Ulcerative rectosigmoiditis

ULCERRECT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K51.3
  • Cause of death: ICD-10 K51.3

2 out of 7 registries used, show all original rules.

3489

4. Check minimum number of events

None

3489

5. Include endpoints

None

3489

6. Filter based on genotype QC (FinnGen only)

3489

Control definitions (FinnGen only)

Control exclude
K11_ENERCOLNONINF

Extra metadata

First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K51
Name in latin
Rectosigmoiditis ulcerosa [chronica]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 19206 8881 10235
Only index persons 18415 8651 9764
Unadjusted period prevalence (%)
Whole population 0.27 0.25 0.29
Only index persons 0.35 0.32 0.37
Median age at first event (years)
Whole population 44.63 42.34 46.50
Only index persons 43.93 41.94 45.70

-FinnGen-

Key figures

All Female Male
Number of individuals 3489 1804 1685
Unadjusted period prevalence (%) 0.68 0.61 0.74
Median age at first event (years) 45.24 41.50 49.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3181
Matched controls
31809
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K51.3
ICD-10 Finland
Ulcerative (chronic) rectosigmoiditis
+∞
323.0
3181
*
K51
ICD-10 Finland
Ulcerative colitis
3145.4
323.0
549
*
H02AB07
ATC
prednisone; oral
6.6
323.0
1024
2131
K51.1
ICD-10 Finland
Ulcerative (chronic) ileocolitis
+∞
323.0
652
*
L01BB02
ATC
mercaptopurine; oral
347.3
323.0
420
14
A07EA01
ATC
prednisolone; rectal
868.0
323.0
383
5
A07EC01
ATC
sulfasalazine; oral, rectal
11.2
323.0
897
1076
K51.2
ICD-10 Finland
Ulcerative (chronic) proctitis
2892.4
323.0
954
5
A07EC02
ATC
mesalazine; oral, rectal
2968.4
323.0
2980
153
K51.5
ICD-10 Finland
Left sided colitis
10780.2
323.0
1928
*
A07EA02
ATC
hydrocortisone; rectal
591.6
323.0
1639
57
K51.8
ICD-10 Finland
Other ulcerative colitis
2076.8
323.0
776
5
K51.0
ICD-10 Finland
Ulcerative (chronic) pancolitis
+∞
323.0
459
*
H02AB06
ATC
prednisolone; systemic
9.5
323.0
2552
9532
A07EA06
ATC
budesonide; oral, local oral
243.1
323.0
1190
78
UJF32
NOMESCO Finland
Coloscopy
32.2
323.0
2579
3730
UJF30
NOMESCO Finland
Ileoscopy through colon
19.6
323.0
1293
1072
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
14.8
323.0
1001
958
L04AX01
ATC
azathioprine; systemic
79.1
323.0
1383
306
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
+∞
323.0
2962
*
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
7258.1
323.0
1804
5
D94
ICPC
Chronic enteritis/ulcerative colitis
316.7
286.4
287
10
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.3
277.5
1371
4766
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
+∞
272.9
258
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
31.8
264.2
355
125
K50.1
ICD-10 Finland
Crohn disease of large intestine
878.6
251.6
244
*
K50.8
ICD-10 Finland
Other Crohn disease
+∞
250.3
237
*
K50.9
ICD-10 Finland
Crohn disease, unspecified
750.9
216.4
211
*
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
233.8
213.5
218
10
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
85.9
206.6
231
29
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
176.7
168
*
A07EC03
ATC
olsalazine; oral
592.4
172.0
169
*
5561A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) ileocolitis
+∞
157.6
150
*
ZX120
NOMESCO Finland
Intravenous
5.1
156.2
552
1267
J01MA02
ATC
ciprofloxacin; systemic
2.8
155.6
1483
7543
K50.0
ICD-10 Finland
Crohn disease of small intestine
485.4
141.4
140
*
P01AB01
ATC
metronidazole; oral, rectal
2.6
140.3
1516
8147
56310
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Ulcerative colitis
+∞
138.5
132
*
JFH30
NOMESCO Finland
Total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
626.6
123.1
121
*
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
32.7
101.8
135
43
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
101.3
991
4804
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
155.0
99.7
105
7
5568X
ICD-9 Finland
Idiopathic proctocolitis, Other ulcerative colitis
+∞
98.4
94
*
5562A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctitis
+∞
94.2
90
*
L04AB04
ATC
adalimumab; parenteral
11.4
92.0
178
165
A02BC02
ATC
pantoprazole; systemic
2.2
91.9
2068
14668
A06AC01
ATC
ispaghula (psylla seeds); oral
2.6
89.6
828
3844
4AA12
NOMESCO Finland
NA
303.6
87.1
88
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.6
85.5
774
3537
4AB02
NOMESCO Finland
NA
106.4
85.4
93
9
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
45.1
85.1
105
24
WX002
NOMESCO Finland
Sedation and analgesia
2.5
76.3
687
3105
M07.5
ICD-10 Finland
Arthropathy in ulcerative colitis
755.7
75.6
74
*
JFH33
NOMESCO Finland
Total colectomy, mucosal proctectomy, ileoanal anastomosis and ileostomy
713.7
71.4
70
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
67.9
1311
8310
L04AD01
ATC
ciclosporin; systemic
8.0
64.1
150
195
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
63.9
628
2940
253
Kela drug reimbursment
NA
+∞
62.7
60
*
3042
Kela drug reimbursment
NA
+∞
62.7
60
*
5560A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) enterocolitis
+∞
60.6
58
*
C05AA08
ATC
fluocortolone; rectal, topical
2.5
59.6
540
2414
K62.8
ICD-10 Finland
Other specified diseases of anus and rectum
16.9
55.3
89
54
JFH11
NOMESCO Finland
Laparoscopic colectomy
+∞
54.3
52
*
K83.0
ICD-10 Finland
Cholangitis
11.3
49.7
95
86
JFH20
NOMESCO Finland
Proctocolectomy and ileostomy
495.3
49.5
49
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
64.4
49.3
57
9
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.9
47.9
211
574
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.9
47.8
208
560
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.7
47.3
222
637
L04AB06
ATC
golimumab; parenteral
13.0
47.0
84
66
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
46.4
375
1560
K51.4
ICD-10 Finland
Inflammatory polyps
+∞
45.9
44
*
JGB50
NOMESCO Finland
Mucosal proctectomy and ileoanal anastomosis
453.9
45.4
45
*
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.3
45.2
482
2310
L04AC05
ATC
ustekinumab; parenteral
40.7
44.8
56
14
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
44.2
319
1240
4AA33
NOMESCO Finland
NA
+∞
42.8
41
*
A07DA03
ATC
loperamide; oral
4.3
42.4
163
391
3005
Kela drug reimbursment
Tofacitinib
31.6
42.4
56
18
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.3
41.7
131
254
C10AC01
ATC
colestyramine; oral
6.0
41.6
119
206
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
41.6
662
3753
JFF10
NOMESCO Finland
Loop enterostomy
23.1
41.0
59
26
N02BE01
ATC
paracetamol; systemic, rectal
1.8
39.2
2585
22438
H02AB09
ATC
hydrocortisone; systemic
5.3
39.1
123
239
Z93.2
ICD-10 Finland
Ileostomy status
33.8
38.5
50
15
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.7
37.7
172
482
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.1
37.6
219
739
1370
FHL
Colonoscopy, whole colon
17.7
37.6
59
34
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
22.4
36.6
53
24
A02BC03
ATC
lansoprazole; oral
1.8
35.7
811
5163
UJF92
NOMESCO Finland
Capsular endoscopy
6.1
35.7
100
169
A05AA02
ATC
ursodeoxycholic acid; oral
6.6
35.4
93
144
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.4
35.1
321
1416
L04AA29
ATC
tofacitinib; oral
27.0
35.0
48
18
56902
ICD-8 Finland
Other diseases of intestines and peritoneum, Proctitis haemorrhagica (ulcerosa)
+∞
34.4
33
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
34.3
34.1
44
13
H02AB04
ATC
methylprednisolone; systemic
2.0
33.5
456
2414
M09.2*K51.9
ICD-10 Finland
Juvenile arthritis in ulcerative colitis
+∞
33.4
32
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.3
32.4
101
195
K50
ICD-10 Finland
Crohn disease [regional enteritis]
+∞
32.3
31
*
K92.1
ICD-10 Finland
Melaena
3.3
32.1
169
531
WVA20
NOMESCO Finland
Medicine administration
5.1
32.0
104
210
UJF34
NOMESCO Finland
Left colonoscopy
12.3
31.4
57
47
D16
ICPC
Rectal bleeding
5.2
30.3
96
189
L04AA33
ATC
vedolizumab; parenteral
+∞
30.2
29
*
