Traumatic cerebral oedema

ST19_TRAUMAT_CEREBRAL_OEDEMA

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — S06.1 Cause of death: ICD-10 — S06.1 2 out of 7 registries used, show all original rules.	120
4. Check minimum number of events None	120
5. Include endpoints None	120
6. Filter based on genotype QC (FinnGen only)	120

Control definitions (FinnGen only)

Control exclude: NEURODIS

Extra metadata

Level in the ICD hierarchy: 4
Special: ST19_TRAUMCOEDMA
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: S06
Name in latin: Oedema cerebri/encephali traumaticum

NAME	ST19_TRAUMAT_CEREBRAL_OEDEMA
CONTROL_EXCLUDE	NEURODIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	S061
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	S061
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Traumatic cerebral oedema based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	120	46	74
Unadjusted period prevalence (%)	0.03	0.02	0.03
Median age at first event (years)	49.31	46.28	51.20

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
108: Matched controls
1080

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

S06.1

ICD-10 Finland

Traumatic cerebral oedema

+∞

155.8

108

S06.0

ICD-10 Finland

Concussion

52.2

32.4

S06.5

ICD-10 Finland

Traumatic subdural haemorrhage

+∞

29.5

AA1AD

NOMESCO Finland

CT of head and brain

15.2

26.3

T90.5

ICD-10 Finland

Sequelae of intracranial injury

160.7

24.8

S06.2

ICD-10 Finland

Diffuse brain injury

+∞

22.7

111

Kela drug reimbursment

Epilepsy and comparable convulsive disorders

+∞

16.0

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

6.0

14.7

132

S06.3

ICD-10 Finland

Focal brain injury

+∞

13.8

W19

ICD-10 Finland

Unspecified fall

9.8

12.2

G40.29

ICD-10 Finland

Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures

+∞

10.6

R51.80

ICD-10 Finland

Headache

7.2

10.2

S42.0

ICD-10 Finland

Fracture of clavicle

24.3

9.6

N03AX14

ATC

levetiracetam; systemic

+∞

9.5

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

5.7

9.4

N03AF02

ATC

oxcarbazepine; oral

40.4

9.2

G47.3

ICD-10 Finland

Sleep apnoea

14.4

8.7

G40.9

ICD-10 Finland

Epilepsy, unspecified

+∞

8.4

AAF00

NOMESCO Finland

Ventriculostomy

+∞

8.4

JN5BD

NOMESCO Finland

Head and body CT examination for trauma

36.4

8.2

I69.3

ICD-10 Finland

Sequelae of cerebral infarction

48.6

7.8

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

11.3

7.8

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

5.6

7.6

G45.9

ICD-10 Finland

Transient cerebral ischaemic attack, unspecified

85.7

7.5

F10.1

ICD-10 Finland

Mental and behavioural disorders due to use of alcohol, Harmful use

7.5

182

Kela drug reimbursment

Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide

+∞

7.4

AAA27

NOMESCO Finland

Insertion of intracerebral pressure monitoring device

+∞

7.4

S02.11

ICD-10 Finland

Fracture of base of skull, open

+∞

7.4

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

+∞

7.4

X59

ICD-10 Finland

Exposure to unspecified factor

4.0

7.3

G44.2

ICD-10 Finland

Tension-type headache

8.0

7.3

V49.9

ICD-10 Finland

Car occupant [any] injured in unspecified traffic accident

9.9

7.3

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

9.9

7.3

XA800

NOMESCO Finland

Neuropsychological investigation

32.4

7.3

N03AX12

ATC

gabapentin; oral

6.2

7.2

R56.8

ICD-10 Finland

Other and unspecified convulsions

10.4

7.0

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

11.1

6.7

I63.9

ICD-10 Finland

Cerebral infarction, unspecified

74.0

6.5

S02.10

ICD-10 Finland

Fracture of base of skull, closed

74.0

6.5

N80

ICPC

Head injury other

74.0

6.5

N06AB04

ATC

citalopram; systemic

3.8

6.5

S06.4

ICD-10 Finland

Epidural haemorrhage

+∞

6.3

AAD10

NOMESCO Finland

Evacuation of chronic subdural haematoma

+∞

6.3

S06.6

ICD-10 Finland

Traumatic subarachnoid haemorrhage

+∞

6.3

G40.22

ICD-10 Finland

Complex partial epileptic seizure with secondary generalization

+∞

6.3

W17

ICD-10 Finland

Other fall from one level to another

11.0

6.2

N05BA04

ATC

oxazepam; oral

3.6

6.1

100

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

6.00

8.46

13.9

8.7

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

139

2.78

5.27

5.2

3.0

9.0

281.2

ng/l

1.14

112

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

14.74

4.63

1.7

1.2

4.5

3.4

mmol/l

—

(3019473) Protein [Mass/volume] in Cerebral spinal fluid

