Chronic conjunctivitis

H7_CONJUNCTIVITISCHRON

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H10.4
  • Hospital discharge: ICD-9 3721
  • Cause of death: ICD-10 H10.4
  • Cause of death: ICD-9 3721

2 out of 7 registries used, show all original rules.

1129

4. Check minimum number of events

None

1129

5. Include endpoints

None

1129

6. Filter based on genotype QC (FinnGen only)

1129

Control definitions (FinnGen only)

Control exclude
H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H10
Name in latin
Conjunctivitis chronica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8152 4892 3233
Only index persons 7374 4515 2859
Unadjusted period prevalence (%)
Whole population 0.12 0.14 0.09
Only index persons 0.14 0.17 0.11
Median age at first event (years)
Whole population 38.99 44.07 31.30
Only index persons 40.61 44.61 34.30

-FinnGen-

Key figures

All Female Male
Number of individuals 1129 790 339
Unadjusted period prevalence (%) 0.23 0.27 0.15
Median age at first event (years) 48.21 48.22 48.18

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1001
Matched controls
10010
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S01GX01
ATC
cromoglicic acid; ophthalmic
20.6
323.0
624
745
H10.4
ICD-10 Finland
Chronic conjunctivitis
4503599627370496.0
323.0
984
*
S01GX05
ATC
lodoxamide; ophthalmic
112.0
205.2
219
25
H04.10
ICD-10 Finland
Dry eye syndrome
13.6
200.8
385
440
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
6.8
170.4
704
2577
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
5.0
117.7
535
1869
XQ800
NOMESCO Finland
Prick test
8.1
88.3
216
329
S01GX09
ATC
olopatadine; ophthalmic
26.3
83.4
117
50
H10.5
ICD-10 Finland
Blepharoconjunctivitis
28.6
78.9
108
42
S01GX02
ATC
levocabastine; ophthalmic
9.5
70.2
152
185
S01GX08
ATC
ketotifen; ophthalmic
12.2
56.8
106
96
H01.0
ICD-10 Finland
Blepharitis
7.1
56.2
146
234
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
7.7
54.3
133
195
S01GX04
ATC
nedocromil; ophthalmic
28.4
54.2
74
28
R06AE07
ATC
cetirizine; oral
2.8
52.5
554
3062
R06AX27
ATC
desloratadine; oral
3.1
52.5
393
1742
H10.1
ICD-10 Finland
Acute atopic conjunctivitis
16.1
50.4
83
56
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
4.8
48.1
174
416
H10.9
ICD-10 Finland
Conjunctivitis, unspecified
6.7
45.6
123
206
R06AX22
ATC
ebastine; oral
3.4
42.9
245
872
L20.0
ICD-10 Finland
Besnier prurigo
5.2
42.1
140
303
S01GX06
ATC
emedastine; ophthalmic
24.0
41.4
59
26
E0000UV
ATC
NA
2.5
41.1
481
2682
R01AD08
ATC
fluticasone; nasal
2.6
38.5
358
1741
J45.0
ICD-10 Finland
Predominantly allergic asthma
4.2
36.0
149
401
E000001
ATC
NA
2.8
35.6
270
1152
S01AA01
ATC
chloramphenicol; ophthalmic (antibiotics)
5.5
35.5
110
218
R06AX13
ATC
loratadine; oral
3.1
34.0
213
797
H02AB06
ATC
prednisolone; systemic
2.2
32.5
505
3121
XQ802
NOMESCO Finland
Epicutan test
6.6
31.9
85
139
S01XA18
ATC
ciclosporin; ophthalmic
31.2
31.9
42
14
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
28.0
31.7
43
16
R03DC03
ATC
montelukast; oral
2.9
30.4
216
874
R01AD09
ATC
mometasone; nasal
2.2
30.2
504
3177
R06AE09
ATC
levocetirizine; oral
3.0
30.1
197
755
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
5.2
29.8
97
203
S01BC03
ATC
diclofenac; ophthalmic
8.8
29.4
64
77
317
Kela drug reimbursment
Topical pimecrolimus and tacrolimus
16.4
29.2
47
30
H02AB07
ATC
prednisone; oral
2.9
28.9
194
754
R03AC02
ATC
salbutamol; inhalant
2.1
28.0
575
3912
J30.3
ICD-10 Finland
Other allergic rhinitis
5.7
26.7
79
148
J31.0
ICD-10 Finland
Chronic rhinitis
3.6
25.8
126
388
S01KA02
ATC
hypromellose; ophthalmic
9.0
24.8
53
62
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
5.8
24.3
70
127
D11AH01
ATC
tacrolimus; topical
20.1
23.6
35
18
S01AD03
ATC
aciclovir; ophthalmic
5.2
23.4
74
150
J01AA02
ATC
doxycycline; systemic
2.1
22.6
774
6195
J45.9
ICD-10 Finland
Asthma, unspecified
2.5
22.4
208
966
D07AA02
ATC
hydrocortisone; topical
2.6
21.3
179
785
C01CA24
ATC
epinephrine; parenteral
3.9
21.2
91
251
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
4.0
21.0
87
232
R03AC03
ATC
terbutaline; inhalant
2.6
20.7
171
743
H16.9
ICD-10 Finland
Keratitis, unspecified
8.9
20.3
43
50
D07AB02
ATC
hydrocortisone butyrate; topical
2.1
20.1
294
1677
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.9
19.8
131
499
R4110
NOMESCO Finland
Physiotherapy
2.1
19.7
290
1655
A02BC05
ATC
esomeprazole; systemic
1.9
19.6
412
2694
R06AX26
ATC
fexofenadine; oral
3.5
19.6
97
301
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
19.6
421
2774
R01AD01
ATC
beclometasone; nasal
2.5
19.5
175
793
F29
ICPC
Eye symptom/complaint other
3.2
19.3
108
366
XCK10
NOMESCO Finland
Photography of fundus of eye
2.9
19.3
123
456
N02AX02
ATC
tramadol; systemic, rectal
1.9
19.0
410
2695
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.3
19.0
189
903
E000002
ATC
NA
2.7
18.9
139
563
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
18.8
295
1718
XCH00
NOMESCO Finland
Eye pressure measurement
4.6
18.7
66
151
D07AB08
ATC
desonide; topical
2.7
18.7
138
561
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.2
18.6
216
1107
S01AX11
ATC
[U] ofloxacin; ophthalmic
5.0
18.6
60
125
J01FA06
ATC
roxithromycin; oral
1.9
18.5
415
2757
J01FA10
ATC
azithromycin; systemic
1.8
18.4
615
4664
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
18.2
263
1481
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
18.1
467
3246
H10
ICD-10 Finland
Conjunctivitis
3.3
18.1
94
303
CFA20
NOMESCO Finland
Biopsy of conjunctiva
53.5
18.0
21
*
H16.0
ICD-10 Finland
Corneal ulcer
4.3
17.9
67
163
J01DB01
ATC
cefalexin; oral
2.0
17.8
814
6848
3721A
ICD-9 Finland
Disorders of conjunctiva, Chronic conjunctivitis
+∞
17.8
17
*
R01AD12
ATC
fluticasone furoate; nasal
1.9
17.5
321
1976
ZXA00
NOMESCO Finland
Right side
2.0
17.5
277
1613
H16.2
ICD-10 Finland
Keratoconjunctivitis
14.2
17.3
29
21
R01AD05
ATC
budesonide; nasal
3.1
17.3
99
341
XCC00
NOMESCO Finland
Investigative irrigation of lacrimal passages
11.4
17.3
32
29
J05AB11
ATC
valaciclovir; oral
2.4
17.1
153
687
D11AX14
ATC
[U] tacrolimus; topical
26.1
16.9
23
9
R03BA02
ATC
budesonide; inhalant
2.2
16.8
200
1033
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
16.6
243
1368
D07AC13
ATC
mometasone; topical
1.9
16.6
291
1758
ZXA05
NOMESCO Finland
Left side
2.0
16.5
252
1445
R06.0
ICD-10 Finland
Dyspnoea
2.0
16.2
243
1381
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
16.2
227
1255
H19.3*M35.0
ICD-10 Finland
Keratoconjunctivitis sicca
34.0
15.8
20
6
H11.1
ICD-10 Finland
Conjunctival degenerations and deposits
86.4
15.6
17
*
XCK00
NOMESCO Finland
Perimetry
3.2
15.6
87
293
D07AD01
ATC
clobetasol; topical
2.2
15.5
167
822
M03BX02
ATC
tizanidine; oral
1.7
15.4
603
4680
J01AA07
ATC
tetracycline; systemic
2.2
15.3
169
840
D07AC01
ATC
betamethasone; topical
1.8
15.2
329
2124
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.1
15.1
189
995
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
6.4
15.0
39
63
M25.5
ICD-10 Finland
Pain in joint
1.9
14.9
290
1804
N03AX16
ATC
pregabalin; oral
1.9
14.8
241
1405
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
57.5
14.8
17
*
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
5.9
14.8
41
72
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.9
14.6
92
337
UJF32
NOMESCO Finland
Coloscopy
1.9
14.6
252
1500
J01DA01
ATC
[U] cefalexin; systemic
1.7
14.3