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
17.9
29.6
46
26
N02AX02
ATC
tramadol; systemic, rectal
1.6
29.5
1163
8521
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.1
28.5
342
1713
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
27.6
1020
7329
JF1BD
NOMESCO Finland
Very extensive small bowel CT
17.4
27.5
43
25
M07.4*K50.9
ICD-10 Finland
Arthropathy in Crohn's disease [regional enteritis]
+∞
27.1
26
*
A07AA09
ATC
vancomycin; oral
7.2
27.0
66
93
A02BC05
ATC
esomeprazole; systemic
1.5
25.8
1107
8208
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
24.9
377
2061
A02BC01
ATC
omeprazole; systemic
1.6
24.7
731
4938
UJG02
NOMESCO Finland
Proctoscopy
4.1
24.3
97
243
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
24.1
1069
7953
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.7
24.0
175
683
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.1
23.4
281
1403
3AC01
NOMESCO Finland
NA
6.5
22.9
60
94
L04AA01
ATC
[U] ciclosporin; systemic
5.1
22.7
72
143
M45
ICD-10 Finland
Ankylosing spondylitis
3.7
22.4
99
272
5586X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis[KROONINEN INFLAMMATOORINEN SUOLISTOSAIRAUS, NUD]
+∞
21.9
21
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
21.8
349
1947
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
21.0
1319
10468
D18
ICPC
Change in faeces/bowel movements
4.2
21.0
80
193
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.8
20.3
136
502
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
4.8
20.3
68
144
JN3AD
NOMESCO Finland
Abdominal CT examination
2.2
20.1
212
997
C05AA01
ATC
hydrocortisone; rectal, topical
2.5
19.8
155
629
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
4.6
19.7
69
153
Z93
ICD-10 Finland
Artificial opening status
17.8
19.5
30
17
B01AB05
ATC
enoxaparin; parenteral
1.5
19.5
750
5353
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
19.4
474
3017
R50.9
ICD-10 Finland
Fever, unspecified
1.8
19.4
393
2367
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.8
19.0
127
471
1490
FHL
Sigmoideoscopy (fiberscope)
15.9
18.8
30
19
JFG73
NOMESCO Finland
Excision of ileal pelvic pouch
+∞
18.8
18
*
JGB40
NOMESCO Finland
Excision of rectum and end ileostomy
+∞
18.8
18
*
SPAT1263
SPAT
Sampling
1.4
18.7
1159
9110
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.2
18.4
201
963
JH1CG
NOMESCO Finland
Extensive MRI of perianal area
9.6
18.3
37
39
D06BX01
ATC
metronidazole; topical
1.9
18.2
288
1596
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
4.7
18.1
62
135
JF2AB
NOMESCO Finland
Colongraphy with X-ray
14.4
18.1
30
21
A03CA02
ATC
clidinium and psycholeptics; oral
2.5
18.0
148
619
K60.3
ICD-10 Finland
Anal fistula
3.7
17.8
77
209
JAH00
NOMESCO Finland
Laparotomy
3.4
17.7
87
262
JFG40
NOMESCO Finland
Revision of enterostomy or colostomy without laparotomy
18.7
17.3
26
14
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.6
17.3
78
220
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.4
16.9
50
93
JFF13
NOMESCO Finland
Terminal enterostomy
25.7
16.9
23
9
J01MA12
ATC
levofloxacin; systemic
1.6
16.9
453
2951
56399
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Other
+∞
16.7
16
*
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
27.7
16.5
22
8
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.5
16.2
127
517
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
3.6
15.8
70
195
ZXC86
NOMESCO Finland
Use of endoscopic device
8.2
15.5
34
42
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.1
15.3
176
864
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
3.3
15.0
76
236
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
14.7
185
942
Z43.2
ICD-10 Finland
Attention to ileostomy
25.1
14.7
20
8
JHA00
NOMESCO Finland
Anal or perianal incision
3.9
14.4
59
154
JF1AD
NOMESCO Finland
Small bowel CT
8.9
14.4
30
34
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
6.2
14.4
38
62
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.7
14.3
61
165
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
14.0
1052
8441
M05BA04
ATC
alendronic acid; oral
2.2
14.0
148
699
WW200
NOMESCO Finland
Immunization
2.7
14.0
96
365
J01FA10
ATC
azithromycin; systemic
1.3
13.8
1681
14535
K56.7
ICD-10 Finland
Ileus, unspecified
4.4
13.7
49
113
-
ICD-10 Finland
NA
3.1
13.7
74
241
R01AD08
ATC
fluticasone; nasal
1.4
13.7
778
5947
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.8
13.6
225
1265
K52.1
ICD-10 Finland
Toxic gastroenteritis and colitis
75.4
13.6
15
*
A06AC51
ATC
ispaghula, combinations; systemic
2.3
13.5
132
600
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.8
13.5
239
1374
1380
FHL
Colonoscopy, left side
34.2
13.5
17
5
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
13.3
438
2988
J01DB01
ATC
cefalexin; oral
1.4
13.3
2413
22116
TJF80
NOMESCO Finland
Ostomy education
4.9
13.2
42
86
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
13.2
1052
8504
SPAT1262
SPAT
Handing over of treatment supplies
1.5
13.1
444
3052
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
12.9
694
5237
A02BA02
ATC
ranitidine; systemic
1.5
12.8
450
3119
JFA38
NOMESCO Finland
Endoscopic dilatation of small intestine
130.5
12.4
13
*
E0000UV
ATC
NA
1.3
12.4
1024
8304
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
3.0
12.3
70
235
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.0
12.3
70
235
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
3.1
12.0
65
213
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
1.8
12.0
220
1280
R01AD12
ATC
fluticasone furoate; nasal
1.4
11.9
828
6530
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
11.8
263
1623
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.4
11.7
95
397
D11
ICPC
Diarrhoea
1.6
11.7
301
1934
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.9
11.4
157
830
UJD02
NOMESCO Finland
Gastroscopy
2.2
11.3
115
537
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
3.8
11.3
46
121
D07AC01
ATC
betamethasone; topical
1.3
11.3
861
6874
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.2
11.1
113
526
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
11.1
223
1338
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
11.1
118
562
JHW96
NOMESCO Finland
Other operation on anus or perianal tissue
8.0
11.1
24
30
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.0
11.1
43
109
Y0599
ICD-8 Finland
Investigation of digestive system
3.7
11.0
47
129
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.3
11.0
99
437
A98
ICPC
Health maint/preventive medicine
1.7
10.8
3002
28944
6419
FHL
Other measure in this category
21.5
10.7
15
7
TJJ00
NOMESCO Finland
Percutaneous needle biopsy of liver
12.9
10.6
18
14
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
10.6
189
1093
JHD20
NOMESCO Finland
Incision of fistula-in-ano
4.1
10.6
40
99
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.8
10.6
190
1098
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
8.0
10.6
23
29
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
10.5
1095
9132
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.7
10.5
229
1404
K73.2
ICD-10 Finland
Chronic active hepatitis, not elsewhere classified
8.5
10.5
22
26
N03AX16
ATC
pregabalin; oral
1.4
10.5
555
4164
JFB00
NOMESCO Finland
Partial resection of small intestine
3.9
10.5
41
105
K56.0
ICD-10 Finland
Paralytic ileus
5.2
10.4
31
60
K61.0
ICD-10 Finland
Anal abscess
3.0
10.4
57
190
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
3.4
10.2
48
143
JHD00
NOMESCO Finland
Anal dilatation
4.8
10.2
33
70
UJH02
NOMESCO Finland
Anoscopy
2.1
10.1
113
548
A07AA02
ATC
nystatin; oral
1.9
10.1
137
722
WZA90
NOMESCO Finland
Other doctors statement
1.4
10.0
597
4568
D99
ICPC
Disease digestive system other
4.1
10.0
37
90
A03BA03
ATC
hyoscyamine; oral
5.1
10.0
30
59
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.9
9.9
31
64
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
9.9
507
3779
D29
ICPC
Digestive symptom/complaint other
2.8
9.9
60
215
XX6XT
NOMESCO Finland
Other intravascular therapy with radiological guidance
