Benign neoplasm: Descending colon

CD2_BENIGN_DESCENDING_COLON

colonic neoplasm: A benign or malignant neoplasm that affects the colon. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colonic adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D12.4&
  • Hospital discharge: ICD-8 21135
  • Cause of death: ICD-10 D12.4&
  • Cause of death: ICD-8 21135

2 out of 7 registries used, show all original rules.

2369

4. Check minimum number of events

None

2369

5. Include endpoints

None

2369

6. Filter based on genotype QC (FinnGen only)

2369

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
D12
Name in latin
Neoplasma benignum coli descendentis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 11433 5068 6323
Only index persons 10736 4845 5891
Unadjusted period prevalence (%)
Whole population 0.16 0.15 0.18
Only index persons 0.20 0.18 0.22
Median age at first event (years)
Whole population 67.11 67.05 67.17
Only index persons 66.90 66.85 66.95

-FinnGen-

Key figures

All Female Male
Number of individuals 2369 1074 1295
Unadjusted period prevalence (%) 0.48 0.37 0.57
Median age at first event (years) 66.65 65.28 67.79

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2045
Matched controls
20450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
18.6
323.0
584
431
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
22.3
323.0
800
573
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
30.3
323.0
455
191
UJF32
NOMESCO Finland
Coloscopy
15.2
323.0
1586
3791
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
4503599627370496.0
323.0
2030
11
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
19.8
285.7
448
285
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
12.6
217.3
412
400
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
4.4
168.0
784
2556
UJF30
NOMESCO Finland
Ileoscopy through colon
6.0
164.7
516
1088
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
13.2
150.7
276
239
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
18.1
149.6
239
148
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
7.3
144.6
377
611
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.3
129.0
951
4295
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
4.7
103.2
396
999
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
54.4
796
4629
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
43.8
532
2784
JFA42
NOMESCO Finland
Endoscopic injection in colon
20.9
42.4
63
31
D12.7
ICD-10 Finland
Benign neoplasm: Rectosigmoid junction
9.8
40.3
83
88
N02BE01
ATC
paracetamol; systemic, rectal
2.3
39.8
1796
15443
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
39.7
608
3494
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.2
39.5
229
783
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
39.2
1041
7323
A02BC02
ATC
pantoprazole; systemic
1.9
38.4
1407
11024
D64.9
ICD-10 Finland
Anaemia, unspecified
2.6
38.2
309
1303
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.9
38.0
253
949
B01AB05
ATC
enoxaparin; parenteral
1.9
37.8
742
4674
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.6
37.6
312
1335
K63.5
ICD-10 Finland
Polyp of colon
7.6
31.0
74
101
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
6.1
30.5
85
144
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
30.4
333
1627
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
6.8
28.5
73
111
WX002
NOMESCO Finland
Sedation and analgesia
1.9
28.3
483
2832
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.6
28.3
218
888
JN4BD
NOMESCO Finland
Extensive body CT
2.2
27.6
306
1501
P01AB01
ATC
metronidazole; oral, rectal
1.7
27.2
782
5426
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.3
27.1
284
1354
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
6.6
25.8
67
104
K92.1
ICD-10 Finland
Melaena
2.9
25.1
163
598
N02AX02
ATC
tramadol; systemic, rectal
1.6
24.9
901
6622
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
2.8
24.8
169
638
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
11.8
24.0
44
38
J01DB01
ATC
cefalexin; oral
1.7
23.1
1605
13897
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
4.0
23.0
93
238
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
22.3
377
2179
JFA55
NOMESCO Finland
Other endoscopic procedure using diathermy or heat in colon
15.5
21.5
35
23
C07AB07
ATC
bisoprolol; oral
1.6
21.4
1062
8340
C10AA05
ATC
atorvastatin; oral
1.6
21.3
889
6685
S18
ICPC
Laceration/cut
1.6
21.1
899
6793
N03AX16
ATC
pregabalin; oral
1.7
21.0
499
3221
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
14.2
20.8
35
25
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
20.8
554
3692
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
20.6
580
3923
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
2.7
20.4
143
548
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
4.2
20.3
78
191
AA1AD
NOMESCO Finland
CT of head and brain
1.7
20.2
543
3626
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
20.0
554
3727
UJF34
NOMESCO Finland
Left colonoscopy
9.7
19.8
40
42
N06AX11
ATC
mirtazapine; oral
1.6
19.6
611
4243
L01BC06
ATC
capecitabine; oral
3.1
19.1
108
360
JFA45
NOMESCO Finland
Endoscopic contact coagulation in colon
8.0
19.0
43
55
C03CA01
ATC
furosemide; systemic
1.6
18.9
664
4743
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
18.9
366
2208
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.2
18.8
102
332
C20.90
ICD-10 Finland
Malignant tumor of the rectum without histology
4.8
18.7
62
131
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.1
18.5
234
1206
JFB30
NOMESCO Finland
Right hemicolectomy
5.0
18.4
59
120
WX110
NOMESCO Finland
Local anesthesy
1.5
18.2
1266
10560
K59.09
ICD-10 Finland
Constipation, unspecified
2.4
18.2
164
722
A10BA02
ATC
metformin; oral
1.6
18.1
624
4425
UJH02
NOMESCO Finland
Anoscopy
2.8
17.6
113
412
A02BC05
ATC
esomeprazole; systemic
1.5
17.5
797
6033
G47.3
ICD-10 Finland
Sleep apnoea
1.7
17.4
434
2819
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
5.7
17.2
49
87
JN4AD
NOMESCO Finland
Body CT examination
2.1
17.2
195
959
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
17.2
700
5154
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
9.8
16.7
33
34
C18.60
ICD-10 Finland
Malignant tumor of the descending colon without histology
27.8
16.5
22
8
103
Kela drug reimbursment
Diabetes, insulin-treated
1.6
16.4
590
4210
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
16.4
876
6836
D01
ICPC
Abdominal pain/cramps general
2.1
16.3
195
981
J01MA12
ATC
levofloxacin; systemic
1.7
16.3
400
2582
H02AB06
ATC
prednisolone; systemic
1.5
16.1
918
7248
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
16.1
357
2236
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
16.0
578
4120
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.6
15.7
120
486
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
15.6
1272
10787
C18.61
ICD-10 Finland
Malignant tumor of the colon descending invasive carcinoma
16.2
15.2
24
15
JFB43
NOMESCO Finland
Left hemicolectomy
7.6
15.2
35
47
XKD00
NOMESCO Finland
Uroflowmetry
1.7
15.2
399
2617
C05AA08
ATC
fluocortolone; rectal, topical
1.8
15.1
304
1843
SPAT1104
SPAT
Monitoring of emergency patient
2.2
15.1
164
791
JGA05
NOMESCO Finland
Endoscopic polypectomy in rectum
7.8
15.1
34
44
D11
ICPC
Diarrhoea
2.1
14.7
179
905
T90
ICPC
Diabetes non-insulin dependent
1.6
14.6
520
3685
A02BC03
ATC
lansoprazole; oral
1.5
14.6
588
4286
I84.9
ICD-10 Finland
Unspecified hemorrhoids without complication
2.4
14.5
121
513
130
Kela drug reimbursment
Malignant tumour
2.0
14.5
202
1080
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.0
14.5
83
282
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
14.5
432
2929
C18.21
ICD-10 Finland
Malignant tumor of the ascending colon invasive carcinoma
6.5
14.4
37
58
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
14.2
734
5639
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.3
14.2
128
567
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
14.1
174
885
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
14.0
188
991
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
14.0
167
840
R03AC02
ATC
salbutamol; inhalant
1.4
13.9
938
7584
M54.5
ICD-10 Finland
Low back pain
1.5
13.8
583
4279
A08
ICPC
Swelling
2.6
13.7
104
419
A02BC01
ATC
omeprazole; systemic
1.5
13.7
560
4081
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
13.7
600
4440
A06AD11
ATC
lactulose; oral
1.7
13.6
321
2038
21135
ICD-8 Finland
Benign neoplasm of other parts of digestive system, Coli descendentis
+∞
13.6
13
*
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
3.3
13.5
67
206
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
4.7
13.5
45
97
UJF92
NOMESCO Finland
Capsular endoscopy