606
4758
J45
ICD-10 Finland
Asthma
2.6
14.2
111
462
R03AK07
ATC
formoterol and budesonide; inhalant
2.0
14.2
199
1095
R03BA05
ATC
fluticasone; inhalant
2.0
14.2
195
1063
A02BC02
ATC
pantoprazole; systemic
1.7
14.2
607
4774
G44.2
ICD-10 Finland
Tension-type headache
2.2
13.9
151
744
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
13.7
100
402
J01CA04
ATC
amoxicillin; systemic
1.8
13.7
810
6982
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
13.6
360
2457
J45.1
ICD-10 Finland
Nonallergic asthma
2.9
13.5
86
317
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
13.5
280
1769
J01FA09
ATC
clarithromycin; systemic
1.8
13.4
319
2108
ZXA10
NOMESCO Finland
Bilateral
2.0
13.2
193
1077
TCC10
NOMESCO Finland
Probing of lacrimal canaliculus/duct
12.4
13.1
23
19
N05BB01
ATC
hydroxyzine; systemic
3.0
13.1
79
280
D07BB04
ATC
hydrocortisone butyrate and antiseptics; topical
2.3
13.1
133
636
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.6
13.1
98
399
L71.8
ICD-10 Finland
Other rosacea
7.1
12.9
31
45
F03
ICPC
Eye discharge
2.9
12.8
78
281
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
12.6
343
2345
J02AC01
ATC
fluconazole; systemic
1.7
12.5
416
3012
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.4
12.5
114
515
R05
ICD-10 Finland
Cough
1.9
12.3
197
1133
S01BC05
ATC
ketorolac; ophthalmic
3.8
12.2
51
139
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.8
12.2
51
139
WX002
NOMESCO Finland
Sedation and analgesia
1.9
12.1
192
1101
R42
ICD-10 Finland
Dizziness and giddiness
1.9
12.1
209
1237
H57.1
ICD-10 Finland
Ocular pain
3.9
12.0
48
126
D07BA04
ATC
hydrocortisone and antiseptics; topical
2.3
12.0
111
507
T78.4
ICD-10 Finland
Allergy, unspecified
3.3
12.0
61
195
R21
ICPC
Throat symptom/complaint
1.9
11.8
208
1236
H11.0
ICD-10 Finland
Pterygium
65.7
11.6
13
*
J30.0
ICD-10 Finland
Vasomotor rhinitis
4.8
11.6
38
82
R53
ICD-10 Finland
Malaise and fatigue
1.9
11.6
196
1150
H11.3
ICD-10 Finland
Conjunctival haemorrhage
4.9
11.6
37
78
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
3.1
11.5
62
206
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.2
11.5
129
643
N06AX11
ATC
mirtazapine; oral
1.7
11.5
294
1965
J01AA04
ATC
lymecycline; systemic
2.1
11.5
137
700
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.8
11.5
218
1328
H11.4
ICD-10 Finland
Other conjunctival vascular disorders and cysts
121.3
11.4
12
*
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.8
11.3
204
1222
H02AB04
ATC
methylprednisolone; systemic
2.0
11.3
148
789
Z51.6
ICD-10 Finland
Desensitization to allergens
9.0
11.3
23
26
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
11.3
296
1991
N06AX16
ATC
venlafaxine; oral
2.1
11.2
138
717
J05AB01
ATC
aciclovir; systemic
1.8
11.1
210
1278
J01DA06
ATC
[U] cefuroxime; systemic
2.0
11.0
153
831
A02BA02
ATC
ranitidine; systemic
1.9
11.0
178
1027
A02BC03
ATC
lansoprazole; oral
1.7
10.9
264
1733
Z58.8
ICD-10 Finland
Other problems related to physical environment
43.8
10.9
13
*
L20
ICD-10 Finland
Atopic dermatitis
4.3
10.9
40
97
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
10.9
91
394
S01AA02
ATC
chlortetracycline; ophthalmic
12.1
10.9
19
16
R01AC02
ATC
levocabastine; nasal
4.6
10.7
36
80
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.7
10.7
74
289
CF2S4
NOMESCO Finland
Photography of conjunctiva
60.6
10.6
12
*
CG2T4
NOMESCO Finland
Topography assessment of cornea
11.4
10.6
19
17
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.0
10.4
60
209
J01MA02
ATC
ciprofloxacin; systemic
1.6
10.4
337
2394
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
4.6
10.3
35
79
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
10.3
223
1411
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
10.3
229
1464
D11AH02
ATC
pimecrolimus; topical
23.6
10.3
14
6
S01EE05
ATC
tafluprost; ophthalmic
3.9
10.2
41
109
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.2
10.2
104
497
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
10.1
499
3915
R51.80
ICD-10 Finland
Headache
1.9
10.0
151
847
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.9
10.0
165
956
D07CA01
ATC
hydrocortisone and antibiotics; topical
2.0
10.0
134
720
CBB30
NOMESCO Finland
Excision of lesion of eyelid
4.2
9.8
36
88
J02AC02
ATC
itraconazole; systemic
1.8
9.8
180
1079
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.6
9.8
294
2037
H10.8
ICD-10 Finland
Other conjunctivitis
10.8
9.8
18
17
E000006
ATC
NA
2.4
9.8
81
348
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.3
9.7
91
416
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.1
9.7
112
567
D06BX01
ATC
metronidazole; topical
2.1
9.6
109
545
S01ED01
ATC
timolol; ophthalmic
3.5
9.6
44
131
N02BE01
ATC
paracetamol; systemic, rectal
1.7
9.6
802
7099
F02
ICPC
Red eye
3.0
9.6
54
184
D07XC01
ATC
betamethasone, combinations; topical
2.1
9.5
110
555
H16.8
ICD-10 Finland
Other keratitis
30.3
9.4
12
*
L01
ICPC
Neck symptom/complaint
1.9
9.4
139
774
H16.4
ICD-10 Finland
Corneal neovascularization
+∞
9.4
9
*
P01AB01
ATC
metronidazole; oral, rectal
1.5
9.4
376
2799
N06AB04
ATC
citalopram; systemic
1.7
9.3
207
1316
D07CC01
ATC
betamethasone and antibiotics; topical
2.0
9.3
123
656
R96
ICPC
Asthma
2.3
9.2
86
394
R74
ICPC
Upper respiratory infection acute
1.6
9.2
280
1947
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.0
9.1
118
623
D02AX
ATC
Other emollients and protectives
3.3
9.1
45
142
J45.8
ICD-10 Finland
Mixed asthma
3.8
9.1
37
100
CG2S4
NOMESCO Finland
Photography of cornea
15.7
9.0
14
9
F01
ICPC
Eye pain
3.7
9.0
38
106
U02
ICPC
Urinary frequency/urgency
1.9
9.0
129
711
M79.6
ICD-10 Finland
Pain in limb
1.6
9.0
323
2334
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
9.0
94
456
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
9.0
262
1800
Z71.8
ICD-10 Finland
Other specified counselling
1.7
8.9
224
1474
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.4
8.9
42
128
S01AA12
ATC
tobramycin; ophthalmic
24.2
8.9
12
5
R03BA01
ATC
beclometasone; inhalant
1.9
8.9
133
742
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
3.8
8.8
36
98
XF400
NOMESCO Finland
ECG with 12 standard connections
1.8
8.8
150
877
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.1
8.8
99
496
M01AH05
ATC
etoricoxib; oral
1.5
8.7
538
4380
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.5
8.7
66
272
F71
ICPC
Conjunctivitis allergic
50.4
8.7
10
*
ZXC60
NOMESCO Finland
Application of heat
5.1
8.7
26
52
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.7
8.7
207
1345
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
8.6
124
685
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
8.3
8.6
18
22
D31.0
ICD-10 Finland
Benign neoplasm: Conjunctiva
11.7
8.6
15
13
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
8.6
124
686
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
2.2
8.6
86
407
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.6
406
3121
L04AX01
ATC
azathioprine; systemic
2.7
8.5
55
208
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.3
8.5
76
343
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
3.2
8.4
43
140
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
8.4
203
1323
CGE55
NOMESCO Finland
Excision of pterygium with transplanation of conjunctiva
+∞
8.3
8
*
J01FF01
ATC
clindamycin; systemic
1.6
8.3
242
1654
A07AA02
ATC
nystatin; oral
2.5
8.3
63
260
R03AK08
ATC
formoterol and beclometasone; inhalant
3.2
8.3
42
136
A01AB04
ATC
amphotericin B; local oral
2.7
8.2
53
200
M54.5
ICD-10 Finland
Low back pain
1.5
8.2
295
2125
N06AX21
ATC
duloxetine; oral
2.0
8.2
111
596
S18
ICPC
Laceration/cut
1.5
8.2
364
2750
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.7
8.2
55
211
H00.1
ICD-10 Finland
Chalazion
3.1
8.1
43
144
J30.1
ICD-10 Finland
Allergic rhinitis due to pollen
33.6
8.1
10
*
H01.1
ICD-10 Finland
Noninfectious dermatoses of eyelid
9.0
8.1
16
18
N05CF01
ATC
zopiclone; oral
1.6
8.0
275
1956
A11
ICPC
Chest pain NOS
2.4
8.0
67
292
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.0
8.0
43
146
M02AA07
ATC
piroxicam; topical
1.5
7.9
312
2291
R03BA08
ATC
ciclesonide; inhalant
2.2
7.9
84
407
R05
ICPC
Cough
1.6
7.9
207
1372
L03
ICPC
Low back symptom/complaint
1.6
7.9
220
1486
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.9
7.9
46
163
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
3.3
7.8
37
114
F45.8
ICD-10 Finland
Other somatoform disorders
2.3
7.8
72
330
D02AE01
ATC
carbamide; topical
2.3
7.8
67
297
E000007
ATC
NA
2.6
7.8
55
220
S01EC04
ATC
brinzolamide; ophthalmic
3.3
7.8
38
120
H15.1
ICD-10 Finland
Episcleritis
5.1
7.7
23
46
F51.0
ICD-10 Finland
Nonorganic insomnia
1.9
7.7
121
688
WX110
NOMESCO Finland
Local anesthesy
1.5
7.7
646
5539
D11AX15
ATC
[U] pimecrolimus; topical
45.3
7.7
9
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
7.7
507
4143
H10.2
ICD-10 Finland
Other acute conjunctivitis
5.6
7.7
21
38
S29
ICPC
Skin symptom/complaint other
1.8
7.7
149
908
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
7.6
99
523
6918B
ICD-9 Finland
Atopic dermatitis and related conditions, Other atopic dermatitis and related conditions[ECZEMA ATOPICUM]
6.8
7.6
18
27
69100
ICD-8 Finland
Infantile eczema and related conditions, Eczema atopicum. Prurigo Besnier. Eczema pruriginosum allergicum
5.2
7.6
22
43
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
7.4
147
901
R06.5
ICD-10 Finland
Mouth breathing
2.1
7.4
81
400
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.8
7.4
134
799
N03AX12
ATC
gabapentin; oral
1.8
7.4
141
854
KMAK
NOMESCO Finland
NA
1.4
7.3
476
3864
A01AB09
ATC
miconazole; local oral
2.0
7.3
86
439
114
Kela drug reimbursment
Glaucoma
2.1
7.3
77
374
R03AC13
ATC
formoterol; inhalant
2.6
7.3
51
204
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
7.2
162
1031
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
7.2
238
1672
N95
ICPC
Tension headache
20.2
7.1
10
5
H57.9
ICD-10 Finland
Disorder of eye and adnexa, unspecified
6.6
7.1
17
26
S01ED02
ATC
betaxolol; ophthalmic
8.0
7.1
15
19
CD2S4
NOMESCO Finland
Photography of eye
8.0
7.1
15
19
K04
ICPC
Palpitations/awareness of heart
2.5
7.1
54
226
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
2.8
7.1
43
158
E000003
ATC
NA
2.6
7.0
49
194
R50.9
ICD-10 Finland
Fever, unspecified
1.7
7.0
135
819
R49.01
ICD-10 Finland
Functional dysphonia
3.3
7.0
33
102
H19.1*B00.5
ICD-10 Finland
Herpesviral keratoconjunctivitis
7.0
7.0
16
23
R03BB01
ATC
ipratropium bromide; inhalant
3.1
7.0
36
119
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
7.0
128
764
L04
ICPC
Chest symptom/complaint
2.4
7.0
55
234
R03BB04
ATC
tiotropium bromide; inhalant
2.0
6.9
80
407
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
7.6
6.9
15
20
R01AD11
ATC
triamcinolone; nasal
2.0
6.9
84
436
N06AB03
ATC
fluoxetine; oral
1.8
6.9
119
698
D01
ICPC
Abdominal pain/cramps general
1.9
6.9
107
607
J30.4
ICD-10 Finland
Allergic rhinitis, unspecified
2.9
6.9
40
142
R02
ICPC
Shortness of breath/dyspnoea
1.9
6.9
101
562
H40.9
ICD-10 Finland
Glaucoma, unspecified
4.9
6.9
21
44
S01ED51
ATC
timolol, combinations; ophthalmic
2.2
6.9
65
302
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
6.8
74
363
N05BA04
ATC
oxazepam; oral
1.6
6.8
215
1491
UKC02
NOMESCO Finland
Cystoscopy
1.8
6.8
113
656
R35
ICD-10 Finland
Polyuria
2.4
6.8
54
231
R05FB02
ATC
cough suppressants and expectorants
1.5
6.8
325
2473
M03BC01
ATC
orphenadrine (citrate); systemic
1.6
6.8
216
1504
A01
ICPC
Pain general/multiple sites
2.1
6.7
74
368
J01DC02
ATC
cefuroxime; systemic
2.3
6.7
60
273
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.2
6.7
67
320
M48.0
ICD-10 Finland
Spinal stenosis
1.9
6.7
103
584
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.0
6.6
35
118
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
3.6
6.6
28
80
H18.8
ICD-10 Finland
Other specified disorders of cornea
7.9
6.6
14
18
CB9S4
NOMESCO Finland
Photography of eyelids and eyebrows
12.3
6.6
11
9
M01AE02
ATC
naproxen; oral, rectal
1.4
6.6
519
4337
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.1
6.6
73
366
R07.0
ICD-10 Finland
Pain in throat
2.2
6.5
61
283
A04
ICPC
Weakness/tiredness general
1.8
6.5
114
675
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.6
6.5
205
1424
S01CA03
ATC
hydrocortisone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
6.2
6.5
16
26
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.3
6.5
55
244
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.5
84
445
R13
ICD-10 Finland
Dysphagia
2.3
6.4
57
256
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.3
6.4
57
256
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
6.4
101
574
H02.0
ICD-10 Finland
Entropion and trichiasis of eyelid
4.1
6.4
23
57
K59.0
ICD-10 Finland
Constipation
2.4
6.4
54
236
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.6
6.4
43
169
L04AA06
ATC
mycophenolic acid; systemic
3.8
6.4
25
67
K07.60
ICD-10 Finland
Snapping jaw
2.3
6.4
54
238
S21
ICPC
Skin texture symptom/complaint
1.8
6.3
109
638
H02.1
ICD-10 Finland
Ectropion of eyelid
6.6
6.3
15
23
A92
ICPC
Allergy/allergic reaction NOS
3.3
6.3
30
94
A46
ICD-10 Finland
Erysipelas
1.8
6.3
107
622
L08.8
ICD-10 Finland
Other specified local infections of skin and subcutaneous tissue
3.3
6.3
29
89
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.9
6.3
91
505
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
6.3
360
2831
CFD10
NOMESCO Finland
Repair of conjunctiva
+∞
6.3
6
*
H03.1*B08.1
ICD-10 Finland
Involvement of eyelid in molluscum contagiosum
+∞
6.3
6
*
R03CC02
ATC
salbutamol; systemic
2.2
6.2
61
288
F13
ICPC
Eye sensation abnormal
3.1
6.2
31
101
WX140
NOMESCO Finland
Parabulbar anesthesy
2.7
6.2
38
142
H01
ICPC
Ear pain/earache
1.8
6.2
106
621
R4120
NOMESCO Finland
Occupational therapy
2.1
6.2
65
316
H02.3
ICD-10 Finland
Blepharochalasis
2.2
6.2
58
269
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
6.3
6.2
15
24
R01AC01
ATC
cromoglicic acid; nasal
2.8
6.2
37
136
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
6.2
361
2847
R06.2
ICD-10 Finland
Wheezing
2.5
6.1
45
186
H40.0
ICD-10 Finland
Glaucoma suspect
2.1
6.1
67
331
M01AG02
ATC
tolfenamic acid; oral, rectal
1.6
6.1
147
949
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
1.9
6.1
91
506
K30
ICD-10 Finland
Functional dyspepsia
1.8
6.1
95
539
L13
ICPC
Hip symptom/complaint
1.7
6.1
133
835
F43.8
ICD-10 Finland
Other reactions to severe stress
3.6
6.1
25
70
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
4.1
6.1
22
55
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.6
6.1
43
172
S01AA13
ATC
fusidic acid; ophthalmic
3.0
6.1
32
109
D18
ICPC
Change in faeces/bowel movements
3.6
6.0
25
71
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.2
6.0
57
266
Z50.1
ICD-10 Finland
Other physical therapy
2.4
6.0
49
213

