Vestibular neuronitis

H8_VESTIBNEUR

vestibular neuronitis: Idiopathic inflammation of the vestibular nerve, characterized clinically by the acute or subacute onset of vertigo; nausea; and imbalance. The cochlear nerve is typically spared and hearing loss and tinnitus do not usually occur. Symptoms usually resolve over a period of days to weeks. (Adams et al., Principles of Neurology, 6th ed, p304)

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H81.2
  • Hospital discharge: ICD-9 3861
  • Cause of death: ICD-10 H81.2
  • Cause of death: ICD-9 3861

2 out of 7 registries used, show all original rules.

3442

4. Check minimum number of events

None

3442

5. Include endpoints

None

3442

6. Filter based on genotype QC (FinnGen only)

3442

Control definitions (FinnGen only)

Control exclude
H8_INNER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
H81
Name in latin
Neuronitis vestibularis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 24109 13022 10994
Only index persons 22996 12504 10492
Unadjusted period prevalence (%)
Whole population 0.34 0.37 0.31
Only index persons 0.43 0.46 0.40
Median age at first event (years)
Whole population 55.00 55.56 54.40
Only index persons 54.48 54.96 53.91

-FinnGen-

Key figures

All Female Male
Number of individuals 3442 1939 1503
Unadjusted period prevalence (%) 0.66 0.66 0.66
Median age at first event (years) 55.08 53.73 56.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3053
Matched controls
30528
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R42
ICD-10 Finland
Dizziness and giddiness
11.1
323.0
1796
3491
H81.2
ICD-10 Finland
Vestibular neuronitis
15231.4
323.0
2769
17
3861A
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other and unspecified peripheral vertigo
+∞
317.3
299
*
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
10.8
312.2
646
741
H81.3
ICD-10 Finland
Other peripheral vertigo
56.4
302.0
359
72
AA1AD
NOMESCO Finland
CT of head and brain
3.2
152.0
1059
4397
DFF59
NOMESCO Finland
Other assessment of balance
46.2
145.3
179
41
H81.0
ICD-10 Finland
Ménière disease
57.9
126.0
149
27
N07CA01
ATC
betahistine; oral
5.3
118.9
395
834
DFF00
NOMESCO Finland
Pure tone audiometry
4.0
103.3
454
1264
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.9
78.2
552
2168
N17
ICPC
Vertigo/dizziness
3.2
78.1
458
1587
H81.9
ICD-10 Finland
Disorder of vestibular function, unspecified
32.9
77.3
102
32
H02AB04
ATC
methylprednisolone; systemic
2.5
63.7
583
2636
DFF40
NOMESCO Finland
Otoneurologic examination of vertigo
59.9
45.4
53
9
H02AB06
ATC
prednisolone; systemic
1.7
38.3
1416
10471
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.6
35.7
288
1193
DFF50
NOMESCO Finland
Electronystagmography
91.1
32.8
36
*
UDC00
NOMESCO Finland
Ear microscopy
2.6
32.6
250
1005
A03FA01
ATC
metoclopramide; systemic, rectal
1.8
29.9
631
3900
H81.4
ICD-10 Finland
Vertigo of central origin
16.4
29.3
47
29
N05AB04
ATC
prochlorperazine; systemic, rectal
4.4
27.3
102
240
A02BC02
ATC
pantoprazole; systemic
1.5
26.2
1887
15772
7804A
ICD-9 Finland
General symptoms, Dizziness and giddiness
5.9
25.4
72
125
R51.80
ICD-10 Finland
Headache
1.9
25.0
401
2245
H91.2
ICD-10 Finland
Sudden idiopathic hearing loss
4.1
24.1
96
240
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.5
23.6
1242
9612
H90.4
ICD-10 Finland
Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side
3.1
22.8
130
433
DE2CG
NOMESCO Finland
Acoustic channel extensive MRI examination with high intensity magnet
5.5
20.5
61
113
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.1
19.9
230
1131
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
19.4
1647
13803
R11
ICD-10 Finland
Nausea and vomiting
2.1
19.4
221
1076
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.9
18.8
277
1500
H55
ICD-10 Finland
Nystagmus and other irregular eye movements
16.3
18.3
29
18
G44.2
ICD-10 Finland
Tension-type headache
1.8
17.9
357
2140
M79.6
ICD-10 Finland
Pain in limb
1.4
17.4
956
7338
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
3.3
16.9
86
266
H80.0
ICD-10 Finland
Otosclerosis involving oval window, nonobliterative
+∞
16.7
16
*
H81.8
ICD-10 Finland
Other disorders of vestibular function
40.3
16.3
20
5
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
16.0
731
5390
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.6
14.9
422
2784
N02BE01
ATC
paracetamol; systemic, rectal
1.4
14.3
2467
22748
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
14.2
527
3706
M03BX02
ATC
tizanidine; oral
1.3
14.1
1684
14589
PA7BD
NOMESCO Finland
CT angiography of neck and brain
3.7
13.9
60
164
DE2BG
NOMESCO Finland
Acoustic channel MRI examination with high intensity magnet
4.7
13.8
46
99
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
13.4
400
2668
SPAT1310
SPAT
Counselling related to known health issue
1.4
13.0
840
6565
R05
ICPC
Cough
1.5
12.9
560
4069
SPAT1153
SPAT
Removal of sutures
1.4
12.7
858
6751
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
2.2
12.7
124
567
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.1
12.7
67
216
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
12.7
898
7126
TDW99
NOMESCO Finland
Other minor procedure in surgery of ear, nose and larynx
2.5
12.5
98
402
J01FA10
ATC
azithromycin; systemic
1.3
12.5
1498
12880
G43.9
ICD-10 Finland
Migraine, unspecified
2.2
12.3
127
597
C08CA01
ATC
amlodipine; oral
1.4
12.2
960
7732
J01DB01
ATC
cefalexin; oral
1.4
12.1
2291
21019
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.4
12.0
616
4610
H82
ICPC
Vertiginous syndrome
3.5
11.9
54
156
SPAT1263
SPAT
Sampling
1.3
11.7
1116
9251
L03
ICPC
Low back symptom/complaint
1.4
11.7
597
4463
H80.9
ICD-10 Finland
Otosclerosis, unspecified
30.1
11.6
15
5
C09CA01
ATC
losartan; oral
1.4
11.6
628
4746
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
11.5
209
1212
C08CA13
ATC
lercanidipine; oral
1.5
11.3
349
2349
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
11.3
301
1954
C10AA05
ATC
atorvastatin; oral
1.3
11.1
1013
8320
R53
ICD-10 Finland
Malaise and fatigue
1.4
11.1
497
3618
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
10.9
544
4044
SPAT1043
SPAT
Audiometry
1.6
10.7
266
1691
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
10.5
545
4076
SPAT1097
SPAT
Recording of ECG
1.5
10.4
383
2674
M01AH05
ATC
etoricoxib; oral
1.3
10.4
1573
13812
R06.0
ICD-10 Finland
Dyspnoea
1.4
10.4
618
4735
R01AD09
ATC
mometasone; nasal
1.3
10.3
1140
9597
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
10.1
1864
16765
J01AA02
ATC
doxycycline; systemic
1.3
10.1
2187
20104
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.3
10.1
748
5941
UJF32
NOMESCO Finland
Coloscopy
1.4
10.0
669
5221
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
9.9
1211
10322
M01AE01
ATC
ibuprofen; systemic, rectal
1.4
9.8
2550
24023
A98
ICPC
Health maint/preventive medicine
1.5
9.6
2832
27238
J01FA09
ATC
clarithromycin; systemic
1.3
9.6
807
6521
A02BC05
ATC
esomeprazole; systemic
1.3
9.6
1070
8994
L08
ICPC
Shoulder symptom/complaint
1.4
9.6
470
3478
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.5
9.4
376
2671
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
2.5
9.4
72
295
M54.5
ICD-10 Finland
Low back pain
1.3
9.3
805
6523
A02BC01
ATC
omeprazole; systemic
1.3
9.2
703
5597
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
9.2
977
8154
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
9.1
733
5880
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.4
9.1
392
2831
TAB00
NOMESCO Finland
Lumbar puncture
2.0
9.0
114
585
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
9.0
1100
9336
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
8.9
374
2684
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.8
542
4172
M25.5
ICD-10 Finland
Pain in joint
1.3
8.7
697
5582
P01AB01
ATC
metronidazole; oral, rectal
1.3
8.7
998
8399
S82
ICPC
Naevus/mole
1.5
8.6
289
1979
M79.1
ICD-10 Finland
Myalgia
1.5
8.6
303
2101
R75
ICPC
Sinusitis acute/chronic
2.0
8.5
106
541
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.4
8.5
387
2823
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
1.8
8.5
143
817
H93.1
ICD-10 Finland
Tinnitus
1.7
8.4
157
923
SPAT1312
SPAT
General health counselling
1.3
8.4
787
6434
A05
ICPC
Feeling ill
1.9
8.4
116
618
H21.2
ICD-10 Finland
