Hyperplasia of prostate

N14_PROSTHYPERPLA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only males

226837

2. Check conditions

None

226837

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 N40
  • Hospital discharge: ICD-9 600
  • Hospital discharge: ICD-8 600
  • Cause of death: ICD-10 N40
  • Cause of death: ICD-9 600
  • Cause of death: ICD-8 600

2 out of 7 registries used, show all original rules.

42330

4. Check minimum number of events

None

42330

5. Include endpoints

None

42330

6. Filter based on genotype QC (FinnGen only)

42330

Control definitions (FinnGen only)

Control exclude
N14_MALEGEN

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
N40-N51
Name in latin
Hyperplasia prostatae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 306982 - 306982
Only index persons 237063 - 237063
Unadjusted period prevalence (%)
Whole population 8.58 - 8.58
Only index persons 9.05 - 9.05
Median age at first event (years)
Whole population - - 69.45
Only index persons - - 68.69

-FinnGen-

Key figures

All Female Male
Number of individuals 42330 - 42330
Unadjusted period prevalence (%) 18.66 - 18.66
Median age at first event (years) 68.25 - 68.25

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4042
Matched controls
32609
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
KED22
NOMESCO Finland
Transurethral resection of prostate
221.1
323.0
546
23
KE1BE
NOMESCO Finland
Rectal ultrasound examinaiton of prostata
32.8
323.0
1460
552
N40
ICD-10 Finland
Hyperplasia of prostate
16384.0
323.0
4039
1697
G04CA02
ATC
tamsulosin; oral
8.3
323.0
2124
3827
UKC02
NOMESCO Finland
Cystoscopy
10.2
323.0
1186
1273
G04CA01
ATC
alfuzosin; oral
7.9
323.0
1476
2221
G04CA52
ATC
tamsulosin and dutasteride; systemic
13.3
323.0
945
729
XKD00
NOMESCO Finland
Uroflowmetry
29.4
323.0
2209
1285
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
23.0
323.0
1787
1087
R33
ICD-10 Finland
Retention of urine
13.9
306.5
577
385
G04CB02
ATC
dutasteride; oral
16.2
301.8
533
303
XJH00
NOMESCO Finland
Transanal ultrasonography
17.3
293.9
506
268
G04CB01
ATC
finasteride; oral (testosterone-5-alpha reductase inhibitors)
9.4
269.1
618
612
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
6.9
209.9
591
793
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
6.7
200.2
574
787
G04BD12
ATC
mirabegron; oral
7.9
180.2
456
516
J01MA02
ATC
ciprofloxacin; systemic
2.7
177.8
1742
7046
TKE00
NOMESCO Finland
Needle biopsy of prostate
16.2
143.1
250
132
KED33
NOMESCO Finland
Transurethral incision of prostate
50.3
138.1
179
30
XKD06
NOMESCO Finland
Physiologic investigation of micturition
16.8
138.1
238
121
N41.1
ICD-10 Finland
Chronic prostatitis
11.0
130.6
270
210
R35
ICD-10 Finland
Polyuria
5.8
128.5
404
610
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.2
127.0
444
761
R31
ICD-10 Finland
Unspecified haematuria
4.5
124.1
497
984
C61
ICD-10 Finland
Malignant neoplasm of prostate
4.3
118.7
503
1050
TKC22
NOMESCO Finland
Catheterisation instruction
17.5
118.7
201
97
KED52
NOMESCO Finland
Visual laser resection of prostate
342.1
114.1
124
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
4.2
104.6
454
964
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
5.4
96.1
321
517
J01EA01
ATC
trimethoprim; systemic
4.3
94.7
394
801
R39.1
ICD-10 Finland
Other difficulties with micturition
7.0
86.0
232
282
R86.0
ICD-10 Finland
Abnormal findings in specimens from male genital organs, abnormal level of enzymes
6.5
85.9
243
316
XKC03
NOMESCO Finland
Water cystometry
16.0
85.3
149
78
N47
ICD-10 Finland
Redundant prepuce, phimosis and paraphimosis
24.2
84.2
128
44
KGH10
NOMESCO Finland
Operation for phimosis
47.5
83.5
109
19
N41.0
ICD-10 Finland
Acute prostatitis
7.5
74.5
191
215
WX320
NOMESCO Finland
Spinalanesthesy
2.3
69.8
780
3073
G04BD08
ATC
solifenacin; oral
5.8
67.6
207
298
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
14.1
66.3
121
71
KE1DG
NOMESCO Finland
Very extensive MRI of prostate
8.6
64.0
150
146
U02
ICPC
Urinary frequency/urgency
5.0
62.8
218
364
U07
ICPC
Urine symptom/complaint other
6.4
62.5
179
236
N30.0
ICD-10 Finland
Acute cystitis
5.5
61.5
198
303
N41.9
ICD-10 Finland
Inflammatory disease of prostate, unspecified
8.2
56.1
134
135
N02BE01
ATC
paracetamol; systemic, rectal
1.8
55.0
3181
21790
U08
ICPC
Urinary retention
14.1
54.4
99
58
N32.0
ICD-10 Finland
Bladder-neck obstruction
17.9
51.2
85
39
XKD03
NOMESCO Finland
Urethral pressure profilometry
20.2
50.8
81
33
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.6
50.6
254
602
N43.4
ICD-10 Finland
Spermatocele
12.5
49.1
94
62
U05
ICPC
Urination problems other
5.8
49.0
149
213
KE1BG
NOMESCO Finland
MRI of prostate
10.5
48.7
101
79
N42.9
ICD-10 Finland
Disorder of prostate, unspecified
10.6
48.3
100
78
R30.0
ICD-10 Finland
Dysuria
5.5
47.1
151
230
A02BC05
ATC
esomeprazole; systemic
1.7
46.1
1443
8107
60500
ICD-8 Finland
Redundant prepuce and phimosis, Phimosis
+∞
46.1
48
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
6.9
46.0
123
148
J01MA12
ATC
levofloxacin; systemic
