Other/unspecified soft tissue disorders related to use, overuse and pressure

M13_OVERUSENAS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M70.8, M70.9
  • Hospital discharge: ICD-9 7266A
  • Cause of death: ICD-10 M70.8, M70.9
  • Cause of death: ICD-9 7266A

2 out of 7 registries used, show all original rules.

1143

4. Check minimum number of events

None

1143

5. Include endpoints

None

1143

6. Filter based on genotype QC (FinnGen only)

1143

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 7457 4293 3132
Only index persons 7151 4134 3017
Unadjusted period prevalence (%)
Whole population 0.11 0.12 0.09
Only index persons 0.14 0.15 0.12
Median age at first event (years)
Whole population 44.30 46.78 40.94
Only index persons 43.99 46.43 40.63

-FinnGen-

Key figures

All Female Male
Number of individuals 1143 766 377
Unadjusted period prevalence (%) 0.23 0.26 0.17
Median age at first event (years) 51.04 49.82 53.52

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1019
Matched controls
10188
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M70.8
ICD-10 Finland
Other soft tissue disorders related to use, overuse and pressure
2277.0
323.0
660
8
M70.9
ICD-10 Finland
Unspecified soft tissue disorder related to use, overuse and pressure
470.8
323.0
344
11
M79.6
ICD-10 Finland
Pain in limb
4.3
91.1
447
1564
M01AH05
ATC
etoricoxib; oral
3.4
71.4
717
4191
M70.6
ICD-10 Finland
Trochanteric bursitis
6.3
70.9
208
400
N03AX16
ATC
pregabalin; oral
4.1
69.3
325
1038
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.7
69.0
272
734
M25.5
ICD-10 Finland
Pain in joint
3.4
60.9
381
1517
N02AX02
ATC
tramadol; systemic, rectal
3.1
60.5
487
2322
N03AX12
ATC
gabapentin; oral
4.5
56.1
224
599
M54.5
ICD-10 Finland
Low back pain
3.0
54.0
413
1863
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
5.9
53.2
160
311
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
17.0
49.1
79
50
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
12.8
47.8
87
74
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.7
47.2
525
2914
M54.4
ICD-10 Finland
Lumbago with sciatica
3.8
47.0
232
741
M01AB05
ATC
diclofenac; systemic, rectal
2.6
42.7
733
5052
Z50.1
ICD-10 Finland
Other physical therapy
6.7
41.4
110
180
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
5.1
41.0
139
307
M03BX02
ATC
tizanidine; oral
2.5
40.7
693
4685
M01AE02
ATC
naproxen; oral, rectal
2.4
39.9
630
4076
M79.0
ICD-10 Finland
Rheumatism, unspecified
34.2
37.9
49
15
M79.1
ICD-10 Finland
Myalgia
4.0
37.1
161
453
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
3.6
36.6
185
592
M02AA07
ATC
piroxicam; topical
2.5
36.2
395
2077
M03BC01
ATC
orphenadrine (citrate); systemic
2.7
36.1
307
1401
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
101.3
36.0
39
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
12.5
35.8
65
55
NBG10
NOMESCO Finland
Acromioplastia
98.6
35.0
38
*
N06AX21
ATC
duloxetine; oral
3.9
33.7
152
441
R4110
NOMESCO Finland
Physiotherapy
2.6
33.2
311
1490
M01AE03
ATC
ketoprofen; systemic, rectal
2.3
32.8
409
2273
N02AJ06
ATC
codeine and paracetamol; systemic
2.3
32.3
403
2235
N06AA09
ATC
amitriptyline; systemic
4.1
31.4
130
348
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.3
31.2
383
2097
A02BC02
ATC
pantoprazole; systemic
2.2
31.0
665
4697
M01AH02
ATC
rofecoxib; oral
3.4
30.9
164
542
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.6
30.4
112
268
M67.4
ICD-10 Finland
Ganglion
7.4
30.0
73
105
ZXA00
NOMESCO Finland
Right side
2.5
29.9
286
1373
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
19.6
29.8
45
24
A02BC05
ATC
esomeprazole; systemic
2.2
28.9
428
2536
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.3
28.0
155
526
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
15.0
27.7
46
32
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.5
27.5
103
250
L13
ICPC
Hip symptom/complaint
2.9
27.4
186
726
7266A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[BURSITIS PEDIS ANSERINI]
+∞
27.2
26
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
3.6
27.2
134
416
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
7.0
27.0
68
103
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
5.2
26.9
86
176
M01AC06
ATC
meloxicam; systemic, rectal
2.2
26.7
386
2242
J01AA02
ATC
doxycycline; systemic
2.2
26.7
797
6272
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
10.9
26.5
51
49
M01AH01
ATC
celecoxib; oral (coxibs)
2.7
26.0
206
880
J01DB01
ATC
cefalexin; oral
2.3
26.0
842
6829
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.1
25.7
466
2966
A02BC01
ATC
omeprazole; systemic
2.3
25.1
287
1487
M48.0
ICD-10 Finland
Spinal stenosis
3.5
25.1
126
396
M79.7
ICD-10 Finland
Fibromyalgia
10.9
25.0
48
46
X59
ICD-10 Finland
Exposure to unspecified factor
2.6
24.5
210
936
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.6
24.2
193
826
N02BE01
ATC
paracetamol; systemic, rectal
2.3
23.9
862
7146
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
245.5
23.7
24
*
M77.1
ICD-10 Finland
Lateral epicondylitis
4.3
23.7
91
226
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
23.4
259
1317
M01AX17
ATC
nimesulide; oral
2.3
23.1
255
1292
M01AE01
ATC
ibuprofen; systemic, rectal
2.8
23.0
936
8146
G54.0
ICD-10 Finland
Brachial plexus disorders
9.6
23.0
47
51
R51.80
ICD-10 Finland
Headache
2.8
22.6
164
662
L08
ICPC
Shoulder symptom/complaint
2.6
22.6
186
807
R5599
NOMESCO Finland
Other rehabilitation service
7.9
22.6
52
69
H02AB06
ATC
prednisolone; systemic
2.0
22.5
454
2963
M65.3
ICD-10 Finland
Trigger finger
9.1
22.3
47
54
R52.2
ICD-10 Finland
Other chronic pain
7.6
22.0
52
72
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.2
21.7
278
1500
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
21.3
242
1239
M01AB55
ATC
diclofenac, combinations; oral
4.1
20.9
84
218
NCM10
NOMESCO Finland
Fasciotomy of forearm
112.3
20.6
22
*
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
42.6
20.5
25
6
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
13.4
20.3
35
27
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
33.3
20.3
26
8
A06AC01
ATC
ispaghula (psylla seeds); oral
2.2
20.1
247
1305
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
19.3
20.0
30
16
L03
ICPC
Low back symptom/complaint
2.2
19.9
248
1320
SPAT1236
SPAT
Informing family of child’s disability
7.2
19.8
48
69
M76.6
ICD-10 Finland
Achilles tendinitis
5.6
19.8
58
108
ZXA05
NOMESCO Finland
Left side
2.2
19.7
243
1282
R01AD09
ATC
mometasone; nasal
1.9
19.5
469
3205
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.2
19.1
235
1236
Z71.9
ICD-10 Finland
Counselling, unspecified
3.6
18.9
89
265
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
7.3
18.8
45
64
J01FA10
ATC
azithromycin; systemic
1.8
18.7
600
4488
L17
ICPC
Foot/toe symptom/complaint
2.1
18.6
243
1315
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.9
18.5
78
212
NGM10
NOMESCO Finland
Fasciotomy of of knee or lower leg
25.6
18.3
25
10
Z01.8
ICD-10 Finland
Other specified special examinations
2.2
18.3
218
1131
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.9
18.2
121
459
M02AA10
ATC
ketoprofen; topical
2.4
18.1
168
773
Z01.7
ICD-10 Finland
Laboratory examination
2.7
17.9
131
529
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.2
17.8
99
332
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.8
17.7
119
456
M77.4
ICD-10 Finland
Metatarsalgia
4.3
17.7
66
160
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
