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ILD medications: nintedanib

ILD_NINTENDANIB

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Medicine purchases: ATC L01XE31

1 out of 7 registries used, show all original rules.

194

4. Check minimum number of events

Min. number of events 3
194

5. Include endpoints

None

194

6. Filter based on genotype QC (FinnGen only)

189

Control definitions (FinnGen only)

Control exclude
ILD_MEDICATIONS

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 189 55 134
Unadjusted period prevalence (%) 0.05 0.02 0.06
Median age at first event (years) 70.52 71.24 70.22

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
194
Matched controls
1940
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L01XE31
ATC
[U] nintedanib
+∞
280.8
194
*
284
Kela drug reimbursment
Nintedanib and pirfenidone
+∞
278.5
194
*
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
+∞
260.7
194
13
356
Kela drug reimbursment
Nintedanib and pirfenidone
8277.5
203.4
159
*
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
154.5
194.7
99
13
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
58.2
163.4
103
37
L01EX09
ATC
nintedanib; oral
2339.0
124.2
107
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
35.1
108.3
76
35
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
45.0
107.2
68
23
L04AX05
ATC
pirfenidone; oral
+∞
99.8
87
*
XG410
NOMESCO Finland
Flow-volume spirometry
34.9
93.4
64
27
UGC12
NOMESCO Finland
Flexible bronchoscopy
18.6
84.8
83
75
TGC00
NOMESCO Finland
Bronchial lavation
30.7
67.5
47
20
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
16.7
59.1
56
46
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
28.5
55.1
39
17
H02AB06
ATC
prednisolone; systemic
9.8
53.0
141
415
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
9.3
48.0
75
123
GD1AD
NOMESCO Finland
Thorax CT examination
11.2
44.8
55
66
GD1AA
NOMESCO Finland
Thorax X-ray examination
11.1
37.9
170
754
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
12.6
36.3
39
38
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
354.6
30.7
30
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
5.4
29.9
95
295
R03AC02
ATC
salbutamol; inhalant
6.0
29.3
146
650
Z51.5
ICD-10 Finland
Palliative care
6.7
28.4
54
105
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
7.8
26.9
42
66
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
65.0
24.8
28
5
N02AA01
ATC
morphine; systemic, rectal
28.1
24.4
33
14
J96.1
ICD-10 Finland
Chronic respiratory failure
29.2
24.0
32
13
R03BA08
ATC
ciclesonide; inhalant
7.8
24.0
37
57
L04AA06
ATC
mycophenolic acid; systemic
+∞
22.3
21
*
R05
ICD-10 Finland
Cough
4.7
22.1
68
199
R06.0
ICD-10 Finland
Dyspnoea
4.2
21.5
91
337
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
123.4
21.0
22
*
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
61.6
19.4
22
*
Z94.2
ICD-10 Finland
Lung transplant status
+∞
19.1
18
*
GDG10
NOMESCO Finland
Bilateral transplantation of lung
+∞
18.0
17
*
R03BB04
ATC
tiotropium bromide; inhalant
5.7
17.9
38
80
127
Kela drug reimbursment
Transplant complication
+∞
16.9
16
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.5
16.5
91
390
WX721
NOMESCO Finland
Oxygen concentrator therapy
+∞
15.8
15
*
R28
ICPC
Limited function/disability (R)
34.8
15.1
19
6
R02
ICPC
Shortness of breath/dyspnoea
4.2
14.2
44
126
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
+∞
13.7
13
*
GX2C5
NOMESCO Finland
Short-lasting oximetry
+∞
12.6
12
*
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.9
12.4
30
70
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
3.8
12.4
44
138
R03AK08
ATC
formoterol and beclometasone; inhalant
13.8
11.9
20
16
J01FA10
ATC
azithromycin; systemic
2.9
11.9
111
613
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.9
11.9
83
393
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
32.3
11.8
15
5
GX1K5
NOMESCO Finland
Diffusion capacity
127.2
11.6
12
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
11.5
62
253
R03BA01
ATC
beclometasone; inhalant
4.3
11.4
33
89
R03AK07
ATC
formoterol and budesonide; inhalant
3.6
11.0
42
138
XG466
NOMESCO Finland
Sleep oxymetry
9.4
10.9
22
26
L04AX01
ATC
azathioprine; systemic
116.0
10.5
11
*
GX1D5
NOMESCO Finland
Flow volume spirometry
116.0
10.5
11
*
L04AD01
ATC
ciclosporin; systemic
+∞
10.5
10
*
N02AA05
ATC
oxycodone; systemic
3.0
10.2
57
236
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.5
10.2
27
68
J47
ICD-10 Finland
Bronchiectasis
21.4
10.0
14
7
A02BC02
ATC
pantoprazole; systemic
3.1
9.8
152
1051
WX726
NOMESCO Finland
High-flow oxygen therapy
104.9
9.5
10
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
9.4
80
410
WX892
NOMESCO Finland
Monitored bed care
4.1
9.4
28
77
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.8
9.4
31
92
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
9.8
9.3
18
20
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
10.8
9.2
17
17
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.9
9.2
29
83
J01MA14
ATC
moxifloxacin; systemic
4.0
8.9
27
75
R01AD12
ATC
fluticasone furoate; nasal
2.7
8.8
60
274
XJC10
NOMESCO Finland
Oesophageal pH monitoring
52.4
8.8
10
*
R05
ICPC
Cough
2.7
8.8
58
261
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
29.0
8.6
11
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
7.1
8.4
20
31
L04AD02
ATC
tacrolimus; systemic
+∞
8.4
8
*
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
+∞
8.4
8
*
J01FA06
ATC
roxithromycin; oral
2.4
8.2
86
480
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
10.7
8.2
15
15
R4110
NOMESCO Finland
Physiotherapy
2.5
8.1
74
387
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
6.6
8.1
20
33
R5140
NOMESCO Finland
Monitoring the use of the aid
3.1
7.9
38
143
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.4
7.8
79
433
J45.9
ICD-10 Finland
Asthma, unspecified
3.2
7.7
33
116
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
7.3
7.5
17
25
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
7.1
101
632
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.7
6.9
41
173
SPAT1262
SPAT
Handing over of treatment supplies
2.5
6.8
53
256
J01CA04
ATC
amoxicillin; systemic
2.6
6.7
157
1200
WW200
NOMESCO Finland
Immunization
12.9
6.7
11
9
R99
ICPC
Respiratory disease other
9.2
6.7
13
15
J01MA12
ATC
levofloxacin; systemic
2.5
6.6
49
230
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.9
6.5
33
127
WX725
NOMESCO Finland
Noninvasive ventilation
3.9
6.5
20
56
AA3AI
NOMESCO Finland
Cone beam CT of facial bones
72.1
6.5
7
*
J84
ICD-10 Finland
Other interstitial pulmonary diseases
+∞
6.3
6
*
R29
ICPC
Respiratory symptom/complaint other
3.9
6.2
19
53
XG474
NOMESCO Finland
Exhalation nntrogen oxide
10.5
6.1
11
11
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
10.5
6.1
11
11
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
10.5
6.1
11
11

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
68
20
51.81
111.70
2.9
1.6
—
—
—
0
0
111
135
17.88
95.20
1.5
1.2
345.81
438.57
titre
0.16
31
28
95
123
14.18
76.24
4.7
4.5
—
—
—
0
0
46
18
33.19
67.99
1.4
1.2
—
—
—
0
0
41
15
34.39
61.73
5.3
1.7
57.24
59.13
%
0.23
41
15
41
15
34.39
61.73
5.0
1.6
4.86
4.26
e9/l
0.38
41
15
100
182
10.28
59.89
1.5
1.2
37.91
24.98
iu/ml
0.40
35
47
181
660
27.00
57.12
17.9
3.8
—
—
—
0
0
41
24
21.39
51.17
3.8
2.6
—
—
—
0
0
100
224
8.15
48.18
11.0
7.6
1.93
1.02
mmol/l
1.71
88
176
70
117
8.80
43.69
2.2
1.3
—
—
—
0
0
71
124
8.45
42.54
3.9
1.4
—
—
—
0
0
48
66
9.33
34.78
1.4
1.3
—
—
—
0
0
43
58
9.24
31.49
1.3
1.1
167.94
118.99
u/ml
0.51
38
52
34
38
10.64
28.59
2.5
2.2
140.70
126.68
g/l
—
10
29
134
573
5.33
27.78
4.0
3.0
961.02
1394.31
ng/l
1.04
120
492
63
145
5.95
27.74
14.5
6.0
8.15
10.52
mmol/l
1.99
63
140
35
17
24.80
24.97
1.1
1.0
2.84
2.71
u/ml
—
25
7
64
164
5.33
24.73
1.2
1.2
6.60
2.52
u/ml
0.53
15
57
118
489
4.61
24.61
5.0
3.9
—
—
—
0
0
66
179
5.07
23.75
3.9
1.3
—
—
—
0
0
48
100
6.05
23.22
4.9
3.5
7.42
7.41
ph
—
6
12
152
791
5.26
22.70
10.8
5.4
1.19
1.20
mmol/l
2.26
147
704
55
134
5.33
22.34
1.5
1.4
—
—
—
0
0
30
39
8.92
22.33
1.3
1.3
—
—
—
0
0
48
105
5.75
21.97
1.5
1.2
—
—
—
0
0
44
89
6.10
21.88
5.2
2.9
0.78
0.25
%
0.65
27
32
30
40
8.69
21.87
11.8
2.6
3.40
2.12
mmol/l
1.58
30
23
49
110
5.62
21.79
1.4
1.4
—
—
—
0
0
46
103
5.54
20.44
5.4
2.9
0.50
0.72
%
0.44
29
39
25
7
40.67
20.39
2.4
2.0
—
—
—
0
0
24
7
38.81
19.41
1.2
1.0
—
—
—
0
0
28
40
8.01
19.20
8.3
2.7
—
—
—
0
0
30
47
7.37
18.98
11.8
2.8
7.43
7.42
ph
0.41
30
39
28
16
20.21
18.90
1.1
1.0
357.74
233.33
u/ml
—
23
9
80
297
3.88
18.37
2.5
1.5
1.54
1.17
mg/l
0.53
70
235
36
71
6.00
18.22
4.8
3.5
—
—
—
0
0
26
39
7.54
17.04
3.2
2.1
16.70
16.11
%
—
9
20
43
106
4.93
16.93
18.9
10.4
—
—
—
0
0
35
75
5.47
16.14
4.6
3.5
—
—
—
0
0
194
1584
+∞
16.02
33.8
13.4
22.39
26.94
mg/l
1.47
188
1229
40
99
4.83
15.61
4.8
2.9
0.05
0.17
%
0.69
22
35
28
26
12.38
15.60
1.1
1.0
—
—
—
0
0
106
513
3.35
15.51
5.3
3.4
7.41
7.40
ph
0.44
33
85
144
849
3.70
15.03
12.0
6.1
1.20
1.20
mmol/l
0.57
120
716
87
383
3.31
14.74
11.1
5.9
—
—
—
0
0
37
93
4.68
14.11
5.2
3.0
0.05
0.07
%
0.08
20
29
99
485
3.13
13.76
4.2
2.9
—
—
—
0
0
121
691
3.00
12.35
21.1
8.0
0.00
0.00
e9/l
1.02
115
551
17
8
23.12
12.24
1.4
1.0
—
—
—
0
0
104
559
2.85
11.70
4.4
3.1
38.70
40.51
e6/l
0.03
86
422
61
245
3.17
11.66
1.9
1.3
3.10
2.75
g/l
0.69
49
132
141
893
3.12
11.61
10.5
14.9
1.27
1.34
inr
0.47
57
245
42
136
3.67
11.27
3.1
3.4
—
—
—
0
0
97
513
2.78
11.10
4.1
3.0
0.44
0.51
e6/l
0.16
81
377
159
1107
3.42
10.55
6.1
3.7
—
—
—
0
0
20
23
9.56
10.06
1.3
1.0
—
—
—
0
0
107
617
2.64
10.01
5.7
3.6
22.47
49.81
e6/l
1.36
86
440
95
519
2.63
9.91
4.0
1.9
108.11
337.80
u/l
1.00
90
488
65
296
2.80
9.70
3.1
1.8
28.31
29.45
s
1.74
65
288
18
20
9.80
9.26
2.4
1.4
87.89
89.59
%
0.35
18
20
48
192
2.99
9.03
4.6
2.3
10.27
12.84
umol/l
0.38
48
174
113
709
2.42
8.29
4.1
3.8
40.48
45.21
ng/l
0.10
96
552
48
202
2.83
8.18
1.1
1.3
—
—
—
0
0
62
305
2.52
7.71
3.9
3.0
0.51
0.94
e6/l
0.72
37
176
70
365
2.44
7.67
4.9
3.6
1292.72
419.75
ng/l
1.02
60
314
194
1768
+∞
7.07
49.1
21.1
41.16
40.31
%
1.05
178
1614
73
407
2.27
6.71
8.0
2.5
8555.26
13578.04
umol/l
0.24
66
336
21
60
3.80
6.65
1.4
1.2
—
—
—
0
0
40
172
2.67
6.45
17.5
7.2
1.55
1.33
mmol/l
0.72
40
167
31
117
2.96
6.36
2.0
1.7
203.23
147.28
ug/g
0.49
26
92
9
5
18.77
6.32
1.1
1.0
—
—
—
0
0
51
251
2.40
6.19
4.3
1.8
—
—
—
0
0
35
144
2.75
6.13
2.0
2.2
76.52
69.59
e9/l
0.33
22
112
11
11
10.52
6.11
1.6
1.5
—
—
—
0
0
71
419
2.10
5.47
1.9
1.3
—
—
—
0
0
168
1371
2.68
5.44
37.2
17.5
15.02
15.41
%
0.45
168
1345
10
11
9.51
5.35
1.0
1.0
—
—
—
0
0
9
8
11.72
5.34
3.3
2.0
—
—
—
0
0
5
0
+∞
5.23
1.6
0.0
9.60
—
%
—
5
0
5
0
+∞
5.23
1.4
0.0
—
—
—
0
0
50
262
2.22
5.18
2.1
2.4
12.57
13.15
umol/l
0.22
50
237
154
1224
2.25
5.05
6.9
4.4
—
—
—
0
0
35
160
2.45
4.93
20.7
8.5
—
—
—
0
0
62
360
2.06
4.91
3.4
3.0
567.81
586.50
mosm/kgh2o
0.31
57
298
109
771
1.94
4.89
4.4
3.4
0.00
0.01
estimate
0.50
37
154
79
504
1.96
4.79
2.7
2.8
—
—
—
0
0
109
778
1.92
4.68
4.5
3.4
0.00
0.00
estimate
-0.00
36
126
85
561
1.92
4.62
5.6
3.5
2.33
2.35
mmol/l
0.64
78
486
108
771
1.90
4.61
6.2
4.6
0.00
0.00
estimate
-0.00
38
138
7
5
14.45
4.61
1.4
2.2
1.04
0.88
e9/l
—
7
5
44
231
2.17
4.49
2.1
2.4
23.85
23.78
%
0.01
36
196
59
349
1.99
4.38
4.4
3.3
—
—
—
0
0
69
437
1.90
4.17
4.2
3.6
0.00
0.00
estimate
-0.00
35
129
60
371
1.89
3.86
2.1
1.8
469.60
19192368.01
pmol/l
0.50
48
297
6
5
12.32
3.79
5.3
1.0
—
—
—
0
0
14
40
3.69
3.69
4.6
2.3
—
—
—
0
0
13
39
3.50
3.29
1.5
1.5
