Malignant neoplasm of adrenal gland, including Hilmo

C3_ADRENAL_GLAND_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C74
  • Hospital discharge: ICD-9 1940
  • Hospital discharge: ICD-8 1940
  • Cause of death: ICD-10 C74
  • Cause of death: ICD-9 1940
  • Cause of death: ICD-8 1940
  • Cancer registry: Topography ICD-O-3 C74
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

3 out of 7 registries used, show all original rules.

265

4. Check minimum number of events

None

265

5. Include endpoints

None

265

6. Filter based on genotype QC (FinnGen only)

252

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 252 131 121
Unadjusted period prevalence (%) 0.05 0.05 0.06
Median age at first event (years) 57.70 54.53 61.13

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
265
Matched controls
2650
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
336.6
143.8
134
8
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
80.5
130.6
71
12
130
Kela drug reimbursment
Malignant tumour
+∞
110.3
98
*
C74.9
ICD-10 Finland
Malignant neoplasm: Adrenal gland, unspecified
+∞
107.9
96
*
C74.0
ICD-10 Finland
Malignant neoplasm: Cortex of adrenal gland
+∞
104.2
93
*
BCA31
NOMESCO Finland
Endoscopic unilateral adrenalectomy
459.0
96.7
91
*
C74.1
ICD-10 Finland
Malignant neoplasm: Medulla of adrenal gland
+∞
91.0
82
*
H02AB09
ATC
hydrocortisone; systemic
25.8
87.1
65
33
H02AB02
ATC
dexamethasone; systemic
45.0
74.0
45
12
E27.5
ICD-10 Finland
Adrenomedullary hyperfunction
+∞
71.1
65
*
BCA30
NOMESCO Finland
Unilateral adrenalectomy
+∞
64.2
59
*
TPH07
NOMESCO Finland
Cathetrisation of artery
8.9
55.4
85
134
JN4BD
NOMESCO Finland
Extensive body CT
14.5
53.1
52
44
A04AA01
ATC
ondansetron; systemic, rectal
16.2
49.7
45
33
WX302
NOMESCO Finland
Thoracal epidural anesthesy
18.9
47.0
39
24
JN4AD
NOMESCO Finland
Body CT examination
13.0
43.6
45
41
8700/3-C74.9
ICD-O-3
Pheochromocytoma, NOS, of adrenal gland, NOS
+∞
41.8
39
*
A03FA01
ATC
metoclopramide; systemic, rectal
6.0
36.7
82
185
8370/3-C74.0
ICD-O-3
Adrenal cortical carcinoma of cortex of adrenal gland
+∞
35.2
33
*
L01XX23
ATC
mitotane; oral
+∞
35.2
33
*
XW000
NOMESCO Finland
Bone marrow biopsy
15.0
34.6
32
24
A04AA02
ATC
granisetron; systemic, transdermal
365.7
32.6
32
*
Z51.5
ICD-10 Finland
Palliative care
13.9
32.1
31
25
8700/3-C74.1
ICD-O-3
Pheochromocytoma, NOS, of medulla of adrenal gland
+∞
31.9
30
*
WX402
NOMESCO Finland
General anaesthesia
4.2
23.8
82
256
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
23.3
22
*
H02AA02
ATC
fludrocortisone; oral
42.7
22.2
27
7
ZXE20
NOMESCO Finland
More than three and less than five hours
4.6
21.9
62
166
ZXE10
NOMESCO Finland
More than one and less than three hours
3.4
20.9
127
569
JN3AD
NOMESCO Finland
Abdominal CT examination
5.1
20.9
49
112
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
20.0
19
*
XX3DW
NOMESCO Finland
Time consuming IT work
7.6
20.0
30
44
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
113.6
19.9
21
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
6.4
19.5
35
62
N02AA05
ATC
oxycodone; systemic
4.3
19.5
60
170
L03AA02
ATC
filgrastim; parenteral
+∞
19.0
18
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
19.0
18
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.3
17.7
92
369
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
13.9
17.6
30
24
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
17.2
143
747
9500/3-C74.1
ICD-O-3
Neuroblastoma, NOS, of medulla of adrenal gland
+∞
16.8
16
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.4
16.4
46
121
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.6
16.3
66
225
Z31.5
ICD-10 Finland
Genetic counselling
6.0
