No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
1 out of 7 registries used, show all original rules. |
526 |
4. Check minimum number of eventsNone |
526 |
5. Include endpointsNone |
526 |
6. Filter based on genotype QC (FinnGen only) |
512 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- C
- First used in FinnGen datafreeze
- DF5
Similar endpoints
↥List of similar endpoints to
Hypotension due to drugs
based on the number of shared cases.
Similar with more cases:
- Hypotension
- Other CVD (FINNGEN)
- Other CVD
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4146 | 2120 | 2001 |
| Only index persons | 3614 | 1853 | 1761 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.06 |
| Only index persons | 0.07 | 0.07 | 0.07 |
| Median age at first event (years) | |||
| Whole population | 77.94 | 80.37 | 75.41 |
| Only index persons | 77.93 | 80.44 | 75.30 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 512 | 206 | 306 |
| Unadjusted period prevalence (%) | 0.11 | 0.07 | 0.14 |
| Median age at first event (years) | 74.10 | 73.49 | 74.50 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 526
- Matched controls
- 5260
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I95.2
ICD-10 Finland
Hypotension due to drugs
+∞
307.7
526
8
I95.9
ICD-10 Finland
Hypotension, unspecified
10.7
44.3
50
51
C03CA01
ATC
furosemide; systemic
3.5
41.9
330
1720
R07.4
ICD-10 Finland
Chest pain, unspecified
3.4
40.9
241
1051
R55
ICD-10 Finland
Syncope and collapse
4.0
40.3
142
442
I50.9
ICD-10 Finland
Heart failure, unspecified
3.4
39.4
204
818
C01DA14
ATC
isosorbide mononitrate; oral
3.3
38.2
211
878
I25.1
ICD-10 Finland
Atherosclerotic heart disease
3.1
36.0
249
1173
T36
ICD-10 Finland
Poisoning by systemic antibiotics
8.6
35.5
47
59
R53
ICD-10 Finland
Malaise and fatigue
3.0
31.6
207
932
F32.9
ICD-10 Finland
Depressive episode, unspecified
4.4
31.4
90
238
C07AB07
ATC
bisoprolol; oral
3.1
31.1
380
2385
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.3
30.6
143
528
I95.1
ICD-10 Finland
Orthostatic hypotension
5.1
30.4
69
151
R42
ICD-10 Finland
Dizziness and giddiness
2.9
28.8
197
900
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
27.6
331
2002
E86
ICD-10 Finland
Volume depletion
6.5
27.2
46
76
AN1
HP
Coronary angiography
3.3
27.0
128
473
C03DA01
ATC
spironolactone; oral
3.2
27.0
134
509
R06.0
ICD-10 Finland
Dyspnoea
2.7
26.4
218
1089
N05AH04
ATC
quetiapine; oral
3.1
25.9
132
508
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
2.7
25.6
203
991
I50.0
ICD-10 Finland
Congestive heart failure
3.3
24.7
109
384
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.7
23.9
180
851
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.5
23.4
235
1274
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
8.8
23.3
30
36
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.6
23.2
203
1030
AA1AD
NOMESCO Finland
CT of head and brain
2.5
22.9
217
1142
I20.09
ICD-10 Finland
Unstable angina
3.7
22.4
78
235
205
Kela drug reimbursment
Chronic hypertension
2.5
22.2
238
1322
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.9
21.9
123
497
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.0
21.7
117
461
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.5
21.7
225
1229
B01AC04
ATC
clopidogrel; oral
2.6
20.5
160
762
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
20.2
103
393
N03AG01
ATC
valproic acid; systemic, rectal
4.4
19.9
52
127
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.3
19.7
234
1343
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
3.3
19.6
82
278
I10
ICD-10 Finland
Essential (primary) hypertension
2.6
19.6
406
2959
N05AX12
ATC
aripiprazole; systemic
7.6
18.8
27
37
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
3.4
18.7
74
242
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.5
18.6
155
756
SPAT1254
SPAT
Administration of medicine
2.7
18.5
126
558
I25.2
ICD-10 Finland
Old myocardial infarction
3.1
18.4
89
328
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
18.4
142
669
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.4
18.2
185
986
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.3
18.0
197
1082
