Polyhydramnios

O15_POLYHYDR

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O40
  • Hospital discharge: ICD-9 657
  • Hospital discharge: ICD-8 6344
  • Cause of death: ICD-10 O40
  • Cause of death: ICD-9 657
  • Cause of death: ICD-8 6344

2 out of 7 registries used, show all original rules.

1908

4. Check minimum number of events

None

1908

5. Include endpoints

None

1908

6. Filter based on genotype QC (FinnGen only)

1908

Control definitions (FinnGen only)

Control exclude
O15_MATERN_CARE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O30-O48
Name in latin
Hydramnion

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 12633 12633 -
Only index persons 12478 12478 -
Unadjusted period prevalence (%)
Whole population 0.36 0.36 -
Only index persons 0.46 0.46 -
Median age at first event (years)
Whole population - 31.06 -
Only index persons - 31.05 -

-FinnGen-

Key figures

All Female Male
Number of individuals 1908 1908 -
Unadjusted period prevalence (%) 0.65 0.65 -
Median age at first event (years) 31.28 31.28 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1656
Matched controls
16561
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
16.1
323.0
637
617
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1322.6
323.0
474
5
O40
ICD-10 Finland
Polyhydramnios
+∞
323.0
1413
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
+∞
323.0
387
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
17.6
275.5
456
349
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
9.5
224.6
516
754
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
15.1
219.1
384
324
O82.0
ICD-10 Finland
Delivery by elective caesarean section
29.3
212.5
292
120
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
7.8
211.7
561
1019
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
5.7
200.2
744
2087
O32.1
ICD-10 Finland
Maternal care for breech presentation
314.3
194.6
194
7
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
7.6
187.4
499
891
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4.0
153.2
953
4164
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
1541.5
146.1
140
*
MAA00
NOMESCO Finland
Amniocentesis
29.6
145.8
199
76
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
+∞
140.7
133
*
6570A
ICD-9 Finland
Polyhydramnios[POLYHYDRAMNION, RASKAUDEN AIKANA]
+∞
135.3
128
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
4.1
135.1
705
2550
Z39.2
ICD-10 Finland
Routine postpartum follow-up
4.3
132.3
623
2041
SPAT1379
SPAT
Health check-up of pregnant person
4.5
127.0
544
1615
SPAT1197
SPAT
Extensive health check-up of expecting family
4.1
123.9
608
2045
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
184.6
116.0
120
7
SPAT1380
SPAT
Postpartum check-up
4.5
112.4
466
1315
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
18.8
112.0
176
104
O48
ICD-10 Finland
Prolonged pregnancy
1050.8
102.3
99
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.6
101.3
596
2257
SPAT1196
SPAT
Monitoring of normal pregnancy
4.8
96.2
365
924
W84
ICPC
Pregnancy high risk
8.3
96.1
226
309
W78
ICPC
Pregnancy
3.4
96.1
624
2531
63440
ICD-8 Finland
Other complications of pregnancy, Premature rupture of membrane without delivery
+∞
90.4
86
*
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
+∞
84.1
80
*
XMA22
NOMESCO Finland
General examination of pregnant woman
5.0
82.2
290
670
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
82.0
78
*
O80.8
ICD-10 Finland
Other single spontaneous delivery
6.9
79.7
213
349
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.5
76.1
428
1509
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.0
75.8
224
418
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
75.6
72
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
3.3
74.0
459
1736
O99.80
ICD-10 Finland
The fear of childbirth
5.2
72.9
244
528
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
+∞
70.3
67
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.3
69.1
282
748
MAC96
NOMESCO Finland
Other induction or advancement of labour
8.0
66.4
157
213
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
4.9
66.0
237
551
O60
ICD-10 Finland
Preterm labour and delivery
12.0
64.9
122
109
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
61.9
59
*
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
609.5
60.1
59
*
O30.0
ICD-10 Finland
Twin pregnancy
+∞
59.7
57
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
3.0
58.7
418
1699
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
307.8
58.7
59
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
10.9
57.6
113
110
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
3.0
52.7
351
1355
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
5.9
51.9
152
277
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.0
51.3
177
390
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
9.3
51.1
109
124
MAB10
NOMESCO Finland
External version
111.6
50.1
54
5
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
7.7
49.7
120
167
O61.0
ICD-10 Finland
Failed medical induction of labour
19.4
49.6
76
41
SPAT1357
SPAT
Monitoring of problem during pregnancy
5.6
47.9
148
287
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
7.7
47.8
115
159
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.4
47.2
255
843
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
4.1
46.7
196
524
SPAT1262
SPAT
Handing over of treatment supplies
3.2
45.1
260
899
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.7
44.7
162
375
SPAT1189
SPAT
Other ultrasound examination during pregnancy
5.0
44.2
151
328
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
3.9
44.0
197
557
WX320
NOMESCO Finland
Spinalanesthesy
2.8
44.0
334
1387
W85
ICPC
Gestational diabetes
4.2
43.5
179
469
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.0
41.7
845
5603
6570B
ICD-9 Finland
Polyhydramnios[POLYHYDRAMNION, SYNNYTYKSEN AIKANA]
+∞
40.8
39
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.3
40.6
129
258
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.0
40.4
262
977
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
6.9
39.6
102
156
O47.9
ICD-10 Finland
False labour, unspecified
14.5
39.4
67
48
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.6
37.5
303
1294
O20.0
ICD-10 Finland
Threatened abortion
5.8
37.2
109
198
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
7.3
37.1
91
130
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.8
36.5
127
281
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
7.6
36.3
87
120
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
7.3
36.1
89
128
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
5.1
35.9
117
241
O41.0
ICD-10 Finland
Oligohydramnios
+∞
35.5
34
*
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.9
35.4
120
258
A10AE04
ATC
insulin glargine; parenteral
3.8
35.0
160
458
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
34.4
717
4684
SPAT1263
SPAT
Sampling
1.9
33.8
736
4875
W92
ICPC
Compl labour/ delivery livebirth
7.1
33.8
85
126
WX234
NOMESCO Finland
Paracervical blockade
4.1
33.5
138
360
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
6.2
32.8
91
154
A10AA01
ATC
NA
5.1
32.8
108
225
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.1
32.8
430
2323
O02.1
ICD-10 Finland
Missed abortion
3.1
32.6
199
709
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
3.4
32.3
171
550
A10AA02
ATC
NA
5.0
32.3
108
229
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
323.0
32.0
32
*
O32.0
ICD-10 Finland
Maternal care for unstable lie
323.0
32.0
32
*
A10AE05
ATC
insulin detemir; parenteral
4.2
31.6
125
314
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
30.3
29
*
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
30.3
29
*
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
30.3
29
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
5.7
29.6
87
159
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
29.2
28
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.1
28.9
94
193
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
13.5
28.8
50
38
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
7.8
28.7
67
89
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
17.1
28.5
45
27
O81.4
ICD-10 Finland
Vacuum extractor delivery
2.7
28.3
216
881
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
28.2
27
*
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
5.7
28.0
82
149
H04AA01
ATC
glucagon; nasal, parenteral
4.7
27.2
96
216
8811
FHL
Cesarean section
3.5
26.6
128
382
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
46.5
26.5
32
7
103
Kela drug reimbursment
Diabetes, insulin-treated
2.4
26.5
257
1193
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.4
26.1
254
1178
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
+∞
26.1
25
*
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.2
25.8
289
1437
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
9.6
25.8
53
57
SPAT1301
SPAT
No procedures
1.9
25.7
478
2915
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
13.7
25.5
44
33
W90
ICPC
Uncompl labour/delivery livebirth
2.9
24.8
158
576
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
5.5
24.5
74
140
T89
ICPC
Diabetes insulin dependent
3.8
24.1
107
298
MAE00
NOMESCO Finland
Outlet vacuum delivery
2.6
23.8
183
747
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
8.3
23.7
53
66
Z36.8
ICD-10 Finland
Other antenatal screening
4.3
23.2
88
213
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
4.7
23.1
80
177
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.8
22.4
150
562
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
12.9
22.2
39
31
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
+∞
21.9
21
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
21.8
654
4599
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.7
21.2
95
267
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
9.2
21.1
44
49
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
3.2
21.1
113
366
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.0
21.0
130
464
MAA96
NOMESCO Finland
Other intrauterine operation on pregnant uterus or fetus
28.4
21.0
28
10
A10AE06
ATC
insulin degludec; parenteral
4.3
20.9
79
191
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
7.8
20.9
48
63
MAB20
NOMESCO Finland
Failed external version
111.4
20.6
22
*
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
7.8
20.4
47
62
Z39.1
ICD-10 Finland
Care and examination of lactating mother
4.2
20.4
78
191
W29
ICPC
Pregnancy symptom/complaint other
3.6
19.8
92
267
B01AB05
ATC
enoxaparin; parenteral
1.8
19.5
363
2184
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.5
19.4
69
157
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
18.8
18
*
MAX99
NOMESCO Finland
Assistance to normal delivery
1.9
18.5
300
1715
Z30.2
ICD-10 Finland
Sterilization
2.0
18.3
240
1265
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.2
18.1
98
320
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.7
17.9
51
91
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
3.1
17.9
103
352
O35.0
ICD-10 Finland
Maternal care for (suspected) central nervous system malformation in fetus
+∞
17.7
17
*
J01DB01
ATC
cefalexin; oral
1.7
17.7
1340
11774
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
7.6
17.7
41
55
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
17.3
1238
10657
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
17.3
190
927
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.3
17.2
90
287
SPAT1312
SPAT
General health counselling
1.6
17.1
523
3632
SPAT1307
SPAT
Psychosocial counselling and guidance
2.3
17.1
169
786
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
50.5
17.0
20
*
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
16.7
16
*
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
6.3
16.3
43
70
H3600, E103
ICD-10 Finland
NA
5.6
16.2
47
86
WX290
NOMESCO Finland
Other blockade of nerve
1.5
16.2
867
6892
SPAT1324
SPAT
Screening procedure
1.6
16.1
535
3789
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
11.8
16.1
29
25
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.7
16.1
71
199
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
9.1
15.9
33
37
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
9.6
15.9
32
34
G02CB01
ATC
bromocriptine; systemic
3.9
15.8
65
171
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
6.3
15.7
41
66
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
15.3
229
1265
A10BA02
ATC
metformin; oral
1.9
15.2
232
1292
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.4
15.2
134
589
SPAT1315
SPAT
Periodic health check-up of children and adolescents
2.7
15.0
108
424
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
15.0
701
5366
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
5.5
15.0
44
82
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
14.9
998
8273
SGA01
NOMESCO Finland
Tooth opening as first aid
1.8
14.8
312
1934
K02.1
ICD-10 Finland
Caries of dentine
1.5
14.7
1005
8362
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
14.6
484
3404
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
14.6
14
*
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
14.6
14
*
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
14.6
14
*
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
+∞
14.6
14
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
4.8
14.6
48
102
J01DA01
ATC
[U] cefalexin; systemic
1.5
14.5
1001
8333
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
151.3
14.5
15
*
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.8
14.4
288
1759
SPAT1192
SPAT
Gynaecological examination
1.7
14.3
325
2059
SPAT1310
SPAT
Counselling related to known health issue
1.6
14.1
459
3210
SPAT1240
SPAT
Therapeutic discussion
1.8
14.1
251
1471
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
8.2
13.8
30
37
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.8
13.7
45
96
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
8.0
13.6
30
38
MAA06
NOMESCO Finland
Amnioreduction
+∞
13.6
13
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
13.4
278
1714
R51.80
ICD-10 Finland
Headache
1.7
13.3
286
1782
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
13.3
189
1024
SPAT1303
SPAT
Counselling and guidance related to growth and development
6.5
12.9
33
52
SPAT1373
SPAT
Combined screening in early pregnancy
4.0
12.9
51
131
N02BE01
ATC
paracetamol; systemic, rectal
1.6
12.8
1318
11804
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
12.6
434
3065
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
4.3
12.6
46
110
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
12.5
12
*
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
12.5
12
*
O61.1
ICD-10 Finland
Failed instrumental induction of labour
20.2
12.5
18
9
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
131.0
12.4
13
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.7
12.4
85
325
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
3.8
12.4
52
141
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
3.5
12.3
57
168
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
12.3
210
1214
SPAT1153
SPAT
Removal of sutures
1.6
12.2
347
2330
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.8
12.2
206
1183
SPAT1283
SPAT
Restricted health certificate
1.5
12.0
465
3367
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.9
11.9
38
79
SPAT1391
SPAT
Counselling and guidance related to family situation
4.4
11.9
42
97
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
11.8
886
7349
W30
ICPC
Pregnancy, Medical examin/health eval complete
6.2
11.8
31
51
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
4.1
11.8
45
112
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.2
11.6
43
104
E66.9
ICD-10 Finland
Obesity, unspecified
2.8
11.6
76
282
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
8.2
11.6
25
31
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
3.2
11.5
60
193
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
+∞
11.5
11
*
MA2BG
NOMESCO Finland
Fetal examination with high intensity magnet
+∞
11.5
11
*
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
+∞
11.5
11
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
3.4
11.4
55
167
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
120.8
11.4
12
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.5
11.3
51
147
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.6
11.3
388
2728
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
7.1
11.0
26
37
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
5.6
11.0
31
56
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.2
10.9
115
549
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
10.8
193
1131
SPAT1383
SPAT
Extensive health check-up at 4 years of age
4.9
10.7
34
71
P01AB01
ATC
metronidazole; oral, rectal
1.4
10.6
659
5231
XMA20
NOMESCO Finland
Early examination of pregnancy
3.6
10.6
46
129
O14.1
ICD-10 Finland
Severe pre-eclampsia
5.3
10.6
31
59
A02BC01
ATC
omeprazole; systemic
1.6
10.5
323
2206
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
5.7
10.4
29
52
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
4.9
10.2
32
66
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.0
10.2
130
675