2.0
44.8
650
2817
Y06
ICPC
Prostate symptom/complaint
5.4
44.1
143
221
KFD20
NOMESCO Finland
Excision of hydrocele of testis
382.0
43.5
47
*
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
3.6
43.3
212
492
N43.3
ICD-10 Finland
Hydrocele, unspecified
15.8
43.3
75
39
SPAT1167
SPAT
Insertion of urinary catheter
7.4
42.4
108
121
TKC20
NOMESCO Finland
Catheterisation of bladder
3.1
41.5
251
684
Y85
ICPC
Benign prostatic hypertrophy
12.8
41.4
78
50
KE1CG
NOMESCO Finland
Extensive MRI of prostate
10.8
40.7
83
63
N32.82
ICD-10 Finland
Instability of the detrusor vesicae muscle
11.5
40.5
80
57
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.9
39.9
755
3598
SPAT1263
SPAT
Sampling
1.7
39.4
1202
6633
A02BC02
ATC
pantoprazole; systemic
1.6
38.6
2259
14654
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
38.0
965
5043
KDV10
NOMESCO Finland
Internal urethrotomy
19.6
37.5
60
25
XKW99
NOMESCO Finland
Other physiological examination of urinary or male genital system
14.4
37.5
67
38
G04BD11
ATC
fesoterodine; oral
8.3
37.4
88
87
N46
ICD-10 Finland
Male infertility
324.1
36.8
40
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
36.6
977
5169
KED76
NOMESCO Finland
TUVP
167.0
36.5
41
*
N48.4
ICD-10 Finland
Impotence of organic origin
4.4
36.3
141
266
KEB00
NOMESCO Finland
Biopsy of prostate
11.2
35.1
70
51
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
34.7
590
2693
G47.3
ICD-10 Finland
Sleep apnoea
1.6
34.4
1212
6892
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
33.5
842
4363
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
2.1
32.8
420
1717
UJF32
NOMESCO Finland
Coloscopy
1.7
32.7
739
3701
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
32.2
414
1694
U01
ICPC
Dysuria/painful urination
6.0
31.9
93
127
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
31.9
713
3561
U13
ICPC
Bladder symptom/complaint other
8.7
31.6
72
68
ZXC96
NOMESCO Finland
Robot assisted procedure
3.5
31.3
157
372
N48.1
ICD-10 Finland
Balanoposthitis
4.2
31.0
124
241
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
30.0
910
4946
N03AX16
ATC
pregabalin; oral
1.7
29.8
797
4182
J01CA08
ATC
pivmecillinam; oral
3.5
28.4
140
328
N30.9
ICD-10 Finland
Cystitis, unspecified
5.8
28.1
84
119
A02BC01
ATC
omeprazole; systemic
1.6
27.6
784
4173
N43.0
ICD-10 Finland
Encysted hydrocele
86.7
27.0
32
*
N35.9
ICD-10 Finland
Urethral stricture, unspecified
6.8
26.9
71
85
N48.6
ICD-10 Finland
Induratio penis plastica
30.1
26.3
37
10
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
26.1
1012
5812
R06.0
ICD-10 Finland
Dyspnoea
1.7
26.1
653
3352
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
12.5
26.0
49
32
M54.5
ICD-10 Finland
Low back pain
1.5
25.9
1109
6514
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.0
25.8
348
1447
N06AX21
ATC
duloxetine; oral
2.0
25.8
354
1482
N02AX02
ATC
tramadol; systemic, rectal
1.4
25.3
1591
10112
N03AX12
ATC
gabapentin; oral
1.8
25.1
511
2462
A02BC03
ATC
lansoprazole; oral
1.6
24.7
895
5052
KFD30
NOMESCO Finland
Operation for spermatocele
113.7
24.3
28
*
J01CA04
ATC
amoxicillin; systemic
1.4
24.1
2821
20070
G04BD07
ATC
tolterodine; oral
4.2
24.1
96
187
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.4
23.9
1401
8756
J01DB01
ATC
cefalexin; oral
1.5
23.4
3061
22178
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
23.3
704
3792
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
23.0
2225
15217
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
22.2
1321
8249
N06AX11
ATC
mirtazapine; oral
1.5
22.1
1010
5981
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
22.0
1178
7201
U29
ICPC
Urinary symptom/complaint other
5.5
21.9
68
102
L03
ICPC
Low back symptom/complaint
1.6
21.8
611
3222
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.8
21.7
444
2139
SPAT1153
SPAT
Removal of sutures
1.5
21.5
904
5252
Z03.1
ICD-10 Finland
Observation for suspected malignant neoplasm
5.0
21.1
71
117
K40.9
ICD-10 Finland
Unilateral or unspecified inguinal hernia, without obstruction or gangrene
1.6
20.9
569
2973
A02BA02
ATC
ranitidine; systemic
1.6
20.9
545
2816
KCW02
NOMESCO Finland
Lavation of bladder for coagulated blood
12.2
20.7
39
26
NK6AN
NOMESCO Finland
Total body bone isotope imaging
4.4
20.6
77
142
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
20.4
749
4215
M01AE02
ATC
naproxen; oral, rectal
1.4
20.2
1951
13203
KCE02
NOMESCO Finland
Transluminal endoscopic extraction of calculus from bladder
15.0
20.2
35
19
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
20.2
246
982
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
20.1
482
2431
N06AA09
ATC
amitriptyline; systemic
2.0
19.9
261
1073
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
19.8
1744
11607
WX704
NOMESCO Finland
Intubation
2.1
19.7
250
1012
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
7.3
19.6
49
55
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
19.5
305
1341
J01MA01
ATC
ofloxacin; systemic
2.0
19.4
255
1050
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
19.2
828
4818
M03BX02
ATC
tizanidine; oral
1.4
19.1