3.8
13.5
57
154
D12.9
ICD-10 Finland
Benign neoplasm: Anus and anal canal
6.3
13.5
35
56
R51.80
ICD-10 Finland
Headache
1.8
13.5
236
1365
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
13.3
756
5897
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.7
13.3
90
339
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
13.3
224
1282
8140/3-C18.9
ICD-O-3
Adenocarcinoma, NOS, of colon, NOS
8.6
13.2
28
33
ZX120
NOMESCO Finland
Intravenous
1.9
13.1
199
1098
R4110
NOMESCO Finland
Physiotherapy
1.5
13.1
524
3795
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
13.0
356
2354
N03AX12
ATC
gabapentin; oral
1.7
12.8
302
1916
JFB31
NOMESCO Finland
Laparoscopic right hemicolectomy
4.3
12.8
47
112
N05CF01
ATC
zopiclone; oral
1.5
12.8
630
4764
J01DA01
ATC
[U] cefalexin; systemic
1.4
12.6
1148
9739
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
12.6
881
7128
I84.5
ICD-10 Finland
External hemorrhoids without complication
2.8
12.4
78
284
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.0
12.3
165
869
K29.3
ICD-10 Finland
Chronic superficial gastritis
2.6
12.3
89
352
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
12.2
270
1681
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.1
12.1
147
743
R06.0
ICD-10 Finland
Dyspnoea
1.5
12.0
505
3686
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
3.2
12.0
61
192
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
12.0
392
2705
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
12.0
322
2114
A10AE04
ATC
insulin glargine; parenteral
1.8
12.0
202
1155
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
12.0
184
1020
J01MA02
ATC
ciprofloxacin; systemic
1.4
11.9
765
6073
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
11.9
192
1082
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.3
11.8
43
102
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
11.8
427
3011
C10AA01
ATC
simvastatin; oral
1.4
11.8
963
7969
E0000UV
ATC
NA
1.4
11.8
684
5322
Z80.0
ICD-10 Finland
Family history of malignant neoplasm of digestive organs
8.4
11.8
25
30
ZXA00
NOMESCO Finland
Right side
1.5
11.8
557
4165
KMAK
NOMESCO Finland
NA
1.4
11.6
861
7006
SPAT1153
SPAT
Removal of sutures
1.4
11.5
660
5122
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
2.5
11.5
91
379
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
11.4
569
4292
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
11.4
230
1393
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
11.4
1206
10419
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
11.3
354
2413
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.4
11.3
648
5024
C08CA01
ATC
amlodipine; oral
1.4
11.2
772
6183
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
6.1
11.0
29
48
N05BA04
ATC
oxazepam; oral
1.5
11.0
433
3107
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.9
11.0
44
115
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
10.9
295
1939
A07EC02
ATC
mesalazine; oral, rectal
2.3
10.9
103
467
A02BA02
ATC
ranitidine; systemic
1.5
10.9
389
2736
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.7
10.8
221
1341
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
10.8
303
2010
R03BA02
ATC
budesonide; inhalant
1.6
10.8
300
1985
A98
ICPC
Health maint/preventive medicine
1.7
10.8
1868
17642
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
10.7
560
4254
SPAT1263
SPAT
Sampling
1.4
10.7
799
6479
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
10.6
482
3563
A10BB12
ATC
glimepiride; oral
1.8
10.6
171
963
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
10.6
650
5090
SPAT1254
SPAT
Administration of medicine
1.6
10.5
288
1897
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
10.5
255
1628
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.2
10.4
103
479
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
2.9
10.3
64
229
R53
ICD-10 Finland
Malaise and fatigue
1.5
10.3
357
2488
JFA52
NOMESCO Finland
Other endoscopic haemostatic procedure in colon
7.1
10.3
24
34
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.0
10.2
127
650
R4120
NOMESCO Finland
Occupational therapy
2.0
10.2
122
616
C20.99
ICD-10 Finland
Malignant tumor of the rectum other or unspecified histology
6.5
10.0
25
39
UJF02
NOMESCO Finland
Peroral enteroscopy
7.3
10.0
23
32
N06AX21
ATC
duloxetine; oral
1.8
10.0
178
1038
SPAT1301
SPAT
No procedures
1.4
10.0
617
4829
R02
ICPC
Shortness of breath/dyspnoea
1.7
9.9
235
1487
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
9.9
104
494
N06AX16
ATC
venlafaxine; oral
1.7
9.9
206
1257
J45.1
ICD-10 Finland
Nonallergic asthma
2.0
9.9
128
664
M04AA01
ATC
allopurinol; systemic
1.6
9.8
288
1931
SPAT1097
SPAT
Recording of ECG
1.5
9.8
312
2129
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
9.8
891
7427
A02BC04
ATC
rabeprazole; oral
1.9
9.8
153
854
UKC02
NOMESCO Finland
Cystoscopy
1.5
9.8
363
2569
M79.6
ICD-10 Finland
Pain in limb
1.4
9.7
638
5037
A10BH05
ATC
linagliptin; oral
2.1
9.7
114
570
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.9
9.7
57
200
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
5.1
9.7
29
57
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.6
9.7
272
1803
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.2
9.7
102
486
K29.7
ICD-10 Finland
Gastritis, unspecified
2.4
9.6
78
327
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
4.9
9.6
30
62
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
9.5
109
541
A10BH01
ATC
sitagliptin; oral
1.7
9.5
209
1295
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
3.2
9.5
47
147
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
9.4
99
475
JFB51
NOMESCO Finland
Other laparoscopic resection of colon
30.1
9.4
12
*
C18.50
ICD-10 Finland
Malignant tumor in flexural lienalis without histology
17.6
9.4
14
8
C18.00
ICD-10 Finland
Malignant tumor of the caecum without histology
5.1
9.4
28
55
J01CA04
ATC
amoxicillin; systemic
1.4
9.3
1453
13133
JN4CD
NOMESCO Finland
Very extensive body CT
2.2
9.3
93
436
M03BX02
ATC
tizanidine; oral
1.3
9.3
1058
9109
E66.8
ICD-10 Finland
Other obesity
2.2
9.2
88
404
R01AD09
ATC
mometasone; nasal
1.4
9.2
726
5896
D06
ICPC
Abdominal pain localized other
1.9
9.2
139
767
R50.9
ICD-10 Finland
Fever, unspecified
1.6
9.1
243
1589
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.7
9.0
173
1029
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
5.6
9.0
25
45
K62.1
ICD-10 Finland
Rectal polyp
3.9
9.0
35
90
A07EA02
ATC
hydrocortisone; rectal
3.0
9.0
49
165
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
8.9
243
1599
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
8.8
456
3442
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
8.8
97
475
N06AB04
ATC
citalopram; systemic
1.5
8.8
367
2658
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
8.8
310
2166
K55.2
ICD-10 Finland
Angiodysplasia of colon
5.4
8.7
25
47
JGB00
NOMESCO Finland
Partial proctectomy and colorectal or coloanal anastomosis
6.0
8.7
23
39
N06AB10
ATC
escitalopram; oral
1.5
8.7
279
1906
J01FF01
ATC
clindamycin; systemic
1.4
8.7
478
3647
J01AA02
ATC
doxycycline; systemic
1.4
8.7
1475
13415
M48.0
ICD-10 Finland
Spinal stenosis
1.6
8.6
259
1743
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
8.6
796
6613
C18.51
ICD-10 Finland
Malignant tumor of flexura hiealis invasive carcinoma
11.6
8.6
15
13
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.4
8.6
69
292
I84.1
ICD-10 Finland
Internal hemorrhoids with other complications
2.7
8.5
56
212
E11
ICD-10 Finland
Type 2 diabetes mellitus
1.5
8.5
317
2239
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.5
414
3088
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
8.5
253
1698
I50.9
ICD-10 Finland
Heart failure, unspecified
1.5
8.5
283
1951
A01
ICPC
Pain general/multiple sites
1.8
8.4
140
800
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
8.4
268
1830
N05AH04
ATC
quetiapine; oral
1.6
8.4
242
1615
R60.0
ICD-10 Finland
Localized oedema
1.6
8.3
222
1448
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
8.3
316
2239
R03BB04
ATC
tiotropium bromide; inhalant
1.6
8.3
211
1363
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
2.1
8.3
88
424
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
8.3
359
2614
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
8.3
359
2616
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
8.3
1643
15253
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
8.3
114
611
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.2
8.2
81
378
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
8.2
113
601
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.9
8.1
115
621
B01AA03
ATC
warfarin; systemic
1.4
8.1
429
3242
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.6
8.1
