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This is a non-core endpoint: only basic statistics are computed.

See its core counterpart C3_ACCESSORY_SINUS_EXALLC for full statistics.

Malignant neoplasm of accessory sinuses

C3_ACCESSORY_SINUS

paranasal sinus neoplasm: A benign or malignant neoplasm that affects the paranasal sinuses. Representative examples of benign neoplasms include Schneiderian papilloma and salivary gland-type adenoma. Representative examples of malignant neoplasms include carcinoma and lymphoma.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 C31
  • Cause of death: ICD-9 160
  • Cause of death: ICD-8 160
  • Cause of death: excluded ICD-9 160[0-1]
  • Cause of death: excluded ICD-8 160[0-1]
  • Cancer registry: Topography ICD-O-3 C31
  • Cancer registry: Morphology ICD-O-3 ANY
  • Cancer registry: Behaviour codes 3

2 out of 7 registries used, show all original rules.

79

4. Check minimum number of events

None

79

5. Include endpoints

None

79

6. Filter based on genotype QC (FinnGen only)

79

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9

Similar endpoints

List of similar endpoints to Malignant neoplasm of accessory sinuses based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Similar with more cases:

Venn diagram with a set fully inside an highlighted set Similar with less cases:

None

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 79 32 47
Unadjusted period prevalence (%) 0.02 0.01 0.02
Median age at first event (years) 64.94 63.37 66.01

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
76
Matched controls
757
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C31.0
ICD-10 Finland
Malignant neoplasm: Maxillary sinus
409.8
28.8
27
*
130
Kela drug reimbursment
Malignant tumour
17.7
20.5
34
33
8070/3-C31.0
ICD-O-3
Squamous cell carcinoma, NOS, of maxillary sinus
+∞
19.6
18
*
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
+∞
18.5
17
*
UDH02
NOMESCO Finland
Rhinopharyngoscopy
20.1
17.1
26
19
WF003
NOMESCO Finland
Adjuvant radiotherapy
49.6
16.3
19
5
D14.0
ICD-10 Finland
Benign neoplasm: Middle ear, nasal cavity and accessory sinuses
+∞
16.2
15
*
D38.51
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of other accessory sinus
+∞
16.2
15
*
DHA10
NOMESCO Finland
Biopsy of cavity of nose
71.7
15.5
17
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
+∞
15.1
14
*
C31.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of accessory sinuses
183.7
15.0
15
*
UDM02
NOMESCO Finland
Sinoscopy
35.7
13.6
17
6
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
21.4
11.8
17
10
DM1DG
NOMESCO Finland
Paranasal sinuses and face area very extensive MRI examination with high intensity magnet
140.2
11.8
12
*
A03FA01
ATC
metoclopramide; systemic, rectal
6.8
11.7
34
80
WF002
NOMESCO Finland
Radical radiotherapy
10.9
11.7
23
29
N02AA05
ATC
oxycodone; systemic
8.1
11.5
28
51
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
19.4
11.5
17
11
EP1CG
NOMESCO Finland
Extensive MRI examination of soft tissue of neck with high intesity magnet
51.4
11.3
13
*
DM1BD
NOMESCO Finland
Extensive CT of paranasal sinuses and face area
126.6
10.7
11
*
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
126.6
10.7
11
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
126.6
10.7
11
*
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
30.8
10.2
13
5
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
25.6
9.7
13
6
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
113.4
9.6
10
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
113.4
9.6
10
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
+∞
9.6
9
*
C31.9
ICD-10 Finland
Malignant neoplasm: Accessory sinus, unspecified
+∞
9.6
9
*
H02AB02
ATC
dexamethasone; systemic
8.1
9.2
21
34
SAA03
NOMESCO Finland
Extended examination of mouth
4.7
9.0
40
146
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
56.7
8.9
10
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
4.6
8.8
41
154
EEB00
NOMESCO Finland
Partial excision of maxilla
100.6
8.6
9
*
DMA00
NOMESCO Finland
Biopsy of maxillary antrum
100.6
8.6
9
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
12.1
8.5
15
15
PJD81
NOMESCO Finland
Excision of lymph nodes from upper part of neck
+∞
8.5
8
*
C31.1
ICD-10 Finland
Malignant neoplasm: Ethmoidal sinus
+∞
8.5
8
*
EEB10
NOMESCO Finland
Maxillectomy
+∞
8.5
8
*
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
+∞
8.5
8
*
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
50.3
7.9
9
*
WW500
NOMESCO Finland
Blood transfusion
15.5
7.7
12
9
D38.50
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of maxillary sinus
88.2
7.6
8
*
AAE99
NOMESCO Finland
Other operation by cranial base approach
+∞
7.4
7
*
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
10.9
7.1
13
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.9
7.0
24
65
A04AA02
ATC
granisetron; systemic, transdermal
8.2
6.9
15
22
GBB00
NOMESCO Finland
Tracheostomy
25.1
6.8
9
*
XX3DW
NOMESCO Finland
Time consuming IT work
5.8
6.7
19
41
Z51.5
ICD-10 Finland
Palliative care
8.3
6.6
14
20
DPA30
NOMESCO Finland
Sphenotomy
75.9
6.5
7
*
DM1CG
NOMESCO Finland
Paranasal sinuses and face area extensive MRI examination with high intensity magnet
75.9
6.5
7
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.0
6.4
13
17
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
9.0
6.4
13
17
ZZQ20
NOMESCO Finland
Free microvascular graft of skin, muscle and bone
+∞
6.3
6
*
CCD60
NOMESCO Finland
Transnasal dacryocystorhinostomy
+∞
6.3
6
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
6.3
6
*
DHB40
NOMESCO Finland
Conchotomy
+∞
6.3
6
*
DNB30
NOMESCO Finland
Excision of lesion of ethmoidal sinus
+∞
6.3
6
*
DPB00
NOMESCO Finland
Partial excision of frontal sinus
+∞
6.3
6
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.2
6.3
20
49
A04AA01
ATC
ondansetron; systemic, rectal
6.9
6.2
15
26
A07AA02
ATC
nystatin; oral
7.5
6.2
14
22

