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Traumatic amputation of wrist and hand

ST19_TRAUMAT_AMPUT_WRIST_HAND

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S68
  • Cause of death: ICD-10 S68

2 out of 7 registries used, show all original rules.

1599

4. Check minimum number of events

None

1599

5. Include endpoints

None

1599

6. Filter based on genotype QC (FinnGen only)

1599

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_WRIST_HAND

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S6
Name in latin
Amputatio traumatica carpi/manus

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 1599 256 1343
Unadjusted period prevalence (%) 0.51 0.09 0.59
Median age at first event (years) 54.32 50.59 55.03

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1458
Matched controls
14578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
W31
ICD-10 Finland
Contact with other and unspecified machinery
217.0
323.0
594
46
S68.2
ICD-10 Finland
Traumatic amputation of two or more fingers alone (complete)(partial)
+∞
323.0
299
*
S68.1
ICD-10 Finland
Traumatic amputation of other single finger (complete)(partial)
+∞
323.0
945
*
NDQ48
NOMESCO Finland
Revision or amputation or exarticulation of finger
1895.6
319.8
299
*
S68.0
ICD-10 Finland
Traumatic amputation of thumb (complete)(partial)
+∞
260.4
242
*
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
14.0
203.1
371
348
NDQ20
NOMESCO Finland
Amputation of finger
258.0
179.9
181
8
S61.0
ICD-10 Finland
Open wound of finger(s) without damage to nail
9.5
115.7
254
318
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
23.2
115.4
169
82
S61.1
ICD-10 Finland
Open wound of finger(s) with damage to nail
29.7
115.3
157
59
NDJ64
NOMESCO Finland
Internal fixation of fracture of wrist or hand wire, rod, cerclage or pin
116.5
100.5
108
10
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
27.0
100.4
140
57
QCB00
NOMESCO Finland
Suture of skin of upper limb
69.2
95.1
109
17
S62.6
ICD-10 Finland
Fracture of other finger
28.8
94.2
129
49
X58
ICD-10 Finland
Exposure to other specified factors
4.6
87.0
349
940
W23
ICD-10 Finland
Caught, crushed, jammed or pinched in or between objects
74.8
86.5
98
14
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
41.8
75.2
94
24
WX204
NOMESCO Finland
Axillary plexus blockaced
10.9
72.1
143
144
ACB29
NOMESCO Finland
Suture of peripheral nerve other or unspecified
+∞
67.2
64
*
NDP32
NOMESCO Finland
Repair of finger or fingers by transplant of tissue
+∞
64.0
61
*
NDL32
NOMESCO Finland
Suture or reinsertion of tendon of wrist or hand, extensor tendon
103.4
63.4
69
7
W22
ICD-10 Finland
Striking against or struck by other object(s)
5.9
61.2
182
342
T92.6
ICD-10 Finland
Sequelae of crushing injury and traumatic amputation of upper limb
+∞
60.9
58
*
ZXD05
NOMESCO Finland
Urgent procedure
2.7
60.7
575
2846
J01DB01
ATC
cefalexin; oral
3.1
58.4
1249
9644
S68.3
ICD-10 Finland
Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
+∞
57.7
55
*
S67.0
ICD-10 Finland
Crushing injury of thumb and other finger(s)
579.9
57.0
56
*
X59
ICD-10 Finland
Exposure to unspecified factor
3.1
52.9
352
1375
W27
ICD-10 Finland
Contact with nonpowered hand tool
40.6
52.7
66
17
NDP12
NOMESCO Finland
Replantation of a digit
+∞
50.3
48
*
S61.8
ICD-10 Finland
Open wound of other parts of wrist and hand
24.4
49.3
70
30
NDL30
NOMESCO Finland
Suture or reinsertion of tendon of wrist or hand, flexor tendon
140.5
38.9
41
*
S66.3
ICD-10 Finland
Injury of extensor muscle and tendon of other finger at wrist and hand level
58.0
38.5
45
8
W45
ICD-10 Finland
Foreign body or object entering through skin
13.5
34.9
61
47
WX203
NOMESCO Finland
Infraclavicular plexus blockade
7.9
34.3
80
106
S18
ICPC
Laceration/cut
2.0
34.1
649
4155
S66.1
ICD-10 Finland
Injury of flexor muscle and tendon of other finger at wrist and hand level
344.9
34.1
34
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.7
33.8
259
1076
S64.4
ICD-10 Finland
Injury of digital nerve of other finger
334.4
33.0
33
*
R4120
NOMESCO Finland
Occupational therapy
4.0
32.4
139
378
M01AE01
ATC
ibuprofen; systemic, rectal
2.5
32.1
1287
10970
S68.8
ICD-10 Finland
Traumatic amputation of other parts of wrist and hand
+∞
30.3
29
*
S60.1
ICD-10 Finland
Contusion of finger(s) with damage to nail
13.9
29.6
51
38
S61.9
ICD-10 Finland
Open wound of wrist and hand, part unspecified
8.8
29.2
63
74
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
19.2
28.4
43
23
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
8.2
28.3
64
81
TQW40
NOMESCO Finland
Remowal of suture of skin
3.5
27.6
138
426
N02BE01
ATC
paracetamol; systemic, rectal
2.1
27.2
1193
9992
S62.5
ICD-10 Finland
Fracture of thumb
28.3
26.8
36
13
W24
ICD-10 Finland
Contact with lifting and transmission device(s), not elsewhere classified
22.3
25.7
37
17
QCE35
NOMESCO Finland
Repair of skin defect in upper limb after surgery or injury
+∞
25.1
24
*
S67.8
ICD-10 Finland
Crushing injury of other and unspecified parts of wrist and hand
243.8
23.7
24
*
ZXA05
NOMESCO Finland
Left side
1.9
20.9
360
2131
NDP18
NOMESCO Finland
Replantation of several digits
+∞
20.9
20
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.7
20.4
638
4569
N02AJ06
ATC
codeine and paracetamol; systemic
1.7
19.9
528
3593
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
4.3
19.6
74
179
NDL54
NOMESCO Finland
Tenolysis of hand
25.0
19.6
27
11
L12
ICPC
Hand/finger symptom/complaint
2.3
19.6
190
882
S61.7
ICD-10 Finland
Multiple open wounds of wrist and hand
40.7
19.5
24
6
S62.7
ICD-10 Finland
Multiple fractures of fingers
192.3
18.6
19
*
QCH00
NOMESCO Finland
Avulsion of finger nail
192.3
18.6
19
*
NDG76
NOMESCO Finland
Fusion of DIP joint
13.1
18.4
32
25
NDT10
NOMESCO Finland
Early operation for multiple trauma of hand and wrist
+∞
17.7
17
*
S62.1
ICD-10 Finland
Fracture of other carpal bone(s)
25.9
16.9
23
9
J01DA01
ATC
[U] cefalexin; systemic
1.6
16.6
820
6502
S62.3
ICD-10 Finland
Fracture of other metacarpal bone
9.1
16.0
33
37
W26
ICD-10 Finland
Contact with other sharp object(s)
12.4
15.9
28
23
W55
ICD-10 Finland
Bitten or struck by other mammals
5.5
15.3
45
84
ACC29
NOMESCO Finland
Reconstruction of peripheral nerve: other or unspecified
32.0
14.8
19
6
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
14.7
205
1108
SPAT1153
SPAT
Removal of sutures
1.6
14.2
436
3025
Y28
ICD-10 Finland
Contact with sharp object, undetermined intent
24.0
13.8
19
8
S62.0
ICD-10 Finland
Fracture of navicular [scaphoid] bone of hand
28.6
13.0
17
6
N02AX02
ATC
tramadol; systemic, rectal
1.5
12.9
575
4352
ZXA00
NOMESCO Finland
Right side
1.6
12.8
350
2345
S62.8
ICD-10 Finland
Fracture of other and unspecified parts of wrist and hand
32.3
12.6
16
5
S68.9
ICD-10 Finland
Traumatic amputation of wrist and hand, level unspecified
+∞
12.5
12
*
S63.3
ICD-10 Finland
Traumatic rupture of ligament of wrist and carpus
26.9
12.1
16
6
S62.2
ICD-10 Finland
Fracture of first metacarpal bone
47.1
11.9
14
*
QCE20
NOMESCO Finland
Excision and repair of scar or web of skin of upper limb
47.1
11.9
14
*
NDL40
NOMESCO Finland
Repair of tendon of finger with transplant
47.1
11.9
14
*
J01FF01
ATC
clindamycin; systemic
1.6
11.6
353
2424
ZXE00
NOMESCO Finland
One hour or less
1.5
11.5
493
3675
S66.0
ICD-10 Finland
Injury of long flexor muscle and tendon of thumb at wrist and hand level
+∞
11.5
11
*
T92.2
ICD-10 Finland
Sequelae of fracture at wrist and hand level
10.1
11.0
21
21
SPAT1211
SPAT
Application of soft bandage
2.1
10.8
119
582
ZXD35
NOMESCO Finland
Usual procedure
3.1
10.7
57
188
ZZA00
NOMESCO Finland
Split skin graft
3.0
10.5
58
196
NDP30
NOMESCO Finland
Repair of wrist or hand by transplant of tissue
+∞
10.4
10
*
NDJ60
NOMESCO Finland
Internal fixation of fracture of wrist or hand with screw
+∞
10.4
10
*
S68.4
ICD-10 Finland
