thrombophilia: A condition characterized by an abnormally high level of thrombi. Causes include thrombotic thrombocytopenic purpura, disseminated intravascular coagulation, bone marrow disorders, and antiphospholipid antibody syndrome.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
2824 |
4. Check minimum number of eventsNone |
2824 |
5. Include endpoints |
2874 |
6. Filter based on genotype QC (FinnGen only) |
2874 |
Control definitions (FinnGen only)
- Control exclude
- D3_COAGDEF_PURPUR_HAEMORRHAGIC
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- D65-D69
- Name in latin
- Aliae defectus coagulationis
Similar endpoints
↥List of similar endpoints to
Other coagulation defects
based on the number of shared cases.
Similar with more cases:
- Coagulation defects, purpura and other haemorrhagic conditions
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 20109 | 12309 | 7658 |
| Only index persons | 17670 | 11271 | 6399 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.30 | 0.35 | 0.21 |
| Only index persons | 0.35 | 0.41 | 0.24 |
| Median age at first event (years) | |||
| Whole population | 47.12 | 40.21 | 58.04 |
| Only index persons | 45.48 | 39.12 | 56.67 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2874 | 1913 | 961 |
| Unadjusted period prevalence (%) | 0.58 | 0.65 | 0.42 |
| Median age at first event (years) | 48.05 | 41.44 | 61.22 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2536
- Matched controls
- 25359
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D68.9
ICD-10 Finland
Coagulation defect, unspecified
1209.0
323.0
407
*
D68.0
ICD-10 Finland
Von Willebrand disease
2415.4
323.0
429
*
B01AB05
ATC
enoxaparin; parenteral
5.6
323.0
1380
4463
D68.3
ICD-10 Finland
Haemorrhagic disorder due to circulating anticoagulants
1355.3
323.0
351
*
D68.8
ICD-10 Finland
Other specified coagulation defects
2271.6
323.0
1319
12
B01AA03
ATC
warfarin; systemic
7.9
323.0
1134
2360
D68.2
ICD-10 Finland
Hereditary deficiency of other clotting factors
851.0
312.4
301
*
B01AB04
ATC
dalteparin; parenteral
9.4
173.1
381
469
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
49.4
151.3
184
40
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
9.8
144.6
308
353
126
Kela drug reimbursment
Chronic coagulation defects
+∞
137.8
131
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
7.5
131.2
332
501
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
4.5
120.3
486
1281
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
11.3
120.3
236
229
379
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the long-term prevention of recurrent deep veinthrombosis and pulmonary embolism
13.8
107.6
191
149
B02AA02
ATC
tranexamic acid; systemic
3.0
85.5
591
2339
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
17.5
76.3
122
73
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
76.2
1127
6684
XF400
NOMESCO Finland
ECG with 12 standard connections
2.9
73.4
528
2119
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
69.1
524
2166
I82.88
ICD-10 Finland
Embolism and thrombosis of other specified veins
10.9
68.6
135
130
N02AX02
ATC
tramadol; systemic, rectal
2.1
68.0
1121
6867
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
76.3
65.4
74
10
R4110
NOMESCO Finland
Physiotherapy
2.2
59.7
751
4020
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
58.6
434
1749
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.7
58.6
276
805
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.0
58.0
369
1349
K94
ICPC
Phlebitis/thrombophlebitis
10.2
57.6
117
120
R06.0
ICD-10 Finland
Dyspnoea
2.2
56.8
687
3596
B01AB10
ATC
tinzaparin; parenteral
3.8
56.6
259
736
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
55.9
602
2976
D69.9
ICD-10 Finland
Haemorrhagic condition, unspecified
79.5
55.2
62
8
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
53.5
755
4216
M79.6
ICD-10 Finland
Pain in limb
2.0
52.7
960
5939
I82.9
ICD-10 Finland
Embolism and thrombosis of unspecified vein
8.6
51.9
116
141
N02BE01
ATC
paracetamol; systemic, rectal
2.2
51.3
2160
18225
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
49.4
734
4160
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.3
48.9
190
464
C03CA01
ATC
furosemide; systemic
2.1
48.5
662
3616
AA1AD
NOMESCO Finland
CT of head and brain
2.2
46.8
600
3180
D68.4
ICD-10 Finland
Acquired coagulation factor deficiency
466.0
46.4
46
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
43.5
768
4615
H02AB06
ATC
prednisolone; systemic
1.8
43.1
1168
8140
I48
ICD-10 Finland
Atrial fibrillation and flutter
2.2
42.9
516
2645
K78
ICPC
Atrial fibrillation/flutter
3.4
42.4
225
716
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
42.1
1170
8200
ZX120
NOMESCO Finland
Intravenous
2.8
40.9
283
1079
I80.0
ICD-10 Finland
Phlebitis and thrombophlebitis of superficial vessels of lower extremities
4.4
40.4
152
359
C07AB07
ATC
bisoprolol; oral
1.8
40.4
1047
7143
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
40.0
966
6431
I26.0
ICD-10 Finland
Pulmonary embolism with mention of acute cor pulmonale
7.1
39.3
99
145
WX892
NOMESCO Finland
Monitored bed care
3.1
38.9
234
814
R04.0
ICD-10 Finland
Epistaxis
3.2
38.6
216
713
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
38.5
632
3665
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
3.2
38.2
215
713
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
3.6
38.1
182
533
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.3
37.6
384
1812
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.0
37.5
572
3220
4511A
ICD-9 Finland
Phlebitis and thrombophlebitis, Of deep vessels of lower extremities
12.5
37.0
67
55
I80.8
ICD-10 Finland
Phlebitis and thrombophlebitis of other sites
7.7
35.6
84
112
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
+∞
35.5
34
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.2
35.2
417
2104
J01DB01
ATC
cefalexin; oral
1.9
35.1
2051
17603
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
3.3
34.8
185
589
K99
ICPC
Cardiovascular disease other
4.9
34.5
116
244
2864A
ICD-9 Finland
Coagulation defects, von Willebrand's disease
+∞
34.4
33
*
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
33.8
915
6229
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
3.1
33.6
199
684
TPH07
NOMESCO Finland
Cathetrisation of artery
2.6
33.5
272
1134
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
8.5
33.5
74
89
R60.0
ICD-10 Finland
Localized oedema
2.5
33.3
286
1232
A02BC02
ATC
pantoprazole; systemic
1.7
32.7
1511
11930
I87.0
ICD-10 Finland
Postthrombotic syndrome
37.9
32.5
41
11
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.5
32.2
265
1115
I80.9
ICD-10 Finland
Phlebitis and thrombophlebitis of unspecified site
6.9
32.1
82
123
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
32.0
352
1713
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.6
31.6
249
1020
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
2.5
31.6
270
1159
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
11.2
31.0
59
54
WX002
NOMESCO Finland
Sedation and analgesia
1.9
30.2
477
2693
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
3.5
29.6
145
433
H02AB07
ATC
prednisone; oral
2.1
28.9
376
1962
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
13.0
28.9
51
40
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.9
28.7
180
641
D66
ICD-10 Finland
Hereditary factor VIII deficiency
+∞
28.2
27
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
28.0
295
1400
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
27.9
330
1653
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
27.7
799
5463
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.9
27.7
174
621
R51.80
ICD-10 Finland
Headache
2.0
27.6
411
2261
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.8
27.5
609
3846
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
27.2
587
3678
Z71.8
ICD-10 Finland
Other specified counselling
1.7
27.0
627
4013
I80.20
ICD-10 Finland
Phlebitis and thrombophlebitis in the iliac vein
20.3
26.9
40
20
N03AX16
ATC
pregabalin; oral
1.8
26.9
555
3422
B01AX05
ATC
fondaparinux; parenteral
10.8
26.5
51
48
J01MA02
ATC
ciprofloxacin; systemic
1.6
26.5
887
6299
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.5
26.3
219
922
K93
ICPC
Pulmonary embolism
8.9
25.7
55
63
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
25.5
450
2628
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.4
25.2
233
1038
28630
ICD-8 Finland
Coagulation defects, Vascular haemophilia
+∞
25.0
24
*
EBA10
NOMESCO Finland
Surgical removal of tooth
2.0
24.9
347
1853
UJF32
NOMESCO Finland
Coloscopy
1.7
24.8
572
3642
L04AX01
ATC
azathioprine; systemic
3.1
24.7
140
466
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.8
24.5
518
3208
R4120
NOMESCO Finland
Occupational therapy
2.6
24.2
182
725
R50.9
ICD-10 Finland
Fever, unspecified
2.0
23.9
349
1898
J45.9
ICD-10 Finland
Asthma, unspecified
1.8
23.8
433
2551
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
23.8
649
4332
L17
ICPC
Foot/toe symptom/complaint
1.7
23.5
582
3776
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
22.9
516
3250
I50.9
ICD-10 Finland
Heart failure, unspecified
2.1
22.8
271
1355
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.8
22.7
416
2452
A46
ICD-10 Finland
Erysipelas
2.0
22.4
301
1585
I26
ICD-10 Finland
Pulmonary embolism
8.4
22.4
49
59
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
6.0
22.2
62
106
J01MA12
ATC
levofloxacin; systemic
1.8
22.1
409
2414
ZXA00
NOMESCO Finland
Right side
1.7
22.1
589
3891
XF404
NOMESCO Finland
Ambulatory ECG
2.2
21.7
227
1070
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
21.7
435
2635
R03AC02
ATC
salbutamol; inhalant
1.5
21.5
1260
10059
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
21.5
128
440
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
5.9
21.0
59
102
XA800
NOMESCO Finland
Neuropsychological investigation
3.0
20.9
126
438
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
20.7
264
1359
O28.0
ICD-10 Finland
Abnormal haematological finding on antenatal screening of mother
30.3
20.6
27
9
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.0
20.3
259
1333
J01FF01
ATC
clindamycin; systemic
1.6
20.1
631
4339
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
20.1
1215
9710
O22.3
ICD-10 Finland
Deep phlebothrombosis in pregnancy
17.4
20.0
31
18
A02BC01
ATC
omeprazole; systemic
1.6
20.0
625
4296
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
19.7
552
3679
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
6.9
19.7
49
72
D69.1
ICD-10 Finland
Qualitative platelet defects
201.5
19.6
20
*
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
19.5
150
607
J01DA01
ATC
[U] cefalexin; systemic
1.5
19.4
1479
12366
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
19.2
717
5138
R79.9
ICD-10 Finland
Abnormal finding of blood chemistry, unspecified
9.9
19.1
38
39
3AC01
NOMESCO Finland
NA
6.1
19.1
52
87
D69.0
ICD-10 Finland
Allergic purpura
55.4
18.9
22
*
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
3.7
18.9
84
234
L04AA06
ATC
mycophenolic acid; systemic
4.6
18.8
66
148
WX402
NOMESCO Finland
General anaesthesia
1.7
18.7
391
2392
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.9
18.6
117
419
K92.1
ICD-10 Finland
Melaena
2.7
18.6
127
480
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.0
18.5
241
1249
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
4.9
18.4
60
124
A02BC05
ATC
esomeprazole; systemic
1.5
18.3
888
6731
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
1.9
18.2
298
1683
P01BA02
ATC
hydroxychloroquine; oral
2.1
18.1
207
1018
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
18.0
726
5276
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
18.0
697
5022
ZXA10
NOMESCO Finland
Bilateral
1.7
17.9
407
2554
Z01.7
ICD-10 Finland
Laboratory examination
1.9
17.8
268
1467
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
17.8
183
857
B01AF01
ATC
rivaroxaban; oral
2.0
17.8
242
1276
ZXA05
NOMESCO Finland
Left side
1.6
17.7
536
3633
M32.0
ICD-10 Finland
Drug-induced systemic lupus erythematosus
22.9
17.7
25
11
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
17.7
112
403
UJF30
NOMESCO Finland
Ileoscopy through colon
2.0
17.7
225
1155
