glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
4436 |
4. Check minimum number of eventsNone |
4436 |
5. Include endpointsNone |
4436 |
6. Filter based on genotype QC (FinnGen only) |
4436 |
Control definitions (FinnGen only)
- Control exclude
- H7_GLAUCOMA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- H401
- Name in latin
- Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis
Similar endpoints
↥List of similar endpoints to
Glaucoma, exfoliation
based on the number of shared cases.
Similar with more cases:
- Primary open-angle glaucoma
- Glaucoma
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 50095 | 32712 | 16908 |
| Only index persons | 38107 | 25566 | 12541 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.78 | 0.94 | 0.47 |
| Only index persons | 0.79 | 0.94 | 0.48 |
| Median age at first event (years) | |||
| Whole population | 74.18 | 74.76 | 73.11 |
| Only index persons | 73.97 | 74.56 | 72.78 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 4436 | 2498 | 1938 |
| Unadjusted period prevalence (%) | 0.85 | 0.85 | 0.85 |
| Median age at first event (years) | 72.48 | 72.27 | 72.75 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 3958
- Matched controls
- 39578
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
637.1
323.0
1411
35
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
292.6
323.0
1218
60
S01EE03
ATC
bimatoprost; ophthalmic
88.8
323.0
797
112
S01EC01
ATC
acetazolamide; systemic
67.4
323.0
850
160
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.8
323.0
2715
14465
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
37.6
323.0
550
169
XCW99
NOMESCO Finland
Other investigative procedure of eye
6.0
323.0
1153
2518
H40.0
ICD-10 Finland
Glaucoma suspect
318.6
323.0
1291
60
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
2418.5
323.0
1167
7
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
6.9
323.0
964
1754
S01EC54
ATC
brinzolamide, combinations; ophthalmic
227.6
323.0
498
25
XCH00
NOMESCO Finland
Eye pressure measurement
13.8
323.0
633
538
S01EC04
ATC
brinzolamide; ophthalmic
142.0
323.0
1526
174
S01ED51
ATC
timolol, combinations; ophthalmic
140.0
323.0
2801
671
S01EC03
ATC
dorzolamide; ophthalmic
109.2
323.0
618
67
H40.9
ICD-10 Finland
Glaucoma, unspecified
190.6
323.0
456
27
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
4503599627370496.0
323.0
3849
10
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
75.0
323.0
393
58
Z96.1
ICD-10 Finland
Presence of intraocular lens
5.9
323.0
1729
4573
S01EX03
ATC
NA
78.7
323.0
903
148
S01EE05
ATC
tafluprost; ophthalmic
61.9
323.0
975
208
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
1265.5
323.0
347
*
S01ED01
ATC
timolol; ophthalmic
46.3
323.0
1195
366
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
+∞
323.0
431
*
XCK00
NOMESCO Finland
Perimetry
33.7
323.0
1521
719
CHD00
NOMESCO Finland
Laser trabeculoplasty
1478.5
323.0
726
6
S01EE01
ATC
latanoprost; ophthalmic
79.3
323.0
2129
573
114
Kela drug reimbursment
Glaucoma
331.9
323.0
3446
784
S01EE04
ATC
travoprost; ophthalmic
54.9
323.0
680
149
CHC05
NOMESCO Finland
Iridotomy
94.8
313.3
346
40
CS494
NOMESCO Finland
Other visual field testing
34.8
308.2
405
129
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
45.2
307.1
381
93
Z01.0
ICD-10 Finland
Examination of eyes and vision
4.7
291.4
1191
3331
WX140
NOMESCO Finland
Parabulbar anesthesy
9.3
288.1
642
808
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.3
278.6
2427
12712
S01ED02
ATC
betaxolol; ophthalmic
56.7
268.2
319
61
H40.11
ICD-10 Finland
Low pressure glaucoma
154.2
259.3
273
19
CHD35
NOMESCO Finland
Laser goniopuncture
2494.1
255.8
245
*
S01EB01
ATC
pilocarpine; ophthalmic
75.8
254.1
289
41
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
+∞
252.8
240
*
H25.1
ICD-10 Finland
Senile nuclear cataract
3.2
252.1
2283
11937
3651B
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA CAPSULARE (AVOKULMA)]
+∞
235.8
224
*
XCK10
NOMESCO Finland
Photography of fundus of eye
4.7
235.0
915
2367
H40
ICD-10 Finland
Glaucoma
41.8
207.9
262
67
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
97.5
200.5
221
24
XCH05
NOMESCO Finland
Eye pressure longterm registration
193.3
194.9
202
11
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
191.3
2288
13295
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
+∞
183.8
175
*
CHD99
NOMESCO Finland
Other filtering operation
+∞
173.2
165
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
5.7
172.2
537
1056
S01EA03
ATC
apraclonidine; ophthalmic
27.1
170.2
238
93
S01EA02
ATC
dipivefrine; ophthalmic
221.0
144.9
149
7
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
81.8
139.4
157
20
CFW99
NOMESCO Finland
Other operation on conjunctiva
659.2
130.3
128
*
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.9
128.1
916
3682
3651A
ICD-9 Finland
Glaucoma, Open-angle glaucoma[GLAUCOMA SIMPLEX (AVOKULMA)]
+∞
120.4
115
*
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
+∞
118.3
113
*
H40.22
ICD-10 Finland
Chronic glaucoma with closed ventricular angle
+∞
117.2
112
*
ZXC20
NOMESCO Finland
Use of chemical agents
6.7
100.8
271
431