8.1
9.8
21
26
B03BA03
ATC
hydroxocobalamin; parenteral
2.1
9.7
108
524
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
2.6
9.6
70
278
UJK02
NOMESCO Finland
ERCP
2.8
9.6
58
207
B02.9
ICD-10 Finland
Zoster without complication
2.0
9.5
118
602
0093A
ICD-9 Finland
Ill-defined intestinal infections, Diarrhoea of presumed infectious origin
3.5
9.5
42
120
J01MA01
ATC
ofloxacin; systemic
1.7
9.4
187
1119
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.6
9.4
68
270
6410
FHL
Panprococolectomy and ileostomy
+∞
9.4
9
*
JGB61
NOMESCO Finland
Laparoscopic excision of rectum and ileoanal anastomosis
+∞
9.4
9
*
J01CA04
ATC
amoxicillin; systemic
1.3
9.4
2359
21903
L88
ICD-10 Finland
Pyoderma gangrenosum
12.4
9.3
16
13
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
12.4
9.3
16
13
SPAT1153
SPAT
Removal of sutures
1.3
9.3
751
6018
K74.3
ICD-10 Finland
Primary biliary cirrhosis
6.9
9.3
22
32
SPAT1131
SPAT
Colonoscopy
2.3
9.3
82
358
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.4
9.3
79
339
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
9.3
2037
18565
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
2.4
9.2
76
322
UJF02
NOMESCO Finland
Peroral enteroscopy
5.5
9.2
26
48
UJK12
NOMESCO Finland
Peroral cholangioscopy
13.7
9.2
15
11
K30
ICD-10 Finland
Functional dyspepsia
1.6
8.9
238
1544
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
0.5
8.9
71
1374
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
8.8
377
2715
UJF32
SPAT
NA
3.0
8.7
48
162
SPAT1325
SPAT
Vaccination
1.3
8.7
757
6127
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
3.1
8.6
44
142
M13.9
ICD-10 Finland
Arthritis, unspecified
1.7
8.4
174
1056
SPAT1255
SPAT
Intravenous administration of medicine
1.8
8.4
151
877
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
8.4
771
6287
JFG96
NOMESCO Finland
Other operation on intestinal stoma or pouch
+∞
8.3
8
*
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
+∞
8.3
8
*
5563A
ICD-9 Finland
Idiopathic proctocolitis, Ulcerative (chronic) proctosigmoiditis
+∞
8.3
8
*
J05AB01
ATC
aciclovir; systemic
1.4
8.3
501
3832
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
8.3
1483
13107
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
6.2
8.3
21
34
J01AA02
ATC
doxycycline; systemic
1.3
8.3
2146
19794
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
8.2
316
2224
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.1
1853
16818
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
8.1
1328
11611
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
5.7
8.1
22
39
JFA56
NOMESCO Finland
Faecal microbiota transplantation
33.4
8.1
10
*
JD1AB
NOMESCO Finland
Gastro-duodenography with X-ray
33.4
8.1
10
*
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.2
8.0
1219
10562
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.1
8.0
89
435
B81
ICPC
Anaemia vit B12/folate deficiency
2.3
8.0
71
313
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.1
8.0
84
402
N02AA05
ATC
oxycodone; systemic
1.5
8.0
275
1896
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
7.9
270
1857
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.7
7.9
159
957
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.9
878
7327
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
4.2
7.9
28
67
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
2.5
7.6
58
239
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.3
7.6
69
310
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
2.7
7.6
50
190
SPAT1125
SPAT
Stoma care and guidance
3.4
7.6
34
100
JFG50
NOMESCO Finland
Laparotomy with revision of enterostomy or colostomy
25.1
7.6
10
*
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
3.5
7.6
33
95
UJF30
SPAT
NA
5.1
7.5
22
43
K55.9
ICD-10 Finland
Vascular disorder of intestine, unspecified
8.9
7.5
15
17
JFF11
NOMESCO Finland
Laparoscopic loop enterostomy
7.1
7.5
17
24
Z01.2
ICD-10 Finland
Dental examination
1.2
7.4
1088
9366
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
7.4
1619
14556
JFH31
NOMESCO Finland
Laparoscopic total colectomy, mucosal proctectomy and ileoanal anastomosis without ileostomy
80.3
7.4
8
*
SPAT1301
SPAT
No procedures
1.3
7.4
732
6011
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.3
7.4
468
3603
5781B
ICD-9 Finland
Gastro-intestinal haemorrhage, Melaena[HAEMORRHAGIA EX ANO]
13.4
7.4
12
9
WX402
NOMESCO Finland
General anaesthesia
1.4
7.4
399
2994
N05CF01
ATC
zopiclone; oral
1.3
7.3
713
5843
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
7.3
708
5793
M07.4
ICD-10 Finland
Arthropathy in Crohn disease [regional enteritis]
+∞
7.3
7
*
5589X
ICD-9 Finland
Other non-infective gastro-enteritis and colitis, Other and unspecified non-infectious gastro-enteritis and colitis
+∞
7.3
7
*
S18
ICPC
Laceration/cut
1.2
7.2
981
8367
K52.80
ICD-10 Finland
(Hemorrhagic) colitis caused by antibiotics
30.1
7.1
9
*
E000001
ATC
NA
1.3
7.1
495
3864
WX110
NOMESCO Finland
Local anesthesy
1.2
7.1
1963
18053
H15.1
ICD-10 Finland
Episcleritis
2.8
7.1
43
156
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
7.1
670
5467
B80
ICPC
Iron deficiency anaemia
2.5
7.0
50
199
M03BX02
ATC
tizanidine; oral
1.2
7.0
1709
15500
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
7.0
207
1378
6451
FHL
Dilatation
4.3
7.0
24
56
R01AD09
ATC
mometasone; nasal
1.2
7.0
1187
10372
K91.8
ICD-10 Finland
Other postprocedural disorders of digestive system, not elsewhere classified
13.8
6.9
11
8
L88
ICPC
Rheumatoid/seropositive arthritis
2.0
6.8
85
439
NH3EA
NOMESCO Finland
Feet X-ray examination with load
2.4
6.8
55
234
R03AC02
ATC
salbutamol; inhalant
1.2
6.8
1372
12196
M25.9
ICD-10 Finland
Joint disorder, unspecified
3.6
6.8
28
78
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
6.7
531
4221
J01DA01
ATC
[U] cefalexin; systemic
1.2
6.7
1694
15393
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
3.0
6.7
35
116
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
4.3
6.7
23
54
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.2
6.7
65
302
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
6.7
256
1803
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
4.9
6.6
20
41
R05
ICPC
Cough
1.3
6.6
512
4058
K76.9
ICD-10 Finland
Liver disease, unspecified
3.1
6.6
34
112
KMAK
NOMESCO Finland
NA
1.2
6.6
1467
13154
E86
ICD-10 Finland
Volume depletion
2.6
6.5
44
171
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.3
6.5
54
234
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.4
6.5
51
215
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
10.0
6.5
12
12
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
10.0
6.5
12
12
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.7
6.5
130
784
J05AB11
ATC
valaciclovir; oral
1.4
6.5
297
2167
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.0
6.4
75
379
K55.1
ICD-10 Finland
Chronic vascular disorders of intestine
14.3
6.4
10
7
-60
ICPC
Result test/procedure
1.7
6.4
126
758
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
2.0
6.3
79
409
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
1.4
6.3
292
2131
D07AC13
ATC
mometasone; topical
1.3
6.3
684
5672
D07XC01
ATC
betamethasone, combinations; topical
1.4
6.3
266
1915
Z98.8
ICD-10 Finland
Other specified postsurgical states
3.0
6.3
33
111
F2682
NOMESCO Finland
NA
18.0
6.3
9
5
K52.0
ICD-10 Finland
Gastroenteritis and colitis due to radiation
+∞
6.2
6
*
M09.1*K50.9
ICD-10 Finland
Juvenile arthritis in Crohn's disease [regional enteritis]
+∞
6.2
6
*
M073, K519
ICD-10 Finland
NA
+∞
6.2
6
*
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.6
6.2
136
841
R11
ICD-10 Finland
Nausea and vomiting
1.6
6.2
163
1057
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
2.1
6.2
62
295
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
6.1
670
5556
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
6.1
203
1392
J01MA14
ATC
moxifloxacin; systemic
1.5
6.0
200
1370
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
3.0
6.0
31
103

