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Other and unspecified disorders of adult personality and behaviour

DOID EFO Endpoint Browser PheWeb

F5_PERSOTH

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — F68, F69
  • Cause of death: ICD-10 — F68, F69

2 out of 7 registries used, show all original rules.

223

4. Check minimum number of events

None

223

5. Include endpoints

None

223

6. Filter based on genotype QC (FinnGen only)

216

Control definitions (FinnGen only)

Control exclude
F5_PERSOBEH

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2012 998 1001
Only index persons 1845 947 898
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 30.95 30.95 30.80
Only index persons 29.81 29.99 29.62

-FinnGen-

Key figures

All Female Male
Number of individuals 216 146 70
Unadjusted period prevalence (%) 0.05 0.05 0.03
Median age at first event (years) 34.36 32.71 37.80

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
223
Matched controls
2230
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F69
ICD-10 Finland
Unspecified disorder of adult personality and behaviour
+∞
145.2
123
*
T36
ICD-10 Finland
Poisoning by systemic antibiotics
31.5
106.3
76
36
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
39.5
103.1
67
24
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
18.3
85.3
80
66
N05AH04
ATC
quetiapine; oral
11.4
77.0
131
248
N05AH03
ATC
olanzapine; systemic
15.6
75.1
77
73
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
14.3
73.0
80
84
N03AG01
ATC
valproic acid; systemic, rectal
15.5
67.2
67
60
N03AX09
ATC
lamotrigine; oral
17.1
66.9
62
49
F32.9
ICD-10 Finland
Depressive episode, unspecified
10.0
65.6
107
188
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
16.4
64.3
61
50
N05AA02
ATC
levomepromazine; systemic
19.9
59.9
50
32
F29
ICD-10 Finland
Unspecified nonorganic psychosis
15.9
56.8
54
44
N05AX08
ATC
risperidone; systemic
13.4
56.6
61
61
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
9.3
55.2
87
144
N05AX12
ATC
aripiprazole; systemic
14.8
54.6
54
47
N05AB03
ATC
perphenazine; systemic, rectal
21.6
52.0
41
23
N05BA01
ATC
diazepam; systemic, rectal
8.5
48.6
81
141
N06AX16
ATC
venlafaxine; oral
7.5
47.6
95
200
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
555.6
47.1
45
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
11.1
46.9
57
67
N03AE01
ATC
clonazepam; systemic
14.6
46.0
45
38
F68.8
ICD-10 Finland
Other specified disorders of adult personality and behaviour
+∞
45.4
42
*
F68.1
ICD-10 Finland
Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
+∞
45.4
42
*
F61.0
ICD-10 Finland
Mixed personality disorders
+∞
45.4
42
*
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
20.3
44.6
36
21
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
7.2
43.9
89
189
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
12.2
43.4
48
49
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
465.1
40.4
39
*
F60.9
ICD-10 Finland
Personality disorder, unspecified
465.1
40.4
39
*
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
9.5
38.7
52
69
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
7.6
38.3
66
117
N06AX11
ATC
mirtazapine; oral
5.8
37.7
138
489
N06AB04
ATC
citalopram; systemic
6.0
36.6
91
230
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
16.1
35.5
32
23
P99
ICPC
Psychological disorders other
13.7
35.1
35
30
N06AB06
ATC
sertraline; oral
6.3
35.0
76
169
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
13.7
34.2
34
29
F99
ICD-10 Finland
Mental disorder, not otherwise specified
14.2
33.1
32
26
N06AB03
ATC
fluoxetine; oral
6.4
32.7
68
144
N07BB01
ATC
disulfiram; oral
10.5
32.6
39
44
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
5.9
32.6
77
184
N06AX03
ATC
mianserin; oral
12.0
32.4
35
34
N03AX16
ATC
[U] pregabalin
5.3
31.4
89
248
P29
ICPC
Psychological sympt/compl other
6.6
31.3
60
117
ZY010
NOMESCO Finland
Hospital outpatient
8.8
30.8
43
59
N05BA04
ATC
oxazepam; oral
4.9
30.6
108
359
N06AX12
ATC
bupropion; oral
6.7
30.3
57
109
N05CF01
ATC
zopiclone; oral
4.8
29.8
108
365
N05CD07
ATC
temazepam; oral
8.0
29.7
45
68
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
39.8
27.4
34
10
N05BE01
ATC
buspirone; oral
11.4
27.1
30
30
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
10.0
27.0
33
38
F68.0
ICD-10 Finland
Elaboration of physical symptoms for psychological reasons
+∞
25.5
24
*
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
102.0
25.3
27
*
N03AF02
ATC
oxcarbazepine; oral
10.9
24.6
28
29
N06AB05
ATC
paroxetine; oral
7.9
24.6
37
55
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
10.3
24.4
29
32
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
7.6
24.3
38
59
N05AF03
ATC
chlorprothixene; systemic
23.3
23.9
34
17
N05BA06
ATC
lorazepam; systemic, sublingual
8.8
23.1
31
40
P76
ICPC
Depressive disorder
5.8
23.0
48
100
IGY02
NOMESCO Finland
Psychiatric monitoring contact
9.9
22.9
28
32
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
6.6
22.5
40
71
Z2446
NOMESCO Finland
Social worker
6.4
20.9
38
69
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
8.2
20.4
29
40
R56.8
ICD-10 Finland
Other and unspecified convulsions
7.3
19.8
31
48
P01
ICPC