227
1503
N05CF02
ATC
zolpidem; oral
1.5
8.1
284
1978
8140/3-C18.6
ICD-O-3
Adenocarcinoma, NOS, of descending colon
17.2
8.1
12
7
X58
ICD-10 Finland
Exposure to other specified factors
1.6
8.1
225
1485
SPAT1008
SPAT
Photography of fundus of the eye or interpretation of photograph
2.2
8.0
81
382
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
8.0
302
2138
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.7
8.0
175
1088
B01AC04
ATC
clopidogrel; oral
1.5
8.0
342
2486
A46
ICD-10 Finland
Erysipelas
1.5
7.9
285
1997
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.9
324
2332
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.4
7.9
62
260
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.8
7.9
140
814
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.8
1041
9066
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
7.8
701
5770
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
6.1
7.8
20
33
Z71.8
ICD-10 Finland
Other specified counselling
1.4
7.8
379
2819
J01FA09
ATC
clarithromycin; systemic
1.4
7.8
499
3896
R19.4
ICD-10 Finland
Change in bowel habit
2.6
7.8
52
200
A04
ICPC
Weakness/tiredness general
1.6
7.8
219
1451
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.8
450
3458
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.8
7.8
130
742
K02.1
ICD-10 Finland
Caries of dentine
1.3
7.7
906
7745
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.6
7.7
54
213
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.4
7.7
63
269
D16
ICPC
Rectal bleeding
2.8
7.7
47
172
8140/3-C18.2
ICD-O-3
Adenocarcinoma, NOS, of ascending colon
4.4
7.6
26
60
SPAT1262
SPAT
Handing over of treatment supplies
1.4
7.6
361
2671
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.4
7.6
489
3819
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.8
7.6
118
660
A03CA02
ATC
clidinium and psycholeptics; oral
1.8
7.6
118
660
TJX00
NOMESCO Finland
Punkture or biopsy in gastrointestinal endoscopy
25.1
7.6
10
*
L16
ICPC
Ankle symptom/complaint
1.7
7.5
164
1013
K30
ICD-10 Finland
Functional dyspepsia
1.6
7.5
174
1097
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
7.5
494
3875
K51.5
ICD-10 Finland
Left sided colitis
2.8
7.5
45
163
K59.0
ICD-10 Finland
Constipation
1.8
7.4
115
643
R01AD08
ATC
fluticasone; nasal
1.4
7.4
446
3443
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.6
7.4
212
1411
C18.41
ICD-10 Finland
Malignant tumor of the transverse colon invasive carcinoma
6.0
7.4
19
32
205
Kela drug reimbursment
Chronic hypertension
1.3
7.3
602
4885
C20.92
ICD-10 Finland
Malignant tumor of the rectum carcinoma of the adenoma
4.7
7.3
23
49
D12.1
ICD-10 Finland
Benign neoplasm: Appendix
8.4
7.3
15
18
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.8
7.3
121
690
C03DA01
ATC
spironolactone; oral
1.6
7.3
211
1406
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
7.3
306
2214
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.2
7.3
69
317
K92.0
ICD-10 Finland
Haematemesis
2.5
7.3
52
208
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
6.8
7.3
17
25
K50.8
ICD-10 Finland
Other Crohn disease
3.9
7.3
28
73
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
7.2
551
4418
R03AK07
ATC
formoterol and budesonide; inhalant
1.4
7.2
305
2205
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.2
180
1156
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.5
7.2
294
2112
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.6
7.2
189
1232
R4190
NOMESCO Finland
Nutritional therapy
2.4
7.2
58
248
R03DC03
ATC
montelukast; oral
1.5
7.1
241
1665
A07AA02
ATC
nystatin; oral
1.8
7.1
118
674
J02AC01
ATC
fluconazole; systemic
1.3
7.1
592
4807
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.3
7.1
750
6301
A06AC51
ATC
ispaghula, combinations; systemic
1.9
7.1
93
490
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
7.1
401
3060
XCK10
NOMESCO Finland
Photography of fundus of eye
1.6
7.1
197
1300
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
2.2
7.1
68
316
D37.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Rectum
3.4
7.0
31
91
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.5
7.0
53
219
JHB00
NOMESCO Finland
Hemorrhoidectomy
2.2
7.0
65
298
A04.8
ICD-10 Finland
Other specified bacterial intestinal infections
3.1
7.0
35
113
K51.8
ICD-10 Finland
Other ulcerative colitis
3.7
7.0
28
76
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
6.9
916
7925
H02AB04
ATC
methylprednisolone; systemic
1.5
6.9
256
1808
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
6.9
561
4541
J01MA14
ATC
moxifloxacin; systemic
1.6
6.9
164
1045
K64.0
ICD-10 Finland
First degree haemorrhoids
3.2
6.9
34
109
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
6.8
86
445
D02AE01
ATC
carbamide; topical
1.8
6.8
120
697
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
6.8
111
631
D01AC02
ATC
miconazole; topical
1.7
6.8
149
928
SPAT1216
SPAT
Assessment of functional ability
1.4
6.8
303
2214
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
4.5
6.8
22
49
L17
ICPC
Foot/toe symptom/complaint
1.4
6.7
453
3555
D18
ICPC
Change in faeces/bowel movements
2.6
6.7
47
184
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.6
6.7
167
1075
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
2.4
6.7
52
219
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
3.6
6.7
28
79
K29.6
ICD-10 Finland
Other gastritis
3.2
6.6
32
101
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.9
6.6
87
461
N05CD07
ATC
temazepam; oral
1.5
6.6
229
1593
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.9
6.6
38
133
E66.00
ICD-10 Finland
Metabolic syndrome
1.9
6.6
98
539
Z97.4
ICD-10 Finland
Presence of external hearing-aid
1.8
6.6
100
555
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
6.6
203
1376
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.5
6.6
47
189
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
6.5
558
4537
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
6.5
915
7947
A07EA06
ATC
budesonide; oral, local oral
2.3
6.5
58
258
-60
ICPC
Result test/procedure
1.8
6.5
114
662
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
6.9
6.5
15
22
3AC01
NOMESCO Finland
NA
3.7
6.5
26
71
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.6
6.5
181
1197
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.0
6.5
75
378
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.9
6.4
93
507
D02
ICPC
Abdominal pain epigastric
1.9
6.4
93
507
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
1.8
6.4
110
636
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.7
6.4
117
691
A02BD07
ATC
lansoprazole, amoxicillin and clarithromycin; systemic
1.9
6.4
95
524
B82
ICPC
Anaemia other/unspecified
2.3
6.4
53
231
SPAT1101
SPAT
Orthostatic test
1.9
6.4
91
495
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
1.7
6.4
115
676
C07AA05
ATC
propranolol; systemic
1.4
6.4
290
2126
R31
ICD-10 Finland
Unspecified haematuria
1.5
6.4
209
1433
A11
ICPC
Chest pain NOS
1.6
6.4
148
937
JAH01
NOMESCO Finland
Laparoscopy
2.1
6.3
67
325
-1
NOMESCO Finland
NA
1.3
6.3
495
3976
N02AA05
ATC
oxycodone; systemic
1.4
6.3
285
2088
J01MA06
ATC
norfloxacin; oral
1.5
6.3
228
1598
EP1AE
NOMESCO Finland
Neck ultrasound examination
1.8
6.3
94
520
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.7
6.3
124
747
M10.9
ICD-10 Finland
Gout, unspecified
1.6
6.3
142
889
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
6.3
179
1191
-
ICD-10 Finland
NA
2.3
6.3
52
227
R07.3
ICD-10 Finland
Other chest pain
1.6
6.3
173
1144
I78.8
ICD-10 Finland
Other diseases of capillaries
7.0
6.2
14
20
C10AC01
ATC
colestyramine; oral
2.3
6.2
51
221
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.1
6.2
62
295
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.7
6.2
127
777
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
6.2
249
1786
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.2
290
2138
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.9
6.2
85
457
JG1CG
NOMESCO Finland
Extensive MRI of rectum
4.5
6.2
20
45
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.7
6.1
109
639
R33
ICD-10 Finland
Retention of urine
1.6
6.1
161
1052
XF404
NOMESCO Finland
Ambulatory ECG
1.5
6.1
183
1229
WX892
NOMESCO Finland
Monitored bed care
1.6
6.1
145
922
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.0
6.1
78
407
N06AB06
ATC
sertraline; oral
1.6
6.1
151
972
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
6.0
207
1437
H25.8
ICD-10 Finland
Other senile cataract
1.5
6.0
225
1588
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
1.5
6.0
201
1384
J01FA10
ATC
azithromycin; systemic
1.3
6.0
902
7876
D07AB02
ATC
hydrocortisone butyrate; topical
1.3
6.0
458
3661
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
2.4
6.0
46
191

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
918
2222
6.11
307.65
1.6
1.3
—
—
—
0
0
573
2418
2.81
91.07
5.3
4.1
5.8
24.7
ug/l
3.38
483
2001
1424
9352
2.31
83.30
6.2
4.9
35.0
34.9
g/l
0.07
1360
8677
1567
10989
2.26
74.32
7.3
6.4
11.5
12.0
umol/l
0.71
1498
10443
948
5456
2.23
73.96
2.8
2.2
3.4
3.0
mg/l
3.69
864
4617
1985
15854
2.55
62.78
10.1
7.8
80.7
79.7
u/l
0.35
1914
14911
1881
14842
2.30
58.22
5.1
4.2
14.9
13.4
mm/h
3.30
1764
13655
563
2895
2.24
55.24
1.3
1.3
—
—
—
0
0
1179
7960
1.96
54.82
4.0
2.8
134.6
154.2
ug/l
2.19
1120
7255
1288
8985
1.95
54.08
2.4
2.1
92.9
93.6
pmol/l
0.18
751
4684
430
1989
2.42
53.89
2.3
2.2
149.5
157.2
ug/g
0.17
346
1566
1564
11680
2.00
53.43
10.1
9.0
4.4
4.2
e9/l
1.77
1392
10165
1022
6638
1.95
52.64
3.0
2.6
—
—
—
0
0
1470
10787
1.96
52.36
9.0
6.9
1.2
1.2
mmol/l
1.86
1362
9059
628
3439
2.12
52.15
3.6
2.5
11.4
12.7
umol/l
5.35
591
3191
1007
6536
1.94
51.73
3.2
2.6
61.6
58.2
u/l
0.61
941
6017
591
3184
2.14
51.07
3.5
2.5
2.3
2.3
g/l
1.64
558
2957
565
3011
2.15
50.09
3.6
2.6
20.0
22.7
%
4.89
493
2579
1377
10013
1.90
48.94
6.8
5.7
0.0
0.0
e9/l
0.87
1209
8568
1174
8121
1.88
48.69
2.6
2.2
—
—
—
0
0
829
5132
1.95
48.21
2.8
2.5
—
—
—
0
0
1369
9966
1.89
48.15
6.8
5.7
0.6
0.6
e9/l
1.08
1205
8515
1404
10333
1.88
47.39
7.0
5.9
0.2
0.2
e9/l
0.20
1247
8971
1356
9879
1.87
47.16
7.8
6.1
1.2
1.2
mmol/l
0.97
1275
8910
1611
12452
1.92
46.01
6.2
5.0
7.0
6.8
mmol/l
1.74
1545
11755
1384
10203
1.86
45.76
6.9
5.8
1.9
1.9
e9/l
0.16
1217
8885
1696
13371
1.94
45.13
5.8
4.7
317.3
1754.3
e6/l
—
6
218
1268
9205
1.81
42.97
11.6
10.4
1.3
1.3
inr
0.20
246
2561
711
4332
1.92
42.28
1.9
1.8
1109.7
1189.9
nmol/l
1.17
571
3234
625
3727
1.92
39.18
1.3
1.2
2.3
1.4
u/ml
0.37
164
964
2199
19479
2.80
38.62
23.8
16.2
26.1
26.1
mg/l
0.04
1924
15721
1711
13827
1.85
38.40
5.6
4.5
—
—
—
0
0
403
2093
2.12
37.10
9.4
7.3
10.9
10.5
mmol/l
0.46
391
1990
1285
9626
1.73
36.67
4.6
4.2
—
—
—
0
0
780
5124
1.78
35.11
7.6
6.7
—
—
—
0
0
794
5276
1.76
34.15
5.4
4.1
86.1
86.5
%
0.18
771
5154
560
3361
1.87
33.71
1.4
1.5
2.6
2.6
g/l
0.00
316
1988
1139
8381
1.69
33.61
4.8
3.9
39.2
110.1
ng/l
0.78
873
6298
508
2962
1.91
33.40
7.7
5.7
1.0
1.0
mmol/l
0.17
484
2748
500
2906
1.91
33.17
7.0
6.8
104.9
104.2
mmol/l
2.25
491
2830
722
4719
1.76
32.59
5.2
3.7
—
—
—
0
0
331
1672
2.14
32.48
4.8
3.8
107.0
93.6
ng/l
1.49
304
1444
252
1152
2.33
31.52
2.7
2.4
—
—
—
0
0
982
7036
1.68
31.37
6.2
5.7
—
—
—
0
0
1512
12138
1.68
30.77
4.3
3.2
61.9
55.0
u/l
1.39
1411
11129
1235
9440
1.64
30.23
7.2
5.9
59.1
58.0
%
2.27
1157
8792
1232
9416
1.64
30.13
7.6
6.2
8.8
8.9
%
0.70
1163
8775
961
6926
1.65
29.48
3.6
3.1
1690.8
1540.2
ng/l
0.40
865
5982
888
6275
1.66
29.41
4.9
4.4
—
—
—
0
0
1223
9383
1.63
29.03
7.3
6.0
2.8
2.9
%
0.47
1157
8705
1091
8142
1.63
28.95
2.6
2.2
77.7
78.7
nmol/l
0.53
1009
7152
1025
7539
1.63
28.80
5.0
3.5
—
5.8
—
0
6
585
3709
1.77
28.77
3.2
2.9
1.0
1.2
e6/l
0.76
352
2166
991
7236
1.64
28.62
3.7
3.4
2.4
2.4
mmol/l
0.03
868
6250
1741
14634
1.72
28.54
4.6
3.9
15.1
15.0
pmol/l
1.01
1614
13088
1241
9591
1.62
28.31
7.4
6.1
25.7
26.7
%
2.50
1159
8885
2259
20774
2.88
27.76
28.3
19.2
86.8
81.5
umol/l
5.81
2259
20768
1188
9137
1.60
27.24
7.2
6.0
0.7
0.7
%
0.76
1122
8493
809
5668
1.65
27.19
3.3
2.8
3462.7
5551.2
umol/l
0.90
711
4862
2242
20590
2.66
26.70
28.6
19.1
139.7
139.7
mmol/l
0.19
2233
20068
451
2699
1.83
26.70
2.4
2.5
1.8
1.8
%
0.11
411
2376
377
2135
1.91
26.54
5.4
3.5
2.0
2.0
mmol/l
0.06
308
1706
2016
17801
1.89
26.47
5.8
4.7
2.0
2.1
mu/l
0.09
1888
16019
377
2139
1.91
26.38
5.4
3.5
5.8
5.8
kpa
0.15
370
2075
964
7113
1.60
25.90
4.5
4.0
10.9
8.8
mg/mmol
0.67
686
4499
2242
20636
2.61
25.72
28.8
19.3
4.0
4.0
mmol/l
1.46
2232
20094
936
6887
1.59
25.28
3.7
3.2
7.4
7.4
mmol/l
0.12
823
5706
920
6747
1.59
25.16
3.8
3.3
331.7
282.9
mg/l
0.14
646
4284
344
1927
1.92
24.93
8.0
8.2
—
—
—
0
0
445
2705
1.79
24.85
6.8
7.2
5.0
5.1
kpa
0.62
423
2576
499
3136
1.75
24.84
34.3
27.2
1.5
1.4
inr
0.72
46
438
445
2706
1.79
24.81
6.8
7.2
12.1
12.0
kpa
0.19
420
2579
445
2708
1.79
24.75
7.0
7.2
0.9
1.1
mmol/l
0.37
338
2114
2192
20032
2.26
24.65
22.5
15.4
—
—
—
0
0
905
6647
1.58
24.39
2.3
2.2
212.0
230.4
u/l
0.20
867
6221
394
2332
1.83
23.96
2.9
2.8
8.8
8.7
umol/l
0.01
348
2056
827
5967
1.59
23.93
3.9
3.3
0.5
0.5
e6/l
0.28
632
4570
220
1067
2.17
23.67
3.8
2.5
1.3
1.1
%
1.45
220
1057
751
5312
1.61
23.55
1.7
1.6
20.1
20.4
nmol/l
0.19
672
4470
1240
9830
1.55
23.54
5.2
3.8
0.0
0.0
estimate
0.80
150
1789
633
4294
1.65
23.52
5.8
4.2
1.0
1.0
kg/l
0.07
113
640
362
2101
1.85
23.41
2.8
2.1
0.2
0.2
g/l
0.74
344
1951
2243
20769
2.50
23.22
15.3
11.2
25.9
26.0
u/l
0.10
2204
19958
986
7453
1.55
23.05
4.6
3.8
69.0
115.7
e6/l
1.50
719
5448
337
1922
1.88
23.00
2.8
2.4
34.1
38.9
u/l
0.68
286
1648
2068
18624
1.87
22.52
8.3
6.4
41.4
40.6
mmol/mol
3.79
1959
17022
312
1748
1.90
22.47
4.4
2.9
4.4
4.5
kpa
0.41
305
1691
402
2446
1.78
22.16
7.1
7.5
95.5
95.5
%
0.03
389
2350
606
4122
1.63
22.05
3.7
3.1
2.5
2.5
mmol/l
1.15
529
3634
212
1043
2.13
21.96
3.5
2.4
0.7
0.6
%
0.27
205
993
527
3465
1.67
21.89
3.5
3.1
2.4
2.0
e6/l
0.42
300
1932
790
5754
1.56
21.39
3.9
3.2
—
—
—
0
0
1213
9692
1.52
21.35
5.1
3.8
0.0
0.0
estimate
0.00
150
1830
874
6526
1.54
21.07
4.0
3.4
66.2
91.5
e6/l
0.29
678
5099
862
6437
1.53
20.67
3.8
3.3
—
—
—
0
0
321
1862
1.84
20.65
4.5
3.5
—
—
—
0
0
220
1124
2.06
20.60
1.6
1.7
1.5
1.5
g/l
0.06
195
964
271
1492
1.92
20.50
7.4
9.0
93.7
93.9
%
0.16
271
1484
212
1075
2.07
20.25
5.5
3.7
24.3
24.1
mmol/l
0.36
190
952
2155
19815
1.97
19.91
6.3
5.4
2.5
2.7
mmol/l
8.73
2035
17994
343
2056
1.78
19.74
2.4
2.5
71.2
69.5
e9/l
0.41
280
1572
2116
19352
1.87
19.72
6.1
5.0
6.2
6.1
mmol/l
7.40
1999
17405
1205
9715
1.49
19.64
6.9
5.1
0.0
0.0
estimate
0.00
157
1861
339
2033
1.78
19.46
6.2
7.0
1.4
1.4
mmol/l
0.31
326
1964
2271
21333
2.56
19.43
36.7
23.9
244.8
243.6
e9/l
0.40
2254
20743
365
2238
1.75
19.40
7.7
8.0
117.9
121.3
g/l
2.44
352
2156
141
617
2.37
19.36
1.5
1.4
235.7
271.3
ug/g
1.46
98
367
2271
21338
2.55
19.33
36.5
23.7
30.4
30.5
pg
1.85
2262
20979
2271
21338
2.55
19.33
36.5
23.8
91.7
91.6
fl
0.38
2263
20981
2271
21340
2.55
19.29
36.7
23.8
4.4
4.4
e12/l
9.38
2252
20676
2271
21342
2.55
19.25
36.7
23.9
7.0
6.8
e9/l
5.64
2251
20678
2271
21343
2.55
19.23
36.9
24.0
131.6
134.6
g/l
15.66
2263
20987
133
570
2.41
19.13
1.3
1.2
—
—
—
0
0
610
4292
1.57
18.79
2.1
1.8
1.2
1.4
mg/l
0.61
502
3359
2046
18584
1.74
18.74
5.0
4.2
1.4
1.3
mmol/l
6.85
1923
16699
528
3599
1.60
18.61
3.7
3.2
0.8
0.8
mmol/l
0.46
493
3368
342
2089
1.74
18.36
2.8
2.5
6.7
7.4
ug/l
0.18
298
1837
41
92
4.52
17.06
5.6
3.8
—
—
—
0
0
378
2418
1.67
17.05
1.3
1.3
533.3
519.6
titre
0.06
93
540
595
4268
1.53
16.46
3.4
2.8
561.1
551.9
mosm/kgh2o
0.41
504
3633
233
1314
1.86
16.26
1.2
1.2
—
—
—
0
0
834
6419
1.46
16.25
5.7
4.1
7.4
7.4
ph
1.47
89
1244
2084
19198
1.71
15.93
5.4
4.7
1.4
1.4
mmol/l
7.74
1971
17402
2097
19353
1.73
15.89
5.6
4.8
4.4
4.5
mmol/l
9.23
1987
17683
42
102
4.17
15.83
5.5
3.7
—
—
—
0
0
626
4588
1.50
15.48
2.9
2.7
4.2
5.0
e6/l
0.59
525
4045
842
6549
1.44
15.29
5.0
4.1
—
—
—
0
0
370
2416
1.63
15.28
2.0
1.8
—
—
—
0
0
448
3063
1.57
15.25
2.3
2.1
—
—
—
0
0
266
1596
1.75
15.08
5.8
4.6
—
—
—
0
0
117
527
2.28
15.06
2.0
1.7
—
—
—
0
0
193
1058
1.90
14.69
3.8
3.9
—
—
—
0
0
77
289
2.72
14.61
3.1
2.3
5.6
204.3
u/ml
0.78
77
281
158
814
2.01
14.42
2.4
2.3
473.0
784.3
ug/l
0.54
146
769
310
1981
1.65
13.88
2.4
2.7
65.6
66.4
g/l
1.10
276
1811
407
2790
1.55
13.56
12.1
7.4
—
—
—
0
0
173
940
1.91
13.53
5.8
4.4
—
—
—
0
0
486
3465
1.51
13.49
2.1
2.0
30.3
30.0
s
0.38
472
3359
162
862
1.94
13.48
3.7
3.3
186.0
5690.1
u/ml
1.01
138
733
1638
14510
1.42
13.27
4.9
4.2
—
—
—
0
0
441
3102
1.52
13.01
1.3
1.2
24.9
38.1
iu/ml
2.76
134
976
580
4320
1.45
12.84
4.6
4.0
222.6
628.7
ng/l
1.22
483
3622
240
1469
1.71
12.62
4.0
3.8
5.1
5.2
kpa
0.22
220
1360
359
2429
1.56
12.62
1.6
1.4
—
—
—
0
0
155
836
1.91
12.40
4.8
3.7
1.3
1.4
mmol/l
0.47
150
822
423
2977
1.51
12.40
1.3
1.2
16.8
12.4
u/ml
0.40
154
1101
212
1272
1.73
11.97
7.2
9.4
24.0
24.4
mmol/l
1.10
196
1191
235
1451
1.69
11.95
4.0
3.8
7.4
7.4
ph
0.53
21
185
160
887
1.86
11.77
4.0
4.1
24.7
24.9
mmol/l
0.35
144
823
175
1001
1.81
11.64
1.3
1.3
—
—
—
0
0
331
2242
1.55
11.52
4.6
4.5
—
—
—
0
0
1862
17032
1.44
11.42
25.9
17.6
37.7
39.2
%
6.27
1238
11093
263
1697
1.62
11.25
1.9
1.5
—
—
—
0
0
234
1468
1.66
11.19
9.2
6.7
24.3
24.5
mmol/l
0.44
221
1369
1732
15689
1.39
10.87
33.3
21.4
330.0
332.0
g/l
15.08
1725
15563
258
1672
1.61
10.83
2.3
2.5
—
—
—
0
0
68
282
2.45
10.62
1.5
1.6
0.7
0.9
g/l
1.00
59
212
233
1485
1.63
10.47
1.4
1.4
—
—
—
0
0
284
1921
1.54
9.89
1.5
1.4
—
—
—
0
0
265
1784
1.55
9.42
1.8
1.5
—
—
—
0
0
100
512
2.00
9.36
3.5
3.3
73.6
876.7
u/ml
0.96
92
477
119
649
1.88
9.26
1.8
1.6
—
—
—
0
0
200
1271
1.63
9.09
1.2
1.3
—
—
—
0
0
29
84
3.48
8.64
2.6
2.4
—
—
—
0
0
93
478
1.98
8.64
4.0
2.7
—
—
—
0
0
667
5378
1.33
8.63
5.6
4.1
0.0
0.0
estimate
0.69
154
1749
225
1490
1.56
8.60
2.6
2.8
10.4
10.7
g/l
0.42
213
1355
115
636
1.85
8.58
3.9
3.5
—
—
—
0
0
262
1797
1.51
8.54
2.7
2.2
369.7
368.6
nmol/l
0.03
239
1630
1026
8787
1.30
8.53
11.7
10.1
0.0
0.0
e9/l
0.33
853
7171
250
1699
1.53
8.50
1.5
1.5
—
—
—
0
0
196
1260
1.61
8.50
2.6
2.5
29.9
22.8
au/ml
—
6
44
296
2088
1.48
8.41
1.9
1.5
—
—
—
0
0
99
526
1.92
8.36
1.5
1.4
0.2
0.2
g/l
0.06
93
501
179
1133
1.63
8.27
1.4
1.3
28.3
52.8
au/ml
—
9
49
588
4696
1.34
8.03
1.7
1.7
39689159.0
25515155.1
pmol/l
0.26
514
3837
144
877
1.68
7.74
2.1
2.5
10.0
10.4
g/l
0.52
114
752
32
106
3.05
7.74
1.8
1.4
4.0
2.4
u/field
0.41
20
80
158
994
1.63
7.50
2.0
1.9
1.6
2.4
ug/l
0.72
143
876
365
2734
1.40
7.45
1.4
1.3
—
—
—
0
0
40
154
2.62
7.37
1.5
1.2
327.7
365.4
nmol/l
0.56
35
128
193
1279
1.55
7.36
9.4
9.8
—
—
—
0
0
90
486
1.89
7.28
3.3
2.8
32.7
37.5
umol/l
0.80
71
409
43
173
2.51
7.26
1.3
1.4
2.8
3.0
g/l
0.28
34
119
43
173
2.51
7.26
1.3
1.4
0.5
0.4
g/l
0.39
33
119
43
173
2.51
7.26
1.3
1.4
7.4
7.1
g/l
0.20
34
118
180
1179
1.57
7.23
1.9
1.8
1.5
1.5
g/l
0.09
164
1075
29
95
3.08
7.16
2.2
2.5
704.0
1411.6
u/ml
1.53
29
95
497
6152
0.76
6.90
3.2
3.2
—
—
—
0
0
1000
8698
1.26
6.83
5.6
5.2
2.9
3.6
ug/l
0.38
905
7732
125
759
1.68
6.83
3.6
3.1
0.5
0.3
g/l
0.77
61
304
62
302
2.08
6.74
1.6
1.4
—
—
—
0
0
91
511
1.81
6.54
1.3
1.2
171.2
95.1
titre
—
8
35
125
768
1.66
6.54
2.7
3.5
1.3
1.7
ratio
0.59
12
55
128
792
1.65
6.52
2.7
3.5
54.9
57.2
mg/l
0.08
115
648
52
240
2.19
6.49
1.3
1.3
—
—
—
0
0
55
260
2.14
6.47
1.5
2.0
—
—
—
0
0
91
517
1.79
6.31
1.4
1.6
—
—
—
0
0
127
793
1.64
6.25
2.7
3.5
36.6
74.5
mg/l
1.34
112
651
92
528
1.77
6.17
3.3
3.2
0.8
0.8
nmol/l
0.66
76
408
99
584
1.73
6.04
2.6
2.3
196.6
91.2
ug/min
1.16
61
351
22
68
3.26
6.00
2.5
2.4
—
—
—
0
0
45
203
2.24
5.96
1.1
1.1
—
—
—
0
0
118
738
1.63
5.79
2.1
2.3
36.2
37.5
g/l
1.21
94
641
40
176
2.29
5.63
1.3
1.4
—
—
—
0
0
18
51
3.55
5.60
8.2
4.2
—
—
—
0
0
55
279
1.99
5.42
3.2
2.5
—
—
—
0
0
56
287
1.97
5.37
3.1
2.5
4.1
4.1
mmol/l
0.05
56
282
56
287
1.97
5.37
3.1
2.5
106.3
105.4
mmol/l
0.85
56
282
106
660
1.63
5.32
1.3
1.2
1.6
0.7
u/ml
—
8
59
137
908
1.54
5.29
1.2
1.2
—
—
—
0
0
45
214
2.12
5.27
4.1
3.5
—
—
—
0
0
160
1101
1.49
5.18
1.6
1.4
—
—
—
0
0
188
1340
1.44
5.08
2.8
3.3
4.7
4.3
e9/l
0.72
136
995
113
1715
0.64
5.06
5.8
4.1
—
—
—
0
0
15
41
3.68
4.92
1.1
1.0
—
—
—
0
0
56
297
1.91
4.89
1.7
1.4
119.8
123.2
u/ml
0.08
11
54
74
430
1.74
4.83
2.8
1.5
0.8
0.8
nmol/l
0.10
59
351
88
539
1.66
4.75
1.8
1.7
12492.3
15045.9
e6/l
0.22
59
388
34
152
2.25
4.66
1.6
2.2
6.9
7.2
mmol/l
0.44
20
96
87
535
1.65
4.63
4.1
2.8
1.8
1.7
mg/l
0.54
76
484
146
1018
1.46
4.46
1.3
1.3
111.2
208.6
u/ml
3.77
134
932
50
264
1.91
4.46
1.3
1.4
175.9
59.3
mu/l
0.78
42
231
32
143
2.25
4.41
1.3
1.4
—
—
—
0
0
38
183
2.09
4.37
2.0
2.1
3.4
2.3
u/field
0.20
19
66
264
2055
1.32
4.17
3.3
3.1
228.8
215.6
ng/l
0.23
245
1881
28
123
2.29
4.03
3.8
3.7
—
—
—
0
0
32
149
2.16
4.02
1.1
1.2
134.0
117.8
titre
—
5
27
140
989
1.44
4.02
3.0
2.7
—
—
—
0
0
488
4123
1.23
3.94
5.7
4.6
—
—
—
0
0
45
240
1.89
3.93
1.3
1.4
397.3
275.6
pmol/l
0.78
37
182
132
931
1.44
3.84
2.1
2.0
—
—
—
0
0
59
346
1.72
3.80
1.2
1.4
—
—
—
0
0
59
346
1.72
3.80
1.7
1.3
—
—
—
0
0
244
1907
1.31
3.76
1.6
1.5
—
—
—
0
0
91
598
1.54
3.74
2.4
3.6
—
—
—
0
0
62
1002
0.61
3.71
1.5
1.4
—
—
—
0
0
26
115
2.27
3.71
6.1
16.7
—
—
—
0
0
160
1179
1.38
3.64
2.7
2.8
0.1
0.3
e6/l
1.60
154
1157
21
85
2.48
3.63
6.9
7.4
53.1
63.9
mg/l
0.82
15
64
21
85
2.48
3.63
4.1
2.3
776.3
746.5
e6/l
0.03
14
70
1659
15712
1.19
3.54
29.3
19.8
14.2
13.8
%
14.91
1642
15348
108
748
1.47
3.48
1.9
2.0
23.0
21.7
s
0.50
93
679
19
75
2.55
3.46
3.9
2.2
933.8
25107.4
e6/l
0.56
11
47
51
296
1.74
3.44
1.3
1.2
—
—
—
0
0
64
396
1.63
3.41
1.6
1.6
—
—
—
0
0
57
343
1.68
3.38
1.4
1.5
—
—
—
0
0
130
940
1.41
3.33
7.4
5.2
0.9
0.9
%
1.18
121
878
42
233
1.82
3.30
1.5
1.3
—
—
nmol/l
—
0
0
19
78
2.45
3.21
1.3
1.4
4.0
3.2
mmol/l
0.22
19
68
18
72
2.51
3.21
2.7
1.9
—
—
—
0
0
45
259
1.75
3.15
1.3
1.2
—
—
—
0
0
130
952
1.39
3.11
6.7
5.1
1.8
1.6
%
0.98
122
887
33
173
1.92
3.09
2.6
1.8
10.4
10.9
%
0.30
33
173
43
246
1.76
3.08
1.4
1.3
—
—
—
0
0
30
153
1.97
3.04
1.5
1.4
30.7
33.3
u/l
0.14
24
120
69
451
1.55
2.97
1.2
1.2
—
—
—
0
0
39
220
1.79
2.94
1.5
1.2
158.8
63.6
u/ml
—
5
9
569
5007
1.18
2.92
3.3
3.2
0.8
0.8
ug/l
0.17
430
3487
37
206
1.81
2.91
1.7
2.0
1.0
1.6
g/24h
—
5
7
17
70
2.44
2.88
1.7
1.7
—
—
—
0
0
71
471
1.52
2.87
1.4
1.2
1.5
3.7
u/ml
—
7
46
30
157
1.92
2.85
1.2
1.2
—
—
—
0
0
37
209
1.78
2.79
1.5
2.1
—
—
—
0
0
14
54
2.60
2.70
1.9
1.5
—
—
—
0
0
30
161
1.87
2.66
2.3
2.3
—
—
—
0
0
26
481
0.54
2.65
6.1
3.7
32.5
28.7
mg/l
0.13
15
295
50
312
1.62
2.65
2.8
2.4
—
—
—
0
0
141
1077
1.33
2.63
2.9
3.2
4.2
4.4
pmol/l
0.90
130
932
43
259
1.67
2.61
1.1
1.2
2.5
5.5
u/ml
1.44
17
113
18
80
2.26
2.60
1.5
1.2
8.0
16.9
umol/l
0.46
13
44
25
127
1.98
2.60
2.0
1.5
1.0
1.0
g/l
0.13
25
127
90
641
1.42
2.58
1.5
1.4
—
—
—
0
0
74
508
1.47
2.57
2.9
2.2
126.8
128.6
g/l
0.18
44
375
38
223
1.72
2.54
2.0
1.4
—
—
—
0
0
14
56
2.51
2.53
1.1
1.1
—
—
—
0
0
31
173
1.80
2.46
1.2
1.3
—
30.6
—
0
10
83
590
1.42
2.42
6.5
4.4
—
—
—
0
0
61
409
1.50
2.40
1.5
1.3
72.0
61.0
mmol/l
1.19
46
327
31
175
1.78
2.38
2.5
1.5
—
—
—
0
0
66
451
1.48
2.37
3.7
2.9
—
—
—
0
0
38
228
1.68
2.37
2.5
1.5
—
—
—
0
0
22
111
1.99
2.35
3.0
1.8
—
—
—
0
0
47
299
1.58
2.34
1.3
1.2
326.5
282.2
u/ml
0.36
37
178
38
229
1.67
2.33
2.6
1.5
—
—
—
0
0
14
59
2.38
2.29
1.0
1.0
—
—
—
0
0
36
215
1.68
2.29
2.6
1.6
—
—
—
0
0
21
106
1.99
2.25
1.0
1.1
—
—
—
0
0
42
263
1.61
2.24
1.8
1.6
54.3
63.6
%
0.68
27
165
566
5075
1.15
2.23
1.3
1.3
—
—
—
0
0
16
73
2.20
2.21
1.3
1.2
33.1
39.7
g/l
—
8
40
38
234
1.63
2.17
1.5
1.5
—
—
—
0
0
38
234
1.63
2.17
1.5
1.5
—
—
—
0
0
38
234
1.63
2.17
1.5
1.5
—
—
—
0
0
38
234
1.63
2.17
1.5
1.5
—
—
—
0
0
62
427
1.46
2.17
1.2
1.2
—
—
—
0
0
72
511
1.42
2.15
5.6
3.2
1.7
1.6
mmol/l
0.68
72
499
37
227
1.64
2.15
2.5
1.5
—
—
—
0
0
40
251
1.60
2.13
1.3
1.2
—
—
—
0
0
13
55
2.37
2.12
1.5
1.3
—
—
—
0
0
74
530
1.41
2.11
3.6
3.0
7.7
7.9
kpa
0.50
68
483
22
116
1.90
2.11
2.1
1.6
—
—
—
0
0
68
481
1.43
2.08
5.9
3.3
8.2
7.6
mmol/l
0.91
68
470
130
1020
1.29
2.05
1.1
1.2
108.9
138.4
iu/ml
0.44
50
362
7
20
3.51
2.05
1.4
1.5
—
—
—
0
0
34
208
1.64
2.01
1.9
1.4
6737.6
114439.2
e6/l
1.43
25
140
14
63
2.23
2.01
1.4
1.2
—
—
—
0
0
20
104
1.93
2.00
1.2
1.4
1.1
1.1
nmol/l
0.01
15
75
43
280
1.55
1.98
1.9
1.4
18580.7
72098.0
e6/l
1.31
29
165
32
195
1.65
1.93
5.4
3.1
26.4
36.9
mg/l
0.23
24
147
72
523
1.39
1.92
9.8
6.9
11.7
11.1
mmol/l
0.74
65
464
72
523
1.39
1.92
9.8
6.9
104.6
105.4
mmol/l
0.59
65
464
82
609
1.36
1.91
3.8
3.2
23.2
25.1
mmol/l
3.05
70
528
600
5456
1.13
1.90
1.7
1.7
1.5
1.3
mmol/l
2.95
537
4500
19
99
1.93
1.90
1.4
1.3
128.2
141.1
nmol/l
0.51
19
99
110
858
1.30
1.84
2.4
3.7
39.5
61.9
u/ml
1.10
104
821
65
468
1.40
1.84
1.8
1.8
43.9
43.0
nmol/l
0.10
59
442
148
1813
0.80
1.82
4.4
4.0
1.2
1.2
mmol/l
0.05
134
1586
140
1129
1.26
1.80
5.3
3.6
—
—
—
0
0
46
313
1.48
1.76
1.8
1.4
1362.8
1605.7
e6/l
0.42
34
221
94
723
1.31
1.76
8.5
6.1
1.3
1.3
mmol/l
0.18
83
635
14
67
2.10
1.76
1.5
2.1
—
—
—
0
0
31
193
1.61
1.75
1.8
1.3
1.6
1.5
nmol/l
0.19
31
169
6
18
3.34
1.74
2.0
1.1
152.1
158.9
mmol/l
—
6
13
8
30
2.67
1.72
1.4
1.6
44.4
48.0
umol/l
—
8
30
25
148
1.70
1.70
4.8
2.3
—
—
—
0
0
55
760
0.72
1.67
1.8
1.5
—
—
—
0
0
6
19
3.16
1.66
1.2
1.1
—
—
—
0
0
39
261
1.50
1.63
1.7
1.6
—
—
—
0
0
25
150
1.67
1.63
1.2
1.2
—
—
—
0
0
167
1391
1.22
1.62
4.1
3.2
—
—
—
0
0
23
135
1.71
1.62
1.9
2.1
511.9
682.6
e6/l
—
10
61
12
56
2.15
1.61
1.5
1.5
2.4
2.0
umol/l
0.87
12
49
23
138
1.67
1.51
1.0
1.1
—
—
—
0
0
18
101
1.79
1.49
1.1
1.0
—
—
—
0
0
13
65
2.01
1.48
2.8
2.2
—
—
—
0
0
9
37
2.44
1.48
1.2
1.1
—
—
—
0
0
111
896
1.25
1.47
1.2
1.3
—
—
—
0
0
24
148
1.63
1.44
1.5
1.3
—
—
—
0
0
36
245
1.48
1.42
1.1
1.2
—
—
—
0
0
16
88
1.82
1.41
1.3
1.2
—
—
—
0
0
11
53
2.08
1.38
1.3
1.3
68.6
69.3
mu/l
0.01
11
40
24
150
1.61
1.38
1.1
1.6
125.6
1754.9
u/l
—
6
52
207
1789
1.17
1.37
5.0
4.0
1.0
0.9
%
0.22
72
558
13
68
1.92
1.33
2.1
1.6
—
—
—
0
0
40
284
1.42
1.29
1.0
1.0
—
—
—
0
0
20
122
1.64
1.27
1.1
1.3
0.0
0.9
u/ml
—
10
66
36
254
1.42
1.22
2.0
2.6
—
—
—
0
0
58
445
1.31
1.19
1.1
1.2
4.1
3.9
mmol/l
0.64
58
415
19
117
1.63
1.18
1.6
1.8
—
—
—
0
0
12
64
1.88
1.18
1.4
1.2
13.3
24.7
%
1.74
12
47
21
133
1.58
1.17
2.3
2.1
345.8
134.0
ug/min
—
5
32
7
30
2.34
1.12
1.4
1.0
—
—
—
0
0
7
30
2.34
1.12
1.4
1.2
—
—
—
0
0
45
336
1.35
1.12
1.5
1.3
12.6
10.5
u/l
0.36
36
267
5
115
0.43
1.11
1.0
1.6
—
—
—
0
0
41
302
1.36
1.11
1.0
1.1
42.8
81.9
iu/ml
—
5
52
35
251
1.40
1.10
1.8
1.5
—
—
—
0
0
5
21
2.38
1.09
1.0
1.1
—
—
—
0
0
7
32
2.19
1.08
2.3
1.4
206.9
127.8
ng/l
—
7
32
7
32
2.19
1.08
17.6
14.6
4.5
5.5
mmol/l
—
7
32
48
365
1.32
1.07
1.5
1.4
—
—
—
0
0
40
531
0.75
1.03
5.9
5.0
2.9
2.7
mmol/l
0.18
30
373
13
75
1.74
1.02
2.2
2.0
—
—
—
0
0
63
501
1.26
1.02
1.2
1.3
599.6
549.7
mg/l
0.24
63
468
11
61
1.81
0.98
1.3
1.2
361.0
134.6
ug/l
—
6
30
5
23
2.18
0.98
1.2
1.8
17.1
17.2
umol/l
—
5
23
34
249
1.37
0.97
1.4
1.6
—
—
—
0
0
73
595
1.23
0.96
1.5
1.7
—
—
—
0
0
25
174
1.44
0.95
1.2
1.1
—
64.0
—
0
7
19
125
1.52
0.94
2.1
2.1
14.5
15.3
%
—
6
46
59
472
1.26
0.93
1.0
1.1
—
—
—
0
0
21
142
1.48
0.92
1.1
1.7
—
—
—
0
0
19
126
1.51
0.91
1.5
1.5
—
—
—
0
0
179
1587
1.14
0.91
5.2
4.0
0.0
0.3
%
0.70
54
428
40
306
1.31
0.89
1.2
1.2
96.5
206.6
miu/ml
1.99
13
125
30
403
0.74
0.87
2.1
1.7
—
—
—
0
0
8
44
1.82
0.86
1.3
1.2
—
—
—
0
0
29
213
1.37
0.84
1.1
1.1
—
—
—
0
0
54
434
1.25
0.83
1.3
1.5
379.9
779.6
e6/l
0.56
47
348
54
434
1.25
0.83
1.2
1.4
5.4
32.4
e6/l
1.20
46
332
35
266
1.32
0.82
1.7
1.5
—
—
—
0
0
33
249
1.33
0.82
3.6
3.5
54.7
57.1
%
0.22
26
153
6
32
1.88
0.81
1.5
3.4
35.0
41.7
umol/l
—
6
25
13
81
1.61
0.81
1.2
1.1
—
—
—
0
0
19
130
1.47
0.80
1.3
1.1
—
—
—
0
0
20
139
1.44
0.79
1.5
1.4
1618.4
1853.5
ml
—
5
26
24
173
1.39
0.78
2.1
2.1
1.3
1.0
e9/l
0.41
12
100
8
48
1.67
0.78
1.7
1.5
—
—
—
0
0
189
1703
1.12
0.77
5.3
4.0
0.1
0.1
%
0.01
60
520
51
626
0.81
0.76
5.3
4.6
7.4
7.4
ph
0.43
38
525
181
1629
1.12
0.75
4.6
3.8
0.5
0.6
%
0.30
51
391
31
236
1.32
0.74
1.1
1.2
—
—
—
0
0
170
1529
1.12
0.72
2.7
2.2
11.6
12.7
nmol/l
0.93
150
1327
24
176
1.37
0.72
2.1
2.3
—
—
—
0
0
27
202
1.34
0.72
1.7
1.4
32.9
27.5
%
0.23
14
123
34
264
1.29
0.71
1.0
1.1
—
—
—
0
0
33
257
1.29
0.68
3.8
4.2
—
—
—
0
0
12
77
1.56
0.68
1.3
1.4
26.1
21.9
umol/l
0.16
12
72
51
419
1.22
0.68
1.9
1.8
5.1
4.5
iu/l
0.13
15
136
5
28
1.79
0.66
1.0
1.4
43.3
41.1
pmol/l
—
5
23
48
394
1.22
0.65
3.6
3.6
0.8
1.5
%
1.51
41
300
7
44
1.59
0.65
1.1
1.1
—
—
—
0
0
21
154
1.37
0.65
2.3
2.1
1.9
2.0
ug/l
0.11
16
129
33
260
1.27
0.64
1.6
7.0
7.2
7.5
mmol/l
0.13
23
220
41
333
1.24
0.62
2.7
2.6
—
—
—
0
0
20
147
1.36
0.61
1.2
1.0
4.7
2.0
u/ml
—
8
43
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
8
50
1.60
0.61
4.9
8.7
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
0.5
—
0
14
0
22
0.00
0.59
0.0
1.1
—
—
—
0
0
8
53
1.51
0.58
1.6
2.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.3
—
—
—
0
0
67
576
1.17
0.58
1.1
1.1
—
—
—
0
0
26
202
1.29
0.57
1.4
1.5
—
—
—
0
0
8
55
1.46
0.56
1.3
1.0
—
—
—
0
0
25
194
1.29
0.56
1.1
1.1
4.2
1.2
u/ml
0.36
13
77
33
406
0.81
0.55
4.0
3.5
59.1
58.2
%
0.19
33
406
29
231
1.26
0.54
1.3
1.3
278.5
275.7
mosm/kgh2o
0.20
19
171
27
214
1.26
0.52
1.4
1.6
—
—
—
0
0
32
391
0.82
0.51
3.7
3.3
4.3
4.3
e9/l
0.01
32
391
11
77
1.43
0.45
1.7
2.9
120.1
96.4
umol/l
—
5
49
19
147
1.29
0.45
1.1
1.2
2.1
2.1
mmol/l
0.01
19
137
43
367
1.17
0.44
3.8
3.4
—
—
—
0
0
46
395
1.17
0.44
1.2
1.4
—
—
—
0
0
25
202
1.24
0.43
1.1
1.2
—
—
—
0
0
11
78
1.41
0.43
1.0
1.4
—
—
—
0
0
57
499
1.15
0.43
2.6
2.3
—
—
—
0
0
8
56
1.43
0.42
2.0
1.5
—
—
—
0
0
25
203
1.23
0.42
1.2
1.4
—
—
—
0
0
21
167
1.26
0.41
1.0
1.1
0.9
1.6
u/ml
0.37
11
65
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.1
—
—
—
0
0
8
60
1.33
0.40
1.5
2.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
—
—
0
0
5
35
1.43
0.39
1.2
1.1
—
—
—
0
0
0
19
0.00
0.39
0.0
1.9
—
1.1
—
0
13
0
19
0.00
0.39
0.0
1.1
—
—
—
0
0
5
37
1.35
0.37
5.6
8.0
—
—
—
0
0
23
192
1.20
0.32
3.0
2.2
841.9
636.0
ml
1.26
16
118
26
220
1.18
0.31
1.2
1.3
—
—
—
0
0
15
119
1.26
0.31
1.1
1.1
1.9
3.1
u/ml
—
9
53
13
101
1.29
0.31
1.0
1.1
—
—
—
0
0
14
110
1.27
0.31
1.4
2.5
9.1
9.3
mmol/l
—
8
90
48
427
1.13
0.31
1.4
1.5
—
—
—
0
0
7
52
1.35
0.31
1.7
2.2
7.7
7.8
%
—
7
45
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
7
54
1.30
0.30
1.1
1.1
—
—
—
0
0
10
75
1.33
0.30
2.2
2.5
—
—
—
0
0
24
203
1.18
0.30
1.2
1.2
—
—
—
0
0
8
62
1.29
0.28
1.0
1.1
—
—
—
0
0
8
67
1.19
0.26
1.0
1.3
—
—
—
0
0
9
72
1.25
0.25
1.3
1.3
—
—
—
0
0
14
114
1.23
0.25
1.7
2.6
—
—
—
0
0
13
105
1.24
0.24
1.4
1.0
—
—
—
0
0
6
84
0.71
0.24
1.5
1.1
—
—
—
0
0
12
147
0.82
0.23
1.0
1.0
—
—
—
0
0
20
171
1.17
0.23
1.1
1.0
3.2
3.6
u/ml
0.05
13
73
30
267
1.13
0.21
1.3
1.3
—
—
—
0
0
5
42
1.19
0.21
1.2
1.1
—
—
—
0
0
5
42
1.19
0.21
1.0
3.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.8
—
—
—
0
0
5
43
1.16
0.21
1.0
1.3
—
—
—
0
0
5
43
1.16
0.21
1.2
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
101.3
—
0
13
6
48
1.25
0.20
1.2
1.3
—
—
—
0
0
6
48
1.25
0.20
2.2
1.5
—
—
—
0
0
6
51
1.18
0.19
1.7
2.2
26.3
30.2
%
—
6
46
7
60
1.17
0.17
1.1
1.3
—
—
—
0
0
16
138
1.16
0.17
2.1
2.4
—
—
—
0
0
56
524
1.07
0.16
5.2
4.0
—
—
—
0
0
11
92
1.20
0.16
1.5
1.2
—
—
—
0
0
13
151
0.86
0.15
1.2
1.2
—
—
—
0
0
6
78
0.77
0.15
1.3
1.2
232.0
214.7
iu/ml
—
6
78
14
122
1.15
0.13
1.1
1.3
—
—
—
0
0
61
578
1.06
0.13
1.3
1.2
—
—
—
0
0
16
142
1.13
0.12
1.3
1.5
15.0
14.1
umol/l
0.19
16
134
14
124
1.13
0.11
1.5
1.5
—
—
—
0
0
14
124
1.13
0.11
2.5
3.0
—
—
—
0
0
44
416
1.06
0.11
1.3
1.3
—
—
—
0
0
17
187
0.91
0.10
1.1
1.1
—
—
—
0
0
5
47
1.06
0.09
1.4
2.9
—
—
—
0
0
17
186
0.91
0.09
1.1
1.1
—
—
—
0
0
14
155
0.90
0.09
4.2
4.9
28.2
49.9
u/ml
—
8
39
6
55
1.09
0.09
1.0
1.0
—
—
—
0
0
15
136
1.10
0.08
3.5
2.0
529.7
487.1
min
1.34
15
95
7
67
1.04
0.08
1.6
1.4
—
—
—
0
0
14
127
1.10
0.08
1.1
1.0
0.4
2.8
u/ml
—
7
54
53
512
1.04
0.06
3.7
2.5
16.4
16.0
%
0.29
37
259
38
366
1.04
0.05
1.4
1.3
37.3
34.5
iu/l
0.16
33
307
10
110
0.91
0.05
5.3
6.1
—
—
—
0
0
65
634
1.03
0.05
1.1
1.1
—
—
—
0
0
503
5060
0.99
0.04
4.5
3.6
—
—
—
0
0
66
673
0.98
0.03
13.5
10.6
—
—
—
0
0
15
159
0.94
0.03
1.3
1.1
—
—
—
0
0
25
258
0.97
0.02
1.3
1.1
—
12.5
—
0
10
12
127
0.94
0.01
1.6
2.3
—
—
—
0
0
14
138
1.01
0.00
1.1
1.1
0.2
4.9
nmol/l
—
7
29
14
138
1.01
0.00
2.4
1.6
—
71.6
—
0
9
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
5
56
0.89
0.00
4.6
2.4
317.4
138.2
nmol/l
—
5
49
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
5
55
0.91
0.00
1.2
1.1
1376.2
1636.5
miu/ml
—
5
55
0
6
0.00
0.00
0.0
4.7
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
10.2
—
0
5
0
5
0.00
0.00
0.0
1.2
—
3776.0
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
1.6
—
0
5
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint CD2_BENIGN_DESCENDING_COLON and mortality.

Females

Parameter HR [95% CI] p-value
CD2_BENIGN_DESCENDING_COLON 1.226 [1.09, 1.38] < 0.001
Birth year 0.995 [0.99, 1.0] 0.251

During the follow-up period (1.1.1998 — 31.12.2019), 872 out of 4109 females with CD2_BENIGN_DESCENDING_COLON died.

Males

Parameter HR [95% CI] p-value
CD2_BENIGN_DESCENDING_COLON 1.327 [1.18, 1.5] < 0.001
Birth year 0.985 [0.98, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 1413 out of 5120 males with CD2_BENIGN_DESCENDING_COLON died.

Mortality risk

Mortality risk for people of age

years, who have CD2_BENIGN_DESCENDING_COLON.

N-year risk Females Males
1 0.109% 0.179%
5 0.695% 1.384%
10 2.046% 3.572%
15 3.64% 6.784%
20 6.548% 11.258%

Relationships between endpoints

Index endpoint: CD2_BENIGN_DESCENDING_COLON – Benign neoplasm: Descending colon

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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