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
794
1897
5.12
318.00
5.8
4.0
0.42
0.61
%
1.36
156
427
394
460
9.53
315.62
4.8
3.2
3.90
4.11
e9/l
0.87
394
460
831
2083
4.92
313.82
6.1
4.2
0.75
0.86
%
0.39
202
577
782
1868
5.11
312.92
6.3
4.2
0.06
0.44
%
0.82
162
452
398
477
9.29
312.33
5.1
3.4
57.00
56.99
%
0.01
398
477
806
1991
4.96
309.55
6.2
4.2
0.06
0.11
%
1.41
185
537
2209
2408
23.28
307.65
2.1
1.2
—
—
—
0
0
2786
14071
5.86
307.65
13.3
5.6
1.87
1.96
e9/l
2.85
2622
12484
2812
14143
6.09
307.65
13.5
5.8
0.19
0.19
e9/l
0.72
2642
12513
3271
20686
10.30
307.65
17.2
6.8
72.15
76.17
u/l
9.14
3212
19562
2727
2841
40.37
307.65
7.6
1.3
220.60
91.22
ug/g
37.21
2603
2200
2773
13603
6.06
307.65
13.2
5.5
0.56
0.57
e9/l
1.70
2593
11839
2507
12303
4.69
307.65
13.6
5.7
0.75
0.67
%
14.07
2412
11546
383
40
107.43
307.65
3.2
2.4
8.20
5.57
mg/l
2.97
328
29
2573
13238
4.59
307.65
13.5
5.7
28.80
28.56
%
0.63
2478
12419
2780
13643
6.11
307.65
13.3
5.5
0.04
0.04
e9/l
2.94
2603
11862
2374
10567
4.90
307.65
3.7
2.1
76.22
75.32
nmol/l
0.90
2286
9636
2101
8854
4.45
307.65
12.1
5.6
—
—
—
0
0
2556
12794
4.73
307.65
13.7
5.9
8.76
8.47
%
5.53
2468
12056
2702
10583
7.89
307.65
9.1
4.6
36.89
36.03
g/l
17.92
2619
9865
2543
12710
4.69
307.65
13.4
5.6
2.86
2.83
%
0.26
2454
11909
334
42
87.84
307.65
2.7
2.3
152.62
207.19
au/ml
—
48
8
2554
13059
4.57
307.65
12.7
5.5
56.93
56.79
%
0.28
2462
12294
2870
15786
5.61
307.65
15.0
8.8
3.90
4.07
e9/l
4.86
2682
13836
1528
6171
3.63
294.06
3.7
2.0
2.80
2.86
mg/l
0.45
1397
5264
1509
6419
3.38
260.86
10.2
4.1
—
—
—
0
0
159
55
30.24
240.33
2.1
1.2
9.91
8.98
mg/l
0.55
139
43
3014
20184
4.62
235.92
7.5
3.7
11.24
10.58
mm/h
2.07
2865
18831
2192
12237
3.13
227.46
16.1
8.5
0.00
0.00
e9/l
0.69
1982
9995
579
1516
4.38
201.34
1.5
1.2
—
—
—
0
0
168
0
+∞
176.57
2.5
0.0
23.56
—
mg/l
—
160
0
117
41
29.49
175.75
1.8
1.3
88.28
177.40
au/ml
—
18
5
931
3685
3.08
170.41
1.5
1.6
—
—
—
0
0
1637
9377
2.40
136.50
4.4
3.1
28.70
34.58
u/l
2.79
1478
8941
1054
5066
2.55
127.72
1.6
1.7
—
—
—
0
0
318
748
4.58
124.84
1.5
1.2
69.37
97.50
titre
1.36
32
64
1919
12342
2.23
114.90
3.8
2.7
103.32
117.80
ug/l
1.26
1824
11565
3376
28619
6.55
109.05
25.1
12.1
15.14
22.94
mg/l
62.78
2996
22224
2003
13606
2.11
98.02
7.0
6.0
10.44
11.28
umol/l
3.85
1937
12927
1362
8174
2.09
91.09
4.0
2.5
58.69
57.01
u/l
0.52
1292
7595
435
1579
3.00
88.43
1.8
1.8
1.21
1.31
g/l
0.65
407
1457
552
2279
2.69
88.09
4.5
3.5
—
—
—
0
0
702
3283
2.43
86.06
2.8
2.5
22.50
24.09
%
2.33
619
2835
507
2039
2.74
85.01
2.4
2.7
11.38
10.54
g/l
4.55
469
1869
781
3883
2.30
82.89
2.8
2.4
13.38
13.94
umol/l
1.33
742
3616
729
3569
2.32
79.92
2.8
2.4
2.42
2.35
g/l
2.63
697
3324
1637
11056
1.91
73.39
2.5
2.0
—
—
—
0
0
753
3867
2.21
72.84
1.6
1.3
549.95
510.57
titre
0.25
195
755
1126
6859
1.95
67.69
10.0
6.7
—
—
—
0
0
1063
6361
1.97
67.26
1.7
1.9
—
—
—
0
0
905
5183
2.01
64.54
2.6
1.6
8395484.53
35626846.62
pmol/l
1.62
810
4390
270
902
3.16
62.73
1.8
1.8
—
—
—
0
0
2375
18729
1.84
58.81
4.7
3.9
—
—
—
0
0
487
2304
2.29
56.31
2.6
2.2
0.23
0.22
g/l
4.07
455
2161
1113
7093
1.84
56.01
4.3
3.6
0.00
0.00
estimate
1.74
580
2401
154
383
4.16
55.68
1.1
1.2
—
—
—
0
0
741
4145
2.00
55.40
2.2
1.7
1170.76
1166.75
nmol/l
0.03
479
3198
1431
9953
1.74
52.64
8.8
8.1
1.14
1.21
inr
2.82
564
2959
3375
30757
3.98
52.60
22.1
9.1
26.55
27.82
u/l
4.07
3344
29826
2866
24336
2.00
52.41
25.5
14.7
13.65
13.56
%
3.21
2845
23816
1810
13503
1.71
51.02
3.9
3.3
0.01
0.00
estimate
0.30
584
2382
1792
13363
1.70
50.33
3.9
3.3
0.00
0.00
estimate
1.08
583
2414
1785
13367
1.69
48.74
5.0
4.4
0.00
0.00
estimate
0.50
596
2491
1118
7540
1.71
44.03
3.7
2.9
—
—
—
0
0
1003
6565
1.74
44.02
4.6
4.3
—
—
—
0
0
177
568
3.23
43.80
1.2
1.2
243.27
263.84
u/ml
0.43
113
360
1643
12337
1.63
42.06
7.1
6.6
1.21
1.21
mmol/l
1.64
1354
10487
147
436
3.48
41.24
1.9
1.5
0.76
0.81
g/l
0.14
109
326
205
760
2.80
39.31
1.4
1.1
—
—
—
0
0
1056
7228
1.66
38.21
4.2
4.0
7.40
7.40
ph
0.25
244
1387
1494
11167
1.59
37.54
6.2
5.9
1.21
1.21
mmol/l
1.58
1375
10177
860
5599
1.71
37.48
1.6
1.4
2.64
2.36
g/l
3.14
604
3590
382
1917
2.11
37.39
3.1
2.8
4.18
4.10
e9/l
0.22
286
1566
181
663
2.82
35.48
1.1
1.2
—
—
—
0
0
66
118
5.68
35.33
13.6
25.7
135.64
117.52
ug/l
1.15
59
97
1387
10337
1.57
34.38
3.4
3.1
—
5.70
—
0
10
3166
28815
2.07
34.03
18.3
13.6
139.53
139.68
mmol/l
3.30
3093
28107
3172
28923
2.06
33.39
18.4
13.7
3.92
3.96
mmol/l
18.90
3097
28158
444
2449
1.93
33.19
1.4
1.5
—
—
—
0
0
246
1084
2.37
32.95
1.7
1.5
9.21
23.83
u/ml
0.86
20
23
117
350
3.42
32.41
3.6
3.5
1.19
1.53
%
0.39
91
291
84
200
4.28
32.19
1.5
1.2
298.82
155.88
titre
0.96
34
34
227
985
2.40
31.46
1.2
1.2
—
—
—
0
0
169
663
2.63
28.99
1.9
1.3
5.83
9.53
iu/ml
—
7
12
443
2557
1.84
28.54
2.3
2.1
327.79
372.60
nmol/l
5.56
410
2353
3258
30296
2.14
27.87
19.0
11.3
—
—
—
0
0
1302
9995
1.48
25.97
2.0
1.9
96.00
96.58
pmol/l
0.17
761
5338
565
3604
1.68
25.46
1.3
1.2
—
—
—
0
0
1886
15611
1.45
25.12
5.2
4.6
6.67
6.64
mmol/l
0.21
1764
14518
489
3021
1.72
24.77
3.3
2.7
6.22
7.65
umol/l
1.57
429
2632
58
135
4.35
22.95
1.1
1.1
1436.64
1485.08
miu/ml
0.11
58
135
3403
32504
2.90
22.81
34.2
17.8
269.81
252.53
e9/l
37.75
3377
31783
50
104
4.86
22.69
1.6
1.7
—
—
—
0
0
30
37
8.17
22.63
2.0
2.1
—
—
—
0
0
412
2487
1.74
22.56
3.1
2.4
37.31
57.23
u/l
0.52
355
2146
3404
32531
2.90
22.55
34.0
17.7
91.67
90.56
fl
38.16