Feeling anxious/nervous/tense
3.9
19.7
77
263
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.9
19.6
39
77
F34.1
ICD-10 Finland
Dysthymia
8.1
19.5
28
39
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
4.0
18.9
70
230
AA1AD
NOMESCO Finland
CT of head and brain
3.9
18.9
73
247
F60.8
ICD-10 Finland
Other specific personality disorders
206.7
18.8
19
*
N06AB10
ATC
escitalopram; oral
3.6
18.8
95
384
A06AD11
ATC
lactulose; oral
5.3
18.4
42
94
N05AD01
ATC
haloperidol; systemic
20.3
18.3
27
15
P03
ICPC
Feeling depressed
4.1
18.0
60
182
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
20.8
17.8
26
14
P80
ICPC
Personality disorder
194.8
17.8
18
*
C07AA05
ATC
propranolol; systemic
3.5
17.6
87
344
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
7.1
17.6
28
44
J45.9
ICD-10 Finland
Asthma, unspecified
3.9
17.2
63
204
F31.8
ICD-10 Finland
Other bipolar affective disorders
16.9
17.2
27
18
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
6.5
17.2
30
52
N06AX21
ATC
duloxetine; oral
4.2
17.1
54
157
N03AX12
ATC
[U] gabapentin; oral
4.1
17.0
58
178
C03CA01
ATC
furosemide; systemic
4.3
16.9
51
143
R55
ICD-10 Finland
Syncope and collapse
5.3
16.8
37
80
L28
ICPC
Limited function/disability (L)
4.6
16.8
45
115
XF400
NOMESCO Finland
ECG with 12 standard connections
4.5
16.7
47
125
N05AN01
ATC
lithium; oral
15.2
16.5
27
20
TPH04
NOMESCO Finland
Cathetrisation of vein
3.7
16.5
68
238
Z2445
NOMESCO Finland
Psychologist
6.4
16.3
29
51
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.6
16.2
43
109
P74
ICPC
Anxiety disorder/anxiety state
5.3
16.0
35
75
UKC02
NOMESCO Finland
Cystoscopy
5.2
15.8
36
80
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
6.4
15.8
28
49
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.1
15.7
119
599
R42
ICD-10 Finland
Dizziness and giddiness
3.7
15.4
60
201
S06.0
ICD-10 Finland
Concussion
4.1
15.2
48
139
N06AA09
ATC
amitriptyline; systemic
5.2
15.0
34
75
F19.1
ICD-10 Finland
Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances, harmful use
61.0
15.0
17
*
A04
ICPC
Weakness/tiredness general
3.8
14.8
54
173
F90.0
ICD-10 Finland
Disturbance of activity and attention
5.2
14.8
33
72
N05BA12
ATC
alprazolam; oral
4.4
14.8
42
112
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.0
14.6
103
493
R96
ICPC
Asthma
5.1
14.5
33
73
A28
ICPC
Limited function/disability NOS
4.7
14.4
37
91
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
4.4
14.3
40
105
N03AF01
ATC
carbamazepine; oral, rectal
7.3
14.3
22
33
R06.0
ICD-10 Finland
Dyspnoea
3.2
14.0
73
293
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.1
13.9
22
34
N03AX11
ATC
topiramate; oral
7.1
13.9
22
34
R02
ICPC
Shortness of breath/dyspnoea
4.2
13.8
41
113
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
36.6
13.7
17
5
Z3231
NOMESCO Finland
Registered nurse
3.1
13.7
78
329
F20.9
ICD-10 Finland
Schizophrenia, unspecified
12.7
13.7
24
21
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
5.7
13.5
27
53
A01
ICPC
Pain general/multiple sites
4.5
13.5
36
91
WYA30
NOMESCO Finland
Treatment of a patient needing special arrangements
4.2
13.5
40
110
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
3.8
13.4
48
151
N05AH02
ATC
clozapine; systemic
12.1
13.4
24
22
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.1
13.3
41
116
F33.8
ICD-10 Finland
Other recurrent depressive disorders
30.5
13.2
17
6
F39
ICD-10 Finland
Unspecified mood [affective] disorder
11.5
13.1
24
23
J18.9
ICD-10 Finland
Pneumonia, unspecified
3.4
13.1
59
216
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.5
13.0
35
89
T90
ICPC
Diabetes non-insulin dependent
3.5
13.0
52
176
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
6.5
12.9
22
37
S29
ICPC
Skin symptom/complaint other
3.4
12.8
56
201
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
34.3
12.8
16
5
WX892
NOMESCO Finland
Monitored bed care
5.3
12.7
27
56
K59.09
ICD-10 Finland
Constipation, unspecified
6.1
12.7
23
41
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
4.5
12.6
33
82
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
10.6
12.6
24
25
F61
ICD-10 Finland
Mixed and other personality disorders
137.4
12.6
13
*
N02BF02
ATC
pregabalin; oral
5.3
12.5
27
57
R11
ICD-10 Finland
Nausea and vomiting
4.3
12.5
35
92
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.0
12.3
69
286
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
28.5
12.2
16
6
N06AX05
ATC
trazodone; oral
10.5
12.1
23
24
P72
ICPC
Schizophrenia
10.5
12.1
23
24
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
3.8
12.1
41
124
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
49.5
12.0
14
*
SPAT1254
SPAT
Administration of medicine
3.6
12.0
46
151
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.0
12.0
69
290
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.5
11.9
47
157
XF600
NOMESCO Finland
Bloodpressure measurement
6.0
11.9
22
40
F41.8
ICD-10 Finland
Other specified anxiety disorders
6.0
11.9
22
40
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
13.6
11.9
20
16
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
17.7
11.9
18
11
N05CF02
ATC
zolpidem; oral
3.2
11.8
58
222
R53
ICD-10 Finland
Malaise and fatigue
2.9
11.8
77
346
N02AX02
ATC
tramadol; systemic, rectal