Traumatic amputation of hand at wrist level
+∞
10.4
10
*
T15.0
ICD-10 Finland
Foreign body in cornea
2.7
10.2
69
265
WX110
NOMESCO Finland
Local anesthesy
1.4
10.2
883
7526
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
10.2
304
2068
W49
ICD-10 Finland
Exposure to other and unspecified inanimate mechanical forces
5.7
9.8
27
48
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
9.5
217
1374
QCH01
NOMESCO Finland
Excision of nail bed in finger
+∞
9.4
9
*
Z02.4
ICD-10 Finland
Examination for driving licence
1.5
9.2
371
2703
Y94.8
ICD-10 Finland
Other leisure activity accident
3.6
9.0
39
111
SPAT1263
SPAT
Sampling
1.4
8.8
503
3926
M01AH05
ATC
etoricoxib; oral
1.4
8.8
734
6135
S66.2
ICD-10 Finland
Injury of extensor muscle and tendon of thumb at wrist and hand level
27.7
8.5
11
*
NDQ60
NOMESCO Finland
Revision of amputation or exarticulation stump in wrist
+∞
8.3
8
*
S63.1
ICD-10 Finland
Dislocation of finger
10.8
8.3
15
14
W17
ICD-10 Finland
Other fall from one level to another
2.5
8.3
64
267
S60.0
ICD-10 Finland
Contusion of finger(s) without damage to nail
4.0
8.0
30
76
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
3.8
7.9
31
82
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.0
7.8
95
488
M79.6
ICD-10 Finland
Pain in limb
1.4
7.7
380
2868
NDE62
NOMESCO Finland
Plastic repair of ligament or capsule of joint of finger or metacarpal
18.5
7.6
11
6
W11
ICD-10 Finland
Fall on and from ladder
3.4
7.6
35
106
E923A
ICD-9 Finland
Accident caused by explosive material
4.7
7.5
24
52
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
7.5
314
2293
ACC99
NOMESCO Finland
Other operation for impaired function of peripheral nerve: other or unspecified
80.5
7.4
8
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
7.4
104
565
M01AB05
ATC
diclofenac; systemic, rectal
1.4
7.4
840
7303
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
7.3
281
2013
S69.7
ICD-10 Finland
Multiple injuries of wrist and hand
+∞
7.3
7
*
QCH05
NOMESCO Finland
Correction of deformity of finger nail
+∞
7.3
7
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
7.1
72
344
S01.0
ICD-10 Finland
Open wound of scalp
1.8
7.1
111
627
ZZR00
NOMESCO Finland
Flap of skin
3.1
7.0
36
118
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
7.0
696
5903
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
6.9
133
801
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.9
639
5354
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
6.8
320
2388
QCE99
NOMESCO Finland
Other excision or repair of lesion of skin of upper limb
5.7
6.8
18
32
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
6.8
134
812
S60.2
ICD-10 Finland
Contusion of other parts of wrist and hand
3.0
6.5
35
119
X78
ICD-10 Finland
Intentional self-harm by sharp object
10.1
6.5
12
12
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
6.5
427
3377
W00
ICD-10 Finland
Fall on same level involving ice and snow
1.8
6.5
118
697
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.5
864
7619
N03AX16
ATC
pregabalin; oral
1.5
6.5
261
1887
QCE30
NOMESCO Finland
Excision and repair of surgical scar in upper limb
70.1
6.4
7
*
QCG99
NOMESCO Finland
Other operation for chronic ulcer or fistula of skin
70.1
6.4
7
*
Y96.8
ICD-10 Finland
Other type of accident
6.6
6.3
15
23
S64.3
ICD-10 Finland
Injury of digital nerve of thumb
+∞
6.3
6
*
NDQ10
NOMESCO Finland
Amputation in wrist or hand
+∞
6.3
6
*
N03AX12
ATC
gabapentin; oral
1.6
6.2
177
1183
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.8
6.2
37
135
J01CF02
ATC
cloxacillin; systemic
2.9
6.1
35
122
M03BX02
ATC
tizanidine; oral
1.3
6.0
733
6350
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
6.0
442
3552
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.4
6.0
47
200

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_TRAUMAT_AMPUT_WRIST_HAND – Traumatic amputation of wrist and hand

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).