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
8.6
17.7
38
45
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
17.6
401
2514
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.2
17.5
182
856
D64.9
ICD-10 Finland
Anaemia, unspecified
2.1
17.5
211
1057
D68
ICD-10 Finland
Other coagulation defects
181.2
17.5
18
*
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
17.4
404
2547
M32.1
ICD-10 Finland
Systemic lupus erythematosus with organ or system involvement
21.0
17.3
25
12
I50.0
ICD-10 Finland
Congestive heart failure
2.4
17.2
150
648
R06AE07
ATC
cetirizine; oral
1.4
16.9
1031
8149
R42
ICD-10 Finland
Dizziness and giddiness
1.6
16.9
465
3074
M25.5
ICD-10 Finland
Pain in joint
1.5
16.9
644
4613
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
16.9
177
836
N02AA05
ATC
oxycodone; systemic
1.8
16.8
292
1681
R03BA02
ATC
budesonide; inhalant
1.7
16.8
413
2645
JN4BD
NOMESCO Finland
Extensive body CT
2.0
16.7
226
1187
28698
ICD-8 Finland
Coagulation defects, Other
+∞
16.7
16
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.2
16.7
169
787
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.9
16.6
254
1399
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
16.5
397
2528
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
4.9
16.4
53
109
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.1
16.4
90
296
45100
ICD-8 Finland
Phlebitis and thrombophlebitis, Of lower extremities
8.1
16.3
36
45
M01AG02
ATC
tolfenamic acid; oral, rectal
1.7
16.1
385
2447
B01AF02
ATC
apixaban; oral
2.1
16.0
185
914
L28
ICPC
Limited function/disability (L)
1.7
16.0
324
1961
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
15.9
1823
20075
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
15.9
147
653
E0000UV
ATC
NA
1.4
15.9
901
7001
I80
ICD-10 Finland
Phlebitis and thrombophlebitis
5.7
15.9
45
80
TFP20
NOMESCO Finland
Cardiodefibrillation
2.3
15.8
152
688
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.0
15.8
93
321
SPAT1229
SPAT
Assessment of need for aid
2.2
15.8
167
793
J01MA14
ATC
moxifloxacin; systemic
2.0
15.7
206
1068
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.4
15.6
76
229
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
15.5
1078
8696
Z31.5
ICD-10 Finland
Genetic counselling
2.3
15.4
147
663
J45.1
ICD-10 Finland
Nonallergic asthma
2.1
15.4
169
815
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
15.3
361
2279
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
15.3
215
1145
R55
ICD-10 Finland
Syncope and collapse
1.9
15.3
231
1267
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
15.1
242
1352
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.1
15.0
169
826
O36.4
ICD-10 Finland
Maternal care for intrauterine death
9.0
14.9
31
35
WX110
NOMESCO Finland
Local anesthesy
1.4
14.9
1624
14155
TK800
NOMESCO Finland
Hemodialysis
4.0
14.9
59
150
K22
ICPC
Risk factor cardiovascular disease
2.6
14.8
112
450
315
Kela drug reimbursment
Clopidogrel
5.9
14.8
41
71
J01FA06
ATC
roxithromycin; oral
1.4
14.8
909
7142
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.9
14.7
59
152
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
14.6
125
534
129
Kela drug reimbursment
Idiopathic thrombocytopaenia or granulocytopenia
80.6
14.6
16
*
PG9AC
NOMESCO Finland
Arteriography with X-ray not elsewhere classified
8.5
14.5
31
37
XF600
NOMESCO Finland
Bloodpressure measurement
2.2
14.4
150
707
R23.3
ICD-10 Finland
Spontaneous ecchymoses
3.9
14.4
59
155
W19
ICD-10 Finland
Unspecified fall
1.9
14.4
206
1108
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.1
14.3
168
833
C01CA24
ATC
epinephrine; parenteral
2.1
14.3
161
786
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.7
14.3
61
166
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
2.9
14.3
87
306
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.2
14.3
156
750
M04AA01
ATC
allopurinol; systemic
1.8
14.2
235
1327
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
14.2
249
1433
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.8
14.2
261
1527
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.2
14.2
75
241
J01FA10
ATC
azithromycin; systemic
1.4
14.1
1367
11612
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
14.0
280
1683
L14
ICPC
Leg/thigh symptom/complaint
2.1
14.0
166
828
A01
ICPC
Pain general/multiple sites
2.1
14.0
170
856
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.8
14.0
252
1465
N03AX12
ATC
gabapentin; oral
1.7
13.9
321
2012
N30.0
ICD-10 Finland
Acute cystitis
1.7
13.8
317
1984
J01AA02
ATC
doxycycline; systemic
1.4
13.8
1784
15908
M05BA04
ATC
alendronic acid; oral
2.1
13.8
158
779
R03DC03
ATC
montelukast; oral
1.6
13.7
377
2479
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.0
13.7
179
929
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.9
13.7
197
1060
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.5
13.7
107
437
WW500
NOMESCO Finland
Blood transfusion
2.6
13.6
96
371
2BD06
NOMESCO Finland
NA
+∞
13.5
13
*
D68.1
ICD-10 Finland
Hereditary factor XI deficiency
+∞
13.5
13
*
R31
ICD-10 Finland
Unspecified haematuria
1.9
13.5
201
1093
A11CC03
ATC
alfacalcidol; systemic
3.6
13.4
59
165
XF402
NOMESCO Finland
ECG with work load test
1.9
13.3
213
1191
H02AB04
ATC
methylprednisolone; systemic
1.7
13.2
322
2049
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.9
13.2
197
1075
S16
ICPC
Bruise/contusion
2.9
13.2
81
287
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.6
13.2
325
2077
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
3.1
13.1
73
244
M32.8
ICD-10 Finland
Other forms of systemic lupus erythematosus
15.1
13.1
21
14
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.3
12.9
125
569
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.6
12.9
57
160
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.7
12.9
56
155
R53
ICD-10 Finland
Malaise and fatigue
1.5
12.8
454
3171
B83
ICPC
Purpura/coagulation defect
50.2
12.8
15
*
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
12.8
415
2838
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
12.8
174
916
G43.9
ICD-10 Finland
Migraine, unspecified
2.0
12.8
161
821
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
3.0
12.8
73
246
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
12.7
374
2497
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
3.1
12.7
68
221
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
12.7
371
2475
N05CF01
ATC
zopiclone; oral
1.4
12.7
654
4940
XW000
NOMESCO Finland
Bone marrow biopsy
2.7
12.6
88
339
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.1
12.5
68
224
B02BD02
ATC
coagulation factor VIII; parenteral, topical, urethral
+∞
12.5
12
*
G47.3
ICD-10 Finland
Sleep apnoea
1.5
12.5
408
2795
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.4
12.4
59
176
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
1.9
12.4
179
966
R07.3
ICD-10 Finland
Other chest pain
1.9
12.4
194
1077
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.4
12.4
102
430
L04AD01
ATC
ciclosporin; systemic
3.6
12.3
55
156
XF620
NOMESCO Finland
Examination of circulation with color method
8.0
12.3
27
34
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
3.0
12.3
68
227
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.8
12.2
200
1126
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
12.2
832
6601
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.9
12.2
187
1031
P01AB01
ATC
metronidazole; oral, rectal
1.4
12.2
884
7091
R20.2
ICD-10 Finland
Paraesthesia of skin
2.0
12.1
158
819
127
Kela drug reimbursment
Transplant complication
4.2
12.1
45
109
R21
ICD-10 Finland
Rash and other nonspecific skin eruption
2.4
12.1
100
422
R06AX27
ATC
desloratadine; oral
1.4
12.1
631
4773
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
12.1
434
3037
X58
ICD-10 Finland
Exposure to other specified factors
1.6
12.1
292
1854
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
12.0
896
7216
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
3.1
12.0
64
208
JN3AD
NOMESCO Finland
Abdominal CT examination
2.0
12.0
161
844
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
1.6
11.9
371
2510
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
11.8
191
1073
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.3
11.8
104
455
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
11.7
350
2345
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
11.7
211
1228
J01CA04
ATC
amoxicillin; systemic
1.4
11.6
1938
17713
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.9
11.6
170
922
C03DA01
ATC
spironolactone; oral
1.8
11.6
205
1185
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
4.4
11.6
41
95
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.3
11.6
106
473
R02
ICPC
Shortness of breath/dyspnoea
1.7
11.5
247
1517
C01AA05
ATC
digoxin; systemic
2.0
11.5
147
756
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
5.9
11.5
31
53
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.0
11.5
153
799
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
1.8
11.5
218
1288
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.1
11.4
131
646
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.0
11.3
150
781
K90
ICPC
Stroke/cerebrovascular accident
3.0
11.3
63
212
WX722
NOMESCO Finland
PEEP
2.3
11.3
104
465
N96
ICD-10 Finland
Habitual aborter
4.9
11.3
36
75
H02AB09
ATC
hydrocortisone; systemic
3.0
11.3
62
207
R01AD09
ATC
mometasone; nasal
1.3
11.3
1021
8464
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.6
11.2
82
325
M03BX02
ATC
tizanidine; oral
1.3
11.2
1391
12090
205
Kela drug reimbursment
Chronic hypertension
1.5
11.1
494
3615
S97
ICPC
Chronic ulcer skin
2.2
11.1
110
509
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
4.0
11.1
43
109
Z32.1
ICD-10 Finland
Pregnancy confirmed
1.7
11.1
249
1546
A06AC01
ATC
ispaghula (psylla seeds); oral
1.5
11.0
479
3485
A08
ICPC
Swelling
2.4
11.0
94
405
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
11.0
122
593
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.8
11.0
180
1013
6BA02
NOMESCO Finland
NA
13.9
11.0
18
13
K92.0
ICD-10 Finland
Haematemesis
3.2
10.9
56
178
J01MA06
ATC
norfloxacin; oral
1.6
10.8
290
1888
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
3.2
10.8
55
174
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
10.8
133
674
S06.0
ICD-10 Finland
Concussion
1.7
10.8
230
1407
2BD01
NOMESCO Finland
NA
17.9
10.7
16
9
C10AA05
ATC
atorvastatin; oral
1.4
10.7
656
5088
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
10.7
236
1460
PD5BD
NOMESCO Finland
Extensive CT of aorta
3.6
10.7
46
128
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.7
10.7
231
1423
A02BA02
ATC
ranitidine; systemic
1.5
10.6
390
2738
LCA06
NOMESCO Finland
Biopsy of endometrium
1.6
10.6
267
1711
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
10.6
130
658
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
4.8
10.5
34
72
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
2.5
10.5
84
349
S18
ICPC
Laceration/cut
1.4
10.5
831
6723
C09AA05
ATC
ramipril; oral
1.5
10.5
434
3122
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
3.2
10.5
53
167
I81
ICD-10 Finland
Portal vein thrombosis
9.2
10.5
21
23
B99
ICPC
Blood/lymph/spleen disease other
7.3
10.5
24
33
194
Kela drug reimbursment
Blood coagulation factor VIII and von Willebrand factor for the treatment of von Willebrand disease
+∞
10.4
10
*
R52.2
ICD-10 Finland
Other chronic pain
2.5
10.4
80
325
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
3.9
10.4
41
106
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.8
10.3
171
967
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.7
10.3
69
261
G44.2
ICD-10 Finland
Tension-type headache
1.6
10.2
297
1975
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.8
10.2
172
982
N06AB04
ATC
citalopram; systemic
1.4
10.2
468
3440
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.2
365
2548
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
2.6
10.1
75
299
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
10.1
448
3268
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
2.5
10.1
79
327
S22.3
ICD-10 Finland
Fracture of rib
2.0
10.1
128
659
N06AA09
ATC
amitriptyline; systemic
1.7
10.0
205
1238
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.3