Degeneration of iris and ciliary body
+∞
8.3
8
*
A02BC03
ATC
lansoprazole; oral
1.3
8.3
732
5938
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
8.3
189
1181
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
4.8
8.2
26
55
R74
ICPC
Upper respiratory infection acute
1.3
8.2
614
4862
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
8.1
391
2878
DFF15
NOMESCO Finland
Speech audiometry
2.0
8.1
105
547
J01MA02
ATC
ciprofloxacin; systemic
1.3
8.0
996
8440
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.3
8.0
1131
9733
R03AC02
ATC
salbutamol; inhalant
1.2
8.0
1341
11773
PA6AD
NOMESCO Finland
CT of neck arteries
3.3
8.0
38
116
C09CA06
ATC
candesartan; oral
1.3
8.0
540
4208
Z01.2
ICD-10 Finland
Dental examination
1.3
7.9
992
8413
C07AB07
ATC
bisoprolol; oral
1.2
7.9
1215
10562
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
4.9
7.9
24
49
H83.0
ICD-10 Finland
Labyrinthitis
45.1
7.7
9
*
Z00.0
ICD-10 Finland
General medical examination
1.4
7.7
437
3313
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
7.7
1208
10517
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
1.6
7.7
181
1140
A04AA01
ATC
ondansetron; systemic, rectal
1.7
7.6
163
1000
N02AX02
ATC
tramadol; systemic, rectal
1.2
7.6
1102
9501
M01AX17
ATC
nimesulide; oral
1.3
7.6
621
4979
M01AB05
ATC
diclofenac; systemic, rectal
1.2
7.5
1794
16345
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.4
7.5
426
3229
H53.1
ICD-10 Finland
Subjective visual disturbances
1.7
7.4
144
857
H43.8
ICD-10 Finland
Other disorders of vitreous body
1.6
7.4
211
1393
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
1.8
7.4
128
738
A11
ICPC
Chest pain NOS
1.6
7.4
172
1080
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
3.1
7.4
38
124
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
7.4
1463
13047
L01
ICPC
Neck symptom/complaint
1.4
7.4
310
2226
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.3
7.3
540
4260
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.3
988
8438
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
7.3
491
3823
N03AX12
ATC
gabapentin; oral
1.4
7.2
376
2806
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
2.5
7.2
52
209
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.2
7.2
1022
8775
J02AC01
ATC
fluconazole; systemic
1.3
7.2
955
8138
XF400
NOMESCO Finland
ECG with 12 standard connections
1.4
7.1
399
3018
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
7.1
272
1918
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
2.4
7.1
54
224
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.3
7.0
489
3822
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.1
6.8
70
333
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.7
557
4471
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.6
769
6442
R03DC03
ATC
montelukast; oral
1.4
6.6
368
2777
N01
ICPC
Headache
1.5
6.6
191
1268
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.3
6.6
509
4041
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
6.5
1617
14677
DDA00
NOMESCO Finland
Stapedotomy
70.0
6.4
7
*
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.6
6.4
179
1179
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
1.8
6.4
103
584
G04CA01
ATC
alfuzosin; oral
1.4
6.4
271
1950
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
1.8
6.4
95
524
L15
ICPC
Knee symptom/complaint
1.3
6.3
498
3963
R20.2
ICD-10 Finland
Paraesthesia of skin
1.6
6.3
143
892
3868X
ICD-9 Finland
Vertiginous syndromes and other disorders of vestibular system, Other disorders of labyrinth
+∞
6.2
6
*
H80.8
ICD-10 Finland
Other otosclerosis
+∞
6.2
6
*
M01AX05
ATC
glucosamine; oral
1.3
6.2
497
3965
M01AE02
ATC
naproxen; oral, rectal
1.2
6.2
1429
12854
N02AJ06
ATC
codeine and paracetamol; systemic
1.2
6.2
936
8064
R01AD12
ATC
fluticasone furoate; nasal
1.3
6.1
680
5657
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.4
6.1
338
2549
G04BD12
ATC
mirabegron; oral
1.4
6.1
236
1668
D82
ICPC
Teeth/gum disease
1.2
6.1
806
6840
S18
ICPC
Laceration/cut
1.2
6.1
1041
9083
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.3
6.1
552
4478
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.3
6.0
462
3662