2.7
11.8
107
570
N05AB01
ATC
dixyrazine; systemic
68.7
11.7
13
*
F60.0
ICD-10 Finland
Paranoid personality disorder
+∞
11.6
11
*
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
10.5
11.5
22
23
R33
ICD-10 Finland
Retention of urine
10.5
11.5
22
23
R03BB04
ATC
tiotropium bromide; inhalant
5.4
11.5
24
49
N06BA04
ATC
methylphenidate; oral
4.7
11.4
28
66
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
5.1
11.3
25
54
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
14.9
11.2
18
13
A02BA02
ATC
ranitidine; systemic
3.4
11.1
46
158
R52.9
ICD-10 Finland
Pain, unspecified
3.8
11.1
38
115
G43.9
ICD-10 Finland
Migraine, unspecified
3.8
11.1
37
110
N04AA02
ATC
biperiden; systemic
16.6
11.0
17
11
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
5.3
11.0
23
47
SPAT1240
SPAT
Therapeutic discussion
3.2
10.9
51
189
N30.0
ICD-10 Finland
Acute cystitis
3.1
10.9
53
201
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
19.0
10.9
16
9
M54.5
ICD-10 Finland
Low back pain
2.6
10.9
107
587
ZY000
NOMESCO Finland
Hospital inpatient
13.9
10.9
18
14
103
Kela drug reimbursment
Diabetes, insulin-treated
3.1
10.9
56
220
SPAT1307
SPAT
Psychosocial counselling and guidance
4.0
10.8
34
97
R51.80
ICD-10 Finland
Headache
2.9
10.8
64
272
Z72.2
ICD-10 Finland
Drug use
63.1
10.7
12
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
15.2
10.7
17
12
H02AB07
ATC
prednisone; oral
3.6
10.7
40
129
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
12.9
10.6
18
15
F10.25
ICD-10 Finland
Alcohol dependence continuous use
12.9
10.6
18
15
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
9.5
10.5
21
24
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.4
10.5
44
152
K10.3
ICD-10 Finland
Alveolitis of jaws
4.3
10.5
29
75
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
8.1
10.5
23
31
Z01.8
ICD-10 Finland
Other specified special examinations
2.8
10.4
65
283
L03
ICPC
Low back symptom/complaint
2.6
10.4
83
410
X78
ICD-10 Finland
Intentional self-harm by sharp object
24.8
10.4
14
6
A04AA01
ATC
ondansetron; systemic, rectal
4.7
10.3
25
58
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.6
10.3
37
116
X59
ICD-10 Finland
Exposure to unspecified factor
2.8
10.3
63
272
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
5.2
10.2
22
46
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
4.5
10.2
26
63
A02BC01
ATC
omeprazole; systemic
2.7
10.2
73
341
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.7
10.1
35
107
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.7
10.1
72
336
A46
ICD-10 Finland
Erysipelas
3.5
10.1
38
123
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
10.3
10.0
19
20
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
11.4
10.0
18
17
R52.2
ICD-10 Finland
Other chronic pain
8.0
10.0
22
30
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
21.2
9.9
14
7
R60.0
ICD-10 Finland
Localized oedema
3.9
9.9
31
88
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.8
9.7
32
94
F10.20
ICD-10 Finland
Alcohol dependence currently independent
10.8
9.7
18
18
H01
ICPC
Ear pain/earache
3.2
9.7
44
160
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
4.6
9.6
24
57
P06
ICPC
Sleep disturbance
3.1
9.6
45
166
N06CA01
ATC
amitriptyline and psycholeptics; systemic
3.8
9.6
32
95
R4110
NOMESCO Finland
Physiotherapy
2.6
9.6
70
329
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
5.5
9.5
19
37
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.9
9.5
53
216
P28
ICPC
Limited function/disability (P)
31.5
9.5
12
*
N05AD03
ATC
melperone; systemic
104.3
9.5
10
*
3018X
ICD-9 Finland
Personality disorders, Other personality disorders[MUU TAI SEKAMUOTOINEN PERSOONALLISUUSHÄIRIÖ]
104.3
9.5
10
*
F31.31
ICD-10 Finland
Bipolar disorder depressive episode with somatic syndrome
104.3
9.5
10
*
P19
ICPC
Drug abuse
22.9
9.5
13
6
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
2.4
9.4
135
862
Z91.5
ICD-10 Finland
Personal history of self-harm
+∞
9.4
9
*
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
+∞
9.4
9
*
S18
ICPC
Laceration/cut
2.4
9.4
104
592
XKD00
NOMESCO Finland
Uroflowmetry
4.3
9.3
25
63
R05
ICPC
Cough
2.6
9.3
74
362
TKC20
NOMESCO Finland
Catheterisation of bladder
5.1
9.3
20
42
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
5.1
9.3
20
42
ZXA05
NOMESCO Finland
Left side
2.8
9.2
56
239
L17
ICPC
Foot/toe symptom/complaint
2.5
9.2
76
378
U07
ICPC
Urine symptom/complaint other
4.5
9.2
23
55
G40.9
ICD-10 Finland
Epilepsy, unspecified
8.5
9.1
19
24
N05AA01
ATC
chlorpromazine; systemic, rectal
19.6
9.0
13
7
W17
ICD-10 Finland
Other fall from one level to another
5.2
9.0
19
39
A03FA01
ATC
metoclopramide; systemic, rectal
2.7
9.0
62
282
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.7
9.0
20
28
D10
ICPC
Vomiting
3.6
8.9
32
100
SPAT1104
SPAT
Monitoring of emergency patient
4.7
8.8
21
48
F50.9
ICD-10 Finland
Eating disorder, unspecified
14.8
8.8
14
10
WZC00
NOMESCO Finland
Treatment plan or consultation
2.4
8.8
95
532
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
8.8
78
400
K02.1
ICD-10 Finland
Caries of dentine
2.6
8.8
166
1185
F19.20
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances currently independent
52.1
8.7
10