10.0
90
398
O02.1
ICD-10 Finland
Missed abortion
1.9
10.0
140
747
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
10.0
321
2185
UDH02
NOMESCO Finland
Rhinopharyngoscopy
1.9
10.0
142
764
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.5
10.0
77
314
R4190
NOMESCO Finland
Nutritional therapy
2.4
9.9
81
343
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.4
9.9
83
354
C09CA06
ATC
candesartan; oral
1.5
9.9
417
3013
3A064
NOMESCO Finland
NA
12.2
9.8
17
14
207
Kela drug reimbursment
Chronic arrhythmias
1.6
9.8
243
1550
Z86.7
ICD-10 Finland
Personal history of diseases of the circulatory system
26.1
9.8
13
5
J01FA09
ATC
clarithromycin; systemic
1.4
9.8
678
5360
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
9.7
318
2171
L01
ICPC
Neck symptom/complaint
1.6
9.7
292
1955
W84
ICPC
Pregnancy high risk
2.2
9.7
94
432
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
9.7
248
1594
-60
ICPC
Result test/procedure
2.0
9.7
129
674
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
3.9
9.7
38
98
L04AA01
ATC
[U] ciclosporin; systemic
3.5
9.6
44
129
M10.9
ICD-10 Finland
Gout, unspecified
2.0
9.6
114
572
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
7.8
9.6
21
27
M13.9
ICD-10 Finland
Arthritis, unspecified
1.9
9.6
146
804
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
9.6
377
2685
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
9.5
159
905
R52.9
ICD-10 Finland
Pain, unspecified
1.8
9.5
178
1048
PEH57
NOMESCO Finland
Bypass from femoral artery to popliteal artery below knee
5.7
9.5
26
46
TAB00
NOMESCO Finland
Lumbar puncture
2.1
9.5
102
492
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.8
9.5
169
982
RS221
NOMESCO Finland
NA
3.5
9.4
42
121
J20
ICD-10 Finland
Acute bronchitis
1.7
9.4
206
1272
RS230
NOMESCO Finland
NA
7.6
9.4
21
28
2869X
ICD-9 Finland
Coagulation defects, Other and unspecified coagulation defects
+∞
9.4
9
*
B02BD06
ATC
von Willebrand factor and coagulation factor VIII in combination; parenteral, topical, urethral
+∞
9.4
9
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.8
9.3
155
879
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
9.3
1050
8904
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
9.3
230
1466
I50
ICD-10 Finland
Heart failure
2.8
9.3
58
210
M35.3
ICD-10 Finland
Polymyalgia rheumatica
2.5
9.2
73
303
I35.0
ICD-10 Finland
Aortic (valve) stenosis
2.1
9.2
100
484
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
9.2
410
2992
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
9.2
182
1090
M79.1
ICD-10 Finland
Myalgia
1.6
9.2
271
1807
J01EA01
ATC
trimethoprim; systemic
1.4
9.2
540
4145
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
3.0
9.1
50
168
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
9.1
200
1236
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.5
9.1
72
298
R01AD05
ATC
budesonide; nasal
1.8
9.1
166
970
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
9.1
285
1925
SBB10
NOMESCO Finland
Teeth copy
1.8
9.1
148
835
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.0
9.1
119
622
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
9.1
251
1650
J02AC01
ATC
fluconazole; systemic
1.3
9.1
922
7700
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.5
9.0
277
1863
Z49.1
ICD-10 Finland
Extracorporeal dialysis
4.0
9.0
34
85
C08CA02
ATC
felodipine; oral
1.8
9.0
165
967
R4130
NOMESCO Finland
Speech therapy
2.9
9.0
52
180
XQ800
NOMESCO Finland
Prick test
1.7
9.0
168
991
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.1
8.9
100
491
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.5
8.9
374
2695
FMD00
NOMESCO Finland
Replacement of aortic valve using mechanical prosthesis
5.5
8.9
25
46
A28
ICPC
Limited function/disability NOS
1.6
8.9
256
1696
C08CA01
ATC
amlodipine; oral
1.4
8.9
605
4753
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
8.8
282
1915
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.8
8.8
138
767
N05BA04
ATC
oxazepam; oral
1.4
8.8
513
3923
I83.1
ICD-10 Finland
Varicose veins of lower extremities with inflammation
3.0
8.8
48
161
R05
ICD-10 Finland
Cough
1.4
8.8
381
2760
I50.1
ICD-10 Finland
Left ventricular failure
2.3
8.8
80
359
L05
ICPC
Flank/axilla symptom/complaint
2.0
8.8
112
579
R01AD08
ATC
fluticasone; nasal
1.4
8.8
608
4789
S20.2
ICD-10 Finland
Contusion of thorax
2.1
8.8
99
489
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.3
8.7
79
353
A02BC03
ATC
lansoprazole; oral
1.4
8.7
574
4482
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.7
8.7
28
60
SPAT1255
SPAT
Intravenous administration of medicine
1.9
8.7
127
691
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
1.9
8.6
115
604
SPAT1260
SPAT
Consultation of another employee
1.5
8.6
360
2588
R81
ICPC
Pneumonia
2.3
8.6
73
316
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.3
8.6
78
348
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.4
8.6
485
3692
K29
ICPC
Cardiovascular sympt/complt other
2.2
8.6
86
403
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
8.6
275
1872
R1260
NOMESCO Finland
Evaluation of communicative skills
3.6
8.5
37
105
H53.4
ICD-10 Finland
Visual field defects
2.9
8.5
49
169
WX872
NOMESCO Finland
Intensive care
2.1
8.5
92
444
C07AA05
ATC
propranolol; systemic
1.4
8.5
411
3042
D07AC01
ATC
betamethasone; topical
1.3
8.5
683
5501
N06AX11
ATC
mirtazapine; oral
1.3
8.5
649
5186
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
8.5
69
293
WZC30
NOMESCO Finland
Teaching
1.6
8.5
243
1610
N02AC04
ATC
dextropropoxyphene; oral
2.4
8.5
71
304
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
2.0
8.5
103
522
NF1AA
NOMESCO Finland
Hip X-ray examination
1.8
8.5
153
891
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.8
8.5
144
823
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
2.9
8.5
50
177
J01DA06
ATC
[U] cefuroxime; systemic
1.5
8.5
310
2171
C08CA05
ATC
nifedipine; systemic
1.9
8.4
129
712
WX610
NOMESCO Finland
Patient controlled analgesia
5.4
8.4
24
45
R03AC03
ATC
terbutaline; inhalant
1.5
8.4
300
2089
D69.5
ICD-10 Finland
Secondary thrombocytopenia
90.3
8.4
9
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.6
8.4
58
225
A06AD11
ATC
lactulose; oral
1.6
8.4
248
1655
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.6
8.4
210
1344
N03AF02
ATC
oxcarbazepine; oral
2.3
8.4
74
328
318
Kela drug reimbursment
Teriparatide
7.9
8.4
18
23
2873A
ICD-9 Finland
Purpura and other haemorrhagic conditions, Primary thrombocytopenia[PURPURA THROMBOCYTOPENICA IDIOPATHICA (ITP)]
+∞
8.3
8
*
K60
ICPC
Cardiovascular, Result test/procedure
5.0
8.3
25
50
C01DA14
ATC
isosorbide mononitrate; oral
1.5
8.3
253
1702
K08.3
ICD-10 Finland
Retained dental root
1.8
8.3
134
756
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
8.3
157
931
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.2
8.3
83
387
A07DA03
ATC
loperamide; oral
2.3
8.3
73
323
N03AX09
ATC
lamotrigine; oral
1.9
8.3
110
579
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
2.5
8.3
64
265
E66.8
ICD-10 Finland
Other obesity
1.9
8.2
120
653
N05CF02
ATC
zolpidem; oral
1.4
8.2
360
2616
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.4
8.2
69
296
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
14.5
8.2
13
9
WX890
NOMESCO Finland
Intesive care monitoring
5.1
8.2
24
47
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.9
8.1
115
618
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.1
8.1
87
420
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.6
8.1
57
225
H05AA02
ATC
teriparatide; parenteral
8.1
8.1
17
21
WW400
NOMESCO Finland
Plasmaferesis
17.2
8.1
12
7
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
8.0
495
3822
N03AE01
ATC
clonazepam; systemic
1.9
8.0
112
600
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
8.0
174
1071
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
2.9
8.0
47
166
ZX108
NOMESCO Finland
Inhalation
5.3
8.0
23
44
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
2.4
8.0
65
276
J05AB11
ATC
valaciclovir; oral
1.5
8.0
269
1852
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.6
7.9
231
1535
J01FA15
ATC
telithromycin; oral
1.6
7.9
202
1299
R4150
NOMESCO Finland
Neuropsychological rehabilitation
4.4
7.9
27
62
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.5
7.9
278
1931
C01BD01
ATC
amiodarone; systemic
2.7
7.9
52
198
4538X
ICD-9 Finland
Other venous embolism and thrombosis, Of other specified veins
13.1
7.9
13
10
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
7.8
7.9
17
22
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.5
7.9
26
58
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.8
591
4706
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
7.8
184
1162
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.5
7.8
229
1526
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
1.5
7.8
238
1603
UKC02
NOMESCO Finland
Cystoscopy
1.5
7.8
275
1910
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
7.7
191
1220
XX9XW
NOMESCO Finland
NA
4.8
7.7
24
50
XLA10
NOMESCO Finland
NA
1.9
7.7
108
579
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
3.2
7.7
39
125
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
1.6
7.7
203
1318
TGC00
NOMESCO Finland
Bronchial lavation
2.8
7.7
47
171
D69.2
ICD-10 Finland
Other nonthrombocytopenic purpura
45.1
7.7
9
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
2.2
7.7
72
328
A12BA01
ATC
potassium chloride; oral
2.1
7.7
82
396
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
7.7
195
1254
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
4.1
7.7
28
69
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
7.4
7.7
17
23
AAD05
NOMESCO Finland
Evacuation of acute subdural haematoma
7.4
7.7
17
23
WX882
NOMESCO Finland
High dependency care
2.5
7.7
58
239
M54.5
ICD-10 Finland
Low back pain
1.3
7.6
685
5592
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.3
7.6
36
110
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.2
7.6
71
322
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
3.4
7.6
35
105
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.5
7.6
226
1512
R04.2
ICD-10 Finland
Haemoptysis
2.4
7.6
63
271
W10
ICD-10 Finland
Fall on and from stairs and steps
1.9
7.6
99
519
D69.8
ICD-10 Finland
Other specified haemorrhagic conditions
18.4
7.6
11
6
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
7.6
107
577
G03DB01
ATC
dydrogesterone; oral
1.5
7.6
298
2119
742
NOMESCO Finland
NA
11.9
7.6
13
11
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.3
7.6
36
111
XMA22
NOMESCO Finland
General examination of pregnant woman
1.7
7.5
145
865
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
8.9
7.5
15
17
PG1UT
NOMESCO Finland
Percutaneous aspiration throbectomy
8.9
7.5
15
17
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.9
7.5
108
584
A91
ICPC
Abnormal result investigation NOS
2.1
7.5
83
407
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
7.5
1590
14459
A12AA04
ATC
calcium carbonate; oral
3.5
7.5
33
96
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.2
7.5
73
340
Z00.0
ICD-10 Finland
General medical examination
1.4
7.5
363
2686
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.0
7.5
41
140
A07AA02
ATC
nystatin; oral
1.8
7.4
119
670
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.7
7.4
135
791
D69.4
ICD-10 Finland
Other primary thrombocytopenia
80.3
7.4
8
*
R03BB04
ATC
tiotropium bromide; inhalant
1.6
7.4
175
1106
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
1.5
7.4
265
1845
N92.6
ICD-10 Finland
Irregular menstruation, unspecified
1.7
7.4
145
868
SPAT1263
SPAT
Sampling
1.3
7.4
914
7779
WX730
NOMESCO Finland
Conventional respirator
3.2
7.4
36
113
7100A
ICD-9 Finland
Diffuse diseases of connective tissue, Systemic lupus erythematosus
13.4
7.4
12
9
M35.1
ICD-10 Finland
Other overlap syndromes
6.0
7.4
19
32
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.4
7.4
314
2266
J01CA08
ATC
pivmecillinam; oral
1.3
7.4
887
7525
E87.6
ICD-10 Finland
Hypokalaemia
2.4
7.4
58
243
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.8
7.3
120
680
R56.8
ICD-10 Finland
Other and unspecified convulsions
1.9
7.3
97
512
R11
ICD-10 Finland
Nausea and vomiting
1.6
7.3
166
1038
G03FA14
ATC
dydrogesterone and estrogen; systemic (progestogens and estrogens, fixed comb.)
