This is a non-core endpoint: only basic statistics are computed.
See its core counterpart C3_ADRENAL_GLAND_EXALLC for full statistics.
Malignant neoplasm of adrenal gland
C3_ADRENAL_GLAND
adrenal gland neoplasm: A neoplasm (disease) that involves the adrenal gland.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
135 |
4. Check minimum number of eventsNone |
135 |
5. Include endpointsNone |
135 |
6. Filter based on genotype QC (FinnGen only) |
135 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF9
Similar endpoints
↥List of similar endpoints to
Malignant neoplasm of adrenal gland
based on the number of shared cases.
Similar with more cases:
- Malignant neoplasm of adrenal gland, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm of endocrine gland
- Malignant neoplasm of endocrine gland, excluding all cancers (controls excluding all cancers)
- Malignant neoplasm
- Any event in cancer register
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 135 | 68 | 67 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 56.49 | 51.41 | 61.64 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 126
- Matched controls
- 1259
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
1900.6
90.5
77
*
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
+∞
54.1
48
*
C74.0
ICD-10 Finland
Malignant neoplasm: Cortex of adrenal gland
+∞
54.1
48
*
8700/3-C74.9
ICD-O-3
Pheochromocytoma, NOS, of adrenal gland, NOS
+∞
39.7
36
*
C74.1
ICD-10 Finland
Malignant neoplasm: Medulla of adrenal gland
+∞
39.7
36
*
BCA30
NOMESCO Finland
Unilateral adrenalectomy
+∞
38.5
35
*
E27.5
ICD-10 Finland
Adrenomedullary hyperfunction
+∞
38.5
35
*
C74.9
ICD-10 Finland
Malignant neoplasm: Adrenal gland, unspecified
+∞
37.4
34
*
130
Kela drug reimbursment
Malignant tumour
15.9
29.9
52
53
H02AB09
ATC
hydrocortisone; systemic
33.4
29.2
38
16
TPH07
NOMESCO Finland
Cathetrisation of artery
12.9
25.7
49
59
8370/3-C74.0
ICD-O-3
Adrenal cortical carcinoma of cortex of adrenal gland
+∞
24.8
23
*
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
108.3
24.7
26
*
8700/3-C74.1
ICD-O-3
Pheochromocytoma, NOS, of medulla of adrenal gland
+∞
23.7
22
*
L01XX23
ATC
mitotane; oral
+∞
22.6
21
*
9500/3-C74.1
ICD-O-3
Neuroblastoma, NOS, of medulla of adrenal gland
+∞
14.9
14
*
BC1CD
NOMESCO Finland
Very extensive CT of adrenal glands
84.2
13.9
15
*
WX302
NOMESCO Finland
Thoracal epidural anesthesy
10.9
13.0
25
28
XW000
NOMESCO Finland
Bone marrow biopsy
13.1
12.6
22
20
H02AA02
ATC
fludrocortisone; oral
28.1
11.4
15
6
BC1AD
NOMESCO Finland
CT of adrenal glands
65.7
10.8
12
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.4
10.6
44
138
BC5AQ
NOMESCO Finland
Chromaffine tissue SPECT with low dose CT
+∞
10.6
10
*
JN4BD
NOMESCO Finland
Extensive body CT
5.8
10.5
31
67
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
32.8
9.6
12
*
JN3AD
NOMESCO Finland
Abdominal CT examination
7.4
9.3
22
35
WX408
NOMESCO Finland
General anesthesy, balanced
3.4
9.1
54
225
A04AA02
ATC
granisetron; systemic, transdermal
9.3
8.9
18
22
WX402
NOMESCO Finland
General anaesthesia
3.9
8.8
40
133
A04AA01
ATC
ondansetron; systemic, rectal
7.0
8.6
21
35
B01AB05
ATC
enoxaparin; parenteral
3.2
7.8
50
214
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
84.9
7.5
8
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
+∞
7.4
7
*
8370/3-C74.9
ICD-O-3
Adrenal cortical carcinoma of adrenal gland, NOS
+∞
7.4
7
*
8010/3-C74.9
ICD-O-3
Carcinoma, NOS, of adrenal gland, NOS
+∞
7.4
7
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
7.4
7
*
2533
FHL
Unilateral removal of additional egg
+∞
7.4
7
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
+∞
7.4
7
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.9
7.0
19
37
WF003
NOMESCO Finland
Adjuvant radiotherapy
11.9
6.4
11
10
Z31.5
ICD-10 Finland
Genetic counselling
6.4
6.4
16
28
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
6.3
6
*
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
72
15
101.71
131.21
5.0
1.3
0.6
—
nmol/l
—
18
0
66
15
85.13
117.42
4.7
1.2
—
—
nmol/l
—
0
0
48
12
61.52
82.06
4.4
4.0
6.2
3.1
nmol/l
0.62
48
12
36
7
69.30
32.24
1.3
1.7
—
—
—
0
0
24
12
24.11
31.78
9.6
1.9
27.7
15.3
ug/l
1.26
24
12
94
481
4.14
13.66
6.1
4.2
—
—
—
0
0
95
512
3.89
12.28
17.5
9.2
1.2
1.2
mmol/l
0.78
72
447
29
73
4.79
11.17
7.1
5.0
1.2
1.2
mmol/l
0.29
29
66
15
7
23.87
10.95
2.4
3.1
74.5
52.9
nmol/l
—
15
7
32
100
3.88
9.21
7.0
6.6
1.4
1.3
mmol/l
0.07
27
79
13
18
7.89
9.01
1.8
1.7
—
—
—
0
0
64
320
2.90
8.42
4.3
3.6
0.3
0.3
e6/l
0.22
56
246
33
117
3.41
7.80
1.8
1.8
—
—
—
0
0
30
100
3.57
7.79
4.7
3.2
—
—
—
0
0
71
389
2.74
7.67
4.2
3.6
—
—
—
0
0
33
119
3.35
7.58
2.0
1.9
—
—
—
0
0
13
22
6.43
7.53
1.7
1.4
—
—
—
0
0
40
164
3.04
7.41
2.3
1.9
—
—
—
0
0
24
72
3.84
7.23
1.7
1.4
—
—
—
0
0
52
252
2.73
7.03
4.7
2.6
—
—
—
0
0
16
36
4.91
6.91
1.8
1.9
—
—
—
0
0
16
36
4.91
6.91
1.7
1.9
—
—
—
0
0
16
40
4.40
6.09
3.8
5.4
201.6
167.4
%
0.76
16
40
13
28
5.03
5.87
1.8
1.6
—
—
—
0
0
15
38
4.32
5.61
2.5
3.0
35.2
4028.8
u/ml
—
10
31
95
659
2.49
5.56
28.9
10.2
3.8
4.2
e9/l
0.95
90
582
24
88
3.10
5.28
22.5
8.1
1.1
1.4
mmol/l
1.61
24
83
26
102
2.92
5.08
26.7
12.0
25.1
24.8
mmol/l
0.12
26
102
12
30
4.29
4.54
1.1
1.2
—
—
—
0
0
8
9
9.36
4.34
1.4
1.3
—
—
—
0
0
13
36
3.89
4.32
1.5
1.3
—
—
—
0
0
35
173
2.38
4.30
2.5
2.7
13.3
13.1
umol/l
0.07
35
160
8
10
8.42
4.12
1.1
1.4
—
—
—
0
0
105
814
2.30
4.01
6.3
3.8
14.2
14.8
pmol/l
1.57
97
745
55
337
2.07
3.95
3.0
2.5
53.7
57.9
u/l
0.47
55
311
8
12
7.01
3.73
7.0
4.8
—
—
—
0
0
9
16
5.94
3.72
1.6
1.2
—
—
—
0
0
9
18
5.27
3.43
1.4
1.3
—
—
—
0
0
11
32
3.65
3.41
1.6
2.0
—
—
—
0
0
5
5
10.31
3.00
2.0
1.4
—
—
—
0
0
6
9
6.91
2.90
1.7
1.0
—
—
—
0
0
91
711
1.86
2.84
4.2
3.6
84.3
45.7
u/l
2.76
85
677
14
54
2.78
2.80
1.6
1.7
—
—
—
0
0
5
6
8.59
2.77
3.2
1.5
6.4
4.5
nmol/l
—
5
6
115
989
2.10
2.46
6.0
4.5
1.8
2.0
mu/l
0.98
106
907
9
27
3.50
2.44
1.1
2.4
—
—
—
0
0
6
12
5.18
2.43
1.3
1.7
—
—
—
0
0
34
206
1.87
2.38
3.7
3.1
0.3
0.9
e6/l
2.23
19
133
33
198
1.88
2.38
3.9
3.5
1.3
1.9
e6/l
0.20
19
125
6
13
4.77
2.29
2.3
1.9
—
—
—
0
0
5
9
5.72
2.23
1.8
1.1
—
—
—
0
0
18
89
2.18
2.18
34.3
8.6
24.4
23.6
mmol/l
0.45
18
83
8
26
3.20
2.05
1.4
1.5
—
—
—
0
0
7
22
3.30
1.90
1.0
1.6
—
—
—
0
0
29
179
1.79
1.90
4.9
3.1
71.8
229.3
ng/l
1.25
24
133
93
782
1.61
1.76
5.0