12.28

4.33

1.6

1.3

480.7

320.7

mg/l

—

(3003396) Base excess in Arterial blood by calculation

2.95

3.95

13.1

6.6

1.3

0.3

mmol/l

0.33

(3044290) Cell count panel - Cerebral spinal fluid

12.53

3.80

2.0

1.8

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

366

2.06

3.67

8.4

5.5

1.2

mmol/l

0.14

314

(3023368) Bacteria identified in Blood by Culture

190

2.10

3.09

5.3

3.8

—

(3032080) INR in Blood by Coagulation assay

306

1.95

3.03

6.4

7.2

1.3

inr

0.17

(3023419) Bacteria identified in Sputum by Culture

7.39

2.57

2.8

2.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.37

2.56

1.9

1.5

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.00

2.55

5.2

5.9

23.1

24.5

mmol/l

0.47

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

4.57

2.51

1.3

1.1

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

121

2.11

2.41

1.9

1.7

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

591

1.78

2.35

4.4

3.4

14.6

14.7

pmol/l

0.02

520

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.26

2.31

2.1

1.6

—

(3012544) pH of Venous blood

2.31

2.20

3.2

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

4.45

2.18

1.7

1.3

—

(3019060) Gas panel - Arterial blood

2.72

2.16

17.4

3.1

—

(3021901) Oxygen saturation in Capillary blood

4.69

1.96

1.6

3.5

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

2.45

1.95

3.7

3.1

92.7

221.8

ng/l

1.51

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

758

1.75

1.88

5.0

3.9

2.0

1.9

mu/l

0.29

671

(40768797) Stomach Pathology biopsy report

2.05

1.87

1.2

—

(3002582) Erythrocytes [#/volume] in Urine

266

1.69

1.84

3.5

2.9

21.3

26.1

e6/l

0.22

195

(3022313) Gas panel - Capillary blood

2.91

1.67

1.1

3.6

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.19

1.67

1.8

1.7

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

3.68

1.63

2.4

2.1

105.0

434.5

ug/l

—

(3002032) Base excess in Venous blood by calculation

2.10

1.61

3.4

3.2

0.6

1.2

mmol/l

—

(42870588) Differential panel, method unspecified - Blood

275

1.62

1.60

5.2

4.9

—

(3000991) Gas panel - Venous blood

2.02

1.39

6.1

7.3

—

(3030467) Casts [#/volume] in Urine by Automated count

240

1.58

1.37

3.6

3.0

0.1

0.3

e6/l

0.56

174

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.95

1.36

2.2

1.8

—

(3026782) Osmolality of Urine

173

1.64

1.32

2.0

2.5

523.6

572.4

mosm/kgh2o

0.45

147

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

140

1.70

1.32

3.5

2.6

10.0

2.2

e6/l

1.00

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

166

1.64

1.28

1.6

—

(3037467) Urinalysis macro (dipstick) panel - Urine

565

1.47

1.25

4.7

3.6

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

2.70

1.23

2.6

1.7

0.3

u/ml

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

310

1.49

1.20

3.2

2.9

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

1.18

0.0

1.6

—

34.1

—

(3000850) Epithelial cells [#/volume] in Urine

170

1.59

1.17

2.5

2.6

5.6

3.6

e6/l

0.29

152

(3021589) Normoblasts [#/volume] in Blood

415

1.45

1.15

7.4

0.0

e9/l

0.50

341

(3011288) Drugs identified in Urine by Screen method

2.07

1.14

1.6

2.9

—

(3018418) pH of Serum or Plasma

215

1.53

1.12

5.1

3.8

7.4

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.01

1.09

1.6

1.3

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

647

1.42

1.05

7.7

6.4

82.5

77.6

u/l

0.41

588

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

142

1.58

1.01

3.4

2.5

4.4

0.7

e6/l

0.48

(3018095) Leukocytes [#/volume] in Urine

303

1.43

0.98

4.1

3.2

40.5

77.7

e6/l

0.45

202

(3000764) Benzodiazepines [Presence] in Urine

1.85

0.98

1.5

2.0

—

(36660697) Celiac disease serology panel - Serum

1.83

0.97

1.1

—

(3003694) ABO and Rh group [Type] in Blood

271

0.64

0.95

1.8

1.5

—

(3006504) Eosinophils/100 leukocytes in Blood

399

1.39

0.94

7.9

4.9

2.7

2.8

0.26

372

(3027944) Amphetamines [Presence] in Urine

1.82

0.93

1.5

2.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

242

1.44

0.92

3.5

2.8

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

182

1.47

0.87

1.3

1.2

0.9

0.8

u/ml

—

(3042936) Bacteria identified in Isolate by Culture

105

1.60

0.87

2.0

1.8

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.79

0.84

1.4

1.5

0.9

1.1

g/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

