No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1908 |
4. Check minimum number of eventsNone |
1908 |
5. Include endpointsNone |
1908 |
6. Filter based on genotype QC (FinnGen only) |
1908 |
Control definitions (FinnGen only)
- Control exclude
- O15_MATERN_CARE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O30-O48
- Name in latin
- Hydramnion
Similar endpoints
↥List of similar endpoints to
Polyhydramnios
based on the number of shared cases.
Similar with more cases:
- Maternal care related to the fetus and amniotic cavity and possible delivery problems
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 12633 | 12633 | - |
| Only index persons | 12478 | 12478 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.36 | 0.36 | - |
| Only index persons | 0.46 | 0.46 | - |
| Median age at first event (years) | |||
| Whole population | - | 31.06 | - |
| Only index persons | - | 31.05 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1908 | 1908 | - |
| Unadjusted period prevalence (%) | 0.65 | 0.65 | - |
| Median age at first event (years) | 31.28 | 31.28 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1656
- Matched controls
- 16561
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
+∞
323.0
387
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
1322.6
323.0
474
5
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
16.1
323.0
637
617
O40
ICD-10 Finland
Polyhydramnios
+∞
323.0
1413
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
17.6
275.5
456
349
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
9.5
224.6
516
754
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
15.1
219.1
384
324
O82.0
ICD-10 Finland
Delivery by elective caesarean section
29.3
212.5
292
120
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
7.8
211.7
561
1019
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
5.7
200.2
744
2087
O32.1
ICD-10 Finland
Maternal care for breech presentation
314.3
194.6
194
7
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
7.6
187.4
499
891
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4.0
153.2
953
4164
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
1541.5
146.1
140
*
MAA00
NOMESCO Finland
Amniocentesis
29.6
145.8
199
76
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
+∞
140.7
133
*
6570A
ICD-9 Finland
Polyhydramnios[POLYHYDRAMNION, RASKAUDEN AIKANA]
+∞
135.3
128
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
4.1
135.1
705
2550
Z39.2
ICD-10 Finland
Routine postpartum follow-up
4.3
132.3
623
2041
SPAT1379
SPAT
Health check-up of pregnant person
4.5
127.0
544
1615
SPAT1197
SPAT
Extensive health check-up of expecting family
4.1
123.9
608
2045
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
184.6
116.0
120
7
SPAT1380
SPAT
Postpartum check-up
4.5
112.4
466
1315
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
18.8
112.0
176
104
O48
ICD-10 Finland
Prolonged pregnancy
1050.8
102.3
99
*
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
3.6
101.3
596
2257
SPAT1196
SPAT
Monitoring of normal pregnancy
4.8
96.2
365
924
W84
ICPC
Pregnancy high risk
8.3
96.1
226
309
W78
ICPC
Pregnancy
3.4
96.1
624
2531
ZXD05
NOMESCO Finland
Urgent procedure
3.1
92.1
699
3149
63440
ICD-8 Finland
Other complications of pregnancy, Premature rupture of membrane without delivery
+∞
90.4
86
*
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
+∞
84.1
80
*
XMA22
NOMESCO Finland
General examination of pregnant woman
5.0
82.2
290
670
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
+∞
82.0
78
*
O80.8
ICD-10 Finland
Other single spontaneous delivery
6.9
79.7
213
349
Z32.1
ICD-10 Finland
Pregnancy confirmed
3.5
76.1
428
1509
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.0
75.8
224
418
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
75.6
72
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
3.3
74.0
459
1736
O99.80
ICD-10 Finland
The fear of childbirth
5.2
72.9
244
528
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
+∞
70.3
67
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
4.3
69.1
282
748
MAC96
NOMESCO Finland
Other induction or advancement of labour
8.0
66.4
157
213
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
4.9
66.0
237
551
O60
ICD-10 Finland
Preterm labour and delivery
12.0
64.9
122
109
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
+∞
61.9
59
*
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
609.5
60.1
59
*
O30.0
ICD-10 Finland
Twin pregnancy
+∞
59.7
57
*
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
3.0
58.7
418
1699
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
307.8
58.7
59
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
10.9
57.6
113
110
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
3.0
52.7
351
1355
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
5.9
51.9
152
277
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
5.0
51.3
177
390
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
9.3
51.1
109
124
MAB10
NOMESCO Finland
External version
111.6
50.1
54
5
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
7.7
49.7
120
167
O61.0
ICD-10 Finland
Failed medical induction of labour
19.4
49.6
76
41
SPAT1357
SPAT
Monitoring of problem during pregnancy
5.6
47.9
148
287
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
7.7
47.8
115
159
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
3.4
47.2
255
843
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
4.1
46.7
196
524
SPAT1262
SPAT
Handing over of treatment supplies
3.2
45.1
260
899
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.7
44.7
162
375
SPAT1189
SPAT
Other ultrasound examination during pregnancy
5.0
44.2
151
328
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
3.9
44.0
197
557
WX320
NOMESCO Finland
Spinalanesthesy
2.8
44.0
334
1387
W85
ICPC
Gestational diabetes
4.2
43.5
179
469
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.0
41.7
845
5603
6570B
ICD-9 Finland
Polyhydramnios[POLYHYDRAMNION, SYNNYTYKSEN AIKANA]
+∞
40.8
39
*
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.3
40.6
129
258
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.0
40.4
262
977
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
6.9
39.6
102
156
O47.9
ICD-10 Finland
False labour, unspecified
14.5
39.4
67
48
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.6
37.5
303
1294
O20.0
ICD-10 Finland
Threatened abortion
5.8
37.2
109
198
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
7.3
37.1
91
130
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
4.8
36.5
127
281
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
7.6
36.3
87
120
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
7.3
36.1
89
128
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
5.1
35.9
117
241
O41.0
ICD-10 Finland
Oligohydramnios
+∞
35.5
34
*
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
4.9
35.4
120
258
A10AE04
ATC
insulin glargine; parenteral
3.8
35.0
160
458
SPAT1249
SPAT
Treatment-related counselling outside office
1.9
34.4
717
4684
SPAT1263
SPAT
Sampling
1.9
33.8
736
4875
W92
ICPC
Compl labour/ delivery livebirth
7.1
33.8
85
126
WX234
NOMESCO Finland
Paracervical blockade
4.1
33.5
138
360
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
6.2
32.8
91
154
A10AA01
ATC
NA
5.1
32.8
108
225
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.1
32.8
430
2323
O02.1
ICD-10 Finland
Missed abortion
3.1
32.6
199
709
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
3.4
32.3
171
550
A10AA02
ATC
NA
5.0
32.3
108
229
O32.0
ICD-10 Finland
Maternal care for unstable lie
323.0
32.0
32
*
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
323.0
32.0
32
*
A10AE05
ATC
insulin detemir; parenteral
4.2
31.6
125
314
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
30.3
29
*
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
+∞
30.3
29
*
O36.3
ICD-10 Finland
Maternal care for signs of fetal hypoxia
+∞
30.3
29
*
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
5.7
29.6
87
159
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
+∞
29.2
28
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
5.1
28.9
94
193
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
13.5
28.8
50
38
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
7.8
28.7
67
89
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
17.1
28.5
45
27
O81.4
ICD-10 Finland
Vacuum extractor delivery
2.7
28.3
216
881
O36.4
ICD-10 Finland
Maternal care for intrauterine death
+∞
28.2
27
*
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
5.7
28.0
82
149
H04AA01
ATC
glucagon; nasal, parenteral
4.7
27.2
96
216
8811
FHL
Cesarean section
3.5
26.6
128
382
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
46.5
26.5
32
7
103
Kela drug reimbursment
Diabetes, insulin-treated
2.4
26.5
257
1193
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.4
26.1
254
1178
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
+∞
26.1
25
*
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.2
25.8
289
1437
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
9.6
25.8
53
57
SPAT1301
SPAT
No procedures
1.9
25.7
478
2915
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
13.7
25.5
44
33
W90
ICPC
Uncompl labour/delivery livebirth
2.9
24.8
158
576
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
5.5
24.5
74
140
T89
ICPC
Diabetes insulin dependent
3.8
24.1
107
298
MAE00
NOMESCO Finland
Outlet vacuum delivery
2.6
23.8
183
747
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
8.3
23.7
53
66
Z36.8
ICD-10 Finland
Other antenatal screening
4.3
23.2
88
213
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
4.7
23.1
80
177
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
2.8
22.4
150
562
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
12.9
22.2
39
31
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
+∞
21.9
21
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
21.8
654
4599
Z3232
NOMESCO Finland
Midwife
2.0
21.8
306
1665
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.7
21.2
95
267
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
9.2
21.1
44
49
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
3.2
21.1
113
366
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.0
21.0
130
464
MAA96
NOMESCO Finland
Other intrauterine operation on pregnant uterus or fetus
28.4
21.0
28
10
A10AE06
ATC
insulin degludec; parenteral
4.3
20.9
79
191
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
7.8
20.9
48
63
MAB20
NOMESCO Finland
Failed external version
111.4
20.6
22
*
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
7.8
20.4
47
62
Z39.1
ICD-10 Finland
Care and examination of lactating mother
4.2
20.4
78
191
W29
ICPC
Pregnancy symptom/complaint other
3.6
19.8
92
267
B01AB05
ATC
enoxaparin; parenteral
1.8
19.5
363
2184
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
4.5
19.4
69
157
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
+∞
18.8
18
*
MAX99
NOMESCO Finland
Assistance to normal delivery
1.9
18.5
300
1715
Z30.2
ICD-10 Finland
Sterilization
2.0
18.3
240
1265
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
3.2
18.1
98
320
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
5.7
17.9
51
91
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
3.1
17.9
103
352
O35.0
ICD-10 Finland
Maternal care for (suspected) central nervous system malformation in fetus
+∞
17.7
17
*
J01DB01
ATC
cefalexin; oral
1.7
17.7
1340
11774
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
7.6
17.7
41
55
SAA01
NOMESCO Finland
Simple examination of mouth
1.6
17.3
1238
10657
E66.01
ICD-10 Finland
Obesity due to excess calories
2.2
17.3
190
927
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.3
17.2
90
287
SPAT1312
SPAT
General health counselling
1.6
17.1
523
3632
SPAT1307
SPAT
Psychosocial counselling and guidance
2.3
17.1
169
786
MA4AT
NOMESCO Finland
Chorion biopsy with ultrasound guidance
50.5
17.0
20
*
O35.2
ICD-10 Finland
Maternal care for (suspected) hereditary disease in fetus
+∞
16.7
16
*
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
6.3
16.3
43
70
H3600, E103
ICD-10 Finland
NA
5.6
16.2
47
86
WX290
NOMESCO Finland
Other blockade of nerve
1.5
16.2
867
6892
SPAT1324
SPAT
Screening procedure
1.6
16.1
535
3789
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
11.8
16.1
29
25
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
3.7
16.1
71
199
6480A
ICD-9 Finland
Other current conditions in the mother classifiable elsewhere but complicating pregnancy, childbirth and the puerperium, Diabetes mellitus
9.1
15.9
33
37
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
9.6
15.9
32
34
G02CB01
ATC
bromocriptine; systemic
3.9
15.8
65
171
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
6.3
15.7
41
66
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
15.3
229
1265
A10BA02
ATC
metformin; oral
1.9
15.2
232
1292
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.4
15.2
134
589
SPAT1315
SPAT
Periodic health check-up of children and adolescents
2.7
15.0
108
424
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.5
15.0
701
5366
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
5.5
15.0
44
82
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
14.9
998
8273
SGA01
NOMESCO Finland
Tooth opening as first aid
1.8
14.8
312
1934
K02.1
ICD-10 Finland
Caries of dentine
1.5
14.7
1005
8362
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
14.6
484
3404
O45.9
ICD-10 Finland
Premature separation of placenta, unspecified
+∞
14.6
14
*
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
+∞
14.6
14
*
O34.0
ICD-10 Finland
Maternal care for congenital malformation of uterus
+∞
14.6
14
*
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
14.6
14
*
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
4.8
14.6
48
102
J01DA01
ATC
[U] cefalexin; systemic
1.5
14.5
1001
8333
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
151.3
14.5
15
*
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
1.8
14.4
288
1759
SPAT1192
SPAT
Gynaecological examination
1.7
14.3
325
2059
SPAT1310
SPAT
Counselling related to known health issue
1.6
14.1
459
3210
SPAT1240
SPAT
Therapeutic discussion
1.8
14.1
251
1471
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
8.2
13.8
30
37
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
4.8
13.7
45
96
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
8.0
13.6
30
38
MAA06
NOMESCO Finland
Amnioreduction
+∞
13.6
13
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.7
13.4
278
1714
R51.80
ICD-10 Finland
Headache
1.7
13.3
286
1782
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.0
13.3
189
1024
SPAT1303
SPAT
Counselling and guidance related to growth and development
6.5
12.9
33
52
SPAT1373
SPAT
Combined screening in early pregnancy
4.0
12.9
51
131
ZXE00
NOMESCO Finland
One hour or less
1.5
12.9
595
4499
N02BE01
ATC
paracetamol; systemic, rectal
1.6
12.8
1318
11804
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
12.6
434
3065
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
4.3
12.6
46
110
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
+∞
12.5
12
*
O30.00
ICD-10 Finland
Twin pregnancy with separate amniotic and chorionic sacs
+∞
12.5
12
*
O61.1
ICD-10 Finland
Failed instrumental induction of labour
20.2
12.5
18
9
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
131.0
12.4
13
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.7
12.4
85
325
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
3.8
12.4
52
141
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
3.5
12.3
57
168
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.8
12.3
210
1214
SPAT1153
SPAT
Removal of sutures
1.6
12.2
347
2330
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.8
12.2
206
1183
SPAT1283
SPAT
Restricted health certificate
1.5
12.0
465
3367
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.9
11.9
38
79
SPAT1391
SPAT
Counselling and guidance related to family situation
4.4
11.9
42
97
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
11.8
886
7349
W30
ICPC
Pregnancy, Medical examin/health eval complete
6.2
11.8
31
51
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
4.1
11.8
45
112
177
Kela drug reimbursment
Insulin glargine 300 U / ml
4.2
11.6
43
104
E66.9
ICD-10 Finland
Obesity, unspecified
2.8
11.6
76
282
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
8.2
11.6
25
31
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
3.2
11.5
60
193
MA2BG
NOMESCO Finland
Fetal examination with high intensity magnet
+∞
11.5
11
*
6510B
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, SYNNYTYKSEN AIKANA]
+∞
11.5
11
*
6510A
ICD-9 Finland
Multiple gestation, Twin pregnancy[GEMINI, RASKAUDEN AIKANA]
+∞
11.5
11
*
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
3.4
11.4
55
167
O33.9
ICD-10 Finland
Maternal care for disproportion, unspecified
120.8
11.4
12
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
3.5
11.3
51
147
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.6
11.3
388
2728
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
7.1
11.0
26
37
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
5.6
11.0
31
56
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.2
10.9
115
549
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.8
10.8
193
1131
SPAT1383
SPAT
Extensive health check-up at 4 years of age
4.9
10.7
34
71
P01AB01
ATC
metronidazole; oral, rectal
1.4
10.6
659
5231
XMA20
NOMESCO Finland
Early examination of pregnancy
3.6
10.6
46
129
O14.1
ICD-10 Finland
Severe pre-eclampsia
5.3
10.6
31
59
A02BC01
ATC
omeprazole; systemic
1.6
10.5
323
2206
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
5.7
10.4
29
52
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
4.9
10.2
32
66
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.0
10.2
130
675
Z36.2
ICD-10 Finland
Other antenatal screening based on amniocentesis
13.2
10.2
17
13
SPAT1393
SPAT
Guidance to support interaction between parent and child
7.7
9.9
22
29
ZXD00
NOMESCO Finland
Emergency procedure
3.0
9.9
57
197
W18
ICPC
Post-partum symptom/complaint other
6.3
9.9
25
40
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
5.5
9.8
28
52
O23.1
ICD-10 Finland
Infections of bladder in pregnancy
9.6
9.8
19
20
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
3.6
9.8
43
123
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
9.7
497
3788
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
4.5
9.6
33
75
XCK10
NOMESCO Finland
Photography of fundus of eye
2.2
9.5
101
485
O12.1
ICD-10 Finland
Gestational proteinuria
5.5
9.5
27
50
MA3AE
NOMESCO Finland
Combined first trimester screening
2.1
9.5
114
576
O46.8
ICD-10 Finland
Other antepartum haemorrhage
+∞
9.4
9
*
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
4.1
9.4
35
87
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
9.2
877
7454
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
3.6
9.1
39
109
W31
ICPC
Pregnancy, Medical examin/health eval partial
3.1
9.1
48
158
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
36.9
9.0
11
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.6
9.0
62
241
W27
ICPC
Fear of complications of pregnancy
4.1
9.0
33
81
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
6.5
9.0
22
34
MBA20
NOMESCO Finland
Expression of placenta
5.8
8.9
24
42
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
5.0
8.8
27
55
Z31.5
ICD-10 Finland
Genetic counselling
2.0
8.8
105
533
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
5.1
8.6
26
52
H36.00
ICD-10 Finland
Diabetic background retinopathy
4.3
8.6
30
70
A10BK01
ATC
dapagliflozin; oral
3.2
8.6
44
142
G03GA01
ATC
chorionic gonadotrophin; parenteral
1.9
8.6
116
617
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.6
8.6
59
230
MAG00
NOMESCO Finland
Assisted breech delivery
16.4
8.6
13
8
SPAT1273
SPAT
Structured assessment of psychoactive substance / tobacco use
2.2
8.5
82
378
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
8.5
315
2235
SPAT1260
SPAT
Consultation of another employee
1.6
8.5
225
1475
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
8.5
786
6612
H01
ICPC
Ear pain/earache
1.7
8.5
188
1175
SPAT1316
SPAT
Extensive health check-up of children and adolescents
2.3
8.4
73
321
O42.2
ICD-10 Finland
Premature rupture of membranes, labour delayed by therapy
+∞
8.3
8
*
O41.9
ICD-10 Finland
Disorder of amniotic fluid and membranes, unspecified
+∞
8.3
8
*
O33.2
ICD-10 Finland
Maternal care for disproportion due to inlet contraction of pelvis
+∞
8.3
8
*
6450B
ICD-9 Finland
Prolonged pregnancy[GRAVIDITAS PROLANGATA CUM PARTU]
+∞
8.3
8
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.2
8.3
79
364
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
4.6
8.3
27
59
B02AA02
ATC
tranexamic acid; systemic
1.5
8.3
291
2040
MAA10
NOMESCO Finland
Biopsy of chorionic villus
10.8
8.3
15
14
Z29
ICPC
Social problem NOS
3.7
8.2
34
93
C08CA05
ATC
nifedipine; systemic
2.5
8.2
61
248
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
8.2
96
481
WX110
NOMESCO Finland
Local anesthesy
1.4
8.2
1121
10013
SPAT1370
SPAT
Other health check-up
2.6
8.1
59
236
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
4.1
8.1
30
75
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.8
8.0
136
785
G03GB02
ATC
clomifene; oral
2.7
8.0
53
203
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
4.1
8.0
29
71
OAA12
SPAT
NA
2.8
7.9
47
168
Z11.3
ICD-10 Finland
Special screening examination for infections with a predominantly sexual mode of transmission
0.5
7.9
52
1061
H3603, E103
ICD-10 Finland
NA
3.6
7.9
34
97
O72.0
ICD-10 Finland
Third-stage haemorrhage
2.5
7.9
58
235
EBA00
NOMESCO Finland
Extraction of tooth
1.4
7.9
463
3596
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.9
7.9
30
77
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.7
1120
10039
K04.0
ICD-10 Finland
Pulpitis
1.6
7.6
187
1201
O64.4
ICD-10 Finland
Obstructed labour due to shoulder presentation
25.1
7.6
10
*
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
8.9
7.5
15
17
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.7
7.5
155
950
SPAT1193
SPAT
Pap smear
1.5
7.5
279
1981
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.6
7.4
173
1098
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
3.5
7.4
32
92
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
2.3
7.3
63
276
O32.8
ICD-10 Finland
Maternal care for other malpresentation of fetus
+∞
7.3
7
*
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
+∞
7.3
7
*
6584B
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Infection of amniotic cavity[AMNIONITIS, SYNNYTYKSEN AIKANA]
