Other infections specific to the perinatal period

P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 P39
  • Cause of death: ICD-10 P39

2 out of 7 registries used, show all original rules.

209

4. Check minimum number of events

None

209

5. Include endpoints

None

209

6. Filter based on genotype QC (FinnGen only)

201

Control definitions (FinnGen only)

Control exclude
P16_INFECTIONS_SPECIFIC_PERINA_PERIOD

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
P3
Name in latin
Alii infectiones temporis perinatalis specificae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15148 6214 8934
Only index persons 9358 3723 5635
Unadjusted period prevalence (%)
Whole population 0.22 0.18 0.25
Only index persons 0.18 0.14 0.22
Median age at first event (years)
Whole population - 0.00 0.00
Only index persons 0.00 0.00 0.00

-FinnGen-

Key figures

All Female Male
Number of individuals 201 107 94
Unadjusted period prevalence (%) 0.04 0.04 0.04
Median age at first event (years) 0.00 0.00 0.00

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
209
Matched controls
2088
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
P39.9
ICD-10 Finland
Infection specific to the perinatal period, unspecified
+∞
199.2
158
*
P39.1
ICD-10 Finland
Neonatal conjunctivitis and dacryocystitis
+∞
26.6
25
*
P01.10
ICD-10 Finland
Fetus and newborn affected by premature rupture of membranes 1-7 days before delivery
31.3
15.5
20
7
P22.1
ICD-10 Finland
Transient tachypnoea of newborn
11.6
12.6
23
22
P36.90
ICD-10 Finland
Suspected bacterial sepsis of newborn
+∞
11.6
11
*
P39.4
ICD-10 Finland
Neonatal skin infection
+∞
11.6
11
*
P39.0
ICD-10 Finland
Neonatal infective mastitis
+∞
10.5
10
*
P07.3
ICD-10 Finland
Other preterm infants
3.4
6.1
22
69

