.8

4.1

17.40

21.85

0.71

124

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

922

0.99

0.00

4.3

4.1

2.71

2.73

mmol/l

0.06

844

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

902

0.99

0.00

4.1

3.7

4.62

4.59

mmol/l

0.09

827

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

872

0.99

0.00

3.6

3.3

1.35

1.27

mmol/l

0.39

792

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

289

1.00

0.00

2.4

1.8

82.14

87.27

pmol/l

0.29

160

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

177

1.02

0.00

1.5

—

(3000330) Specific gravity of Urine by Test strip

1.00

0.00

3.8

2.8

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.6

—

100.40

—

(3015183) Erythrocyte sedimentation rate

0.00

-0.00

0.0

1.1

—

(3017704) Immunofixation for Urine

0.00

-0.00

0.0

3.3

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.8

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

2.8

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3019225) pH of Specimen

0.88

-0.00

2.0

5.0

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

0.94

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

2.8

—

392.80

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

-0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3004451) EKG impression Narrative

0.00

-0.00

0.0

1.4

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.4

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

1.8

—

4.04

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3003329) Lymphocytes/100 leukocytes in Synovial fluid

0.00

-0.00

0.0

1.0

—

10.40

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

182.29

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

3.5

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(3036603) Volume of Urine

0.00

-0.00

0.0

2.2

—

2179.17

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

10.0

—

(40766048) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum by Immunoassay

0.00

-0.00

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.2

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

5.77

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

3.4

—

31.80

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.3

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

1.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.1

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.0

—

497.67

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

-0.00

0.0

1.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.90

-0.00

1.6

1.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

120

1.00

-0.00

1.4

1.2

34.78

34.93

iu/ml

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.4

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

1.54

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

4.9

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

1.9

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.98

-0.00

1.4

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.2

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

-0.00

0.0

1.4

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.1

—

(3041067) Sjogrens syndrome-A extractable nuclear 52kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.5

—

(3036432) Mycobacterium tuberculosis genotype [Identifier] in Isolate

0.00

-0.00

0.0

6.2

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

1.8

—

106.89

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_CEREBRAL_OEDEMA – Traumatic cerebral oedema

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R13

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Traumatic cerebral oedema

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Traumatic cerebral oedema (ST19_TRAUMAT_CEREBRAL_OEDEMA)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints