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This is a non-core endpoint: only basic statistics are computed.

Malignant neoplasm of accessory sinuses

DOID Endpoint Browser

C3_ACCESSORY_SINUS

paranasal sinus neoplasm: A benign or malignant neoplasm that affects the paranasal sinuses. Representative examples of benign neoplasms include Schneiderian papilloma and salivary gland-type adenoma. Representative examples of malignant neoplasms include carcinoma and lymphoma.

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Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C31
  • Cause of death: ICD-9 — 160
  • Cause of death: ICD-8 — 160
  • Cause of death: excluded ICD-9 — 160[0-1]
  • Cause of death: excluded ICD-8 — 160[0-1]
  • Cancer registry: Topography ICD-O-3 — C31
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

83

4. Check minimum number of events

None

83

5. Include endpoints

None

83

6. Filter based on genotype QC (FinnGen only)

79

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 79 32 47
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 64.66 62.68 66.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
83
Matched controls
830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
130
Kela drug reimbursment
Malignant tumour
+∞
44.9
39
*
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
+∞
36.1
32
*
A03FA01
ATC
metoclopramide; systemic, rectal
15.2
34.0
40
48
WF002
NOMESCO Finland
Radical radiotherapy
196.6
27.5
27
*
N02AA05
ATC
oxycodone; systemic
10.8
25.7
38
60
H02AB02
ATC
dexamethasone; systemic
117.1
24.2
25
*
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
23.0
21
*
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
+∞
21.8
20
*
WF003
NOMESCO Finland
Adjuvant radiotherapy
+∞
21.8
20
*
8070/3-C31.0
ICD-O-3
Squamous cell carcinoma, NOS, of maxillary sinus
+∞
20.7
19
*
C31.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of accessory sinuses
+∞
19.5
18
*
WZC00
NOMESCO Finland
Treatment plan or consultation
7.2
18.6
46
122
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
+∞
18.4
17
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
17.2
17.9
29
25
DHA10
NOMESCO Finland
Biopsy of cavity of nose
80.8
17.6
19
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
17.3
16
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
17.3
16
*
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
+∞
17.3
16
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
210.6
17.2
17
*
UDM02
NOMESCO Finland
Sinoscopy
48.4
16.2
19
5
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
+∞
15.0
14
*
A04AA01
ATC
ondansetron; systemic, rectal
32.2
14.1
18
7
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
+∞
13.9
13
*
XX3DW
NOMESCO Finland
Time consuming IT work
17.1
13.9
22
17
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
+∞
12.8
12
*
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
+∞
12.8
12
*
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
+∞
12.8
12
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
12.8
12
*
JN4BD
NOMESCO Finland
Extensive body CT
20.5
12.3
18
11
Z51.5
ICD-10 Finland
Palliative care
23.3
12.2
17
9
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
36.0
12.1
15
5
SAA03
NOMESCO Finland
Extended examination of mouth
5.0
12.0
47
173
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
11.7
11
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
25.7
11.1
15
7
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
25.7
11.1
15
7
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.4
10.9
28
72
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
69.2
10.9
12
*
C31.9
ICD-10 Finland
Malignant neoplasm: Accessory sinus, unspecified
+∞
10.6
10
*
L03AA02
ATC
filgrastim; parenteral
+∞
10.6
10
*
EBB10
NOMESCO Finland
Insertion of dental implant
+∞
10.6
10
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
9.0
10.2
22
32
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
12.4
10.1
18
18
WX402
NOMESCO Finland
General anaesthesia
5.2
9.9
25
63
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
20.7
9.8
14
8
DPA30
NOMESCO Finland
Sphenotomy
112.3
9.6
10
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
112.3
9.6
10
*
EBB15
NOMESCO Finland
Insertion of dental implant abutment
+∞
9.6
9
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
+∞
9.6
9
*
D38.50
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of maxillary sinus
+∞
9.6
9
*
EEB10
NOMESCO Finland
Maxillectomy
+∞
9.6
9
*
C31.1
ICD-10 Finland
Malignant neoplasm: Ethmoidal sinus
+∞
9.6
9
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
+∞
9.6
9
*
EEB00
NOMESCO Finland
Partial excision of maxilla
+∞
9.6
9
*
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
+∞
9.6
9
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
41.7
9.3
11
*
WX408
NOMESCO Finland
General anesthesy, balanced
4.4
8.9
30
95
WW500
NOMESCO Finland
Blood transfusion
23.0
8.8
12
6
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
99.8
8.6
9
*
L03AA13
ATC
pegfilgrastim; parenteral
99.8
8.6
9
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
99.8
8.6
9
*
A04AD12
ATC
aprepitant; systemic
+∞
8.5
8
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
+∞
8.5
8
*
EBB11
NOMESCO Finland
Insertion of additional dental implant in one session
+∞
8.5
8
*
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
8.5
8
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
8.3
20
48
GBB00
NOMESCO Finland
Tracheostomy
37.4
8.3
10
*
WZC30
NOMESCO Finland
Teaching
4.8
8.2
22
58
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
28.0
7.8
10
*
EP1AE
NOMESCO Finland
Neck ultrasound examination
12.6
7.6
13
12
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
87.6
7.5
8
*
ZZC00
NOMESCO Finland
Graft of fascia
+∞
7.4
7
*
AAE99
NOMESCO Finland
Other operation by cranial base approach
+∞
7.4
7
*
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
+∞
7.4
7
*
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
+∞
7.4
7
*
ZX095
NOMESCO Finland
Combined chemoradiotherapy
+∞
7.4
7
*
A07AA02
ATC
nystatin; oral
8.9
7.3
15
20
TPH07
NOMESCO Finland
Cathetrisation of artery
5.0
6.9
17
41
SBB10
NOMESCO Finland
Dental impressions
8.1
6.9
15
22
ZXC95
NOMESCO Finland
Use of surgical navigator
43.8
6.9
8
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
9.4
6.6
13
16
DHB40
NOMESCO Finland
Conchotomy
75.4
6.5
7
*
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
75.4
6.5
7
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
QAB10
NOMESCO Finland
Major dressing of wound of skin of head or neck
+∞
6.3
6
*
SPA10
NOMESCO Finland
Setting attachments on tooth or implanted bracket or imblant based structures
+∞
6.3
6
*
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
6.3
6
*
ZX070
NOMESCO Finland
Intensity modified radiotherapy
+∞
6.3
6
*
AAG50
NOMESCO Finland
Stereotactic intracranial radiotherapy
+∞
6.3
6
*
GD6AD
NOMESCO Finland
CT of chest and neck
+∞
6.3
6
*
ZZF00
NOMESCO Finland
Graft of adipose tissue
+∞
6.3
6
*
R22.0
ICD-10 Finland
Localized swelling, mass and lump, head
16.6
6.1
9
6