Z36.2
ICD-10 Finland
Other antenatal screening based on amniocentesis
13.2
10.2
17
13
SPAT1393
SPAT
Guidance to support interaction between parent and child
7.7
9.9
22
29
W18
ICPC
Post-partum symptom/complaint other
6.3
9.9
25
40
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
5.5
9.8
28
52
O23.1
ICD-10 Finland
Infections of bladder in pregnancy
9.6
9.8
19
20
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
3.6
9.8
43
123
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
9.7
497
3788
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
4.5
9.6
33
75
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
9.5
101
485
O12.1
ICD-10 Finland
Gestational proteinuria
5.5
9.5
27
50
MA3AE
NOMESCO Finland
Combined first trimester screening
2.1
9.5
114
576
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
9.4
9
*
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
4.1
9.4
35
87
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
9.2
877
7454
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.6
9.1
39
109
W31
ICPC
Pregnancy, Medical examin/health eval partial
3.1
9.1
48
158
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
36.9
9.0
11
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.6
9.0
62
241
W27
ICPC
Fear of complications of pregnancy
4.1
9.0
33
81
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
6.5
9.0
22
34
MBA20
NOMESCO Finland
Expression of placenta
5.8
8.9
24
42
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
5.0
8.8
27
55
Z31.5
ICD-10 Finland
Genetic counselling
2.0
8.8
105
533
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
5.1
8.6
26
52
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.3
8.6
30
70
A10BK01
ATC
dapagliflozin; oral
3.2
8.6
44
142
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.9
8.6
116
617
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.6
8.6
59
230
MAG00
NOMESCO Finland
Assisted breech delivery
16.4
8.6
13
8
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
2.2
8.5
82
378
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.5
315
2235
SPAT1260
SPAT
Consultation of another employee
1.6
8.5
225
1475
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.5
786
6612
H01
ICPC
Ear pain/earache
1.7
8.5
188
1175
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.3
8.4
73
321
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
+∞
8.3
8
*
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
+∞
8.3
8
*
O33.2
ICD-10 Finland
Maternal care for disproportion due to inlet contraction of pelvis
+∞
8.3
8
*
6450B
ICD-9 Finland
Prolonged pregnancy[GRAVIDITAS PROLANGATA CUM PARTU]
+∞
8.3
8
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.2
8.3
79
364
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
4.6
8.3
27
59
B02AA02
ATC
tranexamic acid; systemic
1.5
8.3
291
2040
MAA10
NOMESCO Finland
Biopsy of chorionic villus
10.8
8.3
15
14
Z29
ICPC
Social problem NOS
3.7
8.2
34
93
C08CA05
ATC
nifedipine; systemic
2.5
8.2
61
248
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
8.2
96
481
WX110
NOMESCO Finland
Local anesthesy
1.4
8.2
1121
10013
SPAT1370
SPAT
Other health check-up
2.6
8.1
59
236
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.1
8.1
30
75
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
8.0
136
785
G03GB02
ATC
clomifene; oral
2.7
8.0
53
203
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
4.1
8.0
29
71
OAA12
SPAT
NA
2.8
7.9
47
168
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
0.5
7.9
52
1061
H3603, E103
ICD-10 Finland
NA
3.6
7.9
34
97
O72.0
ICD-10 Finland
Third-stage haemorrhage
2.5
7.9
58
235
EBA00
NOMESCO Finland
Extraction of tooth
1.4
7.9
463
3596
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.9
7.9
30
77
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.7
1120
10039
K04.0
ICD-10 Finland
Pulpitis
1.6
7.6
187
1201
O64.4
ICD-10 Finland
Obstructed labour due to shoulder presentation
25.1
7.6
10
*
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
8.9
7.5
15
17
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
7.5
155
950
SPAT1193
SPAT
Pap smear
1.5
7.5
279
1981
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.6
7.4
173
1098
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.5
7.4
32
92
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
2.3
7.3
63
276
6584B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, SYNNYTYKSEN AIKANA]
+∞
7.3
7
*
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
+∞
7.3
7
*
O32.8
ICD-10 Finland
Maternal care for other malpresentation of fetus
+∞
7.3
7
*
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
7.3
7
*
O36.2
ICD-10 Finland
Maternal care for hydrops fetalis
+∞
7.3
7
*
Z37.0
ICD-10 Finland
Single live birth
1.5
7.2
257
1804
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
6.3
7.2
18
29
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
7.2
173
1105
H3601, E103
ICD-10 Finland
NA
4.3
7.2
25
59
O47
ICD-10 Finland
False labour
4.6
7.2
23
50
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
3.8
7.2
28
74
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.5
7.1
236
1631
C07AG01
ATC
labetalol; systemic
3.3
7.1
34
106
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.3
7.1
34
106
SPAT1195
SPAT
Antenatal classes
2.1
7.1
79
390
M54.5
ICD-10 Finland
Low back pain
1.4
7.1
502
4012
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.9
7.0
103
565
HMAK
NOMESCO Finland
NA
1.5
7.0
215
1462
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.8
7.0
42
153
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
6.3
6.9
17
27
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.3
6.9
32
98
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
6.8
539
4378
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
6.8
185
1223
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
6.1
6.8
17
28
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
5.7
6.8
18
32
SPAT1389
SPAT
Visit based on need for special support
2.4
6.7
55
238
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.7
620
5151
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
6.7
110
627
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
2.9
6.7
37
128
WX600
NOMESCO Finland
Single shot through catheter
2.8
6.6
40
146
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.8
6.6
104
586
O62.0
ICD-10 Finland
Primary inadequate contractions
6.5
6.6
16
25
N05AH02
ATC
clozapine; systemic
0.1
6.6
*
222
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.6
6.6
46
181
SPAT1382
SPAT
Extensive health check-up at 18 months of age
4.4
6.5
22
51
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
6.5
129
781
SPAT1097
SPAT
Recording of ECG
1.7
6.5
117
691
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.3
6.5
18
34
Z37.1
ICD-10 Finland
Single stillbirth
70.1
6.4
7
*
CKC12
NOMESCO Finland
Photocoagulation of retina
2.4
6.4
49
204
Z82.7
ICD-10 Finland
Family history of congenital malformations, deformations and chromosomal abnormalities
6.6
6.3
15
23
Z22
ICPC
Illness problem parent/family memb
6.6
6.3
15
23
W05
ICPC
Pregnancy vomiting/nausea
3.5
6.3
27
78
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
2.6
6.3
43
170
25009
ICD-8 Finland
Diabetes mellitus, Unspecified
11.1
6.3
11
10
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
4.6
6.3
20
44
O43.0
ICD-10 Finland
Placental transfusion syndromes
+∞
6.3
6
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
6.3
6
*
6412B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Premature separation of placenta[ABLATIO PLACENTAE ANTETEMPUS,SYNN PÄÄTT HOITOJAKSO]
+∞
6.3
6
*
N61
ICD-10 Finland
Inflammatory disorders of breast
2.1
6.2
66
320
MAC98
NOMESCO Finland
Other induction of labor
26.8
6.2
8
*
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
4.8
6.2
19
40
SFA00
NOMESCO Finland
Small filling
1.5
6.2
182
1223
WX720
NOMESCO Finland
Own respiration
2.5
6.2
45
183
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.2
431
3421
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
7.0
6.2
14
20
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.4
6.2
337
2567
A05AA02
ATC
ursodeoxycholic acid; oral
3.0
6.2
32
107
SGB30
NOMESCO Finland
Other demanding filling of root channel of tooth
1.5
6.2
214
1497
G03DB01
ATC
dydrogesterone; oral
1.4
6.1
291
2162
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.5
6.1
179
1201
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
8.6
6.1
12
14
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
4.4
6.0
20
46
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.2
6.0
21
51
O21
ICD-10 Finland
Excessive vomiting in pregnancy
4.2
6.0
21
51