0.4
7.3
25
654
RS222
NOMESCO Finland
NA
3.4
7.3
33
98
2860A
ICD-9 Finland
Coagulation defects, Congenital factor VIII disorder
+∞
7.3
7
*
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.5
7.3
218
1461
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
2.4
7.3
58
245
L01XX05
ATC
hydroxycarbamide; oral
4.2
7.3
26
63
L04AA13
ATC
leflunomide; oral
2.5
7.3
54
218
D45
ICD-10 Finland
Polycythaemia vera
4.9
7.3
22
45
N06AX21
ATC
duloxetine; oral
1.5
7.3
216
1444
L12
ICPC
Hand/finger symptom/complaint
1.5
7.2
281
1991
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.5
7.2
54
220
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
1.9
7.2
102
552
R03BA08
ATC
ciclesonide; inhalant
1.6
7.2
160
996
N05BA01
ATC
diazepam; systemic, rectal
1.5
7.2
254
1763
L29
ICPC
Musculoskeletal sympt/complt other
1.7
7.2
140
840
B28
ICPC
Limited function/disability (B)
7.3
7.2
16
22
RD210
NOMESCO Finland
NA
2.7
7.2
46
171
N18.0
ICD-10 Finland
End-stage renal disease
3.9
7.2
27
69
I35.1
ICD-10 Finland
Aortic (valve) insufficiency
2.0
7.1
87
445
I82.1
ICD-10 Finland
Thrombophlebitis migrans
30.1
7.1
9
*
D07AB08
ATC
desonide; topical
1.5
7.1
220
1484
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
4.2
7.1
25
60
R03BA01
ATC
beclometasone; inhalant
1.5
7.1
282
2008
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
7.1
142
856
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
12.0
7.1
12
10
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.8
7.1
43
157
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
2.6
7.1
47
181
I74.2
ICD-10 Finland
Embolism and thrombosis of arteries of upper extremities
10.0
7.0
13
13
K07.60
ICD-10 Finland
Snapping jaw
1.8
7.0
108
601
R01AD12
ATC
fluticasone furoate; nasal
1.3
7.0
636
5187
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
4.3
7.0
24
56
AN1
HP
Coronary angiography
1.6
7.0
191
1253
J45
ICD-10 Finland
Asthma
1.6
7.0
198
1309
C03AA03
ATC
hydrochlorothiazide; oral
1.6
7.0
158
989
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
2.6
7.0
47
183
TPH00
NOMESCO Finland
Phlebotomy
6.3
6.9
17
27
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.6
6.9
157
980
R5599
NOMESCO Finland
Other rehabilitation service
2.3
6.9
59
259
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
5.5
6.9
19
35
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
5.5
6.9
19
35
Z95.8
ICD-10 Finland
Presence of other cardiac and vascular implants and grafts
5.8
6.9
18
31
K84
ICPC
Heart disease other
2.5
6.9
52
214
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
2.4
6.8
52
215
M05BX04
ATC
denosumab; parenteral
2.0
6.8
78
389
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
4.8
6.8
21
44
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
2.7
6.8
42
155
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
8.3
6.8
14
17
UJH02
NOMESCO Finland
Anoscopy
2.0
6.8
82
417
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.5
6.8
230
1585
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
2.5
6.8
51
207
L03.0
ICD-10 Finland
Cellulitis of finger and toe
1.7
6.8
136
819
WW200
NOMESCO Finland
Immunization
2.2
6.8
64
295
PHM76
NOMESCO Finland
Endovenous obliteration of v.saphena magna
2.1
6.8
75
368
J05AB01
ATC
aciclovir; systemic
1.4
6.8
428
3310
I82.80
ICD-10 Finland
Emboli and thrombosis in the subclavian vein
9.3
6.8
13
14
R52.0
ICD-10 Finland
Acute pain
2.1
6.8
70
333
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
4.0
6.8
25
63
N18.8
ICD-10 Finland
Other chronic renal failure
2.4
6.8
52
217
JAH00
NOMESCO Finland
Laparotomy
2.4
6.8
54
228
PD4ST
NOMESCO Finland
Endovascular thrombolysis of pelvic and lower extremity arteries
16.7
6.7
10
6
SPAT1231
SPAT
Assessment of adjustments needed in living environment
2.9
6.7
39
137
R1250
NOMESCO Finland
Evaluation of functional capability
2.5
6.7
48
192
R5110
SPAT
NA
2.4
6.7
52
218
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
2.4
6.7
51
211
R60.9
ICD-10 Finland
Oedema, unspecified
1.9
6.7
90
479
UGC12
NOMESCO Finland
Flexible bronchoscopy
1.7
6.7
125
740
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
1.7
6.7
123
724
PH2AE
SPAT
NA
3.1
6.7
34
111
R06AE09
ATC
levocetirizine; oral
1.4
6.7
301
2195
PH2DE
NOMESCO Finland
Ultrasound examination of bloodflow in veins of lower extremity with Doppler method
2.4
6.7
52
219
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.9
6.7
89
469
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.8
6.7
112
640
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.4
6.6
310
2278
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
6.4
6.6
16
25
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
6.4
6.6
16
25
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
3.1
6.6
34
112
M05BA07
ATC
risedronic acid; oral
2.3
6.6
56
244
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
2.7
6.6
43
163
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.5
6.6
47
188
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
1.7
6.6
134
812
C10AA03
ATC
pravastatin; oral
1.8
6.6
115
666
N25.0
ICD-10 Finland
Renal osteodystrophy
12.3
6.6
11
9
M01AH02
ATC
rofecoxib; oral
1.5
6.6
227
1572
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.4
6.6
50
207
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
2.6
6.6
43
164
K01.0
ICD-10 Finland
Embedded teeth
2.5
6.6
47
189
SPAT1104
SPAT
Monitoring of emergency patient
1.7
6.5
125
744
RS220
NOMESCO Finland
NA
3.0
6.5
34
113
O22.0
ICD-10 Finland
Varicose veins of lower extremity in pregnancy
10.0
6.5
12
12
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.5
6.5
235
1642
J01.4
ICD-10 Finland
Acute pansinusitis
4.3
6.5
22
51
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.5
836
7122
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.6
6.5
178
1168
K04.7
ICD-10 Finland
Periapical abscess without sinus
1.8
6.5
105
594
Z71.9
ICD-10 Finland
Counselling, unspecified
1.7
6.5
119
700
M10.0
ICD-10 Finland
Idiopathic gout
2.3
6.5
56
249
A60
ICPC
General and Unspecified, Result test/procedure
1.9
6.4
88
472
JN4CD
NOMESCO Finland
Very extensive body CT
2.1
6.4
71
351
XCK10
NOMESCO Finland
Photography of fundus of eye
1.5
6.4
186
1235
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
2.1
6.4
68
329
M79.7
ICD-10 Finland
Fibromyalgia
2.1
6.4
70
342
E000006
ATC
NA
1.7
6.4
136
836
ZZA00
NOMESCO Finland
Split skin graft
2.3
6.4
56
250
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
2.1
6.4
65
307
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.1
6.4
72
356
O22.8
ICD-10 Finland
Other venous complications in pregnancy
14.3
6.4
10
7
M01AH01
ATC
celecoxib; oral (coxibs)
1.4
6.4
323
2408
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
1.8
6.4
95
526
E000003
ATC
NA
1.9
6.3
91
497
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
1.7
6.3
130
792
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.6
6.3
140
873
PG1PT