16.1
30
55
ZX120
NOMESCO Finland
Intravenous
5.1
15.4
35
77
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.2
15.0
73
278
WZC00
NOMESCO Finland
Treatment plan or consultation
2.9
15.0
104
484
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
84.9
14.7
16
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
14.7
14
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
14.7
14
*
BC5AQ
NOMESCO Finland
Chromaffine tissue SPECT with low dose CT
+∞
14.7
14
*
BC1CD
NOMESCO Finland
Very extensive CT of adrenal glands
45.1
14.3
17
*
B01AB05
ATC
enoxaparin; parenteral
2.9
14.2
93
418
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
18.9
14.1
21
12
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
79.3
13.7
15
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
22.6
13.5
19
9
WZC30
NOMESCO Finland
Teaching
3.5
13.4
52
171
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.4
12.8
52
176
L01BC06
ATC
capecitabine; oral
+∞
12.6
12
*
B01AB10
ATC
tinzaparin; parenteral
4.3
12.0
33
85
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
11.9
11.8
21
19
L03AA13
ATC
pegfilgrastim; parenteral
68.0
11.7
13
*
BC5AN
NOMESCO Finland
Chromaffine and adrenergic tissue isotope imaging (MIBG)
+∞
11.5
11
*
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
11.5
11
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
11.5
11
*
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
16.0
11.5
18
12
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
14.8
11.1
18
13
WW500
NOMESCO Finland
Blood transfusion
8.9
11.1
23
28
JN4CD
NOMESCO Finland
Very extensive body CT
16.4
11.0
17
11
TPX10
NOMESCO Finland
Implantation of vascular injection port
11.3
11.0
20
19
J01MA12
ATC
levofloxacin; systemic
3.0
11.0
58
229
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
62.6
10.7
12
*
XX9AN
NOMESCO Finland
Complementary isotope examination or additional picture
114.4
10.5
11
*
E24.9
ICD-10 Finland
Cushing syndrome, unspecified
114.4
10.5
11
*
105
Kela drug reimbursment
Adrenal cortical hypofunction
114.4
10.5
11
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
10.5
10
*
D35.59
ICD-10 Finland
Other paragangliom
+∞
10.5
10
*
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
34.0
10.4
13
*
E34.9
ICD-10 Finland
Endocrine disorder, unspecified
41.8
10.0
12
*
BC1AD
NOMESCO Finland
CT of adrenal glands
17.6
10.0
15
9
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.9
10.0
31
87
H03AA01
ATC
levothyroxine sodium; systemic
2.5
9.8
75
356
ZXD10
NOMESCO Finland
Scheduled procedure
2.3
9.8
111
630
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
5.5
9.5
19
37
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.8
9.5
22
49
2533
FHL
Unilateral removal of additional egg
103.6
9.5
10
*
E24.8
ICD-10 Finland
Other Cushing syndrome
103.6
9.5
10
*
I15.2
ICD-10 Finland
Hypertension secondary to endocrine disorders
103.6
9.5
10
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
5.2
9.5
20
41
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
9.4
9
*
A04AD12
ATC
aprepitant; systemic
+∞
9.4
9
*
E27.1
ICD-10 Finland
Primary adrenocortical insufficiency
+∞
9.4
9
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
9.4
9
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
9.4
9
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
9.4
9
*
Z85.8
ICD-10 Finland
Personal history of malignant neoplasms of other organs and systems
+∞
9.4
9
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
9.4
9
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
9.4
9
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.7
9.3
22
50
ZXE00
NOMESCO Finland
One hour or less
2.2
9.2
114
667
N05BA06
ATC
lorazepam; systemic, sublingual