5.9
17.6
49
86
R03AC02
ATC
salbutamol; inhalant
1.8
17.5
508
3648
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
10.3
17.5
34
34
A02BC03
ATC
lansoprazole; oral
2.0
17.3
271
1570
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.3
17.2
184
904
J01MA02
ATC
ciprofloxacin; systemic
1.8
17.2
370
2407
J01FF01
ATC
clindamycin; systemic
2.0
17.1
272
1585
J01FA09
ATC
clarithromycin; systemic
1.9
17.0
326
2034
A02BA02
ATC
ranitidine; systemic
2.2
16.8
188
941
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
+∞
16.7
16
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
5.5
16.7
49
92
Z12.3
ICD-10 Finland
Special screening examination for neoplasm of breast
11.9
16.6
30
26
X58
ICD-10 Finland
Exposure to other specified factors
2.5
16.6
145
644
Z13.5
ICD-10 Finland
Special screening examination for eye and ear disorders
13.7
16.5
28
21
M47.9
ICD-10 Finland
Spondylosis, unspecified
6.6
16.4
42
66
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.6
16.3
122
498
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.7
16.3
47
86
R05FB02
ATC
cough suppressants and expectorants
1.8
16.2
369
2430
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.2
15.9
61
152
J01DA01
ATC
[U] cefalexin; systemic
1.7
15.8
621
4830
J45.9
ICD-10 Finland
Asthma, unspecified
2.2
15.7
168
825
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.2
15.7
168
826
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
26.7
15.6
21
8
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
26.7
15.6
21
8
A01
ICPC
Pain general/multiple sites
3.2
15.6
83
272
R42
ICD-10 Finland
Dizziness and giddiness
2.1
15.6
194
1019
G44.2
ICD-10 Finland
Tension-type headache
2.4
15.6
144
658
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
9.1
15.5
32
36
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
6.0
15.2
42
73
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
4.2
15.2
58
144
N06AX16
ATC
venlafaxine; oral
2.3
15.2
149
702
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
15.1
289
1785
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
4.5
15.0
53
122
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.7
15.0
109
435
M72.2
ICD-10 Finland
Plantar fascial fibromatosis
3.2
14.9
80
264
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
14.9
173
881
WX002
NOMESCO Finland
Sedation and analgesia
2.1
14.7
188
996
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
14.6
96
360
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
14.6
259
1556
M54.6
ICD-10 Finland
Pain in thoracic spine
3.2
14.6
78
257
N03AE01
ATC
clonazepam; systemic
3.5
14.5
69
208
Z71.8
ICD-10 Finland
Other specified counselling
1.9
14.3
244
1443
M54.3
ICD-10 Finland
Sciatica
3.5
14.0
65
192
L28
ICPC
Limited function/disability (L)
2.3
13.9
131
602
S83.2
ICD-10 Finland
Tear of meniscus, current
3.0
13.9
81
283
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
11.6
13.8
25
22
M75.8
ICD-10 Finland
Other shoulder lesions
5.5
13.7
40
75
WX320
NOMESCO Finland
Spinalanesthesy
2.0
13.7
211
1201
M70.7
ICD-10 Finland
Other bursitis of hip
7.1
13.4
32
46
R06.0
ICD-10 Finland
Dyspnoea
1.9
13.4
207
1178
M79.9
ICD-10 Finland
Soft tissue disorder, unspecified
26.1
13.4
18
7
R52.9
ICD-10 Finland
Pain, unspecified
2.7
13.4
91
352
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.7
13.3
59
168
XF402
NOMESCO Finland
ECG with work load test
2.5
13.3
107
455
M76.0
ICD-10 Finland
Gluteal tendinitis
8.7
13.3
28
33
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.8
13.3
250
1525
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
10.6
13.3
25
24
ZXA10
NOMESCO Finland
Bilateral
2.0
13.2
173
925
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
13.1
217
1266
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.3
13.1
124
573
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.5
13.1
102
426
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
4.2
13.0
49
121
M77.0
ICD-10 Finland
Medial epicondylitis
6.5
13.0
33
52
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.3
12.9
48
117
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.1
12.8
70
235
R03AC03
ATC
terbutaline; inhalant
2.2
12.8
146
734
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.3
12.6
65
209
UJF32
NOMESCO Finland
Coloscopy
1.8
12.5
227
1367
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.5
12.5
59
178
G57.1
ICD-10 Finland
Meralgia paraesthetica
8.1
12.4
27
34
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.7
12.2
84
328
J31.0
ICD-10 Finland
Chronic rhinitis
2.6
12.1
90
367
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
11.2
12.1
22
20
S18
ICPC
Laceration/cut
1.7
12.0
359
2511
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
21.6
12.0
17
8
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
9.4
12.0
24
26
N06AX11
ATC
mirtazapine; oral
1.7
11.9
294
1947
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
11.9
494
3772
K07.60
ICD-10 Finland
Snapping jaw
3.6
11.8
52
148
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
3.8
11.8
49
133
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
5.9
11.7
32
56
R01AD08
ATC
fluticasone; nasal
1.7
11.7
285
1880
J01FA06
ATC
roxithromycin; oral
1.6
11.7
377
2691
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
11.7
123
595
R52.1
ICD-10 Finland
Chronic intractable pain
23.2
11.6
16
7
J02AC01
ATC
fluconazole; systemic
1.6
11.6
410
2994
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
11.3
11.6
21
19
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.3
11.5
57
178
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
11.5
96
416
R03DC03
ATC
montelukast; oral
2.0
11.5
159
865
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.1
11.5
65
222
L29
ICPC
Musculoskeletal sympt/complt other
2.8
11.5
75
283
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
5.3
11.4
34
66
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
11.4
86
353
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.4
11.4
97
425
D06
ICPC
Abdominal pain localized other
2.6
11.3
84
340
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
6.3
11.3
29
47
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
11.3
364
2590
M54
ICD-10 Finland
Dorsalgia
2.3
11.2
109
510
J01CA04
ATC
amoxicillin; systemic
1.7
11.1
797
6933
M01AX05
ATC
glucosamine; oral
2.0
11.1
156
855
R07.3
ICD-10 Finland
Other chest pain
2.5
11.1
86
358
XA402
NOMESCO Finland
ENMG
5.2
11.0
33
65
M54.2
ICD-10 Finland
Cervicalgia
2.7
10.9
75
289
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
6.1
10.9
29
49
B01AB05
ATC
enoxaparin; parenteral
1.7
10.9
254
1644
M13.9
ICD-10 Finland
Arthritis, unspecified
2.9
10.9
68
249
Z00.8
ICD-10 Finland
Other general examinations
2.7
10.9
76
298
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
10.9
216
1332
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.5
10.9
49
143
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.4
10.8
94
416
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.5
10.8
88
376
R06AX27
ATC
desloratadine; oral
1.7
10.8
270
1787
R4120
NOMESCO Finland
Occupational therapy
2.9
10.8
67
245
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
9.7
10.8
21
22
N02AA05
ATC
oxycodone; systemic
2.2
10.8
108
511
M01AB08
ATC
etodolac; oral
2.6
10.7
79
321
ACC51
NOMESCO Finland
Release of median nerve
2.8
10.6
70
265
1220
FHL
Arthroscopy
3.8
10.6
44
120
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
11.4
10.6
19
17
WX110
NOMESCO Finland
Local anesthesy
1.6