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
9.6
8.7
17
19
J01FF01
ATC
clindamycin; systemic
2.5
8.6
74
373
WX290
NOMESCO Finland
Other blockage of nerve
2.4
8.6
148
1008
P01AB01
ATC
metronidazole; oral, rectal
2.3
8.6
107
636
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
28.8
8.6
11
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.9
8.5
27
77
F10.24
ICD-10 Finland
Alcohol depence active use
13.5
8.5
14
11
N05BA02
ATC
chlordiazepoxide; systemic
13.5
8.5
14
11
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
3.1
8.4
38
137
A10BH01
ATC
sitagliptin; oral
4.5
8.4
21
50
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
8.3
64
306
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
15.2
8.3
13
9
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
15.2
8.3
13
9
N05CD02
ATC
nitrazepam; oral
15.2
8.3
13
9
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
3.8
8.3
26
74
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
3.3
8.2
34
116
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.3
8.2
113
696
A02BC02
ATC
pantoprazole; systemic
2.3
8.2
148
1020
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
4.4
8.2
21
51
N06AX26
ATC
vortioxetine; oral
3.3
8.2
33
111
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
18.0
8.2
12
7
E950A
ICD-9 Finland
Suicide and self-inflicted poisoning by solid or liquid substances
18.0
8.2
12
7
F93.89
ICD-10 Finland
Other childhood emotional disorders
18.0
8.2
12
7
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
10.6
8.2
15
15
J01EA01
ATC
trimethoprim; systemic
2.5
8.2
66
323
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
34.7
8.1
10
*
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
34.7
8.1
10
*
F19.24
ICD-10 Finland
Addiction relationship caused by several drugs in combination and by other psychoactive substances active addiction
34.7
8.1
10
*
Z2221
NOMESCO Finland
Medical doctor
2.4
8.1
74
382
Z3226
NOMESCO Finland
Physiotherapist
2.8
8.1
48
201
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
3.6
8.1
29
90
N02AA05
ATC
oxycodone; systemic
3.1
8.1
38
140
R03AK06
ATC
salmeterol and fluticasone; inhalant
3.0
8.1
41
158
X58
ICD-10 Finland
Exposure to other specified factors
2.7
8.1
49
208
N06AG02
ATC
moclobemide; oral
7.1
8.1
19
29
N06AA12
ATC
doxepin; systemic
4.7
8.1
19
43
M79.1
ICD-10 Finland
Myalgia
2.7
8.0
50
215
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
7.4
8.0
18
26
R00.0
ICD-10 Finland
Tachycardia, unspecified
4.6
7.8
19
44
A10AB05
ATC
insulin aspart; parenteral
3.9
7.8
24
67
XF404
NOMESCO Finland
Ambulatory ECG
4.3
7.8
21
53
D07AC01
ATC
betamethasone; topical
2.3
7.8
85
474
IFB01
NOMESCO Finland
Electroconvulsive Therapy (ECT)
46.6
7.8
9
*
Z72.8
ICD-10 Finland
Other problems related to lifestyle
46.6
7.8
9
*
IAB07
NOMESCO Finland
Consultation concerning a patient with self-harm intention
46.6
7.8
9
*
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.1
7.7
22
58
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
7.7
64
316
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
4.4
7.7
20
49
P98
ICPC
Psychosis NOS/other
19.2
7.7
11
6
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
19.2
7.7
11
6
N06AX17
ATC
milnacipran; oral
19.2
7.7
11
6
SAA01
NOMESCO Finland
Simple examination of mouth
2.8
7.7
188
1463
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.9
7.6
41
163
U02
ICPC
Urinary frequency/urgency
2.9
7.5
39
152
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
14.0
7.5
12
9
9694A
ICD-9 Finland
Poisoning by psychotropic agents, Benzodiazepine-based tranquillisers
82.7
7.5
8
*
A10BA02
ATC
metformin; oral
2.5
7.5
54
250
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
7.3
7.5
17
25
L12
ICPC
Hand/finger symptom/complaint
2.6
7.5
50
223
J45
ICD-10 Finland
Asthma
3.2
7.4
32
112
F31
ICD-10 Finland
Bipolar affective disorder
11.4
7.4
13
12
A10AE04
ATC
insulin glargine; parenteral
3.5
7.4
27
85
N17
ICPC
Vertigo/dizziness
3.2
7.4
31
107
F60.2
ICD-10 Finland
Dissocial personality disorder
+∞
7.3
7
*
F60.1
ICD-10 Finland
Schizoid personality disorder
+∞
7.3
7
*
F60.7
ICD-10 Finland
Dependent personality disorder
+∞
7.3
7
*
SPAT1167
SPAT
Insertion of urinary catheter
16.4
7.3
11
7
W0A12
NOMESCO Finland
Planned therapy visit for psychiatric disease
16.4
7.3
11
7
SPAT1222
SPAT
Counselling/guidance promoting independent living
3.0
7.3
34
125
F51.0
ICD-10 Finland
Nonorganic insomnia
2.5
7.2
56
267
P15
ICPC
Chronic alcohol abuse
6.4
7.2
18
30
SPAT1255
SPAT
Intravenous administration of medicine
4.3
7.2
19
47
Z04.4
ICD-10 Finland
Examination and observation following alleged rape and seduction
31.1
7.2
9
*
F45.0
ICD-10 Finland
Somatization disorder
20.8
7.2
10
5
183
Kela drug reimbursment
Lamotrigin and topiramate
20.8
7.2
10
5
SGA02
NOMESCO Finland
Opening and preparing the root canals
2.7
7.2
43
181
Z53.2
ICD-10 Finland
Procedure not carried out because of patient's decision for other and unspecified reasons
9.3
7.2
14
16
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
9.3
7.2
14
16
D01
ICPC
Abdominal pain/cramps general
2.8
7.1
38
150
J46
ICD-10 Finland
Status asthmaticus
10.5
7.1
13
13
EBA00
NOMESCO Finland
Extraction of tooth
2.2
7.1
97
587