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.9
17.6
55
153
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
17.4
195
1080
C08CA01
ATC
amlodipine; oral
2.2
17.0
274
1750
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.0
16.9
50
134
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
3.0
16.8
84
315
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
2.2
16.8
199
1124
K59.09
ICD-10 Finland
Constipation, unspecified
3.3
16.8
67
220
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.2
16.4
211
1230
I50.1
ICD-10 Finland
Left ventricular failure
3.3
16.2
65
214
I20.99
ICD-10 Finland
Angina pectoris, unspecified
3.0
16.0
76
277
SPAT1301
SPAT
No procedures
2.2
15.8
208
1218
B01AA03
ATC
warfarin; systemic
2.2
15.6
185
1040
ZXD05
NOMESCO Finland
Urgent procedure
2.2
15.3
191
1094
N05AA02
ATC
levomepromazine; systemic
4.3
15.2
40
98
M04AA01
ATC
allopurinol; systemic
2.4
15.1
124
595
N05AH03
ATC
olanzapine; systemic
4.1
15.1
43
112
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.4
14.8
120
572
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.4
14.8
123
593
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
14.8
191
1105
SPAT1263
SPAT
Sampling
2.1
14.6
244
1553
N05AX08
ATC
risperidone; systemic
2.8
14.6
82
327
J01DB01
ATC
cefalexin; oral
2.5
14.6
434
3440
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.6
14.5
97
423
A02BC02
ATC
pantoprazole; systemic
2.2
14.2
377
2833
C10AA01
ATC
simvastatin; oral
2.0
14.0
302
2098
C07AB02
ATC
metoprolol; systemic
2.1
13.9
167
937
N06AX11
ATC
mirtazapine; oral
2.1
13.7
198
1189
R07.3
ICD-10 Finland
Other chest pain
2.8
13.7
78
313
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.7
13.4
43
122
N02BE01
ATC
paracetamol; systemic, rectal
3.0
13.3
476
3996
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
13.1
98
449
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
12.9
126
648
N06AB10
ATC
escitalopram; oral
2.4
12.8
101
474
C09AA05
ATC
ramipril; oral
2.0
12.8
194
1180
N17.9
ICD-10 Finland
Acute renal failure, unspecified
3.5
12.8
46
141
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.9
12.7
64
240
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.4
12.6
25
48
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.3
12.6
110
539
C10AA05
ATC
atorvastatin; oral
1.9
12.5
263
1785
N30.0
ICD-10 Finland
Acute cystitis
2.4
12.5
101
478
207
Kela drug reimbursment
Chronic arrhythmias
2.2
12.4
137
738
A28
ICPC
Limited function/disability NOS
2.1
12.4
147
815
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
4.0
12.4
36
95
N05BA04
ATC
oxazepam; oral
2.1
12.4
160
916
Z02.7
ICD-10 Finland
Issue of medical certificate
3.1
12.4
53
181
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.7
12.3
71
286
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
12.3
118
602
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
12.2
120
618
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.9
12.1
59
217
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
2.6
12.1
80
345
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.1
12.1
143
791
L28
ICPC
Limited function/disability (L)
2.1
12.1
136
738
A04
ICPC
Weakness/tiredness general
2.3
12.0
105
514
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.3
12.0
99
473
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.6
11.9
40
117
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.6
11.9
73
304
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.5
11.8
81
355
A06AD11
ATC
lactulose; oral
2.1
11.8
129
691
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
11.8
156
898
H02AB06
ATC
prednisolone; systemic
1.9
11.6
273
1907
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
11.6
62
240
N03AX16
ATC
[U] pregabalin
2.1
11.5
140
780
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.0
11.5
177
1073
A02BC05
ATC
esomeprazole; systemic
1.9
11.5
223
1463
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
3.0
11.3
52
185
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
11.3
136
755
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
5.7
11.3
21
38
R11
ICD-10 Finland
Nausea and vomiting
2.7
11.2
65
263
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.7