NOMESCO Finland
Extensive endovascular embolisation for bleeding with radiological guidance not elsewhere classified
6.0
6.3
16
27
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
6.0
6.3
16
27
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
1.9
6.3
84
444
A04
ICPC
Weakness/tiredness general
1.4
6.3
262
1883
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.6
6.3
152
968
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
3.7
6.3
25
68
2867X
ICD-9 Finland
Coagulation defects, Acquired coagulation factor deficiency[DEFECTIO COAGULATIONIS, E DEFICIENTIA NON DEFINITA]
+∞
6.3
6
*
2BDXX
NOMESCO Finland
NA
+∞
6.3
6
*
O991, D680
ICD-10 Finland
NA
+∞
6.3
6
*
C02KX05
ATC
riociguat; oral
+∞
6.3
6
*
M362, D66
ICD-10 Finland
NA
+∞
6.3
6
*
D67
ICD-10 Finland
Hereditary factor IX deficiency
+∞
6.3
6
*
28600
ICD-8 Finland
Coagulation defects, Haemophilia
+∞
6.3
6
*
O991, D688
ICD-10 Finland
NA
+∞
6.3
6
*
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.9
6.2
82
433
PBE09
NOMESCO Finland
Thrombectomy or embolectomy of brachial artery
26.7
6.2
8
*
I82.0
ICD-10 Finland
Budd-Chiari syndrome
26.7
6.2
8
*
GD2SN
NOMESCO Finland
Lung ventilation SPECT
4.8
6.2
19
40
PWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of peripheral vessels and lymphatic system
7.0
6.2
14
20
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.5
6.2
207
1423
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
2.1
6.2
67
329
H53.2
ICD-10 Finland
Diplopia
2.2
6.2
57
261
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.8
6.2
106
610
N19
ICD-10 Finland
Unspecified kidney failure
2.3
6.2
54
241
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
2.7
6.2
38
141
TK810
NOMESCO Finland
Hemofiltration
5.0
6.2
18
36
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
3.8
6.2
24
64
D06
ICPC
Abdominal pain localized other
1.6
6.2
168
1104
T14.0
ICD-10 Finland
Superficial injury of unspecified body region
3.3
6.1
28
85
T78.2
ICD-10 Finland
Anaphylactic shock, unspecified
3.1
6.1
30
96
G40.9
ICD-10 Finland
Epilepsy, unspecified
2.1
6.1
66
323
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.5
6.1
200
1369
Z45.0
ICD-10 Finland
Adjustment and management of cardiac devices
2.0
6.1
68
337
R05
ICPC
Cough
1.3
6.1
444
3503
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
6.1
739
6242
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
6.1
812
6937
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
2.8
6.1
36
130
GD1AD
NOMESCO Finland
Thorax CT examination
2.0
6.1
74
378
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
3.7
6.1
24
65
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
1.8
6.1
105
608
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
2.6
6.1
41
161
M03BC51
ATC
orphenadrine, combinations; systemic
1.3
6.1
576
4720
GD1LA
NOMESCO Finland
GD
3.4
6.0
27
81
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
6.0
305
2270
J01MA01
ATC
ofloxacin; systemic
1.6
6.0
151
972
JN4AD
NOMESCO Finland
Body CT examination
1.7
6.0
120
725
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
363
374
10.96
320.42
1.9
1.2
12.9
3.6
u/ml
3.77
149
123
1123
3172
5.17
307.65
5.4
2.1
33.4
29.7
s
23.70
1089
3062
665
644
13.13
307.65
4.8
2.8
3.3
3.6
g/l
3.98
625
608
811
633
17.46
307.65
5.5
2.7
149.2
182.2
%
13.04
770
605
668
717
11.83
307.65
4.5
2.5
96.9
92.0
%
4.75
626
664
339
363
10.45
290.47
1.9
1.2
10.2
3.9
u/ml
4.67
169
155
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
185
69
28.59
273.33
1.4
1.1
97.8
110.5
%
1.49
170
63
1382
5603
3.82
270.72
7.0
3.7
85.2
92.2
%
12.09
1337
5447
325
374
9.67
263.40
1.2
1.1
—
—
—
0
0
135
18
78.65
252.58
1.6
1.2
—
—
—
0
0
310
364
9.43
247.06
1.2
1.1
113.0
117.7
%
1.18
287
335
1280
5266
3.58
238.73
3.8
1.7
1.3
1.0
mg/l
1.63
968
3973
166
68
25.85
236.93
1.4
1.1
90.3
90.3
%
0.00
94
34
195
122
17.07
231.44
1.6
2.8
98.4
97.6
%
0.08
179
114
164
72
24.10
227.93
1.2
1.1
91.3
87.6
%
0.45
90
36
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
369
642
6.45
206.98
6.0
3.2
0.3
0.4
u/ml
0.69
236
352
1625
8332
3.19
200.89
23.3
8.4
1.6
1.2
inr
28.11
543
2507
238
261
9.85
199.08
1.2
1.1
87.3
95.7
%
2.96
223
250
883
3371
3.34
176.97
4.8
3.4
0.8
0.8
mmol/l
0.47
843
3157
169
137
13.04
173.15
1.5
1.2
—
—
—
0
0
724
2512
3.52
168.26
47.3
22.9
1.8
1.3
inr
6.71
57
379
(3002348) Coagulation factor XII activity actual/normal in Platelet poor plasma by Coagulation assay
112
43
27.06
163.17
1.2
1.2
77.0
70.0
%
0.37
40
11
110
43
26.56
159.21
1.2
1.1
88.3
82.2
%
0.45
44
11
732
2900
3.04
133.13
3.9
2.5
22.9
23.2
%
0.17
683
2482
619
2264
3.21
128.87
4.4
3.9
235.6
243.6
u/l
0.60
598
2138
760
3137
2.93
127.76
3.7
2.4
2.3
2.4
g/l
1.14
720
2914
787
3451
2.76
116.72
3.8
2.4
13.2
13.5
umol/l
0.64
753
3191
1715
10977
2.39
110.18
8.5
5.8
2.8
2.8
%
0.54
1631
10218
1715
11041
2.37
107.76
8.8
6.1
8.5
8.4
%
0.75
1634
10349
1824
12138
2.38
104.97
8.6
6.0
0.2
0.2
e9/l
0.34
1621
10744
1808
12052
2.35
102.62
8.4
5.8
1.9
1.9
e9/l
1.74
1596
10713
1501
9341
2.27
99.20
6.4
4.6
35.6
35.8
g/l
0.56
1414
8691
1725
11382
2.29
98.69
8.6
5.9
27.5
28.4
%
2.66
1639
10639
1703
11218
2.27
97.25
8.4
5.7
58.0
57.1
%
2.34
1625
10516
265
700
4.07
89.16
3.2
1.8
0.2
0.2
g/l
3.07
255
662
124
166
7.76
87.68
1.6
1.1
1.2
1.0
ratio
3.20
53
70
269
727
3.98
87.66
3.1
1.7
1.1
1.2
g/l
1.16
259
689
1894
13485
2.19
83.04
11.3
8.5
4.1
4.1
e9/l
0.17
1674
11818
1490
9713
2.11
81.99
9.3
5.8
1.2
1.2
mmol/l
1.18
1399
8817
1057
6094
2.16
79.81
4.2
3.0
0.4
0.4
e6/l
0.01
816
4609
1548
10366
2.07
77.70
13.7
8.8
0.0
0.0
e9/l
1.05
1253
8450
1666
11464
2.08
77.58
7.2
5.7
11.5
11.1
umol/l
0.61
1592
10839
1589
10773
2.06
76.73
9.5
6.4
1.2
1.2
mmol/l
1.31
1363
9099
762
3906
2.29
76.43
3.5
2.8
2.4
2.4
mmol/l
0.78
685
3419
1120
6688
2.11
76.37
4.4
3.1
43.4
98.6
e6/l
1.50
878
5127
529
2305
2.59
76.09
3.7
2.5
1.9
1.8
%
1.03
466
2063
1012
5913
2.10
72.24
3.2
2.2
3.1
2.9
mg/l
1.48
886
5074
2221
17308
2.25
71.09
10.4
7.0
77.1
76.8
u/l
0.11
2122
16309
1191
7445
2.02
70.15
3.8
3.2
2.3
2.3
mmol/l
0.65
1078
6593
235
691
3.61
67.39
1.7
1.6
105.0
145.9
titre
0.46
12
27
98
141
7.16
64.93
1.5
1.1
69.2
31.7
u/ml
0.48
16
13
1760
13014
1.91
59.20
7.0
4.6
6.5
6.6
mmol/l
2.41
1675
12057
731
4041
2.08
58.39
4.6
3.6
311.2
382.8
ng/l
0.27
539
2872
84
121
7.12
55.58
1.1
1.1
90.1
92.0
%
0.20
70
96
637
3429
2.10
54.11
3.7
2.8
2.6
2.8
e6/l
0.25
331
1855
1559
11281
1.83
54.03
4.3
2.8
111.9
100.7
ug/l
0.89
1474
10533
118
244
5.00
53.83
2.3
1.7
38.6
26.2
iu/ml
0.90
21
18
1005
6357
1.89
53.57
2.8
2.1
181.3
205.9
u/l
0.48
971
5996
798
4702
1.97
52.47
3.5
2.5
5.7
6.7
e6/l
1.01
714
4116
399
1796
2.42
52.20
9.9
7.5
9.6
9.3
mmol/l
0.29
380
1712
386
1732
2.42
50.78
2.8
2.6
78.3
69.0
ml/min/173m2
5.81
262
676
534
2777
2.13
49.19
8.6
5.7
1.0
1.0
mmol/l
0.63
505
2581
500
2557
2.16
47.99
3.4
2.6
7.5
7.5
umol/l
0.01
439
2199
1136
7677
1.79
47.47
3.8
3.1
30.6
32.1
u/l
0.75
1080
7308
356
1589
2.42
47.22