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
1316
8763
1.81
57.93
2.1
2.2
152.6
221.2
u/l
2.61
1254
8215
1539
10990
1.72
51.30
3.7
3.6
34.8
100.1
ng/l
0.91
1079
7641
2142
17028
1.68
45.40
4.3
4.8
6.7
6.7
mmol/l
0.42
2028
15947
1543
11860
1.55
33.05
8.6
9.3
1.2
1.3
inr
1.64
462
3404
3226
29796
2.32
32.27
18.2
16.9
4.0
4.0
mmol/l
4.19
3160
29023
3217
29703
2.27
31.79
18.1
16.7
139.8
139.7
mmol/l
2.14
3161
28980
3123
28651
1.97
29.31
15.6
14.6
20.3
24.3
mg/l
10.74
2543
22778
679
4433
1.66
28.30
1.9
2.1
29.2
29.9
s
1.92
656
4303
3198
29822
2.02
24.95
15.5
13.6
—
—
—
0
0
2443
21355
1.50
24.26
4.5
4.1
11.2
12.5
mm/h
5.10
2248
19762
3249
30583
2.11
22.91
18.5
17.0
79.2
77.7
umol/l
1.74
3249
30572
2190
18847
1.45
22.67
5.1
4.5
1713.7
1836.2
e6/l
0.04
49
270
2264
19710
1.43
21.23
4.8
4.3
—
—
—
0
0
1163
9118
1.42
19.28
2.6
2.6
58.1
57.6
u/l
0.15
1067
8431
1733
14547
1.39
19.11
6.3
6.9
1.2
1.2
mmol/l
0.57
1433
12277
3324
31790
2.33
18.84
23.7
21.4
245.9
250.5
e9/l
3.95
3273
30979
3324
31801
2.32
18.63
23.5
21.3
30.3
30.3
pg
0.00
3295
31334
3324
31802
2.32
18.61
23.6
21.3
90.9
91.2
fl
2.41
3295
31338
3324
31805
2.32
18.56
23.7
21.4
4.5
4.5
e12/l
1.88
3264
30892
3324
31811
2.31
18.44
23.7
21.4
6.7
6.7
e9/l
0.51
3266
30892
3324
31815
2.31
18.37
23.8
21.5
136.1
135.3
g/l
2.90
3294
31355
3232
30630
1.90
18.28
11.5
10.6
27.9
26.3
u/l
0.82
3108
29569
2852
26237
1.51
17.76
5.2
4.8
1.9
2.0
mu/l
0.89
2600
23982
2452
21936
1.41
17.68
4.4
4.0
14.9
14.8
pmol/l
0.88
2207
19967
1581
13201
1.37
17.38
5.8
6.1
1.2
1.2
mmol/l
0.43
1431
11976
1078
8489
1.39
16.90
4.0
3.9
—
—
—
0
0
2884
26669
1.50
16.73
6.2
5.8
39.6
39.9
mmol/mol
1.17
2654
24656
2496
22510
1.40
16.31
7.8
7.7
76.7
78.5
u/l
1.18
2338
21243
1765
15247
1.32
14.32
6.1
6.3
11.1
11.5
umol/l
0.70
1657
14484
3080
29100
1.56
13.90
5.5
5.0
2.7
2.8
mmol/l
0.32
2834
26794
3013
28349
1.50
13.70
4.9
4.4
1.4
1.5
mmol/l
7.23
2765
26100
812
6283
1.38
13.62
1.8
1.7
1.0
1.2
mg/l
2.40
592
4836
302
1919
1.63
13.45
2.5
2.4
29.3
25.1
au/ml
—
6
105
279
1746
1.65
13.20
1.3
1.3
50.5
47.6
au/ml
0.08
11
77
2984
28092
1.47
12.81
5.2
4.6
6.0
6.0
mmol/l
0.04
2730
25630
3024
28553
1.49
12.68
4.9
4.5
4.6
4.7
mmol/l
1.14
2790
26442
2913
27389
1.41
11.76
4.4
4.0
1.4
1.3
mmol/l
3.73
2664
25047
1293
10900
1.30
11.72
3.8
3.4
—
5.8
—
0
8
209
1264
1.70
11.27
3.0
3.8
—
—
—
0
0
937
7603
1.32
11.13
4.6
4.1
0.0
0.0