11.1
26
58
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
11.1
106
538
K59.0
ICD-10 Finland
Constipation
2.9
11.0
54
199
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
2.5
11.0
78
347
R03AC02
ATC
salbutamol; inhalant
1.9
11.0
278
1977
R50.9
ICD-10 Finland
Fever, unspecified
2.3
10.9
96
470
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
2.4
10.9
82
375
I20.00
ICD-10 Finland
Unstable angina
3.5
10.9
39
119
M10.9
ICD-10 Finland
Gout, unspecified
2.7
10.9
63
254
H02AA02
ATC
fludrocortisone; oral
10.9
10.9
20
19
E66.8
ICD-10 Finland
Other obesity
4.2
10.8
29
72
K29
ICPC
Cardiovascular sympt/complt other
3.4
10.8
39
120
N06AX16
ATC
venlafaxine; oral
2.6
10.7
69
293
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.6
10.6
35
101
I20.90
ICD-10 Finland
Angina pectoris, unspecified
3.1
10.6
45
153
F29
ICD-10 Finland
Unspecified nonorganic psychosis
5.0
10.6
23
48
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
10.5
188
1193
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
10.5
46
159
M54.5
ICD-10 Finland
Low back pain
1.9
10.5
180
1128
N06AB03
ATC
fluoxetine; oral
2.4
10.4
75
336
I95.8
ICD-10 Finland
Other hypotension
12.4
10.4
18
15
A46
ICD-10 Finland
Erysipelas
2.2
10.4
106
551
WX892
NOMESCO Finland
Monitored bed care
2.7
10.3
59
236
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
3.2
10.3
42
139
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
10.3
106
553
SPAT1216
SPAT
Assessment of functional ability
2.1
10.3
120
657
351
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
2.1
10.2
122
673
T90
ICPC
Diabetes non-insulin dependent
1.9
10.2
153
915
N06AX26
ATC
vortioxetine; oral
3.3
10.1
38
120
C01AA05
ATC
digoxin; systemic
2.2
10.0
90
444
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
10.0
76
349
N06AA09
ATC
amitriptyline; systemic
2.5
9.9
64
272
N03AX12
ATC
[U] gabapentin; oral
2.1
9.9
101
525
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.0
9.8
44
154
M10
ICD-10 Finland
Gout
3.2
9.8
39
127
C09CA03
ATC
valsartan; oral
2.5
9.8
68
299
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
13.7
9.7
16
12
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
13.7
9.7
16
12
81
HP
Angiography of the heart and coronary arteries
2.5
9.7
67
294
R51.80
ICD-10 Finland
Headache
2.3
9.7
80
381
SPAT1053
SPAT
Memory test
2.0
9.6
122
686
N17
ICPC
Vertigo/dizziness
2.3
9.6
83
402
N05BA01
ATC
diazepam; systemic, rectal
2.2
9.6
85
416
N05AB03
ATC
perphenazine; systemic, rectal
4.2
9.6
26
65
N05AF03
ATC
chlorprothixene; systemic
4.9
9.6
21
44
R41.0
ICD-10 Finland
Disorientation, unspecified
3.5
9.6
34
103
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.1
9.6
112
612
E87.5
ICD-10 Finland
Hyperkalaemia
4.3
9.5
25
61
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
9.4
211
1426
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
2.5
9.4
61
260
XF600
NOMESCO Finland
Bloodpressure measurement
2.8
9.4
50
193
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.7
9.4
53
211
B01AF02
ATC
apixaban; oral
2.1
9.4
98
513
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
3.4
9.3
34
105
K78
ICPC
Atrial fibrillation/flutter
2.3
9.3
74
346
P76
ICPC
Depressive disorder
3.8
9.3
28
76
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
8.0
9.2
20
26
A11
ICPC
Chest pain NOS
2.5
9.2
62
269
S97
ICPC
Chronic ulcer skin
2.5
9.2
58
244
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
9.1
195
1297
F31.8
ICD-10 Finland
Other bipolar affective disorders
11.7
9.1
16
14
SPAT1240
SPAT
Therapeutic discussion
2.9
9.1
44
161
F10.24
ICD-10 Finland
Alcohol depence active use
10.3
9.1
17
17
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.8
9.1
46
173
SPAT1229
SPAT
Assessment of need for aid
2.4
9.1
64
284
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
9.0
100
535
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.1
9.0
25
64
SPAT1262
SPAT
Handing over of treatment supplies
2.0
8.9
116
657
M79.6
ICD-10 Finland
Pain in limb
1.8
8.9
210
1435
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
8.9
157
983
P15
ICPC
Chronic alcohol abuse
4.8
8.9
20
43
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