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
24
105
2.45
3.68
3.1
3.0
—
—
—
0
0
6
7
8.77
3.28
2.2
1.6
32.33
32.86
pg
—
6
7
20
89
2.38
2.97
6.4
4.7
0.40
0.49
%
—
5
35
20
89
2.38
2.97
6.5
6.2
0.00
0.00
%
—
5
27
20
92
2.30
2.77
6.4
6.1
0.00
0.03
%
—
5
33
0
69
0.00
2.65
0.0
5.1
—
—
—
0
0
20
96
2.20
2.52
6.4
6.0
0.20
0.57
%
—
5
37
45
299
1.64
2.14
3.5
3.5
0.00
0.00
estimate
-0.00
22
108
36
226
1.71
2.11
3.6
4.6
—
—
—
0
0
22
118
1.96
2.10
1.4
1.4
—
—
—
0
0
0
55
0.00
2.10
0.0
1.1
—
—
—
0
0
43
293
1.59
1.84
3.5
3.4
7.39
7.39
ph
—
8
55
5
12
4.24
1.83
1.0
1.1
—
—
—
0
0
17
90
1.97
1.70
2.5
2.7
4.86
5.13
pmol/l
0.71
17
81
6
20
3.05
1.59
6.2
6.8
—
—
—
0
0
8
33
2.48
1.55
18.8
14.8
71.13
71.92
%
—
8
33
0
45
0.00
1.51
0.0
1.4
—
—
—
0
0
106
894
1.37
1.47
9.5
11.4
0.00
0.00
e9/l
-0.00
82
677
24
364
0.61
1.44
2.3
3.7
—
—
—
0
0
155
1395
1.43
1.43
10.1
11.7
3.88
3.89
mmol/l
0.15
150
1340
174
1609
1.48
1.30
9.6
10.4
21.27
22.44
mg/l
0.16
116
1046
62
767
0.73
1.29
1.6
1.8
0.31
2.34
u/ml
3.70
11
142
43
318
1.44
1.27
3.5
2.8
—
—
—
0
0
6
25
2.44
1.25
1.7
4.8
8.55
9.15
kpa
—
6
25
6
25
2.44
1.25
1.7
4.8
5.63
4.85
kpa
—
6
25
154
1399
1.38
1.23
10.1
11.7
139.50
139.51
mmol/l
0.02
149
1353
13
222
0.56
1.23
1.6
1.7
—
—
—
0
0
13
71
1.88
1.22
1.5
1.3
—
—
—
0
0
22
143
1.60
1.17
2.2
2.3
6.99
5.67
u/l
0.45
16
100
5
20
2.53
1.15
1.2
1.1
—
—
—
0
0
8
40
2.04
1.13
18.6
13.1
—
—
—
0
0
8
41
1.99
1.10
4.1
3.9
2.61
3.11
e9/l
—
8
41
8
41
1.99
1.10
4.4
4.4
43.00
50.32
%
—
8
41
39
294
1.40
1.04
3.1
3.5
468.13
629.97
mosm/kgh2o
3.48
32
264
124
1366
0.77
1.03
4.5
3.7
2.10
1.96
mu/l
0.41
111
1283
9
47
1.95
1.03
2.7
6.5
202.78
454.32
mg/l
—
9
47
13
78
1.71
0.93
1.5
1.5
—
—
—
0
0
165
1540
1.33
0.92
13.1
14.7
13.36
13.04
%
1.01
158
1507
39
494
0.74
0.91
1.8
1.5
—
—
—
0
0
22
305
0.69
0.88
1.3
1.2
—
—
—
0
0
18
121
1.53
0.85
1.8
1.4
508.55
63207967.16
pmol/l
0.50
11
106
0
27
0.00
0.78
0.0
1.9
—
39.96
—
0
27
0
28
0.00
0.76
0.0
1.1
—
—
—
0
0
51
422
1.27
0.74
4.2
4.5
0.08
0.17
e6/l
1.07
34
325
9
55
1.66
0.74
17.0
12.0
0.72
0.57
%
—
9
55
13
85
1.56
0.70
1.5
1.5
—
—
—
0
0
51
426
1.26
0.69
4.4
4.4
—
—
—
0
0
7
43
1.65
0.67
3.1
6.8
—
—
—
0
0
5
28
1.80
0.66
1.0
1.3
0.88
4.29
u/ml
—
5
28
54
458
1.24
0.64
4.9
4.6
17.49
27.39
e6/l
0.45
38
361
25
193
1.33
0.61
2.2
2.4
—
—
—
0
0
0
20
0.00
0.60
0.0
1.3
—
21.40
—
0
5
0
20
0.00
0.60
0.0
1.3
—
29.50
—
0
6
0
20
0.00
0.60
0.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
3.3
—
6.09
—
0
14
23
177
1.34
0.57
1.2
1.2
8.80
14.04
iu/ml
—
5
37
70
620
1.19
0.54
3.6
3.3
0.00
0.00
estimate
-0.00
22
107
70
620
1.19
0.54
5.1
4.7
0.00
0.00
estimate
-0.00
22
114
18
135
1.36
0.53
16.1
12.2
1.24
1.32
mmol/l
0.16
18
128
37
308
1.24
0.52
4.5
3.4
7.97
8.51
e6/l
0.08
31
278
11
75
1.49
0.51
1.0
1.0
—
—
—
0
0
81
891
0.85
0.51
2.7
2.7
1.36
1.40
mmol/l
0.36
76
841
190
1845
1.32
0.49
13.5
15.0
4.65
4.66
e12/l
0.11
174
1755
70
625
1.18
0.49
3.7
3.3
0.00
0.00
estimate
-0.00
22
109
11
153
0.70
0.48
2.1
1.8
—
—
—
0
0
8
117
0.67