3390
32150
3404
32532
2.90
22.53
34.0
17.7
30.47
30.26
pg
9.82
3390
32148
3404
32537
2.90
22.43
34.1
17.8
4.50
4.57
e12/l
14.38
3372
31746
3404
32545
2.89
22.26
34.2
17.8
6.76
6.69
e9/l
0.99
3371
31750
69
187
3.74
22.23
1.5
1.5
—
—
—
0
0
3404
32547
2.88
22.22
34.3
17.9
136.33
137.61
g/l
6.62
3389
32159
163
753
2.22
19.51
3.1
3.0
—
—
—
0
0
856
6372
1.46
18.69
1.3
1.3
1.13
1.73
u/ml
1.51
239
1786
901
6816
1.43
17.92
4.8
3.8
93.84
92.08
%
1.44
869
6655
165
801
2.11
17.45
5.1
3.6
30.86
5124.02
u/ml
0.86
144
688
2021
17526
1.36
17.28
4.5
3.9
282.57
1519.56
e6/l
1.68
23
229
116
494
2.39
16.82
1.3
1.2
80.00
366.00
titre
—
5
10
441
2973
1.55
15.32
21.8
21.2
1.25
1.27
inr
0.12
89
421
208
1150
1.86
15.18
1.1
1.1
—
—
—
0
0
130
610
2.17
15.03
1.3
1.5
—
—
—
0
0
717
5356
1.43
14.90
2.8
2.5
6.39
5.93
e6/l
0.24
649
4691
64
217
2.99
14.57
3.9
3.7
60.18
55.52
%
0.88
38
153
727
5464
1.42
14.56
1.5
1.5
21.07
20.20
nmol/l
0.79
641
4786
314
1976
1.65
14.54
3.9
3.5
1.23
1.23
mmol/l
0.12
285
1718
94
390
2.45
14.47
1.1
1.1
1.50
1.47
g/l
0.19
85
352
981
7788
1.36
14.05
3.3
3.1
65.99
94.38
e6/l
0.39
800
5931
903
7101
1.37
13.67
3.3
3.0
0.44
0.41
e6/l
0.17
722
5298
118
562
2.14
13.18
1.3
1.5
101.57
119.06
u/ml
1.03
28
113
1130
9246
1.33
13.01
3.7
3.5
86.69
86.30
e6/l
0.00
862
6420
72
282
2.59
12.55
1.3
1.3
—
—
—
0
0
515
3731
1.45
12.46
2.2
2.0
—
—
—
0
0
17
7
24.38
12.45
1.1
1.0
45.08
—
u/ml
—
5
0
377
2570
1.52
12.35
3.4
2.7
1.82
1.78
%
0.31
335
2295
191
1097
1.78
12.34
1.3
1.2
0.20
0.82
u/ml
1.60
11
102
343
2303
1.54
12.05
4.0
4.2
5.58
19.57
ug/l
2.19
262
1844
882
7031
1.34
11.95
3.1
2.9
—
—
—
0
0
653
4968
1.39
11.92
3.0
2.7
566.34
557.16
mosm/kgh2o
0.44
585
4220
70
280
2.53
11.71
1.3
1.3
0.33
0.37
g/l
0.56
40
193
555
4119
1.41
11.70
3.5
3.4
0.81
0.82
mmol/l
1.98
515
3885
70
281
2.52
11.63
1.3
1.3
2.76
3.04
g/l
0.54
41
196
70
281
2.52
11.63
1.3
1.3
7.82
6.78
g/l
1.03
41
195
287
1868
1.58
11.55
3.1
2.8
74.88
71.53
e9/l
0.71
227
1399
1153
9634
1.29
10.95
3.5
3.2
49.96
48.79
ng/l
0.03
728
5916
118
611
1.96
10.57
2.5
3.2
23.89
24.86
mmol/l
1.80
100
535
783
6235
1.33
10.50
1.8
1.7
1.21
1.05
mg/l
0.99
598
4646
104
518
2.04
10.39
2.3
2.5
16.87
16.56
%
0.28
55
266
107
539
2.02
10.37
3.5
3.7
—
—
—
0
0
443
3228
1.43
10.29
6.3
6.2
1.00
1.03
mmol/l
1.81
415
3020
93
451
2.09
10.00
4.0
3.5
63.28
957.14
u/ml
0.94
82
423
431
3148
1.42
9.87
8.8
7.2
104.73
104.41
mmol/l
0.93
426
3080
597
4629
1.35
9.49
1.3
1.3
5.03
10.67
u/ml
2.91
219
1913
106
550
1.96
9.48
3.7
4.1
2.50
2.44
mmol/l
0.09
66
350
625
4885
1.34
9.41
1.3
1.3
13.71
29.22
iu/ml
13.19
180
1506
121
661
1.86
9.27
3.8
4.0
7.42
7.42
ph
0.41
103
540
2227
20379
1.26
9.21
3.8
3.0
50.36
45.54
u/l
1.65
2099
19311
848
6956
1.29
8.95
3.1
2.7
—
—
—
0
0
12
6
20.06
8.46
1.2
1.0
—
—
—
0
0
118
660
1.82
8.42
1.6
1.4
303.37
297.78
ug/g
0.11
71
365
1000
8431
1.26
8.34
3.6
3.3
2.35
2.35
mmol/l
0.34
900
7512
141
837
1.71
8.21
1.5
1.7
0.22
0.24
g/l
1.53
133
793
146
875
1.70
8.21
1.5
1.7
1.17
1.17
g/l
0.11
138
828
47
188
2.52
7.98
1.1
1.0
—
—
—
0
0
28
85
3.31
7.78
1.1
1.3
—
—
—
0
0
853
7107
1.27
7.78
3.4
3.4
—
—
—
0
0
77
388
2.01
7.56
1.9
2.2
6.56
5.72
umol/l
0.29
48
283
48
201
2.41
7.42
1.1
1.1
—
—
—
0
0
308
2232
1.42
7.35
1.4
1.4
—
—
—
0
0
2341
21774
1.23
7.29
3.6
3.8
14.77
14.60
pmol/l
2.93
2158
20071
421
3219
1.35
7.25
1.7
1.7
—
—
—
0
0
448
3475
1.33
7.00
1.2
1.2
—
—
—
0
0
2868
27329
1.28
6.94
21.0
12.9
40.22
40.59
%
1.57
2056
21222
81
430
1.90
6.87
1.5
1.4
—
—
—
0
0
1450
12922
1.21
6.81
4.9
3.9
—
—
—
0
0
53
244
2.19
6.62
4.4
4.4
—
—
—
0
0
93
525
1.79
6.52
2.5
2.8
8.39
8.16
kpa
0.74
83
484
15
33
4.56
6.45
1.5
1.5
—
—
—
0
0
121
741
1.66
6.35
3.1
3.1
1.34
1.47
mg/l
1.10
108
693
731
6109
1.25
6.34
3.6
3.3
—
—
—
0
0
747
6280
1.24
6.12
3.1
2.9
1118.85
1206.88
ng/l
0.29
634
5268
78
432
1.82
5.86
2.7
2.8
—
—
—
0
0
314
2385
1.35
5.65
4.6
4.1
—
—
—
0
0
293
2207
1.36
5.57
8.7
8.1
8.69
9.14
mmol/l
0.58
274
2129
888
7674
1.21
5.49
2.3
2.1
255.62
233.36
u/l
0.10
838
7260
50
245
2.06
5.40
1.0
1.1
278.09
285.45
mg/l
0.28
43
223
2724
25998
1.22
5.37
4.3
4.5
1.70
2.01
mu/l
3.03
2543
24163
212
1530
1.41
5.23
3.3
3.5
5.06
5.16
kpa
1.53
198
1426
278
2098
1.35
5.23
3.6
3.2
—
—
—
0
0
412
3293
1.28
5.15
1.6
1.4
—
—
—
0
0
209
1514
1.40
5.06
3.3
3.5
7.41
7.41
ph
0.12
38
192
85
507
1.69
5.01
1.1
1.1
—
—
—
0
0
158
1097
1.46
4.83
1.2
1.2
—
—
—
0
0
151
1040
1.47
4.81
1.8
1.8
1.54
1.51
g/l
0.12
137
917
967
8523
1.19
4.71
2.7
2.3
—
—
—
0
0
166
1173
1.44
4.64
3.7
3.1
—
—
—
0
0
209
1543
1.38
4.55
6.8
7.1
24.59
24.52
mmol/l
0.10
196
1435
286
2219
1.31
4.48
4.5
3.8
2.12
1.98
mmol/l
0.24
228
1795
28
117
2.40
4.47
1.7
1.5
2.83
4.80
%
—
6
25
114
757
1.52
4.37
1.8
2.1
10.58
10.77
mg/l
0.07
105
706
517
4331
1.23
4.29
2.7
2.6
0.81
1.06
e6/l
1.13
310
2409
135
934
1.46
4.25
2.0
2.1
11.30
1.95
ug/l
0.46
127
837
48
255
1.89
4.20
2.0
2.7
1.34
1.15
e9/l
0.37
22
148
675
5820
1.20
4.16
3.9
3.6
1.02
1.02
kg/l
0.35
86
800
205
1532
1.36
4.16
2.4
2.3
—
—
—
0
0
115
776
1.50
4.11
5.7
5.9
1.22
1.28
mmol/l
0.46
105
668
59
339
1.75
4.04
1.3
1.3
26.36
49.59
u/ml
—
8
19
212
1603
1.34
4.00
5.0
4.9
—
—
—
0
0
243
1879
1.32
3.93
2.4
2.6
68.01
66.88
g/l
1.50
226
1743
51
288
1.78
3.73
1.9
1.7
43.38
58.46
%
1.58
32
179
81
1235
0.65
3.70
1.3
2.4
—
—
—
0
0
78
495
1.59
3.70
3.8
3.7
—
—
—
0
0
96
641
1.51
3.64
3.5
3.5
1.56
2.55
ratio
0.50
15
55
567
4876
1.19
3.58
3.1
3.4