8.9
89
458
EBA10
NOMESCO Finland
Operative extraction of tooth
2.6
8.9
52
211
P03
ICPC
Feeling depressed
3.0
8.8
39
136
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
8.8
229
1609
SPAT1234
SPAT
Support of social functional capacity
2.7
8.8
47
182
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
8.7
177
1156
N02AX02
ATC
tramadol; systemic, rectal
1.7
8.7
242
1731
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.4
8.6
60
264
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
8.6
170
1100
P29
ICPC
Psychological sympt/compl other
3.4
8.6
31
95
SPAT1307
SPAT
Psychosocial counselling and guidance
4.3
8.5
22
53
SPAT1312
SPAT
General health counselling
1.8
8.5
160
1020
N03AX09
ATC
lamotrigine; oral
3.9
8.4
25
67
J01MA12
ATC
levofloxacin; systemic
1.9
8.4
125
739
N02AA05
ATC
oxycodone; systemic
1.9
8.4
131
787
I42.0
ICD-10 Finland
Dilated cardiomyopathy
3.5
8.3
29
87
C07AA07
ATC
sotalol; systemic
2.8
8.3
42
158
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
2.5
8.2
52
219
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
8.2
63
290
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.3
8.2
62
284
G47.3
ICD-10 Finland
Sleep apnoea
1.9
8.2
120
707
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
7.0
8.1
19
28
L17
ICPC
Foot/toe symptom/complaint
1.8
8.1
151
959
A10BK01
ATC
dapagliflozin; oral
2.6
8.1
46
184
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.4
8.1
57
253
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
8.0
203
1405
B81
ICPC
Anaemia vit B12/folate deficiency
3.0
8.0
35
121
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
8.0
81
418
N05BA06
ATC
lorazepam; systemic, sublingual
2.7
8.0
44
173
N05CF01
ATC
zopiclone; oral
1.7
8.0
193
1320
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.0
7.8
34
117
NF1AA
NOMESCO Finland
Hip X-ray examination
2.2
7.8
67
323
N18.8
ICD-10 Finland
Other chronic renal failure
3.8
7.8
24
66
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
3.3
7.8
30
96
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.4
7.8
55
244
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
3.1
7.8
32
107
N06AX21
ATC
duloxetine; oral
2.3
7.7
58
264
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
7.7
244
1788
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
2.8
7.7
40
152
E66.01
ICD-10 Finland
Obesity due to excess calories
2.8
7.7
40
152
R02
ICPC
Shortness of breath/dyspnoea
2.1
7.7
81
423
XF402
NOMESCO Finland
ECG with work load test
2.1
7.7
74
374
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
4.1
7.7
21
53
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
2.9
7.6
36
130
I25
ICD-10 Finland
Chronic ischaemic heart disease
2.6
7.6
44
177
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.1
7.6
82
433
I48.2
ICD-10 Finland
Chronic atrial fibrillation
2.6
7.5
43
172
N05BA12
ATC
alprazolam; oral
2.3
7.5
59
274
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.9
7.5
102
584
C07AG02
ATC
carvedilol; oral
2.4
7.5
52
229
F20.9
ICD-10 Finland
Schizophrenia, unspecified
6.1
7.4
19
32
E66.00
ICD-10 Finland
Metabolic syndrome
2.9
7.4
34
121
H02AB07
ATC
prednisone; oral
2.0
7.4
86
467
A12BA01
ATC
potassium chloride; oral
2.5
7.4
48
205
82
HP
Single vessel balloon catheter extension
3.3
7.3
27
84
PD5AD
NOMESCO Finland
CT of aorta
3.9
7.3
21
55
AN4
HP
Balloon angioplasty and drug eluding stent
3.1
7.3
30
100
J01CA04
ATC
amoxicillin; systemic
1.8
7.3
388
3240
A10AE04
ATC
insulin glargine; parenteral
2.1
7.3
69
346
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
6.4
7.3
18
29
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
3.8
7.3
22
60
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
7.3
69
347
UJF32
NOMESCO Finland
Coloscopy
1.7
7.2
153
1003
N06AB04
ATC
citalopram; systemic
1.8
7.2
114
685
R39.1
ICD-10 Finland
Other difficulties with micturition
3.3
7.2
27
85
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.6
7.2
43
176
A10AB05
ATC
insulin aspart; parenteral
2.3
7.2
54
246
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.1
7.2
75
391
F03
ICD-10 Finland
Unspecified dementia
2.5
7.1
46
196
Z3231
NOMESCO Finland
Registered nurse
1.7
7.1
154
1016
