Crohn's disease: A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.
Crohn disease (strict definition, require KELA, min 2 HDR)
K11_CD_STRICT2
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditions
|
2897 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2701 |
4. Check minimum number of eventsNone |
2701 |
5. Include endpointsNone |
2701 |
6. Filter based on genotype QC (FinnGen only) |
2608 |
Control definitions (FinnGen only)
- Control conditions
- not K11_KELACROHN
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- K50-K52
- Name in latin
- Morbus Crohn
Similar endpoints
↥List of similar endpoints to
Crohn disease (strict definition, require KELA, min 2 HDR)
based on the number of shared cases.
Similar with more cases:
- Crohn disease (strict definition, require KELA)
- Crohn's disease patients in KELA-register (KELA code 209, or 208 with ICD K50)
- Crohn disease
- IBD patients in KELA-register
- Inflammatory bowel disease, strict (require KELA)
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12555 | 6354 | 6153 |
| Only index persons | 12138 | 6175 | 5963 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.18 | 0.18 | 0.17 |
| Only index persons | 0.23 | 0.23 | 0.23 |
| Median age at first event (years) | |||
| Whole population | 35.44 | 35.86 | 34.99 |
| Only index persons | 35.17 | 35.59 | 34.74 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2608 | 1507 | 1101 |
| Unadjusted period prevalence (%) | 0.52 | 0.53 | 0.50 |
| Median age at first event (years) | 39.40 | 38.12 | 41.15 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2701
- Matched controls
- 27010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
8.1
307.7
1605
4147
JF1AD
NOMESCO Finland
Small bowel CT
55.5
307.7
196
38
UJF30
NOMESCO Finland
Ileoscopy through colon
24.4
307.7
1483
1283
K50.9
ICD-10 Finland
Crohn disease, unspecified
380.5
307.7
1458
83
L04AB02
ATC
infliximab; parenteral
42.7
307.7
198
50
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
307.7
2701
512
256, ,
Kela drug reimbursment
204.3
307.7
190
10
L04AB04
ATC
adalimumab; parenteral
29.5
307.7
613
266
H02AB06
ATC
prednisolone; systemic
5.5
307.7
1938
8536
C10AC01
ATC
colestyramine; oral
16.1
307.7
344
242
A07EC02
ATC
mesalazine; oral, rectal
67.8
307.7
1693
653
K50.0
ICD-10 Finland
Crohn disease of small intestine
748.0
307.7
1848
78
ZX120
NOMESCO Finland
Intravenous
7.0
307.7
631
1129
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
217.1
307.7
201
10
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
14.6
307.7
461
376
L04AC05
ATC
ustekinumab; parenteral
89.0
307.7
258
32
A07EA06
ATC
budesonide; oral, local oral
134.2
307.7
1732
355
UJF92
NOMESCO Finland
Capsular endoscopy
55.3
307.7
775
195
JF1BD
NOMESCO Finland
Very extensive small bowel CT
75.6
307.7
203
29
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.9
307.7
1273
4153
L04AX01
ATC
azathioprine; systemic
78.5
307.7
1568
468
L04AX03
ATC
methotrexate; systemic
6.9
307.7
717
1345
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
13.0
307.7
461
420
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
125.9
307.7
849
98
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
126.0
307.7
332
30
K50.8
ICD-10 Finland
Other Crohn disease
605.0
307.7
1787
87
K50
ICD-10 Finland
Crohn disease [regional enteritis]
368.4
307.7
407
13
D94
ICPC
Chronic enteritis/ulcerative colitis
41.7
307.7
226
59
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
121.6
307.7
521
53
L01BB02
ATC
mercaptopurine; oral
70.4
307.7
595
108
K50.1
ICD-10 Finland
Crohn disease of large intestine
323.9
307.7
1195
66
UJF32
NOMESCO Finland
Coloscopy
20.0
307.7
2015
3456
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
26.0
276.7
194
80
JFB20
NOMESCO Finland
Ileocaecal resection
40.4
273.8
167
44
253, ,
Kela drug reimbursment
88.1
269.8
142
17
3042, ,
Kela drug reimbursment
88.1
269.8
142
17
P01AB01
ATC
metronidazole; oral, rectal
4.0
268.1
1617
7389
A07EC01
ATC
sulfasalazine; oral, rectal
5.9
250.9
516
1040
4AA12, ,
NOMESCO Finland
46.7
248.2
146
33
L04AA33
ATC
[U] vedolizumab
115.1
237.0
121
11
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
12.6
235.8
238
205
K51.5
ICD-10 Finland
Left sided colitis
9.2
235.0
301
363
4AB02, ,
NOMESCO Finland
43.4
234.0
140
34
A07EA02
ATC
hydrocortisone; rectal
11.9
228.1
239
218
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
8.6
225.1
305
394
JFB00
NOMESCO Finland
Partial resection of small intestine
19.2
205.4
163
90
J01MA02
ATC
ciprofloxacin; systemic
3.3
203.1
1344
6205
H02AB07
ATC
prednisone; oral
4.4
200.5
615
1712
K51.8
ICD-10 Finland
Other ulcerative colitis
13.6
199.9
191
150
JN3BD
NOMESCO Finland
Extensive abdominal CT
4.9
196.8
496
1182
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.2
188.1
1444
7182
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
22.1
187.0
139
66
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
16.9
186.3
157
98
B03BA03
ATC
hydroxocobalamin; parenteral
7.6
185.9
278
401
L04AG05
ATC
vedolizumab; parenteral
76.5
178.8
96
13
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
27.0
173.1
119
46
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
165.2
1398
7191
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
20.0
153.6
119
62
WX002
NOMESCO Finland
Sedation and analgesia
3.4
151.3
711
2600
K60.3
ICD-10 Finland
Anal fistula
9.9
150.3
178
192
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
136.7
785
3206
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
4.6
134.3
351
850
UJF02
NOMESCO Finland
Peroral enteroscopy
29.0
129.8
87
31
JX1LA
NOMESCO Finland
Kinetic X-ray of alimentary tract with pictures
53.6
127.8
73
14
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
8.7
125.9
163
197
NK6QA
NOMESCO Finland
Measurement of bone density from two or more locations with X-ray
4.9
123.2
295
664
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
11.1
122.7
132
124
B81
ICPC
Anaemia vit B12/folate deficiency
7.3
116.0
175
253
K56.7
ICD-10 Finland
Ileus, unspecified
12.2
115.7
117
100
A02BC02
ATC
pantoprazole; systemic
2.6
107.7
1924
13208
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
3.1
107.5
538
2005
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
4.1
100.2
300
800
WVA20
NOMESCO Finland
Medicine administration
6.6
99.3
165
264
JHA00
NOMESCO Finland
Anal or perianal incision
8.2
99.2
135
173
A06AC01
ATC
ispaghula (psylla seeds); oral
2.5
93.9
756
3582
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.5
93.1
742
3497
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
10.0
92.6
107
111
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.4
91.8
371
1209
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.0
91.4
487
1867
M45
ICD-10 Finland
Ankylosing spondylitis
6.5
89.8
150
241
K61.0
ICD-10 Finland
Anal abscess
7.0
88.2
138
207
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
88.1
406
1431
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
33.0
85.5
55
17
107
Kela drug reimbursment
Pernicious anaemia
9.9
85.5
99
103
K83.0
ICD-10 Finland
Cholangitis
9.9
85.5
99
103
N02AX02
ATC
tramadol; systemic, rectal
2.2
84.1
1206
7253
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
43.5
78.5
47
11
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.3
77.9
214
533
JHD30
NOMESCO Finland
Incomplete incision of fistula-in-ano
22.9
76.7
56
25
3AC01, ,
NOMESCO Finland
11.3
76.5
81
74
L01BA01
ATC
methotrexate; systemic
4.8
72.5
168
365
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
716.8
71.4
70
*
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
89.3
70.3
78
9
JFB21
NOMESCO Finland
Laparoscopic ileocaecal resection
99.1
70.3
77
8
A02BC01
ATC
omeprazole; systemic
2.2
70.0
758
4015
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
356.3
69.9
70
*
JFB30
NOMESCO Finland
Right hemicolectomy
11.6
65.7
68
60
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.6
63.6
82
98
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.9
63.0
194
524
A02BC03
ATC
lansoprazole; oral
2.1
62.8
756
4149
WW200
NOMESCO Finland
Immunization
4.9
62.7
144
310
Z93.2
ICD-10 Finland
Ileostomy status
20.3
62.7
48
24
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
60.7
420
1817
JHD33
NOMESCO Finland
Completing incision of fistula-in-ano
20.8
59.3
45
22
D64.9
ICD-10 Finland
Anaemia, unspecified
3.1
56.5
257
890
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
56.4
678
3697
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
7.0
56.1
86
126
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
55.8
750
4261
JAH00
NOMESCO Finland
Laparotomy
5.3
54.0
111
217
UJD02
NOMESCO Finland
Gastroscopy
3.8
51.7
162
442
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.1
51.6
110
222
R50.9
ICD-10 Finland
Fever, unspecified
2.2
51.4
485
2395
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.5
50.4
345
1478
JHD20
NOMESCO Finland
Incision of fistula-in-ano
7.8
49.8
69
90
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
20.3
49.5
38
19
A05AA02
ATC
ursodeoxycholic acid; oral
5.2
48.7
101
199
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.7
48.1
290
1166
4AA33, ,
NOMESCO Finland
78.8
48.1
54
7
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
48.0
229
813
H02AB09
ATC
hydrocortisone; systemic
4.5
47.0
118
273
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
88.4
47.0
52
6
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
5.1
46.8
101
206
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
46.5
192
627
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
3.0
45.6
218
775
XJW99
NOMESCO Finland
Other investigative procedure on digestive system
17.8
45.5
37
21
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.6
44.3
107
240
N02BE01
ATC
paracetamol; systemic, rectal
2.3
44.0
2358
20326
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
3.5
43.9
159
478
K29.8
ICD-10 Finland
Duodenitis
10.0
43.7
50
51
JF1DM
NOMESCO Finland
Very extensive MRI of small bowel (more than 1.5 T)
223.6
43.0
44
*
A02BC05
ATC
esomeprazole; systemic
1.8
42.7
1038
7024
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.8
42.2
232
888
K92.1
ICD-10 Finland
Melaena
3.5
42.0
147
432
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.6
40.5
98
220
K59.1
ICD-10 Finland
Functional diarrhoea
3.0
40.3
193
686
WZC30
NOMESCO Finland
Teaching
2.1
39.9
423
2172
5550A
ICD-9 Finland
Regional enteritis, Small intestine
109.2
39.8
43
*
J01MA12
ATC
levofloxacin; systemic
2.1
39.7
448
2354
A06AC51
ATC
ispaghula, combinations; oral
3.3
39.1
154
488
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.0
39.0
509
2817
D01
ICPC
Abdominal pain/cramps general
2.1
38.1
395
2008
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.7
37.9
89
195
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.6
37.9
245
1016
1370
FHL
Colonoscopy, whole colon
12.5
37.6
37
30
JF1CM
NOMESCO Finland
Small bowel extensive MRI with with high intensity magnet
70.9
37.0
42
6
5551A
ICD-9 Finland
Regional enteritis, Large intestine
192.6
36.9
38
*
C05AA08
ATC
fluocortolone; rectal, topical
2.2
36.8
350
1718
WX402
NOMESCO Finland
General anaesthesia
1.8
35.3
606
3658
UJF30, ,
SPAT
7.0
35.2
54
79
K61.1
ICD-10 Finland
Rectal abscess
11.8
35.2
36
31
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
34.6
1153
8370
J01DB01
ATC
cefalexin; oral
1.9
34.4
2251
19521
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.4
34.3
254
1120
L04AF03
ATC
upadacitinib; oral
13.5
34.0
32
24
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
8.2
33.7
45
56
A07AA09
ATC
vancomycin; oral
6.5
33.7
55
86
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.6
33.7
80
177
ZX112
NOMESCO Finland
Subcutaneous
4.5
33.5
83
190
K29.7
ICD-10 Finland
Gastritis, unspecified
3.5
33.1
116
341
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
33.0
705
4532
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
32.7
386
2053
K56.0
ICD-10 Finland
Paralytic ileus
8.0
32.4
44
56
A07DA03
ATC
loperamide; oral
3.9
32.3
97
257
A02BA02
ATC
ranitidine; systemic
2.0
32.1
424
2344
5552A
ICD-9 Finland
Regional enteritis, Small intestine with large intestine
62.5
32.1
37
6
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
320.8
31.9
32
*
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
5.7
31.8
59
105
ZXE00
NOMESCO Finland
One hour or less
1.6
31.5
1009
7202
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
31.3
563
3433
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.8
30.5
93
249
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
11.2
30.2
32
29
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
6.2
30.1
51
83
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
3.1
30.0
128
425
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
29.9
1174
8775
UJH02
NOMESCO Finland
Anoscopy
3.0
29.1
129
438
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
4.6
28.8
69
154
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
28.6
903
6388
J05AB11
ATC
valaciclovir; oral
1.9
28.4
384
2133
ZXD05
NOMESCO Finland
Urgent procedure
1.6
28.4
798
5482
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.6
28.3
977
7056
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
28.2
1123
8387
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
27.9
841
5873
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.7
27.7
89
247
K65.0
ICD-10 Finland
Acute peritonitis
6.8
27.6
43
64
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.6
26.8
866
6138
4AC05, ,
NOMESCO Finland
273.7
26.8
27
*
D07AC01
ATC
betamethasone; topical
1.6
26.7
884
6303
JAH01
NOMESCO Finland
Laparoscopy
2.7
26.7
144
545
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.8
26.6
83
226
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
26.4
523
3263
B02.9
ICD-10 Finland
Zoster without complication
2.6
26.2
159
638
E0000UV, ,
ATC
1.6
26.0
1092
8207
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
8.0
26.0
35
44
K60.2
ICD-10 Finland
Anal fissure, unspecified
3.9
25.1
73
189
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.8
25.1
46
81
L52
ICD-10 Finland
Erythema nodosum
6.8
25.1
39
58
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.4
24.9
178
771
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
3.7
24.9
78
213
B80
ICPC
Iron deficiency anaemia
3.5
24.7
87
257
L02.3
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of buttock
3.3
24.2
91
280
JH1CM
NOMESCO Finland
Perianal extensive MRI with 3 Tesla magnet
56.5
24.0
28
5
D07XC01
ATC
betamethasone; topical
2.0
24.0
297
1598
M05BA04
ATC
alendronic acid; oral
2.6
23.9
148
600
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.7
23.8
55
119
JFA60
NOMESCO Finland
Stricturoplasty in small intestine
242.1
23.7
24
*
WX004
NOMESCO Finland
Patient-controlled sedation
9.4
23.5
28
30
H02AB04
ATC
methylprednisolone; systemic
1.9
23.1
341
1942
D99
ICPC
Disease digestive system other
5.5
22.9
44
81
WZC00
NOMESCO Finland
Treatment plan or consultation
1.5
22.8
945
7030
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.0
22.7
103
355
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.9
22.7
107
377
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.5
22.5
78
228
A03CA02
ATC
clidinium and psycholeptics; oral
2.7
22.3
120
453
UJF34
NOMESCO Finland
Left colonoscopy
8.4
22.3
29
35
D50.8
ICD-10 Finland
Other iron deficiency anaemias
4.6
22.2
52
114
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
24.1
22.2
31
13
J02AC01
ATC
fluconazole; systemic
1.5
22.0
988
7461
R11
ICD-10 Finland
Nausea and vomiting
2.0
22.0
239
1227
K60.1
ICD-10 Finland
Chronic anal fissure
3.3
21.6
82
254
WW500
NOMESCO Finland
Blood transfusion
2.8
20.9
104
377
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
20.9
535
3551
B01AB05
ATC
enoxaparin; parenteral
1.6
20.9
653
4548
K60.0
ICD-10 Finland
Acute anal fissure
4.5
20.8
50
112
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.9
20.7
96
335
S01BA01
ATC
dexamethasone; ophthalmic
3.0
20.6
93
320
R4190
NOMESCO Finland
Nutritional therapy
2.6
20.5
121
479
S18
ICPC
Laceration/cut
1.5
20.4
1024
7880
Z93.3
ICD-10 Finland
Colostomy status
7.0
20.4
31
45
R10.0
ICD-10 Finland
Acute abdomen
2.8
20.2
102
373
Z3231
NOMESCO Finland
Registered nurse
1.6
19.8
641
4491
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
5.5
19.8
38
70
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.8
19.7
350
2104
UJG02
NOMESCO Finland
Proctoscopy
3.7
19.7
63
175
UJK02
NOMESCO Finland
ERCP
3.6
19.4
64
181
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.6
19.4
64
181
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
19.1
145
645
D07AD01
ATC
clobetasol; topical
1.7
19.1
389
2429
WX610
NOMESCO Finland
Patient controlled analgesia
5.5
18.8
36
66
Z2221
NOMESCO Finland
Medical doctor
1.5
18.8
675
4832
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
6.0
18.7
33
56
M01AH01
ATC
celecoxib; oral
1.7
18.6
366
2262
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
4.7
18.5
42
90
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
18.4
726
5294
D11
ICPC
Diarrhoea
1.7
18.3
358
2211
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
3.4
18.2
66
199
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
18.2
1478
12361
E86
ICD-10 Finland
Volume depletion
3.9
18.1
53
138
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
5.7
18.0
33
58
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
3.8
18.0
55
148
JFF13
NOMESCO Finland
Terminal enterostomy
15.4
17.9
29
19
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
17.8
286
1667
K60.4
ICD-10 Finland
Rectal fistula
18.2
17.8
27
15
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
17.6
129
565
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
4.3
17.6
45
106
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
17.6
1916
16862
L40.0
ICD-10 Finland
Psoriasis vulgaris
2.4
17.6
121
516
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
17.5
249
1399
J05AB01
ATC
aciclovir; systemic
1.6
17.4
524
3597
TJF80
NOMESCO Finland
Ostomy education
5.9
17.4
31
53
K30
ICD-10 Finland
Functional dyspepsia
1.8
17.3
284
1665
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
2.3
17.3
138
627
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
17.3
257
1464
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
31.7
17.0
22
7
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.9
17.0
50
131
J01FF01
ATC
clindamycin; systemic
1.5
17.0
632
4544
KH1AD
NOMESCO Finland
CT of urinary organs
2.7
16.8
90
340
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
63.7
16.7
19
*
TQW99
NOMESCO Finland
Other minor procedure on skin
2.5
16.7
109
453
SPAT1153
SPAT
Removal of sutures
1.5
16.7
650
4714
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
35.3
16.7
21
6
SPAT1263
SPAT
Sampling
1.4
16.7
1029
8148
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.9
16.6
80
286
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.8
16.3
264
1541
JEA00
NOMESCO Finland
Appendectomy
2.0
16.3
183
950
SPAT1255
SPAT
Intravenous administration of medicine
2.1
16.2
150
725
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
16.1
223
1241
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.1
15.8
67
223
ZYC01
NOMESCO Finland
Remote contact by phone
2.0
15.7
171
877
J01AA02
ATC
doxycycline; systemic
1.4
15.6
1824
16048
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
15.6
165
838
JFF10
NOMESCO Finland
Loop enterostomy
6.1
15.6
27
45
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
15.6
262
1547
JF1CD
NOMESCO Finland
Extensive small bowel CT
85.6
15.6
17
*
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
15.6
186
986
K63.2
ICD-10 Finland
Fistula of intestine
19.3
15.5
23
12
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
3.8
15.5
47
126
A03FA02
ATC
cisapride; oral, rectal
2.1
15.5
149
731
L73.8
ICD-10 Finland
Other specified follicular disorders
4.1
15.4
42
104
S01FA02
ATC
scopolamine; ophthalmic
5.8
15.4
28
49
K85
ICD-10 Finland
Acute pancreatitis
3.8
15.4
46
122
JJ1LE
NOMESCO Finland
Ultrasound elastography of liver
4.2
15.3
40
96
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
15.2
427
2877
QBA10
NOMESCO Finland
Incision of skin of trunk
4.2
15.1
39
93
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
6.8
14.9
23
34
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.9
14.8
43
112
6404
FHL
Hemicolectomy on the right
+∞
14.6
14
*
JFA96
NOMESCO Finland
Other local operation on intestine
80.6
14.6
16
*
5559X
ICD-9 Finland
Regional enteritis, Unspecified site
80.6
14.6
16
*
L04AB06
ATC
golimumab; parenteral
4.3
14.5
37
87
Z93
ICD-10 Finland
Artificial opening status
14.2
14.5
24
17
M50.8
ICD-10 Finland
Other cervical disc disorders
6.6
14.5
23
35
Z01.2
ICD-10 Finland
Dental examination
1.4
14.4
1209
10012
JFB01
NOMESCO Finland
Laparoscopic partial resection of small intestine
27.3
14.3
19
7
E000001, ,
ATC
1.5
14.2
504
3570
B03BA02
ATC
cyanocobalamin tannin complex; parenteral
12.0
14.1
25
21
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.2
14.0
122
575
D07AC13
ATC
mometasone; topical
1.4
14.0
672
5049
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
14.0
172
920
M81.4
ICD-10 Finland
Drug-induced osteoporosis
11.5
13.8
25
22
B07.9
ICD-10 Finland
Verruca simplex
2.2
13.7
110
502
K51
ICD-10 Finland
Ulcerative colitis
3.6
13.7
44
123
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
2.5
13.5
85
348
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.7
13.5
246
1485
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
13.5
240
1439
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.1
13.5
123
591
JFB96
NOMESCO Finland
Other partial excision of intestine
140.7
13.5
14
*
M25.5
ICD-10 Finland
Pain in joint
1.4
13.4
784
6094
R51.80
ICD-10 Finland
Headache
1.5
13.4
418
2879
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
13.4
145
743
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.6
13.4
79
314
JKA20
NOMESCO Finland
Cholecystectomy
3.2
13.3
53
170
D06BX01
ATC
metronidazole; topical
1.7
13.2
243
1472
JN2BG
NOMESCO Finland
MRI examination of lower part of abdoment with high intensity magnet
5.1
13.2
27
53
6403
FHL
Ileocal resection
40.3
13.1
16
*
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.0
13.1
149
776
J01DA01
ATC
[U] cefalexin
1.4
13.1
1497
12928
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
13.1
207
1200
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.5
13.1
31
69
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
13.0
226
1347
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
9.4
13.0
26
28
JFH10
NOMESCO Finland
Total colectomy and ileostomy
19.1
12.9
19
10
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
12.8
234
1415
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
12.7
461
3277
S10
ICPC
Boil/carbuncle
2.0
12.6
147
773
A02BA03
ATC
famotidine; systemic
2.7
12.6
66
247
L40.8
ICD-10 Finland
Other psoriasis
4.8
12.6
28
59
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
5.5
12.6
24
44
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
6.2
12.5
21
34
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.7
12.4
65
244
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
12.4
433
3054
R03AC02
ATC
salbutamol; inhalant
1.3
12.3
1364
11676
L04AC18
ATC
risankizumab; parenteral
11.7
12.3
22
19
RD210, ,
NOMESCO Finland
2.8
12.3
59
211
6455
FHL
Perianal fistula surgery
9.0
12.2
25
28
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
4.3
12.2
31
73
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
3.0
12.1
52
175
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
2.8
12.0
58
208
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.3
12.0
87
381
L04AD01
ATC
ciclosporin; systemic
2.8
12.0
57
203
L88
ICD-10 Finland
Pyoderma gangrenosum
13.4
11.9
20
15
D95
ICPC
Anal fissure/perianal abscess
3.8
11.9
35
92
A01AB09
ATC
miconazole; local oral
1.8
11.9
176
1000
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
2.5
11.9
73
296
L88
ICPC
Rheumatoid/seropositive arthritis
2.3
11.9
92
414
N06AX11
ATC
mirtazapine; oral
1.4
11.9
772
6085
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
3.1
11.8
48
156
H20.1
ICD-10 Finland
Chronic iridocyclitis
3.8
11.7
35
93
K02.1
ICD-10 Finland
Caries of dentine
1.3
11.7
1603
14112
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
30.2
11.6
15
5
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
30.2
11.6
15
5
JN2DG
NOMESCO Finland
Very extensive MRI examination of lower part of abdoment with high intensity magnet
3.9
11.6
34
89
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.7
11.6
59
218
JHA20
NOMESCO Finland
Excision of lesion of anal canal or perianal tissue
3.6
11.6
38
108
6402
FHL
Small bowel resection
23.0
11.6
16
7
L73.2
ICD-10 Finland
Hidradenitis suppurativa
3.2
11.5
45
143
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
15.1
11.3
18
12
JFA70
NOMESCO Finland
Suture of small intestine
8.9
11.2
23
26
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.7
11.2
227
1409
J01DA09
ATC
[U] cefadroxil
1.4
11.2
630
4841
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.1
11.2
110
545
N03AX16
ATC
[U] pregabalin
1.4
11.2
476
3484
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
11.1
1335
11497
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
11.1
821
6594
D06
ICPC
Abdominal pain localized other
1.7
11.0
205
1244
298, ,
Kela drug reimbursment
8.6
11.0
23
27
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
10.8
87
399
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
4.7
10.7
24
51
JN4AD
NOMESCO Finland
Body CT examination
1.8
10.7
177
1040
A06AD11
ATC
lactulose; oral
1.6
10.6
228
1438
3029
Kela drug reimbursment
Upadacitinib
8.0
10.6
23
29
D05AX52
ATC
calcipotriol, combinations; topical
1.9
10.5
122
641
N05CF02
ATC
zolpidem; oral
1.5
10.5
392
2794
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
10.5
172
1008
D51.9
ICD-10 Finland
Vitamin B12deficiency anaemia, unspecified
4.8
10.5
23
48
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.9
10.4
48
168
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
10.4
2137
22708
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
10.4
1826
16509
JK3MN
NOMESCO Finland
Bile absorbtion isotope examination
32.6
10.3
13
*
B02
ICD-10 Finland
Zoster [herpes zoster]
2.1
10.3
96
466
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.7
10.3
53
197
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
5.2
10.3
21
41
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.3
1911
17396
M54.5
ICD-10 Finland
Low back pain
1.3
10.2
863
7047
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.0
10.2
28
70
ZX114
NOMESCO Finland
Intramuscular
3.0
10.2
44
149
UKC02
NOMESCO Finland
Cystoscopy
1.6
10.1
248
1614
WZC10
NOMESCO Finland
Written specialist consultation based on a referral from a dentist or a physician
2.0
10.1
112
580
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
10.0
398
2871
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
1.9
10.0
115
603
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
4.8
10.0
22
46
4AA17, ,
NOMESCO Finland
40.2
10.0
12
*
M03BX02
ATC
tizanidine; oral
1.3
9.9
1523
13469
S01BA04
ATC
prednisolone; ophthalmic
2.8
9.9
48
173
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
9.8
183
1111
H15.1
ICD-10 Finland
Episcleritis
2.9
9.7
44
153
J01FA10
ATC
azithromycin; systemic
1.3
9.7
1522
13481
JHD10
NOMESCO Finland
Myotomy of anal sphincter
5.3
9.6
19
36
A02BX02
ATC
sucralfate; oral
2.3
9.6
68
295
K13.78
ICD-10 Finland
Other change in the oral mucosa
2.6
9.6
56
222
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.2
9.6
80
372
M79.7
ICD-10 Finland
Fibromyalgia
2.1
9.6
88
425
S29
ICPC
Skin symptom/complaint other
1.4
9.5
398
2896
T91
ICPC
Vitamin/nutritional deficiency
4.6
9.5
22
48
A07EC03
ATC
olsalazine; oral
15.1
9.5
15
10
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
3.6
9.5
31
88
J01FA06
ATC
roxithromycin; oral
1.3
9.5
863
7106
R06AE07
ATC
cetirizine; oral
1.3
9.5
1100
9358
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.6
9.4
219
1408
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.1
9.4
87
422
R2110
NOMESCO Finland
Giving the first information
1.8
9.4
153
896
Z94.4
ICD-10 Finland
Liver transplant status
5.2
9.4
19
37
K63.8
ICD-10 Finland
Other specified diseases of intestine
12.4
9.3
16
13
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.9
9.3
106
555
7200A
ICD-9 Finland
Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis
8.7
9.3
19
22
UJK12
NOMESCO Finland
Peroral cholangioscopy
10.7
9.3
17
16
D07BC01
ATC
betamethasone and antiseptics; topical
1.6
9.3
246
1632
SHA01
NOMESCO Finland
Stomatognathic treatment, simple
1.5
9.2
282
1928
A07AA02
ATC
nystatin; oral
1.9
9.1
106
558
K03.66
ICD-10 Finland
Tooth plaque
1.7
9.1
176
1079
XF400
NOMESCO Finland
ECG with 12 standard connections
1.5
9.1
279
1909
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.8
9.1
142
821
B82
ICPC
Anaemia other/unspecified
2.6
9.1
51
199
JGB30
NOMESCO Finland
Abdominoperineal excision of rectum
11.5
9.1
16
14
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
15.6
9.0
14
9
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
9.0
283
1949
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.8
8.9
130
736
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
4.2
8.9
23
55
R07.0
ICD-10 Finland
Pain in throat
1.6
8.9
190
1196
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
8.9
276
1893
N06AX21
ATC
duloxetine; oral
1.5
8.9
268
1828
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
1.9
8.9
107
571
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
8.9
1370
12050
J01CA04
ATC
amoxicillin; systemic
1.4
8.9
2160
20167
N07BA03
ATC
varenicline; oral
1.8
8.8
124
695
A03
ICPC
Fever
1.4
8.8
467
3543
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
8.7
205
1321
S21
ICPC
Skin texture symptom/complaint
1.5
8.7
283
1959
WX290
NOMESCO Finland
Other blockage of nerve
1.3
8.7
1312
11494
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
3.1
8.7
36
119
K63.0
ICD-10 Finland
Abscess of intestine
14.1
8.7
14
10
SPAT1325
SPAT
Vaccination
1.3
8.7
645
5151
A04AA01
ATC
ondansetron; systemic, rectal
1.7
8.7
153
917
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.6
8.6
176
1095
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
2.2
8.6
69
316
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
8.6
313
2216
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
8.6
629
5010
56510
ICD-8 Finland
Anal fissure and fistula, Anal fistula
11.6
8.6
15
13
JN2AD
NOMESCO Finland
CT examination of lower part of abdomen
9.0
8.5
17
19
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
1.3
8.5
579
4562
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
3.3
8.5
31
95
R01AD12
ATC
fluticasone furoate; nasal
1.3
8.5
822
6807
ZY010
NOMESCO Finland
Hospital outpatient
1.7
8.5
150
900
M01AH02
ATC
rofecoxib; oral
1.6
8.4
206
1341
M79.6
ICD-10 Finland
Pain in limb
1.3
8.4
936
7888
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
4.5
8.4
20
45
SFA20
NOMESCO Finland
Two-surface restoration
1.3
8.3
1504
13436
SFA10
NOMESCO Finland
One-surface restoration
1.3
8.3
1414
12539
K61.2
ICD-10 Finland
Anorectal abscess
8.5
8.3
17
20
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
8.3
214
1411
M79.1
ICD-10 Finland
Myalgia
1.4
8.3
346
2516
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
8.2
76
369
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.2
8.2
65
297
OAB93, ,
SPAT
1.6
8.2
170
1063
JFB43
NOMESCO Finland
Left hemicolectomy
6.5
8.2
20
31
L57.0
ICD-10 Finland
Actinic keratosis
1.8
8.1
129
750
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
3.1
8.1
33
108
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
0.6
8.1
186
2812
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
2.5
8.1
47
187
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.1
8.1
70
332
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.1
8.0
74
359
E000002, ,
ATC
1.5
8.0
265
1841
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
8.9
8.0
16
18
D82
ICPC
Teeth/gum disease
1.3
8.0
964
8190
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
8.0
117
664
H22.1*M45
ICD-10 Finland
Iridocyclitis in ankylosing spondylitis
10.0
8.0
15
15
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
10.0
8.0
15
15
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
8.0
291
2061
SPAT1312
SPAT
General health counselling
1.3
8.0
750
6177
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
7.2
8.0
18
25
A02BA04
ATC
nizatidine; systemic
1.8
7.9
117
666
K92.0
ICD-10 Finland
Haematemesis
2.5
7.9
46
183
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
7.9
214
1426
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
4.4
7.9
19
43
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.0
7.9
78
389
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
7.8
1170
10196
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.3
7.8
543
4289
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
1.8
7.8
113
641
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.0
7.8
82
419
A02BC04
ATC
rabeprazole; oral
1.6
7.8
195
1278
M01AX17
ATC
nimesulide; oral
1.4
7.7
406
3068
D22.9
ICD-10 Finland
Melanocytic naevi, unspecified
1.7
7.7
125
731
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
4.2
7.7
20
48
L20.0
ICD-10 Finland
Besnier prurigo
1.5
7.7
213
1425
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.7
393
2957
B01AB10
ATC
tinzaparin; parenteral
1.6
7.7
186
1208
6451
FHL
Dilatation
4.3
7.7
19
44
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
7.7
119
688
K29.6
ICD-10 Finland
Other gastritis
3.3
7.7
28
86
F45.0
ICD-10 Finland
Somatization disorder
4.5
7.6
18
40
K59.8
ICD-10 Finland
Other specified functional intestinal disorders
4.5
7.6
18
40
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.3
7.6
496
3878
K85.3
ICD-10 Finland
Drug-induced acute pancreatitis
18.4
7.6
11
6
K90.4
ICD-10 Finland
Malabsorption due to intolerance, not elsewhere classified
18.4
7.6
11
6
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
2.0
7.6
78
395
JFC20
NOMESCO Finland
Other enterocolostomy
25.1
7.6
10
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
7.5
900
7628
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.5
7.5
219
1484
ZXH04
NOMESCO Finland
Procedure performed in other inpatient unit
4.2
7.5
19
45
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
4.2
7.5
19
45
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
7.5
531
4204
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
2.5
7.4
45
183
UDC00
NOMESCO Finland
Ear microscopy
1.6
7.4
156
980
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.7
7.4
132
794
D13.3
ICD-10 Finland
Benign neoplasm: Other and unspecified parts of small intestine
7.7
7.4
16
21
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.8
7.4
114
659
JAD10
NOMESCO Finland
Repair of incisional hernia
4.0
7.3
20
50
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
2.5
7.3
43
172
S01GX01
ATC
cromoglicic acid; ophthalmic
1.3
7.3
495
3889
K76.9
ICD-10 Finland
Liver disease, unspecified
2.9
7.3
33
115
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
1.9
7.3
82
428
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
1.9
7.3
84
443
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
2.7
7.2
36
133
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.2
1404
12565
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
30.1
7.1
9
*
1380
FHL
Colonoscopy, left side
20.1
7.1
10
5
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.2
7.1
58
269
QBE15
NOMESCO Finland
Excision of other superficial lesion of skin of trunk
6.6
7.1
17
26
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
1.9
7.1
84
447
L04AA01
ATC
[U] ciclosporin
3.0
7.1
30
101
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
12.0
7.1
12
10
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.3
7.1
49
212
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
1.7
7.1
134
820
K63.9
ICD-10 Finland
Disease of intestine, unspecified
5.6
7.1
19
34
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.5
7.0
213
1454
N32.1
ICD-10 Finland
Vesicointestinal fistula
8.8
7.0
14
16
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.1
7.0
61
290
LFB00
NOMESCO Finland
Biopsy of vulva or perineum
2.3
7.0
50
219
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
3.6
7.0
22
61
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
2.4
7.0
44
182
R52.9
ICD-10 Finland
Pain, unspecified
1.5
7.0
201
1357
R06.0
ICD-10 Finland
Dyspnoea
1.3
7.0
486
3832
K13.00
ICD-10 Finland
Cheilitis NOS
3.9
7.0
20
52
K75.9
ICD-10 Finland
Inflammatory liver disease, unspecified
3.0
7.0
30
102
JN2CM
NOMESCO Finland
Lower part of abdomen extensive MRI examination with Tesla magnet
4.4
7.0
17
39
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
4.4
7.0
17
39
A07EA01
ATC
prednisolone; oral, rectal
6.3
6.9
17
27
R60.0
ICD-10 Finland
Localized oedema
1.5
6.9
196
1320
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
5.8
6.9
18
31
SBB00
NOMESCO Finland
Clinical photography of mouth and teeth
1.8
6.9
90
495
WVA30, ,
SPAT
1.8
6.9
101
576
N05BA04
ATC
oxazepam; oral
1.3
6.9
540
4332
TEA00
NOMESCO Finland
Biopsy of lip
3.4
6.8
24
72
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
2.3
6.8
50
222
R87.6
ICD-10 Finland
Abnormal findings in specimens from female genital organs, abnormal cytological findings
1.5
6.8
212
1456
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
2.4
6.8
46
197
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
3.8
6.8
20
53
D28
ICPC
Limited function/disability (D)
9.3
6.8
13
14
E78.0
ICD-10 Finland
Pure hypercholesterolaemia
0.7
6.8
206
2943
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.6
6.8
139
869
JFG26
NOMESCO Finland
Closure of terminal enterostomy with anastomosis to colon
40.2
6.8
8
*
4AB04, ,
NOMESCO Finland
40.2
6.8
8
*
M05BB03
ATC
alendronic acid and colecalciferol; oral
2.8
6.7
32
115
LEB00
NOMESCO Finland
Biopsy of vagina
2.7
6.7
35
132
SPAT1260
SPAT
Consultation of another employee
1.4
6.7
349
2632
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
6.7
522
4179
N20.1
ICD-10 Finland
Calculus of ureter
2.0
6.7
72
371
D07AB08
ATC
desonide; topical
1.5
6.7
236
1662
L02.2
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of trunk
1.8
6.7
104
603
WX892
NOMESCO Finland
Monitored bed care
1.6
6.7
133
825
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.6
607
4964
L71.9
ICD-10 Finland
Rosacea, unspecified
2.2
6.6
54
251
A55
ICPC
General and Unspecified, Local injection/infiltration
2.7
6.6
33
122
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
5.5
6.6
18
33
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.5
6.6
39
157
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
6.6
120
727
SDA02
NOMESCO Finland
Periodontal treatment, brief
1.3
6.6
842
7168
ULA02
NOMESCO Finland
Kolposcopy
1.5
6.6
216
1500
E87.6
ICD-10 Finland
Hypokalaemia
2.1
6.6
62
305
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
4.2
6.5
17
41
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.5
1011
8791
N20.9
ICD-10 Finland
Urinary calculus, unspecified
2.1
6.5
55
259
JJC00
NOMESCO Finland
Allogenic transplantation of liver
6.8
6.5
15
22
J02.9
ICD-10 Finland
Acute pharyngitis, unspecified
1.6
6.5
162
1061
AA1AD
NOMESCO Finland
CT of head and brain
1.3
6.5
441
3464
A02BB01
ATC
misoprostol; oral
5.3
6.5
18
34
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.4
593
4851
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
5.7
6.4
17
30
SPAT1254
SPAT
Administration of medicine
1.4
6.4
285
2092
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
1.8
6.4
84
462
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.5
6.4
21
60
H57.1
ICD-10 Finland
Ocular pain
1.8
6.4
89
499
N06AX16
ATC
venlafaxine; oral
1.4
6.4
341
2581
E000007, ,
ATC
1.7
6.4
123
756
SCA02
NOMESCO Finland
Preventive oral health care
1.4
6.4
277
2026
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
1.9
6.4
78
420
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
6.4
171
1138
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
3.7
6.4
19
51
K56.2
ICD-10 Finland
Volvulus
4.1
6.4
17
42
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.4
6.3
263
1909
R06AX27
ATC
desloratadine; oral
1.3
6.3
727
6108
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
1.9
6.3
75
400
K29.4
ICD-10 Finland
Chronic atrophic gastritis
2.8
6.3
30
108
EB4VA, ,
NOMESCO Finland
1.4
6.3
269
1962
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.5
6.3
218
1530
JA3BT
NOMESCO Finland
Cathetrisation of abdominal cavity with X-ray guidance
5.5
6.3
17
31
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
9.3
6.3
12
13
JHD96
NOMESCO Finland
Other incision of anal sphincter
9.3
6.3
12
13
JHC60
NOMESCO Finland
Transanal submucous or intersphincteric injection
9.3
6.3
12
13
K80.8
ICD-10 Finland
Other cholelithiasis
2.5
6.3
38
155
392
Kela drug reimbursment
Ferric maltol
+∞
6.3
6
*
R01AD58
ATC
fluticasone, combinations; nasal
1.3
6.2
624
5156
K83.1
ICD-10 Finland
Obstruction of bile duct
3.0
6.2
26
87
R05FA02
ATC
opium derivatives and expectorants; systemic
1.2
6.2
832
7111
L40.3
ICD-10 Finland
Pustulosis palmaris et plantaris
2.6
6.2
35
138
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
3.7
6.2
19
52
A98
ICPC
Health maint/preventive medicine
1.8
6.2
2616
25553
L21.8
ICD-10 Finland
Other seborrhoeic dermatitis
2.7
6.2
31
115
5651A
ICD-9 Finland
Anal fissure and fistula, Anal fistula[FISTULA ANI]
6.3
6.2
15
24
WX419
NOMESCO Finland
Other general anesthesy
3.2
6.1
23
72
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.1
348
2660
A04.9
ICD-10 Finland
Bacterial intestinal infection, unspecified
3.4
6.1
21
62
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
7.7
6.1
13
17
K90.9
ICD-10 Finland
Intestinal malabsorption, unspecified
7.7
6.1
13
17
L98.9
ICD-10 Finland
Disorder of skin and subcutaneous tissue, unspecified
2.7
6.1
30
110
ZX100
NOMESCO Finland
Oral
2.7
6.1
30
110
SFA30
NOMESCO Finland
Three-surface restoration
1.2
6.1
939
8146
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.3
6.1
45
201
JFA80
NOMESCO Finland
Suture of colon
12.5
6.1
10
8
A41.9
ICD-10 Finland
Sepsis, unspecified
2.0
6.1
59
294
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
8.6
6.1
12
14
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
835
1241
9.29
307.65
2.1
1.6
—
—
—
0
0
304
59
57.93
307.65
2.3
1.6
101.91
132.98
au/ml
—
37
9
398
78
59.67
307.65
3.0
2.0
9.60
9.36
mg/l
0.14
338
62
442
101
52.13
307.65
4.0
3.5
8.58
8.48
mg/l
0.05
374
84
2482
11262
15.85
307.65
18.1
5.9
1.84
1.98
e9/l
5.24
2395
10106
2457
7944
24.17
307.65
10.9
4.7
37.01
36.49
g/l
6.10
2424
7439
2264
10249
8.47
307.65
18.5
6.3
8.67
8.35
%
7.68
2234
9683
2260
10183
8.47
307.65
18.0
6.0
2.59
2.82
%
7.60
2230
9598
2236
9839
8.39
307.65
17.9
6.1
0.74
0.67
%
8.56
2206
9258
2266
10486
8.21
307.65
17.3
5.8
58.33
56.28
%
19.49
2234
9925
1580
4815
6.50
307.65
4.6
2.1
2.68
2.79
mg/l
1.54
1492
4129
740
1558
6.16
307.65
6.5
4.2
0.31
0.67
%
5.68
228
480
2513
12405
15.74
307.65
19.6
8.9
3.94
4.00
e9/l
0.85
2421
10911
170
10
181.35
307.65
2.9
2.5
2.91
4.29
mg/l
—
164
10
902
715
18.44
307.65
1.8
1.6
2.05
0.18
iu/ml
0.50
189
129
2454
10213
16.34
307.65
19.0
6.4
—
—
—
0
0
751
1624
6.02
307.65
7.0
4.5
0.06
0.12
%
1.72
223
481
2491
11237
16.65
307.65
18.2
6.2
0.17
0.19
e9/l
8.09
2396
10006
394
90
51.08
307.65
3.1
3.2
155.05
92.51
au/ml
0.73
48
21
2332
8482
13.80
307.65
4.4
2.2
72.88
73.76
nmol/l
0.86
2290
7803
2272
10640
8.15
307.65
18.2
6.0
28.18
29.24
%
6.25
2244
10085
2475
10873
16.25
307.65
18.0
5.9
0.04
0.04
e9/l
1.13
2370
9527
2474
10866
16.19
307.65
18.0
5.9
0.56
0.56
e9/l
0.00
2372
9532
2505
2993
102.56
307.65
8.5
2.3
206.74
114.14
ug/g
25.03
2448
2395
2626
15630
25.49
307.65
21.9
7.0
73.35
75.95
u/l
4.10
2605
14790
135
13
109.26
263.06
3.3
3.8
—
—
—
0
0
1557
7246
3.71
244.18
2.5
1.8
89.55
96.91
pmol/l
9.43
1128
3935
804
2443
4.26
236.36
2.8
2.4
21.45
24.35
%
6.39
721
2115
1839
9688
3.81
234.40
19.8
8.7
0.00
0.00
e9/l
0.56
1718
7945
2425
15617
6.41
229.71
9.0
3.8
11.90
9.89
mm/h
12.12
2357
14574
313
443
7.86
213.52
5.3
3.9
58.29
55.95
%
2.36
313
443
310
434
7.94
213.49
5.3
3.6
3.86
3.97
e9/l
0.42
310
434
811
2652
3.94
212.61
2.7
2.3
2.43
2.40
g/l
0.71
781
2464
855
2905
3.84
211.88
2.8
2.4
12.98
14.27
umol/l
4.87
837
2708
1853
10242
3.58
209.31
4.5
2.8
96.87
103.72
ug/l
0.72
1800
9625
1830
10139
3.50
203.66
7.4
6.0
10.13
11.07
umol/l
3.89
1771
9632
1342
6220
3.30
200.96
4.8
2.5
56.53
58.35
u/l
0.69
1281
5765
561
1716
3.86
157.69
4.0
2.3
0.24
0.22
g/l
2.80
543
1611
749
2885
3.21
145.54
2.0
1.7
1083.40
1181.46
nmol/l
2.15
565
2237
305
616
5.45
145.01
1.5
1.3
90.63
88.75
titre
0.03
32
64
289
577
5.49
139.02
1.2
1.3
284.94
246.84
u/ml
1.12
174
345
296
606
5.36
138.43
1.2
1.3
—
—
—
0
0
80
17
48.46
137.27
1.1
1.4
39.34
19.60
u/ml
—
26
5
255
463
5.98
135.77
3.4
6.4
263.72
800.34
iu/ml
0.96
18
65
1351
7343
2.68
135.54
4.8
3.2
30.54
31.14
u/l
0.27
1271
6984
508
1681
3.49
124.80
2.2
2.7
11.05
10.50
g/l
2.37
467
1538
231
415
5.99
124.15
1.7
1.4
—
—
—
0
0
431
1315
3.71
119.56
1.8
1.8
1.18
1.30
g/l
1.25
407
1224
1512
9148
2.48
114.55
7.5
6.5
1.21
1.21
mmol/l
0.64
1303
7835
1406
8261
2.46
113.21
6.4
5.9
1.22
1.21
mmol/l
1.65
1309
7613
226
434
5.59
112.97
1.4
1.3
—
—
—
0
0
815
3747
2.68
110.19
2.5
1.6
414.21
30573278.23
pmol/l
3.31
747
3212
74
28
27.14
108.07
1.0
1.0
—
—
—
0
0
315
838
4.12
105.68
1.6
1.8
—
—
—
0
0
158
230
7.23
103.94
1.7
1.5
—
—
—
0
0
2665
22358
15.40
102.49
30.9
11.5
14.42
21.71
mg/l
51.14
2490
17186
158
235
7.08
101.90
1.7
1.5
—
—
—
0
0
157
233
7.09
101.46
1.7
1.5
—
—
—
0
0
947
4865
2.46
99.69
1.7
1.4
2.43
2.27
g/l
2.17
698
3080
206
413
5.32
97.96
1.1
1.1
—
—
—
0
0
1335
8027
2.31
97.18
9.8
10.8
1.09
1.17
inr
5.72
473
2499
152
231
6.91
96.04
1.7
1.5
—
—
—
0
0
152
232
6.88
95.65
1.7
1.5
—
—
—
0
0
152
233
6.85
95.26
1.7
1.5
—
—
—
0
0
804
3943
2.48
92.55
1.7
1.5
21.04
20.31
nmol/l
0.43
739
3458
139
200
7.27
92.32
1.8
1.4
—
—
titre
—
0
0
115
176
6.78
72.04
1.5
1.3
126.29
201.67
titre
0.58
35
36
115
176
6.78
72.04
1.5
1.3
128.00
196.25
titre
—
5
8
110
163
6.99
71.01
1.2
1.2
—
—
—
0
0
143
275
5.43
70.97
1.3
1.2
—
—
—
0
0
109
163
6.93
69.77
1.2
1.2
—
—
—
0
0
2466
20642
3.24
69.42
22.9
10.2
92.49
90.03
ml/min/173m2
6.74
2235
16843
2663
23551
10.29
67.83
30.9
12.7
74.57
73.71
umol/l
0.77
2663
23545
277
923
3.23
65.28
1.2
1.4
—
—
—
0
0
423
1815
2.58
62.24
3.8
3.1
1.80
1.76
%
0.32
389
1642
2661
23729
9.20
62.19
27.6
9.0
26.77
27.47
u/l
1.44
2652
23031
104
167
6.44
62.18
2.6
3.6
58.54
53.60
%
1.43
85
153
109
186
6.06
61.34
1.2
1.2
60.87
60.87
u/l
0.00
97
174
254
850
3.19
59.28
1.7
1.6
5.21
9.79
u/ml
0.64
11
29
133
281
4.93
59.23
2.5
3.7
1.06
1.39
%
0.65
116
262
497
2349
2.37
59.04
3.8
2.9
6.15
7.47
umol/l
1.13
434
2033
866
5127
2.01
57.79
5.9
3.9
95.44
93.44
%
1.69
845
4997
924
5597
1.99
57.76
1.4
1.3
0.89
1.57
u/ml
2.13
232
1524
327
1299
2.73
55.88
2.6
3.0
73.88
73.04
e9/l
0.14
261
963
905
5518
1.96
54.94
4.6
3.5
0.00
0.00
estimate
1.49
449
1989
183
531
3.62
53.43
1.7
1.3
4.73
6.33
iu/ml
—
7
10
215
696
3.27
52.88
1.9
1.6
874.29
317.39
titre
1.00
14
23
149
379
4.10
52.46
1.9
1.7
0.69
0.80
g/l
0.33
117
292
1463
10531
1.85
52.16
4.1
3.2
0.00
0.00
estimate
1.06
443
1966
1450
10436
1.84
51.44
5.2
4.4
0.00
0.00
estimate
0.50
454
2044
1449
10451
1.83
50.80
4.1
3.2
0.00
0.00
estimate
1.23
453
2105
413
1976
2.29
46.89
3.3
2.5
40.94
63.32
u/l
0.44
372
1700
71
103
7.05
46.68
1.3
1.2
65.21
81.65
u/l
0.78
61
91
70
101
7.09
46.25
1.3
1.2
18.88
16.92
u/l
0.15
60
88
2320
19800
2.22
45.53
30.8
13.8
14.48
14.60
%
0.20
2315
19453
80
135
6.08
45.50
1.2
1.1
1544.18
1618.33
miu/ml
0.19
80
135
425
2088
2.23
45.15
2.0
2.1
336.87
375.60
nmol/l
4.32
396
1928
1552
11680
1.77
44.76
5.3
4.6
6.33
6.52
mmol/l
3.39
1481
10779
2486
21929
2.68
43.95
19.5
12.4
139.38
139.64
mmol/l
6.94
2438
21348
2488
22012
2.65
42.65
19.6
12.5
3.89
3.94
mmol/l
18.48
2436
21384
1736
13601
1.77
42.47
4.7
3.9
1043.67
744.21
e6/l
—
9
156
668
3978
1.90
41.52
2.8
2.5
6.00
6.71
e6/l
0.61
610
3564
1159
8161
1.74
41.02
4.3
3.2
—
—
—
0
0
120
314
3.95
40.59
1.1
1.1
1.50
1.47
g/l
0.40
113
284
993
6767
1.74
38.98
3.0
3.0
20.83
42.72
ng/l
2.40
545
3912
880
5819
1.76
38.27
3.5
3.0
27.97
76.61
e6/l
2.25
734
4394
196
724
2.84
38.10
1.6
2.0
1.45
1.44
g/l
0.08
171
638
816
5306
1.77
37.46
3.6
2.9
0.48
0.39
e6/l
0.37
669
3950
163
554
3.07
36.77
1.4
1.4
299.34
295.42
ug/g
0.07
80
305
56
82
6.95
36.50
1.5
1.4
—
—
—
0
0
55
81
6.91
35.66
1.5
1.4
—
—
—
0
0
49
68
7.32
33.51
1.6
1.5
—
—
—
0
0
49
68
7.32
33.51
1.6
1.5
—
—
—
0
0
1307
9894
1.62
32.46
3.1
2.5
—
—
—
0
0
64
121
5.39
32.32
1.7
1.6
4.62
6.12
u/l
0.42
53
102
901
6245
1.66
31.64
3.1
3.2
2.33
2.35
mmol/l
3.54
804
5629
426
2407
1.91
30.08
7.0
6.3
1.04
1.05
mmol/l
0.33
404
2249
172
672
2.67
29.94
1.3
1.1
—
—
—
0
0
51
84
6.17
29.73
1.2
1.2
—
—
—
0
0
46
69
6.76
29.33
1.2
1.2
—
—
—
0
0
731
4879
1.68
29.23
3.0
2.2
—
—
—
0
0
169
665
2.64
29.00
1.3
1.1
—
—
—
0
0
474
2802
1.84
28.98
1.8
1.8
—
—
—
0
0
364
1980
1.97
28.68
3.4
4.5
217.11
241.62
u/l
2.42
350
1887
301
1574
2.03
26.43
8.1
8.4
8.11
8.33
mmol/l
0.25
290
1518
135
502
2.78
25.86
1.3
1.5
105.97
112.92
u/ml
0.27
31
100
149
589
2.62
25.32
4.2
3.7
38.67
2451.90
u/ml
0.79
124
499
164
686
2.48
24.78
1.7
1.7
0.24
0.23
g/l
0.23
158
642
164
686
2.48
24.78
1.7
1.9
—
—
—
0
0
98
312
3.22
24.69
4.0
3.0
26.59
56.77
u/ml
0.30
98
307
66
161
4.18
24.60
2.3
1.5
—
—
—
0
0
2670
25422
5.38
24.08
40.9
16.9
40.60
40.98
%
1.17
2581
24150
484
3032
1.73
23.87
5.0
3.8
0.81
0.82
mmol/l
1.67
457
2882
194
890
2.27
23.79
1.3
1.3
0.33
1.02
u/ml
1.20
19
77
2670
25439
5.32
23.69
41.0
16.8
276.37
255.95
e9/l
46.18
2660
24880
165
709
2.41
23.51
1.7
1.7
1.18
1.18
g/l
0.02
159
663
2670
25471
5.20
22.96
40.9
16.8
4.49
4.59
e12/l
23.14
2660
24868
2670
25474
5.19
22.89
41.0
16.8
6.83
6.69
e9/l
2.34
2661
24866
555
3646
1.66
22.80
1.3
1.3
8.83
10.19
u/ml
0.21
230
1499
105
368
2.93
22.45
2.2
3.4
660.00
1812.84
u/ml
—
5
25
1858
15996
1.52
21.35
4.7
3.0
45.10
42.70
u/l
0.61
1783
15216
146
625
2.41
20.98
2.0
2.0
2.11
1.60
ug/l
0.26
134
563
59
152
3.95
20.47
1.1
1.0
—
—
—
0
0
567
3847
1.60
20.16
1.3
1.3
17.94
27.20
iu/ml
2.64
176
1200
280
1611
1.82
18.23
4.9
4.3
1.10
1.95
mmol/l
3.17
243
1346
478
3212
1.59
17.45
3.0
2.6
1.01
1.14
e6/l
0.29
297
1764
97
375
2.65
17.29
1.7
1.7
—
—
—
0
0
139
651
2.20
16.22
1.8
1.8
—
—
—
0
0
304
1874
1.70
15.51
3.5
3.0
—
—
—
0
0
262
1555
1.76
15.30
3.6
4.2
10.92
22.17
ug/l
0.67
200
1233
24
37
6.54
14.92
1.6