640.77
492.97
ng/l
0.23
385
3482
279
2227
1.27
3.57
4.7
3.8
5.87
5.88
kpa
0.11
267
2158
17
63
2.71
3.48
1.0
1.1
—
—
—
0
0
35
179
1.96
3.48
2.1
2.9
0.19
0.22
e9/l
0.38
28
161
71
448
1.60
3.47
2.1
1.6
—
—
—
0
0
36
187
1.93
3.43
2.2
2.8
562.48
552.69
e6/l
0.03
29
162
43
237
1.82
3.42
2.0
2.5
44.89
43.29
%
—
9
35
113
796
1.43
3.31
1.3
1.2
46.07
42.72
u/ml
—
7
47
9
255
0.35
3.29
16.3
18.1
1297.67
1440.06
nmol/l
—
9
248
96
658
1.47
3.25
3.6
3.5
45.86
65.43
mg/l
0.86
72
531
86
578
1.50
3.21
2.2
2.0
—
—
—
0
0
69
442
1.57
3.20
1.5
1.6
—
—
—
0
0
9
252
0.36
3.15
15.4
13.2
674.67
824.06
nmol/l
—
9
243
9
20
4.51
3.11
1.0
1.0
—
—
—
0
0
288
2349
1.25
3.10
8.8
8.6
122.16
123.78
g/l
0.66
280
2260
12
39
3.08
3.09
1.7
1.8
—
—
—
0
0
131
961
1.38
3.07
5.6
5.2
0.99
0.90
%
1.59
124
894
234
1866
1.27
3.05
1.3
1.3
152.32
199.38
u/ml
0.88
221
1731
107
759
1.42
3.05
3.6
4.4
3.86
3.91
mmol/l
0.73
102
715
95
660
1.45
3.03
3.6
3.5
39.73
65.29
mg/l
0.61
72
534
7
12
5.84
3.02
1.0
1.0
—
—
—
0
0
172
2217
0.76
2.99
1.4
1.4
—
—
—
0
0
82
556
1.49
2.96
2.5
2.3
131.32
131.77
g/l
0.06
72
410
305
2519
1.23
2.94
8.6
8.2
96.83
95.77
%
3.96
293
2431
210
1664
1.28
2.90
2.9
2.5
—
—
—
0
0
146
1101
1.34
2.89
4.8
3.3
25.04
25.36
mmol/l
0.49
140
1066
156
1189
1.33
2.87
1.8
1.8
—
—
—
0
0
471
4063
1.18
2.87
2.9
2.8
2.63
2.45
e6/l
0.15
263
2154
87
602
1.46
2.85
1.3
1.2
29.51
41.06
u/ml
—
9
60
27
136
1.99
2.85
1.2
1.1
149.05
189.70
iu/ml
0.54
27
136
103
736
1.41
2.84
1.3
1.2
11.89
5.63
u/ml
0.83
21
114
130
966
1.36
2.84
5.6
5.1
1.59
1.68
%
0.64
124
896
82
563
1.47
2.80
1.1
1.1
—
—
—
0
0
277
2277
1.24
2.80
1.1
1.2
—
—
—
0
0
108
1472
0.73
2.77
1.3
2.4
—
—
—
0
0
82
565
1.46
2.75
1.1
1.1
—
—
—
0
0
25
124
2.02
2.75
1.2
1.1
—
—
—
0
0
101
724
1.41
2.75
1.3
1.2
9.22
7.12
u/ml
0.13
17
76
203
1614
1.27
2.74
1.4
1.3
27.18
26.18
iu/l
0.16
172
1376
75
509
1.48
2.72
1.1
1.1
—
—
—
0
0
411
3529
1.19
2.66
1.5
1.4
—
—
—
0
0
21
99
2.13
2.64
3.3
2.9
—
—
—
0
0
21
100
2.11
2.58
1.0
1.1
—
—
—
0
0
131
991
1.33
2.57
5.0
4.7
—
—
—
0
0
22
108
2.04
2.51
4.1
5.1
—
—
—
0
0
23
115
2.01
2.50
1.1
1.1
—
—
—
0
0
39
232
1.69
2.48
1.7
1.5
35.90
33.83
%
0.10
20
148
720
6495
1.14
2.41
2.7
2.2
—
—
—
0
0
212
1725
1.24
2.39
3.9
4.1
92.04
88.57
ng/l
0.16
189
1538
792
7199
1.13
2.35
2.6
2.5
3390.42
3683.32
umol/l
0.08
699
6377
76
1058
0.71
2.28
1.5
3.4
—
—
—
0
0
330
2821
1.19
2.27
8.2
7.8
1.06
1.06
mmol/l
0.00
260
2196
66
455
1.46
2.27
3.3
3.0
—
—
—
0
0
123
1589
0.77
2.24
1.3
2.3
—
—
—
0
0
122
1575
0.77
2.22
1.3
2.4
—
—
—
0
0
123
1583
0.77
2.19
1.3
2.2
—
—
—
0
0
246
2058
1.21
2.15
9.8
9.0
—
—
—
0
0
242
2022
1.21
2.14
2.8
2.2
5.03
7.97
ug/l
3.12
218
1821
105
793
1.33
2.14
2.0
2.3
11.74
10.43
g/l
1.19
88
689
329
2829
1.18
2.13
8.2
7.8
5.05
5.13
kpa
0.73
313
2708
106
803
1.33
2.12
1.2
1.1
—
—
—
0
0
329
2830
1.18
2.12
8.2
7.8
12.74
12.62
kpa
0.17
314
2707
31
182
1.71
2.11
1.0
1.2
—
—
—
0
0
2012
19298
1.10
2.10
3.6
3.4
—
—
—
0
0
46
690
0.66
2.08
1.5
3.2
—
—
—
0
0
90
675
1.34
1.95
1.8
2.2
38.84
37.93
g/l
0.79
75
598
69
496
1.40
1.94
1.1
1.2
—
—
—
0
0
55
784
0.70
1.93
1.6
1.5
—
—
—
0
0
123
1555
0.78
1.93
1.3
2.3
—
—
—
0
0
443
3930
1.15
1.92
2.7
2.2
29.99
29.77
s
0.33
426
3814
47
315
1.50
1.90
4.1
2.5
—
—
—
0
0
38
243
1.57
1.89
4.5
3.3
—
—
—
0
0
216
1813
1.20
1.86
4.3
3.0
4.29
4.65
kpa
2.08
207
1749
15
72
2.09
1.86
1.0
1.2
—
—
—
0
0
6
17
3.53
1.83
1.0
1.1
—
—
—
0
0
54
763
0.70
1.82
1.5
1.4
—
—
—
0
0
21
115
1.83
1.82
1.0
1.0
—
—
—
0
0
75
554
1.36
1.81
4.7
3.9
—
—
—
0
0
39
254
1.54
1.81
2.7
2.5
—
—
—
0
0
16
80
2.00
1.79
1.1
1.0
—
—
—
0
0
54
760
0.71
1.79
1.5
1.4
—
—
—
0
0
16
81
1.98
1.74
3.2
3.2
—
—
—
0
0
25
148
1.69
1.70
2.0
2.9
1288.40
1061.11
u/ml
0.26
25
148
176
2101
0.83
1.66
1.2
1.2
91.06
161.41
iu/ml
2.20
64
801
8
31
2.58
1.66
3.4
2.0
123.00
144.29
ng/l
—
8
31
31
196
1.59
1.65
1.8
2.2
12.71
13.92
%
0.15
14
88
33
212
1.56
1.65
1.3
1.1
—
—
—
0
0
482
4349
1.13
1.63
3.0
2.9
2.45
2.44
mmol/l
1.26
420
3825
15
77
1.95
1.59
1.2
1.3
114.12
152.90
nmol/l
—
10
57
62
456
1.37
1.58
1.2
1.2
—
—
—
0
0
2618
25569
1.10
1.57
26.7
15.3
332.31
333.37
g/l
7.77
2609
25383
11
50
2.20
1.57
1.0
1.2
—
—
—
0
0
11
50
2.20
1.57
1.0
1.2
—
—
—
0
0
11
50
2.20
1.57
1.0
1.2
—
—
—
0
0
46
322
1.43
1.55
1.6
1.4
54.43
55.72
mu/l
0.02
37
290
159
1324
1.21
1.54
2.3
2.3
7761.70
5407.93
u/l
0.35
54
523
293
2570
1.15
1.53
2.2
2.3
12.90
13.14
nmol/l
0.20
261
2300
175
1472
1.20
1.52
4.9
3.1
130.70
131.11
g/l
0.08
168
1433
0
43
0.00
1.52
0.0
1.5
—
—
—
0
0
33
217
1.53
1.51
2.2
2.8
914.63
722.33
e6/l
0.57
19
88
30
193
1.56
1.51
1.1
1.1
1.03
1.05
ratio
0.74
16
73
31
201
1.55
1.51
2.1
1.5
—
—
—
0
0
47
333
1.42
1.49
1.3
1.3
—
—
—
0
0
143
1184
1.22
1.47
4.2
4.0
24.20
24.17
mmol/l
0.03
131
1075
17
94
1.81
1.47
2.9
2.5
—
—
—
0
0
77
593
1.31
1.46
1.8
1.7
9216.23
12961.17
e6/l
0.74
57
432
39
268
1.46
1.46
1.1
1.4
—
—
—
0
0
158
1324
1.20
1.45
12.5
10.7
—
—
—
0
0
46
328
1.41
1.42
2.5
1.5
—
—
—
0
0
19
110
1.73
1.42
1.1
1.1
—
—
—
0
0
52
379
1.38
1.42
2.6
2.4
—
—
—
0
0
344
3843
0.88
1.40
1.3
1.3
—
—
—
0
0
7
29
2.42
1.39
1.3
1.3
29.14
959.35
u/l
—
7
23
44
313
1.41
1.39
1.1
1.3
—
—
nmol/l
—
0
0
19
111
1.72
1.39
1.1
1.7
—
—
—
0
0
5
17
2.94
1.36
1.0
1.1
—
—
—
0
0
90
1123
0.80
1.35
1.5
1.4
—
—
—
0
0
251
2202
1.15
1.34
8.7
7.4
1.27
1.36
mmol/l
0.91
240
2120
20
120
1.67
1.34
1.5
1.3
—
—
—
0
0
9
42
2.15
1.33
2.3
3.3
—
29.12
—
0
6
32
216
1.49
1.33
1.2
1.2
—
86.13
—