10.5
659
5485
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.5
10.5
83
349
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.3
10.4
101
473
NBE45
NOMESCO Finland
Plastic repair of ligament of shoulder not using prosthetic material, arthroscopic
8.9
10.3
21
24
A03FA02
ATC
cisapride; oral, rectal
2.8
10.3
68
258
XX9CW
NOMESCO Finland
Submitting image material and/or investigation material to patient
9.7
10.3
20
21
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.4
10.3
36
84
M77.9
ICD-10 Finland
Enthesopathy, unspecified
4.4
10.3
36
84
R05
ICD-10 Finland
Cough
1.9
10.2
174
1019
XF400
NOMESCO Finland
ECG with 12 standard connections
2.0
10.2
136
726
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
3.4
10.1
48
147
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
14.7
10.0
16
11
R06AE07
ATC
cetirizine; oral
1.6
10.0
413
3102
M70.0
ICD-10 Finland
Chronic crepitant synovitis of hand and wrist
40.5
10.0
12
*
R10.2
ICD-10 Finland
Pelvic and perineal pain
5.0
10.0
31
64
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
5.7
9.9
27
48
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
26.3
9.8
13
5
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
26.3
9.8
13
5
L11
ICPC
Wrist symptom/complaint
2.5
9.7
75
311
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
5.2
9.7
29
57
L12
ICPC
Hand/finger symptom/complaint
2.0
9.7
127
675
M54.1
ICD-10 Finland
Radiculopathy
3.7
9.7
41
114
A04
ICPC
Weakness/tiredness general
2.1
9.7
106
524
L01
ICPC
Neck symptom/complaint
2.0
9.6
126
669
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
9.6
143
799
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.4
9.6
78
335
M75.2
ICD-10 Finland
Bicipital tendinitis
5.5
9.6
27
50
N06AA10
ATC
nortriptyline; systemic
5.5
9.6
27
50
P01AB01
ATC
metronidazole; oral, rectal
1.6
9.5
375
2775
M75.3
ICD-10 Finland
Calcific tendinitis of shoulder
9.2
9.5
19
21
R01AD12
ATC
fluticasone furoate; nasal
1.6
9.5
289
2007
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.8
9.5
60
223
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.7
9.5
241
1597
Z51.88
ICD-10 Finland
Other specified medical care
5.0
9.5
29
59
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.6
9.5
70
284
M66.4
ICD-10 Finland
Spontaneous rupture of other tendons
+∞
9.4
9
*
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
+∞
9.4
9
*
NHM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of ankle or foot
12.5
9.4
16
13
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.5
9.4
42
123
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
9.3
451
3498
L14
ICPC
Leg/thigh symptom/complaint
2.6
9.2
67
271
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
9.2
164
974
R03AK07
ATC
formoterol and budesonide; inhalant
1.8
9.2
175
1062
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.4
9.2
77
334
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.6
9.1
66
266
M50.3
ICD-10 Finland
Other cervical disc degeneration
4.9
9.0
28
58
NB1AT
NOMESCO Finland
Puncture of shoulder with ultrasound guidance
37.0
9.0
11
*
G56.4
ICD-10 Finland
Causalgia
37.0
9.0
11
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
9.0
79
352
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.4
9.0
77
340
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.0
8.9
115
607
R60.0
ICD-10 Finland
Localized oedema
2.2
8.9
89
422
C07AB07
ATC
bisoprolol; oral
1.5
8.9
361
2680
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.8
8.9
57
214
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
4.0
8.9
34
87
R74
ICPC
Upper respiratory infection acute
1.6
8.9
264
1820
R02
ICPC
Shortness of breath/dyspnoea
2.1
8.8
98
488
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.3
8.8
83
382
F01
ICPC
Eye pain
4.0
8.8
34
88
Z26.9
ICD-10 Finland
Need for immunization against unspecified infectious disease
4.8
8.8
28
60
M02AA15
ATC
diclofenac; topical (antiinflammatory prep., non-steroids for topical use)
2.4
8.8
73
318
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.2
8.8
90
432
L15
ICPC
Knee symptom/complaint
1.8
8.7
171
1046
WX308
NOMESCO Finland
Sacral anesthesy
50.4
8.7
10
*
R20.2
ICD-10 Finland
Paraesthesia of skin
2.6
8.7
63
255
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.0
8.7
49
168
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
8.7
94
463
R13
ICD-10 Finland
Dysphagia
2.7
8.7
59
230
R03AC12
ATC
salmeterol; inhalant
3.3
8.6
41
126
M01AX01
ATC
nabumetone; oral
3.3
8.6
41
126
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
8.6
96
478
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.6
8.6
62
249
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
4.8
8.6
27
57
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
8.4
659
5619
73398
ICD-8 Finland
Other diseases of muscle, tendon and fascia, Alii definiti
+∞
8.3
8
*
R06.4
ICD-10 Finland
Hyperventilation
5.3
8.3
24
46
E0000UV
ATC
NA
1.5
8.3
357
2677
XF404
NOMESCO Finland
Ambulatory ECG
2.2
8.3
83
395
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.4
8.2
67
289
M01AG02
ATC
tolfenamic acid; oral, rectal
1.8
8.2
155
934
D01
ICPC
Abdominal pain/cramps general
2.0
8.2
105
552
J01MA12
ATC
levofloxacin; systemic
1.8
8.2
147
875
Z01.3
ICD-10 Finland
Examination of blood pressure
7.6
8.2
18
24
N01
ICPC
Headache
2.1
8.1
95
483
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.7
8.1
53
202
N41.1
ICD-10 Finland
Chronic prostatitis
4.5
8.1
27
61
K30
ICD-10 Finland
Functional dyspepsia
2.1
8.1
94
476
D02
ICPC
Abdominal pain epigastric
2.5
8.1
59
240
D07AD01
ATC
clobetasol; topical
1.8
8.1
144
854
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.0
8.0
102
536
N05CF01
ATC
zopiclone; oral
1.6
8.0
262
1843
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
5.9
8.0
21
36
L05
ICPC
Flank/axilla symptom/complaint
2.8
8.0
51
191
L86
ICPC
Back syndrome with radiating pain
2.8
8.0
51
191
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
3.8
8.0
32
86
M35.7
ICD-10 Finland
Hypermobility syndrome
7.3
8.0
18
25
N81.6
ICD-10 Finland
Rectocele
2.5
8.0
62
261
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.1
8.0
91
456
L16
ICPC
Ankle symptom/complaint
2.1
8.0
89
443
UKC02
NOMESCO Finland
Cystoscopy
1.9
8.0
115
633
K02.1
ICD-10 Finland
Caries of dentine
1.5
8.0
527
4312
N03AF01
ATC
carbamazepine; oral, rectal
2.8
8.0
50
184
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
8.0
337
2512
A02BA04
ATC
nizatidine; systemic
2.3
8.0
68
301
M01AC01
ATC
piroxicam; systemic, rectal
1.9
7.9
113
621
AA1AD
NOMESCO Finland
CT of head and brain
1.7
7.9
185
1190
WX120
NOMESCO Finland
Intravenous local anesthesy of arm
7.8
7.9
17
22
WZC30
SPAT
NA
4.4
7.9
27
63
M43.1
ICD-10 Finland
Spondylolisthesis
3.1
7.8
41
136
G43.9
ICD-10 Finland
Migraine, unspecified
2.5
7.8
60
248
M01AB01
ATC
indometacin; systemic, rectal
2.5
7.8
61
257
R96
ICPC
Asthma
2.2
7.8
77
364
R03BA05
ATC
fluticasone; inhalant
1.7
7.8
158
975
TAB00
NOMESCO Finland
Lumbar puncture
2.9
7.7
46
166
R35
ICD-10 Finland
Polyuria
2.6
7.7
53
207
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.2
7.7
78
373
XFE00
NOMESCO Finland
Epicardial ultrasonography
4.2
7.6
27
65
SPAT1263
SPAT
Sampling
1.5
7.6
363
2771
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.0
7.6
95
496
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
2.1
7.6
82
403
M71.9
ICD-10 Finland
Bursopathy, unspecified
11.9
7.6
13
11
NHL50
NOMESCO Finland
Tenolysis or tenosynovectomy of foot
25.2
7.6
10
*
NC1CG
NOMESCO Finland