1.2
—
—
—
0
0
221
1266
1.81
14.54
4.1
4.1
88.29
80.74
ng/l
0.53
197
1142
144
718
2.06
14.32
2.1
1.9
—
—
—
0
0
130
624
2.14
14.28
3.5
4.9
1.44
1.37
mg/l
0.48
124
587
439
3028
1.54
14.04
3.1
2.7
3.99
2.63
e6/l
0.88
262
1589
77
298
2.63
13.75
4.0
3.9
43.83
1074.01
u/ml
0.68
72
280
111
508
2.24
13.74
2.4
2.9
—
—
—
0
0
259
1580
1.71
13.69
6.8
7.8
1.25
1.36
mmol/l
1.16
248
1537
610
4536
1.45
13.38
4.3
3.4
1.02
1.02
kg/l
0.42
108
614
239
1441
1.72
13.18
1.4
1.4
—
—
—
0
0
199
1149
1.79
12.75
3.4
3.5
4.96
5.15
kpa
3.38
190
1103
295
1915
1.61
12.21
1.6
1.7
—
—
—
0
0
70
276
2.58
12.08
1.5
1.2
—
—
—
0
0
700
5444
1.39
11.66
2.0
2.2
131.18
242.18
u/l
3.49
676
5174
295
1941
1.58
11.53
1.7
1.7
—
—
—
0
0
236
1470
1.66
11.51
3.7
3.6
1.23
1.23
mmol/l
0.00
207
1280
187
1103
1.75
11.15
3.4
3.5
1.23
1.47
mmol/l
0.37
134
811
166
953
1.79
10.86
1.5
1.6
—
—
—
0
0
625
4828
1.38
10.72
1.8
1.8
0.97
0.99
mg/l
0.10
431
3540
111
568
2.00
10.35
1.8
1.7
—
—
—
0
0
242
1569
1.60
10.05
3.2
2.4
73.11
73.84
ml/min/173m2
0.09
95
576
1887
17177
1.33
9.97
4.0
3.9
14.74
14.56
pmol/l
2.72
1733
15889
129
705
1.87
9.91
1.1
1.1
10.72
3.46
u/ml
0.41
16
107
136
757
1.84
9.87
3.8
3.6
24.61
24.70
mmol/l
0.14
131
713
721
5766
1.34
9.78
1.9
1.6
—
—
—
0
0
2175
20258
1.38
9.64
4.6
4.5
1.73
2.03
mu/l
1.92
2024
18988
29
78
3.75
9.59
2.0
3.7
—
—
—
0
0
75
344
2.21
9.33
1.2
1.1
—
—
—
0
0
201
1279
1.62
9.02
1.9
2.5
65.80
67.12
g/l
1.57
182
1189
92
464
2.02
8.97
1.5
1.7
—
—
—
0
0
177
1095
1.66
8.89
1.5
1.5
—
—
—
0
0
89
447
2.02
8.79
1.3
1.3
8.70
4.17
u/ml
—
9
30
641
5110
1.33
8.73
2.6
2.5
2732.34
4290.89
umol/l
0.68
586
4593
378
2794
1.41
8.24
2.2
2.3
29.81
29.70
s
0.15
370
2701
414
3125
1.38
7.97
3.0
2.9
2.43
2.43
mmol/l
0.04
354
2757
20
47
4.28
7.93
1.2
1.1
—
—
—
0
0
309
2218
1.44
7.92
6.9
5.7
—
—
—
0
0
81
409
2.01
7.91
3.6
3.3
32.80
34.02
umol/l
0.24
74
381
23
61
3.79
7.79
1.0
1.1
104.09
91.97
%
1.27
23
61
236
1612
1.51
7.77
1.3
1.3
150.09
233.72
u/ml
1.22
219
1497
1921
17764
1.28
7.64
3.5
3.5
—
—
—
0
0
87
460
1.92
7.47
1.6
1.7
—
—
—
0
0
87
462
1.91
7.38
2.9
2.3
9.98
5.50
umol/l
1.72
66
337
522
4130
1.33
7.36
2.4
3.0
870.63
1008.98
ng/l
0.41
431
3427
31
104
3.00
7.35
1.1
1.1
193.66
223.57
iu/ml
0.26
31
104
34
121
2.83
7.27
1.2
1.2
—
—
—
0
0
24
69
3.50
7.26
1.2
1.2
—
—
—
0
0
43
174
2.50
7.17
1.1
1.2
—
—
—
0
0
440
3412
1.35
7.09
3.4
3.3
407.85
519.37
ng/l
0.15
268
2277
217
1493
1.49
6.91
2.3
2.3
7985.84
5837.35
u/l
0.36
64
581
40
163
2.48
6.60
1.4
1.3
191556.56
77852.38
e6/l
0.29
27
113
124
764
1.65
6.40
3.3
3.3
0.70
0.66
%
0.36
124
758
17
31
5.51
6.29
5.1
7.6
32.82
44.63
ug/min
0.37
11
25
125
785
1.62
6.00
3.3
3.3
1.38
1.36
%
0.09
125
778
25
84
2.99
5.95
1.4
1.2
105.26
107.56
%
0.15
19
71
64
331
1.96
5.93
1.5
1.9
—
—
—
0
0
85
482
1.79
5.93
1.4
1.4
—
—
—
0
0
78
431
1.83
5.92
2.0
1.7
8485.74
10980.11
e6/l
0.55
65
317
43
191
2.27
5.90
2.8
2.0
36.91
20.28
mg/l
0.74
11
51
96
573
1.70
5.62
1.4
1.3
2.25
3.28
u/ml
—
10
55
22
71
3.12
5.61
1.3
1.4
10.72
8.44
ug/l
1.23
22
71
97
581
1.69
5.61
1.4
1.3
5.57
7.88
u/ml
0.29
21
92
25
89
2.83
5.40
1.5
1.2
0.31
0.29
g/l
0.47
19
72
47
226
2.10
5.34
1.0
1.1
—
—
—
0
0
37
162
2.30
5.28
1.5
1.5
33.87
33.54
%
0.01
23
105
24
85
2.84
5.24
1.2
1.3
—
1314.00
—
0
5
13
22
5.93
5.21
1.1
1.1
—
—
—
0
0
198
1416
1.43
5.21
1.0
1.0
—
—
—
0
0
44
213
2.08
4.94
1.2
1.8
—
—
—
0
0
252
1899
1.36
4.88
9.6
8.3
4.98
5.11
kpa
1.77
242
1815
52
269
1.95
4.88
1.3
1.7
—
—
—
0
0
43
208
2.08
4.85
1.3
1.6
53.04
57.29
%
0.27
26
138
70
400
1.77
4.83
1.0
1.0
1.92
2.12
u/ml
0.13
20
197
60
327
1.85
4.82
1.8
1.7
—
—
—
0
0
60
327
1.85
4.82
1.7
1.7
—
—
—
0
0
33
144
2.31
4.77
1.2
1.7
—
—
—
0
0
99
624
1.61
4.75
1.4
1.3
35.85
36.18
u/ml
—
6
33
251
1899
1.35
4.74
9.6
8.3
12.31
12.90
kpa
1.21
241
1819
71
410
1.75
4.73
1.9
3.2
1.13
1.53
ratio
—
6
37
185
1332
1.42
4.71
2.2
2.2
5.70
7.23
ug/l
0.47
158
1201
61
337
1.83
4.71
1.4
1.6
—
—
—
0
0
18
58
3.12
4.63
1.1
1.2
—
—
—
0
0
250
1901
1.35
4.58
9.7
8.3
0.50
1.04
mmol/l
1.17
195
1493
215
1598
1.38
4.55
10.8
9.0
120.73
124.02
g/l
1.36
209
1552
96
609
1.60
4.51
1.8
2.3
130.75
365.30
ug/l
2.22
82
564
71
418
1.72
4.44
2.0
3.3
34.48
38.69
mg/l
0.22
57
335
71
418
1.72
4.44
2.0
3.3
47.87
71.16
mg/l
0.64
57
334
65
1086
0.59
4.37
1.3
1.7
4.02
4.55
mg/l
0.27
47
762
42
210
2.02
4.37
1.9
1.7
—
—
—
0
0
54
297
1.83
4.26
1.3
1.5
—
—
—
0
0
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
80
498
1.62
4.09
3.5
3.7
0.33
0.35
u/ml
0.20
35
275
49
265
1.86
4.09
1.3
1.2
—
—
—
0
0
222
1691
1.34
4.04
10.5
8.8
96.36
95.91
%
0.70
216
1629
144
1025
1.43
3.95
9.6
7.6
24.39
24.48
mmol/l
0.10
137
969
83
528
1.59
3.90
1.8
1.6
1394.20
1394.42
e6/l
0.00
65
424
504
4274
1.22
3.84
2.2
2.1
—
—
—
0
0
24
102
2.37
3.74
1.2
1.2
—
—
—
0
0
82
528
1.57
3.68
1.7
1.5
18.05
34.92
e6/l
0.54
59
406
43
233
1.86
3.60
1.4
1.5
—
—
—
0
0
43
233
1.86
3.60
1.4
1.5
—
—
—
0
0
58
344
1.70
3.60
1.3
1.5
—
—
—
0
0
41
219
1.89
3.59
1.6
1.8
—
—
—
0
0
549
4728
1.20
3.55
2.3
2.2
—
—
—
0
0
194
1479
1.34
3.54
1.3
1.3
51.46
54.87
au/ml
—
7
81
132
947
1.41
3.50
1.5
2.1
37.23
39.56
u/l
0.75
118
866
207
1596
1.32
3.50
2.5
2.3
18.98
24.24
au/ml
0.34
14
145
70
440
1.61
3.49
3.2
3.2
9.03
8.69
kpa
0.87
70
430
25
112
2.24
3.48
1.2
1.3
38.60
66.73
%
—
5
15
45
251
1.81
3.45
1.2
1.5
—
—
—
0
0
17
64
2.67
3.39
1.2
1.1
—
—
—
0
0
11
28
3.94
3.28
1.0
1.2
—
—
—
0
0
31
157
1.99
3.19
3.7
2.7
—
—
—
0
0
32
164
1.96
3.19
2.2
1.8
—
—
—
0
0
32
164
1.96
3.19
2.2
1.8
—
—
—
0
0
32
164
1.96
3.19
2.2
1.8
—
—
—
0
0
25
117
2.15
3.16
1.2
1.1
—
—
—
0
0
20
85
2.36
3.15
1.6
5.8
7413.00
71.59
mg/l
0.47
14
64
146
1088
1.36
3.12
10.3
10.2
94.27
93.84
%
0.50
146
1082
97
675
1.45
3.07
2.6
2.9
198.47
175.19
%
1.48
92
647
276
2259
1.25
2.94
3.5
3.8
33.72
31.35
%
2.83
213
1654
58
369
1.58
2.81
2.4
2.6
16.53
16.78
%
0.17
29
185
35
196
1.80
2.72
1.7
1.9
—
—
—
0
0
30
160
1.88
2.71
1.5
2.2
—
—
—
0
0
63
413
1.54
2.70
1.4
1.4
21.00
20.21
u/l
0.08
53
353
44
264
1.68
2.70
1.3
1.6
—
—
—
0
0
10
29
3.46
2.69
1.6
1.9
—
—
—
0
0
46
280
1.65
2.67
1.1
1.1
—
—
—
0
0
46
280
1.65
2.67
1.4
1.4
0.17
0.39
nmol/l
—
6
17
85
595
1.44
2.66
1.5
2.2
10.91
10.61
mg/l
0.13
78
557
84
588
1.44
2.63
4.2
4.2
1.27
1.39
mmol/l
0.59
84
579
76
522
1.47
2.62
1.8
2.1
9.76
10.21
g/l
0.48
68
480
56
360
1.57
2.62
1.7
1.6
—
—
—
0
0
15
62
2.43
2.54
1.1
1.1
—
—
—
0
0
15
62
2.43
2.54
1.2
1.1
—
—
—
0
0
15
62
2.43
2.54
1.1
1.1
—
—
—
0
0
8
211
0.38
2.53
9.4
14.2
581.38
826.01
nmol/l
—
8
205
33
186
1.78
2.53
1.2
1.1
—
—
—
0
0
81
568
1.44
2.52
1.7
2.0
—
—
—
0
0
81
568
1.44
2.52
1.7
2.0
6.97
7.25
g/l
0.85
73
527
81
568
1.44
2.52
1.7
2.0
3.72
3.60
g/l
0.39
73
527
11
38
2.90
2.41
1.0
1.2
—
—
—
0
0
45
281
1.61
2.40
1.4
1.4
0.65
0.59
nmol/l
0.58
45
270
29
160
1.82
2.39
2.8
2.5
—
—
—
0
0
65
445
1.47
2.32
1.8
2.1
36.55
38.26
g/l
1.01
56
404
15
65
2.31
2.31
1.2
1.1
—
—
—
0
0
70
487
1.45
2.30
1.8
2.3
0.16
0.80
g/l
3.27
59
442
76
538
1.42
2.28
1.8
2.1
3.08
2.91
g/l
0.77
68
497
121
925
1.32
2.27
14.2
11.1
—
—
—
0
0
2130
21897
0.87
2.24
3.9
4.2
2.67
2.85
mmol/l
18.95
2009
20646
18
86
2.10
2.22
1.2
1.1
41.33
401.70
ng/l
—
6
17
138
1083
1.29
2.15
10.6
10.2
0.83
0.68
%
1.02
138
1078
9
30
3.01
2.14
1.0
1.2
—
—
—
0
0
28
159
1.77
2.13
1.2
1.2
1.05
1.05
ratio
0.02
12
63
13
55
2.37
2.12
1.4
2.0
—
—
—
0
0
14
62
2.26
2.07
1.9
2.5
62.43
89.33
ug/l
0.54
14
62
5
10
5.01
2.07
1.0
1.1
—
—
—
0
0
149
1188
1.27
2.06
2.2
2.8
148.39
152.65
ng/l
0.05
131
1057
99
747
1.34
2.06
1.3
1.3
—
—
—
0
0
25
139
1.81
2.05
1.1
1.8
—
—
—
0
0
6
15
4.01
2.04
1.0
1.3
—
—
—
0
0
59
408
1.46
2.03
1.8
2.2
0.00
0.00
g/l
-0.00
52
383
10
38
2.64
2.00
1.5
1.9
—
—
—
0
0
137
1088
1.27
1.97
10.6
10.0
1.32
1.38
%
0.34
137
1083
21
112
1.88
1.96
2.5
1.8
—
—
—
0
0
17
84
2.03
1.95
1.2
1.2
—
—
—
0
0
17
84
2.03
1.95
2.5
3.8
—
—
—
0
0
62
437
1.43
1.95
1.8
2.1
0.01
0.01
g/l
0.04
55
412
228
2694
0.83
1.93
1.3
1.6
—
—
—
0
0
16
78
2.06
1.90
1.1
1.3
91.60
93.67
%
—
5
39
58
406
1.44
1.90
1.8
2.2
0.00
0.00
g/l
-0.00
52
382
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
23
128
1.80
1.89
1.2
1.1
—
—
—
0
0
2101
21561
0.88
1.89
3.7
3.8
1.40
1.44
mmol/l
5.07
1982
20353
34
212
1.61
1.88
1.0
1.1
232.45
259.81
mg/l
0.45
29
179
94
717
1.32
1.84
1.1
1.1
—
—
—
0
0
34
214
1.60
1.82
1.0
1.1
—
—
—
0
0
15
288
0.52
1.81
2.7
3.9
52.93
29.72
u/ml
0.41
15
282
57
402
1.43
1.81
2.2
2.3
132.45
131.81
g/l
0.07
38
294
7
23
3.05
1.80
1.0
1.2
—
—
—
0
0
34
215
1.59
1.79
1.4
1.2
—
—
—
0
0
2021
20768
0.89
1.78
3.5
3.5
1.42
1.30
mmol/l
8.12
1894
19530
66
480
1.38