+∞
7.3
7
*
O36.2
ICD-10 Finland
Maternal care for hydrops fetalis
+∞
7.3
7
*
O33.3
ICD-10 Finland
Maternal care for disproportion due to outlet contraction of pelvis
+∞
7.3
7
*
Z37.0
ICD-10 Finland
Single live birth
1.5
7.2
257
1804
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
6.3
7.2
18
29
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
7.2
173
1105
H3601, E103
ICD-10 Finland
NA
4.3
7.2
25
59
O47
ICD-10 Finland
False labour
4.6
7.2
23
50
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
3.8
7.2
28
74
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.5
7.1
236
1631
C07AG01
ATC
labetalol; systemic
3.3
7.1
34
106
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
3.3
7.1
34
106
SPAT1195
SPAT
Antenatal classes
2.1
7.1
79
390
M54.5
ICD-10 Finland
Low back pain
1.4
7.1
502
4012
SPAT1028
SPAT
Ultrasound examination of paranasal sinuses
1.9
7.0
103
565
HMAK
NOMESCO Finland
NA
1.5
7.0
215
1462
E10
ICD-10 Finland
Type 1 diabetes mellitus
2.8
7.0
42
153
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
6.3
6.9
17
27
H43.1
ICD-10 Finland
Vitreous haemorrhage
3.3
6.9
32
98
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.3
6.8
539
4378
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.6
6.8
185
1223
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
6.1
6.8
17
28
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
5.7
6.8
18
32
SPAT1389
SPAT
Visit based on need for special support
2.4
6.7
55
238
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
6.7
620
5151
SPAT1305
SPAT
Counselling and guidance related to physical exercise
1.8
6.7
110
627
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
2.9
6.7
37
128
WX600
NOMESCO Finland
Single shot through catheter
2.8
6.6
40
146
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.8
6.6
104
586
O62.0
ICD-10 Finland
Primary inadequate contractions
6.5
6.6
16
25
N05AH02
ATC
clozapine; systemic
0.1
6.6
*
222
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.6
6.6
46
181
SPAT1382
SPAT
Extensive health check-up at 18 months of age
4.4
6.5
22
51
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
6.5
129
781
SPAT1097
SPAT
Recording of ECG
1.7
6.5
117
691
CKC15
NOMESCO Finland
Panretinal photocoagulation
5.3
6.5
18
34
Z37.1
ICD-10 Finland
Single stillbirth
70.1
6.4
7
*
CKC12
NOMESCO Finland
Photocoagulation of retina
2.4
6.4
49
204
Z22
ICPC
Illness problem parent/family memb
6.6
6.3
15
23
Z82.7
ICD-10 Finland
Family history of congenital malformations, deformations and chromosomal abnormalities
6.6
6.3
15
23
W05
ICPC
Pregnancy vomiting/nausea
3.5
6.3
27
78
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
2.6
6.3
43
170
25009
ICD-8 Finland
Diabetes mellitus, Unspecified
11.1
6.3
11
10
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
4.6
6.3
20
44
O43.0
ICD-10 Finland
Placental transfusion syndromes
+∞
6.3
6
*
O35.5
ICD-10 Finland
Maternal care for (suspected) damage to fetus by drugs
+∞
6.3
6
*
6412B
ICD-9 Finland
Antepartum haemorrhage, abruptio placentae and placenta praevia, Premature separation of placenta[ABLATIO PLACENTAE ANTETEMPUS,SYNN PÄÄTT HOITOJAKSO]
+∞
6.3
6
*
N61
ICD-10 Finland
Inflammatory disorders of breast
2.1
6.2
66
320
MAC98
NOMESCO Finland
Other induction of labor
26.8
6.2
8
*
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
4.8
6.2
19
40
SFA00
NOMESCO Finland
Small filling
1.5
6.2
182
1223
WX720
NOMESCO Finland
Own respiration
2.5
6.2
45
183
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
6.2
431
3421
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
7.0
6.2
14
20
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.4
6.2
337
2567
A05AA02
ATC
ursodeoxycholic acid; oral
3.0
6.2
32
107
SGB30
NOMESCO Finland
Other demanding filling of root channel of tooth
1.5
6.2
214
1497
G03DB01
ATC
dydrogesterone; oral
1.4
6.1
291
2162
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.5
6.1
179
1201
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
8.6
6.1
12
14
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
4.4
6.0
20
46
O21
ICD-10 Finland
Excessive vomiting in pregnancy
4.2
6.0
21
51
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.2
6.0
21
51
Mortality – FinRegistry
↥Association
Association between endpoint O15_POLYHYDR and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have O15_POLYHYDR.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: O15_POLYHYDR – Polyhydramnios
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data