2483
17568
SPAT1301
SPAT
No procedures
1.5
19.1
748
4264
C05AA08
ATC
fluocortolone; rectal, topical
1.7
19.0
484
2480
M79.6
ICD-10 Finland
Pain in limb
1.4
19.0
991
5998
J01MA06
ATC
norfloxacin; oral
2.0
19.0
257
1069
M01AH05
ATC
etoricoxib; oral
1.4
18.9
2384
16766
Z01.2
ICD-10 Finland
Dental examination
1.4
18.9
1299
8267
J01AA02
ATC
doxycycline; systemic
1.4
18.8
2843
20595
R51.80
ICD-10 Finland
Headache
1.8
18.7
360
1697
WX402
NOMESCO Finland
General anaesthesia
1.6
18.6
600
3266
J02AC01
ATC
fluconazole; systemic
1.5
18.3
648
3606
P03
ICPC
Feeling depressed
2.1
18.2
218
862
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
18.2
1015
6210
N30
ICD-10 Finland
Cystitis
4.4
18.2
68
126
D40.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Prostate
4.7
18.0
63
109
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
17.9
404
1998
SAA01
NOMESCO Finland
Simple examination of mouth
1.4
17.8
2595
18588
KDV12
NOMESCO Finland
Urethroscopic internal urethrotomy
6.8
17.7
46
55
SPAT1043
SPAT
Audiometry
2.2
17.7
180
664
N32.83
ICD-10 Finland
Nozzle synergy in the bladder neck
11.5
17.7
34
24
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
17.6
255
1090
H13
ICPC
Plugged feeling ear
1.7
17.5
424
2139
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.3
17.5
1698
11400
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
17.4
287
1285
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
17.4
1755
11855
WZC30
NOMESCO Finland
Teaching
1.7
17.3
433
2206
6050A
ICD-9 Finland
Redundant prepuce and phimosis[PHIMOSIS]
+∞
17.2
18
*
KDE20
NOMESCO Finland
Removal of foreign body from urethra
5.0
17.2
57
93
R42
ICD-10 Finland
Dizziness and giddiness
1.6
17.2
456
2359
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
17.2
282
1262
R05
ICD-10 Finland
Cough
1.6
17.0
461
2399
8148/2-C61.9
ICD-O-3
Glandular intraepithelial neoplasia, high grade of prostate gland
21.1
17.0
26
10
R30.1
ICD-10 Finland
Vesical tenesmus
5.0
16.8
56
92
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
16.8
855
5130
R01AD09
ATC
mometasone; nasal
1.4
16.7
1397
9144
N41.8
ICD-10 Finland
Other inflammatory diseases of prostate
10.7
16.6
33
25
SPAT1240
SPAT
Therapeutic discussion
1.8
16.6
288
1312
N04BC05
ATC
pramipexole; oral
2.2
16.5
178
674
JN2CG
NOMESCO Finland
Extensive MRI examination of lower part of abdoment with high intensity magnet
3.9
16.5
69
143
N39.4
ICD-10 Finland
Other specified urinary incontinence
4.3
16.2
62
118
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.8
16.1
271
1219
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
16.0
655
3757
N06AX16
ATC
venlafaxine; oral
1.6
15.9
420
2170
R06.5
ICD-10 Finland
Mouth breathing
1.6
15.9
447
2347
N21.0
ICD-10 Finland
Calculus in bladder
6.7
15.7
41
50
Z3231
NOMESCO Finland
Registered nurse
1.4
15.6
794
4752
R01AD12
ATC
fluticasone furoate; nasal
1.4
15.6
890
5444
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
15.5
1858
12792
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
15.5
301
1424
G44.2
ICD-10 Finland
Tension-type headache
1.8
15.5
283
1311
C07AA05
ATC
propranolol; systemic
1.5
15.4
515
2821
N05CF01
ATC
zopiclone; oral
1.4
15.4
870
5312
7542
FHL
Circumcisio
40.5
15.3
20
*
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.4
15.3
1217
7872
N05BA04
ATC
oxazepam; oral
1.5
15.3
610
3476
P01AB01
ATC
metronidazole; oral, rectal
1.4
15.2
1015
6375
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.5
15.2
700
4108
N06AB10
ATC
escitalopram; oral
1.5
15.2
578
3259
U70
ICPC
Pyelonephritis/pyelitis
8.1
14.8
34
34
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.9
14.8
232
1019
L17
ICPC
Foot/toe symptom/complaint
1.5
14.8
547
3063
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.7
14.8
355
1788
S18
ICPC
Laceration/cut
1.3
14.7
1217
7910
R05
ICPC
Cough
1.6
14.7
467
2528
M01AB05
ATC
diclofenac; systemic, rectal
1.3
14.7
2637
19160
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
14.6
1624
11030
L08
ICPC
Shoulder symptom/complaint
1.5
14.6
532
2970
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
14.5
904
5607
R02
ICPC
Shortness of breath/dyspnoea
1.8
14.5
246
1112
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
14.4
427
2271
I10
ICD-10 Finland
Essential (primary) hypertension
1.3
14.4
1838
12723
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
14.3
457
2472
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
14.3
1317
8691
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
3.3
14.3
74
184
SPAT1312
SPAT
General health counselling
1.4
14.2
737
4420
Y73
ICPC
Prostatitis/seminal vesiculitis
11.5
14.2
27
19
R01AD08
ATC
fluticasone; nasal
1.4
14.2
845
5200
AA1AD
NOMESCO Finland
CT of head and brain
1.4
14.1
655
3845
N05AH04
ATC
quetiapine; oral
1.5
14.0
531
2988
SPAT1325
SPAT
Vaccination
1.5
13.8
569
3259
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
13.8
489
2712
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
13.7
174
706
N41
ICD-10 Finland
Inflammatory diseases of prostate
4.4
13.7
51
95
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.6
13.7
382
1999
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
13.7
525
2962
ZXE10
NOMESCO Finland
More than one and less than three hours
1.3
13.6
1043
6682
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
13.6
646
3807
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
13.5
1224
8040
WX290
NOMESCO Finland
Other blockade of nerve
1.3
13.4
1665
11437
SDA02
NOMESCO Finland
Parodonthologic therapy
1.4
13.4
940
5932
K59.09
ICD-10 Finland
Constipation, unspecified
2.5
13.4
110
364
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.7
13.4
263
1249
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
13.4
1196
7842
L01
ICPC
Neck symptom/complaint
1.7
13.3
283
1376
SPAT1097
SPAT
Recording of ECG
1.6
13.3
349
1798
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
13.3
581
3367
U06
ICPC
Haematuria
3.8
13.2
57
123
TKD00
NOMESCO Finland
Dilatation of urethra
10.5
13.1
26
20
JN3AD
NOMESCO Finland
Abdominal CT examination
1.8
13.1
245
1142
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
13.1
321
1625
R13
ICD-10 Finland
Dysphagia
2.1
13.1
154
607
SPAT1310
SPAT
Counselling related to known health issue
1.4
13.1
756
4620
K30
ICD-10 Finland
Functional dyspepsia
1.8
13.0
234
1081
N02AJ06
ATC
codeine and paracetamol; systemic
1.3
13.0
1401
9425
KH1AD
NOMESCO Finland
CT of urinary organs
2.2
13.0
140
532
D01
ICPC
Abdominal pain/cramps general
1.9
13.0
202
887
R06AE07
ATC
cetirizine; oral
1.3
12.8
1156
7581
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
12.8
543
3126
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.6
12.8
358
1877
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
12.7
3563
27317
U71
ICPC
Cystitis/urinary infection other
5.5
12.7
38
56
D06
ICPC
Abdominal pain localized other
2.1
12.7
142
547
R07.3
ICD-10 Finland
Other chest pain
1.7
12.7
257
1232
KE1AE
NOMESCO Finland
Percutaneous utlrasound examination fo prostata
9.1
12.7
27
24
R53
ICD-10 Finland
Malaise and fatigue
1.5
12.7
424
2320
KCV04
NOMESCO Finland
Distension of bladder with fluid
11.4
12.6
24
17
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
12.6
289
1436
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.0
12.6
172
721
N06AB04
ATC
citalopram; systemic
1.4
12.6
563
3276
N17
ICPC
Vertigo/dizziness
2.0
12.6
172
722
J01DA01
ATC
[U] cefalexin; systemic
1.3
12.6
2043
14493
A06AD11
ATC
lactulose; oral
1.7
12.6
272
1328
JAB30
NOMESCO Finland
Repair of inguinal hernia using prosthetic material
1.5
12.5
416
2271
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
12.5
283
1402
N43.2
ICD-10 Finland
Other hydrocele
43.2
12.5
16
*
L15
ICPC
Knee symptom/complaint
1.5
12.5
465
2606
ZXE00
NOMESCO Finland
One hour or less
1.3
12.4
1101
7196
WX110
NOMESCO Finland
Local anesthesy
1.3
12.4
2432
17655
H04.10
ICD-10 Finland
Dry eye syndrome
1.8
12.4
205
921
-1
NOMESCO Finland
NA
1.3
12.3
1054
6849
G04BD04
ATC
oxybutynin; oral, transdermal
3.2
12.3
65
165
WX725
NOMESCO Finland
Noninvasive ventilation
2.0
12.3
153
619
N06AX12
ATC
bupropion; oral
1.8
12.2
211
962
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
12.2
230
1077
116
Kela drug reimbursment
Prostate cancer
2.4
12.2
103
349
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.7
12.1
258
1253
308
Kela drug reimbursment
Alprostadil, sildenafil and combination product containing aviptadil and phentolamine
3.1
12.1
68
178
A02BC04
ATC
rabeprazole; oral
1.7
12.1
246
1179
SPAT1262
SPAT
Handing over of treatment supplies
1.4
12.0
556
3255
N31.1
ICD-10 Finland
Reflex neuropathic bladder, not elsewhere classified
7.0
12.0
30
35
R52.9
ICD-10 Finland
Pain, unspecified
1.8
12.0
196
878
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.4
11.9
546
3190
D29.1
ICD-10 Finland
Benign neoplasm: Prostate
9.2
11.9
25
22
KA1AE
NOMESCO Finland
Kidney ultrasound examination
2.7
11.8
81
243
KCH42
NOMESCO Finland
Transurethral incision or resection of bladder neck
32.4
11.8
16
*
M02AA07
ATC
piroxicam; topical
1.3
11.8
1090
7152
J01FF01
ATC
clindamycin; systemic
1.3
11.7
895
5710
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
11.7
490
2814
N06AB06
ATC
sertraline; oral
1.6
11.7
297
1517
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
11.7
727
4487
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
1.7
11.7
252
1231
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.0
11.6
154
639
M01AC06
ATC
meloxicam; systemic, rectal
1.3
11.6
1141
7553
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.8
11.6
219
1027
R00.2
ICD-10 Finland
Palpitations
2.0
11.5
141
567
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
11.5
155
646
R10.2
ICD-10 Finland
Pelvic and perineal pain
3.3
11.5
58
143
M25.5
ICD-10 Finland
Pain in joint
1.3
11.4
814
5133
KF8KT
NOMESCO Finland
Sclerotherapy of scrotum
56.7
11.4
14
*
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.4
11.4
643
3902
SDA04
NOMESCO Finland
Very demanding parodonthologic therapy
1.3
11.4
811
5115
N05BA01
ATC
diazepam; systemic, rectal
1.5
11.3
380
2080
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
11.3
415
2314