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
6.2
95.0
269
458
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
9.2
92.7
201
229
CJB10
NOMESCO Finland
Laser discission of secondary cataract
2.7
90.8
700
2880
H40.19
ICD-10 Finland
Other primary glaucoma with open ventricular angle
+∞
85.7
82
*
F93
ICPC
Glaucoma
63.4
85.0
99
16
H26.4
ICD-10 Finland
After-cataract
2.4
75.4
735
3409
H34.8
ICD-10 Finland
Other retinal vascular occlusions
5.6
71.3
217
403
H40.1
ICD-10 Finland
Primary open-angle glaucoma
89.6
71.2
79
9
3708
FHL
Trabeculectomy or equivalent
+∞
67.9
65
*
H40.20
ICD-10 Finland
Acute glaucoma with closed ventricular angle
+∞
67.9
65
*
ZXA05
NOMESCO Finland
Left side
1.9
67.3
1294
7997
SPAT1009
SPAT
Measurement of intraocular pressure
8.7
67.0
149
177
37512
ICD-8 Finland
Glaucoma, Chronicum capsulare
+∞
66.8
64
*
H40.8
ICD-10 Finland
Other glaucoma
337.6
66.7
67
*
H25.8
ICD-10 Finland
Other senile cataract
2.1
63.2
837
4445
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
63.0
462
1815
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
16.4
61.9
101
63
CS2P4
NOMESCO Finland
Optic nerve head imaging
57.1
61.9
73
13
H20.1
ICD-10 Finland
Chronic iridocyclitis
14.8
59.0
100
69
H40.12
ICD-10 Finland
Pigmentary glaucoma
+∞
56.4
54
*
37510
ICD-8 Finland
Glaucoma, Chronicum simplex
+∞
56.4
54
*
3650A
ICD-9 Finland
Glaucoma, Borderline glaucoma [glaucoma suspect][SUSPICIO GLAUCOMATIS (AVOKULMA)]
+∞
54.3
52
*
H25.0
ICD-10 Finland
Senile incipient cataract
2.7
53.2
411
1657
S01BC03
ATC
diclofenac; ophthalmic
4.4
51.4
196
464
H27.1
ICD-10 Finland
Dislocation of lens
14.0
51.3
89
65
CHD10
NOMESCO Finland
Trabeculectomy
+∞
51.1
49
*
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
6.4
45.9
125
202
S01FA01
ATC
atropine; ophthalmic
11.7
45.8
86
75
CK2P4
NOMESCO Finland
Optic nerve head light layer imaging (OCT)
121.4
44.8
48
*
ZXA00
NOMESCO Finland
Right side
1.7
44.6
1265
8597
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
14.3
42.6
73
52
TCG20
NOMESCO Finland
Laser suture lysis in cornea or sclera
+∞
41.7
40
*
XCW10
NOMESCO Finland
Assessment of vision
15.8
40.9
67
43
A98
ICPC
Health maint/preventive medicine
1.7
39.4
3281
29123
CFB00
NOMESCO Finland
Suture of conjunctiva
47.5
38.8
47
10
H44.5
ICD-10 Finland
Degenerated conditions of globe
72.6
38.0
43
6
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
2.4
36.8
327
1416
CHB99
NOMESCO Finland
Other operation on anterior chamber and anterior chamber angle
131.2
36.7
39
*
H40.3
ICD-10 Finland
Glaucoma secondary to eye trauma
+∞
36.5
35
*
H16.0
ICD-10 Finland
Corneal ulcer
3.4
35.8
184
565
H21.0
ICD-10 Finland
Hyphaema
18.6
35.7
55
30
37597
ICD-8 Finland
Glaucoma, Suspicio glaucomatis
+∞
35.5
34
*
ZXA10
NOMESCO Finland
Bilateral
1.7
35.2
856
5492
S01EX
ATC
Other antiglaucoma preparations
+∞
32.3
31
*
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
3.5
32.3
155
451
S01BC05
ATC
ketorolac; ophthalmic
2.3
32.0
303
1350
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
+∞
31.3
30
*
CHC03
NOMESCO Finland
Laser iridoplasty
+∞
31.3
30
*
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
8.4
31.1
69
83
CKD60
NOMESCO Finland
Anterior vitrectomy
5.5
30.7
93
173
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
17.0
29.7
47
28
CHF15
NOMESCO Finland
Cryotherapy of ciliary body
294.0
28.8
29
*
WX142
NOMESCO Finland
Sub-tenon anesthesy
11.7
27.6
51
44
F43
ICPC
Eye, Other diagnostic procedure
4.6
27.3
96
211
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
5.2
27.2
86
169
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
9.4
27.1
56
60
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
3.2
26.1
144
467
CWD00
NOMESCO Finland
Reoperation for superficial heamorrhage in eye and adjacent structures
135.8
25.6
27
*
H18.1
ICD-10 Finland
Bullous keratopathy
12.6
25.3
45
36
F38
ICPC
Eye, Other laboratory test NEC
11.3
25.1
47
42
H31.4
ICD-10 Finland
Choroidal detachment
70.3
24.8
28
*
WX002
NOMESCO Finland
Sedation and analgesia
1.6
24.7
790
5388
S01EX05
ATC
netarsudil; ophthalmic
+∞
24.0
23
*
CA1ME
NOMESCO Finland
Ultrasound oculometry
5.9
23.6
67
116
H27.8
ICD-10 Finland
Other specified disorders of lens
9.1
22.5
47
52
TCG10
NOMESCO Finland
Removal of sutures from cornea
7.3
21.7
52
72
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
2.4
20.1
182
793
CKC12
NOMESCO Finland
Photocoagulation of retina
2.6
19.9
153
611
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
19.5
1517
12290
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
11.4
18.4
34
30
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
10.7
18.4
35
33
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
20.1
17.7
26
13
XCD20
NOMESCO Finland
Photoangiography of eye
2.7
16.9
113
419
CFD10
NOMESCO Finland
Repair of conjunctiva
35.2
16.7
21
6
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
3.6
16.5
75
213
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
1.7
16.2
330
1977
SPAT1312
SPAT
General health counselling
1.4
15.9
1018
7917
H35.36
ICD-10 Finland
Macular cyst
5.4
15.8
47
88
SPAT1325
SPAT
Vaccination
1.3
15.6
1428
11751
H01.0
ICD-10 Finland
Blepharitis
2.2
15.6
155
712
WX110
