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Glaucoma, exfoliation

H7_GLAUCOMA_XFG

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

FinnGen phenotype data

429209 individuals

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Apply sex-specific rule None

429209

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Check conditions None

429209

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.10
Hospital discharge: ICD-9 3651B
Hospital discharge: ICD-8 37512
Cause of death: ICD-10 H40.10
Cause of death: ICD-9 3651B
Cause of death: ICD-8 37512

2 out of 7 registries used, show all original rules.

3576

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Check minimum number of events None

3576

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Include endpoints None

3576

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Remove individuals based on genotype QC

3424

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H7_GLAUCOMA_XFG

Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H401
Name in latin Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis

Summary Statistics

Key figures

All Female Male
Number of individuals 3424 1890 1534
Unadjusted prevalence (%) 0.83 0.82 0.84
Mean age at first event (years) 71.20 70.85 71.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 2.37 [1.96, 2.85] 2.1e-19 851
15 years 0.01 1.47 [1.22, 1.76] 3.5e-5 453
5 years 0.00 1.78 [1.47, 2.16] 3.5e-9 229
1 year 0.00 2.23 [1.65, 3.01] 1.9e-7 56

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation
GWS hits: 10

Survival analyses between endpoints

Plot

before Glaucoma, exfoliation
after Glaucoma, exfoliation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Glaucoma, exfoliation

Endpoint not on priority list, no data to show.