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
258
1010
3.01
47.95
2.2
1.6
—
—
—
0
0
680
4625
2.18
34.83
7.8
6.0
0.6
0.6
e9/l
0.43
592
4028
698
4801
2.19
34.67
8.2
6.3
0.2
0.2
e9/l
1.28
619
4248
681
4644
2.18
34.52
7.8
6.0
0.0
0.0
e9/l
1.47
593
4047
690
4760
2.16
33.54
7.8
6.0
2.0
2.0
e9/l
0.03
609
4231
741
5399
2.08
29.29
10.4
9.3
4.0
4.0
e9/l
0.16
651
4735
386
2236
2.10
28.65
4.4
3.8
94.3
92.7
%
0.59
379
2174
256
1260
2.33
28.49
1.5
1.3
525.7
518.9
titre
0.02
63
261
404
2389
2.08
28.31
7.8
6.8
—
—
—
0
0
362
2096
2.07
26.53
4.5
3.7
—
—
—
0
0
485
3118
1.97
26.44
4.6
3.7
78.0
98.2
e6/l
0.24
332
2167
479
3102
1.95
25.25
7.6
6.1
—
—
—
0
0
546
3717
1.91
24.53
5.0
4.7
36.2
35.9
g/l
0.93
507
3474
284
1549
2.11
24.08
2.7
2.9
2.4
2.5
mmol/l
1.14
230
1376
599
4224
1.89
23.93
7.9
6.2
0.7
0.7
%
2.34
574
3950
613
4362
1.89
23.73
7.9
6.1
2.9
2.9
%
0.25
588
4075
622
4450
1.89
23.64
7.7
6.0
56.4
56.3
%
0.02
598
4176
856
6819
2.06
23.42
5.3
4.1
11.0
11.7
mm/h
0.89
818
6309
613
4382
1.87
23.19
8.1
6.4
8.4
8.4
%
0.12
589
4118
381
2347
1.94
22.77
4.1
3.0
—
—
—
0
0
264
1431
2.10
22.59
3.3
2.7
0.7
1.2
e6/l
2.73
149
815
624
4510
1.86
22.54
7.9
6.2
28.6
29.0
%
0.34
600
4218
100
350
3.04
21.89
1.3
1.2
0.2
1.2
u/ml
—
9
33
323
1926
1.95
20.96
1.6
1.5
2.3
2.3
g/l
0.02
185
1168
377
2378
1.88
20.55
4.1
3.1
0.2
0.5
e6/l
2.05
294
1792
564
4032
1.80
20.34
7.6
6.0
1.2
1.2
mmol/l
0.21
528
3651
452
3035
1.82
20.03
3.5
3.4
2.4
2.4
mmol/l
0.08
391
2675
497
3445
1.79
19.70
2.2
1.9
99.0
96.0
pmol/l
0.74
266
1770
401
2608
1.83
19.64
2.4
2.1
137.1
230.6
u/l
1.66
379
2461
141
623
2.44
19.56
1.6
1.2
451.3
205.5
u/ml
1.14
132
570
204
1056
2.14
19.43
1.9
1.5
—
—
—
0
0
759
5992
1.81
18.93
5.8
4.3
12.9
3011.7
e6/l
—
10
83
539
3877
1.75
18.40
2.7
2.4
79.7
76.7
nmol/l
1.55
501
3506
394
2597
1.79
18.16
5.0
3.8
7.4
7.4
ph
0.79
42
500
348
2217
1.82
17.92
2.5
2.6
1906.4
5602.9
umol/l
1.32
304
1934
515
3701
1.72
17.29
2.4
2.0
—
—
—
0
0
390
2604
1.76
16.95
4.1
3.2
42.2
75.8
e6/l
0.60
304
2001
138
649
2.28
16.54
1.7
1.4
—
—
—
0
0
291
1797
1.83
16.36
3.1
2.5
4.6
6.9
e6/l
2.60
263
1580
587
4438
1.67
15.79
8.4
6.6
1.2
1.2
mmol/l
0.25
537
3751
23
32
7.32
15.71
1.5
1.5
—
—
—
0
0
144
707
2.19
15.51
3.3
2.8
9.7
10.2
g/l
1.00
139
650
169
883
2.07
15.50
1.9
1.5
—
—
—
0
0
546
4088
1.65
14.97
3.1
2.7
124.5
111.4
ug/l
0.35
521
3790
57
182
3.25
14.56
1.1
1.1
5.0
6.2
u/ml
0.29
47
97
154
804
2.06
14.10
2.7
2.2
122.8
38.6
u/l
0.47
138
673
226
1346
1.85
14.05
3.5
2.9
2.0
3.0
e6/l
0.96
111
737
549
4159
1.62
14.05
9.2
9.2
0.0
0.0
e9/l
0.26
437
3412
867
7382
1.75
13.89
5.0
4.0
14.6
14.7
pmol/l
0.74
816
6742
833
7037
1.70
13.47
8.4
7.2
80.9
80.2
u/l
0.14
798
6614
1036
9380
2.27
13.26
18.1
12.8
21.8
22.3
mg/l
0.18
832
7257
116
564
2.18
12.75
1.8
1.8
1.0
1.3
g/l
1.50
108
522
258
1645
1.74
12.61
1.4
1.3
18.4
31.4
iu/ml
2.31
77
534
123
615
2.12
12.59
2.4
2.4
36.3
24.1
au/ml
—
8
37
974
8661
1.91
12.56
6.1
4.8
1.8
1.9
mu/l
2.08
917
7963
928
8134
1.79
12.50
23.8
16.6
332.4
332.4
g/l
0.10
923
8071
145
776
2.00
12.35
1.2
1.2
—
—
—
0
0
83
355
2.44
12.29
1.6
1.2
—
—
—
0
0
51
175
3.00
11.58
1.1
1.1
2.7
2.4
u/ml
0.06
38
86
580
4580
1.55
11.57
4.6
3.7
0.0
0.0
estimate
0.80
64
815
323
2236
1.62
11.39
1.4
1.3
1.2
1.6
u/ml
0.30
74
592
81
356
2.37
11.31
2.0
1.5
18.9
8.9
u/ml
—
5
8
570
4504
1.54
11.20
4.6
3.6
0.0
0.0
estimate
0.00
64
834
313
2159
1.62
11.17
2.3
2.2
—
—
—
0
0
573
4535
1.54
11.16
6.1
4.9
0.0
0.0
estimate
0.50
66
838
260
1716
1.67
11.03
3.2
2.8
533.8
550.9
mosm/kgh2o
0.59
228
1457
55
204
2.78
10.86
1.1
1.1
2.8
2.9
u/ml
0.01
38
95
200
1235
1.75
10.81
2.5
2.4
116.3
127.8
ug/g
0.16
147
977
179
1075
1.79
10.63
1.9
1.5
—
—
—
0
0
241
1574
1.68
10.60
1.4
1.3
4.1
13.9
u/ml
3.40
68
627
129
700
1.95
10.52
4.8
3.5
—
—
—
0
0
748
6316
1.55
10.50
5.4
4.2
—
—
—
0
0
199
1239
1.74
10.42