Elbow and forearm extensive MRI examination with high intensity magnet
25.2
7.6
10
*
R06AX22
ATC
ebastine; oral
1.7
7.6
170
1081
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
6.2
7.6
19
31
R21
ICPC
Throat symptom/complaint
1.7
7.5
179
1158
R01BA52
ATC
pseudoephedrine, combinations; oral
1.5
7.5
286
2082
M22.4
ICD-10 Finland
Chondromalacia patellae
3.4
7.5
34
102
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
3.4
7.5
34
102
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
4.5
7.5
25
57
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.7
7.4
30
82
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
7.3
123
716
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
7.3
200
1340
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
8.4
7.3
15
18
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
7.3
63
279
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
7.3
266
1909
M19.8
ICD-10 Finland
Other specified arthrosis
3.6
7.3
31
88
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.3
7.3
34
104
M76.7
ICD-10 Finland
Peroneal tendinitis
11.0
7.3
13
12
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
11.0
7.3
13
12
NCL22
NOMESCO Finland
Myotomy or tenotomy of elbow or forearm
+∞
7.3
7
*
Q66.7
ICD-10 Finland
Pes cavus
+∞
7.3
7
*
7261X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]
+∞
7.3
7
*
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.1
7.3
37
121
A07EC01
ATC
sulfasalazine; oral, rectal
2.2
7.2
70
327
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.0
7.2
41
142
WX203
NOMESCO Finland
Infraclavicular plexus blockade
4.0
7.2
27
69
L04
ICPC
Chest symptom/complaint
2.5
7.2
54
224
E66.00
ICD-10 Finland
Metabolic syndrome
2.6
7.2
51
206
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
7.1
502
4124
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.5
7.1
53
218
R07.0
ICD-10 Finland
Pain in throat
2.4
7.1
57
245
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.6
7.1
30
85
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
2.0
7.1
85
436
N04BC05
ATC
pramipexole; oral
2.4
7.1
56
238
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
7.1
76
374
NBE35
NOMESCO Finland
Transposition of ligament of shoulder, arthroscopic
10.1
7.0
13
13
Z04.9
ICD-10 Finland
Examination and observation for unspecified reason
3.0
7.0
40
139
M75
ICD-10 Finland
Shoulder lesions
3.0
7.0
40
139
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.8
7.0
28
76
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
5.0
7.0
21
43
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.2
7.0
71
341
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
5.2
7.0
20
39
M53.3
ICD-10 Finland
Sacrococcygeal disorders, not elsewhere classified
6.4
7.0
17
27
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
6.9
226
1580
R51.81
ICD-10 Finland
Facial pain NOS
4.1
6.9
25
62
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.8
6.9
42
155
R22.9
ICD-10 Finland
Localized swelling, mass and lump, unspecified
2.2
6.9
68
322
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
6.9
187
1251
N05BA01
ATC
diazepam; systemic, rectal
1.8
6.9
112
645
SPAT1153
SPAT
Removal of sutures
1.5
6.9
248
1778
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
6.8
349
2686
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
2.9
6.8
39
136
M54.8
ICD-10 Finland
Other dorsalgia
2.9
6.8
39
136
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.2
6.8
24
58
KMAK
NOMESCO Finland
NA
1.4
6.8
483
3959
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.1
6.8
77
388
M70.5
ICD-10 Finland
Other bursitis of knee
11.0
6.8
12
11
SPAT1285
SPAT
Provision of consultation response
2.5
6.8
51
211
H02BX01
ATC
methylprednisolone, combinations; systemic
2.9
6.8
39
137
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.8
6.8
111
638
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
9.4
6.8
13
14
D10
ICPC
Vomiting
2.4
6.8
54
231
S06.0
ICD-10 Finland
Concussion
2.0
6.8
83
433
N06AB10
ATC
escitalopram; oral
1.6
6.7
174
1149
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.5
6.7
258
1871
9736
FHL
Subcutaneous tumor removal in operating room or anesthesia
7.2
6.7
15
21
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
6.7
148
936
G04BD12
ATC
mirabegron; oral
2.1
6.7
76
384
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
5.0
6.7
20
41
M71.5
ICD-10 Finland
Other bursitis, not elsewhere classified
22.7
6.7
9
*
OAB50
SPAT
NA
6.5
6.6
16
25
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.5
6.6
29
85
A07AA02
ATC
nystatin; oral
2.3
6.6
58
259
JAH01
NOMESCO Finland
Laparoscopy
2.5
6.6
47
190
N02AC04
ATC
dextropropoxyphene; oral
3.4
6.6
29
86
A29
ICPC
General symptom/complaint other
1.9
6.6
89
481
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.3
6.5
31
97
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
10.1
6.5
12
12
M09AA72
ATC
quinine, combinations with psycholeptics; systemic
4.2
6.5
23
56
I80.29
ICD-10 Finland
Phlebitis and thrombophlebitis of other deep vessels of lower extremities
3.6
6.5
27
76
G57.6
ICD-10 Finland
Lesion of plantar nerve
4.0
6.5
24
61
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
3.3
6.5
30
92
R05
ICPC
Cough
1.6
6.5
183
1235
R00.2
ICD-10 Finland
Palpitations
2.1
6.5
70
346
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
5.4
6.5
18
34
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.3
6.5
58
264
WX204
NOMESCO Finland
Axillary plexus blockaced
3.4
6.5
29
87
K80
ICPC
Cardiac arrhythmia NOS
2.2
6.5
63
298
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
4.3
6.4
22
52
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.2
6.4
65
312
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.0
6.4
76
390
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
7.5
6.4
14
19
K59.0
ICD-10 Finland
Constipation
2.6
6.4
45
179
M48.9
ICD-10 Finland
Spondylopathy, unspecified
14.4
6.4
10
7
K11.2
ICD-10 Finland
Sialoadenitis
3.2
6.4
31
99
U07.2
ICD-10 Finland
COVID-19, virus not identified
1.6
6.4
160
1047
N06AA12
ATC
doxepin; systemic
2.5
6.4
46
188
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
8.2
6.3
13
16
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
8.2
6.3
13
16
C09CA06
ATC
candesartan; oral
1.6
6.3
181
1224
G50.1
ICD-10 Finland
Atypical facial pain
4.0
6.3
23
58
G56.3
ICD-10 Finland
Lesion of radial nerve
11.1
6.3
11
10
P01BA02
ATC
hydroxychloroquine; oral
2.1
6.3
68
334
Z01.2
ICD-10 Finland
Dental examination
1.4
6.3
363
2856
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
6.3
349
2725
M66.0
ICD-10 Finland
Rupture of popliteal cyst
18.1
6.3
9
5
N02AJ13
ATC
tramadol and paracetamol; systemic
4.4
6.3
21
49
H02AB04
ATC
methylprednisolone; systemic
1.7
6.2
118
712
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
6.2
63
303
R03AC13
ATC
formoterol; inhalant
2.5
6.2
45
185
C03CA01
ATC
furosemide; systemic
1.6
6.2
161
1062
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.2
6.1
29
91
J01AA07
ATC
tetracycline; systemic
1.7
6.1
141
900
J01MA01
ATC
ofloxacin; systemic
2.1
6.1
69
346
H66.9
ICD-10 Finland
Otitis media, unspecified
2.4
6.1
48
206
I87.2
ICD-10 Finland
Venous insufficiency (chronic)(peripheral)
1.9
6.1
82
443
K12.10
ICD-10 Finland
Stomatitis NOS
12.6
6.1
10
8
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
6.0
79
421
SBB10
NOMESCO Finland
Teeth copy
2.2
6.0
55
253
R01AD11
ATC
triamcinolone; nasal
2.0
6.0
77
407
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
6.1
6.0
15
25

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
359
1775
2.49
41.36
1.7
1.6
0.9
1.1
mg/l
0.75
261
1314
868
6523
2.37
34.19
5.1
3.5
10.5
11.5
mm/h
1.27
815
6022
243
1110
2.51
32.25
1.5
1.3
342.5
514.8
titre
1.58
55
217
472
2852
2.12
31.98
6.0
5.5
—
—
—
0
0
390
2258
2.10
28.98
2.3
2.0
250.7
297.1
u/l
0.17
375
2121
595
4018
2.00
28.75
6.6
5.6
0.7
0.7
%
1.13
553
3758
608
4155
1.99
28.19
6.5
5.5
2.9
2.8
%
0.82
568
3882
610
4176
1.99
28.11
6.6
5.8
8.3
8.5
%
0.83
571
3925
634
4419
1.98
27.51
6.2
5.5
0.0
0.0
e9/l
0.45
547
3837
147
569
2.82
26.93
2.3
2.3
27.4
20.7
au/ml
—
7
32
630
4402
1.96
26.91
6.2
5.5
0.6
0.6
e9/l
0.28
545
3824
647
4567
1.96
26.76
6.3
5.8
0.2
0.2
e9/l
0.73
565
4024
263
1366
2.20
25.38
1.4
1.2
7.9
13.0
u/ml
0.64
90
554
609
4264
1.92
25.24
6.3
5.4
57.5
56.8
%
0.85
570
4014
455
2897
1.95
25.10
4.7
3.2
69.2
77.2
e6/l
0.07
336
1974
615
4328
1.91
25.01
6.6
5.5
28.2
28.7
%
0.67
575
4059
637
4554
1.90
24.47
6.3
5.5
1.9
2.0
e9/l
1.26
560
4022
865
6861
2.07
24.31
7.7
7.0
76.0
77.1
u/l
0.34
824
6464
363
2160
2.00
24.21
3.8
2.7
—
—
—
0
0
314
1778
2.06
24.03
1.4
1.4
2.3
2.3
g/l
0.01
174
1141
268
1440
2.12
23.53
1.4
1.2
22.4
28.9
iu/ml
0.38
82
465
363
2210
1.94
22.33
3.8
2.7
0.3
0.5
e6/l
1.61
285
1626
385
2415
1.90
21.48
3.9
2.8
25.6
93.6
e6/l
1.61
314
1823
570
4039
1.82
21.47
6.3
6.2
1.2
1.2
mmol/l
1.07
493
3422
272
1515
2.04
21.47
3.8
3.2
189.5
454.2
ng/l
1.73
195
1103
346
2115
1.91
20.77
2.3
2.5
5484.8
6438.4
umol/l
0.13
299
1860
736
5678
1.83
20.50
5.6
3.8
382.8
1922.7
e6/l
—
8
75
688
5215
1.80
20.17
8.7
9.1
4.1
4.0
e9/l
0.39
605
4574
770
6044
1.84
20.03
5.5
3.8
—
—
—
0
0
329
2010
1.89
19.60
1.3
1.2
0.8
1.6
u/ml
1.83
72
538
517
3630
1.77
19.47
5.6
5.4
1.2
1.2
mmol/l
0.78
468
3294
349
2188
1.86
19.09
3.8
3.5
95.0
93.5
%
0.53
343
2132
1056
9354
2.69
18.53
17.1
11.3
20.0
23.3
mg/l
2.80
871
7143
468
3237
1.75
18.22
2.0
1.8
103.3
95.4
pmol/l
2.37
236
1679
274
1616
1.91
17.97
3.3
2.3
6.5
6.9
e6/l
0.11
249
1410
550
4029
1.70
17.06
9.1
8.2
0.0
0.0
e9/l
1.08
437
3319
647
4951
1.71
17.05
4.6
4.2
6.5
6.6
mmol/l
0.39
612
4577
257
1511
1.90
16.90
2.9
2.4
533.4
555.6
mosm/kgh2o
0.93
229
1289
866
7209
1.83
16.74
4.3
3.9
14.3
14.7
pmol/l
4.27
808
6603
593
4492
1.67
15.73
5.4
6.2
10.2
11.2
umol/l
2.35
567
4272
221
1266
1.92
15.61
3.1
2.6
2.6
3.3
e6/l
0.57
121
665
490
3567
1.65
14.93
4.3
4.6
36.4
36.0
g/l
0.79
437
3338
178
963
2.00
14.79
2.6
2.4
5.1
7.5
umol/l
3.07
158
834
982
8620
1.99
14.66
5.3
4.5
1.8
2.1
mu/l
0.90
927
7930
193
1081
1.94
14.50
2.0
2.0
—
—
—
0
0
169
914
2.00
14.02
1.8
1.6
—
—
—
0
0
225
1354
1.82
13.46
2.9
2.5
0.9
1.2
e6/l
0.78
124
748
557
4272
1.59
13.18
6.0
4.4
0.0
0.0
estimate
0.50
80
789
150
797
2.02
13.04
2.4
2.2
34.8
44.6
u/l
0.74
129
688
334
2270
1.67
12.89
5.9
6.6
—
—
—
0
0
553
4252
1.58
12.82
3.8
3.2
0.0
0.0
estimate
0.00
78
769
558
4320
1.57
12.41
3.9
3.2
0.0
0.0
estimate
0.29
80
764
201
1211
1.80
11.86
1.8
2.0
28.9
29.7
s
1.33
193
1170
183
1074
1.84
11.77
1.9
2.3
94.7
116.3
ug/g
0.69
146
852
191
1144
1.80
11.47
1.3
1.2
—
—
—
0
0
425
3141
1.56
11.30
8.1
7.5
1.1
1.2
inr
1.07
103
945
403
2954
1.56
11.05
3.6
3.0
32.7
33.1
ng/l
0.02
249
1809
364
2614
1.58
10.89
2.5
2.3
54.2
59.3
u/l
1.66
332
2423
83
375
2.31
10.88
2.7
2.3
—
—
—
0
0
1047
9614
2.06
10.62
17.3
12.6
139.7
139.7
mmol/l
0.18
1025
9355
391
2868
1.55
10.59
3.1
3.5
2.4
2.4
mmol/l
0.18
333
2547
79
357
2.30
10.36
1.2
1.2
—
—
—
0
0
30
79
3.87
10.26
1.4
1.2
—
—
—
0
0
1073
9965
2.25
10.22
14.5
10.7
—
—
—
0
0
471
3626
1.51
10.06
2.3
2.2
80.1
76.5
nmol/l
1.65
433
3309
284
1956
1.60
10.02
2.9
2.8
950.4
1088.3
ng/l
0.29
245
1625
334
2391
1.56
9.97
3.8
3.8
7.4
7.4
ph
0.20
45
440
476
3682
1.50
9.89
2.3
2.0
—
—
—
0
0
109
570
2.01
9.86
1.4
1.3
124.8
205.5
u/ml
0.77
102
519
1046
9648
1.99
9.75
17.6
12.8
4.0
3.9
mmol/l
0.13
1024
9366
276
1901
1.60
9.70
3.5
3.3
—
—
—
0
0
91
451
2.11
9.52
1.3
1.2
—
—
—
0
0
320
2299
1.54
9.30
4.2
3.3
—
—
—
0
0
161
981
1.75
9.03
1.2
1.3
—
—
—
0
0
511
4082
1.46
8.67
3.7
3.8
—
—
—
0
0
364
2723
1.49
8.63
2.3
2.1
—
—
—
0
0
56
239
2.41
8.38
1.1
1.1
—
—
—
0
0
900
8052
1.55
8.36
20.2
14.1
13.6
13.6
%
0.11
888
7861
44
171
2.64
8.00
1.1
1.2
—
—
—
0
0
66
309
2.21
7.99
1.2
1.0
—
—
—
0
0
43
166
2.65
7.93
1.3
1.2
8.9
12.9
e6/l
0.25
34
127
43
166
2.65
7.93
1.4
1.3
1556.1
402.4
e6/l
0.37
37
137
21
52
4.10
7.82
2.3
2.2
514.3
482.0
min
0.94
21
41
75
375
2.07
7.69
2.7
3.1
—
—
—
0
0
125
747
1.76
7.48
2.1
2.0
371.2
385.4
nmol/l
0.31
116
684
272
1968
1.50
7.43
2.1
2.0
2.8
2.9
mg/l
0.66
236
1656
39
149
2.67
7.35
1.3
1.3
—
—
—
0
0
1076
10156
2.01
7.34
11.8
9.2
27.3
26.4
u/l
0.69
1049
9815
23
64
3.65
7.32
1.1
1.1
33.1
41.7
mg/l
0.61
18
50
65
315
2.13
7.24
1.3
1.2
0.4
1.7
u/ml
—
5
23
491
3991
1.40
7.13
3.0
2.6
94.4
114.5
ug/l
2.27
465
3731
68
339
2.07
7.05
1.7
1.7
—
—
—
0
0
22
61
3.66
7.05
1.1
1.0
257.7
255.7
mg/l
0.01
17
51
116
691
1.76
7.02
1.2
1.1
—
—
—
0
0
49
214
2.35
7.01
1.5
1.4
316.3
302.9
ug/g
0.15
29
121
181
1212
1.59
6.99
2.5
2.3
13.9
13.9
umol/l
0.02
169
1117
731
6369
1.41
6.99
3.6
3.3
—
—
—
0
0
987
9118
1.60
6.94
4.5
4.0
5.9
5.8
mmol/l
0.17
920
8362
157
1019
1.63
6.90
1.4
1.4
—
—
—
0
0
971
8944
1.57
6.82
18.7
12.4
40.2
40.1
%
0.15
754
6810
19
50
3.85
6.55
1.0
1.0
—
—
—
0
0
319
2432
1.43
6.55
3.2
2.6
—
—
—
0
0
166
1106
1.59
6.54
2.6
2.3
2.4
2.4
g/l
0.43
157
1019
272
2023
1.45
6.35
4.8
4.0
—
—
—
0
0
190
1322
1.52
6.16
1.8
1.7
1132.6
1182.9
nmol/l
0.29
146
996
274
2052
1.44
6.15
2.2
2.1
—
—
—
0
0
97
573
1.76
6.05
4.0
2.8
146.7
167.8
ng/l
0.37
88
520
19
53
3.63
6.05
1.2
1.0
—
—
—
0
0
105
637
1.71
5.97
2.1
2.6
9.9
10.6
g/l
1.08
92
579
157
1061
1.56
5.80
4.5
5.3
1.0
1.0
mmol/l
0.20
146
989
77
432
1.84
5.71
2.9
3.3
5.1
5.2
kpa
0.36
70
411
151
1020
1.55
5.59
2.6
2.4
23.1
23.5
%
0.15
134
868
125
810
1.61
5.52
2.3
2.7
1.6
1.8
%
2.08
116
722
109
683
1.66
5.50
3.7
3.3
1.4
2.1
mmol/l
0.92
86
540
121
780
1.62
5.46
3.8
3.8
—
—
—
0
0
925
8538
1.44
5.41
5.8
5.0
39.3
39.0
mmol/mol
0.40
877
7963
204
1484
1.46
5.28
2.8
3.0
2.4
2.4
mmol/l
2.11
169
1318
96
592
1.68
5.16
2.7
3.7
83.8
83.8
ng/l
0.00
78
528
29
116
2.54
5.07
1.7
1.6
—
—
—
0
0
79
465
1.75
5.02
2.1
2.4
—
—
—
0
0
268
2071
1.38
4.91
4.2
4.4
—
—
—
0
0
35
156
2.28
4.86
1.7
1.6
5882.4
14345.2
e6/l
1.04
25
118
101
643
1.63
4.81
6.1
7.8
9.1
8.9
mmol/l
0.08
94
610
233
1765
1.40
4.80
1.6
1.4
21.1
21.0
nmol/l
0.02
190
1522
18
57
3.19
4.77
1.2
1.2
—
—
—
0
0
30
127
2.40
4.68
1.3
1.2
—
—
—
0
0
106
689
1.59
4.64
3.8
3.2
5.8
5.8
kpa
0.00
101
669
100
643
1.61
4.58
8.8
7.8
—
—
—
0
0
126
857
1.53
4.53
7.0
7.4
5.1
5.1
kpa
0.31
119
818
126
857
1.53
4.53
7.0
7.4
12.3
12.7
kpa
0.41
120
820
16
49
3.30
4.48
1.0
1.1
—
—
—
0
0
32
143
2.27
4.44
1.0
1.0
—
—
—
0
0
112
746
1.56
4.42
7.4
8.0
96.3
95.9
%
0.60
105
718
126
863
1.52
4.39
7.1
7.4
1.4
1.2
mmol/l
0.23
100
684
16
50
3.23
4.34
1.2
1.0
0.1
1.7
nmol/l
—
5
9
307
2466
1.33
4.33
1.7
1.6
1.4
1.4
mmol/l
0.01
270
2097
177
1302
1.43
4.29
3.2
3.3
0.8
0.8
mmol/l
0.20
168
1230
18
62
2.93
4.18
2.3
1.9
—
—
—
0
0
101
667
1.56
4.15
8.4
6.7
1.3
1.3
mmol/l
0.22
96
643
88
564
1.61
4.11
1.2
1.2
—
—
—
0
0
965
9094
1.39
3.98
4.0
3.6
1.3
1.3
mmol/l
0.03
904
8431
54
306
1.80
3.95
2.7
3.4
—
—
—
0
0
1108
10760
1.97
3.94
23.9
16.9
6.6
6.7
e9/l
0.46
1088
10446
19
70
2.74
3.93
1.4
1.2
—
—
—
0
0
1107
10749
1.95
3.90
23.8
16.9
254.7
256.2
e9/l
0.33
1088
10470
24
101
2.41
3.83
1.6
1.5
—
—
—
0
0
1107
10754
1.93
3.82
23.8
16.8
91.1
90.8
fl
2.15
1094
10600
17
60
2.86
3.80
1.4
2.5
351.7
457.3
e6/l
0.64
12
54
144
1043
1.44
3.80
1.5
1.6
—
—
—
0
0
1107
10756
1.93
3.79
23.7
16.8
30.4
30.3
pg
2.84
1094
10601
31
147
2.14
3.77
1.1
1.0
—
—
—
0
0
1107
10757
1.92
3.77
23.9
16.9
4.5
4.5
e12/l
0.94
1085
10446
43
231
1.90
3.73
1.3
1.2
—
792.5
—
0
8
42
224
1.91
3.72
2.8
3.0
—
—
—
0
0
296
2413
1.31
3.69
3.8
2.8
—
—
—
0
0
1107
10764
1.90
3.65
24.0
17.0
136.1
135.9
g/l
0.17
1094
10608
29
137
2.15
3.57
2.1
3.3
—
—
—
0
0
36
185
1.98
3.56
2.9
2.3
80.9
110.2
ug/min
0.26
30
118
996
9476
1.40
3.53
4.6
4.1
4.8
4.8
mmol/l
0.37
952
8873
264
2131
1.31
3.52
4.8
4.4
1.7
2.5
ug/l
2.34
227
1909
10
26
3.87
3.52
1.5
5.1
—
—
—
0
0
93
630
1.52
3.44
3.7
4.3
0.6
0.7
%
0.02
17
145
18
70
2.60
3.39
1.8
1.6
70.4
53.4
%
1.57
11
46
101
699
1.49
3.38
3.6
4.2
1.1
0.9
%
0.18
22
190
225
1787
1.32
3.36
4.1
3.6
1.0
1.0
kg/l
0.52
64
265
96
659
1.50
3.34
3.7
4.3
0.0
0.1
%
0.82
20
175
122
879
1.43
3.32
16.2
20.0
1.2
1.2
inr
0.26
14
139
86
581
1.52
3.24
2.1
2.9
62.6
69.9
e9/l
1.46
63
435
22
97
2.29
3.21
4.7
6.0
10.5
11.4
mg/l
0.38
17
92
78
518
1.54
3.18
3.2
2.6
—
—
—
0
0
288
2381
1.28
3.18
3.1
3.2
270.3
384.2
mg/l
0.21
180
1483
35
187
1.90
3.13
1.1
1.1
0.4
2.5
u/ml
1.27
14
71
988
9424
1.36
3.12
4.6
4.0
1.5
1.5
mmol/l
0.56
937
8769
31
159
1.98
3.11
1.1
1.1
6.5
6.7
u/ml
0.02
15
78
90
621
1.49
3.08
1.6
2.2
7.6
7.7
ug/l
0.01
74
555
88
606
1.49
3.04
1.6
1.4
—
—
—
0
0
7
12
5.86
3.02
1.3
1.0
—
—
—
0
0
50
302
1.69
3.00
1.5
1.9
1.2
1.6
g/l
3.20
45
259
222
1787
1.30
3.00
1.8
1.8
—
—
—
0
0
162
1250
1.34
2.95
2.9
2.7
0.6
0.8
ug/l
1.34
102
759
44
258
1.73
2.94
2.5
3.7
24.3
25.0
mmol/l
0.98
38
241
19
82
2.34
2.92
1.4
2.4
1.4
1.1
e9/l
—
6
48
41
236
1.76
2.92
1.2
1.1
—
—
—
0
0
30
157
1.94
2.87
1.1
1.1
0.6
1.1
u/ml
0.68
12
63
155
1195
1.34
2.84
1.2
1.3
—
—
—
0
0
84
582
1.48
2.83
2.1
2.1
12.8
13.1
nmol/l
0.10
75
519
18
77
2.36
2.82
1.4
1.4
—
—
—
0
0
8
18
4.47
2.79
1.0
2.0
—
—
—
0
0
41
240
1.73
2.77
1.2
1.1
—
—
—
0
0
1003
9625
1.34
2.74
5.1
4.4
2.9
2.9
mmol/l
0.07
949
8945
14
54
2.61
2.71
2.6
2.5
0.4
2.0
u/field
—
5
27
297
2511
1.25
2.67
3.5
3.8
11.9
8.5
mg/mmol
0.47
187
1563
23
113
2.06
2.63
1.2
1.3
—
—
—
0
0
102
750
1.40
2.52
2.2
2.2
0.2
0.2
g/l
0.34
94
710
16
69
2.34
2.49
1.3
1.0
—
—
—
0
0
42
256
1.67
2.48
2.5
2.7
—
—
—
0
0
19
89
2.15
2.45
1.7
1.2
—
—
—
0
0
28
152
1.86
2.44
1.1
1.0
0.2
4.5
u/ml
—
7
38
117
886
1.36
2.43
1.5
1.4
—
—
—
0
0
25
131
1.93
2.42
1.8
2.3
16.9
16.4
%
0.45
16
75
9
27
3.35
2.39
1.0
6.9
—
—
—
0
0
29
162
1.81
2.32
1.8
2.0
129.8
132.0
g/l
0.22
24
123
73
514
1.45
2.31
1.5
1.7
1.2
1.5
g/l
0.97
66
473
14
59
2.39
2.29
1.8
1.4
150967.8
9828.6
e6/l
—
9
43
34
202
1.70
2.23
3.0
3.4
—
—
—
0
0
28
157
1.80
2.23
4.1
2.8
1.5
1.6
mmol/l
0.39
28
152
91
672
1.38
2.22
1.3
1.2
223.0
145.6
iu/ml
0.55
25
256
85
1140
0.73
2.17
1.3
1.4
—
—
—
0
0
26
144
1.82
2.16
1.2
1.2
4.4
3.9
u/ml
0.09
14
58
72
515
1.42
2.12
1.4
1.4
28.9
29.7
iu/l
0.07
66
443
177
1449
1.26
2.10
1.5
1.6
—
—
—
0
0
8
25
3.22
2.09
1.0
1.4
—
—
—
0
0
30
176
1.72
2.07
1.1
1.4
—
—
—
0
0
18
89
2.04
2.06
2.6
3.5
—
—
—
0
0
7
20
3.51
2.05
1.0
1.1
—
—
—
0
0
8
26
3.09
2.01
1.1
1.1
—
273.8
—
0
5
112
869
1.32
2.01
3.4
4.6
2.6
27.8
ug/l
1.78
93
700
297
2583
1.20
1.98
3.0
3.1
7.6
7.6
mmol/l
0.05
249
2211
46
305
1.53
1.98
3.3
5.8
1.7
1.6
%
0.30
41
285
14
64
2.20
1.95
1.3
1.3
—
—
—
0
0
45
299
1.53
1.92
1.2
1.2
—
—
—
0
0
129
1027
1.29
1.92
1.3
1.4
—
—
—
0
0
28
165
1.71
1.92
2.0
2.0
—
—
—
0
0
34
213
1.61
1.87
2.4
3.4
1.8
1.1
ratio
—
5
17
6
17
3.54
1.84
1.7
1.3
—
—
—
0
0
12
53
2.28
1.81
1.2
1.0
—
—
—
0
0
26
154
1.70
1.77
1.9
2.4
—
—
—
0
0
24
139
1.74
1.76
1.1
1.0
4.2
3.5
u/ml
—
8
47
29
179
1.64
1.71
1.2
1.2
248.1
237.1
u/ml
0.09
19
105
48
333
1.46
1.70
2.3
2.3
0.7
0.7
%
0.15
48
324
22
126
1.76
1.68
1.1
1.0
3.3
4.5
u/ml
—
10
46
89
689
1.32
1.66
1.3
1.5
—
—
—
0
0
24
142
1.70
1.65
1.3
1.2
—
—
—
0
0
14
69
2.04
1.65
1.2
2.1
916.0
743.4
e6/l
—
8
31
19
105
1.82
1.63
1.2
1.3
—
—
nmol/l
—
0
0
48
337
1.44
1.61
1.5
1.9
20.6
20.9
s
0.28
42
295
7
26
2.70
1.58
1.0
1.2
—
—
—
0
0
26
161
1.63
1.53
1.1
1.3
96.9
113.9
u/ml
—
7
26
77
593
1.32
1.50
1.9
2.9
4.3
4.0
e9/l
0.34
58
491
27
171
1.59
1.47
3.5
3.3
27.5
25.9
mg/l
0.08
18
108
16
87
1.85
1.46
1.0
1.1
—
—
—
0
0
199
1719
1.19
1.43
1.6
1.6
438.2
25137044.7
pmol/l
1.50
165
1464
59
441
1.36
1.42
1.0
1.1
—
—
—
0
0
26
167
1.57
1.35
1.2
1.2
—
—
—
0
0
63
480
1.33
1.35
2.6
4.8
—
—
—
0
0
13
68
1.92
1.33
1.2
1.3
—
—
—
0
0
22
136
1.63
1.33
3.5
2.3
—
—
—
0
0
25
161
1.57
1.29
1.1
1.2
—
—
—
0
0
25
161
1.57
1.29
3.1
2.9
3.8
4.0
e9/l
0.23
25
161
5
18
2.79
1.28
1.2
1.7
—
—
—
0
0
55
414
1.35
1.28
8.1
10.6
—
—
—
0
0
10
48
2.09
1.28
1.1
1.3
—
—
—
0
0
25
163
1.55
1.23
1.6
1.5
—
—
—
0
0
11
56
1.97
1.22
1.2
1.3
—
—
—
0
0
76
604
1.28
1.22
3.1
3.3
4.4
4.6
pmol/l
0.75
66
540
5
20
2.51
1.15
1.0
1.0
—
—
—
0
0
16
95
1.69
1.14
1.4
1.1
—
—
—
0
0
12
65
1.86
1.13
1.5
2.9
—
—
—
0
0
79
639
1.25
1.11
3.6
4.0
0.6
0.6
%
0.03
16
140
46
346
1.34
1.11
1.8
1.8
—
—
—
0
0
15
89
1.69
1.08
2.3
2.5
—
—
—
0
0
25
169
1.49
1.08
3.2
3.1
53.4
57.2
%
0.66
25
169
7
33
2.13
1.05
1.4
1.8
—
—
—
0
0
42
317
1.34
1.01
3.2
3.7
13.7
1228.1
u/ml
1.42
37
284
12
68
1.77
1.00
2.3
1.4
0.3
1.1
u/ml
—
6
29
13
76
1.72
0.99
3.5
4.8
—
—
—
0
0
5
23
2.18
0.98
1.0
1.3
—
—
—
0
0
24
166
1.46
0.95
1.8
3.8
—
—
—
0
0
11
62
1.78
0.94
1.0
1.1
—
—
—
0
0
6
29
2.07
0.89
1.7
1.2
—
—
—
0
0
78
650
1.21
0.88
4.2
3.4
1.2
1.2
mmol/l
1.09
69
556
15
95
1.59
0.87
2.0
2.4
—
—
—
0
0
20
137
1.47
0.84
3.1
3.7
4.0
2.3
mmol/l
1.50
12
87
95
812
1.19
0.83
1.4
1.4
—
—
—
0
0
43
337
1.29
0.83
1.3
1.3
274.0
249.8
miu/ml
0.22
27
166
6
32
1.88
0.82
2.2
2.2
—
—
—
0
0
21
147
1.44
0.80
1.5
1.6
—
—
—
0
0
0
25
0.00
0.79
0.0
1.0
—
—
—
0
0
8
48
1.67
0.79
1.0
1.6
—
—
—
0
0
11
66
1.67
0.79
1.5
1.5
—
—
—
0
0
13
82
1.59
0.78
1.4
1.1
—
—
—
0
0
9
54
1.67
0.74
8.2
6.5
—
—
—
0
0
21
288
0.72
0.73
13.1
7.8
—
—
—
0
0
20
142
1.42
0.72
4.3
2.7
—
—
—
0
0
18
253
0.71
0.72
1.6
1.2
—
—
—
0
0
9
56
1.61
0.72
1.0
1.5
—
—
—
0
0
11
68
1.62
0.72
3.2
2.4
—
—
—
0
0
7
40
1.75
0.71
1.0
1.1
176.7
228.6
iu/ml
—
7
40
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
7
41
1.71
0.70
1.4
2.0
—
—
—
0
0
5
29
1.73
0.64
1.8
1.0
—
—
—
0
0
5
29
1.73
0.64
4.4
2.6
—
—
—
0
0
109
967
1.14
0.63
1.6
1.6
—
—
—
0
0
11
71
1.55
0.62
1.2
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.2
—
21.9
—
0
14
6
36
1.67
0.56
1.3
1.3
—
—
—
0
0
42
349
1.21
0.54
2.1
2.1
4459.0
3326.1
u/l
0.14
13
146
6
38
1.58
0.54
1.2
1.1
—
11.3
—
0
8
6
41
1.47
0.50
1.0
1.3
264.3
599.0
u/l
—
6
36
6
41
1.47
0.50
1.3
1.1
1459.3
1796.9
miu/ml
—
6
41
55
635
0.86
0.49
1.4
1.8
—
—
—
0
0
7
47
1.49
0.47
1.3
1.1
—
—
—
0
0
14
102
1.38
0.47
1.4
1.4
—
—
—
0
0
14
103
1.36
0.45
1.3
1.2
—
—
—
0
0
14
103
1.36
0.45
1.1
1.6
—
—
—
0
0
14
103
1.36
0.45
1.1
1.6
—
—
—
0
0
14
103
1.36
0.45
1.1
1.6
—
—
—
0
0
14
103
1.36
0.45
1.1
1.6
—
—
—
0
0
283
2689
1.07
0.43
1.4
1.5
—
—
—
0
0
8
57
1.41
0.42
1.3
1.5
9.3
11.3
%
—
8
57
30
249
1.21
0.42
1.5
1.5
15.0
9.8
u/l
0.46
22
207
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.0
—
—
—
0
0
83
749
1.12
0.41
3.6
3.2
—
—
—
0
0
8
60
1.34
0.40
2.0
3.4
—
—
—
0
0
11
81
1.36
0.36
2.0
3.2
—
—
—
0
0
6
42
1.43
0.35
3.0
2.7
384.0
1409.9
u/ml
—
6
42
13
99
1.32
0.35
7.1
2.8
—
—
—
0
0
9
126
0.71
0.35
1.0
1.1
—
—
—
0
0
6
46
1.31
0.33
1.2
1.2
105.8
144.6
nmol/l
—
6
46
31
266
1.17
0.32
1.4
2.0
4.4
5.0
iu/l
—
10
107
231
2206
1.06
0.32
4.0
3.5
0.0
0.0
estimate
0.80
78
780
10
75
1.34
0.30
1.1
1.4
14.7
12.1
mmol/l
—
5
19
26
222
1.18
0.29
1.5
1.4
—
—
—
0
0
8
109
0.73
0.29
2.6
2.5
—
—
—
0
0
30
344
0.87
0.28
1.9
1.9
—
—
—
0
0
26
223
1.17
0.28
1.5
1.4
—
—
—
0
0
10
76
1.32
0.28
1.1
1.2
—
—
—
0
0
18
149
1.21
0.28
1.6
1.9
—
—
—
0
0
23
269
0.85
0.28
3.4
3.9
—
—
—
0
0
5
75
0.67
0.26
1.6
2.2
—
—
—
0
0
9
77
1.17
0.24
1.8
1.9
89.3
90.0
%
—
9
77
31
275
1.13
0.23
2.2
4.0
0.4
0.2
g/l
0.34
16
127
5
40
1.25
0.22
1.2
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
7.9
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
10.4
—
—
—
0
0
0
11
0.00
0.21
0.0
3.2
—
—
—
0
0
0
10
0.00
0.21
0.0
4.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
257.6
—
0
5
0
12
0.00
0.21
0.0
1.5
—
—
—
0
0
8
103
0.78
0.21
1.3
1.2
—
—
—
0
0
26
230
1.13
0.20
1.5
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
2.0
—
—
—
0
0
0
14
0.00
0.20
0.0
4.1
—
—
—
0
0
7
59
1.19
0.18
1.1
1.1
—
—
—
0
0
7
63
1.11
0.17
2.1
1.3
—
—
—
0
0
64
602
1.07
0.17
2.9
3.4
—
—
—
0
0
17
148
1.15
0.17
1.9
2.5
—
—
—
0
0
35
377
0.93
0.13
1.8
1.9
—
—
—
0
0
14
123
1.14
0.12
1.1
1.3
—
—
—
0
0
35
374
0.93
0.11
1.8
1.9
—
—
—
0
0
113
1095
1.04
0.11
1.8
1.7
—
—
—
0
0
35
373
0.94
0.11
1.6
1.8
—
—
—
0
0
35
373
0.94
0.11
1.8
1.9
—
—
—
0
0
14
155
0.90
0.09
3.4
3.6
14.6
1949.3
u/ml
0.66
14
146
5
62
0.81
0.08
1.0
1.1
—
—
—
0
0
11
98
1.12
0.07
2.7
2.6
34.2
32.5
pg
0.98
11
98
70
722
0.97
0.07
1.3
1.4
—
—
—
0
0
7
80
0.87
0.07
1.6
1.5
0.9
1.0
g/l
—
7
80
13
142
0.91
0.06
1.5
1.5
—
—
—
0
0
10
111
0.90
0.06
2.0
1.6
12.7
3.9
ug/l
—
10
102
26
247
1.05
0.05
2.1
2.6
—
—
—
0
0
27
283
0.95
0.05
2.0
1.9
—
—
—
0
0
10
109
0.92
0.04
2.0
1.3
—
—
—
0
0
19
200
0.95
0.03
1.4
1.1
—
—
—
0
0
378
3793
0.99
0.02
3.0
2.6
—
—
—
0
0
17
164
1.04
0.00
1.1
1.1
182.1
55.9
iu/ml
—
5
42
15
148
1.01
0.00
1.8
1.6
—
—
—
0
0
18
182
0.99
0.00
1.0
1.1
—
—
—
0
0
13
129
1.01
0.00
1.2
1.2
—
—
—
0
0
18
183
0.98
0.00
1.0
1.1
—
—
—
0
0
5
56
0.89
0.00
1.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
7
0.00
0.00
0.0
1.6
—
—
—
0
0
0
8
0.00
0.00
0.0
4.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.7
—
14.7
—
0
9
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
173.4
—
0
5
0
7
0.00
0.00
0.0
1.7
—
15.8
—
0
7
0
7
0.00
0.00
0.0
1.6
—
257.3
—
0
7
0
6
0.00
0.00
0.0
2.7
—
3.0
—
0
6
0
9
0.00
0.00
0.0
1.4
—
33.1
—
0
9
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_OVERUSENAS and mortality.

Females

Parameter HR [95% CI] p-value
M13_OVERUSENAS 1.099 [0.95, 1.27] 0.192
Birth year 1.001 [0.99, 1.01] 0.813

During the follow-up period (1.1.1998 — 31.12.2019), 296 out of 3326 females with M13_OVERUSENAS died.

Males

Parameter HR [95% CI] p-value
M13_OVERUSENAS 1.009 [0.86, 1.19] 0.91
Birth year 0.988 [0.98, 1.0] 0.011

During the follow-up period (1.1.1998 — 31.12.2019), 216 out of 2232 males with M13_OVERUSENAS died.

Mortality risk

Mortality risk for people of age

years, who have M13_OVERUSENAS.

N-year risk Females Males
1 0.119% 0.23%
5 0.688% 1.344%
10 1.744% 3.272%
15 3.526% 6.085%
20 6.667% 10.218%

Relationships between endpoints

Index endpoint: M13_OVERUSENAS – Other/unspecified soft tissue disorders related to use, overuse and pressure

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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