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
5.8
7.1
19
35
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.8
7.1
22
62
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.6
7.0
48
216
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.4
7.0
55
264
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.0
7.0
20
53
N02BF01
ATC
gabapentin; oral
3.4
7.0
26
83
F41.09
ICD-10 Finland
UNS Panic Syndrome
4.4
7.0
18
44
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
2.2
6.9
89
525
N30.9
ICD-10 Finland
Cystitis, unspecified
3.9
6.9
21
58
OAB43, ,
SPAT
0.4
6.9
37
764
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.5
6.9
51
238
SPAT1216
SPAT
Assessment of functional ability
3.2
6.9
29
100
K92.0
ICD-10 Finland
Haematemesis
9.8
6.9
13
14
EBA30
NOMESCO Finland
Extraction of root of tooth
4.5
6.9
17
40
M54.4
ICD-10 Finland
Lumbago with sciatica
2.4
6.9
54
259
SPAT1262
SPAT
Handing over of treatment supplies
2.8
6.9
37
147
K59.0
ICD-10 Finland
Constipation
4.1
6.9
19
49
D06
ICPC
Abdominal pain localized other
3.1
6.8
30
106
A07AA09
ATC
vancomycin; oral
17.3
6.8
10
6
R51
ICD-10 Finland
Headache
3.4
6.8
25
79
F44.7
ICD-10 Finland
Mixed dissociative [conversion] disorders
41.3
6.8
8
*
P04
ICPC
Feeling/behaving irritable/angry
41.3
6.8
8
*
F25.10
ICD-10 Finland
Schizoaffective syndrome, depressive type with only concomitant bipolar and schizophrenic symptoms
41.3
6.8
8
*
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
5.8
6.8
18
33
F43.1
ICD-10 Finland
Post-traumatic stress disorder
4.3
6.8
18
45
NA1AD
NOMESCO Finland
Cervical spine CT examination
4.3
6.8
18
45
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.6
6.8
23
69
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.1
6.7
30
107
R95
ICPC
Chron obstructive pulmonary disease
23.3
6.7
9
*
2968A
ICD-9 Finland
Affective psychoses, Manic-depressive psychosis, other and unspecified
23.3
6.7
9
*
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.7
6.7
41
174
A97
ICPC
No disease
2.4
6.7
51
241
B18.2
ICD-10 Finland
Chronic viral hepatitis C
12.8
6.7
11
9
Y57
ICD-10 Finland
Adverse effects in the therapeutic use of other and unspecified drugs and medicaments
7.2
6.6
15
22
J01MA02
ATC
ciprofloxacin; systemic
2.1
6.6
84
492
A02BC05
ATC
esomeprazole; systemic
2.1
6.6
92
558
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.7
6.6
40
169
SPAT1234
SPAT
Support of social functional capacity
6.5
6.6
16
26
IGY99
NOMESCO Finland
Other psychiatric treatment contact
6.0
6.6
17
30
A99
ICPC
Disease/condition unspecnature/site
3.3
6.6
26
86
L05
ICPC
Flank/axilla symptom/complaint
4.0
6.5
19
51
G44.2
ICD-10 Finland
Tension-type headache
2.5
6.5
46
210
SPAT1058
SPAT
PEF monitoring instruction
3.7
6.5
21
61
IAB08
NOMESCO Finland
Consultation concerning a patient who has attempted suicide
71.8
6.5
7
*
X84
ICD-10 Finland
Intentional self-harm by unspecified means
71.8
6.5
7
*
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
14.9
6.5
10
7
F10.9
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Unspecified mental and behavioural disorder
14.9
6.5
10
7
F20.09
ICD-10 Finland
Paranoid schizophrenia UNS
14.9
6.5
10
7
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
8.6
6.4
13
16
A03FA02
ATC
cisapride; oral, rectal
4.1
6.4
18
47
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
9.7
6.4
12
13
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
11.5
6.4
11
10
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.2
6.4
26
88
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
6.3
79
458
Y94.8
ICD-10 Finland
Other leisure activity accident
7.4
6.3
14
20
XF402
NOMESCO Finland
ECG with work load test
3.6
6.3
21
62
V03AA01, ,
ATC
18.7
6.3
9
5
S51.8
ICD-10 Finland
Open wound of other parts of forearm
18.7
6.3
9
5
M89.0
ICD-10 Finland
Algoneurodystrophy
18.7
6.3
9
5
N05AE05
ATC
lurasidone; oral
+∞
6.3
6
*
EBA05
NOMESCO Finland
Complicated extraction of tooth
2.2
6.3
63
335
N06AA22, ,
ATC
27.5
6.3
8
*
H50.1
ICD-10 Finland
Divergent concomitant strabismus
27.5
6.3
8
*
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
27.5
6.3
8
*
R31
ICD-10 Finland
Unspecified haematuria
4.0
6.2
18
48
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.8
6.2
34
136
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.9
6.2
30
112
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
8.0
6.2
13
17
F43.20
ICD-10 Finland
Adaptation disorder with short-term depression
8.0
6.2
13
17
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.4
6.2
23
73
H03AA01
ATC
levothyroxine sodium; systemic
2.3
6.2
58
299
ZXE10
NOMESCO Finland
More than one and less than three hours
2.1
6.2
79
461
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.0
6.2
28
101
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
13.0
6.1
10
8
F22.0
ICD-10 Finland
Delusional disorder
13.0
6.1
10
8
A02BA03
ATC
famotidine; systemic
9.0
6.1
12
14
ZXD05
NOMESCO Finland
Urgent procedure
2.1
6.1
80
471
T82
ICPC
Obesity
4.1
6.1
17
44
WX882
NOMESCO Finland
High dependency care
10.4
6.1
11
11
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.9
6.1
18
49
E66.00
ICD-10 Finland
Metabolic syndrome
3.9
6.1
18
49
SAA04
NOMESCO Finland
Special examination of mouth
3.5
6.0
21
64