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.8
11.3
206
954
A07AA02
ATC
nystatin; oral
2.2
11.2
115
429
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.0
11.2
146
601
B01AB05
ATC
enoxaparin; parenteral
1.3
11.2
788
4961
K03.64
ICD-10 Finland
Dental calculus supragingival
1.3
11.1
783
4928
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
11.1
192
878
SPAT1260
SPAT
Consultation of another employee
1.5
11.1
391
2165
WX002
NOMESCO Finland
Sedation and analgesia
1.4
11.1
510
2983
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
11.1
1717
12036
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
11.0
508
2967
R03AC02
ATC
salbutamol; inhalant
1.3
11.0
1532
10597
N50.8
ICD-10 Finland
Other specified disorders of male genital organs
8.5
10.9
24
23
D07AC01
ATC
betamethasone; topical
1.3
10.9
1018
6680
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
10.9
2019
14448
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
2.8
10.8
69
200
Z01.9
ICD-10 Finland
Special examination, unspecified
2.0
10.8
139
571
N42.8
ICD-10 Finland
Other specified disorders of prostate
7.3
10.8
26
29
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
10.7
2126
15319
H29
ICPC
Ear symptom/complaint other
1.8
10.7
192
889
M48.0
ICD-10 Finland
Spinal stenosis
1.6
10.7
279
1439
A03FA02
ATC
cisapride; oral, rectal
2.0
10.7
142
590
UKC05
NOMESCO Finland
Cystoscopy and bladder biopsy
4.7
10.6
36
62
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.5
10.6
363
1993
60798
ICD-8 Finland
Other disease of male genital organs, Alii definiti
+∞
10.5
11
*
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.5
10.5
324
1737
K02.1
ICD-10 Finland
Caries of dentine
1.2
10.5
2037
14625
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.7
10.5
206
981
G04BD09
ATC
trospium; oral
4.5
10.4
37
67
Y05
ICPC
Scrotum/testis sympt/compl other
4.5
10.4
37
67
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.5
10.4
428
2447
A04
ICPC
Weakness/tiredness general
1.8
10.4
191
892
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.8
10.3
180
824
XF402
NOMESCO Finland
ECG with work load test
1.5
10.3
328
1772
R93.4
ICD-10 Finland
Abnormal findings on diagnostic imaging of urinary organs
6.4
10.3
27
34
SPAT1254
SPAT
Administration of medicine
1.6
10.3
292
1535
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.4
10.3
590
3587
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
10.3
250
1264
C07AB02
ATC
metoprolol; systemic
1.5
10.3
370
2055
N45.0
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis with abscess
18.5
10.3
16
7
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
2.7
10.2
71
215
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
9.9
823
5300
M54.1
ICD-10 Finland
Radiculopathy
2.0
9.9
128
527
D11
ICPC
Diarrhoea
1.6
9.9
236
1187
N05CF02
ATC
zolpidem; oral
1.4
9.9
508
3030
R50.9
ICD-10 Finland
Fever, unspecified
1.5
9.8
359
1999
SPAT1104
SPAT
Monitoring of emergency patient
1.8
9.8
163
736
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
9.8
159
711
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
2.5
9.8
77
253
Z71.8
ICD-10 Finland
Other specified counselling
1.4
9.7
588
3605
N12
ICD-10 Finland
Tubulo-interstitial nephritis, not specified as acute or chronic
4.5
9.7
34
61
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.5
9.7
303
1632
R05FB02
ATC
cough suppressants and expectorants
1.3
9.7
1007
6687
G04BE01
ATC
alprostadil; parenteral, urethral
3.0
9.7
56
153
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.6
9.7
262
1362
SPAT1168
SPAT
Catheterisation training
8.5
9.7
21
20
M43.1
ICD-10 Finland
Spondylolisthesis
2.1
9.6
111
437
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.3
9.6
646
4026
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.1
9.6
104
399
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.6
9.5
231
1165
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.4
9.5
546
3318
Z00.0
ICD-10 Finland
General medical examination
1.4
9.4
436
2549
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
9.4
294
1583
R03DC03
ATC
montelukast; oral
1.5
9.4
379
2155
P20
ICPC
Memory disturbance
2.1
9.4
105
408
A03CA02
ATC
clidinium and psycholeptics; oral
2.0
9.4
118
481
N03AE01
ATC
clonazepam; systemic
1.8
9.4
166
765
KCV12
NOMESCO Finland
Urinary bladder endoscopic botulin therapy
9.6
9.4
19
16
D82
ICPC
Teeth/gum disease
1.3
9.3
1043
6984
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
1.7
9.3
180
853
N48.8
ICD-10 Finland
Other specified disorders of penis
7.4
9.3
22
24
M01AX05
ATC
glucosamine; oral
1.5
9.3
329
1821
JN4AD
NOMESCO Finland
Body CT examination
1.7
9.3
206
1015
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.5
9.3
72
234
H02AB06
ATC
prednisolone; systemic
1.2
9.2
1354
9368
KMAK
NOMESCO Finland
NA
1.2
9.2
1776
12670
J01FA09
ATC
clarithromycin; systemic
1.3
9.2
974
6479
R96
ICPC
Asthma
1.8
9.1
155
705
N01
ICPC
Headache
1.8
9.1
151
682
TKC10
NOMESCO Finland
Percutaneous puncture of bladder
6.3
9.1
24
31
N45
ICD-10 Finland
Orchitis and epididymitis
6.3
9.1
24
31
R5140
NOMESCO Finland
Monitoring the use of the aid