123

1.55

0.83

1.7

1.6

—

(21494755) Public health laboratory ask at order entry panel

125

0.53

0.83

1.0

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

1.75

0.82

1.6

2.3

—

(3026008) Bacteria identified in Urine by Culture

230

1.41

0.80

3.6

2.4

—

(36304419) Bacteria [Presence] in Urine

231

1.40

0.78

3.6

2.9

—

(3044889) 12 lead EKG panel

595

1.33

0.78

3.8

3.5

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

117

1.53

0.77

1.4

1.5

—

(3002256) Pathology report gross observation

106

0.54

0.77

1.3

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.61

0.75

1.8

1.3

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

180

0.63

0.75

3.3

2.8

—

(3016879) Cocaine [Presence] in Urine

1.63

0.73

1.7

2.1

—

(40768804) Tissue Pathology biopsy report

322

0.72

2.7

2.3

—

(3034770) Mitochondria Ab [Titer] in Serum

1.96

0.71

1.4

1.3

—

(1002224) Polysomnography panel

1.89

0.69

1.0

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.67

0.68

7.1

8.5

1.0

1.2

—

(40761536) Microorganisms panel - Urine sediment

1.63

0.68

2.9

3.4

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

1.82

0.67

1.4

1.0

—

(3014007) Fractional oxyhemoglobin in Arterial blood

1.63

0.66

7.1

8.3

84.5

95.1

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.63

0.66

6.9

8.3

0.6

0.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

101

0.57

0.65

7.0

6.5

—

(3027008) Opiates [Presence] in Urine

1.64

0.64

1.6

2.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.56

0.62

4.6

2.7

—

(3045414) Leukocytes [Presence] in Urine

1.69

0.62

1.2

1.7

—

(3025941) Bacteria identified in Stool by Culture

1.61

0.62

1.0

1.4

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

213

1.35

0.61

2.1

2.0

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.61

0.0

2.1

—

0.2

—

(3028300) Cannabinoids [Presence] in Urine

1.61

0.60

1.6

2.0

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.60

0.0

2.1

—

1.1

—

(3029937) Albumin [Presence] in Urine by Test strip

214

1.34

0.59

3.2

3.3

0.0

estimate

0.00

(3026493) Urate [Moles/volume] in Serum or Plasma

196

1.35

0.59

4.4

2.4

342.6

6310.1

umol/l

1.01

169

(3052851) Hemolysis interference index of Serum or Plasma

0.00

0.59

0.0

3.1

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.56

0.54

6.0

5.9

1.6

1.5

mmol/l

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

247

1.29

0.51

1.7

3.2

2.3

2.4

mmol/l

0.32

209

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

391

1.24

0.49

5.2

3.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.55

0.49

1.7

1.2

—

(3000492) Spirometry study

0.59

0.47

1.0

1.4

—

(3007164) IgA [Mass/volume] in Serum or Plasma

167

1.31

0.46

1.5

1.3

2.9

2.5

g/l

0.29

113

(3048689) Calprotectin [Mass/mass] in Stool

1.40

0.43

1.9

2.5

359.4

187.2

ug/g

—

(3022621) pH of Urine by Test strip

1.46

0.43

1.1

2.1

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.64

0.43

2.2

1.9

1.3

1.1

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

912

1.26

0.42

19.8

10.6

24.3

24.7

mg/l

0.04

677

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.3

—

0.0

—

(3028286) Albumin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.3

—

37.7

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.41

0.0

1.4

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

1.3

—

0.0

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.40

0.0

1.5

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.39

0.0

1.2

—

8.8

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

114

0.68

0.39

1.0

1.4

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

1.41

0.38

1.2

2.1

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

855

1.21

0.35

4.0

3.8

5.9

5.8

mmol/l

0.18

768

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.38

0.35

1.7

1.4

—

(3009542) Hematocrit [Volume Fraction] of Blood

874

0.84

0.34

21.8

11.1

40.3

40.7

0.18

680

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

0.70

0.32

1.7

2.0

—

(3022145) Colonoscopy Study observation

102

1.31

0.31

1.5

1.3

—

(3015736) pH of Urine

321

1.17

0.29

4.3

2.8

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

800

1.17

0.28

5.0

4.8

39.2

38.6

mmol/mol

0.21

738

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

601

1.14

0.25

3.9

3.2

—

(3003338) MCHC [Mass/volume]