0.47
1.3
1.4
—
—
—
0
0
8
116
0.68
0.47
1.1
1.4
—
—
—
0
0
190
1847
1.30
0.47
13.5
15.0
6.85
6.61
e9/l
0.75
175
1756
22
273
0.78
0.46
1.3
1.9
—
—
—
0
0
156
1489
1.18
0.46
7.4
8.6
23.37
24.76
u/l
0.48
146
1424
22
272
0.79
0.45
1.3
1.9
—
—
—
0
0
22
272
0.79
0.45
1.3
1.9
—
—
—
0
0
22
272
0.79
0.45
1.3
1.8
—
—
—
0
0
189
1839
1.28
0.43
13.6
15.1
269.20
268.14
e9/l
0.08
173
1754
5
31
1.63
0.43
2.8
5.5
—
—
—
0
0
6
94
0.63
0.43
2.3
2.1
—
—
—
0
0
8
57
1.42
0.42
3.0
1.6
—
—
—
0
0
5
33
1.53
0.41
1.2
1.4
—
—
—
0
0
78
849
0.87
0.41
2.7
2.6
1.26
1.07
mmol/l
1.09
73
809
115
1219
0.87
0.41
4.3
3.3
14.39
14.33
pmol/l
0.10
102
1088
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
37562.50
—
0
16
0
16
0.00
0.41
0.0
1.9
—
—
—
0
0
62
686
0.86
0.41
1.5
1.7
1.68
1.63
g/l
0.13
33
360
36
308
1.20
0.41
1.6
1.4
101.59
100.00
pmol/l
0.07
19
161
17
213
0.78
0.39
1.3
1.9
—
—
—
0
0
0
19
0.00
0.39
0.0
2.6
—
—
—
0
0
27
320
0.82
0.39
1.4
1.6
—
—
—
0
0
189
1843
1.26
0.39
14.2
15.5
39.92
40.10
%
0.19
181
1763
21
253
0.81
0.35
1.3
1.9
—
—
—
0
0
61
554
1.14
0.34
5.7
5.2
67.68
62.38
e6/l
0.04
39
372
6
89
0.66
0.33
3.8
1.3
3.15
3.93
e9/l
—
6
83
30
258
1.19
0.33
4.9
8.1
—
—
—
0
0
74
797
0.89
0.32
4.5
3.5
75.57
51.37
ug/l
0.36
69
748
69
637
1.12
0.30
2.2
2.1
—
—
—
0
0
34
299
1.16
0.29
9.6
10.9
22.82
23.77
mmol/l
1.09
34
299
89
944
0.90
0.29
2.1
2.2
5.62
5.32
mmol/l
0.43
75
848
108
1024
1.11
0.29
4.7
4.6
8.73
6.72
mm/h
0.68
102
949
30
262
1.17
0.28
3.6
4.3
3.60
3.24
e6/l
0.07
15
156
74
791
0.90
0.28
3.5
2.9
36.80
36.59
mmol/mol
0.05
69
744
30
265
1.15
0.25
1.4
1.7
—
—
—
0
0
33
295
1.14
0.24
7.5
12.8
—
—
—
0
0
5
38
1.32
0.23
1.4
1.4
—
—
—
0
0
32
286
1.14
0.23
2.7
1.7
—
—
—
0
0
71
667
1.10
0.22
9.6
11.3
1.22
1.22
mmol/l
0.04
62
607
8
104
0.76
0.21
1.1
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
5.5
—
0.57
—
0
10
0
10
0.00
0.21
0.0
2.4
—
34.70
—
0
10
0
10
0.00
0.21
0.0
1.2
—
28.91
—
0
10
0
10
0.00
0.21
0.0
2.1
—
—
—
0
0
0
10
0.00
0.21
0.0
2.4
—
27.00
—
0
10
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
2.0
—
49.64
—
0
11
0
12
0.00
0.21
0.0
2.5
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
285.69
—
0
13
0
13
0.00
0.21
0.0
2.6
—
18.70
—
0
13
156
1595
0.91
0.20
11.6
13.9
335.33
335.31
g/l
0.01
156
1572
57
534
1.09
0.19
3.4
3.1
6.29
6.11
ph
—
7
49
93
891
1.08
0.18
4.5
4.2
—
—
—
0
0
86
895
0.93
0.16
2.7
2.7
2.58
2.63
mmol/l
0.26
81
840
34
368
0.91
0.16
2.9
3.7
128.73
91.46
ug/g
0.42
26
284
163
1598
1.09
0.16
7.3
7.4
—
—
—
0
0
38
352
1.10
0.16
2.8
2.3
—
—
—
0
0
6
77
0.77
0.16
1.0
1.9
—
—
—
0
0
35
323
1.10
0.15
12.4
13.0
25.03
25.08
mmol/l
0.04
35
323
9
82
1.10
0.15
1.2
1.1
—
—
—
0
0
19
169
1.14
0.15
1.2
1.1
1.02
9.58
u/ml
—
5
56
51
481
1.08
0.14
4.8
8.0
12.52
12.63
umol/l
0.01
45
444
11
128
0.85
0.14
1.2
2.3
—
—
—
0
0
25
228
1.11
0.14
1.3
1.4
—
13.13
—
0
8
94
970
0.94
0.13
8.2
9.7
0.58
0.54
e9/l
0.54
79
819
96
990
0.94
0.13
8.5
10.4
0.19
0.20
e9/l
0.16
82
852
34
364
0.92
0.13
2.0
1.7
—
—
—
0
0
17
152
1.13
0.12
1.4