NOMESCO Finland
Local anesthesy
1.3
15.1
1961
16950
CKC20
NOMESCO Finland
Cryopexy of undetached retina
9.4
14.4
29
31
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
2.2
14.3
146
677
H26.2
ICD-10 Finland
Complicated cataract
3.8
14.2
59
156
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
30.1
13.9
18
6
XCD10
NOMESCO Finland
Electrophysiological examination of eye
2.4
13.7
118
507
CHC10
NOMESCO Finland
Peripheral iridectomy
+∞
13.5
13
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
13.5
1273
10461
S01FA04
ATC
cyclopentolate; ophthalmic
3.6
13.4
59
164
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
25.8
13.3
18
7
CJF15
NOMESCO Finland
Secondary implantation of skleral fixed artificial lens in posterior chamber
11.5
13.3
24
21
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
5.4
13.3
39
73
SPAT1301
SPAT
No procedures
1.3
13.2
1192
9730
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
1.7
13.2
260
1543
SPAT1263
SPAT
Sampling
1.3
13.2
1459
12256
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
14.1
12.7
21
15
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.4
12.6
827
6421
CHB30
NOMESCO Finland
Goniotomy
+∞
12.5
12
*
37520
ICD-8 Finland
Glaucoma, Secondary
+∞
12.5
12
*
S01EB02
ATC
carbachol; ophthalmic
+∞
12.5
12
*
F99
ICPC
Eye/adnexa disease other
4.6
12.4
42
92
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
12.4
1090
8845
J01DB01
ATC
cefalexin; oral
1.3
12.4
2689
24583
S01AD03
ATC
aciclovir; ophthalmic
2.1
12.2
143
707
CHW99
NOMESCO Finland
Other operation on anterior chamber, anterior chamber angle, iris or ciliary body
37.6
12.2
15
*
Z94.7
ICD-10 Finland
Corneal transplant status
6.7
12.2
30
45
S01GX01
ATC
cromoglicic acid; ophthalmic
1.5
12.0
454
3175
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
12.0
1343
11266
N02BE01
ATC
paracetamol; systemic, rectal
1.3
11.5
3120
29207
CGG60
NOMESCO Finland
Reinforcement of sclera using graft
+∞
11.5
11
*
3656
FHL
Combined cataract glaucoma surgery
+∞
11.5
11
*
H40.29
ICD-10 Finland
Other [primary] glaucoma with closed ventricular angle
+∞
11.5
11
*
CKC15
NOMESCO Finland
Panretinal photocoagulation
3.7
11.4
48
130
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
11.3
1822
15961
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
2.0
11.2
138
697
F29
ICPC
Eye symptom/complaint other
1.7
11.1
247
1519
CG2T4
NOMESCO Finland
Topography assessment of cornea
4.2
11.1
41
99
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
1.9
11.0
149
780
CJE15
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
2.9
10.8
65
229
H54.4
ICD-10 Finland
Blindness, monocular
8.0
10.6
23
29
H16.9
ICD-10 Finland
Keratitis, unspecified
3.1
10.5
56
183
H57.1
ICD-10 Finland
Ocular pain
2.4
10.5
87
368
3702
FHL
Trabeculotomy
+∞
10.4
10
*
H18.2
ICD-10 Finland
Other corneal oedema
7.7
10.4
23
30
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
4.4
10.1
35
80
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
10.0
1319
11224
H20.8
ICD-10 Finland
Other iridocyclitis
10.0
10.0
19
19
H43.1
ICD-10 Finland
Vitreous haemorrhage
2.3
9.8
89
394
H25.2
ICD-10 Finland
Senile cataract, morgagnian type
3.6
9.7
42
118
CWW99
NOMESCO Finland
Other reoperation on eye and adjacent structures
55.1
9.6
11
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
7.8
9.6
21
27
R42
ICD-10 Finland
Dizziness and giddiness
1.3
9.5
893
7265
S01BA09
ATC
clobetasone; ophthalmic
11.4
9.5
17
15
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.3
9.5
792
6343
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
6.0
9.5
25
42
H52.1
ICD-10 Finland
Myopia
2.9
9.4
55
191
SPAT1310
SPAT
Counselling related to known health issue
1.3
9.4
1015
8412
H27.0
ICD-10 Finland
Aphakia
6.6
9.4
23
35
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
2.8
9.4
57
204
H40.21
ICD-10 Finland
Intermittent glaucoma with closed ventricular angle
+∞
9.4
9
*
CHC00
NOMESCO Finland
Iridotomy
+∞
9.4
9
*
3652B
ICD-9 Finland
Glaucoma, Primary angle-closure glaucoma[KROONINEN AHDASKULMAGLAUKOOMA]
+∞
9.4
9
*
CA1TM
NOMESCO Finland
Calculation of intraocular lens power
2.2
9.0
84
379
S18
ICPC
Laceration/cut
1.2
8.9
1412
12234
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
8.8
991
8244
CGG45
NOMESCO Finland
Full thickness transplantation of cornea using homograft
10.7
8.8
16
15
H3603, E103
ICD-10 Finland
NA
4.6
8.6
28
61
SPAT1153
SPAT
Removal of sutures
1.3
8.5
1085
9159
S01XA18
ATC
ciclosporin; ophthalmic
4.9
8.5
26
53
SPAT1053
SPAT
Memory test
1.3
8.5
774
6266
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
8.4
1060
8935
TCA15
NOMESCO Finland
Retrobulbar therapeutic injection into orbit
90.2
8.4
9
*
CHD60
NOMESCO Finland
Deep sclerectomy without implant
90.2
8.4
9
*
3703
FHL
Laser operation on ventricular angle under general anesthesia
+∞
8.3
8
*
3656X
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA SECUNDARIA ALIA SEU NUD]
+∞
8.3
8
*
CHD30
NOMESCO Finland
Laser trabeculectomy
+∞
8.3
8
*
CFW10
NOMESCO Finland
Conjunctival manipulation with a needle (needling)
+∞
8.3
8
*
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
8.3
181
1111
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
8.2
1551
13653