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.3
7.1
26
81
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
7.1
7.0
16
23
N05AH02
ATC
clozapine; systemic
7.1
7.0
16
23
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
7.0
42
172
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
7.0
116
706
P20
ICPC
Memory disturbance
1.9
7.0
108
643
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
2.5
7.0
45
191
A10BH01
ATC
sitagliptin; oral
2.1
7.0
67
338
A08
ICPC
Swelling
2.6
6.9
41
167
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
7.7
6.9
15
20
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.3
6.9
26
82
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
2.5
6.9
45
192
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
6.9
96
554
A13
ICPC
Concern/fear medical treatment
4.2
6.9
18
44
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.4
6.8
46
200
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.6
6.8
22
63
TPH07
NOMESCO Finland
Cathetrisation of artery
2.0
6.7
75
400
M10.0
ICD-10 Finland
Idiopathic gout
2.9
6.7
31
111
E87.6
ICD-10 Finland
Hypokalaemia
3.1
6.6
28
95
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.5
6.6
41
171
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.7
6.6
34
129
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.3
6.6
17
41
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.3
6.6
17
41
M54.4
ICD-10 Finland
Lumbago with sciatica
2.0
6.6
80
440
ZXE00
NOMESCO Finland
One hour or less
1.6
6.6
198
1419
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
10.2
6.6
12
12
S06.0
ICD-10 Finland
Concussion
2.1
6.6
65
332
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
2.1
6.6
62
311
G44.2
ICD-10 Finland
Tension-type headache
2.1
6.6
63
318
A10BA02
ATC
metformin; oral
1.7
6.6
173
1199
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
6.5
40
166
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.5
6.5
40
166
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.0
6.5
28
96
D10
ICPC
Vomiting
3.2
6.5
25
80
S20.2
ICD-10 Finland
Contusion of thorax
2.7
6.5
35
136
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.6
6.5
36
142
K30
ICD-10 Finland
Functional dyspepsia
2.2
6.5
56
271
C03AA03
ATC
hydrochlorothiazide; oral
2.1
6.5
68
355
I50
ICD-10 Finland
Heart failure
2.7
6.4
33
125
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
3.0
6.4
28
97
M02AA07
ATC
piroxicam; topical
1.6
6.4
198
1426
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
6.4
69
364
AN3
HP
Balloon angioplasty and metallic stent
3.0
6.4
27
92
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
6.4
157
1068
WZC00
NOMESCO Finland
Treatment plan or consultation
1.7
6.3
165
1138
C02AC05
ATC
moxonidine; oral
2.6
6.3
36
144
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
6.3
82
461
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
6.3
87
499
IGY99
NOMESCO Finland
Other psychiatric treatment contact
9.4
6.3
12
13
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.1
6.3
64
330
I84.0
ICD-10 Finland
Internal thrombosed hemorrhoids
18.3
6.3
9
5
B01AB05
ATC
enoxaparin; parenteral
1.6
6.2
177
1247
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
6.2
232
1746
K07
ICPC
Swollen ankles/oedema
2.5
6.2
38
158
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
2.7
6.2
32
122
N30.9
ICD-10 Finland
Cystitis, unspecified
2.4
6.2
41
177
R00.1
ICD-10 Finland
Bradycardia, unspecified
2.7
6.2
33
128
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
2.6
6.2
36
146
C10AA03
ATC
pravastatin; oral
2.2
6.2
53
256
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.4
6.1
43
190
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.0
6.1
64
333
K08.3
ICD-10 Finland
Retained dental root
2.3
6.1
46
210
R03BB04
ATC
tiotropium bromide; inhalant
1.9
6.1
77
429
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
3.3
6.1
22
68
N04AA02
ATC
biperiden; systemic
5.3
6.1
17
33
L03
ICPC
Low back symptom/complaint
1.7
6.0
130
851
AN2
HP
Balloon angioplasty, including several vessels
3.1
6.0
25
84
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
268
1322
3.09
35.65
3.2
2.1
187.79
291.08
u/l
0.82
256
1235
296
1556
3.06
34.92
4.9