1.4
9.1
471
2810
B02AA02
ATC
tranexamic acid; systemic
2.1
9.1
98
376
N05CD07
ATC
temazepam; oral
1.5
9.1
278
1489
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
1.6
9.1
212
1061
A01
ICPC
Pain general/multiple sites
1.8
9.1
145
647
R12
ICD-10 Finland
Heartburn
1.8
9.0
163
758
UDC00
NOMESCO Finland
Ear microscopy
1.7
9.0
190
924
TKF60
NOMESCO Finland
Puncture of scrotum
32.3
9.0
12
*
Y77
ICPC
Malignant neoplasm prostate
2.8
8.9
56
161
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.0
8.9
108
434
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.6
8.9
236
1221
M54.6
ICD-10 Finland
Pain in thoracic spine
1.7
8.9
178
853
K03.80
ICD-10 Finland
Irradiated enamel
2.0
8.9
114
467
S22
ICPC
Nail symptom/complaint
2.0
8.9
118
491
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.7
8.9
172
816
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
1.4
8.9
465
2780
H02AB04
ATC
methylprednisolone; systemic
1.4
8.8
369
2115
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.6
8.8
208
1043
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.4
8.8
446
2649
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
3.0
8.8
51
140
J31.0
ICD-10 Finland
Chronic rhinitis
1.6
8.8
216
1097
D01BA02
ATC
terbinafine; oral; topical
1.3
8.8
994
6658
SCA01
NOMESCO Finland
Simple analysis and advice of nutrition with regard to dentistry
1.3
8.8
690
4400
G04BE03
ATC
sildenafil; oral
2.8
8.8
55
158
R32
ICD-10 Finland
Unspecified urinary incontinence
4.9
8.8
28
46
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.5
8.8
273
1469
UKD02
NOMESCO Finland
Urethroscopy
7.7
8.7
20
21
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
8.7
252
1333
N31.0
ICD-10 Finland
Uninhibited neuropathic bladder, not elsewhere classified
16.2
8.7
14
7
G04BE30
ATC
drugs used in erectile dysfunction - combinations
5.3
8.6
26
40
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.7
8.6
58
174
S29
ICPC
Skin symptom/complaint other
1.5
8.6
323
1811
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.2
8.6
85
314
A98
ICPC
Health maint/preventive medicine
1.4
8.6
3731
29132
L28
ICPC
Limited function/disability (L)
1.6
8.6
247
1305
E29.1
ICD-10 Finland
Testicular hypofunction
2.2
8.6
89
335
N05AA02
ATC
levomepromazine; systemic
1.7
8.5
162
764
TPH07
NOMESCO Finland
Cathetrisation of artery
1.5
8.5
285
1558
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.6
8.5
61
190
J01FA10
ATC
azithromycin; systemic
1.2
8.5
1845
13284
P06
ICPC
Sleep disturbance
1.5
8.5
260
1393
N50.9
ICD-10 Finland
Disorder of male genital organs, unspecified
6.4
8.5
22
28
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.7
8.5
180
877
D41.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bladder
3.2
8.4
44
113
H02
ICPC
Hearing complaint
1.7
8.4
175
849
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
1.9
8.4
128
563
N03AG01
ATC
valproic acid; systemic, rectal
1.7
8.4
189
939
J05AB01
ATC
aciclovir; systemic
1.4
8.3
425
2528
P25
ICPC
Phase of life problem adult
2.3
8.3
75
265
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.6
8.3
211
1082
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
1.5
8.3
284
1562
E0000UV
ATC
NA
1.3
8.3
965
6478
J34.2
ICD-10 Finland
Deviated nasal septum
1.5
8.3
285
1568
N41.3
ICD-10 Finland
Prostatocystitis
14.2
8.3
14
8
H81
ICPC
Excessive ear wax
1.4
8.3
364
2106
L04
ICPC
Chest symptom/complaint
1.9
8.3
117
499
M01AH02
ATC
rofecoxib; oral
1.5
8.2
299
1667
H03AA01
ATC
levothyroxine sodium; systemic
1.5
8.2
303
1692
R05FA02
ATC
opium derivatives and expectorants; systemic
1.3
8.2
1084
7387
F34.1
ICD-10 Finland
Dysthymia
2.1
8.2
96
381
VALMI
NOMESCO Finland
NA
1.3
8.2
674
4323
R39.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the urinary system
4.1
8.2
31
61
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
4.1
8.2
31
61
WZA90
NOMESCO Finland
Other doctors statement
1.3
8.2
658
4208
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
8.2
412
2447
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
1.9
8.1
122
532
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.6
8.1
201
1024
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.6
8.1
196
994
L82
ICD-10 Finland
Seborrhoeic keratosis
1.5
8.1
318
1803
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.1
488
2987
U04
ICPC
Incontinence urine
3.0
8.1
46
125
SPAT1255
SPAT
Intravenous administration of medicine
1.7
8.0
176
867
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
2.0
8.0
103
424
M79.1
ICD-10 Finland
Myalgia
1.5
8.0
273
1501
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.4
8.0
452
2740
R09
ICPC
Sinus symptom/complaint
1.9
8.0
115
497
H02.3
ICD-10 Finland
Blepharochalasis
2.1
7.9
88
344
SPAT1211
SPAT
Application of soft bandage
1.7
7.9
175
865
J02AC02
ATC
itraconazole; systemic
1.4
7.9
459
2791
K59.1
ICD-10 Finland
Functional diarrhoea
2.1
7.9
92
366
M01AX17
ATC
nimesulide; oral
1.3
7.9
679
4383
U99
ICPC
Urinary disease other
6.1
7.9
21
28
L02
ICPC
Back symptom/complaint
1.7
7.9
179
890
H01BA02
ATC
desmopressin; nasal, systemic, sublingual
3.6
7.9
35
80