1.9
2.0
—
—
—
0
0
48
176
2.80
9.71
1.1
1.1
3.2
3.0
u/ml
—
10
53
582
4724
1.48
9.40
5.9
6.1
11.3
11.5
umol/l
0.13
561
4482
21
45
4.74
9.32
2.0
3.2
946.2
900.1
u/ml
0.04
21
45
381
2846
1.51
9.25
2.5
2.2
—
—
—
0
0
315
2259
1.55
9.25
5.0
4.1
—
—
—
0
0
290
2042
1.57
9.23
1.9
1.8
1.0
1.1
mg/l
0.32
232
1552
253
1726
1.60
9.22
2.2
1.8
—
—
—
0
0
217
1430
1.64
9.10
1.8
1.6
—
—
—
0
0
213
1400
1.64
9.02
4.2
3.9
0.8
0.8
mmol/l
0.05
202
1308
1028
9509
1.91
8.86
19.6
14.4
139.5
139.7
mmol/l
1.35
1011
9264
893
7970
1.58
8.68
20.8
15.7
13.6
13.6
%
0.03
882
7792
1029
9541
1.89
8.51
19.9
14.5
3.9
4.0
mmol/l
2.30
1008
9279
99
538
1.92
8.03
1.9
2.5
—
—
—
0
0
54
233
2.38
7.91
1.3
1.2
3.0
2.8
u/ml
—
7
23
188
1237
1.62
7.86
1.3
1.2
—
—
—
0
0
1050
9842
1.96
7.77
14.3
12.0
—
—
—
0
0
118
686
1.80
7.75
2.7
2.3
4.0
7.2
ug/l
3.37
100
611
116
682
1.78
7.34
1.6
1.4
—
—
—
0
0
199
1349
1.58
7.32
2.2
2.3
14.8
13.3
umol/l
1.83
188
1242
296
2187
1.48
7.29
2.3
2.2
2.7
3.0
mg/l
1.87
267
1871
108
629
1.79
7.06
1.3
1.2
—
—
—
0
0
273
1997
1.48
7.04
5.2
4.0
1.0
1.0
kg/l
0.59
32
305
39
153
2.60
6.99
1.4
1.2
—
—
—
0
0
159
1038
1.62
6.83
2.8
3.0
6.7
8.6
umol/l
0.88
141
898
214
1497
1.53
6.81
1.7
1.7
1165.1
1214.2
nmol/l
0.37
172
1127
142
903
1.65
6.77
2.4
2.0
379.9
367.7
nmol/l
0.30
130
835
59
283
2.14
6.77
1.3
1.2
—
—
—
0
0
191
1317
1.54
6.48
2.4
2.2
28.4
29.6
s
3.35
184
1279
26
86
3.07
6.37
1.7
1.3
—
—
—
0
0
225
1617
1.49
6.26
3.7
3.6
214.7
458.8
ng/l
1.45
164
1186
264
1959
1.45
6.24
1.6
1.5
22.0
21.0
nmol/l
0.50
239
1665
113
695
1.70
6.11
3.8
4.0
74.3
77.7
ng/l
0.24
105
616
23
73
3.20
6.04
3.5
1.9
679.1
747.9
e6/l
—
10
22
1050
9953
1.79
5.87
13.1
9.9
26.9
26.0
u/l
0.60
1029
9620
53
260
2.09
5.77
3.9
3.2
—
—
—
0
0
948
8783
1.50
5.72
20.2
13.8
39.8
39.7
%
0.26
762
6500
303
2344
1.40
5.62
2.9
3.1
1080.4
1078.6
ng/l
0.00
256
1953
175
1220
1.51
5.61
2.3
2.3
2.4
2.4
g/l
0.03
169
1133
715
6340
1.35
5.39
4.4
3.5
—
—
—
0
0
164
1140
1.51
5.33
2.5
2.4
24.9
23.1
%
0.80
153
975
47
228
2.11
5.29
2.5
3.9
63.9
75.3
mg/l
0.14
40
178
47
228
2.11
5.29
2.5
3.9
27.2
44.5
mg/l
0.66
40
178
26
96
2.75
5.29
3.3
2.5
1.3
1.1
e9/l
0.25
13
61
24
85
2.86
5.27
2.2
2.3
35.8
39.7
%
—
6
6
27
103
2.66
5.17
1.1
1.5
249.4
334.9
pmol/l
0.98
21
82
603
5236
1.33
5.13
5.7
4.6
6.4
6.6
mmol/l
1.67
560
4881
137
926
1.55
5.06
1.7
1.6
—
—
—
0
0
82
490
1.73
4.95
8.6
9.1
94.8
94.3
%
0.38
82
485
20
67
3.02
4.84
1.2
1.2
—
—
—
0
0
85
518
1.69
4.79
1.4
1.2
—
—
—
0
0
165
1178
1.47
4.69
7.6
5.5
1.1
1.1
mmol/l
0.04
156
1090
123
827
1.55
4.66
2.1
2.5
0.2
0.2
g/l
0.68
111
782
35
164
2.17
4.34
1.4
1.7
—
—
—
0
0
78
478
1.68
4.32
7.8
5.3
23.7
24.0
mmol/l
0.39
71
437
39
193
2.06
4.22
2.2
1.8
—
—
—
0
0
109
732
1.54
4.16
9.9
8.3
—
—
—
0
0
125
865
1.50
4.15
2.4
4.1
12.1
27.2
ug/l
0.64
94
703
36
176
2.08
4.04
2.5
4.3
—
—
—
0
0
133
938
1.47
4.03
3.2
2.8
1.8
1.8
%
0.04
124
844
157
1152
1.42
3.86
1.3
1.3
—
—
—
0
0
23
96
2.42
3.74
1.3
1.7
—
—
—
0
0
95
635
1.54
3.72
2.4
3.0
166.2
184.8
ng/l
0.23
83
582
48
268
1.83
3.70
1.3
1.2
—
—
—
0
0
27
123
2.22
3.63
1.2
1.4
—
0.6
—
0
10
1087
10551
1.81
3.61
26.5
18.9
258.1
256.5
e9/l
0.31
1066
10282
56
332
1.72
3.55
1.4
1.3
244.5
236.2
miu/ml
0.06
27
161
18
69
2.63
3.48
5.5
3.7
—
—
—
0
0
1087
10559
1.79
3.48
26.4
18.8
30.3
30.2
pg
2.93
1078
10416
1087
10560
1.79
3.46
26.5
18.9
4.5
4.5
e12/l
0.85
1061
10270
1087
10561
1.79
3.45
26.5
18.9
6.7
6.7
e9/l
0.37
1064
10265
946
8950
1.35
3.43
5.2
4.3
5.8
5.9
mmol/l
1.42
892
8180
30
147
2.07
3.38
1.0
1.0
—
—
—
0
0
1087
10567
1.77
3.35
26.6
19.0
134.8
134.9
g/l
0.06
1078
10424
125
904
1.43
3.34
7.3
7.9
1.2
1.2
mmol/l
0.07
100
714
24
108
2.25
3.33
1.3
1.4
—
—
nmol/l
—
0
0
1086
10556
1.76
3.33
26.4
18.8
91.0
90.5
fl
2.95
1077
10414
125
908
1.42
3.26
7.3
7.9
12.9
12.6
kpa
0.22
118
872
125
908
1.42
3.26
7.3
7.9
5.0
5.1
kpa
0.55
119
872