3.3
2728.51
1781.47
ng/l
1.45
267
1353
364
2227
3.06
31.24
6.9
6.2
12.49
12.21
umol/l
0.15
349
2107
240
1185
2.89
30.74
2.7
2.2
3.01
3.24
mg/l
0.72
206
1007
365
2276
2.97
29.49
29.7
19.0
1.44
1.35
inr
0.86
106
658
312
1843
2.70
27.10
8.2
4.2
44.31
59.28
ng/l
0.34
258
1431
321
1935
2.69
26.56
5.7
4.7
33.79
34.59
g/l
1.69
294
1792
178
818
2.78
25.22
2.5
1.9
—
—
—
0
0
287
1676
2.57
24.77
3.3
2.7
142.39
152.06
ug/l
0.32
263
1517
378
2540
2.74
23.99
9.4
4.8
7.03
6.84
mmol/l
0.92
368
2399
137
569
2.90
23.28
2.5
1.8
—
—
—
0
0
157
701
2.77
23.26
3.6
3.2
0.79
0.82
mmol/l
1.31
141
656
115
437
3.09
22.87
3.7
2.8
8.75
7.19
ug/l
0.26
96
383
138
583
2.85
22.65
5.9
5.2
1.05
1.03
mmol/l
0.28
128
533
161
738
2.70
22.57
2.8
2.4
12.17
12.10
umol/l
0.03
150
684
241
1346
2.46
22.22
3.4
2.5
55.00
118.91
u/l
0.55
224
1255
107
400
3.10
21.82
8.1
6.9
11.02
11.19
mmol/l
0.08
100
377
134
573
2.80
21.38
2.6
1.9
—
—
—
0
0
182
910
2.53
21.14
7.7
4.1
298.28
251.36
ng/l
0.11
163
772
333
2184
2.43
20.95
10.8
6.6
1.20
1.21
mmol/l
1.00
287
1840
148
676
2.66
20.67
2.9
2.4
2.28
2.28
g/l
0.00
135
620
389
2768
2.56
19.94
7.3
5.1
12.20
4037.71
e6/l
—
5
58
140
644
2.60
19.11
2.8
2.4
21.34
21.69
%
0.09
116
557
127
561
2.67
18.79
8.9
6.6
5.23
5.08
kpa
0.73
121
541
307
2002
2.28
18.73
10.4
5.8
1.20
1.21
mmol/l
1.30
282
1818
127
562
2.66
18.71
9.0
6.6
11.27
11.51
kpa
0.17
121
542
422
3163
2.69
18.66
10.4
7.6
86.15
80.39
u/l
1.21
393
2950
290
1849
2.27
18.66
2.5
2.1
93.01
92.80
pmol/l
0.02
167
982
186
990
2.36
18.37
1.8
1.8
1118.68
1196.58
nmol/l
0.52
142
738
219
1250
2.29
18.36
3.8
3.3
45.55
34.89
u/l
0.51
208
1190
81
288
3.14
17.82
1.8
1.5
—
—
—
0
0
124
559
2.59
17.49
9.0
6.6
1.19
1.30
mmol/l
0.11
102
445
107
448
2.74
17.49
4.6
3.2
263.65
261.22
ng/l
0.02
95
413
259
1641
2.14
16.17
5.0
3.4
—
—
—
0
0
229
1396
2.13
15.69
4.9
3.6
29.36
118.58
e6/l
1.21
190
1090
324
2274
2.11
15.00
13.4
8.9
4.43
4.34
e9/l
0.29
293
2001
200
1174
2.14
14.96
1.8
1.6
18.45
20.54
nmol/l
1.06
176
1000
104
462
2.56
14.95
5.4
3.5
2.46
1.96
mmol/l
0.72
86
370
277
1843
2.06
14.73
7.9
5.5
58.90
58.69
%
0.10
256
1727
145
770
2.22
13.82
4.2
3.1
1.12
1.18
e6/l
0.08
93
453
175
1009
2.10
13.46
5.8
3.9
81.89
84.03
%
0.46
168
989
101
464
2.46
13.43
5.6
3.5
6.01
5.79
kpa
1.32
95
447
155
857
2.15
13.27
1.9
1.7
1.28
1.47
mg/l
0.34
125
690
207
1279
2.02
13.11
4.9
3.4
0.60
0.61
e6/l
0.01
171
983
275
1880
1.97
12.98
8.2
5.7
25.18
25.79
%
0.34
253
1754
229
1472
1.98
12.91
2.9
3.3
2.33
2.34
mmol/l
0.50
198
1287
137
730
2.19
12.83
4.3
3.3
2.45
1.99
e6/l
0.25
86
416
171
993
2.07
12.80
3.5
2.8
4.68
4.68
e6/l
0.00
156
895
85
371
2.54
12.56
3.0
2.4
25.99
31.93
u/l
1.43
75
306
243
1616
1.94
12.21
2.7
2.2
74.62
78.04
nmol/l
1.01
210
1415
238
1573
1.94
12.17
5.8
4.1
264.77
136.91
e6/l
0.34
195
1165
78
335
2.56
11.89
2.6
1.7
1.76
1.61
%
0.46
62
283
321
2367
1.91
11.53
4.8
3.2
80.20
53.78
u/l
2.24
298
2183
204
1301
1.93
11.44
3.5
3.1
7.40
7.37
mmol/l
0.03
163
1064
85
389
2.41
11.30
4.8
2.8
4.41
4.30
kpa
0.23
80
370
80
357
2.46
11.23
2.1
1.9
344.93
376.03
nmol/l
0.75
73
319
267
1869
1.87
11.14
3.1
2.8
—
—
—
0
0
282
2014
1.86
10.99
5.7
4.2
0.00
0.00
estimate
-0.00
43
376
280
1996
1.86
10.97
5.7
4.2
0.00
0.00
estimate
0.50
48
423
366
2845
1.94
10.90
4.5
3.7
14.95
15.02
pmol/l
0.20
333
2512
460
3896
2.44
10.78
34.3
17.4
24.55
26.86
mg/l
1.05
430
3203
84
393
2.35
10.60
3.0
2.7
65.50
65.87
g/l
0.16
74
353
177
1103
1.91
10.46
3.7
2.9
5092.40
10054.60
umol/l
0.69
145
953
95
472
2.24
10.41
2.9
2.8
8.83
9.29
umol/l
0.10
88
415
197
1274
1.87
10.36
3.6
3.2
680.70
235.69
mg/l
0.49
132
857
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
46
161
3.04
10.30
2.4
2.2
0.38
0.35
u/ml
0.15
29
86
74
334
2.41
10.11
3.7
3.8
110.06
87.91
ng/l
0.95
64
292
275
1990
1.80
9.88
7.4
5.7
0.00
0.00
estimate
-0.00
46
381
68
303
2.43
9.54
2.3
1.6
—
—
—
0
0
203
1355
1.81
9.46
4.1
3.8
10.86
9.92
mg/mmol
0.12
128
873
66
292
2.44
9.40
3.5
4.1
1.07
1.82
mmol/l
0.54
49
225
162
1010
1.87
9.39
2.0
1.8
71970153.16
6985727.70
pmol/l
0.43
132
816
423
3534
2.01
9.18
6.1
4.5
2.23
2.01
mu/l
0.58
380
3159
72
338
2.31
8.97
1.6
1.7
—
—
—
0
0
83
417
2.18
8.78
2.4
2.1
0.21
0.20
g/l
0.21
74
382
68
318
2.31