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
1.9
7.9
106
446
N06AX26
ATC
vortioxetine; oral
1.7
7.8
154
736
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
7.8
792
5223
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
1.5
7.7
241
1298
N99.1
ICD-10 Finland
Postprocedural urethral stricture
8.1
7.7
17
17
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
3.2
7.7
40
103
ZXA10
NOMESCO Finland
Bilateral
1.4
7.7
366
2152
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
7.7
387
2297
H93.1
ICD-10 Finland
Tinnitus
1.6
7.7
198
1021
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
1.6
7.7
177
884
C02AC05
ATC
moxonidine; oral
1.8
7.7
131
598
60100
ICD-8 Finland
Prostatitis, Acuta
+∞
7.7
8
*
L02AE02
ATC
leuprorelin; implant, parenteral
2.5
7.6
59
193
M01AC01
ATC
piroxicam; systemic, rectal
1.4
7.6
394
2351
F29
ICPC
Eye symptom/complaint other
1.7
7.6
153
735
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
2.4
7.6
63
216
N49.2
ICD-10 Finland
Inflammatory disorders of scrotum
8.6
7.6
16
15
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
4.5
7.6
26
47
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.5
7.6
230
1234
XA800
NOMESCO Finland
Neuropsychological investigation
1.7
7.5
166
818
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
1.7
7.5
146
697
N30.1
ICD-10 Finland
Interstitial cystitis (chronic)
7.6
7.5
17
18
A28
ICPC
Limited function/disability NOS
1.6
7.5
194
999
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.3
7.4
671
4358
UJG02
NOMESCO Finland
Proctoscopy
2.4
7.4
61
207
N06AG02
ATC
moclobemide; oral
1.8
7.4
129
593
N31.8
ICD-10 Finland
Other neuromuscular dysfunction of bladder
9.3
7.4
15
13
SPAT1377
SPAT
Polysomnography
1.8
7.4
116
516
UDQ12
NOMESCO Finland
Flexible laryngoscopy
1.7
7.4
158
773
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
1.9
7.4
112
492
A11
ICPC
Chest pain NOS
1.7
7.4
163
806
ZXA05
NOMESCO Finland
Left side
1.3
7.4
653
4231
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.9
7.4
102
434
R21
ICPC
Throat symptom/complaint
1.4
7.3
330
1921
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
2.5
7.3
57
188
SPAT1161
SPAT
Ultrasound examination of urinary bladder
8.1
7.3
16
16
205
Kela drug reimbursment
Chronic hypertension
1.3
7.3
642
4157
WX240
NOMESCO Finland
Penis blockade
26.9
7.3
10
*
K40.2
ICD-10 Finland
Bilateral inguinal hernia, without obstruction or gangrene
2.0
7.2
95
397
M03BC51
ATC
orphenadrine, combinations; systemic
1.2
7.2
907
6134
R52.2
ICD-10 Finland
Other chronic pain
2.1
7.2
82
323
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
7.2
129
599
J01AA04
ATC
lymecycline; systemic
1.4
7.2
320
1857
K10.3
ICD-10 Finland
Alveolitis of jaws
1.7
7.2
134
630
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.8
7.2
125
574
SPAT1138
SPAT
Guidance concerning bowel function
4.4
7.2
25
46
SFA00
NOMESCO Finland
Small filling
1.4
7.1
388
2332
L90.0
ICD-10 Finland
Lichen sclerosus et atrophicus
4.1
7.1
27
54
KFD16
NOMESCO Finland
Partial excision of epididymis
17.8
7.1
11
5
D12.8
ICD-10 Finland
Benign neoplasm: Rectum
2.0
7.1
92
382
C10AA01
ATC
simvastatin; oral
1.2
7.1
1188
8285
C07AB07
ATC
bisoprolol; oral
1.2
7.1
1277
8974
D12
ICPC
Constipation
2.7
7.1
47
143
Z12.5
ICD-10 Finland
Special screening examination for neoplasm of prostate
3.4
7.1
33
79
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.7
7.0
138
660
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
1.8
7.0
113
509
F51.0
ICD-10 Finland
Nonorganic insomnia
1.4
7.0
300
1730
S04
ICPC
Lump/swelling localized
1.6
7.0
169
857
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.8
7.0
111
497
SPAT1216
SPAT
Assessment of functional ability
1.5
7.0
222
1203
H60.9
ICD-10 Finland
Otitis externa, unspecified
1.6
7.0
178
915
M02AA10
ATC
ketoprofen; topical
1.4
7.0
423
2592
TKC50
NOMESCO Finland
Training of urinary bladder
36.3
7.0
9
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
1.7
6.9
145
706
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
6.9
960
6564
N02AA05
ATC
oxycodone; systemic
1.4
6.9
313
1824
J01FA06
ATC
roxithromycin; oral
1.2
6.9
1166
8140
R07.0
ICD-10 Finland
Pain in throat
1.8
6.9
117
537
M03BX01
ATC
baclofen; systemic
2.5
6.8
51
165
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
1.8
6.8
104
461
J05AB11
ATC
valaciclovir; oral
1.5
6.8
267
1514
F41.09
ICD-10 Finland
UNS Panic Syndrome
2.3
6.8
62
221
D17.1
ICD-10 Finland
Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
1.9
6.8
94
402
D23.5
ICD-10 Finland
Benign neoplasm: Skin of trunk
2.4
6.8
54
181
R29
ICPC
Respiratory symptom/complaint other
1.7
6.8
139
675
J01AA07
ATC
tetracycline; systemic
1.4
6.8
318
1865
K61.1
ICD-10 Finland
Rectal abscess
4.7
6.8
22
38
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.4
6.7
315
1845
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
2.7
6.7
43
127
XKG00
NOMESCO Finland
Artificial induction of erection
8.7
6.7
14
13
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.5
6.7
204
1095
KGH96
NOMESCO Finland
Other reconstructive operation on penis
+∞
6.7
7
*
Z94.0
ICD-10 Finland