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
37
18
36.29
51.72
2.1
1.3
—
—
—
0
0
33
76
6.55
14.98
2.8
1.6
—
—
—
0
0
22
38
7.52
13.05
2.4
2.3
0.24
0.23
g/l
0.39
22
32
48
186
4.75
11.33
4.1
1.6
—
—
—
0
0
26
83
4.11
7.51
2.9
1.8
—
—
—
0
0
54
287
3.52
7.07
9.6
4.7
1.22
1.21
mmol/l
0.64
43
242
48
255
3.09
5.97
8.5
4.6
1.22
1.21
mmol/l
0.18
43
228
14
26
6.25
5.52
6.6
7.4
1.28
1.40
%
0.18
14
26
14
26
6.25
5.52
6.9
7.4
0.56
0.68
%
0.39
14
26
21
71
3.62
5.46
3.7
4.8
0.98
1.04
mmol/l
0.37
21
63
36
172
2.93
5.28
4.3
1.9
—
—
—
0
0
5
0
+∞
5.26
5.8
0.0
0.42
—
umol/l
—
5
0
11
18
6.86
4.79
5.2
12.0
—
—
—
0
0
32
150
2.84
4.79
7.9
3.3
—
—
—
0
0
14
42
3.81
4.26
1.4
1.1
—
—
—
0
0
28
132
2.69
4.06
7.0
2.4
86.21
88.69
%
0.25
28
126
6
5
12.78
3.82
1.7
1.8
—
—
—
0
0
13
37
3.97
3.60
7.6
6.8
—
—
—
0
0
16
59
3.12
3.56
5.3
4.8
104.31
104.19
mmol/l
0.03
16
59
31
165
2.40
3.42
7.3
2.9
7.42
7.40
ph
—
10
24
46
291
2.30
3.41
6.9
13.4
1.21
1.34
inr
0.41
14
84
18
75
2.79
3.24
1.4
1.5
—
—
—
0
0
5
5
10.52
3.01
1.0
2.4
52.60
72.00
mmol/l
—
5
5
5
5
10.52
3.01
1.6
1.0
—
—
—
0
0
12
39
3.42
2.92
8.2
3.7
1.23
1.21
mmol/l
0.65
12
33
48
618
0.47
2.74
3.8
5.1
2.85
2.68
mmol/l
0.40
43
566
26
142
2.21
2.62
18.5
5.0
—
—
—
0
0
10
31
3.52
2.62
1.5
1.6
—
—
—
0
0
44
299
2.00
2.47
6.2
5.5
0.57
0.59
e9/l
0.18
39
265
6
13
4.88
2.31
1.5
1.1
—
—
—
0
0
9
31
3.13
2.14
2.3
5.5
—
—
—
0
0
25
147
2.00
2.04
1.6
1.3
—
—
—
0
0
40
276
1.87
2.04
7.9
5.9
—
—
—
0
0
5
11
4.76
1.97
1.6
1.3
—
—
—
0
0
12
53
2.48
1.91
1.6
1.5
—
—
—
0
0
13
60
2.38
1.89
4.0
3.0
—
—
—
0
0
6
18
3.51
1.78
1.5
1.3
6172.00
385.00
e6/l
—
6
13
6
18
3.51
1.78
1.5
1.1
90.00
2.54
e6/l
—
6
13
12
218
0.47
1.59
2.2
3.2
—
—
—
0
0
12
59
2.21
1.52
1.6
1.5
—
—
—
0
0
22
137
1.82
1.49
2.5
2.3
—
—
—
0
0
47
571
0.59
1.49
4.1
6.2
39.84
40.61
mmol/mol
0.19
40
527
49
588
0.59
1.46
4.0
4.6
6.02
6.05
mmol/l
0.08
44
529
0
38
0.00
1.38
0.0
1.2
—
—
—
0
0
6
25
2.51
1.27
1.3
1.3
—
—
—
0
0
8
38
2.22
1.22
2.8
1.9
8.12
10.81
g/l
—
8
33
17
104
1.80
1.21
1.6
1.5
1.03
1.08
mg/l
0.05
12
73
47
382
1.53
1.08
4.1
4.3
—
—
—
0
0
0
29
0.00
1.00
0.0
1.3
—
—
—
0
0
6
27
2.31
0.95
1.8
2.2
—
—
—
0
0
0
24
0.00
0.80
0.0
7.2
—
—
—
0
0
0
26
0.00
0.80
0.0
1.0
—
—