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
365
1351
3.10
73.85
1.6
1.3
—
—
—
0
0
133
257
5.49
65.99
1.8
1.5
7.8
7.7
mmol/l
0.26
70
147
471
2125
2.62
64.85
2.1
1.9
—
—
—
0
0
771
4423
2.25
61.14
1.9
1.7
—
—
—
0
0
667
3645
2.28
59.10
1.7
1.6
—
—
—
0
0
145
376
4.09
50.07
2.3
2.1
4.1
5.8
umol/l
0.94
112
293
1038
7184
1.98
45.45
4.6
3.7
6.6
6.2
mmol/l
4.98
881
6559
992
7151
1.81
34.47
4.4
3.5
—
—
—
0
0
363
1908
2.11
32.77
2.6
2.1
9374.6
5366.3
u/l
1.37
170
704
600
3891
1.79
28.37
4.1
3.2
0.0
0.0
estimate
1.08
212
1455
1259
10053
1.74
27.83
4.7
3.5
86.8
1512.4
e6/l
2.93
12
107
500
3128
1.81
26.34
4.1
3.1
1.0
1.0
kg/l
0.79
102
429
1298
10557
1.72
25.73
4.7
3.7
—
—
—
0
0
587
3910
1.72
24.60
2.6
2.2
—
—
—
0
0
1005
7713
1.64
24.28
4.1
3.0
0.0
0.0
estimate
1.79
215
1446
997
7647
1.64
24.05
5.4
4.3
0.0
0.0
estimate
0.80
219
1478
992
7625
1.63
23.52
4.0
3.0
0.0
0.0
estimate
0.50
214
1420
790
5767
1.63
22.90
2.0
2.0
—
—
—
0
0
407
2500
1.80
22.32
4.8
4.1
8.5
12.2
mg/mmol
1.02
306
1588
387
2419
1.75
19.74
3.8
3.4
205.8
398.3
mg/l
0.52
276
1484
624
4548
1.55
16.88
3.5
2.6
—
—
—
0
0
36
75
4.87
16.39
3.6
2.1
—
—
—
0
0
59
180
3.35
16.06
2.9
2.6
53.6
117.6
ug/min
0.86
45
124
1134
9437
1.50
15.92
3.4
3.0
59.1
61.1
ug/l
0.30
1089
9038
1652
15030
1.74
14.99
9.9
8.9
139.5
139.5
mmol/l
0.05
1619
14578
1655
15074
1.74
14.84
10.0
8.9
3.9
3.9
mmol/l
0.04
1620
14591
550
3995
1.53
14.72
2.9
2.5
55.1
54.3
u/l
0.07
531
3715
66
231
2.92
14.30
4.0
3.4
—
—
—
0
0
43
115
3.80
14.26
1.4
1.3
—
—
—
0
0
1538
13801
1.59
14.02
5.0
4.3
14.3
14.2
pmol/l
0.51
1465
13047
453
3184
1.55
13.97
3.6
3.2
8.1
7.6
mmol/l
1.36
402
2773
502
3703
1.48
12.07
2.5
2.4
26.8
22.5
ng/l
0.16
177
1397
496
3689
1.47
11.33
4.8
4.9
1.0
1.1
inr
0.43
174
1305
679
5364
1.41
11.13
2.2
1.6
—
—
—
0
0
118
611
1.99
10.73
1.3
1.1
—
—
—
0
0
1666
15473
1.60
10.58
5.8
4.9
1.6
1.9
mu/l
1.72
1598
14804
61
241
2.58
10.57
2.5
2.6
—
—
—
0
0
1809
17192
2.01
10.55
11.4
8.7
—
—
—
0
0
572
4419
1.42
10.51
2.1
1.9
—
—
—
0
0
61
251
2.48
9.74
1.1
1.1
10.5
1293.5
iu/ml
0.55
21
64
34
105
3.28
9.18
1.5
1.3
—
—
—
0
0
93
475
2.01
8.83
4.8
6.5
23.7
24.3
mmol/l
0.76
83
440
234
1577
1.55
8.41
1.8
1.6
—
—
—
0
0
175
1102
1.65
8.35
1.4
1.3
—
—
—
0
0
1412
12865
1.38
8.30
5.8
3.9
39.9
37.0
mmol/mol
17.38
1346
12277
584
4674
1.36
8.30
1.4
1.3
1.1
1.4
u/ml
0.74
178
1355
100
543
1.89
7.97
3.9
2.7
—
—
—
0
0
70
335
2.13
7.93
1.4
1.3
—
—
—
0
0
460
3567
1.38
7.91
1.8
1.7
0.8
0.7
mg/l
0.64
361
2606
53
226
2.38
7.89
1.2
1.3
—
—
—
0
0
348
2574
1.43
7.87
1.6
1.5
92026992.4
29011415.0
pmol/l
0.71
301
2275
464
3621
1.37
7.64
2.5
2.1
2.7
2.7
mg/l
0.04
410
3122
425
3274
1.38
7.57
1.3
1.3
23.6
22.4
iu/ml
0.10
132
1004
1699
16070
1.52
7.52
11.4
9.5
16.7
18.1
mg/l
1.25
1421
12022
66
318
2.11
7.37
1.4
1.4
111.7
115.6
u/ml
0.18
20
62
688
5729
1.31
7.24
6.2
5.3
1.2
1.2
mmol/l
0.06
585
4866
88
475
1.89
7.17
3.5
4.6
—
—
—
0
0
178
1171
1.57
7.11
1.5
1.3
—
—
—
0
0
70
351
2.03
7.05
3.5
3.3
0.2
0.4
g/l
1.37
33
141
56
258
2.21
7.01
1.6
1.9
1.1
2.6
ug/l
0.60
47
224
389
3004
1.37
6.75
2.2
2.0
283.7
2724.3
umol/l
5.68
342
2707
327
2460
1.40
6.64
3.2
3.7
—
—
—
0
0
1880
18354
2.66
6.62
16.9
14.5
267.0
274.1
e9/l
5.69
1859
17991
398
3096
1.36
6.58
1.4
1.3
8.0
11.0
u/ml
0.49
175
1341
60
294
2.07
6.45
3.4
4.9
1.4
1.2
mmol/l
1.31
51
257
1880
18372
2.59
6.27
16.8
14.4
29.8
29.9
pg
3.66
1872
18208
1880
18376
2.57
6.19
16.9
14.5
4.5
4.5
e12/l
1.67
1860
18004
1880
18381
2.55
6.10
16.9
14.5
6.9
6.7
e9/l
3.97
1857
17989
1880
18387
2.53
5.98
17.0
14.5
131.9
133.4
g/l
7.22
1871
18219
1879
18373
2.49
5.98
16.8
14.4
89.3
90.0
fl
8.64
1872
18211
186
1286
1.49
5.93
3.4
3.1
—
—
—
0
0
397
3140
1.33
5.82
1.9
2.0
114.8
147.5
u/l
0.66
386
2989
1164
10553
1.26
5.70
6.7
6.4
72.6
70.8
u/l
0.98
1098
9995
28
103
2.74
5.70
3.9
4.7
6.7
7.7
mmol/l
0.29
23
85
763
6603
1.26
5.53
4.9
5.0
8.9
9.3
umol/l
0.90
725
6189
31
126
2.48
5.21
1.1
1.1
1.1
1.0
ratio
—
8
52
1522
14325
1.31
5.20
13.0
11.8
13.4
13.5
%
1.94