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
41
54
9.08
30.38
2.8
1.6
—
—
—
0
0
63
184
4.38
20.04
1.8
1.6
957.84
1203.49
nmol/l
1.71
49
147
130
633
3.53
19.14
6.2
6.2
1.21
1.21
mmol/l
0.09
109
535
51
132
4.71
18.85
2.8
1.5
—
—
—
0
0
121
571
3.45
18.60
6.6
5.3
1.22
1.22
mmol/l
0.04
109
536
53
143
4.55
18.58
2.8
1.5
—
—
—
0
0
53
143
4.55
18.58
2.9
1.5
—
—
—
0
0
53
145
4.48
18.23
2.9
1.5
—
—
—
0
0
46
113
4.87
18.08
2.7
1.5
—
—
—
0
0
149
811
3.52
17.91
5.9
5.6
9.78
10.42
umol/l
0.31
139
765
40
88
5.32
17.86
2.9
1.6
—
—
—
0
0
120
584
3.28
17.16
4.3
4.8
36.82
37.18
g/l
0.30
113
562
95
410
3.29
16.50
3.2
3.0
7.52
8.19
mmol/l
0.52
81
362
47
128
4.39
16.16
5.5
6.6
104.85
104.44
mmol/l
0.19
47
128
106
497
3.16
15.86
3.4
2.7
46.79
57.88
u/l
2.56
96
463
44
118
4.40
15.39
4.8
11.0
0.06
1.15
mmol/l
1.06
38
96
54
169
3.90
15.32
2.1
1.5
—
—
—
0
0
38
91
4.83
15.29
4.3
2.9
—
—
—
0
0
108
522
3.07
15.17
2.2
1.7
98.07
100.94
pmol/l
0.22
57
253
49
145
4.05
15.02
3.0
1.5
—
—
—
0
0
22
13
18.61
14.63
2.1
1.5
—
—
—
0
0
34
85
4.54
12.91
6.1
6.2
—
—
—
0
0
47
152
3.65
12.57
2.5
1.9
323.45
406.33
nmol/l
2.13
42
144
156
984
2.95
12.55
14.6
8.7
4.54
3.93
e9/l
2.22
137
868
27
57
5.25
12.49
3.7
16.6
—
—
—
0
0
45
145
3.64
12.07
3.0
2.3
26.26
35.59
u/l
0.72
39
118
108
576
2.70
11.90
5.4
9.0
1.04
1.13
inr
1.31
33
204
180
1251
3.28
11.71
8.8
6.6
79.87
73.52
u/l
1.11
168
1170
54
201
3.23
11.52
2.1
3.3
0.81
0.82
mmol/l
0.54
49
188
24
50
5.26
11.24
2.5
2.1
0.63
0.69
%
0.45
24
50
82
390
2.74
11.21
4.2
3.1
7.39
7.40
ph
0.18
15
81
145
913
2.68
11.14
6.6
4.3
6.71
6.29
mmol/l
1.16
139
817
82
393
2.72
11.01
4.2
2.5
0.32
0.21
e6/l
0.30
64
280
24
53
4.95
10.52
2.6
2.0
2.25
1.55
%
0.94
24
53
138
868
2.55
10.31
9.9
5.8
0.20
0.18
e9/l
0.43
122
786
101
553
2.51
10.15
5.5
3.1
53.88
112.16
e6/l
0.42
72
354
133
837
2.46
9.71
8.4
5.5
0.04
0.04
e9/l
0.46
117
752
26
66
4.33
9.62
5.3
8.2
1.87
1.44
%
0.65
26
66
75
366
2.58
9.51
2.1
1.9
3.05
2.79
mg/l
0.46
64
317
63
282
2.72
9.50
3.7
2.4
515.30
561.12
mosm/kgh2o
0.84
56
240
132
836
2.42
9.39
8.5
5.5
0.57
0.54
e9/l
1.05
116
750
49
194
2.96
9.27
1.8
2.5
8.51
8.88
umol/l
0.03
35
169
80
407
2.51
9.26
4.2
2.5
—
—
—
0
0
88
473
2.42
8.98
2.4
3.1
2.34
2.35
mmol/l
0.41
82
429
68
326
2.56
8.87
7.6
4.0
—
—
—
0
0
84
445
2.42
8.83
4.7
2.6
28.40
64.33
e6/l
0.52
68
325
25
66
4.14
8.79
5.2
8.2
0.58
0.68
%
0.68
25
66
82
431
2.43
8.76
4.1
2.2
—
—
—
0
0
58
262
2.64
8.50
1.7
1.5
422.17
436.48
pmol/l
0.17
47
236
134
884
2.29
8.28
8.4
5.5
2.10
1.96
e9/l
0.88
122
811
25
69
3.95
8.27
4.7
11.2
—
—
—
0
0
122
775
2.27
8.25
8.7
5.7
0.64
0.68
%
0.32
108
728
33
111
3.32
8.18
2.0
1.5
376.79
309.20
mu/l
0.50
28
98
76
400
2.37
7.98
11.0
6.6
—
—
—
0
0
124
803
2.23
7.88
9.4
6.0
7.77
8.08
%
0.69
112
763
124
807
2.21
7.73
8.8
5.5
2.61
2.80
%
0.41
112
763
127
835
2.21
7.71
8.5
5.3
57.28
56.48
%
0.36
115
796
124
810
2.20
7.62
8.6
5.9
—
—
—
0
0
184
1428
2.65
7.34
6.1
4.0
14.28
14.44
pmol/l
0.41
173
1331
48
212
2.61
7.28
2.5
2.5
2.40
2.42
mmol/l
0.55
43
187
52
241
2.51
7.14
5.2
2.6
42.16
194.50
ng/l
0.82
31
144
17
39
4.64
7.09
3.5
1.4
—
—
—
0
0
43
182
2.69
7.09
1.7
1.5
—
—
—
0
0
67
350
2.31
7.05
3.6
3.8
3.45
11.75
mg/mmol
1.89
47
229
126
846
2.13
7.01
9.0
5.5
28.55
29.47
%
0.48
114
809
64
330
2.32
6.92
3.3
3.3
1053.53
279.56
mg/l
0.34
46
223
15
22
7.23
6.64
18.5
14.4
995.80
708.14
nmol/l
1.28
15
22
15
22
7.23
6.64
25.3
17.0
1628.20
1231.36
nmol/l
0.99
15
22
44
195
2.57
6.60
2.0
2.2
—
—
—
0
0
59
302
2.30
6.45
1.7
1.4
17.42
20.49
nmol/l
0.94
51
266
27
93
3.17
6.42
1.4
1.2
—
—
—
0
0
18
48
3.99
6.22
1.4
1.1
—
—
—
0
0
48
229
2.40
6.14
3.8
2.3
5.64
3.19
e6/l
0.38
25
112
150
1124
2.02
5.66
4.4
2.9
—
—
—
0
0
16
42
4.03
5.64
2.7
17.3
0.87
0.88
%
0.02
16
37
16
43
3.93
5.47
1.3
1.3
—
—
—
0
0
12
18
6.98
5.33
2.1
3.3
—
—
—
0
0
111
763
1.91
5.28
11.8
8.1
0.00
0.00
e9/l
0.84
89
639
125
897
1.90
5.17
3.1
2.6
75.27
81.62
ug/l
0.33
115
852
163
1283
2.01
5.03
4.6
3.5
9.14
8.72
mm/h
0.24
148
1199
13