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
33
54
9.78
21.38
2.1
1.5
—
—
—
0
0
32
79
6.13
13.42
2.9
1.5
—
—
—
0
0
25
88
3.69
6.22
3.0
2.1
—
—
—
0
0
18
53
4.10
5.71
1.8
4.2
1.7
0.5
%
1.28
11
13
19
61
3.78
5.34
2.4
4.1
1.4
0.8
%
0.44
14
19
5
0
+∞
5.26
5.8
0.0
0.4
—
umol/l
—
5
0
44
242
2.85
4.95
4.2
2.2
—
—
—
0
0
45
268
2.58
4.10
8.1
6.2
1.2
1.2
mmol/l
0.24
40
239
20
79
3.05
4.02
3.8
7.3
1.0
1.0
mmol/l
0.31
20
74
7
9
8.39
3.64
1.3
1.1
—
—
—
0
0
6
6
10.68
3.56
1.7
2.0
—
—
—
0
0
7
10
7.55
3.44
1.7
4.0
—
—
—
0
0
10
31
3.55
2.88
5.1
9.0
—
—
—
0
0
34
202
2.20
2.86
6.8
5.2
—
—
—
0
0
33
194
2.20
2.84
4.4
2.4
—
—
—
0
0
5
6
8.78
2.79
1.6
1.0
—
—
—
0
0
31
179
2.20
2.78
8.1
4.5
—
—
—
0
0
5
7
7.52
2.58
1.0
2.0
52.6
58.3
mmol/l
—
5
7
5
7
7.52
2.58
1.2
1.1
—
—
—
0
0
11
239
0.37
2.47
4.5
4.0
—
—
—
0
0
43
293
2.03
2.42
6.1
6.3
0.0
0.0
e9/l
0.89
38
253
17
80
2.43
2.40
1.4
1.4
—
—
—
0
0
45
576
0.49
2.38
3.6
5.1
2.9
2.6
mmol/l
0.48
40
518
13
54
2.68
2.34
4.0
4.3
—
—
—
0
0
28
168
2.03
2.20
7.4
4.5
7.4
7.4
ph
—
9
34
6
14
4.54
2.19
1.5
1.1
—
—
—
0
0
42
293
1.93
2.13
6.1
6.2
0.6
0.6
e9/l
0.53
37
253
35
240
1.82
1.80
6.7
9.4
1.3
1.2
inr
0.19
11
73
11
48
2.50
1.80
7.1
10.1
—
—
—
0
0
11
49
2.45
1.72
8.8
5.0
1.2
1.2
mmol/l
0.52
11
43
5
14
3.74
1.64
1.6
1.7
—
—
—
0
0
11
202
0.47
1.51
2.0
3.0
—
—
—
0
0
6
22
2.86
1.46
1.8
3.6
27.1
25.9
mmol/l
—
6
22
24
156
1.77
1.42
19.4
7.1
—
—
—
0
0
9
41
2.35
1.42
1.6
1.7
—
—
—
0
0
44
536
0.60
1.41
4.0
6.1
39.9
40.8
mmol/mol
0.21
38
497
9
42
2.29
1.39
2.3
4.9
—
—
—
0
0
46
552
0.60
1.35
3.9
4.7
6.0
6.0
mmol/l
0.01
41
502
6
26
2.41
1.21
1.8
3.2
—
—
—
0
0
22
149
1.66
1.11
1.5
1.3
—
—
—
0
0
13
75
1.88
1.11
5.8
8.7
104.5
103.4
mmol/l
0.28
13
69
7
36
2.03
1.00
1.9
3.2
—
7.5
—
0
5
0
31
0.00
0.99
0.0
1.2
—
—
—
0
0
6
27
2.32
0.96
1.3
1.5
—
—
—
0
0
11
64
1.84
0.91
1.6
1.6
—
—
—
0
0
12
74
1.73
0.84
1.4
1.3
—
—
—
0
0
11
66
1.77
0.84
1.6
1.6
—
—
—
0
0
22
289
0.67
0.81
4.9
4.4
0.0
0.0
estimate
—
8
61
0
24
0.00
0.80
0.0
1.3
—
—
—
0
0
0
24
0.00
0.80
0.0
1.0
—
—
—
0
0
22
286
0.68
0.76
5.5
6.0
0.0
0.0
estimate
—
8
63
22
284
0.69
0.72
4.9
4.4
0.0
0.0
estimate
—
7
65
5
27
1.91
0.69
1.2
5.0
—
—
—
0
0
8
49
1.70
0.64
1.1
1.5
—
—
—
0
0
0
20
0.00
0.61
0.0
3.5
—
32.5
—
0
11
0
20
0.00
0.61