0
9
95
763
1.25
1.32
1.1
1.1
—
—
—
0
0
50
368
1.36
1.31
1.5
1.4
57.73
64.92
mmol/l
0.62
33
301
42
300
1.40
1.31
1.1
1.1
—
—
—
0
0
9
174
0.52
1.28
1.1
3.2
—
—
—
0
0
81
642
1.27
1.27
1.6
1.3
—
—
—
0
0
21
130
1.62
1.26
1.9
1.6
—
—
—
0
0
7
141
0.50
1.20
2.0
2.5
48.71
53.60
umol/l
—
7
119
26
172
1.52
1.20
3.3
7.0
—
—
—
0
0
131
1102
1.20
1.20
4.6
2.7
0.73
0.66
%
1.27
124
1063
52
392
1.33
1.19
1.3
1.7
—
—
—
0
0
120
1003
1.20
1.18
1.5
1.4
9.47
8.99
u/l
0.17
94
823
26
173
1.51
1.17
1.1
1.2
—
—
—
0
0
48
359
1.34
1.16
1.3
1.2
—
—
—
0
0
0
33
0.00
1.16
0.0
1.0
—
—
—
0
0
0
33
0.00
1.16
0.0
1.2
—
1.81
—
0
33
128
1082
1.19
1.12
2.4
2.1
21.25
21.39
s
0.11
108
938
212
1870
1.14
1.09
2.5
2.7
180.62
171.64
ng/l
0.12
187
1682
13
219
0.59
1.09
1.7
1.5
—
—
—
0
0
100
829
1.21
1.09
1.0
1.1
0.88
4.33
u/ml
—
10
127
29
406
0.71
1.04
4.3
3.7
18.79
26.95
u/ml
0.79
29
395
34
246
1.39
1.03
1.3
1.2
—
—
—
0
0
106
890
1.20
1.02
2.7
2.5
—
—
—
0
0
44
333
1.33
1.01
1.2
1.3
—
—
—
0
0
128
1094
1.18
1.01
3.4
3.5
—
—
—
0
0
18
115
1.57
0.99
1.3
1.2
—
—
—
0
0
28
198
1.42
0.97
1.0
1.0
—
—
—
0
0
7
36
1.95
0.97
1.3
1.3
1.94
1.51
mmol/l
—
7
24
0
31
0.00
0.96
0.0
1.0
—
0.15
—
0
23
75
613
1.23
0.96
1.4
1.5
58.06
127.28
pmol/l
2.34
75
603
0
32
0.00
0.95
0.0
8.6
—
—
—
0
0
35
259
1.35
0.95
1.0
1.1
242.07
281.98
mg/l
1.14
29
223
24
166
1.45
0.94
5.4
3.5
—
—
—
0
0
10
55
1.82
0.92
6.8
6.5
—
—
—
0
0
82
684
1.20
0.88
1.2
1.3
—
—
—
0
0
39
298
1.31
0.87
3.7
2.6
—
—
—
0
0
30
220
1.37
0.87
2.5
2.2
—
—
—
0
0
72
594
1.22
0.87
1.5
2.2
0.93
0.85
nmol/l
0.34
63
505
29
213
1.36
0.84
1.1
1.1
341.12
396.12
nmol/l
0.82
23
194
8
45
1.78
0.84
8.3
7.0
—
—
—
0
0
205
1842
1.12
0.84
1.4
1.4
—
—
—
0
0
30
222
1.35
0.83
1.2
1.2
—
—
—
0
0
19
129
1.48
0.83
1.6
2.8
7.40
7.43
ph
0.61
11
47
13
201
0.65
0.81
1.5
1.5
—
—
—
0
0
24
172
1.40
0.80
1.1
1.1
12.94
10.17
iu/ml
—
5
55
172
1923
0.89
0.79
1.5
1.7
—
—
—
0
0
35
268
1.31
0.79
1.1
1.2
48.08
43.59
mg/l
0.17
29
221
126
1105
1.15
0.77
1.2
1.3
239.99
228.08
miu/ml
0.12
53
529
45
560
0.80
0.76
3.1
3.4
24.00
24.89
mg/l
0.08
29
364
51
413
1.24
0.75
2.2
1.8
—
—
—
0
0
29
218
1.33
0.75
1.2
1.2
—
—
—
0
0
24
175
1.37
0.74
1.9
1.5
6.26
7.32
u/l
0.38
16
149
24
175
1.37
0.74
1.9
2.9
30.43
40.90
%
—
7
52
802
7673
1.06
0.74
4.5
4.0
10.15
9.48
mg/mmol
0.11
538
5002
58
480
1.21
0.71
1.2
1.2
3.52
4.37
u/ml
0.37
29
214
16
109
1.47
0.70
1.0
1.0
—
—
—
0
0
5
26
1.92
0.70
1.6
1.2
—
—
—
0
0
56
674
0.83
0.70
1.6
1.6
—
—
—
0
0
324
3012
1.08
0.69
1.4
1.4
—
—
—
0
0
14
93
1.51
0.69
1.4
1.6
—
—
—
0
0
940
9051
1.05
0.69
4.4
4.3
2.16
2.37
ug/l
0.57
855
8187
55
456
1.21
0.67
1.2
1.5
—
—
—
0
0
27
205
1.32
0.67
1.9
2.4
921.11
624.52
ml
1.35
18
143
25
188
1.33
0.66
1.0
1.0
—
—
—
0
0
16
111
1.44
0.65
1.1
1.2
—
0.12
g/l
—
0
11
762
7308
1.05
0.65
3.6
3.3
215.93
359.19
mg/l
0.59
514
4743
19
137
1.39
0.64
2.4
2.3
24.65
251.72
ug/l
0.67
19
121
66
561
1.18
0.63
2.5
3.1
27.97
36.33
umol/l
3.16
59
488
10
63
1.59
0.61
2.0
2.6
—
—
—
0
0
28
217
1.29
0.61
1.1
1.2
—
—
—
0
0
31
244
1.27
0.61
2.0
2.6
—
—
—
0
0
0
20
0.00
0.60
0.0
3.1
—
—
—
0
0
17
122
1.40
0.60
2.4
2.7
—
—
—
0
0
12
81
1.48
0.57
1.2
1.4
—
—
—
0
0
43
517
0.83
0.56
1.3
1.2
—
—
—
0
0
6
36
1.67
0.56
4.5
3.1
—
—
—
0
0
6
36
1.67
0.56
1.0
1.2
—
—
—
0
0
15
107
1.40
0.55
1.1
1.1
—
—
—
0
0
15
107
1.40
0.55
1.5
2.2
—
—
—
0
0
16
217
0.74
0.55
1.4
1.5
—
—
—
0
0
47
557
0.84
0.54
1.4
1.3
—
—
—
0
0
9
61
1.48
0.53
1.8
2.6
—
—
—
0
0
11
74
1.49
0.53
1.1
1.5
—
—
—
0
0
749
7223
1.05
0.53
1.7
1.6
1.40
1.42
mmol/l
0.28
631
6189
32
259
1.24
0.52
1.3
1.4
13.04
12.48
mmol/l
—
10
57
40
332
1.21
0.52
2.4
2.3
—
—
—
0
0
22
170
1.30
0.51
1.0
1.0
310.94
312.34
ng/l
0.01
17
115
30
242
1.24
0.51
1.2
1.3
1.38
1.50
nmol/l
0.34
25
218
21
162
1.30
0.50
1.2
1.2
—
—
—
0
0
112
1238
0.90
0.49
2.4
2.3
—
—
—
0
0
15
110
1.37
0.48
2.5
2.8
—
—
—
0
0
7
111
0.63
0.48
1.0
1.0
—
—
—
0
0
2759
27338
1.04
0.48
4.2
4.1
5.88
5.86
mmol/l
0.29
2549
25328
7
47
1.49
0.47
2.1
1.4
—
—
—
0
0
57
494
1.16
0.47
1.1
1.1
2.79
1116.85
iu/ml
0.57
12
124
37
309
1.20
0.46
1.4
1.4
375.17
276.44
pmol/l
0.75
29
232
29
236
1.23
0.46
1.4
1.4
2865.88
90764.98
e6/l
1.42
16
168
17
221
0.77
0.46
1.4
1.4
16740.83
82244.17
e6/l
1.54
12
139
45
525
0.86
0.45
1.4
1.2
—
—
—
0
0
15
112
1.34
0.44
1.1
1.2
—
—
—
0
0
170
1829
0.93
0.43
1.3
1.2
—
—
—
0
0
509
5293
0.96
0.43
2.7
2.8
0.75
0.72
ug/l
0.29
322
3210
33
276
1.20
0.42
3.0
5.0
56.77
73.32
u/ml
—
9
80
96
870
1.11
0.42
3.9
3.2
0.42
0.33
g/l
0.29
51
377
21
167
1.26
0.41
1.0
1.0
798.38
751.68
ng/l
0.29
13
111
0
15
0.00
0.41
0.0
1.1
—
0.22
—
0
5
0
15
0.00
0.41
0.0
5.9
—
461.47
—
0
15
15
114
1.32
0.40
1.9
3.2
61.89
130.92
umol/l
—
9
66
100
911
1.10
0.40
8.6
8.9
—
—
—
0
0
12
88
1.36
0.40
2.3
1.7
—
—
—
0
0
21
259
0.81
0.39
2.0
1.4
1.46
1.33
promille
0.13
16
198
51
580
0.88
0.38
1.1
1.1
0.60
2.11
u/ml
—
10
138
25
302
0.83
0.38
1.6
1.6
—
—
—
0
0
8
113
0.71
0.37
1.0
1.1
—
3.80
—
0
17
9
69
1.31
0.37
1.0
1.1
—
—
—
0
0
5
37
1.35
0.37
6.6
9.2
—
—
—
0
0
8
114
0.70
0.37
8.8
5.8
—
—
—
0
0
8
114
0.70
0.37
4.4
2.9
—
—
—
0
0
17
134
1.27
0.36
1.1
1.2
—
—
—
0
0
297
3105
0.95
0.34
4.1
4.1
31.68
31.27
%
0.29
223
2188
40
350
1.14
0.32
2.9
3.1
0.82
0.83
nmol/l
0.06
33
269
2883
29000
0.97
0.32
4.5
4.4
2.76
2.83
mmol/l
2.54
2683
27166
21
251
0.84
0.31
1.1
1.2
—
—
—
0
0
56
620
0.90
0.30
1.1
1.1
5.09
5.79
u/ml
0.09
22
322
18
217
0.83
0.29
1.1
1.3
—
1.53
—
0
12
8
107
0.75
0.29
1.3
1.4