4.5
9.1
23
55
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.6
9.1
32
98
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
4.8
9.0
21
47
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.4
8.7
33
106
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
8.3
8.5
18
23
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
11.3
8.4
15
14
BC1BD
NOMESCO Finland
Extensive CT of adrenal glands
+∞
8.4
8
*
115
Kela drug reimbursment
Breast cancer
+∞
8.4
8
*
1940B
ICD-9 Finland
Malignant neoplasm of other endocrine glands and related structures, Adrenal gland[NEUROBLASTOMA SUPRARENALIS]
+∞
8.4
8
*
KKB10
NOMESCO Finland
Excision of retroperitoneal tumour
+∞
8.4
8
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
8.4
8
*
9101
FHL
Bone biopsy
+∞
8.4
8
*
WF002
NOMESCO Finland
Radical radiotherapy
34.5
8.1
10
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
8.1
31
100
N02AA01
ATC
morphine; systemic, rectal
22.9
8.1
11
5
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
46.4
7.8
9
*
JAH00
NOMESCO Finland
Laparotomy
7.5
7.6
17
24
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.5
7.5
26
79
ZX121
NOMESCO Finland
Central venous catheter
82.3
7.5
8
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
7.4
82
452
N02AX02
ATC
tramadol; systemic, rectal
2.0
7.4
117
738
C74
ICD-10 Finland
Malignant neoplasm of adrenal gland
+∞
7.3
7
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
7.3
7
*
Y77
ICPC
Malignant neoplasm prostate
+∞
7.3
7
*
9109
FHL
Other measure in this category
+∞
7.3
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
7.3
7
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
7.3
7
*
JN7AQ
NOMESCO Finland
Somatostatin receptor SPET med low dose CT
+∞
7.3
7
*
116
Kela drug reimbursment
Prostate cancer
+∞
7.3
7
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
7.3
7
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
7.3
7
*
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
+∞
7.3
7
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
7.3
7
*
8010/3-C74.9
ICD-O-3
Carcinoma, NOS, of adrenal gland, NOS
+∞
7.3
7
*
L01AX03
ATC
temozolomide; systemic
+∞
7.3
7
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
9.7
6.9
13
14
JN1CD
NOMESCO Finland
Very extensive CT examination of upper part of abdomen
41.1
6.8
8
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
41.1
6.8
8
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
6.8
62
315
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.2
6.7
27
90
ZXE30
NOMESCO Finland
More than five and less than seven hours
4.4
6.7
17
41
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
71.5
6.5
7
*
KAC10
NOMESCO Finland
Total nephrectomy with capsule
71.5
6.5
7
*
Z2446
NOMESCO Finland
Social worker
2.9
6.4
31
115
GD1AD
NOMESCO Finland
Thorax CT examination
4.0
6.4
18
47
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
18.6
6.3
9
5
Q85.82
ICD-10 Finland
of Hipple-Lindau syndrome
+∞
6.3
6
*
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
+∞
6.3
6
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
+∞
6.3
6
*
WX1CG
NOMESCO Finland
Extensive total body MRI with high intensity magnet
+∞
6.3
6
*
V04CD01
ATC
metyrapone; oral
+∞
6.3
6
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
6.3
6
*
HAC20
NOMESCO Finland
Total mastectomy
+∞
6.3
6
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
6.3
6
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
6.3
6
*
8370/3-C74.9
ICD-O-3
Adrenal cortical carcinoma of adrenal gland, NOS
+∞
6.3
6
*
R50.9
ICD-10 Finland
Fever, unspecified
2.3
6.2
50
240
A41.9
ICD-10 Finland
Sepsis, unspecified
4.3
6.2
16
39
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
12.9
6.1
10
8