SDA01
NOMESCO Finland
Simple parodonthologic therapy
1.3
8.2
579
4515
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
14.5
8.2
13
9
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.3
8.2
551
4271
SDA02
NOMESCO Finland
Parodonthologic therapy
1.3
8.1
792
6465
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
2.1
8.1
87
417
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
3.4
8.0
37
111
H04.5
ICD-10 Finland
Stenosis and insufficiency of lacrimal passages
2.2
7.8
78
365
CJF20
NOMESCO Finland
Removal of artificial lens
15.0
7.7
12
8
H52.2
ICD-10 Finland
Astigmatism
3.1
7.6
39
126
S01AX11
ATC
[U] ofloxacin; ophthalmic
1.7
7.6
167
1028
CHB15
NOMESCO Finland
Puncture of anterior chamber of eye with replacement of aqueous
11.8
7.6
13
11
CKD40
NOMESCO Finland
Endophotocoagulation of retina
2.8
7.5
45
162
CA1AE
NOMESCO Finland
Eye and orbita ultrasound examination
4.8
7.4
23
48
H10.5
ICD-10 Finland
Blepharoconjunctivitis
2.7
7.4
48
180
R4110
NOMESCO Finland
Physiotherapy
0.8
7.4
585
7209
CHB50
NOMESCO Finland
Trabeculotomy
+∞
7.3
7
*
3719
FHL
Other measure in this category
+∞
7.3
7
*
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
1.3
7.3
792
6543
H01.80
ICD-10 Finland
Prolonged inflammation in the edge of the eyelid
3.6
7.2
30
83
H13
ICPC
Plugged feeling ear
1.3
7.2
651
5255
CKC10
NOMESCO Finland
Local photocoagulation of retina
2.0
7.1
80
396
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
2.2
6.9
66
302
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.9
1311
11502
R5210
NOMESCO Finland
Assessment of the improvements needed in the living environment
3.7
6.8
28
77
CDC00
NOMESCO Finland
Enucleation of eye
16.7
6.7
10
6
P20
ICPC
Memory disturbance
1.3
6.7
612
4944
N40
ICD-10 Finland
Hyperplasia of prostate
1.2
6.7
793
6611
H10.0
ICD-10 Finland
Mucopurulent conjunctivitis
1.7
6.7
139
846
CGG99
NOMESCO Finland
Other reconstructive operations on cornea and sclera
22.5
6.7
9
*
N06AX11
ATC
mirtazapine; oral
1.2
6.6
981
8382
3661A
ICD-9 Finland
Cataract, Senile cataract
1.9
6.6
93
498
H52.0
ICD-10 Finland
Hypermetropia
2.6
6.6
44
170
CJG40
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial scleral fixed lens in posterior chamber and iridectomy or iridotomy
14.3
6.4
10
7
Z01.2
ICD-10 Finland
Dental examination
1.2
6.4
942
8044
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
6.3
763
6371
CG2Z4
NOMESCO Finland
Specialised imaging of cornea
8.1
6.3
13
16
H44.4
ICD-10 Finland
Hypotony of eye
18.0
6.3
9
5
H26.02
ICD-10 Finland
Presenil cataract
2.1
6.3
67
326
3711
FHL
Cyclodiateria or cryocoagulation
+∞
6.2
6
*
3656F
ICD-9 Finland
Glaucoma associated with other ocular disorders[GLAUCOMA POST UVEITIDEM]
+∞
6.2
6
*
37511
ICD-8 Finland
Glaucoma, Chronicum irritativum sive congestivum
+∞
6.2
6
*
SPAT1097
SPAT
Recording of ECG
1.3
6.2
542
4351
A44
ICPC
General and Unspecified, Preventive immunization/medic
1.5
6.2
217
1495
F28
ICPC
Limited function/disability (F)
3.2
6.2
30
95
G04CA01
ATC
alfuzosin; oral
1.4
6.2
361
2734
R53
ICD-10 Finland
Malaise and fatigue
1.2
6.1
762
6391
H54.5
ICD-10 Finland
Severe visual impairment, monocular
4.4
6.0
20
46
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
3830
34183
1.88
44.94
26.5
27.4
129.9
130.0
g/l
0.19
3748
33321
3829
34175
1.88
44.87
26.3
27.2
4.3
4.3
e12/l
2.56
3681
32721
3828
34173
1.88
44.69
26.3
27.2
238.2
241.0
e9/l
1.75
3704
32877
3829
34185
1.88
44.69
26.3
27.3
6.8
7.0
e9/l
5.35
3682
32724
3782
33723
1.83
43.12
21.6
22.4
139.5
139.5
mmol/l
0.08
3676
32646
3785
33769
1.83
42.91
21.8
22.6
4.0
4.0
mmol/l
0.04
3671
32635
3713
33148
1.74
39.28
11.0
11.3
22.5
23.3
u/l
1.57
3527
31386
3608
32044
1.68
37.92
17.5
18.6
26.0
27.5
mg/l
1.62
2988
26648
3478
30788
1.60
34.99
5.5
5.4
2.5
2.5
mmol/l
0.05
3079
27203
3328
29193
1.56
34.51
5.3
5.0
2.1
2.1
mu/l
0.16
2921
25759
3376
29716
1.57
34.41
4.8
4.7
4.4
4.4
mmol/l
0.00
2987
26331
3474
30848
1.58
33.37
5.3
5.2
6.1
6.1
mmol/l
0.42
3037
26921
3335
29377
1.55
32.85
4.8
4.7
1.5
1.5
mmol/l
2.00
2923
25817
3349
29704
1.52
30.23
6.8
6.7
41.2
41.3
mmol/mol
0.17
2968
26527
3210
28392
1.47
27.84
4.3
4.2
1.2
1.3
mmol/l
5.88
2785
24635
2854
24730
1.43
27.32
4.3
4.3
14.8
15.8
mm/h
2.55
2569
22335
1627
12794
1.43
26.85
4.9
5.0
—
—
—
0
0
3022
26787
1.40
23.06
6.8
7.4
82.0
82.6
u/l
0.17
2805
24779
2027
16863
1.37
22.77
4.6
4.5
0.0
0.0
estimate
0.00
393
3034
2759
24201
1.37
21.66
4.3
4.1
15.2
15.2
pmol/l
0.27
2396
21213
2039
17115
1.35
21.00
4.7
4.6
0.0
0.0
estimate
1.08
391
2985
2011
16879
1.35
20.56
6.0
6.1
0.0
0.0
estimate
0.00
394
2999
3249
29379
1.40
20.41
17.1
17.9
68.9
68.8
ml/min/173m2
0.10
2662
24284
2783
24572
1.36
20.15
5.7
5.7
2286.6
3010.6
e6/l
0.14
41
438
2791
24678
1.35
19.87
21.0
22.7
14.0
14.0
%
1.18
2717
23981
1866
15656
1.33
18.41
4.5
4.4
79.1
97.0
ng/l
0.17
1460
12305
1176
9259
1.37
17.51
5.1
5.0
0.0
0.0
estimate
0.69
387
2867
1342
10823
1.34
16.98
2.3
2.3
3.2
3.2
mg/l
0.30
1128
9066
2988
26974
1.33
16.80
19.2
20.4
36.9
37.4
%
1.16
1560
15639
1308
10552
1.34
16.40
6.0
5.7
4.0
5.3
ug/l
0.75
1143
9242
992
7724
1.37
15.55
5.2
5.1
1.0
1.0
kg/l
0.21
192
1291
1986
17084
1.29
15.33
2.2
2.2
95.3
93.1
pmol/l
1.17
986
8547
2443