18
72
2.52
3.22
1.0
1.3
0.1
1.0
u/ml
—
9
26
7
11
6.40
3.19
3.7
4.5
—
—
—
0
0
133
984
1.40
3.14
27.1
22.5
1.2
1.3
inr
—
10
136
137
1022
1.39
3.08
1.5
1.5
—
—
—
0
0
58
362
1.63
3.07
1.7
1.7
—
—
—
0
0
101
715
1.45
3.04
1.2
1.2
79.7
134.3
iu/ml
1.36
39
290
68
444
1.57
3.00
2.8
2.3
—
—
—
0
0
76
509
1.53
3.00
1.1
1.2
—
95.8
—
0
13
23
107
2.17
2.98
1.2
1.2
—
—
—
0
0
135
1012
1.38
2.95
1.3
1.3
—
—
—
0
0
379
3266
1.24
2.91
4.2
3.4
56.3
46.2
ng/l
0.13
238
2127
45
267
1.71
2.89
1.3
1.5
292.1
295.0
ug/g
0.03
29
161
61
392
1.59
2.89
1.1
1.1
—
—
—
0
0
21
97
2.19
2.78
5.3
3.5
—
—
—
0
0
29
153
1.92
2.72
1.1
1.4
58.1
67.4
mmol/l
0.64
21
127
71
480
1.51
2.70
5.3
4.7
—
—
—
0
0
6
10
6.03
2.70
1.0
1.3
—
—
—
0
0
484
4308
1.22
2.67
3.9
3.9
—
—
—
0
0
12
43
2.81
2.65
1.2
2.1
—
—
—
0
0
18
80
2.27
2.61
2.7
2.6
10.9
14.2
%
0.46
13
46
17
74
2.32
2.58
1.6
1.2
83.0
1.9
u/ml
0.88
11
30
20
94
2.15
2.55
1.2
1.1
—
—
—
0
0
331
2845
1.23
2.55
2.9
2.4
59.3
55.5
u/l
1.01
311
2625
85
605
1.44
2.52
2.5
3.2
4.2
4.6
pmol/l
4.61
78
524
34
195
1.77
2.49
1.9
1.5
—
—
—
0
0
7
16
4.40
2.47
2.3
1.7
—
—
—
0
0
23
116
2.00
2.47
1.0
1.4
—
—
—
0
0
25
131
1.93
2.42
1.0
1.1
6.8
5.3
u/ml
0.15
15
56
24
124
1.96
2.41
1.3
3.2
5.4
8.1
umol/l
0.58
15
86
37
220
1.70
2.40
2.2
1.6
3.8
3.7
mmol/l
0.14
37
209
36
213
1.71
2.38
2.1
1.8
505.2
1044.8
e6/l
0.36
24
173
48
307
1.59
2.36
2.4
3.1
14750.1
982.6
u/ml
0.46
37
269
42
260
1.64
2.35
2.6
1.8
3.2
5.2
iu/l
0.67
16
90
21
105
2.02
2.32
2.9
2.0
—
—
—
0
0
21
105
2.02
2.32
1.7
1.4
288.6
279.4
mosm/kgh2o
1.26
16
78
54
357
1.54
2.31
1.1
1.1
—
—
—
0
0
51
334
1.55
2.28
1.9
1.7
1.6
1.5
g/l
0.10
46
294
19
92
2.08
2.28
1.4
1.3
—
—
—
0
0
34
202
1.70
2.23
2.5
3.4
22.8
27.9
u/ml
0.31
34
196
17
80
2.14
2.19
1.3
1.1
—
—
—
0
0
11
42
2.63
2.19
1.8
1.9
6.5
6.0
nmol/l
0.03
11
33
282
2420
1.22
2.18
1.7
1.7
1.4
1.4
mmol/l
0.32
259
2036
283
2430
1.22
2.17
5.7
4.0
0.0
0.0
estimate
1.34
61
829
20
101
2.00
2.16
2.2
3.3
—
—
—
0
0
35
213
1.66
2.12
2.1
1.7
14.7
14.1
e6/l
0.02
23
171
22
116
1.91
2.12
1.0
1.1
0.3
0.5
u/ml
—
9
35
27
153
1.78
2.09
1.0
1.1
—
—
—
0
0
0
56
0.00
2.06
0.0
1.8
—
—
—
0
0
296
3386
0.83
2.05
2.4
2.7
—
—
—
0
0
917
8784
1.23
2.04
4.4
3.8
1.4
1.3
mmol/l
1.81
867
8100
12
50
2.42
2.03
1.2
1.2
—
—
—
0
0
381
3387
1.19
2.00
8.1
8.2
1.2
1.2
inr
0.12
81
997
15
70
2.16
1.99
1.3
1.4
1851.0
2077.9
e6/l
—
9
49
73
532
1.40
1.95
1.6
1.7
—
—
—
0
0
84
627
1.37
1.95
5.0
4.6
7.4
7.4
ph
—
6
71
70
508
1.40
1.92
2.5
2.3
12.0
12.5
nmol/l
0.19
63
452
965
9310
1.25
1.92
5.5
4.7
2.8
2.8
mmol/l
0.62
917
8616
94
716
1.34
1.92
6.6
4.3
4.4
4.7
kpa
0.68
89
690
11
239
0.45
1.90
4.6
4.5
—
—
—
0
0
30
181
1.68
1.90
1.9
1.5
127.8
116.0
u/ml
—
6
30
14
65
2.17
1.88
1.3
1.4
225522.9
127324.4
e6/l
—
7
40
19
100
1.92
1.86
2.8
2.6
—
—
—
0
0
11
46
2.40
1.85
1.9
2.2
—
—
—
0
0
10
40
2.51
1.84
1.1
1.3
122.5
142.9
nmol/l
—
10
40
14
66
2.14
1.82
1.2
1.4
—
—
—
0
0
40
263
1.54
1.81
3.0
2.5
—
—
—
0
0
12
53
2.28
1.81
4.5
2.2
—
—
—
0
0
945
9110
1.23
1.81
4.7
4.2
1.5
1.5
mmol/l
0.03
900
8426
246
2121
1.20
1.80
5.1
4.7
—
—
—
0
0
27
161
1.69
1.79
1.2
1.2
—
—
—
0
0
89
681
1.33
1.78
2.6
2.8
73.2
71.8
e9/l
0.13
64
523
22
124
1.79
1.76
2.0
1.5
—
—
—
0
0
24
139
1.74
1.76
1.0
1.1
8.8
4.4
u/ml
0.43
13
59
107
842
1.30
1.76
6.6
4.5
5.9
5.8
kpa
0.64
102
814
15
74
2.04
1.75
1.3
1.2
—
—
—
0
0
16
81
1.99
1.75
1.1
1.0
—
—
—
0
0
6
18
3.35
1.75
1.8
2.8
—
—
—
0
0
6
18
3.35
1.75
4.0
1.3
—
—
—
0
0
9
36
2.51
1.74
1.6
1.8
—
—
—
0
0
43
291
1.50
1.72
2.8
3.9
1.1
1.4
mmol/l
1.93
43
284
948
9159
1.22
1.67
4.9
4.2
4.7
4.7
mmol/l
0.25
906
8530
6
19
3.17
1.66
1.7
2.5
21.6
15.6
umol/l
—
6
19
8
31
2.59
1.66
1.3
1.8
—
—
—
0
0
59
800
0.72
1.65
6.4
3.6
—
—
—
0
0
15
76
1.99
1.64
1.3
1.4
—
—
—
0
0
52
719
0.71
1.64
4.9
4.2
0.6
0.5
%
0.06
20
162
21
120
1.76
1.63
1.6
1.6
—
—
—
0
0
21
120
1.76
1.63
1.6
1.6
—
—
—
0