69.50
73.05
%
—
8
102
7
57
1.23
0.29
1.0
1.1
—
—
—
0
0
66
603
1.10
0.28
1.4
1.4
—
—
—
0
0
28
242
1.16
0.28
1.0
1.1
—
—
—
0
0
8
63
1.27
0.27
2.8
2.3
—
—
—
0
0
33
290
1.14
0.27
3.1
3.0
24.76
22.40
nmol/l
0.04
33
282
2595
25781
1.03
0.26
5.5
5.1
39.10
39.11
mmol/mol
0.02
2449
24230
101
945
1.07
0.26
4.0
3.6
24.79
24.82
mmol/l
0.05
93
879
71
655
1.09
0.25
1.1
1.3
3.52
3.75
mmol/l
1.34
64
614
2734
27493
0.97
0.25
3.8
3.7
1.31
1.32
mmol/l
0.21
2551
25708
92
860
1.07
0.24
2.3
2.5
191.84
439.14
ug/l
2.12
84
810
46
507
0.91
0.24
1.0
1.1
1.31
3.82
u/ml
2.05
15
187
26
227
1.15
0.23
1.1
1.1
—
—
—
0
0
25
218
1.15
0.23
1.8
1.9
6.92
6.73
mmol/l
0.12
16
155
2833
28464
0.97
0.23
4.2
4.0
1.46
1.43
mmol/l
2.22
2649
26722
63
681
0.92
0.23
1.1
1.1
2.60
1.37
u/ml
0.37
19
263
22
191
1.15
0.21
1.2
1.2
—
—
—
0
0
854
8400
1.02
0.21
1.6
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
2025.42
—
0
12
8
104
0.77
0.21
1.3
1.4
352.50
428.80
mu/l
—
8
99
0
13
0.00
0.21
0.0
1.0
—
0.18
—
0
7
28
249
1.13
0.20
1.8
1.5
0.89
0.98
g/l
1.02
28
249
14
166
0.84
0.20
1.1
1.3
—
—
—
0
0
58
538
1.08
0.20
1.5
1.4
0.30
0.41
nmol/l
0.78
46
426
6
50
1.20
0.19
1.8
1.2
—
—
—
0
0
39
426
0.91
0.19
1.0
1.0
0.81
0.33
u/ml
—
5
89
6
53
1.13
0.18
1.2
1.1
—
—
—
0
0
43
467
0.92
0.18
1.0
1.1
3.13
4.73
u/ml
0.56
16
187
22
194
1.13
0.18
1.0
1.0
11.54
2.14
u/ml
—
8
53
7
61
1.15
0.17
1.3
1.1
—
—
—
0
0
7
61
1.15
0.17
1.3
1.1
—
—
—
0
0
7
61
1.15
0.17
1.3
1.1
—
—
—
0
0
13
110
1.18
0.17
1.2
1.5
—
—
—
0
0
115
1100
1.05
0.17
1.9
1.7
—
—
—
0
0
67
632
1.06
0.16
2.4
2.5
131.49
123.39
ug/min
0.04
39
398
132
1272
1.04
0.15
1.5
1.6
276.79
291.57
mu/l
0.32
121
1155
9
82
1.10
0.15
1.3
1.1
—
—
—
0
0
828
8182
1.02
0.14
3.4
3.3
8.59
8.06
mmol/l
2.40
707
7019
181
1863
0.97
0.14
1.3
1.3
45.43
52.13
au/ml
—
9
85
15
132
1.14
0.13
2.4
2.0
—
—
—
0
0
69
658
1.05
0.12
1.2
1.4
167.02
29.60
e6/l
0.42
57
507
69
658
1.05
0.12
1.3
1.5
624.39
1330.30
e6/l
0.49
61
533
12
104
1.15
0.12
2.0
1.6
—
—
—
0
0
10
85
1.18
0.12
1.4
1.1
—
—
—
0
0
33
307
1.08
0.12
1.4
1.4
—
—
—
0
0
11
126
0.87
0.11
1.0
1.1
—
6.69
—
0
28
39
414
0.94
0.11
1.4
1.3
6.88
6.98
mmol/l
0.07
28
305
13
115
1.13
0.10
1.9
1.7
—
—
—
0
0
22
202
1.09
0.10
1.0
1.0
0.34
0.77
u/ml
—
8
45
5
45
1.11
0.09
1.0
1.2
—
—
—
0
0
24
223
1.08
0.09
1.3
1.3
0.39
0.79
u/ml
—
8
91
1142
11492
0.99
0.09
2.8
2.6
—
—
—
0
0
18
196
0.92
0.09
1.2
1.2
—
—
—
0
0
182
1784
1.02
0.08
3.4
3.3
4.48
4.52
pmol/l
0.28
165
1599
5
61
0.82
0.08
2.2
2.5
—
—
—
0
0
5
65
0.77
0.08
1.0
1.4
—
—
—
0
0
7
66
1.06
0.08
1.9
1.3
61.57
32.14
%
—
7
44
6
71
0.84
0.07
2.2
2.4
—
—
—
0
0
57
590
0.97
0.07
1.1
1.1
0.60
1.34
u/ml
0.93
17
239
8
92
0.87
0.06
8.5
13.7
—
—
—
0
0
46
443
1.04
0.06
1.1
1.5
—
—
—
0
0
54
558
0.97
0.06
6.0
2.8
—
—
—
0
0
14
129
1.09
0.05
1.2
1.1
—
—
—
0
0
42
405
1.04
0.05
1.4
1.4
—
—
—
0
0
13
120
1.08
0.04
2.4
2.6
—
—
—
0
0
2859
28623
0.99
0.04
4.3
4.1
4.67
4.72
mmol/l
1.82
2682
26991
348
3507
0.99
0.04
1.7
1.7
—
—
—
0
0
28
292
0.96
0.04
1.3
1.4
60.23
166.98
pmol/l
—
8
93
200
2022
0.99
0.04
2.3
2.3
29.77
21.83
au/ml
0.31
14
142
42
433
0.97
0.04
1.1
1.3
2.68
4.05
ug/l
1.16
37
392
343
3405
1.01
0.04
1.6
1.7
—
—
—
0
0
24
251
0.96
0.04
1.5
1.6
7.19
7.59
mmol/l
0.25
14
153
53
517
1.03
0.04
1.3
1.4
27.84
23.87
u/l
0.36
44
426
20
190
1.05
0.04
1.7
2.3
—
—
—
0
0
46
470
0.98
0.02
1.0
1.1
1.92
2.86
u/ml
0.82
17
242
146
1473
0.99
0.02
1.1
1.1
—
—
—
0
0
12
127
0.94
0.01
2.3
2.4
—
—
—
0
0
129
1300
0.99
0.01
12.6
10.4
23.89
24.34
mmol/l
0.94
123
1229
18
187
0.96
0.01
1.7
2.0
1.17
1.93
u/field
0.83
12
88
71
716
0.99
0.00
2.5
2.0
4.07
4.50
iu/l
0.18
29
267
15
152
0.99
0.00
1.1
1.4
140.97
135.20
nmol/l
0.23
15
152
30
298
1.01
0.00
1.7
1.6
—
—
—
0
0
30
298
1.01
0.00
1.7
1.6
—
—
—
0
0
30
298
1.01
0.00
1.7
1.6
—
—
—
0
0
30
298
1.01
0.00
1.7
1.6
—
—
—
0
0
14
135
1.04
0.00
1.4
1.6
—
—
—
0
0
20
201
0.99
0.00
1.1
1.0
—
—
—
0
0
9
92
0.98
0.00
2.1
2.2
—
—
—
0
0
7
70
1.00
0.00
2.1
2.1
14.21
16.23
umol/l
—
7
70
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
191.19
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
2923.32
—
0
5
0
5
0.00
0.00
0.0
3.6
—
1.92
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
54
0.93
0.00
1.4
3.2
—
47.77
—
0
13
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
64.83
—
0
6
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
542.78
—
0
6
5
52
0.96
0.00
1.2
1.4
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
7
75
0.93
0.00
2.1
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
103.66
—
0
5

Mortality – FinRegistry

Association

Association between endpoint ULCERRECT and mortality.

Females

Parameter HR [95% CI] p-value
ULCERRECT 1.163 [1.04, 1.3] 0.008
Birth year 0.996 [0.99, 1.0] 0.309

During the follow-up period (1.1.1998 — 31.12.2019), 677 out of 8056 females with ULCERRECT died.

Males

Parameter HR [95% CI] p-value
ULCERRECT 1.093 [1.0, 1.2] 0.061
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1254 out of 9221 males with ULCERRECT died.

Mortality risk

Mortality risk for people of age

years, who have ULCERRECT.

N-year risk Females Males
1 0.07% 0.233%
5 0.59% 1.167%
10 1.628% 2.921%
15 3.162% 5.473%
20 5.425% 8.891%

Relationships between endpoints

Index endpoint: ULCERRECT – Ulcerative rectosigmoiditis

GWS hits: 18

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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