0.0
17.3
—
—
—
0
0
9
133
0.64
0.58
1.8
3.8
—
—
—
0
0
13
176
0.69
0.53
2.4
3.5
—
—
—
0
0
44
393
1.27
0.43
4.0
4.7
—
—
—
0
0
0
17
0.00
0.41
0.0
1.3
—
0.3
—
0
17
0
17
0.00
0.41
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.3
—
1.4
—
0
18
11
81
1.42
0.38
1.7
1.6
—
—
—
0
0
47
511
0.80
0.37
5.8
4.6
2.1
2.0
mu/l
0.11
40
451
6
41
1.50
0.37
3.2
2.1
—
—
—
0
0
20
167
1.26
0.33
2.3
2.9
—
—
—
0
0
21
245
0.81
0.31
1.9
1.9
77.7
96.0
pmol/l
0.88
12
119
5
74
0.65
0.27
1.0
1.4
—
—
—
0
0
48
512
0.84
0.26
29.4
16.3
36.8
40.2
%
1.58
34
339
5
37
1.37
0.24
1.4
1.1
—
—
—
0
0
16
135
1.23
0.24
4.8
6.1
—
—
—
0
0
5
38
1.34
0.24
2.0
3.8
0.5
0.1
e6/l
—
5
38
14
166
0.81
0.23
6.5
4.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.7
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
21
185
1.18
0.21
3.3
4.1
—
—
—
0
0
6
52
1.17
0.19
1.8
1.8
162.7
191.3
ug/g
—
6
43
5
69
0.71
0.17
2.0
1.3
—
—
—
0
0
14
161
0.84
0.17
6.6
4.4
0.0
0.0
estimate
—
8
60
44
464
0.88
0.16
39.7
19.9
14.4
13.9
%
1.81
44
452
61
593
1.13
0.11
25.1
15.2
—
—
—
0
0
11
96
1.17
0.11
2.0
1.4
2.5
2.9
g/l
0.32
11
62
15
165
0.89
0.10
2.4
2.8
329.8
12440.8
umol/l
1.57
15
138
5
47
1.07
0.09
2.2
5.5
—
—
—
0
0
23
246
0.91
0.09
3.9
4.2
47.0
37.9
ng/l
0.11
18
178
5
48
1.04
0.09
2.2
5.5
4.1
1.8
mmol/l
—
5
33
6
56
1.08
0.09
12.8
4.3
—
—
—
0
0
16
147
1.11
0.08
1.8
1.9
3.1
3.5
mg/l
0.51
11
134
45
464
0.93
0.07
34.4
21.1
330.5
331.9
g/l
0.50
45
459
59
601
0.93
0.05
35.4
19.1
73.6
82.0
umol/l
2.33
59
601
41
405
1.03
0.00
4.5
4.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
9
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
37.4
—
1081.2
—
0
5
0
5
0.00
0.00
0.0
20.8
—
756.8
—
0
5
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
0.00
0.0
2.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
12.3
—
0
6
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
10.8
—
0
5
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
168.2
—
0
5
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
16.8
—
0
7
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
2.4
—
13.1
—
0
8
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: C3_ACCESSORY_SINUS – Malignant neoplasm of accessory sinuses

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).