0
21
120
1.76
1.63
1.6
1.6
—
—
—
0
0
21
120
1.76
1.63
1.6
1.6
—
—
—
0
0
5
14
3.58
1.61
1.2
1.1
—
—
—
0
0
24
144
1.68
1.58
1.7
1.6
—
—
—
0
0
32
207
1.56
1.58
1.4
1.5
—
—
—
0
0
46
322
1.45
1.58
3.5
4.6
—
—
—
0
0
105
839
1.28
1.56
6.7
4.5
1.5
1.9
mmol/l
0.38
86
658
46
323
1.44
1.55
2.8
4.1
0.4
0.2
g/l
0.69
18
143
13
64
2.04
1.54
12.7
7.9
9.6
11.5
%
0.82
13
64
10
44
2.28
1.53
1.5
1.2
—
—
—
0
0
5
15
3.34
1.52
1.4
1.0
5.0
5.7
mg/g
—
5
15
5
15
3.34
1.52
1.4
1.0
—
—
—
0
0
46
325
1.43
1.51
1.5
1.4
—
—
—
0
0
6
21
2.87
1.50
1.2
1.1
—
—
—
0
0
6
21
2.87
1.50
1.3
1.1
—
—
—
0
0
29
188
1.56
1.44
1.9
1.7
9813.3
16962.0
e6/l
0.43
20
143
9
39
2.32
1.43
1.4
1.8
—
—
—
0
0
9
40
2.26
1.40
1.6
1.2
—
—
—
0
0
11
53
2.09
1.38
1.3
1.2
—
—
—
0
0
30
199
1.52
1.36
1.4
1.4
—
—
—
0
0
23
143
1.62
1.36
1.6
1.8
—
—
—
0
0
30
200
1.51
1.33
1.4
1.4
—
—
—
0
0
53
702
0.74
1.32
4.6
4.4
0.0
0.6
%
0.64
21
171
869
8381
1.16
1.32
6.4
5.4
38.8
39.5
mmol/mol
1.38
825
7813
67
518
1.31
1.30
1.4
1.4
32.2
28.8
iu/l
0.30
56
429
57
745
0.75
1.30
4.9
4.4
0.3
0.1
%
0.40
23
207
52
388
1.36
1.28
2.0
1.8
—
—
—
0
0
10
48
2.09
1.28
1.0
1.0
—
—
—
0
0
61
786
0.76
1.26
4.9
4.3
0.8
1.0
%
0.22
24
227
8
36
2.23
1.24
1.0
1.1
146.5
197.8
iu/ml
—
8
36
11
56
1.97
1.22
3.9
7.4
—
—
—
0
0
67
524
1.30
1.21
3.0
5.7
—
—
—
0
0
75
597
1.27
1.19
1.4
1.4
—
—
—
0
0
8
38
2.11
1.18
4.9
2.9
—
—
—
0
0
209
1844
1.16
1.18
1.5
1.7
436.7
30313333.8
pmol/l
2.04
176
1534
23
150
1.54
1.15
1.1
1.2
74.1
20.2
u/l
0.80
18
129
79
637
1.26
1.14
2.3
2.9
4.3
3.9
e9/l
0.57
63
514
27
183
1.49
1.14
1.4
1.2
—
—
—
0
0
7
30
2.34
1.12
2.7
2.6
—
—
—
0
0
10
51
1.97
1.11
1.0
1.0
—
—
—
0
0
17
104
1.64
1.09
3.2
4.6
17.2
104.7
u/ml
—
7
30
58
732
0.78
1.05
6.1
3.7
1.2
1.2
mmol/l
0.71
52
632
14
82
1.72
1.05
1.1
1.1
—
—
—
0
0
31
221
1.41
1.03
1.1
1.1
—
—
—
0
0
20
130
1.55
1.03
1.7
1.4
—
—
—
0
0
5
107
0.46
1.01
1.2
2.5
—
—
—
0
0
305
2792
1.13
1.01
3.7
3.0
—
—
—
0
0
25
172
1.46
1.00
10.4
4.8
—
—
—
0
0
16
99
1.63
1.00
2.4
2.3
—
—
—
0
0
89
741
1.22
0.99
10.8
7.6
8.5
8.4
mmol/l
0.04
82
703
11
61
1.81
0.98
1.4
1.4
—
—
—
0
0
227
2511
0.88
0.97
3.9
3.2
—
—
—
0
0
7
36
1.95
0.97
2.3
1.5
—
—
—
0
0
16
100
1.61
0.97
7.4
6.0
8.3
6.9
mmol/l
—
9
82
6
119
0.50
0.94
1.7
2.7
12.7
13.2
%
—
6
119
12
70
1.72
0.92
1.2
1.6
—
—
—
0
0
34
452
0.74
0.92
3.1
3.5
—
—
—
0
0
6
28
2.15
0.91
6.0
3.8
—
—
—
0
0
14
86
1.64
0.91
1.3
1.2
—
—
—
0
0
95
804
1.20
0.91
1.5
1.4
—
—
—
0
0
6
29
2.07
0.89
1.0
1.1
—
—
—
0
0
10
169
0.59
0.88
1.0
1.1
—
125.2
—
0
45
8
43
1.87
0.87
5.0
2.7
—
—
—
0
0
99
845
1.19
0.87
5.4
3.7
—
—
—
0
0
6
30
2.01
0.87
1.0
1.3
—
—
—
0
0
119
1042
1.16
0.78
1.8
1.7
—
—
—
0
0
12
74
1.63
0.78
1.6
2.5
—
—
—
0
0
24
174
1.39
0.77
1.1
1.1
—
—
—
0
0
25
183
1.37
0.76
4.8
3.4
4.1
4.2
e9/l
0.04
25
183
24
175
1.38
0.75
1.1
1.1
—
—
—
0
0
5
24
2.09
0.74
1.2
1.0
—
—
—
0
0
5
25
2.00
0.72
1.0
1.0
—
—
—
0
0
16
230
0.69
0.72
3.6
3.6
25.1
24.9
mmol/l
0.08
16
203
20
142
1.42
0.72
1.5
1.2
4.2
5.5
u/ml
—
9
62
17
117
1.46
0.72
1.2
1.1
—
—
—
0
0
114
1005
1.15
0.70
3.5
2.8
0.6
0.8
ug/l
2.75
82
619
26
196
1.33
0.68
1.5
2.2
143.6
128.7
g/l
0.81
11
148
25
190
1.32
0.63
5.2
3.7
59.3
57.1
%
0.48
25
190
12
79
1.52
0.62
1.8
1.2
94.7
7.3
u/ml
—
7
31
6
105
0.57
0.62
2.0
2.1
33.5
32.3
pg
—
6
105
44
362
1.22
0.61
1.5
1.6
296.6
306.7
mu/l
0.07
39
326
0
21
0.00
0.60
0.0
2.4
—
—
—
0
0
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
6
35
1.72
0.57
1.0
11.5
—
—
—
0
0
8
54
1.48
0.57
1.5
1.3
—
—
—
0
0
14
98
1.43
0.56
1.7
1.3
—
—
—
0
0
14
98
1.43
0.56
1.9
2.4
—
—
—
0
0
19
141
1.35
0.56
1.6
1.5
—
—
—
0
0
5
89
0.56
0.56
3.0
2.7
—
—
—
0
0
15
107
1.41
0.55
2.3
2.9
—
—
—
0
0
37
304
1.22
0.53
5.9
5.4
9.5
8.9
kpa
0.87
37
286
13
91
1.43
0.53
1.4
1.1
—
—
—
0
0
290
2751
1.07
0.46
3.7
3.1
6.6
7.4
mmol/l
2.27
256
2328
31
256
1.22
0.44
1.6
1.9
—
—
—
0
0
5
31
1.62
0.43
1.2
1.1
—
—
—
0
0
5
31
1.62
0.43
1.0
1.0
—
—
—
0
0
5
32
1.56
0.42
2.2
2.2
—
—
—
0
0
0
15
0.00
0.41
0.0
2.5
—
—
—
0
0
0
17
0.00
0.40
0.0
2.4
—
4385.0
—
0
17
0
17
0.00
0.40
0.0
1.0
—
—
—
0
0
0
17
0.00
0.40
0.0
3.2
—
44.0
—
0
12
34
288
1.19
0.39
1.4
1.5
7.8
9.7
u/l
0.68
27
224
14
106
1.32
0.39
1.0
1.1
—
—
—
0
0
18
143
1.26
0.37
1.1
1.2
—
—
—
0
0
48
422
1.14
0.36
12.3
10.7
—
—
—
0
0
43
375
1.15
0.36
7.3
3.5
0.6
0.7
%
0.40
43
364
259
2472
1.06
0.36
3.8
3.2
1434.4
368.1
mg/l
1.08
154
1543
6
42
1.43
0.35
1.0
1.5
—
—
—
0
0
15
118
1.27
0.33
1.2
1.5
—
—
—
0
0
10
74
1.35
0.32
1.2
1.2
—
—
—
0
0
19
157
1.21
0.29
2.2
1.4
—
—
—
0
0
182
1731
1.06
0.29
5.1
4.5
1.7
2.5
ug/l
1.90
165
1556
10
76
1.32
0.28
1.0
1.5
—
—
—
0
0
13
161
0.81
0.27
2.7
3.1
—
—
—
0
0
35
394
0.88
0.26
3.3
3.3
26.3
25.1
mmol/l
1.40
35
382
24
207
1.16
0.25
2.3
2.3
414.3
85.4
ug/min
—
10
128
35
391
0.89
0.24
1.4
1.6
—
—
—
0
0
5
38
1.32
0.23
1.0
1.0
—
—
—
0
0
33
369
0.89
0.23
1.8
2.3
3656.0
4011.3
u/l
—
9
160
12
97
1.24
0.23
7.7
4.2
—
—
—
0
0
5
39
1.28
0.23
1.4
1.2
—
—
—
0
0
5
40
1.25
0.22
1.4
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
11.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
17.1
—
0
10
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
5.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
8.6
—
—
—
0
0
0
14
0.00
0.20
0.0
2.4
—
—
—
0
0
64
597
1.08
0.20
3.0
2.9
—
—
—
0
0
92
972
0.94
0.20
1.2
1.3
—
—
—
0
0
22
193
1.14
0.19
1.8
1.4
216.9
247.1
u/ml
0.21
14
110
34
308
1.11
0.19
7.3
7.4
1.5
1.4
mg/l
0.49
34
288
36
392
0.92
0.17
1.4
1.6
—
—
—
0
0
5
66
0.76
0.17
3.0
1.3
—
67.2
—
0
5
28
309
0.90
0.17
12.0
9.6
—
—
—
0
0
36
391
0.92
0.16
1.4
1.6
—
—
—
0
0
16
139
1.15
0.16
1.4
1.5
—
—
—
0
0
29
266
1.09
0.14
1.2
1.3
—
—
—
0
0
13
113
1.15
0.13
1.3
1.1
—
—
—
0
0
36
386
0.93
0.13
1.4
1.6
—
—
—
0
0
21
190
1.11
0.12
5.3
3.7
32.0
26.3
mg/l
—
10
117
15
168
0.89
0.11
1.3
1.2
—
—
—
0
0
28
302
0.93
0.11
1.4
1.5
—
—
—
0
0
34
362
0.94
0.10
1.4
1.6
—
—
—
0
0
16
177
0.90
0.10
1.9
2.6
20.7
16.2
%
—
7
96
52
496
1.05
0.10
6.9
3.9
126.1
128.4
g/l
0.34
52
487
254
2503
1.02
0.08
3.9
3.6
—
—
—
0
0
5
62
0.81
0.08
1.2
1.1
—
—
—
0
0
5
62
0.81
0.08
1.0
1.1
—
—
—
0
0
24
256
0.94
0.08
1.5
1.4
99.4
223.3
pmol/l
0.97
24
251
264
2606
1.02
0.07
4.5
3.9
8.5
8.4
mg/mmol
0.02
159
1606
265
2618
1.02
0.07
1.5
1.5
—
—
—
0
0
11
100
1.10
0.05
1.0
1.1
—
—
—
0
0
17
180
0.94
0.04
5.0
4.0
2.3
2.6
mmol/l
—
10
125
21
200
1.05
0.03
1.5
2.1
—
—
—
0
0
12
128
0.94
0.02
1.3
1.6
—
—
—
0
0
18
184
0.98
0.00
5.2
3.5
—
—
—
0
0
22
216
1.02
0.00
5.3
3.7
7.4
7.4
ph
0.00
17
177
20
202
0.99
0.00
1.3
1.3
—
—
—
0
0
16
157
1.02
0.00
6.3
3.0
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
17
170
1.00
0.00
1.5
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
12.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.9
—
4.3
—
0
8
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
9
92
0.98
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H7_CONJUNCTIVITISCHRON and mortality.

Females

Parameter HR [95% CI] p-value
H7_CONJUNCTIVITISCHRON 1.053 [0.93, 1.19] 0.416
Birth year 0.995 [0.99, 1.0] 0.315

During the follow-up period (1.1.1998 — 31.12.2019), 451 out of 4367 females with H7_CONJUNCTIVITISCHRON died.

Males

Parameter HR [95% CI] p-value
H7_CONJUNCTIVITISCHRON 1.056 [0.9, 1.23] 0.494
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 290 out of 2698 males with H7_CONJUNCTIVITISCHRON died.

Mortality risk

Mortality risk for people of age

years, who have H7_CONJUNCTIVITISCHRON.

N-year risk Females Males
1 0.113% 0.184%
5 0.617% 1.142%
10 1.576% 2.972%
15 2.77% 5.727%
20 5.35% 9.739%

Relationships between endpoints

Index endpoint: H7_CONJUNCTIVITISCHRON – Chronic conjunctivitis

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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