8.54
3.5
4.0
5.24
5.15
kpa
0.34
63
310
145
899
1.85
8.43
3.0
3.1
2.46
2.46
mmol/l
0.09
128
780
367
2964
1.79
8.42
5.4
4.2
16.54
14.30
mm/h
1.60
335
2699
144
894
1.84
8.33
6.2
4.7
1.01
1.02
kg/l
0.68
29
139
155
985
1.81
8.30
2.9
2.5
—
—
—
0
0
464
4078
2.17
7.75
43.5
20.7
139.17
139.55
mmol/l
1.99
454
3962
464
4087
2.15
7.56
44.0
20.8
4.02
4.01
mmol/l
0.26
452
3970
31
105
3.07
7.36
1.4
1.4
—
—
—
0
0
31
105
3.07
7.36
1.4
1.4
—
—
—
0
0
253
1922
1.61
6.63
3.1
2.5
—
—
—
0
0
40
166
2.53
6.53
3.3
2.1
10.70
10.54
g/l
0.09
34
143
214
1577
1.60
6.27
6.4
4.5
—
—
—
0
0
37
153
2.53
6.09
3.8
3.8
45.16
39.27
mg/l
0.30
31
120
37
153
2.53
6.09
3.8
3.8
51.21
108.25
mg/l
0.70
31
118
34
136
2.60
5.99
4.0
2.9
0.73
0.90
nmol/l
1.40
28
109
87
508
1.85
5.97
11.7
8.8
—
—
—
0
0
161
1123
1.62
5.84
6.8
4.4
0.00
0.00
estimate
-0.00
43
367
37
158
2.44
5.71
1.4
1.2
—
—
—
0
0
12
16
7.65
5.66
8.7
2.2
186.00
85.36
umol/l
—
5
11
427
3763
1.72
5.51
6.2
4.9
6.35
6.11
mmol/l
2.56
384
3363
416
3646
1.67
5.42
8.7
6.4
43.32
41.15
mmol/mol
3.49
386
3331
454
4083
1.82
5.30
16.9
11.0
25.67
25.03
u/l
0.25
438
3913
110
716
1.68
5.16
1.2
1.2
0.77
1.46
u/ml
1.28
21
189
39
180
2.26
5.08
3.4
2.0
—
—
—
0
0
88
545
1.74
4.94
2.8
3.8
265.66
245.67
u/l
0.42
82
512
464
4224
1.84
4.87
50.1
25.3
232.08
238.89
e9/l
1.37
450
4108
464
4226
1.83
4.83
50.0
25.3
4.27
4.41
e12/l
7.36
452
4093
464
4226
1.83
4.83
50.7
25.4
38.23
39.42
%
3.09
420
3898
39
184
2.21
4.83
2.9
3.1
4.04
4.44
pmol/l
2.32
32
161
464
4227
1.83
4.82
50.4
25.4
128.27
133.29
g/l
10.13
454
4141
66
387
1.81
4.46
6.4
4.0
1.20
1.22
mmol/l
2.05
56
339
76
482
1.67
3.91
5.6
3.9
—
—
—
0
0
20
78
2.63
3.76
1.3
1.3
—
—
—
0
0
37
190
2.02
3.73
4.0
4.8
23.97
25.17
mmol/l
0.95
32
182
424
3839
1.54
3.72
6.3
5.2
2.18
2.57
mmol/l
16.05
388
3457
17
61
2.85
3.72
1.5
1.7
—
—
—
0
0
400
3583
1.49
3.66
5.1
4.1
1.36
1.26
mmol/l
2.42
363
3203
15
53
2.88
3.38
4.1
3.4
—
804.50
—
0
6
409
3700
1.47
3.37
5.7
4.6
1.33
1.42
mmol/l
4.79
374
3324
21
90
2.39
3.28
1.4
1.6
—
—
—
0
0
10
24
4.23
3.21
1.0
1.3
—
—
—
0
0
411
3737
1.46
3.16
5.7
4.6
4.01
4.43
mmol/l
12.82
379
3392
23
107
2.20
3.01
1.7
1.7
—
—
—
0
0
9
22
4.14
2.89
3.0
1.8
171.11
89.91
umol/l
—
9
22
23
109
2.16
2.89
1.7
1.7
—
—
—
0
0
13
47
2.81
2.83
1.6
1.8
—
—
—
0
0
24
117
2.10
2.81
1.6
1.2
0.96
2.33
u/ml
—
5
8
27
138
2.01
2.80
2.5
1.5
—
—
—
0
0
33
182
1.87
2.76
2.2
1.7
—
—
—
0
0
24
118
2.08
2.76
1.4
1.2
—
—
—
0
0
21
98
2.19
2.74
2.2
2.1
128.06
126.91
g/l
0.08
16
70
24
119
2.07
2.70
1.4
1.2
—
—
—
0
0
13
49
2.69
2.64
2.0
1.6
—
—
—
0
0
13
49
2.69
2.64
2.0
1.6
—
—
—
0
0
78
548
1.50
2.61
1.3
1.3
55.30
39.61
iu/ml
0.23
27
185
15
62
2.46
2.56
6.9
7.1
7.07
6.99
mmol/l
0.04
15
49
35
202
1.78
2.55
2.1
1.8
—
—
—
0
0
19
88
2.20
2.54
1.4
1.4
—
—
—
0
0
21
103
2.08
2.45
3.2
2.4
15.71
15.56
%
—
10
43
24
124
1.98
2.44
1.5
2.4
160.73
102.78
ug/min
—
9
72
220
1862
1.31
2.40
5.0
5.4
2.72
3.81
ug/l
0.67
190
1637
5
8
6.30
2.37
4.0
1.1
—
—
—
0
0
393
3617
1.34
2.25
32.7
16.4
69.33
73.15
ml/min/173m2
2.57
351
3018
18
86
2.13
2.25
1.4
1.3
2.56
7.66
u/ml
—
5
16
7
19
3.72
2.15
1.7
1.3
4.13
5.28
umol/l
—
7
13
11
42
2.65
2.15
1.1
1.1
—
—
—
0
0
13
55
2.40
2.13
1.3
1.2
—
—
—
0
0
38
239
1.64
2.08
1.5
1.9
1.55
1.56
g/l
0.04
33
211
7
20
3.53
2.06
2.1
1.5
58.29
60.41
ug/l
—
7
20
31
185
1.72
2.06
3.4
3.1
—
—
—
0
0
27
156
1.77
2.00
1.4
1.3
—
—
—
0
0
8
27
2.99
1.94
2.1
1.5
—
—
—
0
0
21
114
1.88
1.90
1.6
1.4
318.85
257.92
ug/g
0.53
13
66
27
159
1.74
1.89
2.4
1.9
38.27
38.43
u/l
0.01
21
144
16
79
2.06
1.87
1.4
1.6
—
—
—
0
0
17
86
2.01
1.87
1.7
1.6
—
—
—
0
0
11
46
2.42
1.86
1.6
2.6
—
—
—
0
0
5
12
4.20
1.82
1.0
1.1
—
—
—
0
0
9
36
2.53
1.74
1.2
1.8
—
—
—
0
0
5
13
3.87
1.72
2.0
2.8
70060.00
33846.54
ug/l
—
5
13
21
119
1.80
1.68
1.6
1.3
—
—
—
0
0
6
19
3.18
1.66
1.8
1.2
—
—
—
0
0
14
69
2.06
1.66
1.3
1.7
—
—
—
0
0
5
14
3.59
1.62
1.0
1.1
180.82
153.54
iu/ml
—
5
14
19
106
1.82
1.61
1.8
2.0
—
—
—
0
0
15
77
1.98
1.60
1.9
1.8
—
—
—
0
0
8
33
2.45
1.54
2.3
2.1
—
—
—
0
0
352
3260
1.24
1.54
42.6
20.6
15.35
15.34
%
0.01
345
3207
174
1497
1.24
1.53
4.6
4.5
22.11
21.62
%
0.16
82
754
20
116
1.75
1.51
1.3
1.3
—
—
—
0
0
14
73
1.94
1.45
1.9
1.6
—
—
—
0
0
14
73
1.94
1.45
1.9
1.6
—
—
—
0
0
12
59