1.77
1.2
1.2
—
—
—
0
0
26
154
1.70
1.76
1.1
1.1
—
—
—
0
0
43
290
1.49
1.72
3.5
2.9
7.23
7.24
mmol/l
0.01
43
281
176
1463
1.22
1.72
3.1
3.4
4.68
4.59
pmol/l
0.34
157
1309
16
82
1.96
1.69
1.1
1.1
96.80
93.27
%
—
5
41
20
111
1.81
1.68
1.3
1.5
139.52
139.44
nmol/l
0.00
20
111
122
977
1.26
1.68
1.4
1.5
7.00
8.22
u/l
0.77
102
806
10
40
2.51
1.66
1.3
1.1
—
—
—
0
0
10
43
2.33
1.58
1.3
1.1
—
—
—
0
0
34
223
1.53
1.57
1.1
1.2
34.66
41.12
mg/l
0.60
28
179
38
256
1.49
1.55
1.1
1.1
—
—
—
0
0
34
224
1.52
1.54
3.9
4.7
50.29
84.94
u/ml
0.37
12
64
5
15
3.34
1.52
1.8
3.5
—
—
—
0
0
7
27
2.60
1.51
1.1
1.0
—
—
—
0
0
45
316
1.43
1.50
3.4
2.8
1.41
1.49
mmol/l
0.31
45
303
11
51
2.16
1.50
1.0
1.1
—
—
—
0
0
75
971
0.77
1.50
1.5
1.6
—
—
—
0
0
14
72
1.95
1.48
2.7
2.4
—
—
—
0
0
127
1042
1.23
1.45
2.0
1.8
—
—
—
0
0
463
4208
1.12
1.45
1.7
1.5
—
—
—
0
0
5
16
3.13
1.44
1.6
1.5
419.00
322.19
umol/24h
—
5
16
13
66
1.97
1.43
1.1
1.7
—
—
—
0
0
17
95
1.79
1.43
2.6
2.1
—
—
—
0
0
17
95
1.79
1.43
2.6
2.1
—
—
—
0
0
9
40
2.25
1.40
1.0
1.1
—
—
—
0
0
20
119
1.69
1.37
2.2
2.9
959.00
1034.64
u/ml
0.10
20
119
5
122
0.41
1.37
3.2
2.3
131.00
153.63
nmol/l
—
5
106
171
1999
0.85
1.34
1.4
1.5
—
—
—
0
0
130
1086
1.21
1.27
1.4
1.3
196.33
225.59
miu/ml
0.34
46
527
6
25
2.40
1.24
6.7
6.0
3.47
6.61
mmol/l
—
6
25
50
372
1.35
1.24
1.4
1.3
—
—
—
0
0
50
372
1.35
1.24
1.4
1.3
—
—
—
0
0
23
147
1.57
1.23
2.8
2.6
753.50
619.85
ml
0.86
18
99
5
19
2.63
1.21
1.2
1.2
—
—
—
0
0
111
921
1.21
1.18
1.4
1.5
—
—
—
0
0
17
102
1.67
1.16
1.1
1.2
—
—
—
0
0
31
215
1.45
1.15
1.3
1.6
275.88
283.25
mosm/kgh2o
1.19
24
167
2127
21665
0.91
1.13
3.7
3.9
4.54
4.73
mmol/l
16.65
2008
20545
76
610
1.25
1.11
1.1
1.1
3.88
1.22
u/ml
0.43
29
270
5
21
2.38
1.09
2.4
2.3
—
—
—
0
0
19
120
1.59
1.08
1.1
1.6
—
—
—
0
0
17
105
1.62
1.06
1.8
1.4
123.24
165.40
mmol/24h
2.13
17
105
17
105
1.62
1.06
1.1
1.7
—
—
—
0
0
17
105
1.62
1.06
1.1
1.7
—
—
—
0
0
18
114
1.58
1.02
1.7
2.4
21.19
300.79
ug/l
0.68
18
100
34
462
0.73
1.02
1.1
1.2
—
—
—
0
0
10
53
1.89
1.01
1.2
1.2
—
—
—
0
0
11
188
0.58
0.99
1.2
1.6
—
—
—
0
0
37
492
0.75
0.97
1.4
1.3
2.43
4.10
ug/l
2.02
37
455
62
496
1.26
0.96
1.4
1.2
24.90
41.64
u/ml
0.58
11
48
7
37
1.89
0.94
1.3
1.3
—
—
—
0
0
16
101
1.59
0.93
2.1
1.9
—
—
—
0
0
6
120
0.50
0.93
2.0
2.5
46.17
49.87
umol/l
—
6
105
11
63
1.75
0.90
1.2
1.1
—
—
—
0
0
6
29
2.07
0.89
1.8
1.5
—
—
—
0
0
77
638
1.21
0.89
1.1
1.1
6.54
6.56
u/ml
0.00
34
354
34
255
1.34
0.86
1.1
1.1
—
—
—
0
0
24
170
1.42
0.85
1.4
1.8
—
—
—
0
0
51
407
1.26
0.83
1.1
1.1
—
—
—
0
0
16
237
0.67
0.81
1.4
1.4
148.12
178.52
pmol/l
0.75
16
237
378
3523
1.08
0.76
1.8
1.8
1.40
1.43
%
0.45
320
3160
106
919
1.16
0.76
1.6
1.5
—
—
—
0
0
81
687
1.18
0.76
1.1
1.1
0.76
2.50
u/ml
2.07
33
354
159
1420
1.13
0.75
1.4
1.4
20.68
22.51
iu/l
0.36
137
1194
623
5927
1.07
0.73
3.3
3.4
8.10
8.21
mmol/l
0.22
547
5157
15
100
1.50
0.72
1.3
3.5
89.30
133.55
umol/l
—
10
53
10
60
1.67
0.72
3.2
4.7
—
—
—
0
0
89
1030
0.86
0.71
1.4
1.4
—
—
—
0
0
20
274
0.73
0.69
1.6
1.5
—
—
—
0
0
5
27
1.85
0.68
2.4
2.0
—
—
—
0
0
90
1035
0.87
0.67
1.4
1.4
—
—
—
0
0
90
1034
0.87
0.66
1.4
1.4
—
—
—
0
0
5
28
1.79
0.66
1.6
2.3
—
—
—
0
0
90
1033
0.87
0.66
1.4
1.4
—
—
—
0
0
24
180
1.34
0.65
1.2
1.3
0.02
1.11
u/ml
2.93
11
91
99
1126
0.87
0.64
1.4
1.5
—
—
—
0
0
520
4943
1.06
0.63
3.3
3.4
400.81
301.98
mg/l
0.20
365
3241
115
1293
0.88
0.63
1.5
1.4
—
—
—
0
0
18
245
0.73
0.61
1.8
2.3
21.63
21.65
nmol/l
0.00
18
233
197
1807
1.10
0.60
1.2
1.2
100.85
148.58
iu/ml
0.80
55
682
0
20
0.00
0.60
0.0
1.1
—
0.23
—
0
15
22
165
1.34
0.60
2.6
2.8
37804.55
40121.72
ug/l
0.52
22
165
8
52
1.54
0.59
1.0
1.1
—
—
—
0
0
8
54
1.48
0.57
1.3
1.5
—
—
—
0
0
118
1058
1.12
0.56
2.1
2.8
65.10
44.30
u/ml
0.42
111
1022
5
87
0.57
0.56
1.0
1.0
—
—
—
0
0
20
150
1.34
0.55
1.3
1.2
—
—
—
0
0
541
5172
1.06
0.55
4.0
4.0
12.90
9.35
mg/mmol
0.68
372
3364
47
394
1.20
0.55
1.5
1.3
3.29
4.82
u/ml
0.82
24
176
541
5176
1.06
0.54
4.0
4.1
1.77
2.00
ug/l
1.14
501
4704
24
187
1.29
0.52
1.2
1.1
—
—
—
0
0
24
187
1.29
0.52
1.2
1.1
—
—
—
0
0
24
187
1.29
0.52
1.2
1.1
—
—
—
0
0
24
187
1.29
0.52
1.2
1.1
—
—
—
0
0
24
188
1.28
0.51
1.2
1.1
—
—
—
0
0
11
156
0.70
0.49
1.0
1.3
1.43
1.56
g/l
1.28
11
156
68
772
0.88
0.47
1.4
1.5
—
—
—
0
0
7
50
1.40
0.45
4.1
6.1
—
—
—
0
0
17
217
0.78
0.41
2.1
3.1
—
—
—
0
0
36
423
0.85
0.41
4.3
3.2
23.59
22.68
mg/l
0.05
15
261
0
18
0.00
0.40
0.0
1.2
—
20.76
—
0
9
117
1272
0.92
0.40
1.5
1.6
288.15
291.50
mu/l
0.04
105
1147
18
226
0.80
0.39
1.7
1.7
—
—
—
0
0
43
495
0.87
0.38
2.1
1.7
—
—
—
0
0
81
895
0.90
0.38
1.8
1.7
—
—
—
0
0
20
160
1.25
0.38
3.0
4.2
—
—
—
0
0
5
36
1.39
0.38
1.6
2.3
1.19
1.21
mmol/l
—
5
36
67
601
1.12
0.36
1.0
1.1
2.22
1.94
u/ml
0.10
32
300
12
90
1.33
0.35
1.0
1.1
—
—
—
0
0
20
162
1.24
0.35
1.4
1.4
76.60
75.46
umol/l
0.13
20
162
20
162
1.24
0.35
1.2
1.1
0.95
1.04
u/l
—
10
76
521
5377
0.96
0.34
1.8
1.6
1.55
1.42
mmol/l
2.00
462
4643
48
426
1.13
0.32
1.3
1.3
—
—
—
0
0
45
398
1.13
0.32
1.4
1.3
2.74
4.51
u/ml
0.50
19
136
1934
19162
1.03
0.31
4.6
4.7
37.31
38.52
mmol/mol
8.87
1814
18060
46
408
1.13
0.31
1.1
1.1
—
—
—
0
0
2071
20543
1.03
0.31
3.8
3.8
5.72
5.78
mmol/l
1.49
1921
19112
65
589
1.11
0.31
1.6
2.0
6.04
4.64
iu/l
0.35
20
226
11
84
1.31
0.30
1.1
1.5
64.82
101.23
nmol/24h
1.31
11
84
292
3037
0.96
0.29
2.5
2.7
0.57
0.69
ug/l
3.37
181
1764
48
431
1.12
0.28
1.0
1.0
0.76
0.37
u/ml
0.23
11
126
55
500
1.10
0.26
1.0
1.1
3.05
3.61
u/ml
0.15
23
238
9
75
1.20
0.25
1.6
1.7
—
—
—
0
0
10
78
1.28
0.24
3.0
2.3
—
—
—
0
0
10
78
1.28
0.24
3.0
2.3
—
—
—
0
0
10
79
1.27
0.22
3.0
2.3
—
—
—
0
0
207
2152
0.96
0.22
2.0
2.0
—
—
—
0
0
5
42
1.19
0.21
1.2
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
6.5
—
—
—
0
0
42
382
1.10
0.21
1.1
1.1
129.89
116.75
%
1.32
36
354
0
12
0.00
0.21
0.0
1.1
—
8.07
—
0
12
0
12
0.00
0.21
0.0
5.1
—
443.92
—
0
12
0
13
0.00
0.21
0.0
3.7
—
—
—
0
0
0
13
0.00
0.21
0.0
3.2
—
—
—
0
0
11
89
1.24
0.21
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
9
113
0.80
0.20
1.4
1.4
71.67
73.51
%
—
9
108
14
118
1.19
0.19
1.4
2.1
1.00
2.08
u/field
—
7
64
25
277
0.90
0.16
2.4
2.3
—
—
—
0
0
10
83
1.21
0.15
1.1
1.0
—
—
—
0
0
9
78
1.15
0.15
1.4
1.1
—
—
—
0
0
20
179
1.12
0.14
1.4
1.4
—
—
—
0
0
49
460
1.07
0.14
1.0
1.1
7.21
5.52
u/ml
0.20
18
186
9
110
0.82
0.13
1.4
1.4
504.44
390.96
mu/l
—
9
105
52
492
1.06
0.12
1.4
1.5
0.53
0.43
nmol/l
0.43
41
401
22
202
1.09
0.10
1.0
1.1
—
—
—
0
0
11
97
1.13
0.09
1.7
1.9
—
—
—
0
0
11
97
1.13
0.09
1.7
1.9
—
—
—
0
0
405
4097
0.99
0.08
3.7
3.6
20.82
20.97
%
0.07
181
1645
5
65
0.77
0.08
1.0
1.1
36.14
48.14
u/ml
—
5
65
42
438
0.96
0.07
2.8
2.5
53.57
116.63
ug/min
1.28
27
271
44
458
0.96
0.07
1.5
2.6
0.96
0.82
nmol/l
0.50
39
396
193
1902
1.02
0.06
2.1
2.2
12.75
12.93
nmol/l
0.13
178
1746
266
2691
0.99
0.06
2.1
2.0
—
—
—
0
0
15
139
1.08
0.05
1.6
1.4
3742.44
1997.63
e6/l
—
9
97
16
150
1.07
0.04
1.6
2.7
40.93
44.67
%
—
10
73
50
487
1.03
0.04
1.6
1.6
—
—
—
0
0
10
109
0.92
0.04
2.2
1.6
1.31
1.29
nmol/l
—
10
89
38
392
0.97
0.04
1.1
1.1
24.36
1244.59
iu/ml
—
7
110
110
1089
1.01
0.02
2.1
1.9
—
—
—
0
0
13
123
1.06
0.01
1.7
1.4
20617.14
27874.44
e6/l
—
7
71
13
137
0.95
0.01
2.1
1.7
—
—
—
0
0
21
205
1.02
0.00
2.2
1.6
1.33
1.36
promille
0.02
13
162
21
211
1.00
0.00
1.1
1.1
—
—
—
0
0
29
291
1.00
0.00
1.6
1.6
7.58
7.59
mmol/l
0.01
29
281
21
214
0.98
0.00
3.2
3.1
0.70
0.82
nmol/l
0.90
12
169
0
6
0.00
-0.00
0.0
1.2
—
7.85
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
2.17
—
0
6
0
6
0.00
-0.00
0.0
5.3
—
0.34
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint K11_CD_STRICT2 and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_CD_STRICT2 | 1.165 [1.01, 1.34] | 0.033 |
| Birth year | 0.998 [0.99, 1.01] | 0.711 |
During the follow-up period (1.1.1998 — 31.12.2019), 291 out of 5295 females with K11_CD_STRICT2 died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_CD_STRICT2 | 1.13 [0.99, 1.29] | 0.074 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 374 out of 5115 males with K11_CD_STRICT2 died.
Mortality risk
Mortality risk for people of age
years, who have K11_CD_STRICT2.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.11% | 0.199% |
| 5 | 0.842% | 1.372% |
| 10 | 1.983% | 3.277% |
| 15 | 3.736% | 6.183% |
| 20 | 6.677% | 10.509% |
Relationships between endpoints
↥Index endpoint: K11_CD_STRICT2 – Crohn disease (strict definition, require KELA, min 2 HDR)
GWS hits: 16
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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