4.3
14.2
11.8
mm/h
0.67
86
721
6
19
3.25
1.68
2.0
1.6
—
—
—
0
0
15
77
2.07
1.67
4.5
4.0
63.4
62.2
ml/min/173m2
—
8
33
7
26
2.78
1.60
1.3
2.8
—
—
—
0
0
7
26
2.78
1.60
1.0
1.5
—
—
—
0
0
7
27
2.68
1.53
1.1
1.5
—
—
—
0
0
7
27
2.68
1.53
1.9
1.6
—
—
—
0
0
7
27
2.68
1.53
1.1
1.5
—
—
—
0
0
107
945
1.64
1.51
31.3
12.4
82.5
82.7
ml/min/173m2
0.03
95
747
7
29
2.49
1.41
1.3
2.1
—
—
—
0
0
5
19
2.69
1.22
1.8
1.6
—
—
—
0
0
19
288
0.60
1.22
1.3
1.5
0.7
2.6
u/ml
—
6
67
5
20
2.56
1.16
1.8
1.6
—
—
—
0
0
7
31
2.32
1.12
2.1
7.0
25.9
24.5
mmol/l
—
7
26
6
125
0.46
1.11
16.8
7.7
—
—
—
0
0
12
68
1.84
1.04
2.0
2.1
—
—
—
0
0
10
54
1.92
0.99
1.8
1.6
—
—
—
0
0
0
31
0.00
0.97
0.0
1.5
—
—
—
0
0
33
248
1.44
0.96
2.8
2.2
1.2
1.3
mg/l
0.03
21
193
36
278
1.40
0.91
3.7
3.9
0.0
0.0
estimate
0.00
22
96
0
25
0.00
0.80
0.0
1.7
—
—
—
0
0
5
25
2.04
0.73
1.0
1.5
—
—
—
0
0
9
58
1.59
0.71
2.2
1.8
—
—
—
0
0
61
530
1.28
0.67
4.1
4.1
0.0
0.0
estimate
0.00
22
93
16
112
1.49
0.67
2.1
2.2
—
—
—
0
0
60
521
1.27
0.66
6.0
5.8
0.0
0.0
estimate
0.00
25
96
115
1089
1.38
0.61
33.4
14.0
32.2
23.1
mg/l
2.07
104
860
17
124
1.42
0.59
2.2
2.4
—
—
—
0
0
0
23
0.00
0.59
0.0
1.5
—
—
—
0
0
104
975
1.29
0.56
4.8
4.0
1.5
1.3
mmol/l
1.18
95
899
6
99
0.59
0.54
1.3
1.8
—
—
—
0
0
59
523
1.23
0.52
4.1
4.0
0.0
0.0
estimate
0.00
24
98
44
380
1.23
0.49
2.1
1.9
85.0
93.6
pmol/l
0.60
22
188
46
402
1.22
0.46
3.8
4.1
—
—
—
0
0
45
393
1.22
0.45
4.5
4.1
26.7
46.2
ng/l
1.12
31
267
106
1007
1.25
0.43
42.5
15.3
37.6
39.9
%
2.32
78
779
5
31
1.64
0.43
1.4
1.4
—
—
—
0
0
5
34
1.49
0.41
2.0
1.7
—
—
—
0
0
34
293
1.21
0.39
2.7
3.5
1911.6
1257.4
ng/l
0.39
26
247
6
41
1.48
0.36
2.8
1.9
—
—
—
0
0
22
184
1.23
0.33
2.4
1.6
1293.6
1176.3
nmol/l
0.21
17
140
6
47
1.29
0.32
2.2
1.4
—
—
—
0
0
32
285
1.16
0.26
5.3
4.0
36.7
73.3
mg/mmol
0.26
21
188
106
1025
1.16
0.24
5.1
5.0
2.7
2.8
mmol/l
0.12
97
947
5
37
1.36
0.24
2.2
2.1
—
—
—
0
0
5
38
1.33
0.23
1.4
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
19.1
—
0
11
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
104
1008
1.14
0.21
4.9
4.5
4.7
4.6
mmol/l
0.47
96
938
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
103
1003
1.11
0.16
4.8
4.5
1.5
1.4
mmol/l
0.10
94
927
23
207
1.13
0.16
3.0
2.9
1.3
0.8
ug/l
0.75
14
139
38
360
1.08
0.10
4.4
4.9
4.1
2.0
ug/l
0.59
30
318
6
71
0.84
0.08
1.0
1.4
—
—
—
0
0
72
737
0.95
0.07
3.6
3.3
—
—
—
0
0
9
83
1.09
0.07
3.0
2.9
3.4
6.7
ug/l
—
9
75
27
283
0.94
0.06
3.6
4.6
26.7
20.2
%
0.43
13
140
15
151
0.99
0.00
1.3
1.4
—
—
—
0
0
24
242
0.99
0.00
1.5
1.9
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
0.00
0.0
4.8
—
162.7
—
0
6
0
7
0.00
0.00
0.0
2.0
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
7
0.00
0.00
0.0
2.6
—
126.6
—
0
7
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
0
6
0.00
0.00
0.0
1.0
—
142.5
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
4.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.8
—
522.8
—
0
6
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
3.2
—
129.4
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: C3_ADRENAL_GLAND – Malignant neoplasm of adrenal gland
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).