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
113
32
60.82
189.67
4.2
1.3
—
—
—
0
0
100
33
48.06
159.68
4.2
1.2
—
—
nmol/l
—
0
0
100
57
27.57
129.97
1.5
1.5
—
—
—
0
0
69
38
24.20
89.46
3.8
1.6
—
—
—
0
0
37
9
47.40
30.85
7.4
1.3
24.31
13.37
ug/l
—
37
9
61
144
5.20
25.29
1.4
1.1
—
—
—
0
0
125
524
3.62
23.45
6.3
3.1
7.39
7.40
ph
0.82
45
85
27
8
37.35
21.58
1.3
1.4
307.35
59.38
nmol/24h
—
27
8
175
940
3.54
21.50
11.8
3.8
13.92
13.86
umol/l
0.01
170
877
77
248
3.97
21.15
7.6
7.8
1.12
1.12
mmol/l
0.02
72
230
107
434
3.46
20.67
7.8
3.4
—
—
—
0
0
42
87
5.55
19.96
3.3
1.5
4.39
2.29
ug/l
0.72
35
68
38
72
5.99
19.84
6.2
11.7
—
—
—
0
0
168
929
3.21
18.70
14.2
7.0
1.21
1.22
mmol/l
0.74
135
808
124
580
3.14
18.48
2.3
1.6
—
—
—
0
0
153
824
3.03
17.45
3.8
2.3
—
—
—
0
0
92
374
3.24
17.24
3.6
3.1
529.26
559.96
mosm/kgh2o
0.70
80
312
52
152
4.01
16.06
2.4
2.5
0.22
0.20
g/l
0.49
47
140
48
133
4.19
15.94
6.3
3.2
1.22
1.23
mmol/l
0.11
48
114
56
179
3.70
15.18
6.3
8.3
13.82
11.80
kpa
1.47
51
171
56
179
3.70
15.18
6.3
8.3
5.26
5.23
kpa
0.06
51
170
112
542
2.85
15.04
4.0
2.0
—
—
—
0
0
184
1157
2.93
14.77
10.2
4.7
6.49
6.71
mmol/l
0.66
177
1060
88
385
2.92
14.13
3.4
2.5
3.81
4.42
e6/l
0.46
81
343
54
179
3.53
13.79
6.4
8.3
0.62
1.57
mmol/l
0.89
45
144
107
529
2.72
13.51
4.5
3.2
—
—
—
0
0
96
451
2.77
13.37
8.3
3.6
91.71
89.02
%
0.44
96
439
108
548
2.64
12.81
4.6
3.2
0.31
0.32
e6/l
0.04
90
399
113
593
2.58
12.43
4.7
3.3
59.42
166.82
e6/l
0.46
91
443
69
284
2.93
12.19
2.9
2.2
29.86
29.59
s
0.17
69
275
153
943
2.47
11.69
26.0
7.6
0.00
0.00
e9/l
0.66
128
760
107
571
2.47
11.11
6.9
2.0
2.35
2.35
mmol/l
0.14
101
477
21
39
5.76
11.06
2.6
2.0
28.06
16.97
u/ml
0.38
16
32
139
838
2.39
10.92
15.3
14.1
1.16
1.33
inr
1.87
58
252
61
257
2.78
10.18
2.1
2.6
24.63
22.68
%
0.27
53
229
53
209
2.92
9.98
7.4
3.4
11.87
7.25
umol/l
0.27
47
177
168
1131
2.33
9.82
22.7
6.6
4.05
4.16
e9/l
0.24
155
977
147
958
2.20
9.01
14.3
6.1
—
—
—
0
0
116
697
2.18
8.64
5.7
3.9
80.61
93.37
e6/l
0.08
94
475
45
177
2.86
8.46
11.3
9.6
—
—
—
0
0
17
21
8.57
8.22
2.3
1.6
—
—
—
0
0
42
162
2.89
8.17
20.5
12.6
24.72
24.82
mmol/l
0.06
42
162
151
1029
2.09
7.86
13.6
5.5
0.60
0.57
e9/l
0.44
133
887
151
1032
2.08
7.76
13.6
5.5
0.04
0.04
e9/l
0.36
133
892
13
11
12.35
7.66
2.8
1.0
—
—
—
0
0
17