21704
1.28
14.14
4.5
4.6
6.9
6.9
mmol/l
0.50
2280
20374
1106
8916
1.32
13.44
1.8
1.7
26016690.6
13276039.2
pmol/l
0.38
861
7043
1917
16707
1.26
12.33
12.1
11.4
1.5
1.4
inr
0.36
561
4277
653
4928
1.38
12.15
9.0
9.0
—
—
—
0
0
1044
8502
1.30
11.49
5.4
4.9
22.3
22.3
%
0.03
561
4611
1951
17138
1.25
11.39
4.1
4.4
34.4
34.2
g/l
0.49
1779
15573
1586
13614
1.26
11.34
2.7
2.9
136.4
150.1
ug/l
1.45
1402
12122
1224
10256
1.27
10.60
1.6
1.6
20.6
20.2
nmol/l
0.35
1022
8576
1889
16646
1.23
10.37
5.1
5.4
1.7
1.8
e9/l
1.27
1630
14169
2149
19215
1.23
10.21
7.4
8.2
4.2
4.4
e9/l
2.07
1870
16442
2228
20026
1.23
9.96
6.0
6.4
1.2
1.2
mmol/l
0.21
1825
16639
1321
11251
1.25
9.78
2.5
2.5
60.7
59.0
u/l
0.48
1216
10206
1139
9572
1.26
9.42
1.9
1.8
1195.8
1158.7
nmol/l
0.67
839
6951
375
2699
1.43
9.13
5.2
6.1
24.4
24.6
mmol/l
0.41
350
2526
1671
14697
1.22
8.92
2.3
2.2
80.4
80.7
nmol/l
0.16
1449
12516
1551
13561
1.22
8.73
3.1
3.2
2.3
2.4
mmol/l
4.64
1314
11291
1989
17852
1.21
8.48
2.9
3.1
49.2
56.1
u/l
2.66
1768
15872
1583
14022
1.20
7.48
2.2
2.2
—
—
—
0
0
2081
18898
1.19
7.43
5.3
5.8
12.5
12.3
umol/l
0.22
1947
17772
254
1773
1.46
7.32
4.6
4.4
0.9
0.9
%
0.93
237
1671
1365
11957
1.20
7.21
2.1
2.1
186.0
211.8
u/l
0.62
1260
11033
254
1798
1.44
6.82
4.6
4.4
1.6
1.6
%
0.29
238
1693
1722
15478
1.18
6.69
5.2
5.5
59.4
59.3
%
0.16
1567
14158
1985
18069
1.18
6.60
5.2
5.7
1.2
1.2
mmol/l
1.18
1750
16029
1578
14096
1.19
6.56
3.1
3.3
1947.9
2069.5
ng/l
0.41
1341
12243
1338
11790
1.19
6.49
3.9
3.8
8.9
9.4
mg/mmol
0.09
863
7229
139
876
1.61
6.47
5.4
6.0
105.0
104.9
mmol/l
0.02
125
785
1743
15753
1.18
6.20
5.4
5.8
25.2
25.3
%
0.21
1588
14311
427
3350
1.30
6.01
3.3
3.6
1.2
1.2
mmol/l
1.80
369
2856
1707
15430
1.17
6.01
5.2
5.6
2.9
2.8
%
1.84
1554
14099
1257
11123
1.18
5.66
3.2
3.1
381.9
334.2
mg/l
0.14
811
6897
499
4067
1.26
5.18
3.4
3.9
—
—
—
0
0
46
223
2.07
5.12
1.1
1.2
—
—
—
0
0
1258
11212
1.17
5.10
3.3
3.0
6.6
6.6
mmol/l
0.10
1048
9081
1549
14071
1.15
4.83
10.4
10.4
0.0
0.0
e9/l
0.09
1311
11261
47
238
1.98
4.68
1.9
1.8
189.3
204.9
pmol/l
0.38
41
221
398
3214
1.26
4.49
1.6
1.6
—
—
—
0
0
897
7873
1.17
4.32
1.6
1.6
1.2
1.3
mmol/l
1.23
718
6478
664
5705
1.19
4.10
1.2
1.2
0.7
1.5
u/ml
6.43
174
1355
20
74
2.71
4.08
1.2
1.1
—
—
—
0
0
165
1193
1.40
4.07
1.8
1.7
40.2
38.7
u/l
0.44
135
1006
363
2951
1.25
3.89
2.2
1.8
131.2
163.1
ug/g
0.96
279
2230
1721
16024
1.12
3.34
3.9
4.3
—
—
—
0
0
63
395
1.60
3.18
1.5
1.4
—
—
—
0
0
151
1133
1.34
3.05
3.9
3.5
1.5
1.7
mmol/l
1.90
144
1114
25
121
2.07
2.92
1.0
1.1
—
—
—
0
0
451
3863
1.19
2.91
5.0
6.4
120.7
118.5
g/l
1.72
432
3727
672
5952
1.15
2.84
3.5
3.3
0.8
0.9
ug/l
1.63
503
4333
170
1316
1.30
2.79
3.1
3.7
3.8
3.9
mmol/l
0.88
157
1214
322
2686
1.21
2.78
2.5
2.9
56.3
57.5
ml/min/173m2
0.25
132
1268
1041
9518
1.12
2.68
3.2
3.0
37.8
35.4
u/l
0.22
961
8906
168
1308
1.30
2.66
1.2
1.2
222.4
207.2
u/ml
0.06
155
1176
143
1089
1.32
2.65
4.1
3.5
7.7
7.9
mmol/l
0.18
137
1070
907
8240
1.13
2.60
3.0
3.1
2.5
2.5
mmol/l
5.91
801
7049
721
6458
1.14
2.59
2.2
2.4
11.3
11.6
umol/l
0.42
653
5845
311
2608
1.21
2.56
1.4
1.5
—
—
—
0
0
152
1177
1.30
2.52
1.1
1.1
—
—
—
0
0
9
26
3.47
2.48
1.0
1.0
—
—
—
0
0
18
83
2.17
2.40
1.0
1.1
—
—
—
0
0
101
746
1.36
2.33
1.9
1.7
10.2
12.9
mg/l
1.92
93
677
467
4095
1.16
2.29
2.4
2.5
4.4
6.3
ug/l
5.31
375
3358
173
2149
0.80
2.27
5.8
7.2
24.5
24.4
mmol/l
0.23
157
1969
104
777
1.35
2.25
1.7
1.6
—
—
—
0
0
543
4820
1.14
2.24
4.6
5.8
1.3
1.2
mmol/l
0.30
395
3709
5
9
5.56
2.21
1.0
1.0
—
—
—
0
0
30
173
1.74
2.16
1.1
1.1
—
—
—
0
0
792
7217
1.12
2.15
1.5
1.7
1.7
1.6
mg/l
0.23
632
5629
20
101
1.98
2.15
1.0
1.2
—
—
—
0
0
20
101
1.98
2.15
1.9
1.5
0.2
0.2
nmol/l
0.14
12
79
801
7315
1.12
2.09
1.9
1.9
—
—
—
0
0
78
567
1.38
2.03
1.5
1.6
—
—
—
0
0
67
475
1.42
2.01
1.5
1.4
—
—
—
0
0
320
2757
1.17
2.00
1.3
1.3
—
—
—
0
0
980
9066
1.10
2.00
2.6
2.8
6390.9
7898.0
umol/l
0.39
813
7480
181
1480
1.23
1.98
2.6
2.0
11.2
11.1
nmol/l
0.03
157
1241
256
2172
1.19
1.92
3.0
2.9
0.3
0.4
e6/l
0.40
249
2131
16
78
2.05
1.90
1.6
1.4
80.9
123.2
ng/l
1.85
16
78
199
1653
1.21
1.88
2.9
3.0
4.4
4.3
pmol/l
0.74
174
1388
25
143
1.75
1.88
1.8
1.8
0.2
0.2
e9/l
0.37
25
127
17
86
1.98
1.84
1.2
1.1
1.0
1.1
ratio
—
6
24
39
253
1.55
1.83
1.2
1.2
65.4
218.8
miu/ml
—
8
55
1426
13469
1.09
1.83
4.0
4.1
131.7
140.1
e6/l
0.09
1081
9796
130
1049
1.25
1.65
1.5
1.4
238.3
273.4
ug/g
1.57
90
640
7
25
2.80
1.65
1.1
1.5
—
—
—
0
0
205
1734
1.19
1.64
1.8
1.8
—
—
—
0
0
910
8468
1.09
1.64
2.7
2.8
6.2
5.4
e6/l
0.84
797
7406
23
135
1.71
1.62
1.2
1.2
—
—
—
0
0
71
532
1.34
1.59
2.1
2.0
32.0
32.5
pg
0.34
71
526
532
4826
1.12
1.59
4.7
5.8
11.7
11.8
kpa
0.13
503
4542
82
1061
0.77
1.59
1.4
1.3
—
—
—
0
0
82
1061
0.77
1.59
1.4
1.3
—
—
—
0
0
532
4827
1.12
1.59
4.7
5.8
5.1
5.1
kpa
0.11
502
4549
25
152
1.65
1.56
1.8
1.8
464.5
501.5
e6/l
0.13
25
129
220
1884
1.18
1.54
1.8
2.0
—
—
—
0
0
502
4549
1.12
1.54
5.0
4.8
34.0
34.0
%
0.01
320
2823
58
784
0.74
1.54
1.5
1.6
—
—
—
0
0
52
714
0.72
1.53
1.8
2.3
201.5
211.6
%
0.34
46
672
286
3258
0.87
1.52
2.4
2.3
42.2
36.4
u/l
0.32
239
2748
71
929
0.76
1.51
1.3
1.6
13075.2
17618.7
e6/l
0.56
50
649
75
574
1.31
1.48
2.3
2.2
37.4
26.0
mg/l
0.52
17
137
506
4601
1.11
1.47
1.3
1.3
35.0
40.6
iu/ml
0.36
166
1408
649
5988
1.10
1.41
2.1
2.4
2.3
2.3
g/l
0.22
590
5427
103
829
1.25
1.39
1.4
1.3
—
—
—
0
0
184
1569
1.18
1.38
1.3
1.3
65.2
57.4
au/ml
—
5
67
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
137
1642
0.83
1.38
2.2
2.6
0.4
0.4
u/ml
0.54
76
950
166
1954
0.84
1.37
2.7
3.3
23.6
24.2
mmol/l
1.81
150
1740
6
23
2.61
1.36
1.3
1.0
—
—
—
0
0
324
3619
0.89
1.31
4.2
5.3
1.4
1.4
mmol/l
0.32
306
3465
8
34
2.35
1.29
1.6
1.4
—
—
—
0
0
53
396
1.34
1.27
1.7
1.7
22.0
25.2
u/ml
0.16
13
93
259
2290
1.14
1.23
3.8
3.2
24.9
25.2
mmol/l
0.53
252
2233
162
1386
1.18
1.21
3.0
2.7
—
—
—
0
0
42
306
1.38
1.19
2.3
1.3
15.9
12.5
u/l
0.56
35
243
1248
11912
1.07
1.15
3.5
3.5
130.4
89.3
e6/l
0.36
1018
9237
26
174
1.50
1.15
1.0
1.1
0.2
13.7
nmol/l
—
8
49
41
553
0.74
1.14
1.1
1.2
—
—
—
0
0
297
2665
1.12
1.14
3.4
3.0
126.2
125.9
g/l
0.08
285
2604
13
222
0.58
1.13
1.6
1.4
—
—
—
0
0
13
222
0.58
1.13
1.6
1.4
—
—
—
0
0
67
528
1.27
1.12
2.8
4.1
263.2
3670.0
iu/ml
—
9
74
211
1856
1.14
1.11
1.8
1.8
1.4
2.3
ug/l
0.99
171
1564
28
399
0.70
1.09
2.1
2.0
214.3
794.7
u/ml
0.41
28
388
41
547
0.75
1.07
1.1
1.3
—
—
—
0
0
315
2851
1.11
1.05
1.9
2.0
380.7
382.5
nmol/l
0.04
272
2535
24
162
1.48
1.03
1.1
1.2
—
—
—
0
0
1136
10853
1.06
1.01
3.3
3.5
0.4
0.6
e6/l
1.02
910
8308
14
83
1.69
1.01
1.5
1.7
1.2
1.2
mmol/l
0.05
14
78
604
5648
1.08
1.01
2.2
2.5
20.2
20.6
%
0.26
488
4710
116
984
1.18
1.00
2.1
2.2
125.1
125.6
g/l
0.08
95
709
646
6062
1.08
0.98
1.6
1.9
29.9
30.1
s
0.26
616
5847
13
76
1.71
0.98
1.8
1.6
33.2
28.3
%
0.51
13
66
25
355
0.70
0.98
1.3
1.5
—
—
—
0
0
67
540
1.24
0.97
1.2
1.4
—
—
—
0
0
19
124
1.53
0.96
1.4
1.7
14.0
2146.4
u/l
—
5
43
18
116
1.55
0.96
1.4
1.4
19.5
23.1
%
0.33
13
98
465
4312
1.09
0.96
3.7
3.1
250.4
261.5
ng/l
0.17
428
3941
855
8121
1.07
0.92
4.3
4.3
299.5
435.7
ng/l
0.49
746
7154
9
52
1.73
0.92
1.1
1.2
—
—
—
0
0
18
118
1.53
0.90
2.6
3.0
26.3
29.8
umol/l
—
9
88
12
195
0.61
0.90
1.2
1.1
—
—
—
0
0
5
101
0.49
0.89
1.0
1.0
—
—
—
0
0
12
71
1.69
0.88
1.8
2.0
—
—
—
0
0
25
177
1.41
0.88
1.4
1.6
57.6
67.5
%
0.84
16
143
8
43
1.86
0.87
1.6
1.4
51.0
49.3
umol/l
—
8
43
95
805
1.18
0.86
2.2
2.4
1.9
1.8
mg/l
0.72
83
696
23
161
1.43
0.86
1.1
1.2
—
—
—
0
0
21
299
0.70
0.86
1.7
1.2
4.8
4.8
u/ml
—
5
148
17
112
1.52
0.84
1.4
1.2
—
—
—
0
0
8
45
1.78
0.84
1.5
1.1
—
—
—
0
0
72
597
1.21
0.83
1.2
1.4
—
—
—
0
0
65
534
1.22
0.82
5.6
8.0
7.3
7.5
mmol/l
0.22
54
432
39
302
1.29
0.81
1.0
1.1
—
19.1
—
0
7
28
375
0.74
0.81
1.2
1.1
—
—
—
0
0
565
5322
1.07
0.80
2.2
2.3
1.8
1.8
%
0.08
486
4587
11
176
0.62
0.79
1.4
1.1
—
—
—
0
0
25
181
1.38
0.79
1.8
1.8
15.8
16.3
%
0.06
13
64
(46236287) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Pleural fluid by Immunoassay
0
24
0.00
0.79
0.0
1.3
—
3634.2
—
0
16
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
0
25
0.00
0.79
0.0
1.5
—
—
—
0
0
0
26
0.00
0.78
0.0
1.7
—
—
—
0
0
13
82
1.59
0.78
1.4
1.7
1.2
1.2
mmol/l
0.29
13
77
7
124
0.56
0.77
2.6
2.0
9.9
61.3
u/l
—
7
116
109
945
1.16
0.77
1.8
2.3
65.5
73.2
ug/min
0.13
58
527
5
100
0.50
0.77
1.0
2.8
—
—
—
0
0
0
28
0.00
0.76
0.0
1.3
—
—
—
0
0
26
348
0.75
0.76
1.2
1.1
307.8
314.1
u/ml
0.05
17
199
25
336
0.74
0.75
1.3
1.5
—
—
—
0
0
5
24
2.08
0.74
1.4
1.3
—
—
—
0
0
60
496
1.21
0.73
1.2
1.4
—
—
—
0
0
64
765
0.83
0.73
1.7
2.0
87.4
88.2
%
0.12
54
728
9
55
1.64
0.73
2.3
2.2
—
—
—
0
0
9
56
1.61
0.72
2.3
2.2
—
—
—
0
0
22
159
1.39
0.72
1.8
2.0
650.5
563.5
e6/l
0.24
12
68
58
480
1.21
0.71
1.2
1.4
—
—
—
0
0
93
806
1.16
0.68
1.4
1.7
—
—
—
0
0
17
239
0.71
0.68
1.5
1.3
—
—
—
0
0
17
239
0.71
0.68
1.5
1.3
—
—
—
0
0
54
446
1.21
0.68
1.4
1.4
63.5
63.0
%
0.04
34
283
14
204
0.69
0.68
1.0
1.0
—
—
—
0
0
9
59
1.53
0.68
1.0
1.2
—
—
—
0
0
49
401
1.22
0.67
3.0
4.0
71.6
46.3
u/ml
0.28
49
391
80
686
1.17
0.67
1.2
1.2
26.3
4.1
u/ml
0.48
13
75
15
102
1.47
0.67
1.1
1.3
33.4
32.0
%
—
8
69
14
94
1.49
0.66
1.1
1.2
—
—
—
0
0
102
893
1.15
0.66
2.5
2.5
16.3
15.6
%
1.13
60
464
5
28
1.79
0.66
1.0
1.0
—
—
—
0
0
19
137
1.39
0.64
1.7
2.3
—
—
—
0
0
19
137
1.39
0.64
1.7
2.3
—
—
—
0
0
395
3712
1.07
0.63
2.5
2.4
66.2
65.8
g/l
0.52
342
3243
5
30
1.67
0.61
1.0
1.1
—
—
—
0
0
360
3378
1.07
0.61
3.1
3.3
93.4
95.5
ng/l
0.13
297
2762
8
50
1.60
0.61
1.5
1.1
—
—
—
0
0
62
527
1.18
0.60
1.3
1.4
—
—
—
0
0
0
21
0.00
0.60
0.0
1.1
—
—
—
0
0
479
4542
1.06
0.59
3.7
3.7
34.1
26.8
ug/l
0.13
408
3740
80
695
1.15
0.59
1.2
1.2
3.8
5.5
u/ml
0.51
17
119
689
6600
1.05
0.59
30.7
31.7
1.5
1.5
inr
0.35
101
885
0
22
0.00
0.59
0.0
1.1
—
5.3
—
0
7
0
22
0.00
0.59
0.0
1.1
—
2.2
—
0
11
45
541
0.83
0.58
1.4
1.6
1.8
3.7
mg/l
1.23
32
433
38
464
0.82
0.58
3.4
3.5
—
—
—
0
0
7
113
0.62
0.58
2.0
1.1
—
—
—
0
0
23
176
1.31
0.56
1.9
1.8
—
—
—
0
0
48
402
1.20
0.56
4.0
3.8
331.6
340.6
umol/l
0.16
41
331
71
616
1.15
0.55
3.6
3.3
56.3
59.8
%
1.07
71
616
24
307
0.78
0.55
1.6
1.2
4.0
4.1
u/ml
—
6
94
18
133
1.35
0.54
1.3
1.5
22.4
18.5
%
0.24
13
121
532
5077
1.05
0.54
1.9
1.8
—
—
—
0
0
15
205
0.73
0.54
1.7
2.2
93.4
61.3
ug/min
—
5
50
154
1405
1.10
0.53
1.1
1.2
134.0
122.5
iu/ml
0.12
50
468
32
258
1.24
0.53
1.2
1.4
—
—
—
0
0
45
534
0.84
0.52
1.3
1.4
—
—
—
0
0
20
260
0.77
0.52
1.4
1.5
—
—
—
0
0
529
5054
1.05
0.52
1.9
1.8
—
—
—
0
0
41
341
1.20
0.52
1.4
1.5
—
—
—
0
0
107
1191
0.90
0.52
2.6
2.3