230.63
280.12
ug/g
—
8
24
20
86
2.48
3.20
3.3
3.1
24.72
23.96
mmol/l
0.27
20
86
77
554
1.65
2.80
4.1
4.0
—
—
—
0
0
82
608
1.60
2.60
3.2
3.3
50.96
167.28
mg/l
0.57
60
410
82
614
1.58
2.47
3.2
3.2
7.22
7.74
mmol/l
0.53
66
502
84
647
1.53
2.17
3.8
3.8
6.80
9.61
mg/mmol
0.43
55
419
10
37
2.79
2.10
1.3
1.2
—
—
—
0
0
0
56
0.00
2.10
0.0
4.5
—
—
—
0
0
79
605
1.52
2.07
2.4
2.4
234.16
173.82
ug/l
0.97
74
544
180
1663
2.14
2.06
5.4
5.8
2.60
2.59
mmol/l
0.06
159
1492
11
45
2.53
1.97
3.9
2.7
35.73
35.57
umol/l
0.01
11
40
58
420
1.54
1.95
3.7
3.3
—
—
—
0
0
27
161
1.79
1.91
3.2
3.3
—
—
—
0
0
177
1637
1.93
1.84
5.2
5.2
6.02
6.18
mmol/l
1.33
154
1453
162
1464
1.65
1.81
4.6
4.3
1.96
2.07
mu/l
0.59
143
1267
6
18
3.40
1.76
1.5
1.8
—
—
—
0
0
133
1155
1.48
1.75
3.8
3.5
14.96
15.02
pmol/l
0.10
121
985
5
13
3.92
1.72
1.0
1.0
—
—
—
0
0
173
1608
1.70
1.50
4.8
5.1
1.38
1.39
mmol/l
0.21
150
1433
60
460
1.44
1.50
1.8
1.4
19.81
21.46
nmol/l
0.36
55
379
174
1621
1.71
1.47
4.8
5.1
4.38
4.42
mmol/l
0.18
151
1473
26
167
1.64
1.43
3.8
3.3
2.05
1.64
mmol/l
0.11
21
137
26
167
1.64
1.43
3.8
3.3
5.92
5.62
kpa
0.66
26
162
28
185
1.60
1.39
1.1
1.3
—
—
—
0
0
6
23
2.66
1.38
1.7
1.4
—
—
—
0
0
5
17
2.99
1.36
3.4
3.1
—
—
—
0
0
168
1560
1.57
1.34
4.3
4.5
1.32
1.29
mmol/l
0.27
147
1381
8
34
2.41
1.31
2.1
2.8
—
—
—
0
0
5
18
2.82
1.29
1.0
1.0
—
—
—
0
0
5
18
2.82
1.29
1.0
1.6
9.72
11.05
%
—
5
18
8
36
2.27
1.26
2.0
1.2
—
—
—
0
0
25
165
1.59
1.25
3.0
2.0
12.17
12.78
nmol/l
0.16
25
144
6
26
2.35
1.19
1.0
1.1
—
—
—
0
0
21
135
1.62
1.17
1.3
1.3
—
—
—
0
0
16
96
1.73
1.14
2.1
2.5
—
—
—
0
0
75
623
1.33
1.12
2.4
2.1
—
—
—
0
0
5
21
2.42
1.09
1.2
1.3
—
—
—
0
0
168
1581
1.47
1.02
6.4
6.8
41.29
41.13
mmol/mol
0.10
150
1448
18
116
1.61
1.01
2.1
2.3
331.78
389.01
nmol/l
0.70
18
110
5
23
2.20
0.98
2.4
1.4
—
—
—
0
0
24
167
1.50
0.98
2.1
1.5
—
—
—
0
0
38
291
1.38
0.95
1.2
1.2
1.30
1.56
u/ml
—
8
75
14
87
1.66
0.90
1.1
1.2
—
—
—
0
0
6
29
2.10
0.90
1.7
1.5
32.63
31.77
g/l
—
6
23
45
364
1.31
0.79
2.1
1.7
988.79
1149.51
nmol/l
0.70
35
272
0
27
0.00
0.78
0.0
3.2
—
—
—
0
0
0
27
0.00
0.78
0.0
3.2
—
4.04
—
0
27
0
27
0.00
0.78
0.0
3.2
—
104.81
—
0
27
16
108
1.52
0.76
1.6
1.9
—
—
—
0
0
24
179
1.39
0.71
1.8
1.5
—
—
—
0
0
14
95
1.51
0.66
1.1
1.3
—
—
—
0
0
0
21
0.00
0.60
0.0
4.6
—
56.19
—
0
21
9
61
1.50