24
7.49
7.61
2.6
3.8
16.52
50.22
mu/l
0.54
17
24
154
1066
2.06
7.58
15.7
5.8
0.19
0.20
e9/l
0.21
138
933
32
112
3.11
7.35
1.3
1.4
—
—
—
0
0
152
1057
2.03
7.27
13.6
5.6
1.87
1.96
e9/l
0.42
136
933
10
5
20.69
7.18
1.9
1.0
40.23
1.95
umol/24h
—
10
5
23
66
3.72
7.17
3.5
2.2
14.03
8.81
u/l
0.65
17
52
84
475
2.13
7.05
16.3
5.3
—
—
—
0
0
49
224
2.46
6.79
6.9
2.9
1.62
1.60
%
0.08
49
206
12
12
10.41
6.60
4.0
4.0
—
—
—
0
0
25
82
3.26
6.38
2.8
2.0
20.30
16.94
iu/l
0.20
20
66
39
165
2.60
6.33
5.1
2.7
63.85
65.17
e9/l
0.07
29
124
87
521
2.00
6.13
1.6
1.5
—
—
—
0
0
10
8
12.93
6.13
1.4
1.8
2124.30
1555.63
ml
—
10
8
12
14
8.92
6.12
4.7
2.6
37.31
39.71
%
0.18
12
14
31
119
2.82
6.06
4.8
4.9
0.69
0.26
%
1.70
13
27
32
126
2.75
5.97
6.8
4.9
0.00
0.07
%
0.79
13
29
31
120
2.79
5.97
7.0
5.0
0.08
0.04
%
0.17
12
23
15
26
6.05
5.93
1.0
1.3
—
—
—
0
0
84
502
1.99
5.93
2.2
2.2
3.02
2.91
mg/l
0.16
73
431
33
133
2.69
5.89
6.7
4.8
1.11
0.72
%
0.56
14
36
17
35
5.12
5.85
3.8
4.8
—
—
—
0
0
19
56
3.58
5.70
4.8
2.8
—
—
—
0
0
44
208
2.34
5.63
1.4
1.5
—
—
—
0
0
9
7
13.25
5.62
1.2
1.3
—
—
—
0
0
37
163
2.48
5.52
4.0
3.4
—
—
—
0
0
174
1338
1.87
5.47
4.2
3.1
73.49
44.44
u/l
1.86
162
1245
15
31
5.06
5.20
2.7
3.3
15.16
17.02
%
—
9
16
59
324
2.06
5.20
4.3
3.1
2.69
2.31
e6/l
0.13
33
175
10
12
8.61
5.10
1.5
1.1
—
—
—
0
0
15
41
3.82
5.00
1.9
1.6
—
—
—
0
0
10
13
7.94
4.89
1.9
3.4
—
—
—
0
0
15
34
4.61
4.83
3.4
3.9
2.22
3.06
mmol/l
—
10
16
15
34
4.61
4.83
3.4
3.9
8.39
8.64
kpa
0.24
15
34
15
34
4.61
4.83
3.4
3.9
4.94
4.80
kpa
0.24
15
34
12
21
5.93
4.81
2.8
1.9
—
—
—
0
0
36
168
2.32
4.73
2.4
2.0
24.79
37.65
u/l
1.28
29
139
10
14
7.37
4.69
5.4
1.8
—
—
—
0
0
37
176
2.28
4.66
6.5
8.6
7.43
7.42
ph
—
7
12
194
1587
1.83
4.53
5.9
3.8
14.67
14.81
pmol/l
0.31
181
1431
46
246
2.05
4.32
2.2
1.9
—
—
—
0
0
13
29
4.66
4.31
1.0
1.0
—
—
—
0
0
26
109
2.54
4.30
4.9
4.9
—
—
—
0
0
61
368
1.85
4.03
4.4
3.7
704.66
224.19
ng/l
0.46
47
272
163
1295
1.67
3.95
5.3
4.1
7.80
381.37
e6/l
—
5
16
10
19
5.43
3.86
5.4
1.8
—
—
—
0
0
185
1527
1.70
3.80
4.6
4.1
15.82
11.16
mm/h
2.97
175
1386
6
5
12.23
3.78
1.0
1.0
—
—
—
0
0
20
79
2.66
3.73
5.8
7.0
0.18
0.38
g/l
0.64
15
36
11
25
4.54
3.66
1.0
1.0
—
—
—
0
0
10
21
4.90
3.59
3.2
1.9
32.60
32.71
pg
—
10
21
7
9
7.95
3.58
2.6
1.3
5.43
3.98
nmol/l
—
7
9
170
1384
1.64
3.57
5.5
4.2
—
—
—
0
0
13
36
3.74
3.55
4.3
5.0
—
—
—
0
0
8
13
6.31
3.52
4.4
1.9
962.88
563.62
e6/l
—
8
13
8
13
6.31
3.52
1.0
1.4
—
—
—
0
0
169
1381
1.62
3.43
4.5
3.6
—
—
—
0
0
7
10
7.15
3.38
2.1
5.3
1.88
1.84
ug/l
—
7
10
49
293
1.82
3.31
1.6
1.6
—
—
—
0
0
9
19
4.86
3.27
1.7
1.9
265.44
283.64
mosm/kgh2o
—
9
11
118
894
1.58
3.25
3.3
2.8
196.59
93.28
ug/l
2.57
113
826
77
527
1.65
3.22
3.7
3.3
—
—
—
0
0
8
15
5.46
3.21
1.3
1.2
—
—
—
0
0
59
380
1.71
3.09
1.8
1.8
—
—
—
0
0
28
142
2.09
3.03
6.1
8.8
—
—
—
0
0
80
564
1.60
2.94
3.0
2.9
—
—
—
0
0
68
462
1.63
2.90
1.6
1.5
18.50
20.87
nmol/l
0.67
63
391
33
182
1.93
2.85
1.4
1.3
—
—
—
0
0
11
33
3.43
2.84
2.7
3.5
53.91
55.67
%
0.12
11
33
5
6
8.46
2.76
1.2
1.5
—
—
—
0
0
90
662
1.54
2.73
3.7
3.6
6.03
7.51
mmol/l
3.28
79
560
6
10
6.11
2.71
1.7
3.3
—
—
—
0
0
12
42
2.94
2.58
3.8
1.7
—
—
—
0
0
13
50
2.68
2.57
1.5
1.9
176.25
249.70
u/ml
—
8
20
9
27
3.41
2.41
2.4
1.1
—
—
—
0
0
10
33
3.11
2.38
2.8
3.0
2.69
4.19
e9/l
—
10
33
37
226
1.74
2.33
21.4
5.4
2.13
1.85
mmol/l
0.26
32
179
16
72
2.30
2.32
1.6
1.8
—
—
—
0
0
8
23
3.55
2.29
1.3
1.5
—
—
—
0
0
5
9
5.64
2.22
1.2
1.1
—
—
—
0
0
38
239
1.69
2.17
1.7
1.5
—
—
—
0
0
9
31
2.97
2.09
2.3
5.8
—
—
—
0
0
41
266
1.64
2.08
1.5
1.2
—
—
—
0
0
5
10
5.07
2.08
1.2
1.1
—
—
—
0
0
5
10
5.07
2.08
1.4
1.8
2014.00
2020.00
ml
—
5
10
6
16
3.81
1.94
1.0
1.6
—
—
—
0
0
56
398
1.52
1.94
1.9
1.7
445.07
440.03
pmol/l
0.05
46
320
213
1935
1.51
1.93
6.0
4.5
1.81
1.95
mu/l
0.88
198
1751
9
34
2.70
1.88
1.8
1.9
4.93
4.50
mmol/24h
—
9
29
5
12
4.22
1.83
1.2
1.1
163.60
148.83
mmol/24h
—
5
12
119
993
1.36
1.68
3.8
3.7
0.00
0.02
estimate
0.50
37
166
6
19
3.21
1.67
7.0
5.6
11.13
9.90
mg/l
—
6
19
6
19
3.21
1.67
2.0
3.0
—
—
—
0
0
117
976
1.36
1.65
5.7
5.2
0.00
0.00
estimate
-0.00
38
167
117
980
1.35
1.59
3.8
3.7
0.00
0.01
estimate
0.50
40
184
203
1854
1.41
1.55
39.0
13.2
14.54
14.68
%
0.18
198
1826
66
506
1.41
1.54
3.6
3.8
0.00
0.00
estimate
-0.00
33
167
5
126
0.39
1.54
1.2
1.4
—
—
—
0
0
5
15
3.38
1.53
2.4
1.1
—
—
—
0
0
5
15
3.38
1.53
79.6
3.0
8.60
12.36
%
—
5
15
7
27
2.63
1.52
1.1
1.4
—
—
—
0
0
40
282
1.49
1.45
1.3
1.4
834.29
474.93
titre
—
7
71
5
123
0.40
1.41
1.0
1.2
—
—
—
0
0
19
112
1.75
1.39
2.1
1.3
—
—
—
0
0
66
516
1.37
1.37
3.3
2.5
332.71
8211.52
umol/l
2.49
59
449
55
417
1.40
1.37
2.5
1.8
1.33
0.92
mg/l
0.99
40
314
213
1976
1.40
1.35
4.5
4.3
5.92
5.92
mmol/l
0.00
204
1791
70
554
1.36
1.35
3.7
3.8
—
—
—
0
0
11
205
0.52
1.34
1.5
1.4
—
—
—
0
0
11
55
2.04
1.29
1.5
1.6
1.01
0.69
nmol/l
0.91
11
46
8
35
2.32
1.28
50.1
3.3
—
—
—
0
0
89
736
1.32
1.27
4.6
3.5
30.74
40.80
ng/l
0.69
63
503
94
786
1.30
1.24
1.8
1.9
82.40
95.85
pmol/l
2.06
44
385
8
37
2.20
1.22
1.1
1.7
—
—
—
0
0
5
21
2.41
1.09
5.8
5.7
6.42
6.14
mmol/l
—
5
15
7
135
0.51
1.01
1.1
1.2
—
15.20
—
0
5
202
1887
1.30
1.01
6.2
5.7
40.00
39.88
mmol/mol
0.07
195
1748
9
52
1.76
0.93
1.1
1.1
—
—
—
0
0
6
29
2.09
0.90
1.5
3.5
—
—
—
0
0
8
43
1.89
0.88
2.0
2.9
9.53
6.36
umol/l
—
8
34
6
30
2.02
0.87
66.5
2.6
51.67
70.71
%
—
6
30
13
80
1.66
0.86
4.2
4.9
—
—
—
0
0
21
146
1.48
0.85
1.3
1.2
62.90
94.21
iu/ml
—
10
59
74
631
1.24
0.80
3.9
3.8
23.82
38.27
mg/mmol
0.20
47
391
10
158
0.62
0.73
2.6
3.0
—
—
—
0
0
219
2096
1.26
0.70
27.1
11.1
31.06
21.81
mg/l
3.17
199
1564
69
597
1.21
0.65
3.1
3.3
144.31
183.17
mg/l
0.12
44
374
44
526
0.80
0.63
1.3
1.5
0.84
2.16
u/ml
1.57
13
136
5
30
1.68
0.61
1.6
2.2
—
—
—
0
0
5
30
1.68
0.61
1.6
2.2
105.00
105.50
mmol/l
—
5
30
5
30
1.68
0.61
1.6
2.2
4.00
4.06
mmol/l
—
5
30
0
20
0.00
0.60
0.0
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.0
—
-3.25
—
0
8
0
22
0.00
0.59
0.0
1.4
—
3.01
—
0
12
0
22
0.00
0.59
0.0
1.3
—
3.66
—
0
12
62
546
1.18
0.49
2.5
1.6
2.01
1.37
mmol/l
0.95
56
466
13
93
1.42
0.49
31.5
3.5
0.68
0.61
%
0.24
13
93
208
2005
1.17
0.47
4.6
4.4
4.80
4.64
mmol/l
1.16
192
1862
22
273
0.79
0.45
2.5
2.3
220.59
106.17
ug/g
0.35
17
218
211
2039
1.17
0.44
5.0
4.9
2.82
2.76
mmol/l
0.36
193
1884
5
31
1.62
0.43
1.2
1.2
—
—
—
0
0
8
56
1.44
0.43
1.5
1.2
—
54.00
—
0
5
8
60
1.34
0.40
2.0
1.7
—
—
—
0
0
0
18
0.00
0.40
0.0
1.2
—
1.67
—
0
10
10
71
1.42
0.40
1.2
1.8
—
—
—
0
0
5
36
1.40
0.38
1.2
1.2
—
—
—
0
0
20
161
1.26
0.38
4.9
3.7
—
—
—
0
0
228
2224
1.18
0.38
19.4
8.4
27.09
26.14
u/l
0.28
221
2120
5
37
1.36
0.37
5.4
1.4
—
—
—
0
0
38
433
0.86
0.35
4.2
3.7
1.02
1.02
kg/l
0.07
11
64
52
466
1.14
0.34
1.4
1.4
3.28
2.41
g/l
0.44
35
250
198
1922
1.12
0.31
4.5
3.9
1.52
1.26
mmol/l
3.38
182
1763
34
386
0.86
0.30
1.4
1.3
46.36
40.77
iu/ml
0.08
15
126
7
55
1.28
0.30
2.7
5.1
—
—
—
0
0
8
108
0.73
0.29
3.4
3.7
—
—
—
0
0
18
149
1.22
0.28
1.4
1.4
—
—
—
0
0