1496
14064
302
2330
1.35
5.19
3.0
2.4
540.1
531.1
mosm/kgh2o
0.24
263
1985
135
898
1.54
5.18
3.4
2.3
—
—
—
0
0
236
1751
1.40
5.17
2.2
2.5
1016.2
417.5
ng/l
0.66
197
1397
604
5136
1.26
4.97
4.7
4.1
36.5
37.1
g/l
1.90
577
4795
216
1596
1.40
4.85
1.2
1.2
—
—
—
0
0
132
888
1.52
4.83
3.7
3.0
1.2
1.2
mmol/l
1.83
111
773
355
2833
1.31
4.82
2.6
2.5
—
—
—
0
0
417
3412
1.28
4.68
4.1
3.0
—
—
—
0
0
1740
16774
1.42
4.57
9.0
8.0
23.7
23.5
u/l
0.27
1698
16360
994
8991
1.22
4.43
2.6
2.6
—
—
—
0
0
316
2512
1.31
4.40
2.8
2.3
7.9
9.7
e6/l
1.06
276
2189
113
751
1.54
4.39
6.5
7.4
122.3
122.0
g/l
0.07
108
724
129
883
1.49
4.37
4.0
3.2
—
—
—
0
0
116
783
1.51
4.21
6.3
7.1
96.6
96.3
%
0.19
110
753
18
62
2.92
4.17
1.2
1.1
—
—
—
0
0
25
103
2.45
4.14
1.2
1.1
—
34.1
—
0
10
254
1984
1.32
4.00
2.7
2.3
14.5
14.6
umol/l
0.06
237
1865
20
75
2.68
3.99
1.6
1.8
0.7
3.6
u/field
—
9
39
318
2571
1.28
3.88
1.4
1.4
405.8
600.1
titre
1.53
48
526
79
505
1.59
3.68
2.1
2.2
6.0
3.8
iu/l
0.71
30
224
24
103
2.35
3.67
1.1
1.1
1275.3
1573.5
miu/ml
0.77
24
103
765
6833
1.20
3.64
8.0
7.7
0.0
0.0
e9/l
0.87
676
5606
50
284
1.78
3.62
3.9
4.9
—
—
—
0
0
1216
11341
1.20
3.53
4.1
3.6
9.2
9.2
mm/h
0.08
1158
10685
226
1772
1.31
3.48
2.6
2.3
2.6
2.5
g/l
0.88
207
1662
111
777
1.46
3.42
3.5
3.7
2.1
1.7
mmol/l
0.78
85
612
144
1059
1.39
3.37
6.7
6.3
104.9
104.9
mmol/l
0.09
139
1042
38
203
1.89
3.35
4.1
2.5
—
—
—
0
0
61
375
1.65
3.35
1.3
1.2
259.9
273.3
u/ml
0.17
40
255
199
1542
1.32
3.34
1.9
2.0
28.6
29.2
s
1.27
192
1483
129
940
1.40
3.20
6.2
6.5
1.1
0.6
mmol/l
0.80
83
698
91
621
1.49
3.20
1.4
1.4
23.8
21.6
u/l
0.23
69
520
53
319
1.68
3.17
1.9
2.0
1.2
1.3
g/l
0.34
44
272
17
67
2.55
3.13
1.2
1.5
1.0
2.6
u/field
1.29
12
48
47
275
1.73
3.12
4.3
3.1
21.1
20.7
mg/l
0.03
37
172
208
1638
1.30
3.11
1.9
2.1
377.4
374.0
nmol/l
0.09
187
1509
212
1676
1.30
3.09
1.9
1.8
—
—
—
0
0
427
3665
1.21
3.02
3.3
2.7
19.7
84.0
e6/l
2.09
334
2715
127
935
1.38
2.99
6.3
6.4
4.8
5.0
kpa
3.11
120
893
127
935
1.38
2.99
6.3
6.4
13.1
13.9
kpa
0.94
120
892
5
177
0.28
2.97
1.2
1.4
—
—
—
0
0
76
510
1.51
2.92
2.1
2.0
2.1
5.0
ug/l
5.41
65
443
105
752
1.42
2.90
1.3
1.2
—
—
—
0
0
220
1772
1.27
2.78
1.7
1.6
1226.5
1187.1
nmol/l
0.27
194
1375
9
23
3.93
2.77
1.0
1.1
—
—
—
0
0
237
2883
0.80
2.73
1.3
1.3
—
—
—
0
0
91
643
1.44
2.72
1.9
2.5
66.9
72.9
e9/l
0.89
75
456
57
365
1.58
2.72
3.3
2.9
0.8
0.7
%
1.01
50
356
25
127
1.98
2.60
1.0
1.4
—
—
—
0
0
25
127
1.98
2.60
1.0
1.4
—
—
—
0
0
25
127
1.98
2.60
1.0
1.4
—
—
—
0
0
25
127
1.98
2.60
1.0
1.4
—
—
—
0
0
106
778
1.38
2.58
1.2
1.3
0.6
1.5
u/ml
—
10
66
161
1259
1.30
2.57
6.7
5.4
1.0
1.0
mmol/l
0.09
151
1193
569
5079
1.17
2.54
5.4
4.6
1.2
1.2
mmol/l
1.65
514
4657
20
95
2.12
2.49
1.2
1.9
—
—
—
0
0
307
2605
1.21
2.43
1.5
1.4
19.9
20.8
nmol/l
0.56
277
2353
42
258
1.64
2.40
4.1
3.5
0.8
0.9
nmol/l
0.45
32
224
8
22
3.65
2.36
1.4
1.4
22.2
40.3
%
—
8
17
38
605
0.62
2.27
1.3
1.3
—
—
—
0
0
63
433
1.47
2.23
1.4
1.6
—
—
—
0
0
220
1821
1.24
2.23
2.3
2.7
746.1
327.6
ng/l
0.29
98
850
20
100
2.01
2.21
1.2
1.8
3.9
3.9
mmol/l
0.00
20
100
20
100
2.01
2.21
1.2
1.8
105.2
105.8
mmol/l
0.21
20
100
6
14
4.30
2.15
6.8
2.5
—
—
—
0
0
24
131
1.84
2.08
1.2
1.2
—
—
—
0
0
130
1641
0.78
2.07
1.2
1.3
—
—
—
0
0
377
3307
1.17
2.06
2.1
1.8
—
—
—
0
0
25
140
1.80
2.01
1.4
2.1
5.6
37.2
u/ml
0.49
20
116
193
1599
1.23
1.96
2.7
2.4
24.2
24.1
%
0.03
163
1403
77
567
1.37
1.91
2.0
2.0
20.9
20.6
s
0.38
54
480
62
445
1.41
1.80
9.0
8.4
—
—
—
0
0
377
3346
1.16
1.78
3.2
2.6
0.2
0.3
e6/l
1.37
302
2420
153
1851
0.81
1.72
1.6
1.7
—
—
—
0
0
133
1079
1.25
1.67
1.6
1.3
—
—
—
0
0
172
1435
1.22
1.66
3.2
3.4
4.5
4.5
pmol/l
0.14
157
1276
7
25
2.81
1.65
1.3
1.1
—
—
—
0
0
1496
14514
1.14
1.62
3.5
3.3
5.8
5.5
mmol/l
8.71
1416
13754
384
3437
1.15
1.61
4.2
3.5
7.4
7.4
ph
0.27
78
637
133
1087
1.24
1.57
1.6
1.3
—
—
—
0
0
69
519
1.34
1.54
3.2
2.8
5.1
5.1
kpa
0.05
62
489
31
200
1.56
1.54
4.6
2.6
2.4
2.4
mmol/l
0.03
21
119
68
511
1.34
1.53
3.2
2.7
7.4
7.4
ph
—
7
75
17
93
1.84
1.51
2.2
1.4
—
—
—
0
0
327
2908
1.15
1.51
1.6
1.6
—
—
—
0
0
342
3819
0.87
1.51
5.8
6.7
—
—
—
0
0
19
108
1.77
1.50
1.5
1.2
—
40.7
—
0
11
6
21
2.86
1.50
1.0
1.5
—
—
—
0
0
111
1364
0.80
1.47
3.1
2.3
28.4
34.2
u/l
1.54
93
1167
31
462
0.67
1.46
1.3
1.1
—
—
—
0
0
31
462
0.67
1.46
1.3
1.1
—
—
—
0
0
68
516
1.33
1.45
1.9
2.4
78.8
83.8
ng/l
0.09
60
453
36
244
1.48
1.45
1.0
1.1
—
—
—
0
0
135
1117
1.22
1.44
3.5
4.5
0.0
0.1
%
0.78
29
242
5
16
3.13
1.44
17.0
4.4
—
—
—
0
0
42
295
1.43
1.42
1.1
1.2
—
—
—
0
0
377
3400
1.14
1.42
1.8
1.6
1.3
1.3
mmol/l
0.03
323
3018
10
46
2.18
1.40
1.1
1.1
—
—
—
0
0
10
46
2.18
1.40
1.1
1.1
—
—
—
0
0
10
46
2.18
1.40
1.1
1.1
—
—
—
0
0
117
961
1.23
1.35
1.1
1.1
—
—
—
0
0
0
38
0.00
1.34
0.0
8.0
—
—
—
0
0
133
1115
1.21
1.27
1.7
1.4
—
—
—
0
0
10
48
2.09
1.27
1.5
2.5
—
—
—
0
0
115
957
1.21
1.20
2.3
2.4
1.6
1.7
%
0.37
102
838
115
958
1.21
1.19
1.7
2.0
—
—
—
0
0
8
38
2.11
1.18
1.4
1.6
—
—
—
0
0
29
198
1.47
1.17
1.7
1.6
—
—
—
0
0
137
1165
1.19
1.15
3.4
4.4
1.2
0.8
%
0.25
29
263
304
3355
0.89
1.13
4.0
3.1
98.0
99.2
%
0.42
290
3252
48
629
0.76
1.12
1.8
1.8
—
—
—
0
0
136
1164
1.18
1.07
1.9
2.5
10.4
10.6
g/l
0.20
131
1082
23
153
1.51
1.06
1.2
1.2
—
—
—
0
0
369
3385
1.11
1.06
2.9
2.5
—
—
—
0
0
9
46
1.96
1.03
1.3
1.3
—
—
—
0
0
96
800
1.21
1.02
4.5
3.7
80.2
75.6
ng/l
0.18
84
722
126
1078
1.18
1.01
3.4
4.2
1.2
0.7
%
0.35
23
188
38
506
0.75
1.01
1.3
1.3
—
—
—
0
0
5
110
0.45
1.00
2.2
2.9
321.2
730.8
u/ml
—
5
110
1155
11920
0.92
1.00
2.8
2.7
33.7
31.6
u/l
0.43
1104
11483
7
35
2.00
1.00
1.7
1.1
99.5
63.2
nmol/l
—
7
25
149
1708
0.86
0.99
1.3
1.3
—
—
—
0
0
31
223
1.40
0.98
1.0
1.0
—
—
—
0
0
23
156
1.48
0.98
3.3
2.2
—
—
—
0
0
7
36
1.95
0.97
1.1
1.1
—
—
—
0
0
0
31
0.00
0.96
0.0
2.0
—
—
—
0
0
77
632
1.23
0.96
1.8
1.7
—
—
—
0
0
126
1084
1.17
0.96
3.6
4.5
0.0
0.4
%
0.58
25
203
338
3107
1.11
0.94
1.4
1.5
—
—
—
0
0
6
119
0.50
0.93
1.3
1.4
9.5
9.4
umol/l
—
6
110
36
269
1.34
0.92
1.1
1.1
—
—
—
0
0
456
4259
1.09
0.91
3.6
4.0
—
—
—
0
0
428
3988
1.09
0.90
1.4
1.4
2.0
2.1
g/l
1.43
295
2615
170
1913
0.88
0.89
1.5
1.5
—
—
—
0
0
86
1020
0.84
0.88
1.6
1.4
—
—
—
0
0
652
6855
0.93
0.87
1.9
1.9
—
—
—
0
0
40
307
1.31
0.87
1.2
1.3
2.5
3.3
u/ml
0.66
14
124
6
30
2.00
0.87
1.5
1.8
—
—
—
0
0
20
136
1.48
0.86
1.1
1.1
—
—
—
0
0
516
4860
1.08
0.85
3.8
3.2
48.4
58.3
e6/l
0.28
368
3028
58
470
1.24
0.84
1.3
1.9
—
—
—
0
0
1559
15320
1.10
0.84
3.8
3.2
4.8
4.8
mmol/l
0.50
1493
14720
100
856
1.18
0.83
1.3
1.3
—
—
—
0
0
44
345
1.28
0.83
1.1
1.2
—
—
—
0
0
1569
15427
1.10
0.82
4.0
3.4
2.9
2.9
mmol/l
0.97
1490
14708
14
213
0.65
0.81
1.4
1.9
41.5
39.3
g/l
3.97
14
195
32
241
1.33
0.80
1.6
1.6
—
—
—
0
0
13
200
0.65
0.80
1.1
1.1
—
—
—
0
0
44
552
0.79
0.79
1.3
1.2
—
—
—
0
0
20
139
1.44
0.79
1.2
1.2
—
—
—
0
0
103
889
1.17
0.79
1.4
1.8
1.2
1.3
g/l
0.47
96
827
0
26
0.00
0.78
0.0
1.1
—
—
—
0
0
102
881
1.17
0.78
2.0
2.5
—
—
—
0
0
68
812
0.83
0.77
1.0
1.1
—
—
—
0
0
170
1523
1.13
0.77
3.1
2.2
6.8
5.2
umol/l
0.45
145
1258
6
34
1.77
0.76
1.3
1.7
—
—
—
0
0
42
524
0.80
0.73
1.3
1.1
—
—
—
0
0
153
1370
1.13
0.71
1.3
1.3
124.1
232.4
u/ml
0.81
138
1271
13
85
1.53
0.69
1.3
1.2
—
—
—
0
0
9
59
1.53
0.68
2.4
1.8
—
144.1
—
0
8
106
931
1.15
0.67
5.8
9.8
1.2
1.1
inr
0.28
18
173
1548
15250
1.08
0.66
3.8
3.2
1.5
1.6
mmol/l
8.41
1479
14611
515
4907
1.07
0.63
1.8
1.7
97.3
100.3
pmol/l
0.81
294
2708
5
30
1.67
0.61
1.2
3.0
—
—
—
0
0
194
1779
1.10
0.61
3.6
3.1
0.8
0.8
mmol/l
0.94
183
1677
13
88
1.48
0.60
1.0
1.1
—
—
—
0
0
0
23
0.00
0.58
0.0
1.0
—
—
—
0
0
24
184
1.31
0.58
3.3
1.8
26.3
46.8
mu/l
1.49
24
167
42
346
1.22
0.57
1.3
1.3
302.4
314.3
ug/g
0.10
20
174
21
158
1.33
0.57
1.3
1.5
—
—
—
0
0
25
194
1.29
0.56
1.7
1.3
—
—
—
0
0
8
125
0.64
0.54
1.6
1.6
30.2
22.2
umol/l
—
8
117
61
707
0.86
0.54
1.3
1.5
0.6
0.5
nmol/l
0.34
52
577
6
38
1.58
0.54
1.0
2.1
11.1
21.7
ug/l
—
6
38
747
7714
0.95
0.54
5.2
5.7
57.4
56.4
%
1.92
701
7316
14
99
1.42
0.54
1.0
1.0
—
—
—
0
0
216
2006
1.09
0.53
1.2
1.2
137.9
159.6
iu/ml
0.40
87
802
11
74
1.49
0.53
2.8
2.8