816

0.87

0.24

26.7

13.5

332.9

333.7

g/l

0.30

809

(3021601) Nitrite [Presence] in Urine by Test strip

404

1.14

0.24

6.1

4.2

0.0

estimate

0.00

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

278

1.16

0.23

5.4

3.2

19.1

53.4

ng/l

1.53

174

(3001604) Monocytes [#/volume] in Blood

415

1.13

0.23

7.0

4.9

0.6

e9/l

0.05

358

(40761511) CBC panel - Blood by Automated count

960

1.18

0.23

16.7

9.9

—

(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma

1.26

0.22

1.2

2.6

9.4

6165.4

u/ml

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.21

0.0

1.3

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.21

0.0

3.8

—

5.1

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.5

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.2

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.21

0.0

3.8

—

58.1

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.21

0.0

2.2

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

146

1.19

0.20

3.2

2.3

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.20

0.0

1.1

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.20

0.0

3.6

—

64.9

—

(40768793) Breast Pathology biopsy report

0.00

0.20

0.0

1.6

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.19

0.19

1.0

1.2

—

(3035350) Ketones [Presence] in Urine by Test strip

410

1.12

0.18

4.6

3.0

0.0

estimate

0.00

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.77

0.16

1.3

1.4

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

325

1.11

0.15

5.1

3.1

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

494

1.09

0.14

10.4

8.4

4.2

4.1

e9/l

0.13

430

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

854

0.91

0.14

3.6

3.4

1.3

mmol/l

0.34

776

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.81

0.14

2.0

1.4

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

883

0.91

0.14

4.2

3.7

4.6

mmol/l

0.20

810

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

902

0.91

0.13

4.4

4.1

2.7

mmol/l

0.01

826

(3009261) Glucose [Presence] in Urine by Test strip

417

1.09

0.13

3.6

3.0

0.0

estimate

0.00

(3049717) Cytology report of Urine Cyto stain

1.17

0.10

1.2

2.3

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.06

0.08

2.2

2.5

9.7

8.6

ug/l

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.06

0.08

1.6

—

(3019150) Specific gravity of Urine by Refractometry

196

1.09

0.07

5.7

2.9

1.0

kg/l

—

(3000494) Fungus identified in Specimen by Culture

0.88

0.07

1.3

—

(40758558) Short blood count panel - Blood

207

1.08

0.06

6.7

6.2

—

(3012516) Albumin [Mass/volume] in Urine

198

1.07

0.06

3.0

2.8

32.5

73.5

mg/l

0.84

125

(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma

873

0.95

0.05

4.0

3.7

1.4

mmol/l

0.04

797

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

292

0.95

0.05

2.4

1.8

82.1

89.7

pmol/l

0.46

152

(40760892) CBC W Ordered Manual Differential panel - Blood

189

1.07

0.05

10.3

3.8

—

(3013512) EKG study

220

1.06

0.04

3.7

3.5

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

132

1.07

0.02

2.1

3.0

2.4

mmol/l

—

114

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

202

1.05

0.02

2.4

2.1

—

(3044640) Blood type and Crossmatch panel - Blood

267

0.97

0.01

3.0

2.0

—

(1761868) Lipid panel - Serum or Plasma

327

0.97

0.01

3.1

2.5

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

114

1.06

0.01

1.4

1.2

34.8

34.9

iu/ml

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

169

1.01

0.00

1.5

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

283

0.99

0.00

5.8

4.1

17.4

21.4

0.62

129

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

128

1.02

0.00

3.5

2.1

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

866

1.02

0.00

15.5

10.3

89.2

85.4

ml/min/173m2

0.74

698