1.5
—
—
—
0
0
94
968
0.95
0.12
8.2
9.7
0.04
0.03
e9/l
2.05
79
817
48
505
0.93
0.12
1.6
1.8
—
—
—
0
0
5
47
1.06
0.09
1.4
4.6
28.20
28.23
%
—
5
47
34
321
1.07
0.09
9.9
11.3
0.66
1.42
mmol/l
0.55
28
260
6
53
1.13
0.09
1.3
1.2
—
—
—
0
0
6
58
1.03
0.08
11.7
14.5
97.40
95.14
%
—
6
58
10
88
1.14
0.08
1.2
1.1
—
—
—
0
0
8
75
1.07
0.07
1.3
1.6
—
—
—
0
0
7
82
0.85
0.07
1.1
1.3
—
—
—
0
0
34
324
1.06
0.07
10.0
11.2
5.96
5.93
kpa
0.07
34
310
8
92
0.86
0.07
3.1
10.7
0.13
0.34
g/l
—
8
77
52
536
0.96
0.06
6.0
10.7
—
—
—
0
0
98
997
0.97
0.06
7.9
9.6
2.20
2.14
e9/l
0.27
84
865
33
316
1.05
0.06
2.4
1.8
—
—
—
0
0
88
863
1.03
0.05
6.2
5.4
116.27
117.42
u/l
0.05
82
808
35
337
1.05
0.05
2.9
3.2
—
—
—
0
0
32
330
0.96
0.03
3.2
2.9
1.02
1.02
kg/l
—
6
37
104
1027
1.02
0.03
9.1
11.3
3.54
3.43
e9/l
0.20
87
868
32
329
0.97
0.02
2.7
5.1
1.16
1.12
inr
0.13
20
104
18
188
0.95
0.02
1.2
2.4
—
—
—
0
0
32
312
1.03
0.01
10.1
10.9
5.27
4.97
kpa
0.40
32
299
42
412
1.02
0.01
2.7
3.8
2.62
2.70
mg/l
0.10
37
362
51
517
0.98
0.01
2.7
2.1
—
—
—
0
0
27
263
1.03
0.01
1.9
1.6
—
—
—
0
0
91
902
1.01
0.01
9.2
9.9
—
—
—
0
0
24
234
1.03
0.00
2.9
5.4
0.51
1.44
mg/l
1.33
14
161
13
131
0.99
0.00
14.7
9.9
105.54
105.11
mmol/l
0.12
13
131
22
215
1.02
0.00
10.4
14.3
6.12
5.10
mmol/l
0.56
22
210
16
159
1.01
0.00
1.3
1.3
3.89
4.06
u/ml
0.01
11
113
17
168
1.01
0.00
2.8
3.2
2143.71
1350.32
ng/l
—
7
85
21
213
0.98
0.00
2.3
2.3
13.57
15.70
ng/l
—
7
70
12
123
0.97
0.00
1.4
2.4
—
—
—
0
0
14
135
1.04
0.00
1.6
1.9
239.13
174.05
u/ml
—
8
59
6
60
1.00
0.00
11.7
14.1
0.57
0.70
%
—
6
60
6
60
1.00
0.00
11.7
14.1
0.88
1.18
%
—
6
60
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
4.4
—
4.26
—
0
7
5
57
0.87
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
8.1
—
647.43
—
0
7
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
255.47
—
0
9
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
5
49
1.02
-0.00
11.4
13.7
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.8
—
3.74
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
20.62
—
0
5
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
5
56
0.89
-0.00
1.4
4.9
22.60
16.52
%
—
5
56
0
5
0.00
-0.00
0.0
2.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.0
—
—
—
0
0
5
49
1.02
-0.00
1.4
4.4
9.60
8.12
%
—
5
49
5
49
1.02
-0.00
1.4
4.4
67.40
68.80
%
—
5
49
0
5
0.00
-0.00
0.0
1.2
—
107.60
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
2000.00
—
0
5
0
6
0.00
-0.00
0.0
2.5
—
3.52
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
107.33
—
0
6
0
7
0.00
-0.00
0.0
1.0
—
803.71
—
0
7
0
7
0.00
-0.00
0.0
12.4
—
46.36
—
0
7
5
58
0.86
-0.00
13.6
14.5
24.00
24.05
mmol/l
—
5
58
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
69
1.01
-0.00
2.0
4.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: P16_OTH_INFECTIONS_SPECIFIC_PERINA_PERIOD – Other infections specific to the perinatal period

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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