24
5.68
4.99
1.5
1.5
—
—
—
0
0
199
1698
2.60
4.90
7.6
4.5
1.77
1.74
mu/l
0.15
188
1601
17
52
3.46
4.85
1.2
1.2
2.88
7.23
e6/l
—
8
40
17
52
3.46
4.85
1.2
1.3
17.50
26.84
e6/l
—
8
43
15
43
3.67
4.70
2.8
16.9
2.35
1.69
%
0.60
15
37
7
5
14.39
4.60
4.1
2.4
36014.29
36860.00
ug/l
—
7
5
7
5
14.39
4.60
1.6
2.6
19.70
23.24
umol/l
—
7
5
186
1556
2.18
4.58
6.8
4.1
39.67
37.73
mmol/mol
1.51
172
1480
63
373
1.96
4.57
3.3
2.9
—
—
—
0
0
171
1390
1.99
4.52
5.9
2.8
45.04
40.83
u/l
0.44
162
1341
10
15
6.92
4.52
2.1
1.3
65.70
69.22
%
—
10
15
153
1207
1.85
4.34
6.1
3.8
—
—
—
0
0
20
73
2.91
4.31
4.0
3.3
24.79
24.89
mmol/l
0.04
20
73
14
34
4.32
4.29
5.6
3.1
—
—
—
0
0
15
46
3.42
4.27
8.1
4.4
—
—
—
0
0
79
515
1.83
4.23
4.6
2.7
13.50
37.51
ng/l
1.53
47
260
17
57
3.15
4.22
2.4
1.9
—
—
—
0
0
65
401
1.88
4.13
2.2
1.6
0.65
0.73
mg/l
0.30
46
296
27
119
2.44
4.06
3.6
4.3
0.89
0.89
%
—
9
37
16
53
3.17
4.05
4.3
2.2
—
—
—
0
0
17
59
3.04
3.99
1.4
1.3
—
—
—
0
0
11
322
0.31
3.93
1.2
1.4
—
—
—
0
0
49
280
1.96
3.89
2.0
2.4
107.67
122.23
ug/g
0.13
36
214
10
19
5.46
3.87
1.4
1.1
—
—
—
0
0
25
109
2.46
3.85
3.8
3.5
—
—
—
0
0
11
24
4.76
3.80
1.4
2.6
9.11
8.02
kpa
0.59
11
24
59
362
1.86
3.78
4.8
2.6
—
—
—
0
0
25
112
2.39
3.64
3.7
4.4
0.17
0.17
%
—
6
29
208
1866
2.70
3.64
23.0
10.1
16.21
19.81
mg/l
1.40
183
1403
10
21
4.93
3.60
1.9
2.6
25.86
25.12
mmol/l
—
10
21
25
113
2.37
3.57
3.6
4.1
0.78
0.67
%
—
9
33
66
428
1.77
3.51
2.0
1.7
1.58
1.42
mmol/l
0.78
59
373
193
1693
2.04
3.34
5.9
3.4
6.20
5.65
mmol/l
2.71
182
1581
10
25
4.14
3.12
2.8
2.1
—
—
—
0
0
86
619
1.63
3.05
2.6
2.1
—
—
—
0
0
50
313
1.77
2.96
2.2
1.6
—
—
—
0
0
6
9
6.81
2.88
1.3
1.1
—
—
—
0
0
30
161
2.00
2.83
1.2
1.2
—
—
—
0
0
113
884
1.56
2.75
4.2
3.0
0.00
0.01
estimate
0.50
21
188
36
210
1.85
2.67
1.3
1.3
—
—
—
0
0
57
381
1.67
2.65
3.1
3.0
1.01
1.02
kg/l
—
5
55
7
15
4.78
2.62
1.9
2.8
—
—
—
0
0
12
42
2.96
2.59
3.7
1.7
—
—
—
0
0
12
44
2.83
2.59
1.4
1.5
—
—
—
0
0
5
7
7.27
2.56
1.8
4.3
10.20
8.00
mmol/l
—
5
7
52
343
1.67
2.54
1.3
1.3
87.44
30.93
iu/ml
—
10
119
7
16
4.48
2.49
7.1
1.4
—
—
—
0
0
28
154
1.94
2.48
2.1
2.5
5471.45
2170.99
u/l
—
6
74
10
32
3.22
2.47
1.4
1.1
38.42
40.53
g/l
—
10
32
110
877
1.50
2.33
5.3
4.2
0.00
0.01
estimate
0.50
24
181
111
887
1.50
2.33
3.9
3.0
0.00
0.00
estimate
-0.00
24
176
15
66
2.36
2.30
4.4
2.0
—
—
—
0
0
22
115
2.01
2.25
1.1
1.2
—
—
—
0
0
22
116
1.99
2.20
1.7
2.3
1.76
1.64
%
0.30
17
109
20
102
2.06
2.18
2.3
2.7
1.23
1.23
mmol/l
0.09
15
94
9
30
3.08
2.17
1.4
1.4
—
—
—
0
0
29
169
1.82
2.17
1.2
1.4
—
—
—
0
0
7
19
3.77
2.17
1.0
1.2
—
—
—
0
0
6
14
4.37
2.16
1.0
1.3
—
—
—
0
0
6
14
4.37
2.16
1.7
1.5
—
—
—
0
0
16
75
2.22
2.14
3.1
1.4
—
—
—
0
0
11
43
2.64
2.11
4.5
15.4
1.50
1.19
mmol/l
0.48
11
34
5
10
5.09
2.08
6.2
4.3
—
—
—
0
0
59
421
1.55
2.07
1.7
1.3
2.30
2.19
g/l
0.23
37
275
91
716
1.46
1.98
2.0
1.8
—
—
—
0
0
61
803
0.67
1.91
2.6
2.3
—
—
—
0
0
16
79
2.10
1.90
1.4
2.3
9.38
6.61
ug/l
—
9
70
64
474
1.49
1.88
1.6
1.3
1.91
1.86
u/ml
0.01
13
140
16
80
2.08
1.85
2.4
2.4
80.60
71.34
e9/l
—
10
56
5
12
4.24
1.83
1.6
1.3
—
—
—
0
0
9
35
2.64
1.82
7.9
4.1
3.73
3.83
mmol/l
—
9
35
7
23
3.11
1.81
1.1
1.3
208.89
53.52
mu/l
—
7
18
11
47
2.41
1.80
1.5
1.9
—
—
—
0
0
6
18
3.40
1.76
1.3
2.6
—
—
—
0
0
22
126
1.83
1.75
1.6
1.3
11.36
19.26
iu/l
0.80
16
104
29
182
1.68
1.71
2.7
2.0
20.96
24.07
%
0.42
23
161
7
157
0.43
1.62
1.3
1.8
—
—
—
0
0
6
20
3.05
1.59
1.3
1.4
—
—
—
0
0
18
100
1.87
1.58
1.2
1.1
—
132.20
titre
—
0
5
19
108
1.83
1.56
3.4
2.4
—
—
—
0
0
47
339
1.49
1.56
1.3
1.3
1.00
10.56
u/ml
3.12
14
153
6
21
2.91
1.51
1.3
1.1
—
—
—
0
0
29
190
1.60
1.46
1.8
1.6
—
—
—
0
0
5
16
3.17
1.44
1.2
1.4
92.06
90.54
%
—
5
16
21
330
0.60
1.43
1.6
1.4
—
—
—
0
0
17
98
1.80
1.35
1.5
1.3
—
—
—
0
0
17
98
1.80
1.35
2.4
2.8
—
—
—
0
0
39
279
1.48
1.35
1.5
1.4
213.33
441.90
titre
—
6
63
0
41
0.00
1.32
0.0
1.1
—
—
—
0
0
25
163
1.60
1.30
4.0
3.2
—
—
—
0
0
8
35
2.33
1.28
1.1
1.1
—
—
—
0
0
207
1970
1.71
1.25
15.5
8.2
29.30
27.59
u/l
0.47
202
1912
5
19