234
2378
0.86
0.27
43.7
16.7
38.47
40.33
%
4.87
222
2203
234
2378
0.86
0.27
42.1
16.6
7.02
6.70
e9/l
1.34
227
2287
234
2378
0.86
0.27
41.9
16.6
4.34
4.54
e12/l
6.99
228
2287
204
1990
1.11
0.26
4.6
4.4
1.44
1.47
mmol/l
0.47
187
1837
31
350
0.87
0.26
1.3
1.3
5.19
14.06
u/ml
—
7
139
5
75
0.66
0.26
1.0
1.2
—
—
—
0
0
234
2376
0.87
0.25
42.2
16.6
267.75
251.48
e9/l
2.31
228
2290
13
105
1.25
0.25
1.5
1.2
—
—
—
0
0
17
201
0.84
0.24
1.1
1.2
—
—
—
0
0
7
92
0.75
0.23
1.0
1.1
—
—
—
0
0
7
94
0.74
0.22
1.0
1.8
—
—
—
0
0
5
40
1.25
0.22
1.0
1.3
60.60
52.80
pmol/l
—
5
40
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
61.0
—
5.82
—
0
10
0
10
0.00
0.21
0.0
7.0
—
0.65
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
39
356
1.11
0.20
2.0
1.7
1319.60
1231.26
nmol/l
0.20
28
273
9
111
0.80
0.20
1.9
2.6
—
—
—
0
0
75
708
1.08
0.20
3.4
2.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
171.50
—
0
14
37
347
1.08
0.12
2.9
2.5
0.94
0.74
ug/l
0.37
24
216
10
86
1.17
0.11
1.1
1.2
—
—
—
0
0
22
238
0.92
0.10
1.3
1.6
—
—
—
0
0
5
46
1.09
0.09
1.8
1.2
—
—
—
0
0
21
227
0.92
0.09
1.5
1.8
—
—
—
0
0
6
56
1.07
0.08
8.0
1.3
—
—
—
0
0
6
58
1.04
0.08
1.2
1.2
32.17
38.98
g/l
—
6
51
45
469
0.95
0.08
3.4
3.6
—
—
—
0
0
23
218
1.06
0.05
2.5
1.7
—
—
—
0
0
20
191
1.05
0.03
1.4
1.4
—
—
—
0
0
63
620
1.02
0.02
4.4
3.6
3.12
1.91
ug/l
0.58
52
551
222
2212
1.02
0.01
24.5
10.6
—
—
—
0
0
12
126
0.95
0.00
1.9
2.6
—
—
—
0
0
22
219
1.00
0.00
1.5
1.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.6
—
8.88
—
0
5
8
86
0.93
-0.00
3.9
1.3
—
—
—
0
0
7
74
0.94
-0.00
6.9
1.4
—
—
—
0
0
8
84
0.95
-0.00
3.7
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.5
—
75.94
—
0
8
8
86
0.93
-0.00
3.9
1.3
—
—
—
0
0
8
87
0.92
-0.00
4.5
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
0.85
—
0
5
0
6
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
8
87
0.92
-0.00
3.7
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
153.20
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
7.2
—
7.82
—
0
6
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
28.15
—
0
6

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_ADRENAL_GLAND_WIDE – Malignant neoplasm of adrenal gland, including Hilmo

GWS hits: 1

This endpoint is excluded (different definition than used in FinnGen).