0.0
0.0
g/l
0.00
99
1073
9
65
1.39
0.50
1.2
2.4
217.4
210.2
%
—
9
58
372
3923
0.94
0.50
2.4
2.5
10.5
10.2
umol/l
0.07
315
3380
125
1135
1.10
0.49
1.7
1.6
184.0
241.5
titre
—
5
54
73
642
1.14
0.49
1.4
1.7
2.2
4.2
iu/l
4.85
16
184
79
890
0.89
0.48
1.4
1.5
—
—
—
0
0
7
46
1.52
0.48
1.1
1.6
—
—
—
0
0
7
48
1.46
0.46
1.1
1.3
—
—
—
0
0
20
155
1.29
0.46
1.3
1.5
5.1
3.1
%
0.36
13
127
113
1025
1.10
0.46
1.2
1.2
0.7
0.9
u/ml
0.08
13
99
67
589
1.14
0.46
1.2
1.2
2.2
7.9
u/ml
—
6
48
5
85
0.59
0.45
1.0
1.1
—
—
—
0
0
206
2205
0.93
0.45
1.8
1.6
1.5
1.5
g/l
0.20
175
1854
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
12
163
0.74
0.43
1.1
1.1
—
—
—
0
0
9
128
0.70
0.43
1.3
1.1
—
—
—
0
0
9
129
0.70
0.43
1.2
1.4
—
—
—
0
0
61
537
1.14
0.42
1.1
1.1
—
—
—
0
0
160
1484
1.08
0.42
2.9
2.9
16707.4
2015.8
u/ml
0.44
138
1234
111
1214
0.91
0.41
2.6
2.3
0.0
0.0
g/l
0.00
100
1078
0
15
0.00
0.41
0.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
1.4
—
—
—
0
0
91
1003
0.91
0.40
1.2
1.3
—
—
—
0
0
53
464
1.14
0.40
1.3
1.3
1096.2
307.8
u/l
0.71
47
436
18
141
1.28
0.40
1.1
1.2
14.9
14.0
umol/l
—
8
89
537
5177
1.04
0.39
4.2
4.8
1.1
1.0
mmol/l
0.72
487
4680
5
35
1.43
0.39
1.4
1.1
—
—
—
0
0
66
588
1.12
0.39
1.2
1.3
—
—
—
0
0
9
66
1.36
0.38
1.0
1.0
—
—
—
0
0
157
1463
1.08
0.38
1.8
2.1
1682.6
562.1
ug/l
0.42
145
1374
87
790
1.10
0.37
1.5
1.5
55.8
5.0
iu/ml
0.44
20
200
5
37
1.35
0.37
1.0
1.2
—
—
—
0
0
132
1422
0.93
0.37
3.5
3.3
0.8
0.8
nmol/l
0.19
101
1078
37
318
1.16
0.36
1.4
1.4
74.0
47.3
titre
—
5
22
6
42
1.43
0.35
12.3
15.9
3.4
5.2
mmol/l
—
6
42
6
43
1.40
0.35
1.2
1.2
—
—
—
0
0
46
404
1.14
0.35
2.0
2.4
3.4
1.9
u/field
0.25
12
123
51
574
0.89
0.34
1.4
1.4
105638.4
57022.5
e6/l
0.38
29
342
39
445
0.88
0.32
3.0
3.8
62.7
58.4
%
0.50
19
276
42
370
1.14
0.31
1.2
1.3
285.3
259.2
pmol/l
0.16
35
274
346
3595
0.96
0.31
5.5
5.8
11.9
11.7
mmol/l
0.19
323
3352
48
428
1.12
0.30
1.4
1.4
—
—
—
0
0
59
650
0.91
0.29
1.4
1.5
—
—
—
0
0
106
987
1.08
0.29
1.2
1.2
—
—
—
0
0
51
459
1.11
0.28
1.1
1.1
—
—
—
0
0
332
3199
1.04
0.28
1.3
1.3
—
—
—
0
0
298
2865
1.04
0.28
1.8
1.8
—
—
—
0
0
632
6163
1.03
0.27
2.4
2.6
0.8
0.8
mmol/l
2.25
569
5595
9
117
0.77
0.27
1.0
1.2
—
68.1
%
—
0
16
95
885
1.07
0.26
1.4
1.4
—
—
—
0
0
142
1501
0.94
0.26
2.3
2.4
1.4
1.1
g/l
0.43
118
1239
353
3412
1.04
0.26
3.3
2.9
4.4
4.4
kpa
0.10
339
3294
24
206
1.17
0.26
1.6
2.0
11.4
2.3
u/field
0.81
17
139
11
86
1.28
0.26
1.0
1.3
—
—
—
0
0
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
11
86
1.28
0.26
1.5
2.3
187.4
187.0
%
0.00
11
77
57
624
0.91
0.26
1.4
1.5
11395.5
1717.5
e6/l
0.46
45
445
337
3486
0.96
0.26
1.8
2.0
0.2
0.2
g/l
0.93
304
3197
113
1061
1.07
0.26
1.5
1.6
—
—
—
0
0
13
160
0.81
0.26
1.1
1.1
—
—
—
0
0
33
293
1.13
0.24
1.2
1.2
7.8
8.1
mmol/l
0.23
24
188
12
147
0.82
0.23
1.3
1.6
—
—
—
0
0
12
147
0.82
0.23
1.3
1.6
—
—
—
0
0
30
338
0.89
0.23
1.5
1.3
—
—
—
0
0
106
999
1.06
0.23
1.2
1.2
—
—
—
0
0
10
125
0.80
0.23
1.9
2.1
42.2
54.6
umol/l
—
5
88
77
824
0.93
0.22
1.9
1.8
—
—
—
0
0
33
295
1.12
0.22
1.2
1.1
—
—
—
0
0
262
2532
1.04
0.21
3.4
3.6
1.5
2.1
mmol/l
1.32
185
1866
26
229
1.14
0.21
1.5
1.5
6.7
7.8
u/l
0.16
13
105
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
0
11
0.00
0.21
0.0
1.9
—
23.9
—
0
11
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
5
43
1.16
0.21
1.0
1.0
—
—
—
0
0
211
2033
1.04
0.20
2.4
2.4
0.7
0.7
%
0.18
201
1954
44
480
0.92
0.20
1.3
1.4
—
—
—
0
0
0
14
0.00
0.20
0.0
2.6
—
—
—
0
0
6
48
1.25
0.20
1.3
1.1
—
—
—
0
0
530
5186
1.02
0.20
4.9
5.7
104.4
104.2
mmol/l
0.60
513
5049
30
334
0.90
0.20
1.5
1.3
—
—
—
0
0
53
490
1.08
0.19
1.2
1.1
—
—
—
0
0
76
809
0.94
0.19
1.3
1.2
—
—
—
0
0
185
1782
1.04
0.19
2.2
2.3
—
—
—
0
0
170
1636
1.04
0.18
2.3
2.4
2.9
3.2
g/l
2.46
124
1241
175
1686
1.04
0.18
2.2
2.3
10.1
10.3
g/l
0.21
136
1368
449
4393
1.02
0.18
1.3
1.2
19.4
15.5
u/ml
0.36
161
1448
12
100
1.20
0.18
1.1
1.2
—
—
—
0
0
185
1786
1.04
0.17
2.2
2.3
7.1
7.6
g/l
2.77
127
1265
22
247
0.89
0.17
1.2
1.7
—
—
—
0
0
118
1129
1.05
0.17
2.4
3.1
24.7
25.2
mmol/l
0.47
110
968
134
1395
0.96
0.17
2.4
2.2
37.6
36.9
g/l
0.75
107
1132
21
186
1.13
0.16
1.3
1.1
14.4
34.2
u/l
2.03
13
136
21
186
1.13
0.16
1.3
1.1
76.6
90.3
u/l
0.62
15
139
71
670
1.06
0.16
2.1
1.9
1.6
1.7
mmol/l
0.78
71
652
184
1779
1.04
0.16
2.2
2.3
3.9
3.7
g/l
0.34
121
1215
8
71
1.13
0.16
1.4
1.5
8.1
9.5
ug/l
—
8
71
8
72
1.11
0.16
4.3
7.4
14.0
13.7
%
—
8
72
17
193
0.88
0.15
1.2
1.3
—
—
—
0
0
6
79
0.76
0.15
1.0
1.1
—
—
—
0
0
6
79
0.76
0.15
1.3
1.1
—
—
—
0
0
6
80
0.75
0.15
1.0
1.1
—
—
—
0
0
14
161
0.87
0.15
1.1
1.1
—
—
—
0
0
19
213
0.89
0.15
1.2
1.2
43.6
23.9
u/l
0.65
14
173
13
150
0.87
0.14
1.3
1.6
—
—
—
0
0
7
89
0.79
0.14
1.3
1.1
—
—
—
0
0
95
909
1.05
0.14
3.5
4.4
5.0
5.0
kpa
0.06
95
883
420
4124
1.02
0.14
3.4
3.3
5.8
5.8
kpa
0.58
405
3997
95
911
1.04
0.13
3.6
4.0
37.1
29.6
mg/l
0.92
66
593
17
151
1.13
0.13
1.8
1.3
—
—
—
0
0
49
520
0.94
0.13
5.0
5.9
12.5
12.8
mg/l
0.14
43
466
19
211
0.90
0.13
2.1
3.2
—
—
—
0
0
13
113
1.15
0.13
1.0
1.1
—
—
—
0
0
9
110
0.82
0.13
1.1
1.2
—
—
—
0
0
44
413
1.07
0.12
3.4
3.1
—
—
—
0
0
68
649
1.05
0.12
1.2
1.2
32.7
49.1
u/l
0.97
61
560
125
1290
0.97
0.12
2.4
2.3
0.0
0.0
g/l
0.42
112
1149
22
201
1.09
0.11
2.0
2.0
—
—
—
0
0
18
163