2.06
1.44
1.7
1.3
13926.57
31071.95
e6/l
—
7
37
65
497
1.35
1.42
3.8
4.3
3.56
36.85
ug/l
1.34
52
423
45
325
1.42
1.37
6.2
3.0
51.88
60.32
ml/min/173m2
1.47
26
144
6
23
2.63
1.37
1.0
1.0
—
—
—
0
0
9
44
2.06
1.27
1.0
1.7
—
—
—
0
0
14
77
1.84
1.26
1.6
1.8
—
—
—
0
0
67
526
1.31
1.24
1.4
1.3
46.51
11.97
u/ml
0.71
19
200
5
19
2.65
1.22
1.4
1.4
—
—
—
0
0
11
200
0.54
1.22
2.2
1.7
—
—
—
0
0
6
26
2.32
1.19
1.0
1.6
—
—
—
0
0
6
26
2.32
1.19
1.0
1.6
—
—
—
0
0
6
26
2.32
1.19
1.2
1.2
—
—
—
0
0
10
50
2.02
1.17
1.5
1.3
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
5
20
2.51
1.15
1.0
1.2
—
—
—
0
0
18
111
1.64
1.13
1.6
1.5
0.18
0.14
iu/ml
—
5
25
26
176
1.50
1.12
1.7
1.9
—
—
—
0
0
8
40
2.02
1.12
1.5
1.2
—
—
—
0
0
5
21
2.39
1.09
1.0
1.1
—
—
—
0
0
7
33
2.14
1.06
1.0
1.5
—
—
—
0
0
9
46
1.97
1.04
1.0
1.0
—
—
—
0
0
9
46
1.97
1.04
1.0
1.7
—
—
—
0
0
63
507
1.28
0.99
5.5
4.8
32.74
32.08
%
0.19
43
339
11
62
1.79
0.95
2.2
1.7
—
—
—
0
0
9
52
1.74
0.92
1.7
1.2
—
—
—
0
0
11
63
1.76
0.90
6.5
5.4
12.42
12.27
mg/l
0.04
11
58
23
161
1.45
0.88
1.7
1.7
—
—
—
0
0
8
45
1.79
0.84
1.0
1.1
—
—
—
0
0
121
1065
1.18
0.82
2.9
3.1
0.66
0.84
ug/l
1.66
85
727
23
165
1.41
0.79
1.1
1.1
327.14
148.04
iu/ml
—
7
61
5
99
0.50
0.78
3.4
1.5
7.72
2.79
mg/l
—
5
79
5
25
2.01
0.73
1.4
1.9
—
—
—
0
0
5
25
2.01
0.73
1.0
1.4
—
—
—
0
0
13
84
1.56
0.72
1.9
1.6
2.38
6.62
iu/l
—
5
21
15
101
1.50
0.71
2.2
1.6
—
—
—
0
0
5
26
1.93
0.71
3.2
4.0
—
—
—
0
0
5
26
1.93
0.71
1.4
1.8
—
—
—
0
0
11
69
1.61
0.69
1.9
1.6
—
—
—
0
0
38
306
1.26
0.64
2.3
2.3
12.69
12.40
nmol/l
0.08
31
263
5
29
1.73
0.64
1.2
1.8
—
—
—
0
0
0
20
0.00
0.60
0.0
1.6
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
18
131
1.39
0.60
1.3
1.6
—
—
—
0
0
8
55
1.46
0.56
1.1
1.5
—
—
—
0
0
9
60
1.51
0.54
1.7
1.4
—
—
—
0
0
7
46
1.53
0.48
1.1
1.4
—
—
—
0
0
108
986
1.12
0.46
1.7
1.7
1.44
1.31
mmol/l
0.80
92
797
7
49
1.43
0.46
2.1
2.6
—
—
—
0
0
7
51
1.38
0.44
6.7
4.1
—
—
—
0
0
8
56
1.44
0.42
1.1
1.5
—
—
—
0
0
8
56
1.44
0.42
1.1
1.5
—
—
—
0
0
8
56
1.44
0.42
1.1
1.5
—
—
—
0
0
5
32
1.57
0.42
1.4
1.8
—
—
—
0
0
8
57
1.41
0.42
1.1
1.5
—
—
—
0
0
49
427
1.16
0.42
1.7
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
1.13
—
0
12
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
1.6
—
—
—
0
0
0
19
0.00
0.39
0.0
5.5
—
—
—
0
0
0
19
0.00
0.39
0.0
1.4
—
—
—
0
0
9
66
1.37
0.38
1.1
1.0
—
—
—
0
0
28
330
0.84
0.35
1.4
1.4
—
—
—
0
0
6
46
1.31
0.33
2.3
1.6
—
—
—
0
0
7
98
0.71
0.31
1.3
1.4
—
—
—
0
0
7
56
1.25
0.29
1.1
1.5
—
—
—
0
0
8
62
1.29
0.28
1.0
1.3
—
332.43
—
0
28
8
62
1.29
0.28
2.8
3.0
13.50
33.86
u/ml
—
8
62
8
67
1.20
0.26
1.5
1.4
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
—
—
0
0
7
60
1.17
0.18
1.3
3.1
—
27.32
—
0
19
12
101
1.19
0.16
1.4
1.7
—
—
—
0
0
8
68
1.18
0.16
1.1
1.1
—
—
—
0
0
8
70
1.15
0.16
1.5
1.1
—
—
—
0
0
8
73
1.10
0.15
3.5
3.0
61.13
60.16
%
—
8
73
15
144
1.04
0.00
1.3
1.0
—
—
—
0
0
12
117
1.03
0.00
5.2
4.4
31.43
30.43
mg/l
0.04
12
76
19
193
0.98
0.00
1.3
1.3
—
53.45
—
0
15
14
142
0.99
0.00
6.1
3.1
32.74
47.90
u/ml
0.49
14
137
0
5
0.00
0.00
0.0
4.8
—
60.30
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
8
84
0.95
-0.00
1.4
1.2
507.88
517.49
mg/l
—
8
79
0
9
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
52
0.96
-0.00
1.2
1.7
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint HYPOTE_DRUGS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HYPOTE_DRUGS | 2.009 [1.68, 2.4] | < 0.001 |
| Birth year | 0.997 [0.99, 1.01] | 0.442 |
During the follow-up period (1.1.1998 — 31.12.2019), 1003 out of 1827 females with HYPOTE_DRUGS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| HYPOTE_DRUGS | 2.434 [1.91, 3.11] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 948 out of 1685 males with HYPOTE_DRUGS died.
Mortality risk
Mortality risk for people of age
years, who have HYPOTE_DRUGS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.193% | 0.515% |
| 5 | 1.172% | 2.872% |
| 10 | 2.94% | 6.92% |
| 15 | 5.423% | 12.823% |
| 20 | 9.768% | 21.299% |
Relationships between endpoints
↥Index endpoint: HYPOTE_DRUGS – Hypotension due to drugs
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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