0.54
1.1
1.1
—
—
—
0
0
9
61
1.50
0.54
2.2
1.9
—
—
—
0
0
109
1008
1.19
0.53
3.8
5.5
1.64
2.69
ug/l
2.44
95
891
43
501
0.82
0.52
2.3
3.4
—
—
—
0
0
14
101
1.42
0.51
2.2
2.3
1.39
1.20
%
0.40
14
101
7
48
1.48
0.47
1.6
2.4
—
—
—
0
0
7
50
1.41
0.45
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
2.3
—
2.86
—
0
15
0
15
0.00
0.41
0.0
1.1
—
310.07
—
0
15
0
15
0.00
0.41
0.0
1.1
—
149.09
—
0
15
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
286.00
—
0
9
52
583
0.85
0.41
2.4
3.2
0.58
0.79
ug/l
1.96
38
414
0
17
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
3.8
—
3.24
—
0
10
5
35
1.44
0.39
3.8
3.5
0.88
0.75
nmol/l
—
5
29
13
99
1.34
0.36
3.3
3.3
0.09
0.14
e6/l
0.25
13
99
7
98
0.70
0.31
1.7
2.4
—
19.53
—
0
7
7
98
0.70
0.31
4.3
3.2
—
—
—
0
0
7
54
1.31
0.30
2.1
2.6
—
—
—
0
0
80
753
1.11
0.25
2.2
2.0
95.22
91.78
pmol/l
0.18
44
366
0
11
0.00
0.21
0.0
1.2
—
8.13
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.6
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
6
48
1.26
0.20
1.0
1.5
56.50
58.12
%
—
6
48
38
348
1.11
0.20
5.6
3.8
1.02
1.02
kg/l
—
7
51
7
86
0.81
0.15
1.0
1.2
—
62.53
—
0
9
57
542
1.07
0.14
2.8
2.1
—
—
—
0
0
6
56
1.07
0.09
1.7
1.6
—
—
—
0
0
19
202
0.93
0.05
1.4
1.3
—
—
—
0
0
12
110
1.10
0.05
6.9
2.2
—
—
—
0
0
21
199
1.06
0.05
1.6
5.6
14.06
42.67
ug/l
0.56
16
170
10
99
1.01
0.00
2.3
2.2
0.49
0.65
%
—
10
99
49
493
0.99
0.00
1.8
1.6
1.67
1.30
mmol/l
1.26
38
393
14
145
0.96
0.00
2.1
2.7
4.73
4.39
kpa
0.24
14
139
14
138
1.02
0.00
3.3
3.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
1.43
—
0
6
0
8
0.00
-0.00
0.0
1.0
—
228.38
—
0
8
0
8
0.00
-0.00
0.0
1.3
—
6.80
—
0
8
0
5
0.00
-0.00
0.0
1.0
—
1447.80
—
0
5
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
8
0.00
-0.00
0.0
2.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.7
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
169.71
—
0
7
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
0.96
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
58
0.86
-0.00
7.0
11.6
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
5.26
—
0
5
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.2
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ILD_NINTENDANIB – ILD medications: nintedanib

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).