10.1
11.1
%
0.51
11
74
22
169
1.31
0.53
1.4
1.4
0.4
0.4
g/l
0.21
13
114
22
169
1.31
0.53
1.4
1.4
3.2
3.0
g/l
0.18
13
114
198
1833
1.09
0.53
1.2
1.2
—
—
—
0
0
34
277
1.23
0.52
3.4
2.2
—
—
—
0
0
755
7789
0.95
0.52
5.2
5.8
29.3
29.9
%
1.18
713
7375
41
341
1.21
0.52
3.0
2.9
—
—
—
0
0
22
170
1.30
0.51
1.4
1.4
6.8
6.1
g/l
0.60
13
116
22
170
1.30
0.51
1.5
1.4
—
—
—
0
0
124
1124
1.11
0.51
1.4
1.3
278.7
244.9
miu/ml
0.41
60
595
11
75
1.47
0.50
1.0
1.2
—
—
—
0
0
42
498
0.84
0.50
1.0
1.2
—
—
—
0
0
189
2034
0.92
0.49
2.1
2.3
2.4
2.4
mmol/l
0.11
170
1777
26
323
0.80
0.49
2.9
3.3
3.9
4.0
e9/l
0.09
26
323
20
154
1.30
0.48
1.1
1.0
—
—
—
0
0
24
191
1.26
0.46
3.8
1.9
16.1
16.9
%
0.35
13
100
411
4293
0.95
0.45
2.9
3.1
2.3
2.3
mmol/l
0.40
380
3914
7
51
1.37
0.44
1.1
1.2
—
—
—
0
0
9
127
0.71
0.43
1.0
1.1
—
—
—
0
0
691
6709
1.05
0.43
2.7
2.1
—
—
—
0
0
27
328
0.82
0.43
3.0
3.5
56.6
56.7
%
0.02
27
328
14
184
0.76
0.41
2.1
2.0
—
—
—
0
0
123
1131
1.09
0.41
1.2
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
5.7
—
0.3
—
0
15
8
59
1.36
0.41
2.8
2.6
7.0
7.3
%
—
8
59
8
59
1.36
0.41
2.5
2.5
—
—
—
0
0
0
17
0.00
0.40
0.0
4.5
—
—
—
0
0
94
854
1.11
0.40
1.2
1.3
14.5
10.5
u/l
1.71
81
694
7
105
0.67
0.39
1.1
1.2
—
—
—
0
0
0
19
0.00
0.39
0.0
1.1
—
0.2
—
0
7
15
115
1.31
0.39
1.3
1.2
—
—
—
0
0
21
169
1.25
0.38
1.0
1.0
—
—
—
0
0
64
572
1.12
0.37
1.1
1.1
5.8
1.3
u/ml
0.91
22
223
159
1487
1.08
0.37
1.3
1.3
—
—
—
0
0
118
1092
1.09
0.36
1.1
1.1
196.7
120.2
titre
—
6
26
700
7175
0.96
0.35
5.3
5.9
0.6
0.7
%
0.85
661
6752
6
44
1.36
0.34
1.3
1.4
—
—
—
0
0
21
172
1.22
0.34
1.4
1.9
18.6
20.0
nmol/l
0.41
21
166
20
163
1.23
0.34
1.1
3.2
28.9
24.3
mg/l
0.18
14
135
20
163
1.23
0.34
1.1
3.2
52.8
33.0
mg/l
0.43
14
137
32
371
0.86
0.33
2.1
2.3
—
—
—
0
0
6
46
1.31
0.33
5.5
2.2
—
—
—
0
0
21
173
1.22
0.33
1.1
1.3
—
—
—
0
0
130
1214
1.08
0.33
1.7
2.3
3.9
4.1
e9/l
0.46
112
1030
125
1167
1.08
0.32
1.7
1.9
—
—
—
0
0
12
92
1.31
0.31
1.1
1.5
5.2
5.4
u/l
0.07
12
76
15
119
1.26
0.31
1.1
3.3
—
—
—
0
0
727
7430
0.97
0.31
5.2
5.9
2.7
2.7
%
0.14
684
6992
7
52
1.35
0.31
2.7
1.4
—
—
—
0
0
93
859
1.09
0.31
3.7
3.5
57.7
51.0
ug/l
0.03
66
605
68
746
0.91
0.31
1.7
1.7
—
—
—
0
0
1619
16072
1.05
0.30
11.5
10.5
38.7
39.7
%
5.18
1244
13737
38
334
1.14
0.30
1.3
1.6
—
5.3
—
0
9
7
55
1.27
0.30
1.3
1.1
—
—
—
0
0
731
7464
0.97
0.30
5.4
6.1
7.7
7.9
%
0.91
693
7088
136
1279
1.07
0.29
1.6
1.7
—
—
—
0
0
134
1260
1.07
0.29
2.3
2.3
12.2
24.5
au/ml
—
9
98
34
387
0.88
0.29
1.1
1.3
—
—
—
0
0
806
8212
0.97
0.29
5.2
5.9
2.0
2.0
e9/l
0.93
747
7457
135
1273
1.07
0.27
1.6
1.9
—
—
—
0
0
1478
14654
1.04
0.27
3.4
3.0
1.2
1.2
mmol/l
0.55
1410
14035
8
64
1.25
0.27
3.3
2.2
—
—
—
0
0
192
2012
0.95
0.27
1.2
1.2
—
—
—
0
0
59
538
1.10
0.27
2.2
2.1
—
—
—
0
0
468
4806
0.97
0.26
5.2
6.0
—
—
—
0
0
128
1207
1.06
0.26
1.3
1.2
—
—
—
0
0
136
1287
1.06
0.25
1.6
1.9
—
—
—
0
0
9
72
1.25
0.25
1.4
2.3
—
—
—
0
0
9
72
1.25
0.25
2.6
2.3
50.8
62.8
nmol/l
—
9
72
52
473
1.10
0.25
1.5
1.4
5.7
6.6
u/ml
—
5
57
9
74
1.22
0.25
1.2
1.2
—
—
—
0
0
36
321
1.12
0.24
1.2
1.2
—
—
—
0
0
179
1869
0.95
0.23
3.0
2.5
5.7
5.0
e6/l
0.30
104
922
173
1655
1.05
0.23
1.5
1.5
—
—
—
0
0
13
106
1.23
0.23
1.8
1.8
37.4
47.8
%
—
8
68
11
136
0.81
0.23
1.5
1.4
0.9
0.9
g/l
0.02
11
136
5
39
1.28
0.23
1.0
1.0
—
—
—
0
0
155
1482
1.05
0.21
1.5
1.7
288.1
326.4
mu/l
0.72
133
1317
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
2.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
10
0.00
0.21
0.0
3.1
—
—
—
0
0
905
8930
1.03
0.21
7.0
8.9
4.2
4.0
e9/l
1.40
822
7942
0
12
0.00
0.21
0.0
1.3
—
72.2
—
0
12
0
12
0.00
0.21
0.0
2.1
—
1.1
—
0
7
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
355.5
—
0
13
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
0
14
0.00
0.20
0.0
2.3
—
210.1
—
0
14
1526
15168
1.03
0.19
14.1
12.1
332.6
331.8
g/l
3.27
1520
15028
133
1271
1.05
0.19
1.6
1.9
—
—
—
0
0
17
197
0.86
0.19
1.8
1.3
—
—
—
0
0
14
118
1.19
0.19
2.1
3.6
—
—
—
0
0
21
184
1.14
0.19
1.2
1.5
—
—
—
0
0
6
53
1.13
0.18
1.3
1.2
—
—
—
0
0
13
109
1.19
0.18
1.2
1.5
—
—
—
0
0
108
1030
1.05
0.18
3.4
3.1
—
—
—
0
0
11
131
0.84
0.17
1.0
1.1
—
—
—
0
0
7
63
1.11
0.17
1.0
1.1
—
—
—
0
0
5
67
0.75
0.17
1.2
2.2
29.6
29.4
umol/l
—
5
62
5
68
0.73
0.17
1.2
1.4
—
5.6
—
0
9
218
2116
1.03
0.16
1.2
1.3
24.1
23.7
iu/l
0.06
193
1815
8
68
1.18
0.16
3.1
3.0
—
—
—
0
0
8
72
1.11
0.16
1.4
1.6
2.8
2.6
mg/l
—
8
66
48
448
1.07
0.15
1.0
1.1
1.9
4.3
u/ml
0.55
15
164
40
372
1.08
0.14
1.4
1.3
—
—
—
0
0
8
96
0.83
0.13
1.8
1.2
—
63.3
—
0
12
20
180
1.11
0.13
1.2
1.7
—
—
—
0
0
9
108
0.83
0.13
2.2
1.3
—
—
—
0
0
18
161
1.12
0.13
3.4
3.4
39.8
35.1
u/ml
0.12
18
161
10
85
1.18
0.12
1.1
1.1
—
—
—
0
0
20
181
1.11
0.12
1.0
1.0
—
0.4
—
0
54
55
522
1.06
0.12
1.0
1.1
3.3
5.7
u/ml
0.77
22
283
46
434
1.06
0.12
5.8
4.0
24.2
24.1
mmol/l
0.07
37
396
11
95
1.16
0.11
1.5
3.1
—
—
—
0
0
43
406
1.06
0.11
1.0
1.1
5.2
3.9
u/ml
0.19
13
162
272
2673
1.02
0.10
2.5
2.4
125.7
97.5
ug/g
0.55
219
2065
5
44
1.14
0.10
5.2
5.1
—
—
—
0
0
5
45
1.11
0.09
1.0
1.2
—
—
—
0
0
19
207
0.92
0.09
1.2
1.1
—
—
—
0
0
17
155
1.10
0.09
2.2
2.8
1.3
1.2
e9/l
—
7
88
14
126
1.11
0.09
1.4
1.6
—
—
—
0
0
51
489
1.04
0.08
1.0
1.1
0.4
0.9
u/ml
0.95
15
215
17
185
0.92
0.08
7.4
3.0
—
—
—
0
0
13
117
1.11
0.08
1.2
1.1
—
—
—
0
0
6
75
0.80
0.07
1.0
2.0
0.2
1.4
ug/l
—
6
69
8
74
1.08
0.07
1.5
1.7
121.9
133.3
nmol/l
—
8
74
8
75
1.07
0.07
3.3
2.3
—
—
—
0
0
7
80
0.87
0.07
1.0
1.3
—
—
—
0
0
7
84
0.83
0.07
1.1
1.1
—
—
—
0
0
49
509
0.96
0.07
1.0
1.1
1.4
1.2
u/ml
0.09
11
117
9
85
1.06
0.07
2.0
1.8
—
—
—
0
0
9
105
0.86
0.06
1.4
1.3
—
223.2
—
0
22
9
105
0.86
0.06
1.6
1.5
—
—
—
0
0
55
533
1.03
0.06
2.1
2.5
—
—
—
0
0
14
129
1.09
0.05
4.7
7.6
—
—
—
0
0
24
228
1.05
0.05
1.7
2.3
—
—
—
0
0
22
232
0.95
0.05
1.1
1.8
—
28.7
—
0
12
785
7884
0.99
0.05
5.2
5.9
0.5
0.5
e9/l
1.01
718
7047
13
120
1.08
0.05
1.7
1.4
0.6
1.1
promille
—
8
95
37
357
1.04
0.04
1.2
1.3
1.0
1.5
nmol/l
2.01
29
290
29
302
0.96
0.04
2.1
1.8
—
—
—
0
0
10
91
1.10
0.04
2.2
3.1
—
—
—
0
0
39
378
1.03
0.04
1.1
1.1
—
—
—
0
0
822
8193
1.01
0.03
5.2
6.3
0.2
0.2
e9/l
0.61
762
7414
789
7915
0.99
0.03
5.2
5.9
0.0
0.0
e9/l
0.71
720
7051
40
390
1.03
0.02
1.1
1.0
0.9
2.2
u/ml
3.65
23
241
25
259
0.96
0.02
1.6
1.6
0.8
0.7
g/l
0.30
15
189
13
138
0.94
0.02
2.5
2.4
47.0
46.0
%
—
5
23
135
1338
1.01
0.02
1.9
2.3
21.6
35.6
u/ml
3.39
129
1296
198
1969
1.01
0.01
2.8
2.3
1.0
1.1
e6/l
0.12
121
1016
13
124
1.05
0.00
1.8
2.7
523.9
477.0
e6/l
0.23
13
102
70
706
0.99
0.00
10.0
7.8
—
—
—
0
0
11
115
0.96
0.00
2.5
2.3
—
—
—
0
0
12
121
0.99
0.00
1.7
2.7
0.2
0.2
e9/l
0.21
12
101
12
121
0.99
0.00
1.3
1.3
6.3
6.3
ug/l
0.00
12
102
11
108
1.02
0.00
1.0
1.1
—
—
—
0
0
18
182
0.99
0.00
1.7
1.3
—
—
—
0
0
14
143
0.98
0.00
1.1
1.1
—
—
—
0
0
25
253
0.99
0.00
3.0
4.6
33.3
68.9
u/ml
—
9
73
45
447
1.01
0.00
7.3
6.6
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
64.5
—
0
8
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.2
—
252.8
—
0
6
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
2.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
0.00
4.3
6.5
9.7
11.0
mg/l
—
7
74
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
0.00
0.0
1.1
—
13.0
—
0
8
0
5
0.00
0.00
0.0
1.0
—
76.8
—
0
5
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
6
63
0.95
0.00
4.5
1.9
14.7
16.6
umol/l
—
6
63
0
8
0.00
0.00
0.0
1.3
—
28.3
—
0
8
6
59
1.02
0.00
1.0
1.7
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
0.00
0.0
4.0
—
—
—
0
0
18
180
1.00
0.00
1.0
1.0
—
0.2
—
0
23
5
51
0.98
0.00
1.0
1.1
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
10
100
1.00
0.00
2.4
2.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
2.4
—
0
8

Mortality – FinRegistry

Association

Association between endpoint O15_POLYHYDR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_POLYHYDR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: O15_POLYHYDR – Polyhydramnios

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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