Kidney transplant status
2.5
6.7
50
162
DJD20
NOMESCO Finland
Plastic repair of septum of nose
1.5
6.7
208
1122
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
2.7
6.7
44
134
N05BA12
ATC
alprazolam; oral
1.5
6.6
262
1487
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
1.5
6.6
191
1011
L13
ICPC
Hip symptom/complaint
1.5
6.6
219
1197
N06AX03
ATC
mianserin; oral
1.7
6.6
122
574
F45.8
ICD-10 Finland
Other somatoform disorders
1.7
6.6
122
574
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.6
6.6
171
885
M77.1
ICD-10 Finland
Lateral epicondylitis
1.4
6.6
271
1553
ZXD05
NOMESCO Finland
Urgent procedure
1.2
6.6
833
5630
M54.3
ICD-10 Finland
Sciatica
1.6
6.6
161
820
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
6.5
145
720
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
6.5
73
288
A06AC51
ATC
ispaghula, combinations; systemic
1.9
6.5
94
409
SPAT1307
SPAT
Psychosocial counselling and guidance
1.8
6.5
101
448
JAB11
NOMESCO Finland
Laparoscopic repair of inguinal hernia
1.9
6.5
89
379
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.4
6.5
261
1489
L04AD01
ATC
ciclosporin; systemic
2.1
6.4
70
273
A01AB09
ATC
miconazole; local oral
1.7
6.4
142
703
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.6
6.4
144
718
I86.1
ICD-10 Finland
Scrotal varices
2.8
6.4
41
121
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.0
6.4
78
316
WX720
NOMESCO Finland
Own respiration
1.7
6.4
120
567
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
6.4
1578
11395
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
2.0
6.4
80
330
KC1AE
NOMESCO Finland
Percutaneous ultrasound examination of urinary bladder
16.2
6.3
10
5
TAB00
NOMESCO Finland
Lumbar puncture
1.7
6.3
121
576
S09
ICPC
Infected finger/toe
2.1
6.3
67
259
M47.9
ICD-10 Finland
Spondylosis, unspecified
1.9
6.3
84
355
E66.8
ICD-10 Finland
Other obesity
1.7
6.3
136
671
L04AA06
ATC
mycophenolic acid; systemic
2.0
6.3
73
292
ZXE20
NOMESCO Finland
More than three and less than five hours
1.4
6.3
361
2193
KD1GB
NOMESCO Finland
Uretrocystogpaphy with X-ray
4.8
6.3
20
34
A02BD07
ATC
lansoprazole, amoxicillin and clarithromycin; systemic
1.7
6.3
117
552
SPAT1229
SPAT
Assessment of need for aid
1.7
6.3
115
539
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.4
6.3
268
1545
S82
ICPC
Naevus/mole
1.5
6.3
196
1061
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
1.6
6.3
158
812
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.5
6.3
190
1021
N86
ICPC
Multiple sclerosis
5.7
6.2
17
24
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
1.5
6.2
197
1067
R03BA05
ATC
fluticasone; inhalant
1.3
6.2
401
2479
KH1AE
SPAT
NA
2.3
6.2
53
184
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.5
6.2
179
949
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.5
6.2
194
1049
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.4
6.2
266
1534
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.4
6.2
309
1833
SPAT1058
SPAT
PEF monitoring instruction
1.6
6.2
151
769
R55
ICD-10 Finland
Syncope and collapse
1.5
6.2
217
1204
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
4.0
6.2
23
46
NF1AA
NOMESCO Finland
Hip X-ray examination
1.6
6.2
149
757
L90
ICPC
Osteoarthrosis of knee
1.8
6.1
107
495
N06AA12
ATC
doxepin; systemic
1.7
6.1
124
601
SPAT1170
SPAT
Uroflowmetry
32.3
6.1
8
*
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.4
6.1
259
1493
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.5
6.1
214
1186
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
3.5
6.1
27
63
Z2445
NOMESCO Finland
Psychologist
1.8
6.1
105
486
R01BA52
ATC
pseudoephedrine, combinations; oral
1.2
6.1
900
6184
J01.9
ICD-10 Finland
Acute sinusitis, unspecified
2.2
6.1
58
215
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.4
6.1
287
1689
C08CA02
ATC
felodipine; oral
1.6
6.1
168
883
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.6
6.1
132
654
L05
ICPC
Flank/axilla symptom/complaint
1.7
6.1
115
547
K59.0
ICD-10 Finland
Constipation
2.0
6.0
71
286
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
2.0
6.0
71
286
R11
ICD-10 Finland
Nausea and vomiting
1.7
6.0
123
596
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
1.5
6.0
187
1009
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.4
6.0
262
1518
A05
ICPC
Feeling ill
1.8
6.0
91
402

Mortality – FinRegistry

Association

Association between endpoint N14_PROSTHYPERPLA and mortality.

Females

No data

Males

Parameter HR [95% CI] p-value
N14_PROSTHYPERPLA 1.144 [1.06, 1.23] < 0.001
Birth year 0.986 [0.98, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 76532 out of 209249 males with N14_PROSTHYPERPLA died.

Mortality risk

Mortality risk for people of age

years, who have N14_PROSTHYPERPLA.

N-year risk Females Males
1 No data 0.175%
5 No data 1.063%
10 No data 2.672%
15 No data 4.985%
20 No data 8.298%

Relationships between endpoints

Index endpoint: N14_PROSTHYPERPLA – Hyperplasia of prostate

GWS hits: 68

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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