2.8
2.7
66.2
66.6
g/l
0.46
334
1464
238
891
2.82
45.15
2.5
1.8
1.4
1.5
g/l
1.05
210
782
641
3667
1.96
44.99
3.4
2.6
0.7
1.2
e6/l
3.23
337
2083
893
5699
1.82
44.55
3.4
2.5
1550.1
5162.1
umol/l
4.09
784
4979
2103
17201
1.83
43.48
5.7
3.9
12.9
11.4
mm/h
4.23
1993
15969
176
567
3.24
43.45
2.6
2.5
0.2
0.0
g/l
0.44
162
526
866
5519
1.81
43.14
3.7
3.0
1613.1
1361.5
ng/l
0.98
729
4655
242
936
2.73
43.10
1.4
1.3
0.3
1.0
u/ml
—
10
84
365
1713
2.30
42.97
3.2
2.7
10.5
10.6
g/l
0.22
345
1573
256
1021
2.65
42.91
7.0
4.3
24.1
24.0
mmol/l
0.32
233
930
168
531
3.30
42.78
2.4
2.5
0.0
0.0
g/l
0.50
154
492
167
527
3.30
42.63
2.4
2.5
0.0
0.0
g/l
0.00
154
491
89
178
5.13
42.18
1.3
1.1
—
—
—
0
0
89
179
5.10
41.91
1.3
1.1
—
—
—
0
0
418
2104
2.15
41.34
3.0
2.4
77.6
60.3
u/l
0.13
369
1786
88
178
5.07
41.17
1.3
1.1
—
—
—
0
0
182
619
3.07
40.98
1.4
1.2
6.5
2.7
u/ml
0.89
24
68
175
582
3.14
40.95
2.4
2.4
37.0
37.6
g/l
0.72
157
511
88
179
5.04
40.91
1.3
1.1
—
—
—
0
0
88
179
5.04
40.91
1.3
1.1
—
—
—
0
0
475
2522
2.06
40.77
11.4
6.9
104.9
104.5
mmol/l
1.04
468
2461
185
639
3.03
40.55
2.7
2.6
0.6
1.1
g/l
1.46
164
568
194
689
2.95
40.47
3.5
2.3
516.5
443.7
ug/l
0.11
183
637
597
3442
1.93
40.45
2.1
1.8
—
—
—
0
0
301
1336
2.40
40.17
2.1
1.8
1.3
1.4
g/l
0.49
284
1232
207
765
2.84
40.15
3.1
1.9
—
—
—
0
0
1922
15505
1.72
39.43
5.6
4.2
256.9
1737.3
e6/l
2.06
29
200
447
2350
2.07
39.30
2.0
1.7
—
—
—
0
0
444
2329
2.07
39.27
2.0
1.7
—
—
—
0
0
190
685
2.90
38.56
1.3
1.2
64.0
30.7
u/ml
0.75
15
44
345
1660
2.23
38.04
3.7
2.5
76.8
70.1
e9/l
1.92
219
1259
1461
11026
1.66
38.02
5.0
4.0
—
—
—
0
0
179
631
2.96
37.82
1.4
1.2
16.6
8.2
u/ml
0.60
33
106
192
709
2.83
37.26
2.5
2.5
3.3
3.1
g/l
1.02
161
560
188
695
2.82
36.40
2.4
2.5
10.6
10.3
g/l
0.37
166
597
197
750
2.75
36.07
2.5
2.5
3.7
3.8
g/l
0.17
161
544
197
751
2.74
35.98
2.5
2.5
7.2
7.4
g/l
0.89
163
575
197
751
2.74
35.98
2.5
2.5
—
—
—
0
0
156
524
3.09
35.86
1.3
1.2
47.7
41.7
u/ml
0.18
24
53
841
5559
1.73
35.65
3.1
2.2
—
—
—
0
0
355
1778
2.14
35.27
10.9
7.3
1.3
1.4
mmol/l
0.07
340
1702
147
487
3.13
34.59
1.2
1.2
2.2
3.9
u/ml
—
9
36
2306
19977
1.78
32.45
29.3
15.4
13.8
13.6
%
9.37
2277
19547
376
1987
2.03
32.21
2.6
2.2
0.2
0.2
g/l
0.12
354
1856
143
487
3.04
32.09
1.2
1.2
—
7.0
—
0
8
106
301
3.62
31.86
1.3
1.3
88.3
49.7
u/ml
—
6
21
135
450
3.10
31.43
1.3
1.3
—
—
—
0
0
135
450
3.10
31.43
1.3
1.3
—
—
—
0
0
315
1599
2.09
30.01
4.8
3.8
104.4
86.4
ng/l
1.67
280
1403
1096
8029
1.59
29.79
4.2
3.3
37.4
45.1
ng/l
0.43
662
4958
1268
9633
1.57
29.28
2.9
2.2
76.6
76.0
nmol/l
0.35
1176
8750
152
565
2.78
29.09
3.5
3.5
8.1
1.7
ratio
0.43
11
50
321
1660
2.05
29.05
3.6
2.9
281.3
196.6
ng/l
1.93
288
1504
154
580
2.75
28.75
3.6
3.5
29.6
82.9
mg/l
1.48
129
479
2600
23610
2.06
28.71
23.5
12.8
22.6
22.4
mg/l
0.09
2252
18516
228
1037
2.30
28.54
12.5
10.1
24.1
24.3
mmol/l
0.39
216
977
153
580
2.73
28.20
5.0
4.5
1.6
1.5
mg/l
0.54
145
542
404
2293
1.89
27.84
10.6
7.7
5.1
5.1
kpa
0.13
387
2190
404
2294
1.89
27.80
10.6
7.7
12.2
12.5
kpa
0.51
385
2193
1172
8822
1.55
27.73
2.3
1.9
95.2
96.0
pmol/l
0.23
662
4655
152
580
2.71
27.67
3.7
3.5
47.6
65.8
mg/l
0.69
128
479
726
4908
1.64
26.96
1.8
1.4
2.3
2.3
g/l
0.10
472
3051
400
2291
1.87
26.73
10.5
7.7
0.6
1.0
mmol/l
1.16
328
1766
296
1553
2.01
25.63
1.8
1.7
—
—
—
0
0
2591
23669
1.96
25.53
25.5
14.4
3.9
3.9
mmol/l
2.65
2549
23002
2585
23596
1.95
25.53
25.3
14.3
139.4
139.6
mmol/l
2.62
2548
22968
385
2214
1.85
25.33
4.4
3.1
—
—
—
0
0
38
56
6.86
24.62
1.8
1.1
88.2
94.9
%
0.54
38
56
38
56
6.86
24.62
1.7
1.1
—
—
—
0
0
119
428
2.86
24.23
1.4
1.4
120.5
113.1
u/ml
0.16
22
75
356
2031
1.86
23.95
11.4
8.3
95.6
95.6
%
0.00
342
1958
67
173
3.94
23.13
1.3
1.2
98.8
207.5
titre
—
8
32
240
1211
2.07
23.07
1.7
1.6
—
—
—
0
0
178
801
2.30
22.79
1.4
1.3
—
—
—
0
0
2406
21691
1.67
22.27
21.4
11.6
84.5
84.7
ml/min/173m2
0.13
2113
17827
335
1917
1.85
22.25
6.7
3.9
1.7
1.9
mmol/l
0.24
280
1521
119
449
2.72
22.16
3.9
3.6
59.1
57.8
%
0.55
119
449
114
421
2.78
22.11
3.4
2.4
17.3
16.4
%
1.37
50
211
328
1880
1.84
21.65
12.2
8.6
120.9
121.7
g/l
0.28
318
1808
332
1928
1.82
20.98
6.7
3.8
6.0
5.8
kpa
1.50
318
1868
212
1059
2.08
20.91
12.4
11.1
—
—
—
0
0
373
2259
1.75
20.41
2.3
2.1
345.4
372.4
nmol/l
2.03
351
2073
78
243
3.27
20.38
1.1
1.0
—
—
—
0
0
614
4226
1.58
20.37
1.3
1.3
25.8
30.2
iu/ml
0.48
172
1316
141
605
2.40
20.13
1.9
1.6
—
—
—
0
0
920
6980
1.47
19.03
2.8
2.5
54.8
56.4
u/l
0.74
865
6470
1398
11484
1.42
18.70
4.3
3.5
0.0
0.0
estimate
0.50
319
2171
97
371
2.67
17.63
1.7
1.4
—
—
—
0
0
1834
15904
1.42
17.52
3.5
3.0
48.3
42.9
u/l
2.06
1730
14969
55
152
3.67
17.31
1.2
1.2
—
—
—
0
0
1399
11619
1.40
16.90
4.4
3.5
0.0
0.0
estimate
1.32
327
2150
111
470
2.42
16.36
1.3
1.2
268.7
260.4
u/ml
0.07
78
287
1381
11495
1.39
16.20
6.0
4.7
0.0
0.0
estimate
0.50
338
2205
2377
21785
1.53
15.96
5.6
4.8
1.8
2.1
mu/l
1.46
2237
20247
287
1746
1.72
15.29
5.4
3.4
1.2
1.2
mmol/l
2.30
261
1503
670
4955
1.46
15.22
1.8
1.5
19.6
20.6
nmol/l
0.94
586
4282
267
1596
1.74
15.15
5.5
3.3
4.8
4.7
kpa
0.49
251
1540
113
500
2.31
15.10
1.3
1.2
—
—
—
0
0
548
3909
1.50
14.91
2.0
1.7
1106.4
1172.2
nmol/l
0.88
431
2981
102
439
2.37
14.53
6.7
5.3
2437.4
387.2
iu/ml
—
7
56
2077
18659
1.41
14.49
4.8
4.1
14.6
14.6
pmol/l
0.16
1948
17204
35
79
4.47
14.48
1.2
1.2
—
—
—
0
0
561
4047
1.48
14.38
1.3
1.3
19.2
11.3
u/ml
0.39
177
1658
266
1618
1.71
14.16
3.2
3.3
4.3
4.5
pmol/l
2.76
237
1445
123
584
2.16
13.88
1.2
1.2
—
—
—
0
0
126
609
2.12
13.59
1.9
2.1
11.8
11.1
mg/l
0.42
117
569
754
5822
1.40
13.21
1.7
1.6
1.4
1.4
mmol/l
1.17
656
4955
34
82
4.18
12.96
7.7
3.9
297.6
75.0
mg/l
0.49
29
62
100
451
2.26
12.82
1.6
1.5
—
—
—
0
0
62
227
2.77
12.35
1.6
1.6
—
—
—
0
0
438
3096
1.49
12.27
2.2
2.4
136.3
115.5
ug/g
0.56
344
2455
2620
24844
1.62
11.94
14.8
9.5
26.5
25.4
u/l
1.82
2556
24051
730
5692
1.38
11.85
1.4
1.3
0.7
1.5
u/ml
4.94
187
1555
256
1622
1.63
11.64
1.4
1.3
115.7
213.7
u/ml
2.93
241
1499
171
971
1.81
11.56
2.1
2.0
38.8
39.0
u/l
0.03
149
880
84
370
2.31
11.42
1.6
1.6
—
—
—
0
0
98
461
2.17
11.37
2.9
2.2
130.8
131.1
g/l
0.04
76
352
71
293
2.46
11.16
1.6
1.5
—
—
—
0
0
2368
22059
1.42
11.15
26.4
13.7
39.4
39.7
%
1.21
1872
16697
60
234
2.60
10.62
12.7
6.7
6.7
7.3
mmol/l
0.87
53
198
105
525
2.04
10.42
1.6
1.5
—
—
—
0
0
206
1271
1.67
10.39
1.7
1.5
—
—
—
0
0
54
210
2.60
9.64
1.3
1.2
44.1
64.7
u/l
1.59
41
147
101
516
1.99
9.47
1.6
1.6
—
—
—
0
0
249
1647
1.56
9.45
2.3
2.4
25.9
22.2
au/ml
—
8
114
9
0
+∞
9.38
2.4
0.0
—
—
—
0
0
17
30
5.69
9.27
1.8
1.7
—
—
—
0
0
16
27
5.95
9.12
12.9
10.1
6.4
6.3
mmol/l
0.03
16
27
47
176
2.70
9.06
4.0
1.6
—
—
—
0
0
39
133
2.96
8.92
1.1
1.0
—
—
—
0
0
128
723
1.81
8.87
1.2
1.1
—
—
—
0
0
115
630
1.86
8.79
2.4
2.9
—
—
—
0
0
799
6581
1.30
8.44
3.8
3.2
7.1
7.6
mmol/l
2.38
686
5591
38
132
2.90
8.43
1.7
1.4
5.1
6.2
u/l
0.78
31
109
2210
20620
1.31
8.32
5.8
5.2
39.0
39.1
mmol/mol
0.36
2053
19227
42
156
2.72
8.25
2.4
2.2
—
—
—
0
0
125
720
1.77
8.14