—
0
0
7
41
1.77
0.72
4.6
1.2
—
—
—
0
0
22
284
0.69
0.71
4.9
3.5
0.00
0.00
estimate
—
8
48
5
28
1.83
0.67
1.2
3.7
—
—
—
0
0
12
79
1.61
0.67
1.7
1.4
—
—
—
0
0
8
50
1.66
0.63
1.1
1.4
—
—
—
0
0
22
278
0.72
0.62
5.5
5.1
0.00
0.00
estimate
—
8
50
22
275
0.73
0.57
4.9
3.5
0.00
0.00
estimate
—
8
56
7
47
1.53
0.49
1.7
1.3
—
—
—
0
0
19
152
1.32
0.42
2.1
1.9
3.11
3.17
mg/l
0.08
14
130
0
18
0.00
0.40
0.0
1.3
—
0.27
—
0
18
0
19
0.00
0.39
0.0
1.3
—
1.30
—
0
19
9
125
0.69
0.38
1.8
3.2
—
—
—
0
0
51
550
0.81
0.35
5.7
4.4
2.13
1.96
mu/l
0.32
44
489
6
46
1.33
0.34
12.8
3.6
—
—
—
0
0
7
52
1.38
0.32
1.6
1.7
143.71
79.33
ug/g
—
7
41
23
264
0.82
0.28
2.0
1.8
80.73
96.57
pmol/l
0.77
13
134
23
199
1.22
0.27
3.2
4.0
—
—
—
0
0
65
620
1.22
0.26
24.5
11.6
—
—
—
0
0
5
38
1.34
0.23
1.4
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
16.05
—
0
11
0
10
0.00
0.21
0.0
2.7
—
729.40
—
0
5
0
12
0.00
0.21
0.0
2.0
—
105.42
—
0
12
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
4.13
—
0
12
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
6
76
0.77
0.16
1.0
1.2
—
—
—
0
0
48
503
0.89
0.15
34.1
15.3
330.75
332.37
g/l
0.65
48
496
15
168
0.87
0.13
2.4
2.3
329.80
13752.64
umol/l
1.58
15
144
14
157
0.87
0.12
6.5
3.6
—
—
—
0
0
5
45
1.12
0.10
2.2
2.3
4.82
4.46
kpa
—
5
39
5
47
1.07
0.09
1.6
3.1
9.27
4.39
e9/l
—
5
37
44
423
1.09
0.09
4.6
3.7
—
—
—
0
0
6
56
1.08
0.09
2.0
2.9
5.80
5.87
kpa
—
6
50
6
57
1.06
0.09
2.0
2.9
4.08
2.13
mmol/l
—
6
39
14
152
0.91
0.07
6.6
3.5
0.00
0.00
estimate
—
8
47
15
161
0.92
0.05
2.6
3.1
—
—
—
0
0
25
260
0.94
0.04
3.8
3.7
45.47
191.55
ng/l
0.57
19
188
50
503
0.98
0.00
38.7
13.7
16.14
15.34
%
0.35
50
489
63
635
0.97
0.00
34.9
13.9
73.63
81.75
umol/l
2.50
63
635
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
13.98
—
0
5
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
1.42
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
77.80
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
179.47
—
0
6
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
161.00
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_ACCESSORY_SINUS – Malignant neoplasm of accessory sinuses

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).