1.10
0.10
1.5
1.4
2.6
2.9
%
—
5
37
38
358
1.06
0.10
1.1
1.3
24837.1
169545.5
e6/l
2.61
16
237
34
319
1.07
0.10
1.9
2.2
748.0
637.4
ml
0.25
21
191
20
183
1.09
0.10
1.6
1.5
—
—
—
0
0
25
269
0.93
0.10
2.7
2.4
—
—
—
0
0
13
116
1.12
0.09
1.8
1.7
1.7
10.2
nmol/l
—
8
92
25
268
0.93
0.09
1.2
1.1
—
—
—
0
0
417
4117
1.01
0.09
3.4
3.3
1.7
2.0
mmol/l
0.93
322
3316
30
319
0.94
0.09
1.3
1.5
—
—
—
0
0
30
319
0.94
0.09
1.3
1.5
—
—
—
0
0
30
319
0.94
0.09
1.3
1.5
—
—
—
0
0
270
2656
1.02
0.09
3.4
3.7
5.2
5.2
kpa
0.09
249
2396
22
237
0.93
0.09
1.0
1.0
376.7
311.5
ng/l
0.40
11
147
479
4843
0.99
0.08
3.2
3.7
249.5
249.2
u/l
0.02
441
4487
156
1527
1.02
0.08
3.0
2.8
32.0
62.7
mg/l
2.47
131
1265
(3011547) Coagulation factor VII activity actual/normal in Platelet poor plasma by Coagulation assay
5
63
0.79
0.08
1.0
1.1
116.8
95.1
%
—
5
54
152
1488
1.02
0.08
3.0
2.8
2.1
3.3
ratio
0.43
11
110
11
123
0.89
0.08
1.3
1.0
—
—
—
0
0
6
75
0.80
0.07
1.2
1.1
—
—
—
0
0
67
692
0.97
0.07
3.1
3.9
1.5
1.5
%
0.07
49
517
189
1922
0.98
0.07
1.5
1.5
1.5
1.6
%
1.98
157
1571
80
823
0.97
0.07
2.5
2.9
193.0
879.0
u/ml
1.19
74
743
7
85
0.82
0.07
1.3
1.1
—
—
—
0
0
17
157
1.08
0.07
1.1
1.5
4.7
7.1
u/l
1.13
11
128
9
103
0.87
0.06
1.3
1.9
17.2
384.7
ug/l
—
9
96
24
227
1.06
0.05
3.7
3.8
—
—
—
0
0
37
356
1.04
0.05
1.0
1.1
15.2
82.9
iu/ml
—
6
63
21
222
0.95
0.05
1.1
1.2
114.3
86.0
u/l
0.33
16
187
56
575
0.97
0.04
1.5
1.3
713.7
684.1
e6/l
0.03
50
477
56
574
0.98
0.04
1.5
1.3
17.6
27.5
e6/l
0.23
48
451
44
427
1.03
0.04
1.3
1.2
—
21.1
—
0
6
149
1508
0.99
0.04
1.3
1.2
—
—
—
0
0
156
1578
0.99
0.04
4.2
4.1
24.3
24.9
mmol/l
1.41
141
1391
670
6727
1.00
0.03
3.0
3.0
1.2
1.4
e6/l
0.41
432
3866
111
1125
0.99
0.03
1.4
1.6
—
—
—
0
0
10
92
1.09
0.03
1.9
2.0
—
—
—
0
0
49
501
0.98
0.03
1.3
1.4
—
—
—
0
0
14
132
1.06
0.02
1.1
1.0
—
—
—
0
0
49
500
0.98
0.02
1.3
1.4
—
—
—
0
0
29
281
1.03
0.02
1.0
1.1
—
—
—
0
0
37
379
0.98
0.02
1.2
1.2
41.0
60.1
u/l
3.68
26
249
23
238
0.97
0.02
1.0
1.0
798.2
649.7
ng/l
0.58
11
143
884
8854
1.00
0.01
2.2
2.5
—
—
—
0
0
50
492
1.02
0.01
1.3
1.4
—
—
—
0
0
51
502
1.02
0.01
1.3
1.4
—
—
—
0
0
20
193
1.04
0.01
1.4
1.5
—
—
—
0
0
20
193
1.04
0.01
1.4
1.5
—
—
—
0
0
20
193
1.04
0.01
1.4
1.5
—
—
—
0
0
20
193
1.04
0.01
1.4
1.5
—
—
—
0
0
23
237
0.97
0.01
1.0
1.0
39.1
43.6
ng/l
0.34
12
146
23
223
1.03
0.01
1.3
1.4
—
—
—
0
0
25
257
0.97
0.01
1.2
1.1
122.9
116.7
%
0.49
18
225
36
367
0.98
0.01
1.1
1.2
126.8
113.9
u/ml
0.53
12
69
631
6320
1.00
0.01
3.2
3.2
2.5
2.9
e6/l
0.57
398
3500
154
1532
1.01
0.01
3.0
2.8
45.2
95.8
mg/l
0.78
128
1269
70
693
1.01
0.01
1.5
2.0
31.6
31.9
umol/l
0.02
53
555
28
286
0.98
0.00
1.5
1.3
—
—
—
0
0
23
224
1.03
0.00
1.3
1.4
—
—
—
0
0
33
336
0.98
0.00
1.1
1.1
—
—
—
0
0
54
546
0.99
0.00
2.2
1.9
89.9
89.0
%
0.73
54
539
215
2143
1.00
0.00
2.2
2.7
10.3
10.6
g/l
0.53
194
1928
117
1164
1.01
0.00
1.2
1.2
—
—
—
0
0
31
311
1.00
0.00
1.6
1.4
—
—
—
0
0
33
325
1.02
0.00
1.1
1.2
—
—
—
0
0
50
496
1.01
0.00
1.3
1.4
—
—
—
0
0
53
526
1.01
0.00
1.4
1.4
—
—
—
0
0
32
321
1.00
0.00
1.1
1.3
—
—
—
0
0
14
141
0.99
0.00
1.5
1.5
—
—
—
0
0
23
225
1.02
0.00
1.3
1.2
—
—
—
0
0
18
180
1.00
0.00
1.1
1.1
—
—
—
0
0
18
180
1.00
0.00
1.1
1.1
—
—
—
0
0
18
180
1.00
0.00
1.1
1.1
0.4
1.1
u/ml
—
5
65
18
180
1.00
0.00
1.1
1.1
—
—
—
0
0
163
1628
1.00
0.00
3.4
4.1
63.6
89.6
u/ml
0.41
154
1554
45
447
1.01
0.00
1.4
1.4
5.8
6.6
mmol/l
1.15
40
412
84
837
1.00
0.00
1.4
1.5
—
—
—
0
0
50
502
1.00
0.00
1.3
1.4
—
—
—
0
0
18
179
1.01
0.00
1.1
1.1
—
—
—
0
0
18
179
1.01
0.00
1.1
1.1
—
—
—
0
0
54
539
1.00
0.00
2.4
1.3
0.8
0.8
nmol/l
0.12
49
429
33
332
0.99
0.00
1.5
1.4
29.3
27.4
%
0.10
20
214
17
167
1.02
0.00
1.3
1.2
10.4
11.8
mmol/l
—
7
53
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
1.1
—
0
7
0
5
0.00
0.00
0.0
4.8
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
8.0
—
74.8
—
0
5
5
59
0.85
0.00
1.0
1.2
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
6
61
0.98
0.00
1.2
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
0.00
1.3
1.3
0.4
0.3
g/l
—
6
49
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
2.6
1.5
—
—
—
0
0
6
68
0.88
0.00
1.2
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
7
76
0.92
0.00
1.1
1.1
—
—
—
0
0
8
85
0.94
0.00
1.5
1.2
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint H7_GLAUCOMA_XFG and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCOMA_XFG | 0.876 [0.82, 0.94] | < 0.001 |
| Birth year | 0.994 [0.99, 1.0] | 0.178 |
During the follow-up period (1.1.1998 — 31.12.2019), 9065 out of 22936 females with H7_GLAUCOMA_XFG died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_GLAUCOMA_XFG | 0.91 [0.84, 0.99] | 0.032 |
| Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 4878 out of 11833 males with H7_GLAUCOMA_XFG died.
Mortality risk
Mortality risk for people of age
years, who have H7_GLAUCOMA_XFG.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.071% | 0.185% |
| 5 | 0.498% | 0.955% |
| 10 | 1.294% | 2.41% |
| 15 | 2.583% | 4.733% |
| 20 | 4.311% | 7.942% |
Relationships between endpoints
↥Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation
GWS hits: 20
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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