1.2
1.1
—
—
—
0
0
246
1680
1.51
8.07
2.2
2.3
9.6
6.9
ug/l
0.87
211
1478
198
1300
1.56
7.79
5.6
3.7
1.7
1.7
mmol/l
0.04
145
956
31
103
3.03
7.46
1.8
1.6
—
—
—
0
0
31
103
3.03
7.46
1.8
1.6
—
—
—
0
0
1835
16823
1.25
7.43
3.9
3.4
—
—
—
0
0
12
9
13.38
7.38
1.3
1.0
—
—
—
0
0
77
392
1.99
7.37
1.7
1.6
—
—
—
0
0
125
743
1.71
7.32
1.5
1.6
0.1
8.9
iu/ml
0.50
24
137
119
703
1.72
7.13
1.5
1.3
—
—
—
0
0
137
841
1.66
7.12
1.9
1.7
—
—
—
0
0
44
182
2.44
7.01
1.4
1.3
—
—
—
0
0
20
52
3.87
6.98
3.0
2.0
—
—
—
0
0
201
1359
1.52
6.94
5.6
3.7
5.2
5.2
kpa
0.02
185
1272
154
984
1.60
6.83
1.8
1.8
—
—
—
0
0
14
28
5.02
6.70
2.2
1.7
—
—
—
0
0
15
32
4.71
6.68
5.1
6.3
—
—
—
0
0
64
319
2.03
6.54
1.9
1.2
25.5
35.3
u/l
0.54
58
273
275
2008
1.41
6.38
3.4
4.0
4.1
37.3
ug/l
1.27
202
1590
42
178
2.38
6.38
1.1
1.2
54.6
54.2
u/ml
—
5
17
38
155
2.47
6.27
1.5
1.5
—
—
—
0
0
38
156
2.46
6.19
1.8
2.5
627.5
770.8
e6/l
0.53
11
63
78
425
1.86
6.17
2.8
2.4
5.4
6.0
umol/l
0.32
58
313
206
1437
1.47
6.12
2.6
2.2
3670.8
5257.5
u/l
0.56
88
569
105
627
1.70
6.10
1.5
1.4
304.7
296.5
ug/g
0.14
59
346
630
5220
1.26
6.07
1.8
1.6
—
—
—
0
0
9
6
15.04
5.90
1.1
1.0
—
—
—
0
0
113
696
1.65
5.86
3.3
3.4
560.4
5871.5
u/ml
0.73
92
593
38
162
2.36
5.73
2.1
2.1
10.9
12.5
%
0.42
18
90
78
436
1.81
5.71
5.1
2.7
34.6
34.2
umol/l
0.06
67
370
730
6188
1.24
5.71
4.9
4.0
12.6
9.6
mg/mmol
0.86
489
3956
139
913
1.55
5.53
5.7
2.8
0.6
0.7
%
2.11
134
885
375
2941
1.32
5.51
1.7
1.8
1.5
1.4
%
0.29
326
2608
69
376
1.86
5.49
1.7
1.4
—
—
—
0
0
109
677
1.63
5.49
1.3
1.1
—
—
—
0
0
17
47
3.63
5.48
1.0
1.1
—
—
—
0
0
62
333
1.88
5.18
1.4
1.2
—
—
—
0
0
30
121
2.49
5.12
1.8
2.7
663.8
1125.6
u/ml
1.07
30
121
32
134
2.40
5.05
1.8
1.6
4.5
6.7
u/l
0.56
22
69
721
6174
1.22
5.04
5.0
3.8
0.0
0.0
estimate
1.49
334
2158
40
187
2.16
4.91
1.5
1.3
182011.9
66730.4
e6/l
0.30
27
105
66
370
1.80
4.84
2.6
3.2
0.8
0.8
nmol/l
0.23
51
293
54
284
1.92
4.83
2.7
2.5
5.0
20.3
u/ml
0.54
49
260
2282
21778
1.23
4.81
4.2
3.6
1.3
1.3
mmol/l
1.56
2117
20166
93
576
1.64
4.78
1.3
1.4
—
—
—
0
0
10
20
5.01
4.77
1.5
1.5
0.8
0.6
mg/l
—
5
13
10
20
5.01
4.77
1.5
1.5
5.6
3.6
mg/l
—
5
11
10
20
5.01
4.77
1.5
1.5
1.5
1.6
mg/l
—
5
12
85
515
1.67
4.76
4.8
3.0
24.9
24.8
mmol/l
0.09
78
451
57
307
1.87
4.75
1.3
1.3
—
—
—
0
0
2372
22740
1.25
4.74
4.7
4.0
4.5
4.7
mmol/l
14.08
2221
21276
24
90
2.68
4.74
1.2
1.2
—
—
—
0
0
40
190
2.12
4.73
3.1
3.6
—
—
—
0
0
43
211
2.05
4.68
1.5
1.4
7480.6
1970.3
e6/l
0.41
33
146
2404
23092
1.25
4.66
5.2
4.4
2.7
2.8
mmol/l
11.91
2236
21463
54
288
1.89
4.65
1.8
1.4
—
—
—
0
0
192
1400
1.40
4.54
1.3
1.4
—
—
—
0
0
176
1264
1.42
4.54
11.3
7.2
24.9
24.4
mmol/l
1.03
164
1179
43
215
2.02
4.46
1.1
1.2
43.4
37.9
mg/l
0.41
36
177
26
105
2.49
4.46
1.1
1.1
162.4
171.6
iu/ml
0.08
26
105
239
1813
1.35
4.43
1.6
1.5
—
—
—
0
0
86
534
1.63
4.40
1.6
1.5
25.5
30.4
e6/l
0.11
69
423
86
534
1.63
4.40
1.6
1.6
544.6
1303.8
e6/l
0.69
72
443
53
289
1.85
4.29
1.2
1.1
1.5
1.5
g/l
0.06
53
263
66
386
1.73
4.24
1.1
1.1
—
—
—
0
0
41
206
2.00
4.22
1.0
1.1
219.0
234.4
mg/l
0.27
33
176
2352
22597
1.22
4.20
4.7
4.0
1.4
1.5
mmol/l
9.60
2181
21022
117
793
1.50
4.11
1.4
1.4
11.5
10.4
u/l
0.29
89
643
169
1233
1.39
4.02
5.7
3.2
125.7
128.9
g/l
1.03
164
1201
115
781
1.49
4.01
2.7
1.9
1.7
2.1
ug/l
0.22
99
685
33
156
2.13
3.99
1.1
1.1
1.0
1.1
u/l
0.40
14
73
247
1914
1.32
3.98
1.3
1.2
176.3
154.0
iu/ml
0.28
86
734
80
508
1.59
3.79
1.6
1.8
14420.3
14083.7
e6/l
0.02
50
375
38
194
1.97
3.77
2.5
2.4
—
—
—
0
0
7
8
8.77
3.77
2.3
3.4
—
—
—
0
0
7
8
8.77
3.77
2.1
3.3
—
—
—
0
0
2693
26347
1.35
3.76
34.5
18.8
249.8
257.0
e9/l
6.04
2651
25725
46
252
1.84
3.71
1.1
1.1
—
—
—
0
0
35
175
2.01
3.69
1.3
1.4
—
—
—
0
0
62
372
1.68
3.68
1.1
1.1
—
—
—
0
0
56
327
1.73
3.66
1.5
1.4
—
—
—
0
0
24
103
2.34
3.66
1.2
1.3
—
—
—
0
0
146
1057
1.40
3.66
1.5
1.5
—
—
—
0
0
9
16
5.64
3.65
1.1
1.4
—
—
—
0
0
162
1196
1.38
3.62
1.5
1.4
—
—
—
0
0
98
660
1.50
3.59
1.6
1.9
2.4
4.4
iu/l
5.82
34
256
2693
26366
1.34
3.57
34.4
18.8
4.4
4.5
e12/l
5.01
2648
25684
2693
26371
1.34
3.52
34.5
18.9
6.9
6.8
e9/l
1.91
2647
25681
13
41
3.18
3.49
1.3
1.1
—
—
—
0
0
2693
26376
1.33
3.47
34.7
18.9
132.5
134.6
g/l
12.26
2674
26025
23
101
2.29
3.36
1.2
1.3
—
—
—
0
0
986
8939
1.16
3.35
4.6
3.6
—
—
—
0
0
32
161
2.00
3.34
1.9
2.4
471.3
543.9
e6/l
0.35
23
136
36
190
1.91
3.29
1.3
1.5
29.0
34.2
%
0.33
21
115
25
115
2.18
3.28
1.1
1.1
—
—
—
0
0
206
1605
1.31
3.24
1.4
1.4
23.1
25.6
iu/l
0.62
172
1367
2297
22155
1.18
3.23
4.6
4.1
5.8
5.8
mmol/l
0.33
2101
20371
16
60
2.68
3.22
1.0
1.1
—
—
—
0
0
57
348
1.65
3.21
1.1
1.1
—
—
—
0
0
22
97
2.28
3.19
1.1
1.5
6.4
4.8
%
—
8
18
36
194
1.87
3.11
1.3
1.2
2.9
0.6
u/ml
0.43
18
79
133
980
1.37
3.05
1.5
1.4
—
—
—
0
0
133
981
1.37
3.04
1.5
1.4
—
—
—
0
0
37
204
1.82
2.99
1.0
1.1
—
—
—
0
0
71
468
1.53
2.94
1.2
1.4
—
—
—
0
0
41
237
1.74
2.85
1.1
1.2
—
—
—
0
0
74
496
1.50
2.84
1.7
1.4
0.6
0.5
nmol/l
0.26
60
396
23
109
2.12
2.84
1.7
1.4
—
—
—
0
0
23
109
2.12
2.84
1.7
1.4
—
—
—
0
0
131
978
1.36
2.80
1.5
1.4
—
—
—
0
0
151
1153
1.33
2.78
1.4
1.6
282.4
307.7
mu/l
0.52
136
1032
78
532
1.48
2.77
1.2
1.4
3.6
3.7
mmol/l
0.29
71
502
131
981
1.35
2.75
1.5
1.4
—
—
—
0
0
86
599
1.45
2.74
1.4
1.4
472.9
488.7
mg/l
0.15
80
569
144
1099
1.33
2.67
4.1
2.7
0.1
0.3
e6/l
7.57
139
1058
70
471
1.50
2.66
1.7
1.3
3.1
4.1
ug/l
0.59
65
434
42
250
1.69
2.65
1.4
1.7
—
—
—
0
0
102
739
1.39
2.63
1.1
1.1
2.2
3.8
u/ml
0.57
14
104
7
15
4.68
2.59
1.0
1.1
—
—
—
0
0
177
1396
1.29
2.59
2.3
3.0
30.1
45.5
u/ml
1.36
169
1348
6
11
5.46
2.54
2.8
3.6
—
—
—
0
0
51
324
1.58
2.52
3.8
3.1
1.0
1.5
%
0.78
42
258
29
158
1.84
2.48
2.0
2.4
0.2
0.2
e9/l
0.08
23
136
7
16
4.38
2.47
1.1
1.4
4.3
9.9
u/l
—
7
16
117
877
1.35
2.47
6.4
4.0
24.6
24.7
mmol/l
0.19
108
817
9
27
3.34
2.39
1.2
2.4
—
—
—
0
0
34
200
1.71
2.28
2.5
2.7
—
—
—
0
0
13
53
2.46
2.27
1.1
1.2
—
—
—
0
0
23
120
1.92
2.25
1.0
1.1
1959.2
1468.7
miu/ml
1.54
23
120
50
326
1.54
2.24
4.1
5.4
364.1
367.9
umol/l
0.06
45
283
41
255
1.62
2.24
1.3
1.7
54.4
60.1
%
0.39
27
163
18
86
2.10
2.22
1.0
1.0
—
—
—
0
0
36
217
1.67
2.22
1.8
1.6
—
—
—
0
0
19
93
2.05
2.21
1.1
1.2
—
—
—
0
0
37
225
1.65
2.21
1.5
1.7
—
—
—
0
0
44
280
1.58
2.20
1.6
1.4
—
—
—
0
0
33
195
1.70
2.19
2.0
1.5
—
—
—
0
0
8
24
3.34
2.18
1.0
1.0
—
—
—
0
0
59
403
1.47
2.15
1.1
1.0
1.3
2.1
u/ml
0.71
18
193
38
235
1.63
2.13
1.3
1.4
13.6
12.3
mmol/l
0.24
14
46
17
82
2.08
2.06
4.2
4.2
—
—
—
0
0
30
176
1.71
2.06
1.5
1.3
1.9
1.9
mmol/l
0.04
25
166
23
125
1.85
2.02
1.7
1.4
—
—
—
0
0
113
872
1.31
2.01
1.5
1.5
—
—
—
0
0
22
119
1.86
1.97
1.6
1.3
100.0
71.3
titre
—
5
15
41
265
1.56
1.95
1.2
1.4
—
—
—
0
0
6
16
3.76
1.93
1.0
1.1
—
—
—
0
0
273
2335
1.19
1.93
1.9
1.9
—
—
—
0
0
25
142
1.77
1.92
2.0
1.9
—
—
—
0
0
27
157
1.73
1.92
2.7
1.7
—
—
—
0
0
17
85
2.01
1.90
1.4
1.2
—
—
—
0
0
41
267
1.54
1.89
1.2
1.4
—
—
—
0
0
65
466
1.40
1.87
3.8
2.1
1.0
0.8
nmol/l
0.71
56
388
31
190
1.64
1.84
1.1
1.0
—
—
—
0
0
15
73
2.06
1.80
2.4
1.4
—
—
—
0
0
11
47
2.35
1.77
1.1
1.7
0.2
0.2
nmol/l
—
5
32
40
264
1.52
1.76
1.2
1.5
—
—
—
0
0
31
194
1.60
1.71
1.6
1.6
—
—
—
0
0
31
194
1.60
1.71
1.6
1.6
—
—
—
0
0
31
194
1.60
1.71
1.6
1.6
—
—
—
0
0
40
266
1.51
1.71
1.2
1.4
—
—
—
0
0
351
3100
1.15
1.68
2.9
3.0
0.7
0.8
ug/l
0.13
233
2011
40
268
1.50
1.66
1.2
1.4
—
—
—
0
0
27
165
1.64
1.64
1.0
1.1
9.8
10.4
iu/ml
—
7
42
40
270
1.49
1.61
1.2
1.4
—
—
—
0
0
15
77
1.95
1.59
3.7
2.9
24.4
29.0
umol/l
—
10
59
19
106
1.80
1.58
1.2
1.1
65.2
26.6
u/l
0.30
12
79
26
160
1.63
1.55
1.3
1.4
—
—
—
0
0
19
107
1.78
1.54
1.2
1.1
118.9
84.3
u/l
0.36
14
85
7
28
2.50
1.45
1.1
1.2
—
—
—
0
0
19
110
1.73
1.42
2.3
2.2
37.3
48.7
umol/l
1.28
13
87
64
483
1.33
1.41
1.7
1.6
—
—
—
0
0
118
964
1.23
1.40
1.3
1.3
245.6
218.3
miu/ml
0.33
49
483
28
181
1.55
1.40
1.1
1.2
—
—
—
0
0
19
111
1.72
1.39
2.1
1.8
—
—
—
0
0
73
564
1.30
1.37
1.3
1.2
—
—
—
0
0
422
3830
1.12
1.35
2.2
2.1
—
—
—
0
0
112
916
1.23
1.33
2.3
1.9
—
—
—
0
0
228
2605
0.86
1.33
4.3
4.1
31.7
32.4
%
0.38
170
1824
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
21
128
1.65
1.33
1.0
1.1
—
—
—
0
0
14
76
1.85
1.29
1.0
1.3
—
—
—
0
0
14
76
1.85
1.29
1.0
1.3
—
—
—
0
0
34
234
1.46
1.29
1.5
1.1
—
—
—
0
0
19
114
1.67
1.28
1.6
1.8
—
—
—
0
0
19
114
1.67
1.28
1.6
1.8
—
—
—
0
0
19
114
1.67
1.28
1.6
1.8
—
—
—
0
0
19
114
1.67
1.28
1.6
1.8
—
—
—
0
0
159
1354
1.18
1.26
2.3
2.1
11.0
11.6
nmol/l
0.44
135
1190
162
1382
1.18
1.26
1.1
1.0
—
—
—
0
0
376
3407
1.12
1.25
2.0
2.0
—
—
—
0
0
27
182
1.49
1.15
1.6
1.5
0.9
0.9
g/l
0.38
27
182
25
166
1.51
1.15
1.2
1.2
—
—
—
0
0
25
167
1.50
1.12
1.2
1.2
—
—
—
0
0
49
371
1.33
1.11
1.3
1.3
—
—
—
0
0
31
218
1.43
1.09
1.6
2.2
18.8
19.8
nmol/l
0.23
31
209
7
33
2.12
1.05
1.0
1.0
—
—
—
0
0
35
254
1.38
1.04
3.1
2.3
46.8
25.6
mg/l
—
8
71
5
22
2.27
1.03
2.6
1.7
50.6
45.2
umol/l
—
5
22
49
376
1.31
1.03
2.9
3.6
46.7
1076.8
u/ml
0.89
41
350
538
5017
1.09
1.02
4.5
3.8
1.0
1.0
kg/l
0.44
80
746
9
47
1.92
1.02
1.1
1.2
—
—
—
0
0
5
23
2.18
0.98
1.0
1.0
—
—
—
0
0
14
84
1.67
0.97
1.0
1.2
—
—
—
0
0
9
50
1.80
0.96
1.4
1.4
—
—
—
0
0
15
93
1.62
0.93
1.1
1.2
—
—
—
0
0
13
78
1.67
0.91
1.5
1.1
—
—
—
0
0
15
94
1.60
0.90
2.8
2.3
—
—
—
0
0
569
5350
1.08
0.90
4.3
4.8
3.2
3.9
ug/l
0.27
503
4795
32
237
1.35
0.87
2.9
4.9
242.9
82.6
u/ml
0.30
11
72
25
178
1.41
0.86
1.3
1.1
—
—
—
0
0
11
66
1.67
0.78
3.1
2.8
—
—
—
0
0
51
413
1.24
0.75
1.1
1.2
—
—
—
0
0
5
25
2.00
0.72
2.2
1.3
208.8
95.9
ng/l
—
5
25
64
534
1.20
0.72
2.0
1.7
40.7
40.9
nmol/l
0.02
64
516
95
821
1.16
0.72
2.2
1.8
—
—
—
0
0
7
41
1.71
0.70
1.0
1.2
—
—
—
0
0
48
391
1.23
0.69
3.4
3.7
27.2
28.4
u/ml
0.04
48
380
14
94
1.49
0.66
1.4
1.9
—
—
—
0
0
14
94
1.49
0.66
1.4
1.9
—
—
—
0
0
496
4700
1.07
0.65
1.8
1.6
444.3
31092440.1
pmol/l
3.95
403
3956
21
154
1.37
0.65
1.0
1.1
0.2
8.6
nmol/l
—
6
25
200
1828
1.10
0.64
1.9
1.8
—
—
—
0
0
14
95
1.48
0.64
1.0
1.1
—
—
—
0
0
14
95
1.48
0.64
1.6
1.9
—
—
—
0
0
5
29
1.73
0.64
1.6
2.1
1.8
1.3
mg/l
—
5
24
35
436
0.80
0.62
1.1
1.1
0.5
4.5
u/ml
3.90
14
162
12
79
1.52
0.62
1.1
1.2
—
—
—
0
0
93
815
1.15
0.61
5.0
5.9
2.0
1.6
%
1.48
83
761
41
500
0.82
0.61
3.0
2.5
102.0
94.4
ug/min
0.05
22
311
76
659
1.16
0.59
1.5
1.5
—
—
—
0
0
13
89
1.46
0.58
1.1
1.1
32.6
290.1
ng/l
—
5
19
20
149
1.34
0.57
1.4
1.2
—
—
—
0
0
29
363
0.80
0.56
1.1
1.1
0.1
0.3
u/ml
—
9
90
216
2331
0.92
0.55
1.6
1.6
—
—
—
0
0
21
159
1.32
0.55
1.9
2.0
—
—
—
0
0
6
40
1.50
0.51
1.0
1.2
2.3
5.1
nmol/l
—
6
40
7
46
1.52
0.48
1.0
1.2
—
—
—
0
0
92
1017
0.90
0.42
1.5
1.5
—
—
—
0
0
239
2535
0.94
0.42
8.6
6.5
—
—
—
0
0
14
105
1.33
0.41
2.1
3.0
43.9
170.2
umol/l
—
7
64
53
464
1.14
0.40
1.6
1.4
18.2
23.8
u/l
0.72
46
394
5
35
1.43
0.39
1.4
1.4
—
—
—
0
0
22
178
1.24
0.38
1.0
1.1
—
—
—
0
0
21
170
1.24
0.37
1.5
2.2
2.9
2.0
u/field
0.24
14
72
6
43
1.40
0.35
1.2
1.0
—
—
—
0
0
6
44
1.36
0.34
1.7
1.4
—
—
—
0
0
84
770
1.09
0.32
2.0
1.7
—
—
—
0
0
7
52
1.35
0.31
1.3
1.1
—
—
—
0
0
65
590
1.10
0.30
1.2
1.2
1.0
1.4
u/ml
0.27
30
243
12
153
0.78
0.30
1.4
1.4
5.4
5.7
mmol/l
0.40
12
148
13
103
1.26
0.28
2.5
1.6
—
1277786.7
iu/ml
—
0
9
10
76
1.32
0.28
1.3
1.4
10.4
8.9
ug/l
—
10
76
8
65
1.23
0.27
1.1
1.0
—
—
—
0
0
8
65
1.23
0.27
1.1
1.0
—
—
—
0
0
12
95
1.26
0.26
1.2
1.0
—
—
—
0
0
31
273
1.14
0.25
1.5
1.5
7.9
7.7
mmol/l
0.13
17
163
13
158
0.82
0.23
1.2
1.3
—
—
—
0
0
492
4800
1.03
0.23
1.5
1.5
—
—
—
0
0
43
389
1.11
0.23
1.1
1.1
92.4
1371.4
iu/ml
0.50
14
98
5
41
1.22
0.22
1.2
1.3
—
—
—
0
0
5
42
1.19
0.21
2.2
1.5
—
—
—
0
0
40
363
1.10
0.21
1.4
1.4
6.9
7.3
mmol/l
0.32
27
261
102
964
1.06
0.21
5.3
3.2
25.5
25.2
mmol/l
0.42
97
931
0
13
0.00
0.21
0.0
1.1
—
20.9
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
36.9
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
8.0
—
0
13
19
164
1.16
0.20
2.0
2.4
1136.4
620.5
ml
1.45
11
111
6
50
1.20
0.19
1.7
1.1
—
—
—
0
0
6
51
1.18
0.19
4.0
2.3
15.4
16.5
umol/l
—
6
51
34
374
0.91
0.18
2.5
1.8
190.0
198.6
pmol/l
0.13
34
349
88
926
0.95
0.17
1.5
1.9
—
—
—
0
0
36
392
0.92
0.17
1.1
1.1
1.0
5.0
u/ml
4.18
18
153
8
70
1.14
0.16
1.1
1.1
—
—
—
0
0
23
207
1.11
0.15
3.2
2.9
61.1
55.2
%
0.48
13
143
11
94
1.17
0.13
1.0
2.6
1.7
1.1
ug/l
0.22
11
86
102
1056
0.96
0.11
1.5
1.4
—
—
—
0
0
10
87
1.15
0.09
5.4
3.4
—
—
—
0
0
6
54
1.11
0.09
1.3
1.1
—
—
—
0
0
6
57
1.05
0.08
1.0
1.1
28.4
40.7
u/ml
—
6
57
7
64
1.09
0.08
2.0
2.8
—
—
—
0
0
7
64
1.09
0.08
2.0
2.8
—
—
—
0
0
26
244
1.07
0.08
1.4
1.4
—
—
—
0
0
7
67
1.04
0.08
1.1
1.1
—
—
—
0
0
99
1015
0.97
0.07
1.5
1.7
3.0
4.1
mg/l
0.68
66
700
13
119
1.09
0.06
2.0
1.8
—
—
—
0
0
47
455
1.03
0.05
1.7
1.8
—
—
—
0
0
47
481
0.98
0.03
6.7
3.5
28.6
23.6
mg/l
0.37
35
316
428
4287
1.00
0.00
3.7
4.2
24.0
21.7
%
1.86
172
2011
13
134
0.97
0.00
1.1
2.2
—
—
—
0
0
10
102
0.98
0.00
1.9
2.1
—
203.4
—
0
23
15
152
0.99
0.00
8.9
12.6
759.5
839.8
nmol/l
0.28
15
146
11
107
1.03
0.00
1.0
1.3
186.1
49.9
pmol/l
—
5
36
7
71
0.99
0.00
1.1
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
1026.0
—
0
9
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
0.00
1.0
1.1
42.6
76.8
ug/l
—
5
44
Mortality – FinRegistry
↥Association
Association between endpoint D3_COAGOTHER and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_COAGOTHER | 1.969 [1.68, 2.3] | < 0.001 |
| Birth year | 0.993 [0.98, 1.0] | 0.102 |
During the follow-up period (1.1.1998 — 31.12.2019), 866 out of 9259 females with D3_COAGOTHER died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| D3_COAGOTHER | 2.037 [1.76, 2.36] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 960 out of 4790 males with D3_COAGOTHER died.
Mortality risk
Mortality risk for people of age
years, who have D3_COAGOTHER.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.198% | 0.418% |
| 5 | 1.027% | 2.321% |
| 10 | 2.67% | 5.891% |
| 15 | 4.974% | 10.495% |
| 20 | 8.859% | 18.28% |
Relationships between endpoints
↥Index endpoint: D3_COAGOTHER – Other coagulation defects
GWS hits: 27
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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