(3020682) Albumin/Creatinine [Ratio] in Urine

211

0.99

0.00

3.9

3.6

5.2

13.9

mg/mmol

0.83

126

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

991

0.99

0.00

10.1

8.2

28.0

26.8

u/l

0.19

946

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3015183) Erythrocyte sedimentation rate

0.00

0.0

1.1

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.92

0.00

1.0

1.4

—

(4010399)

1.02

0.00

1.4

—

(3019601) Blood group antibody investigation [Interpretation] in Plasma or RBC

0.00

0.0

1.2

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.9

—

(3045716) Anion gap in Serum or Plasma

0.00

0.0

1.8

—

10.2

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

0.0

1.0

—

577.6

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

0.0

1.2

—

(3035947) Staphylolysin Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

5.0

—

(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma

0.00

0.0

1.9

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

0.0

2.4

—

(3051651) Icteric interference index of Serum or Plasma

0.00

0.0

2.8

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

1.6

—

106.3

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

0.0

1.5

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

1.7

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.9

—

(3005757) Coagulation factor V activity actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.6

—

93.6

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(3000012) Reticulocyte production index

0.00

0.0

3.0

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(44806420)

0.00

0.0

2.0

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

5.9

—

(40768806) Pleura Pathology biopsy report

0.00

0.0

1.3

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

3.0

—

27.5

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

2.2

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.2

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

0.0

3.8

—

(4211845)

0.00

0.0

1.4

—

(3006462) Nitrate [Presence] in Urine

0.00

0.0

1.4

—

(3020876) Protein [Mass/time] in 24 hour Urine

0.00

0.0

2.0

—

(3019225) pH of Specimen

0.90

0.00

2.0

4.7

—

(3025634) Parainfluenza virus 1 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(21493195) Respiratory pathogens DNA and RNA tested for in Respiratory system specimen by NAA with probe detection

0.00

0.0

1.8

—

(46235128) Lupus anticoagulant aPTT and dRVVT screening panel W Reflex

0.00

0.0

1.0

—

(3017704) Immunofixation for Urine

0.00

0.0

4.2

—

(3000108) Respiratory syncytial virus B RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

2.4

—

(3005156) Respiratory syncytial virus A RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

1.6

—

4.1

—

(3003329) Lymphocytes/100 leukocytes in Synovial fluid

0.00

0.0

1.0

—

10.4

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3036535) Thyroglobulin [Mass/volume] in Serum or Plasma

0.00

0.0

10.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

0.0

1.1

—

(3006262) Parainfluenza virus 3 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3012158) Parainfluenza virus 2 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

(3038297) Parainfluenza virus 4 RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.9

—

(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

0.9

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.0

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

1.5

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.1

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: ST19_TRAUMAT_CEREBRAL_OEDEMA – Traumatic cerebral oedema

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Traumatic cerebral oedema

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Traumatic cerebral oedema (ST19_TRAUMAT_CEREBRAL_OEDEMA)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints