Other diseases of gallbladder

K11_GALLBLAOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K82
  • Hospital discharge: ICD-9 575[3-9]
  • Hospital discharge: ICD-8 57600|57602|57604
  • Cause of death: ICD-10 K82
  • Cause of death: ICD-9 575[3-9]
  • Cause of death: ICD-8 57600|57602|57604

2 out of 7 registries used, show all original rules.

1815

4. Check minimum number of events

None

1815

5. Include endpoints

None

1815

6. Filter based on genotype QC (FinnGen only)

1753

Control definitions (FinnGen only)

Control exclude
K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K80-K87
Name in latin
Alii morbi vesicae biliaris

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 14816 9612 5039
Only index persons 11458 7755 3703
Unadjusted period prevalence (%)
Whole population 0.23 0.28 0.14
Only index persons 0.24 0.29 0.14
Median age at first event (years)
Whole population 53.44 50.94 58.14
Only index persons 50.54 48.38 55.05

-FinnGen-

Key figures

All Female Male
Number of individuals 1753 1099 654
Unadjusted period prevalence (%) 0.36 0.39 0.30
Median age at first event (years) 50.37 46.06 57.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1814
Matched controls
18140
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K82.8
ICD-10 Finland
Other specified diseases of gallbladder
+∞
307.7
369
*
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
201.5
307.7
419
27
57600
ICD-8 Finland
Other diseases of gallbladder and biliary, Cholesterosis vesicae felleae
+∞
307.7
391
*
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
946.0
307.7
622
10
K82.9
ICD-10 Finland
Disease of gallbladder, unspecified
+∞
296.2
276
*
JKA20
NOMESCO Finland
Cholecystectomy
45.8
267.9
159
38
K82.4
ICD-10 Finland
Cholesterolosis of gallbladder
+∞
234.6
220
*
K82.2
ICD-10 Finland
Perforation of gallbladder
+∞
205.2
193
*
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
27.0
172.2
119
47
5756A
ICD-9 Finland
Other disorders of gallbladder, Cholesterolosis of gallbladder
+∞
171.6
162
*
UJK02
NOMESCO Finland
ERCP
54.4
163.2
93
18
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.4
140.1
869
3879
K80.0
ICD-10 Finland
Calculus of gallbladder with acute cholecystitis
372.5
139.8
139
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.9
112.5
279
653
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.6
109.5
463
1594
6662
FHL
Cholecystectomy
234.0
107.9
110
5
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
56.7
97.2
55
10
6663
FHL
Cholecystectomy and cholangiography
498.5
96.3
95
*
K80.5
ICD-10 Finland
Calculus of bile duct without cholangitis or cholecystitis
198.1
91.2
94
5
JL5SB
NOMESCO Finland
Endoscopic retrograd cholangiopancreaticography
47.7
87.0
51
11
K82.0
ICD-10 Finland
Obstruction of gallbladder
+∞
80.8
77
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.5
74.6
685
3503
K80.1
ICD-10 Finland
Calculus of gallbladder with other cholecystitis
704.4
69.5
68
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.2
69.3
325
1166
K80.8
ICD-10 Finland
Other cholelithiasis
30.7
68.3
45
15
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
8.7
65.1
84
101
K83.0
ICD-10 Finland
Cholangitis
+∞
65.0
62
*
A02BC05
ATC
esomeprazole; systemic
2.3
61.1
847
5077
57409
ICD-8 Finland
Cholelithiasis, Unspecified
+∞
59.7
57
*
K81.0
ICD-10 Finland
Acute cholecystitis
107.0
57.2
62
6
5759X
ICD-9 Finland
Other disorders of gallbladder, Unspecified disorder of gallbladder
+∞
56.6
54
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
54.9
239
815
K85
ICD-10 Finland
Acute pancreatitis
268.0
51.4
52
*
K85.9
ICD-10 Finland
Acute pancreatitis, unspecified
+∞
48.1
46
*
JKE02
NOMESCO Finland
Transduodenal endoscopic incision of common bile duct orifice
78.1
47.2
53
7
JN3AD
NOMESCO Finland
Abdominal CT examination
2.9
46.4
250
958
A02BC02
ATC
pantoprazole; systemic
2.1
44.9
1301
9862
K81.9
ICD-10 Finland
Cholecystitis, unspecified
+∞
43.9
42
*
N02AX02
ATC
tramadol; systemic, rectal
2.0
43.8
851
5582
K83.1
ICD-10 Finland
Obstruction of bile duct
153.7
43.0
45
*
5758X
ICD-9 Finland
Other disorders of gallbladder, Other specified disorders of gallbladder
+∞
42.9
41
*
5742A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder without mention of cholecystitis[CHOLECYSTOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
+∞
41.8
40
*
UJF32
NOMESCO Finland
Coloscopy
2.1
41.8
555
3166
A06AC01
ATC
ispaghula (psylla seeds); oral
2.1
41.1
572
3318
A09AA02
ATC
multienzymes (lipase, protease etc.); oral
9.5
40.2
48
52
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
14.9
39.1
35
24
A05AA02
ATC
ursodeoxycholic acid; oral
8.2
38.9
52
65
K30
ICD-10 Finland
Functional dyspepsia
2.6
38.7
246
1022
JL5CG
NOMESCO Finland
Extensive MRI examinaiton of bile and pancreas ducts with high intesity magnet
52.4
38.7
46
9
WX408
NOMESCO Finland
General anesthesy, balanced
2.1
38.5
500
2815
JKE12
NOMESCO Finland
Endoscopic extraction of calculus from bile duct
+∞
37.6
36
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.0
37.1
583
3506
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.3
36.6
347
1725
WX402
NOMESCO Finland
General anaesthesia
2.1
34.0
389
2077
A02BC03
ATC
lansoprazole; oral
1.9
32.5
589
3683
K80.3
ICD-10 Finland
Calculus of bile duct with cholangitis
+∞
32.4
31
*
A02BA02
ATC
ranitidine; systemic
2.0
32.0
416
2323
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.2
30.7
126
411
JKE18
NOMESCO Finland
Endoscopic internal drainage of bile duct
38.8
30.3
38
10
K82.3
ICD-10 Finland
Fistula of gallbladder
+∞
30.3
29
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
30.2
682
4543
A02BC01
ATC
omeprazole; systemic
1.9
30.0
540
3353
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
29.3
871
6266
TJK01
NOMESCO Finland
Laparoscopic cholangiography
+∞
29.2
28
*
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
9.6
28.9
34
36
J01MA02
ATC
ciprofloxacin; systemic
1.8
28.2
737
5095
D37.6
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Liver, gallbladder and bile ducts
6.2
28.1
48
79
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
+∞
27.1
26
*
N03AX16
ATC
[U] pregabalin
1.9
27.0
449
2706
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
26.6
385
2216
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.9
26.3
391
2271
ZXE00
NOMESCO Finland
One hour or less
1.7
25.5
706
4923
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
25.0
412
2468
P01AB01
ATC
metronidazole; oral, rectal
1.7
24.4
709
4995
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.1
23.8
41
68
K80.4
ICD-10 Finland
Calculus of bile duct with cholecystitis
126.7
23.6
25
*
JAH01
NOMESCO Finland
Laparoscopy
3.3
22.9
86
266
A03FA02
ATC
cisapride; oral, rectal
2.4
22.8
170
755
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
21.8
198
957
D01
ICPC
Abdominal pain/cramps general
2.1
21.1
208
1038
UJF30
NOMESCO Finland
Ileoscopy through colon
2.2
21.0
200
983
D02
ICPC
Abdominal pain epigastric
2.7
20.9
117
453
K85.8
ICD-10 Finland
Other acute pancreatitis
+∞
20.9
20
*
UJK12
NOMESCO Finland
Peroral cholangioscopy
+∞
20.9
20
*
K80
ICD-10 Finland
Cholelithiasis
19.7
20.8
31
16
J01DB01
ATC
cefalexin; oral
1.7
20.7
1419
12210
K83.9
ICD-10 Finland
Disease of biliary tract, unspecified
212.3
20.6
21
*
R10.0
ICD-10 Finland
Acute abdomen
3.6
20.5
68
194
J01MA12
ATC
levofloxacin; systemic
1.8
20.4
333
1977
K82.1
ICD-10 Finland
Hydrops of gallbladder
+∞
19.8
19
*
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
19.7
191
945
ZXD10
NOMESCO Finland
Scheduled procedure
1.6
19.7
686
4987
K85.0
ICD-10 Finland
Idiopathic acute pancreatitis
202.1
19.6
20
*
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
4.2
19.4
52
127
M79.6
ICD-10 Finland
Pain in limb
1.6
19.4
724
5344
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.6
19.4
117
471
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.0
19.2
88
306
D06
ICPC
Abdominal pain localized other
2.2
18.9
162
763
N02BE01
ATC
paracetamol; systemic, rectal
1.9
18.9
1575
14081
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
7.4
18.7
27
37
M54.5
ICD-10 Finland
Low back pain
1.6
18.5
602
4293
R03AC02
ATC
salbutamol; inhalant
1.5
17.7
933
7394
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
17.6
341
2122
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.9
17.6
85
305
TJK00
NOMESCO Finland
Intraoperative cholangiography
181.7
17.5
18
*
K86.2
ICD-10 Finland
Cyst of pancreas
181.7
17.5
18
*
R17
ICD-10 Finland
Hyperbilirubinaemia, with or without jaundice, not elsewhere classified
5.6
17.5
33
60
WX002
NOMESCO Finland
Sedation and analgesia
1.7
17.4
362
2297
A03CA02
ATC
clidinium and psycholeptics; oral
2.4
17.3
129
572
H02AB06
ATC
prednisolone; systemic
1.5
17.1
828
6425
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.8
17.0
296
1784
57408
ICD-8 Finland
Cholelithiasis, Alia definita
+∞
16.7
16
*
D13.5
ICD-10 Finland
Benign neoplasm: Extrahepatic bile ducts
+∞
16.7
16
*
57401
ICD-8 Finland
Cholelithiasis, Cum cholecystitide chronica
+∞
16.7
16
*
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
16.6
195
1035
JKE22
NOMESCO Finland
Endoscopic extraction of foreign body from bile duct
171.5
16.5
17
*
C10AC01
ATC
colestyramine; oral
3.7
16.5
53
148
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
4.2
16.4
44
108
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.6
16.1
410
2736
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
16.0
1112
9260
A02BC04
ATC
rabeprazole; oral
2.1
15.9
162
817
M54.4
ICD-10 Finland
Lumbago with sciatica
1.7
15.8
301
1858
M03BX02
ATC
tizanidine; oral
1.5
15.7
1000
8163
ZXD05
NOMESCO Finland
Urgent procedure
1.6
15.7
508
3592
R53
ICD-10 Finland
Malaise and fatigue
1.6
15.6
429
2916
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.1
15.5
65
215
K83.8
ICD-10 Finland
Other specified diseases of biliary tract
161.3
15.5
16
*
K29.7
ICD-10 Finland
Gastritis, unspecified
2.9
15.3
73
260
Z3226
NOMESCO Finland
Physiotherapist
1.7
15.2
333
2135
Z2221
NOMESCO Finland
Medical doctor
1.6
15.2
476
3335
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
4.2
15.1
40
97
J45
ICD-10 Finland
Asthma
2.0
15.1
185
995
M25.5
ICD-10 Finland
Pain in joint
1.6
15.1
518
3704
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.9
15.1
211
1187
Z3231
NOMESCO Finland
Registered nurse
1.6
15.0
474
3326
R52.9
ICD-10 Finland
Pain, unspecified
2.0
15.0
171
898
A02BA04
ATC
nizatidine; systemic
2.1
14.9
153
773
J02AC01
ATC
fluconazole; systemic
1.5
14.9
647
4868
R06.0
ICD-10 Finland
Dyspnoea
1.6
14.8
478
3370
5754A
ICD-9 Finland
Other disorders of gallbladder, Perforation of gallbladder
+∞
14.6
14
*
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.7
14.5
78
296
R96
ICPC
Asthma
1.9
14.4
178
960
C03CA01
ATC
furosemide; systemic
1.5
14.4
594
4415
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
14.2
466
3293
N03AX12
ATC
[U] gabapentin; oral
1.7
14.2
288
1808
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
14.2
225
1316
H02AB04
ATC
methylprednisolone; systemic
1.8
14.1
254
1542
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
14.0
72
267
K76.0
ICD-10 Finland
Fatty (change of) liver, not elsewhere classified
3.5
14.0
48
140
R4110
NOMESCO Finland
Physiotherapy
1.5
13.9
483
3456
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
13.6
1137
9667
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
13.6
691
5341
JKE32
NOMESCO Finland
Endoscopic dilatation of bile duct
75.7
13.6
15
*
K86.1
ICD-10 Finland
Other chronic pancreatitis
75.7
13.6
15
*
R01AD09
ATC
mometasone; nasal
1.5
13.6
710
5518
K76.9
ICD-10 Finland
Liver disease, unspecified
4.6
13.6
32
71
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
13.3
644
4926
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.3
13.3
97
427
WX704
NOMESCO Finland
Intubation
2.1
13.3
132
659
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
13.1
321
2113
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
13.1
333
2212
A03DA02
ATC
pitofenone and analgesics; systemic
3.4
13.1
46
137
M01AH02
ATC
rofecoxib; oral
1.7
13.0
236
1433
J01FA09
ATC
clarithromycin; systemic
1.5
13.0
499
3638
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
12.8
627
4799
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
12.7
342
2301
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
12.7
234
1428
J01DA01
ATC
[U] cefalexin
1.4
12.6
1044
8798
R12
ICD-10 Finland
Heartburn
2.0
12.6
134
686
R11
ICD-10 Finland
Nausea and vomiting
2.0
12.5
147
779
K82
ICD-10 Finland
Other diseases of gallbladder
+∞
12.5
12
*
K81.1
ICD-10 Finland
Chronic cholecystitis
+∞
12.5
12
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
12.4
275
1762
M01AH05
ATC
etoricoxib; oral
1.4
12.3
987
8253
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.8
12.2
59
212
C23
ICD-10 Finland
Malignant neoplasm of gallbladder
37.8
12.2
15
*
M48.0
ICD-10 Finland
Spinal stenosis
1.7
12.2
235
1451
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
12.1
284
1845
R07.3
ICD-10 Finland
Other chest pain
1.8
12.1
181
1039
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.7
12.0
232
1432
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
12.0
189
1100
D98
ICPC
Cholecystitis/cholelithiasis
21.4
12.0
17
8
R03DC03
ATC
montelukast; oral
1.7
12.0
262
1673
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
11.8
268
1727
L04AX01
ATC
azathioprine; systemic
2.5
11.8
73
298
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
11.8
125
639
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.6
11.7
67
263
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
11.7
244
1537
D07AB02
ATC
hydrocortisone butyrate; topical
1.5
11.6
477
3511
JK3BT
NOMESCO Finland
Catherisation of bile duct with X-ray guidance
65.4
11.6
13
*
N06AX21
ATC
duloxetine; oral
1.8
11.6
189
1112
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
11.6
352
2431
C07AB07
ATC
bisoprolol; oral
1.4
11.6
872
7183
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
3.2
11.5
44
138
R51.80
ICD-10 Finland
Headache
1.7
11.5
242
1528
J01FA10
ATC
azithromycin; systemic
1.4
11.5
882
7282
5741A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder with other cholecystitis[CHOLECYSTOLITHIASIS CUM CHOLECYSTITIDE CHR,SINE OBS]
+∞
11.5
11
*
57500
ICD-8 Finland
Cholecystitis and cholangitis, without mention of calculus, Cholecystitis acuta
+∞
11.5
11
*
5740A
ICD-9 Finland
Cholelithiasis, Calculus of gallbladder with acute cholecystitis[CHOLECYSTOLITHIASIS CUM CHOLECYSTITIDE AC,SINE OBST]
+∞
11.5
11
*
K85.1
ICD-10 Finland
Biliary acute pancreatitis
+∞
11.5
11
*
U07
ICPC
Urine symptom/complaint other
1.9
11.4
141
760
N05BA01
ATC
diazepam; systemic, rectal
1.7
11.4
229
1429
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
11.3
325
2217
UJD02
NOMESCO Finland
Gastroscopy
2.2
11.3
92
425
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.8
11.3
176
1023
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
11.2
246
1571
R01AD08
ATC
fluticasone; nasal
1.5
11.1
437
3186
M01AH01
ATC
celecoxib; oral
1.6
11.1
312
2116
ZXA05
NOMESCO Finland
Left side
1.5
11.1
441
3223
M02AA07
ATC
piroxicam; topical
1.4
11.0
636
4984
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.7
11.0
57
213
L17
ICPC
Foot/toe symptom/complaint
1.5
10.9
474
3521
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
4.9
10.7
23
47
R02
ICPC
Shortness of breath/dyspnoea
1.7
10.7
221
1388
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.5
10.7
395
2840
G44.2
ICD-10 Finland
Tension-type headache
1.7
10.7
215
1342
1413
FHL
Laparoscopy and other therapeutic procedure
3.1
10.7
44
145
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.1
10.7
99
482
AA1AD
NOMESCO Finland
CT of head and brain
1.5
10.7
483
3617
R13
ICD-10 Finland
Dysphagia
1.9
10.6
126
670
J01EA01
ATC
trimethoprim; systemic
1.5
10.6
472
3521
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.1
10.6
103
511
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
3.7
10.5
33
91
A02BA03
ATC
famotidine; systemic
2.3
10.5
75
328
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
10.4
364
2585
5770A
ICD-9 Finland
Diseases of pancreas, Acute pancreatitis[PANCREATITIS ACUTA NONALCOHOLICA NONHAEMORRHAGICA]
+∞
10.4
10
*
57609
ICD-8 Finland
Other diseases of gallbladder and biliary, Alii definiti sive NUD
+∞
10.4
10
*
B01AB05
ATC
enoxaparin; parenteral
1.4
10.4
533
4080
G47.3
ICD-10 Finland
Sleep apnoea
1.5
10.4
325
2255
A07EA06
ATC
budesonide; oral, local oral
2.5
10.3
62
250
A06AD11
ATC
lactulose; oral
1.6
10.3
279
1875
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.8
10.2
145
819
M03BC51
ATC
orphenadrine, combinations; systemic
1.5
10.1
422
3104
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
10.1
101
505
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.5
10.1
428
3158
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
5.3
10.1
20
38
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
10.1
278
1874
R60.0
ICD-10 Finland
Localized oedema
1.7
10.1
212
1338
C01DA14
ATC
isosorbide mononitrate; oral
1.5
10.0
303
2086
A46
ICD-10 Finland
Erysipelas
1.6
10.0
241
1574
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
10.0
132
728
L04AA06
ATC
mycophenolic acid; systemic
3.7
10.0
31
85
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.4
9.8
64
268
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.6
9.8
56
220
J01FA06
ATC
roxithromycin; oral
1.4
9.8
661
5295
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
2.2
9.8
82
383
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.8
799
6604
JAH00
NOMESCO Finland
Laparotomy
2.7
9.8
53
203
R01AD58
ATC
fluticasone, combinations; nasal
1.5
9.8
333
2350
A03CA05
ATC
glycopyrronium bromide and psycholeptics; systemic
3.8
9.8
29
77
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.7
9.7
173
1043
M01AX17
ATC
nimesulide; oral
1.5
9.7
411
3029
TPH07
NOMESCO Finland
Cathetrisation of artery
1.7
9.7
185
1137
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
2.5
9.7
60
246
J01MA01
ATC
ofloxacin; systemic
1.8
9.7
146
840
Y0599
ICD-8 Finland
Investigation of digestive system
3.2
9.6
38
122
XF600
NOMESCO Finland
Bloodpressure measurement
2.0
9.6
107
557
R21
ICPC
Throat symptom/complaint
1.6
9.6
271
1836
R05
ICD-10 Finland
Cough
1.5
9.6
338
2402
H04.10
ICD-10 Finland
Dry eye syndrome
1.7
9.5
187
1159
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
9.5
378
2755
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
9.4
166
998
M54.3
ICD-10 Finland
Sciatica
2.0
9.4
103
533
8140/3-C23.9
ICD-O-3
Adenocarcinoma, NOS, of gallbladder
100.6
9.4
10
*
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
100.6
9.4
10
*
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
9.4
93
464
K83.4
ICD-10 Finland
Spasm of sphincter of Oddi
+∞
9.4
9
*
57709
ICD-8 Finland
Diseases of pancreas, Pancreatitis NUD
+∞
9.4
9
*
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.4
9.3
63
269
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
9.3
188
1175
A01
ICPC
Pain general/multiple sites
1.8
9.3
155
919
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.1
9.2
84
406
R03BA02
ATC
budesonide; inhalant
1.5
9.2
290
2012
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.4
9.1
399
2955
127
Kela drug reimbursment
Transplant complication
3.9
9.1
26
67
S29
ICPC
Skin symptom/complaint other
1.5
9.1
305
2142
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.3
9.1
64
278
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
9.1
137
788
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
9.1
396
2933
R06AE07
ATC
cetirizine; oral
1.4
9.1
679
5517
I20.09
ICD-10 Finland
Unstable angina
1.9
9.1
106
562
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.4
9.0
753
6220
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
9.0
139
806
XKD03
NOMESCO Finland
Urethral pressure profilometry
2.6
9.0
49
189
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.7
8.9
174
1076
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.8
224
1479
KH1AD
NOMESCO Finland
CT of urinary organs
2.5
8.8
52
208
C08CA05
ATC
nifedipine; systemic
1.9
8.8
111
603
J01AA02
ATC
doxycycline; systemic
1.4
8.8
1319
11911
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
8.8
337
2433
ZXA10
NOMESCO Finland
Bilateral
1.5
8.8
316
2253
JFB00
NOMESCO Finland
Partial resection of small intestine
3.3
8.8
32
98
R42
ICD-10 Finland
Dizziness and giddiness
1.4
8.7
384
2845
UKC02
NOMESCO Finland
Cystoscopy
1.5
8.7
260
1781
J01CA04
ATC
amoxicillin; systemic
1.4
8.7
1325
11981
N02BF01
ATC
gabapentin; oral
1.8
8.7
134
776
J45.1
ICD-10 Finland
Nonallergic asthma
1.8
8.7
120
672
JJA21
NOMESCO Finland
Laparoscopic biopsy of liver
50.2
8.7
10
*
S06.0
ICD-10 Finland
Concussion
1.7
8.7
166
1022
X58
ICD-10 Finland
Exposure to other specified factors
1.6
8.7
205
1332
L03
ICPC
Low back symptom/complaint
1.4
8.7
426
3222
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
8.6
219
1446
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
8.6
1095
9613
R03BA05
ATC
fluticasone; inhalant
1.5
8.6
282
1970
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
8.6
116
644
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
8.6
162
992
K76.80
ICD-10 Finland
Hepatic cyst
4.4
8.6
21
48
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
8.6
144
854
Z01.8
ICD-10 Finland
Other specified special examinations
1.5
8.6
355
2600
ZXD20
NOMESCO Finland
Day surgery
1.6
8.6
206
1343
SPAT1263
SPAT
Sampling
1.4
8.5
654
5321
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
8.5
618
4986
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
8.5
411
3100
R03AC03
ATC
terbutaline; inhalant
1.6
8.5
221
1470
N02AA05
ATC
oxycodone; systemic
1.5
8.4
304
2167
JKB00
NOMESCO Finland
Incision of bile duct
90.5
8.4
9
*
E0000UV, ,
ATC
1.4
8.4
648
5274
57608
ICD-8 Finland
Other diseases of gallbladder and biliary, Dyskinesia viarum biliferarum
+∞
8.3
8
*
K85.2
ICD-10 Finland
Alcohol-induced acute pancreatitis
+∞
8.3
8
*
57708
ICD-8 Finland
Diseases of pancreas, Pancreatitis acuta alia
+∞
8.3
8
*
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.8
8.3
124
711
K92.1
ICD-10 Finland
Melaena
2.0
8.3
94
494
XJD02
NOMESCO Finland
Peroral endoscopic ultrasonography
7.1
8.3
19
27
M01AB05
ATC
diclofenac; systemic, rectal
1.3
8.2
1056
9254
R31
ICD-10 Finland
Unspecified haematuria
1.7
8.2
163
1012
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
1.6
8.2
170
1070
A02BX02
ATC
sucralfate; oral
2.1
8.1
72
345
K86.9
ICD-10 Finland
Disease of pancreas, unspecified
33.5
8.1
10
*
JJ1CE
NOMESCO Finland
Liver, bile duct and pancreas endoscopic ultrasound examination
11.7
8.1
14
12
WVA20
NOMESCO Finland
Medicine administration
2.6
8.0
43
165
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
3.0
7.9
34
115
J20
ICD-10 Finland
Acute bronchitis
1.7
7.9
160
999
J46
ICD-10 Finland
Status asthmaticus
2.4
7.8
52
221
J01DA06
ATC
[U] cefuroxime
1.5
7.8
224
1521
XKC03
NOMESCO Finland
Water cystometry
2.3
7.8
58
259
S18
ICPC
Laceration/cut
1.3
7.8
724
6041
H02AB07
ATC
prednisone; oral
1.5
7.7
229
1565
L05
ICPC
Flank/axilla symptom/complaint
1.9
7.7
101
556
JK3SB
NOMESCO Finland
Endoscopic retrorade cholangiography
45.2
7.7
9
*
R03BA01
ATC
beclometasone; inhalant
1.5
7.7
224
1526
D11
ICPC
Diarrhoea
1.6
7.6
161
1016
M79.1
ICD-10 Finland
Myalgia
1.5
7.6
216
1462
K11.2
ICD-10 Finland
Sialoadenitis
2.3
7.6
53
230
K66.0
ICD-10 Finland
Peritoneal adhesions
8.1
7.6
16
20
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
2.0
7.6
85
445
R03AK07
ATC
formoterol and budesonide; inhalant
1.5
7.6
305
2219
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.4
7.6
423
3262
AN1
HP
Coronary angiography
1.6
7.5
186
1222
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
7.5
467
3665
J01DA09
ATC
[U] cefadroxil
1.4
7.5
404
3097
D09
ICPC
Nausea
2.1
7.5
65
310
K51.5
ICD-10 Finland
Left sided colitis
2.6
7.5
42
165
R05
ICPC
Cough
1.4
7.4
368
2778
L28
ICPC
Limited function/disability (L)
1.4
7.4
311
2278
M54
ICD-10 Finland
Dorsalgia
1.6
7.4
179
1168
N06AA09
ATC
amitriptyline; systemic
1.6
7.4
162
1033
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
2.6
7.4
41
160
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.6
7.4
175
1138
SPAT1254
SPAT
Administration of medicine
1.5
7.4
241
1683
R07.0
ICD-10 Finland
Pain in throat
1.9
7.3
92
500
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.3
277
1990
N05CF01
ATC
zopiclone; oral
1.3
7.3
540
4346
5745A
ICD-9 Finland
Cholelithiasis, Calculus of bile duct without mention of cholecystitis[CHOLEDOCHOLITHIASIS SINE CHOLECYSTITIDE,SINE OBSTR]
+∞
7.3
7
*
JL5CM
NOMESCO Finland
Bile and pancreas ducts extensive MRI examination with 3 Tesla magnet
+∞
7.3
7
*
5750A
ICD-9 Finland
Other disorders of gallbladder, Acute cholecystitis
+∞
7.3
7
*
H01
ICPC
Ear pain/earache
1.6
7.3
160
1021
L13
ICPC
Hip symptom/complaint
1.4
7.2
310
2281
C05AA08
ATC
fluocortolone; rectal, topical
1.5
7.2
215
1472
N02AC04
ATC
dextropropoxyphene; oral
2.0
7.2
72
362
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
2.5
7.2
44
180
L01BB02
ATC
mercaptopurine; oral
4.0
7.2
20
51
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
3.6
7.1
23
65
205
Kela drug reimbursment
Chronic hypertension
1.4
7.1
472
3733
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
7.1
365
2770
Z3229
NOMESCO Finland
Other healthcare associate professional
1.7
7.1
137
845
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.0
7.1
71
357
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
7.1
119
707
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
7.1
276
1995
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
7.1
270
1944
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.4
7.1
361
2739
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
2.1
7.0
62
297
K59.09
ICD-10 Finland
Constipation, unspecified
1.8
7.0
107
618
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
7.0
309
2286
A11
ICPC
Chest pain NOS
1.7
6.9
138
859
M01AB55
ATC
diclofenac, combinations; oral
1.7
6.9
120
721
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.7
6.8
115
684
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.3
6.8
25
77
N73.9
ICD-10 Finland
Female pelvic inflammatory disease, unspecified
3.8
6.8
20
53
M54.6
ICD-10 Finland
Pain in thoracic spine
1.8
6.8
106
617
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
6.8
525
4247
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.7
6.8
118
709
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
6.8
814
6996
A07AA02
ATC
nystatin; oral
1.8
6.7
99
566
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
6.7
288
2116
D25
ICPC
Abdominal distension
2.6
6.7
36
138
A03
ICPC
Fever
1.5
6.7
206
1419
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.5
6.7
196
1336
N06AX11
ATC
mirtazapine; oral
1.3
6.7
526
4264
A02BD02
ATC
lansoprazole, tetracycline and metronidazole; systemic
2.4
6.6
42
175
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
1.6
6.6
162
1061
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.7
6.6
106
622
A02BDXX, ,
ATC
2.0
6.6
66
332
SPAT1336
SPAT
Request for examination
2.0
6.6
65
326
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.6
685
5771
R01AD12
ATC
fluticasone furoate; nasal
1.4
6.5
422
3320
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.4
6.5
274
2006
SPAT1153
SPAT
Removal of sutures
1.3
6.5
495
3990
N39.3
ICD-10 Finland
Stress incontinence
1.7
6.5
127
787
K02.1
ICD-10 Finland
Caries of dentine
1.3
6.5
845
7326
SPAT1325
SPAT
Vaccination
1.3
6.4
543
4440
R74
ICPC
Upper respiratory infection acute
1.4
6.4
401
3136
WZC30
NOMESCO Finland
Teaching
1.5
6.4
230
1633
J01FF01
ATC
clindamycin; systemic
1.4
6.4
402
3146
Z94.4
ICD-10 Finland
Liver transplant status
14.4
6.4
10
7
M94.0
ICD-10 Finland
Chondrocostal junction syndrome [Tietze]
2.5
6.4
38
154
M01AE02
ATC
naproxen; oral, rectal
1.3
6.3
870
7581
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
8.2
6.3
13
16
T81.9
ICD-10 Finland
Unspecified complication of procedure
2.7
6.3
31
114
JKE25
NOMESCO Finland
Endoscopic external drainage of bile duct
18.1
6.3
9
5
JK3MB
NOMESCO Finland
Postoperative cholangiography
+∞
6.3
6
*
57501
ICD-8 Finland
Cholecystitis and cholangitis, without mention of calculus, Cholecystitis chronica
+∞
6.3
6
*
K81.8
ICD-10 Finland
Other cholecystitis
+∞
6.3
6
*
K83.2
ICD-10 Finland
Perforation of bile duct
+∞
6.3
6
*
JK1AT
NOMESCO Finland
Cathetrisation of bile cyst with radiological guidance
+∞
6.3
6
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.7
6.2
106
633
A01AB10
ATC
natamycin; local oral
2.1
6.2
53
252
A10BJ06
ATC
semaglutide; parenteral
2.0
6.2
66
341
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.6
6.1
125
784
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.0
6.1
65
335
N30
ICD-10 Finland
Cystitis
1.6
6.1
126
792
EB1SA, ,
SPAT
1.9
6.1
75
406
G04BD08
ATC
solifenacin; oral
1.7
6.1
113
691
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.5
6.1
172
1165
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.9
6.1
74
400
SFA10
NOMESCO Finland
One-surface restoration
1.3
6.0
794
6868
N30.0
ICD-10 Finland
Acute cystitis
1.4
6.0
257
1886
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
10.1
6.0
11
11
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
2.7
6.0
30
111
R74.0
ICD-10 Finland
Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
2.7
6.0
30
111
K29.1
ICD-10 Finland
Other acute gastritis
3.2
6.0
23
73
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
6.0
639
5380
346
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
1.9
6.0
74
401
D07CA01
ATC
hydrocortisone and antibiotics; topical
1.5
6.0
196
1367

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
395
1324
3.54
96.34
3.7
2.2
8.16
7.14
umol/l
0.41
356
1143
798
4078
2.71
90.89
3.7
2.1
61.04
56.33
u/l
0.59
751
3715
1170
7302
2.70
87.34
7.9
5.6
11.83
11.06
umol/l
1.39
1130
6899
333
1167
3.27
74.22
3.1
1.7
43.60
32.55
u/l
0.42
295
990
635
3581
2.19
51.15
5.7
3.5
88.40
89.32
%
0.37
620
3481
1436
11148
2.38
49.31
10.4
6.9
84.62
76.49
u/l
5.00
1383
10390
706
4243
2.09
47.39
4.1
2.9
35.68
31.97
u/l
0.87
680
4022
350
1732
2.26
37.38
1.3
1.3
—
—
—
0
0
961
6820
1.87
36.68
18.7
16.1
1.25
1.29
inr
0.81
273
1883
308
1493
2.28
34.34
2.4
2.1
161.42
127.37
ug/g
0.75
244
1169
369
1932
2.14
33.95
1.3
1.2
—
—
—
0
0
273
1264
2.37
33.84
2.7
1.8
0.22
0.21
g/l
0.41
258
1161
891
6397
1.77
30.68
6.2
4.3
35.03
35.35
g/l
0.96
830
5906
106
312
3.55
30.42
1.4
1.3
298.19
311.60
ug/g
0.23
66
175
136
467
3.07
30.41
3.7
3.0
92.20
2873.84
u/ml
0.71
113
398
66
143
4.75
28.62
1.6
1.5
0.71
0.82
g/l
0.41
54
118
976
7281
1.74
28.60
6.7
5.7
0.21
0.19
e9/l
1.79
851
6305
603
3930
1.80
28.34
5.4
4.0
—
—
—
0
0
1097
8473
1.75
28.22
6.2
4.3
6.84
6.69
mmol/l
1.42
1041
7912
948
7037
1.73
28.08
6.5
5.6
0.04
0.04
e9/l
0.66
812
6004
946
7024
1.72
27.95
6.5
5.6
0.60
0.58
e9/l
1.06
807
5987
963
7205
1.72
27.49
6.7
5.6
2.00
1.87
e9/l
0.67
841
6293
1068
8236
1.72
27.14
9.4
8.7
4.44
4.09
e9/l
2.92
938
7144
875
6404
1.71
26.87
6.9
5.7
0.69
0.68
%
0.09
818
5927
895
6616
1.70
26.27
7.2
6.0
8.50
8.73
%
1.56
838
6137
892
6590
1.70
26.22
6.9
5.7
2.88
2.83
%
0.30
833
6111
910
6770
1.69
25.97
7.0
5.9
27.80
27.30
%
0.67
850
6299
642
4360
1.73
25.58
4.0
3.1
46.76
84.79
e6/l
1.07
507
3348
1203
9672
1.72
25.41
6.1
4.7
109.68
3211.68
e6/l
3.15
25
136
982
7480
1.68
25.41
8.2
6.3
1.21
1.22
mmol/l
0.52
852
6308
725
5100
1.70
25.34
4.7
3.6
89.74
113.02
e6/l
0.48
533
3606
1107
8721
1.69
25.03
4.5
2.8
58.68
44.39
u/l
4.18
1034
8002
338
1898
1.96
24.97
2.6
2.5
21.53
22.03
%
0.25
292
1610
599
4012
1.74
24.95
4.0
3.1
0.46
0.49
e6/l
0.09
475
3066
894
6665
1.67
24.94
6.8
5.7
57.67
57.58
%
0.08
836
6198
587
3911
1.74
24.91
3.9
3.0
—
—
—
0
0
97
308
3.27
24.71
1.4
1.1
131.82
71.25
titre
0.54
11
24
97
310
3.25
24.45
1.4
1.1
523.33
634.55
titre
—
6
11
200
935
2.28
23.88
2.6
2.8
10.84
10.64
g/l
0.18
187
842
353
2042
1.90
23.76
2.6
2.4
2.38
2.32
g/l
1.20
337
1886
883
6621
1.65
23.63
7.5
6.0
—
—
—
0
0
281
1511
2.02
23.38
1.5
1.3
—
—
—
0
0
275
1477
2.02
22.93
3.6
4.1
10.72
22.19
ug/l
0.84
216
1213
168
741
2.40
22.91
1.8
1.8
1.55
1.58
g/l
0.04
159
669
376
2243
1.85
22.91
2.6
2.4
12.66
12.69
umol/l
0.03
355
2081
80
239
3.46
22.45
2.9
3.2
321.85
1660.90
u/ml
0.64
73
220
456
2899
1.77
22.42
3.4
2.8
524.57
533.51
mosm/kgh2o
0.39
402
2472
901
6858
1.62
22.20
7.6
5.5
1.21
1.21
mmol/l
0.88
836
6169
768
5621
1.64
22.18
4.5
3.7
103.43
46.26
ng/l
0.41
551
4023
1284
10678
1.69
22.17
5.1
4.0
13.40
13.05
mm/h
0.35
1193
9815
1216
9977
1.66
22.05
5.5
4.4
—
—
—
0
0
445
2843
1.75
21.37
4.2
3.7
278.58
354.03
ng/l
0.31
351
2311
471
3065
1.72
21.15
3.2
2.5
4.82
6.05
e6/l
1.92
430
2743
803
5993
1.61
21.08
3.2
2.7
129.39
125.89
ug/l
0.10
754
5449
397
2473
1.77
20.74
1.5
1.4
2.51
2.42
g/l
0.37
239
1438
388
2460
1.73
18.86
3.2
2.7
1.19
1.27
e6/l
0.11
211
1417
743
5553
1.57
18.71
4.4
3.5
6.28
5.84
ph
1.70
27
332
1588
14246
1.92
18.67
22.4
14.0
24.62
24.27
mg/l
0.16
1373
11173
367
2304
1.74
18.43
3.3
2.8
2.69
2.63
e6/l
0.04
191
1269
629
4549
1.59
18.11
2.8
2.3
—
—
—
0
0
897
7028
1.55
18.10
4.9
3.8
0.00
0.00
estimate
0.80
164
1233
888
6948
1.54
17.98
4.8
3.8
0.00
0.00
estimate
0.50
175
1350
217
1165
1.98
17.91
9.3
7.6
—
—
—
0
0
854
6632
1.54
17.85
3.1
2.5
—
—
—
0
0
886
6955
1.54
17.50
6.4
5.1
0.00
0.00
estimate
0.50
167
1246
655
4813
1.56
17.44
3.8
3.3
—
—
—
0
0
525
3669
1.61
17.31
6.7
6.5
—
—
—
0
0
804
6201
1.53
17.10
11.9
9.2
0.00
0.00
e9/l
0.42
644
5023
175
891
2.07
16.71
1.2
1.3
—
—
—
0
0
290
1749
1.78
16.60
1.4
1.3
362.16
530.60
titre
1.72
74
381
361
2331
1.69
16.15
3.6
3.0
0.80
0.82
mmol/l
2.61
342
2158
445
3063
1.60
15.35
2.2
1.7
1.13
1.25
mg/l
0.46
349
2342
613
4553
1.52
15.02
4.8
3.7
7.39
7.40
ph
0.94
101
813
39
94
4.22
14.88
1.3
1.1
170.00
77.69
titre
—
5
13
527
3802
1.54
14.71
2.7
2.2
3.03
3.03
mg/l
0.01
456
3180
28
52
5.45
14.49
1.1
1.0
—
—
—
0
0
487
3475
1.55
14.20
2.9
2.2
—
—
—
0
0
507
3650
1.54
14.20
2.9
2.6
3748.44
6108.31
umol/l
0.64
439
3138
296
1872
1.69
14.16
6.8
5.0
1.02
1.03
mmol/l
0.27
267
1711
1201
10292
1.49
14.06
4.5
3.9
—
—
—
0
0
412
2843
1.58
13.88
1.3
1.2
0.92
1.52
u/ml
1.40
104
722
800
6345
1.47
13.87
2.2
2.0
97.60
95.96
pmol/l
0.40
431
3074
207
1195
1.83
13.58
9.4
6.6
9.66
10.33
mmol/l
0.69
194
1137
142
725
2.04
13.43
1.4
1.2
—
—
—
0
0
333
2200
1.63
13.40
2.3
2.0
29.87
29.64
s
0.37
325
2131
243
1478
1.74
13.35
8.7
7.0
95.64
95.44
%
0.18
237
1421
1374
12167
1.53
13.24
25.1
17.0
15.25
15.06
%
0.53
1362
11922
268
1680
1.70
13.20
8.3
6.5
12.28
12.23
kpa
0.06
258
1596
268
1680
1.70
13.20
8.3
6.5
5.11
5.11
kpa
0.01
258
1595
267
1675
1.70
13.11
8.4
6.6
0.96
1.08
mmol/l
0.22
216
1321
218
1296
1.78
12.95
4.5
3.4
5.84
5.84
kpa
0.01
212
1258
305
1987
1.64
12.95
2.4
2.0
—
—
—
0
0
1618
14936
1.77
12.78
25.2
16.6
3.96
3.98
mmol/l
2.05
1586
14486
769
6120
1.45
12.76
2.6
2.2
77.60
79.04
nmol/l
0.72
694
5377
1614
14896
1.76
12.66
25.0
16.5
139.64
139.63
mmol/l
0.06
1583
14465
142
745
1.98
12.45
11.3
9.2
—
—
—
0
0
210
1249
1.77
12.45
1.6
1.5
—
—
—
0
0
215
1290
1.76
12.36
4.5
3.4
1.87
1.89
mmol/l
0.02
188
1069
98
456
2.21
11.79
3.0
3.3
—
—
—
0
0
461
3367
1.49
11.70
4.8
3.8
—
—
—
0
0
583
4472
1.45
11.47
4.1
3.7
8.64
8.68
mg/mmol
0.01
345
2716
56
204
2.80
11.34
1.2
1.2
309.46
296.94
u/ml
0.12
37
114
732
5862
1.42
11.32
2.4
2.1
—
—
—
0
0
591
4555
1.44
11.30
2.4
2.1
226.01
213.62
u/l
0.09
556
4280
1256
11058
1.44
11.26
4.4
4.0
14.99
14.90
pmol/l
0.57
1159
9940
235
1485
1.67
11.15
1.7
1.5
—
—
—
0
0
74
313
2.42
11.11
1.2
1.2
—
—
—
0
0
589
4556
1.43
10.98
3.3
3.0
1295.20
1572.48
ng/l
1.22
507
3903
59
227
2.65
10.78
1.5
1.3
—
—
—
0
0
554
4261
1.43
10.57
3.4
3.1
638.84
276.30
mg/l
0.73
339
2626
574
4452
1.42
10.43
3.3
3.0
7.40
7.07
mmol/l
0.98
476
3717
246
1600
1.62
10.39
2.0
1.7
—
—
—
0
0
333
2331
1.52
10.21
1.3
1.3
23.02
39.18
iu/ml
2.53
97
764
1454
13256
1.49
10.10
5.5
4.9
1.88
2.05
mu/l
1.10
1351
11991
53
203
2.66
9.80
1.5
1.3
124.69
113.65
u/ml
0.49
13
44
23
52
4.47
9.56
1.1
1.0
—
—
—
0
0
155
913
1.76
9.47
10.3
8.2
94.44
93.92
%
0.59
155
907
45
163
2.81
9.26
1.0
1.1
—
—
—
0
0
46
169
2.77
9.22
1.0
1.0
—
—
—
0
0
121
670
1.86
9.06
3.5
2.3
1.17
1.16
%
0.03
121
664
52
206
2.57
9.01
1.6
1.3
—
—
—
0
0
1617
15174
1.60
8.90
15.0
10.1
27.25
24.46
u/l
7.57
1571
14557
139
810
1.78
8.82
2.5
2.4
—
—
—
0
0
117
654
1.84
8.52
3.4
2.3
0.66
0.64
%
0.23
117
649
30
90
3.37
8.50
1.4
1.3
—
—
—
0
0
648
5271
1.36
8.44
3.3
3.3
2.36
2.36
mmol/l
0.03
563
4584
30
91
3.34
8.36
1.7
1.1
—
—
—
0
0
29
87
3.37
8.22
1.4
1.3
0.30
0.40
g/l
1.38
21
67
29
87
3.37
8.22
1.4
1.3
5.91
6.83
g/l
1.09
21
66
29
87
3.37
8.22
1.4
1.3
2.51
2.84
g/l
0.55
21
66
482
3755
1.39
8.18
5.6
4.2
0.01
0.00
estimate
0.06
164
1217
1578
14793
1.51
7.98
19.8
13.4
—
—
—
0
0
196
1304
1.56
7.48
1.5
1.5
—
—
—
0
0
160
1018
1.63
7.36
1.2
1.2
—
—
—
0
0
196
1320
1.54
7.08
2.5
2.4
6.78
7.02
ug/l
0.07
164
1138
114
671
1.75
7.03
4.6
3.1
25.60
25.30
mmol/l
0.40
109
651
455
3592
1.36
6.94
4.2
3.5
—
—
—
0
0
153
979
1.61
6.89
4.9
4.2
—
—
—
0
0
397
3075
1.37
6.82
5.4
4.3
1.02
1.02
kg/l
0.25
62
445
84
457
1.88
6.71
1.8
1.6
—
—
—
0
0
184
1237
1.54
6.70
2.4
2.7
66.09
66.11
g/l
0.01
168
1104
16
25
6.45
6.63
1.0
1.0
—
—
—
0
0
1292
11830
1.32
6.51
27.1
18.6
331.62
331.53
g/l
0.14
1282
11719
459
3662
1.34
6.47
1.7
1.6
21.34
21.09
nmol/l
0.13
411
3079
17
42
4.08
6.36
35.0
30.8
113.09
117.56
ug/l
0.09
11
36
227
1616
1.46
6.27
1.5
1.4
—
—
—
0
0
300
2252
1.40
6.19
1.3
1.2
9.04
13.61
u/ml
0.62
116
851
138
894
1.59
5.92
6.8
6.2
24.04
24.65
mmol/l
1.23
132
849
235
1704
1.44
5.89
2.5
2.4
1.85
1.81
%
0.20
213
1483
67
355
1.92
5.83
1.3
1.3
—
31.06
—
0
5
58
294
2.00
5.73
5.3
3.4
—
—
—
0
0
182
1264
1.49
5.70
1.9
2.0
341.30
372.61
nmol/l
1.52
164
1148
154
1033
1.54
5.68
2.5
2.5
—
—
—
0
0
16
42
3.83
5.54
2.7
1.9
—
—
—
0
0
152
1024
1.53
5.51
1.5
1.4
—
—
—
0
0
244
1806
1.41
5.45
1.8
1.7
—
—
—
0
0
187
1318
1.47
5.44
2.7
2.9
212.62
212.69
ng/l
0.00
170
1199
30
118
2.57
5.38
2.1
2.4
—
—
—
0
0
1419
13291
1.31
5.26
6.9
5.7
40.65
39.89
mmol/mol
2.34
1316
12149
15
30
5.03
5.25
1.0
1.0
—
—
—
0
0
14
26
5.42
5.22
5.1
4.8
—
—
—
0
0
93
564
1.68
5.21
2.5
1.9
7.21
1.56
ug/l
0.64
85
487
85
505
1.72
5.14
2.5
1.9
22.73
21.74
s
0.27
73
456
372
2968
1.32
5.12
1.8
1.7
1099.01
1189.39
nmol/l
1.09
286
2183
117
756
1.59
5.11
1.4
1.2
231.68
171.70
u/ml
0.61
107
682
1480
13980
1.32
4.90
5.3
4.6
6.08
5.94
mmol/l
3.62
1359
12577
28
112
2.52
4.88
1.1
1.2
—
—
—
0
0
14
29
4.86
4.81
1.1
1.2
—
—
—
0
0
40
190
2.13
4.75
1.1
1.1
—
—
—
0
0
55
294
1.90
4.72
1.4
1.6
—
—
—
0
0
122
815
1.53
4.63
1.2
1.4
—
—
—
0
0
162
1147
1.45
4.63
4.7
3.9
1.13
0.94
%
0.32
73
384
34
154
2.23
4.54
1.3
1.2
—
—
nmol/l
—
0
0
398
3257
1.28
4.48
1.8
1.7
63914801.44
23977713.48
pmol/l
0.41
327
2640
1640
15779
1.41
4.45
31.4
21.0
253.16
249.97
e9/l
1.11
1601
15316
1639
15769
1.41
4.44
31.7
21.1
39.85
39.59
%
0.96
1522
14628
1640
15783
1.41
4.41
31.3
20.9
91.16
91.38
fl
1.11
1618
15497
1640
15785
1.41
4.39
31.3
20.9
30.28
30.34
pg
0.72
1618
15498
125
850
1.51
4.38
3.0
3.2
4.41
4.45
pmol/l
0.24
114
746
1640
15786
1.41
4.38
31.4
21.0
4.44
4.43
e12/l
0.44
1593
15275
90
568
1.62
4.37
2.4
2.6
—
—
—
0
0
1640
15787
1.40
4.36
31.4
21.0
6.99
6.68
e9/l
3.42
1598
15281
1640
15790
1.40
4.33
31.6
21.1
133.48
133.52
g/l
0.04
1615
15508
73
440
1.69
4.24
6.9
5.7
1.37
1.28
mmol/l
0.28
63
384
50
273
1.86
4.07
4.2
3.2
3.64
4.37
e9/l
1.98
50
273
52
288
1.83
4.05
3.5
2.4
—
—
—
0
0
69
422
1.66
3.83
1.3
1.2
—
—
—
0
0
37
187
2.00
3.79
1.4
1.3
—
—
—
0
0
50
282
1.79
3.70
4.7
3.5
55.30
58.38
%
1.33
50
282
145
1051
1.41
3.69
4.4
3.8
0.64
0.67
%
0.08
61
337
502
4314
1.23
3.61
4.6
3.9
—
—
—
0
0
149
1090
1.40
3.60
4.9
4.0
0.10
0.11
%
0.10
60
326
143
1040
1.41
3.57
5.0
4.0
0.25
0.41
%
0.18
55
282
13
36
3.63
3.49
2.2
2.0
—
—
—
0
0
34
173
1.98
3.44
1.3
1.2
—
—
—
0
0
52
306
1.72
3.36
5.7
3.6
2.92
2.67
mmol/l
0.24
37
217
361
3016
1.25
3.35
3.3
3.0
2.48
2.46
mmol/l
1.76
288
2652
14
48
2.93
3.30
2.1
2.1
—
—
—
0
0
19
77
2.48
3.30
1.5
1.6
—
—
—
0
0
91
620
1.49
3.23
1.3
1.2
—
—
—
0
0
60
373
1.63
3.18
5.8
3.4
7.42
7.42
ph
0.01
54
335
167
1273
1.34
3.15
2.5
2.5
76.07
69.10
e9/l
1.09
122
960
118
852
1.41
3.10
4.7
3.8
7.40
7.41
ph
0.10
21
121
119
862
1.41
3.08
4.7
3.8
5.12
5.18
kpa
0.40
109
828
55
338
1.65
3.06
1.1
1.1
5.00
5.21
u/ml
—
6
35
26
126
2.08
3.03
3.1
5.1
162.38
54.04
u/ml
—
5
38
157
1194
1.34
3.02
4.2
3.7
97.86
90.34
ng/l
0.43
140
1022
50
301
1.68
3.01
1.2
1.2
167.52
240.76
miu/ml
1.04
27
128
5
5
10.02
2.98
1.2
1.0
—
—
—
0
0
32
169
1.91
2.96
3.0
3.2
—
—
—
0
0
185
1446
1.31
2.95
1.7
1.6
—
—
—
0
0
58
365
1.61
2.95
1.3
1.2
—
—
—
0
0
20
88
2.29
2.94
3.4
3.4
—
—
—
0
0
41
236
1.75
2.90
1.2
1.2
28.42
28.57
u/l
0.00
36
199
9
22
4.11
2.88
1.3
1.4
125.89
78.70
ng/l
—
9
22
15
58
2.60
2.87
1.1
1.1
1.06
1.03
ratio
—
6
18
442
3828
1.20
2.86
5.0
5.1
2.32
4.28
ug/l
1.06
391
3383
153
1169
1.34
2.86
5.5
4.0
—
—
—
0
0
97
687
1.44
2.86
1.9
1.7
1.37
1.50
g/l
0.65
82
596
42
245
1.73
2.84
4.7
2.9
—
—
—
0
0
57
363
1.59
2.78
5.8
4.6
—
—
—
0
0
85
592
1.46
2.75
5.1
3.8
—
—
—
0
0
100
718
1.42
2.75
2.9
2.5
0.28
0.27
e6/l
0.04
100
697
38
218
1.76
2.73
1.2
1.3
—
—
—
0
0
1408
13470
1.20
2.72
4.4
4.0
1.34
1.26
mmol/l
3.83
1298
12106
11
34
3.25
2.72
1.1
1.1
—
—
—
0
0
39
226
1.74
2.71
1.9
2.1
10503.93
3093.87
u/l
—
10
90
56
358
1.58
2.69
3.9
3.4
—
—
—
0
0
77
531
1.47
2.63
2.5
2.3
522.38
849.56
ug/l
0.36
72
494
23
113
2.05
2.62
1.2
1.1
—
—
—
0
0
129
975
1.35
2.61
3.2
3.2
—
—
—
0
0
101
738
1.39
2.53
4.5
3.5
—
—
—
0
0
51
327
1.58
2.45
4.5
3.6
23.10
27.14
mg/l
0.31
34
201
23
117
1.98
2.40
1.2
1.1
—
—
—
0
0
69
475
1.47
2.40
3.3
3.3
1.19
1.34
ratio
—
9
39
40
243
1.66
2.38
1.5
1.2
90.33
32.90
u/ml
—
6
25
20
97
2.07
2.37
1.5
1.5
13.79
13.31
umol/l
0.13
20
92
51
330
1.56
2.37
1.5
1.2
1.46
10.58
u/ml
—
5
61
10
33
3.04
2.35
1.5
1.6
—
—
—
0
0
70
488
1.45
2.30
3.5
3.3
36.23
164.07
mg/l
0.58
57
399
438
3861
1.18
2.29
1.8
1.6
1.46
1.33
mmol/l
2.51
383
3215
70
490
1.45
2.25
3.5
3.3
33.69
43.38
mg/l
0.54
58
402
15
66
2.28
2.24
2.6
1.9
1.10
2.88
u/field
—
10
49
23
121
1.91
2.21
1.4
1.2
—
—
—
0
0
72
510
1.43
2.19
3.1
3.3
0.30
0.28
g/l
0.07
29
195
30
174
1.74
2.14
2.9
2.3
—
—
—
0
0
10
36
2.79
2.13
1.7
1.4
—
—
—
0
0
89
658
1.37
2.12
2.3
2.0
—
—
—
0
0
13
55
2.37
2.12
1.1
1.2
—
—
—
0
0
38
236
1.62
2.11
1.5
1.5
—
—
—
0
0
18
88
2.06
2.11
1.2
1.1
57.25
36.74
mg/l
0.38
12
69
5
10
5.01
2.07
1.2
1.2
—
—
—
0
0
49
326
1.52
2.05
3.5
2.2
122.33
129.37
g/l
1.71
36
232
29
169
1.73
2.04
1.0
1.0
2.03
1.86
u/ml
0.05
12
68
76
552
1.39
2.03
2.5
2.5
10.25
10.28
g/l
0.02
66
487
31
185
1.69
2.01
1.3
1.2
2.71
5.90
u/ml
1.09
14
81
150
1208
1.26
1.96
4.7
3.4
1.23
1.23
mmol/l
0.12
132
1021
41
266
1.55
1.93
1.8
2.0
5.43
5.37
mmol/24h
0.03
32
229
41
267
1.55
1.90
4.1
2.4
—
—
—
0
0
14
65
2.16
1.88
3.6
3.5
7.42
7.43
ph
—
5
23
26
151
1.73
1.87
6.4
4.7
8.03
7.09
mmol/l
0.43
20
127
8
28
2.87
1.86
2.1
1.3
—
—
—
0
0
5
12
4.18
1.82
1.4
1.2
—
—
—
0
0
27
160
1.70
1.82
1.1
1.1
—
—
—
0
0
1484
14405
1.17
1.77
5.7
5.0
2.59
2.74
mmol/l
7.81
1376
13103
38
248
1.54
1.76
1.3
1.3
11.67
10.70
u/l
0.18
33
194
9
36
2.51
1.74
1.1
1.3
—
1.17
%
—
0
6
39
258
1.52
1.71
1.4
1.6
—
—
—
0
0
5
13
3.85
1.71
1.8
3.5
0.40
0.54
u/field
—
5
13
21
118
1.79
1.70
2.4
1.5
—
—
—
0
0
117
933
1.27
1.69
2.8
2.7
4.09
4.75
e9/l
0.67
97
725
13
62
2.10
1.65
1.8
2.7
2006.92
1860.00
ml
0.16
13
51
20
112
1.79
1.64
2.2
1.6
9.32
11.21
%
0.99
20
112
65
479
1.37
1.64
1.1
1.1
—
—
—
0
0
105
830
1.28
1.64
1.3
1.3
48.70
56.83
au/ml
—
7
55
115
921
1.27
1.62
2.4
2.4
15.63
26.50
au/ml
—
10
64
408
3670
1.14
1.61
1.4
1.4
—
—
—
0
0
8
32
2.51
1.59
1.3
1.5
54.13
92.75
nmol/24h
—
8
32
49
347
1.42
1.56
1.5
1.7
10765.97
14960.49
e6/l
0.49
30
253
13
64
2.04
1.54
2.6
3.1
—
—
—
0
0
44
307
1.44
1.52
4.3
2.4
14.51
16.01
%
1.80
24
158
20
115
1.75
1.52
2.3
2.3
5.40
2.07
u/field
—
10
41
17
93
1.84
1.51
2.0
1.5
0.86
0.99
g/l
1.23
17
93
64
478
1.35
1.51
2.6
2.4
37.80
37.44
g/l
0.19
54
413
156
1306
1.21
1.48
1.4
1.4
—
—
—
0
0
24
147
1.64
1.47
1.3
1.4
0.17
0.33
nmol/l
1.80
15
113
23
140
1.65
1.45
2.6
2.4
1.34
1.17
g/24h
0.14
13
64
1437
13971
1.14
1.45
5.0
4.4
1.42
1.51
mmol/l
11.15
1330
12685
37
253
1.47
1.43
1.4
1.5
—
—
—
0
0
13
66
1.98
1.43
2.2
2.9
—
—
—
0
0
1447
14079
1.14
1.42
5.0
4.5
4.48
4.67
mmol/l
10.46
1347
12853
53
390
1.37
1.39
1.1
1.1
—
—
—
0
0
17
96
1.78
1.39
1.1
1.1
—
—
—
0
0
9
41
2.20
1.37
1.2
1.0
1174.33
1585.15
miu/ml
—
9
41
17
97
1.76
1.35
1.2
1.5
—
—
—
0
0
23
144
1.60
1.32
1.5
1.5
—
—
—
0
0
19
114
1.67
1.28
1.1
1.1
0.30
3.69
u/ml
—
5
44
24
154
1.57
1.26
3.8
3.7
—
—
—
0
0
33
228
1.46
1.24
1.4
1.5
—
—
—
0
0
6
25
2.40
1.24
1.0
1.1
—
—
—
0
0
8
37
2.17
1.21
1.8
1.2
2.15
2.12
umol/l
—
8
32
77
960
0.79
1.20
1.2
1.4
—
—
—
0
0
33
230
1.44
1.20
3.2
2.9
—
—
—
0
0
53
401
1.33
1.20
3.5
2.5
—
—
—
0
0
149
1273
1.19
1.18
5.0
3.5
—
—
—
0
0
27
182
1.49
1.16
1.5
1.1
5.41
2.39
u/ml
0.25
14
83
250
2228
1.14
1.15
3.1
3.1
0.68
0.77
ug/l
1.22
171
1484
12
65
1.85
1.13
1.3
1.9
9.92
9.49
mmol/l
0.15
12
65
93
763
1.23
1.13
2.4
2.2
12.27
12.49
nmol/l
0.09
83
674
11
58
1.90
1.12
1.6
1.4
156.71
151.52
pmol/l
0.05
11
58
16
96
1.67
1.10
2.6
2.3
—
—
—
0
0
36
260
1.39
1.10
1.3
1.2
—
—
—
0
0
8
41
1.96
1.09
1.8
1.8
—
—
—
0
0
21
136
1.55
1.08
1.0
1.2
—
—
—
0
0
13
74
1.76
1.06
1.5
2.0
0.25
0.21
e9/l
0.33
13
67
21
137
1.54
1.05
1.3
1.2
—
32.60
—
0
5
7
33
2.13
1.05
1.7
1.7
—
—
—
0
0
110
927
1.20
1.04
1.4
1.3
—
—
—
0
0
24
162
1.49
1.04
1.4
1.6
69.69
62.95
%
0.30
13
103
59
464
1.28
1.04
1.2
1.3
32.53
31.93
iu/l
0.05
51
391
19
123
1.55
0.99
1.1
1.0
1.13
2.57
u/ml
—
5
56
44
336
1.32
0.97
1.8
1.8
3.25
5.04
iu/l
1.03
12
106
24
165
1.46
0.97
1.3
1.0
3.82
5.17
u/ml
0.23
13
73
17
108
1.58
0.96
1.1
1.1
—
—
—
0
0
75
615
1.23
0.95
4.9
3.9
—
—
—
0
0
11
62
1.78
0.94
1.2
1.2
—
0.43
g/l
—
0
5
40
305
1.32
0.91
2.4
2.3
142.25
73.61
ug/min
0.56
27
183
104
886
1.18
0.90
1.3
1.2
134.65
154.26
iu/ml
0.22
37
330
42
323
1.31
0.90
1.5
1.3
436.81
550.59
mg/l
2.11
42
306
23
160
1.44
0.89
1.2
1.1
0.30
1.58
u/ml
—
7
60
12
71
1.69
0.89
1.9
1.5
—
—
—
0
0
10
56
1.79
0.88
1.8
1.3
—
—
—
0
0
8
43
1.86
0.87
1.6
1.3
—
—
—
0
0
19
128
1.49
0.86
1.4
1.3
20.37
31.51
%
0.61
11
81
8
45
1.78
0.84
1.4
1.8
14.55
14.83
pmol/l
—
8
35
23
166
1.39
0.75
1.3
1.3
—
—
—
0
0
13
83
1.57
0.75
2.3
1.6
87.92
80.14
umol/l
0.37
13
83
13
83
1.57
0.75
1.4
1.3
—
—
—
0
0
20
141
1.42
0.74
1.3
1.8
—
—
—
0
0
36
281
1.29
0.73
1.5
1.3
154.06
422.06
e6/l
0.73
31
232
36
281
1.29
0.73
1.4
1.3
19.93
37.65
e6/l
0.28
29
224
26
194
1.35
0.71
2.3
1.8
—
—
—
0
0
20
143
1.40
0.70
1.1
1.0
4.35
2.18
u/ml
—
5
70
5
27
1.85
0.68
3.6
7.3
—
—
—
0
0
7
42
1.67
0.68
1.7
1.2
3.66
2.85
mmol/l
—
7
36
20
144
1.39
0.68
1.8
2.0
—
—
—
0
0
20
144
1.39
0.68
1.0
1.2
—
—
—
0
0
64
539
1.19
0.67
5.4
4.1
24.47
25.02
mmol/l
0.93
59
499
5
28
1.79
0.66
1.4
1.3
—
—
—
0
0
10
62
1.62
0.65
5.7
3.9
—
—
—
0
0
10
62
1.62
0.65
1.1
1.2
—
71.00
%
—
0
9
25
190
1.32
0.62
1.1
1.1
99.00
3030.67
iu/ml
—
5
42
10
63
1.59
0.61
1.2
2.5
1138.40
900.73
u/ml
—
10
63
21
156
1.35
0.61
1.5
2.3
—
—
—
0
0
13
88
1.48
0.60
4.6
6.6
—
—
—
0
0
8
52
1.54
0.59
3.4
2.3
—
—
—
0
0
0
22
0.00
0.59
0.0
1.0
—
—
—
0
0
33
267
1.24
0.54
2.0
1.5
—
—
—
0
0
32
258
1.24
0.54
1.9
1.7
37.00
41.50
nmol/l
0.67
32
247
22
169
1.31
0.53
1.7
1.5
—
—
—
0
0
10
66
1.52
0.52
1.8
1.3
—
—
—
0
0
27
214
1.27
0.52
2.2
1.4
—
—
—
0
0
9
63
1.43
0.52
1.1
1.8
—
—
—
0
0
44
370
1.19
0.51
3.3
3.2
0.87
0.82
nmol/l
0.36
36
278
13
93
1.40
0.48
1.2
1.1
—
—
—
0
0
10
143
0.70
0.47
1.3
1.4
—
—
—
0
0
7
47
1.49
0.47
4.6
1.7
—
—
—
0
0
10
68
1.47
0.47
2.7
2.3
506.80
500.85
min
—
10
46
10
142
0.70
0.46
1.4
1.4
—
—
—
0
0
17
130
1.31
0.44
2.2
1.2
—
—
—
0
0
5
32
1.56
0.42
1.0
1.1
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
3.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
5
34
1.47
0.40
1.0
1.4
—
—
—
0
0
22
177
1.25
0.40
1.6
1.3
21395.33
102133.04
e6/l
1.23
15
105
0
18
0.00
0.40
0.0
2.4
—
—
—
0
0
165
1540
1.08
0.40
5.9
4.3
—
—
—
0
0
9
68
1.33
0.37
1.4
1.5
1.16
1.23
nmol/l
—
9
55
13
98
1.33
0.37
3.4
1.9
37.58
38.23
%
0.06
13
98
11
147
0.75
0.37
1.4
1.5
—
—
—
0
0
445
4605
0.96
0.36
3.5
2.9
—
—
—
0
0
6
44
1.36
0.34
1.3
2.1
—
—
—
0
0
6
47
1.28
0.32
1.5
2.3
—
—
—
0
0
34
295
1.16
0.31
1.9
1.5
—
—
—
0
0
34
295
1.16
0.31
2.0
1.5
—
—
—
0
0
34
296
1.15
0.30
2.0
1.5
—
—
—
0
0
16
129
1.24
0.30
1.6
1.3
—
—
—
0
0
11
141
0.78
0.29
1.0
1.0
—
—
—
0
0
34
298
1.14
0.28
2.0
1.5
—
—
—
0
0
23
195
1.18
0.28
1.6
1.3
1880.22
1678.07
e6/l
0.17
18
142
12
94
1.28
0.28
1.1
1.1
—
—
—
0
0
13
104
1.25
0.26
1.5
1.1
9.62
12.16
u/l
0.45
13
97
11
86
1.28
0.26
2.6
1.5
17.03
18.42
nmol/l
0.28
11
77
5
73
0.68
0.26
1.0
1.1
—
15.48
—
0
21
23
197
1.17
0.26
1.9
1.7
—
—
—
0
0
20
169
1.19
0.26
1.9
1.4
—
—
—
0
0
9
74
1.22
0.25
1.3
1.4
6.93
8.85
ug/l
—
9
62
10
78
1.28
0.24
1.4
1.4
—
—
—
0
0
18
152
1.19
0.23
1.0
1.3
7.29
7.52
mmol/l
0.13
18
129
0
11
0.00
0.21
0.0
5.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.08
—
0
12
0
13
0.00
0.21
0.0
1.0
—
10.80
—
0
5
83
781
1.07
0.20
1.7
1.6
—
—
—
0
0
6
49
1.23
0.20
1.3
1.2
69.63
53.30
%
—
6
42
6
50
1.20
0.19
1.2
1.1
—
—
—
0
0
24
212
1.13
0.19
2.3
2.7
—
—
—
0
0
6
53
1.13
0.18
2.0
1.6
—
—
—
0
0
36
394
0.91
0.18
1.2
1.3
—
—
—
0
0
5
67
0.75
0.17
1.4
1.2
—
—
—
0
0
18
158
1.14
0.16
1.2
1.3
288.50
274.64
mosm/kgh2o
—
10
115
16
183
0.87
0.16
1.0
1.2
—
—
—
0
0
17
149
1.14
0.15
1.5
1.3
6.43
6.60
mmol/l
0.11
17
142
10
83
1.21
0.15
2.6
2.6
—
—
—
0
0
53
498
1.07
0.14
12.2
11.0
—
—
—
0
0
17
150
1.13
0.14
1.3
1.3
165975.00
87353.24
e6/l
—
8
105
19
172
1.11
0.11
1.1
1.1
—
—
—
0
0
19
172
1.11
0.11
1.1
1.1
—
—
—
0
0
19
173
1.10
0.10
1.1
1.3
—
—
—
0
0
183
1870
0.98
0.10
5.0
4.6
33.86
33.42
%
0.22
132
1205
5
44
1.14
0.10
1.2
1.3
—
—
—
0
0
5
46
1.09
0.09
1.2
1.1
—
—
—
0
0
42
399
1.05
0.09
1.1
1.1
—
—
—
0
0
6
58
1.03
0.08
1.5
1.2
131.83
154.55
mmol/24h
—
6
58
7
68
1.03
0.07
1.6
1.3
135.14
140.93
nmol/l
—
7
68
27
254
1.06
0.07
1.2
1.2
—
—
—
0
0
18
167
1.08
0.07
1.3
1.2
—
—
—
0
0
8
91
0.88
0.06
1.0
1.1
—
—
—
0
0
15
139
1.08
0.05
1.0
1.1
—
—
—
0
0
17
159
1.07
0.05
1.7
1.4
—
—
—
0
0
18
169
1.07
0.05
2.4
2.8
—
—
—
0
0
13
121
1.07
0.03
1.1
1.2
—
—
—
0
0
60
588
1.02
0.03
1.7
1.8
—
—
—
0
0
19
199
0.95
0.03
1.2
1.1
—
12.08
—
0
10
69
680
1.02
0.02
1.6
1.5
—
—
—
0
0
21
217
0.97
0.01
1.9
2.0
—
—
—
0
0
20
202
0.99
0.00
5.8
4.6
350.80
350.05
umol/l
0.01
20
174
0
5
0.00
0.00
0.0
2.4
—
213.00
—
0
5
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.7
—
8.60
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.0
—
1.94
—
0
9
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
6.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
78
0.90
-0.00
2.0
1.4
1.50
1.56
g/l
—
7
78
0
8
0.00
-0.00
0.0
1.1
—
92.50
—
0
8
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
14.16
—
0
7
0
7
0.00
-0.00
0.0
5.0
—
11.86
—
0
7
0
8
0.00
-0.00
0.0
1.6
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint K11_GALLBLAOTH and mortality.

Females

Parameter HR [95% CI] p-value
K11_GALLBLAOTH 1.493 [1.32, 1.69] < 0.001
Birth year 0.991 [0.98, 1.0] 0.034

During the follow-up period (1.1.1998 — 31.12.2019), 860 out of 3457 females with K11_GALLBLAOTH died.

Males

Parameter HR [95% CI] p-value
K11_GALLBLAOTH 1.511 [1.32, 1.74] < 0.001
Birth year 0.989 [0.98, 1.0] 0.022

During the follow-up period (1.1.1998 — 31.12.2019), 816 out of 2490 males with K11_GALLBLAOTH died.

Mortality risk

Mortality risk for people of age

years, who have K11_GALLBLAOTH.

N-year risk Females Males
1 0.177% 0.305%
5 0.953% 1.729%
10 1.97% 4.354%
15 3.672% 8.803%
20 6.419% 14.59%

Relationships between endpoints

Index endpoint: K11_GALLBLAOTH – Other diseases of gallbladder

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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