2.67
1.22
1.2
1.5
0.29
0.37
g/l
—
5
11
5
19
2.67
1.22
1.2
1.5
5.82
6.14
g/l
—
5
11
5
19
2.67
1.22
1.2
1.5
1.97
3.06
g/l
—
5
11
5
19
2.67
1.22
1.2
1.5
—
—
—
0
0
5
21
2.41
1.09
1.0
1.4
—
—
nmol/l
—
0
0
11
59
1.91
1.09
1.5
1.6
—
—
—
0
0
6
121
0.48
1.09
1.3
1.5
—
—
—
0
0
10
52
1.97
1.08
1.4
1.2
—
—
—
0
0
58
465
1.33
1.06
4.0
3.2
0.00
0.01
estimate
0.50
24
182
9
46
2.00
1.05
1.1
1.2
—
—
—
0
0
7
34
2.09
1.04
4.0
1.8
8.49
9.39
kpa
—
7
34
7
34
2.09
1.04
4.0
1.8
5.19
5.21
kpa
—
7
34
65
535
1.30
0.98
3.1
1.9
—
—
—
0
0
28
201
1.45
0.97
1.1
1.2
—
—
—
0
0
6
116
0.50
0.97
1.2
1.4
—
—
—
0
0
6
116
0.50
0.97
1.2
1.4
—
—
—
0
0
18
120
1.54
0.88
1.6
1.2
—
30.46
—
0
5
8
43
1.89
0.88
1.9
1.4
—
—
—
0
0
26
189
1.43
0.86
1.3
1.4
—
—
—
0
0
52
428
1.28
0.79
2.0
1.7
—
—
—
0
0
39
309
1.32
0.78
3.5
3.3
0.84
1.58
ug/l
3.86
32
284
15
99
1.55
0.78
1.3
1.3
—
—
—
0
0
16
108
1.52
0.76
1.6
1.5
152.17
315.61
miu/ml
—
6
62
9
57
1.60
0.72
1.4
1.1
—
—
—
0
0
9
57
1.60
0.72
2.1
1.1
—
—
—
0
0
5
29
1.74
0.64
1.0
1.0
—
—
—
0
0
0
20
0.00
0.60
0.0
1.2
—
—
—
0
0
187
1797
1.25
0.56
5.1
3.8
2.78
2.90
mmol/l
0.97
175
1697
185
1782
1.22
0.50
4.8
3.6
4.57
4.80
mmol/l
2.52
172
1691
14
185
0.74
0.45
1.4
1.4
—
—
—
0
0
5
31
1.63
0.43
1.2
1.6
0.38
0.67
g/l
—
5
23
5
31
1.63
0.43
1.4
1.1
—
—
—
0
0
8
57
1.42
0.42
14.8
5.4
—
—
—
0
0
0
15
0.00
0.41
0.0
2.6
—
42.43
—
0
6
0
15
0.00
0.41
0.0
1.4
—
0.95
—
0
15
0
16
0.00
0.41
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.7
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.48
0.40
2.4
1.8
13.54
13.25
%
—
5
34
0
18
0.00
0.40
0.0
1.2
—
—
—
0
0
11
80
1.39
0.39
5.0
2.0
0.09
0.10
e6/l
0.05
11
75
5
37
1.36
0.37
1.2
1.1
0.21
6.53
u/ml
—
5
25
15
118
1.29
0.34
1.4
1.4
—
—
—
0
0
60
656
0.88
0.32
1.7
1.7
—
—
—
0
0
22
259
0.83
0.30
1.9
1.9
—
—
—
0
0
15
182
0.81
0.27
2.9
2.3
0.59
0.74
ug/l
—
7
90
15
123
1.24
0.26
1.7
1.1
—
—
—
0
0
175
1707
1.12
0.24
4.0
3.3
1.53
1.29
mmol/l
3.56
159
1613
5
39
1.29
0.23
5.2
4.5
63.40
56.95
%
—
5
39
5
39
1.29
0.23
5.2
4.3
4.02
4.16
e9/l
—
5
39
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
1.50
—
0
13
0
13
0.00
0.21
0.0
1.5
—
5.50
—
0
13
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
14
121
1.17
0.15
1.1
1.1
—
—
—
0
0
57
540
1.07
0.15
3.6
2.7
—
—
—
0
0
8
97
0.82
0.14
5.1
2.5
21.62
43.38
u/ml
—
8
92
203
2009
1.12
0.13
21.4
9.5
—
—
—
0
0
55
524
1.07
0.12
2.2
1.7
—
—
—
0
0
179
1771
1.05
0.08
4.7
3.5
1.29
1.48
mmol/l
10.01
167
1678
19
176
1.09
0.08
1.3
1.3
253.67
132.76
iu/ml
—
6
70
173
1719
1.03
0.03
31.6
12.4
333.10
333.74
g/l
0.41
173
1710
213
2136
0.94
0.01
35.9
14.9
7.31
6.62
e9/l
6.35
208
2088
38
374
1.02
0.00
2.2
2.1
325.56
6915.36
umol/l
1.76
32
341
213
2132
0.98
0.00
35.2
14.8
40.77
40.91
%
0.20
202
2041
11
106
1.04
0.00
1.2
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
2.0
—
7.00
—
0
5
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
0.00
0.0
4.6
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
81.32
—
0
6
0
7
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.6
—
9.11
—
0
7
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint F5_PERSOTH and mortality.

Females

Parameter HR [95% CI] p-value
F5_PERSOTH 3.96 [2.86, 5.48] < 0.001
Birth year 0.997 [0.99, 1.01] 0.546

During the follow-up period (1.1.1998 — 31.12.2019), 122 out of 874 females with F5_PERSOTH died.

Males

Parameter HR [95% CI] p-value
F5_PERSOTH 3.707 [2.77, 4.95] < 0.001
Birth year 0.983 [0.97, 0.99] < 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 154 out of 864 males with F5_PERSOTH died.

Mortality risk

Mortality risk for people of age

years, who have F5_PERSOTH.

N-year risk Females Males
1 0.438% 0.701%
5 2.464% 4.344%
10 5.706% 9.585%
15 10.864% 17.3%
20 18.266% 27.732%

Relationships between endpoints

↥

Index endpoint: F5_PERSOTH – Other and unspecified disorders of adult personality and behaviour

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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