estimate
0.05
308
2550
1609
14047
1.27
10.75
5.4
5.0
0.0
0.0
estimate
0.50
322
2663
268
1770
1.56
10.13
3.0
3.7
7.4
7.4
ph
0.26
32
237
766
6118
1.32
10.02
2.7
2.6
5.7
5.7
e6/l
0.02
673
5340
712
5630
1.33
9.98
3.9
3.6
395.0
403.4
ng/l
0.02
542
4441
1596
14019
1.26
9.78
4.1
3.7
0.0
0.0
estimate
0.00
315
2604
1616
14218
1.26
9.75
4.2
3.7
0.0
0.0
estimate
0.03
314
2561
268
1794
1.54
9.54
3.0
3.7
5.1
5.2
kpa
0.63
239
1673
2247
20589
1.26
9.33
4.0
3.8
—
—
—
0
0
497
3780
1.37
8.92
1.3
1.3
536.6
525.9
titre
0.04
101
817
51
203
2.54
8.71
1.1
1.1
222.0
294.8
mg/l
2.75
45
171
51
208
2.47
8.30
1.2
1.1
32.6
42.2
mg/l
1.60
41
168
1360
11884
1.24
8.25
2.3
2.2
78.0
78.2
nmol/l
0.12
1219
10681
998
8444
1.26
8.05
3.1
3.0
1303.3
1378.9
ng/l
0.16
862
7250
43
165
2.63
7.94
1.2
1.2
—
—
—
0
0
2058
18842
1.23
7.82
3.4
3.1
48.4
50.4
u/l
0.48
1906
17506
332
2416
1.41
7.74
3.5
3.5
—
—
—
0
0
170
1079
1.61
7.67
3.4
4.0
24.9
24.9
mmol/l
0.07
154
1005
344
2529
1.40
7.56
2.2
2.4
4.8
7.4
ug/l
3.03
303
2252
386
2915
1.37
7.21
4.7
4.4
—
—
—
0
0
1105
9550
1.23
7.18
5.1
4.9
2.5
2.8
ug/l
0.73
990
8577
1431
12706
1.22
7.11
4.7
4.9
36.2
35.4
g/l
7.72
1322
11828
302
2197
1.41
7.06
2.8
2.8
10.2
10.6
g/l
1.42
272
2008
742
6152
1.26
6.98
4.5
4.1
1.0
1.0
kg/l
1.01
97
903
108
627
1.75
6.87
1.1
1.2
3.7
3.8
mmol/l
0.95
103
590
1145
9976
1.22
6.79
3.1
3.4
2.4
2.4
mmol/l
0.61
980
8693
1636
14773
1.20
6.67
5.8
6.0
2.0
1.9
e9/l
0.29
1452
12981
1834
16749
1.20
6.59
8.3
9.2
4.0
4.1
e9/l
1.05
1633
14636
1601
14449
1.20
6.50
5.7
5.9
0.0
0.0
e9/l
1.25
1412
12474
1348
11974
1.21
6.48
3.0
2.8
136.3
132.5
ug/l
0.13
1230
11089
1522
13683
1.20
6.42
5.7
6.0
56.9
57.4
%
0.83
1412
12806
999
8636
1.22
6.31
3.3
3.2
—
—
—
0
0
901
7730
1.22
6.10
2.6
2.7
1798.4
5148.9
umol/l
3.72
774
6724
43
188
2.30
6.10
2.0
1.9
16.8
18.4
nmol/l
0.55
38
176
1121
9837
1.21
6.02
5.4
5.9
—
—
—
0
0
1537
13885
1.19
6.00
5.9
6.2
28.3
27.6
%
1.49
1417
12942
1000
8684
1.21
5.98
4.0
4.2
7.4
7.4
ph
0.56
209
1676
1158
10211
1.20
5.87
3.9
3.7
78.4
110.3
e6/l
0.60
860
7250
1642
14940
1.19
5.86
5.8
6.1
0.2
0.2
e9/l
0.52
1461
13094
1494
13486
1.19
5.83
5.8
6.1
2.9
2.9
%
0.04
1386
12579
104
627
1.68
5.83
1.2
1.3
10.1
25.4
e6/l
0.84
82
481
104
627
1.68
5.83
1.3
1.4
317.8
1519.6
e6/l
1.51
88
511
1585
14389
1.19
5.78
5.7
5.9
0.6
0.6
e9/l
0.54
1400
12421
436
3467
1.29
5.68
1.5
1.5
—
—
—
0
0
1319
11799
1.19
5.65
2.2
2.1
—
—
—
0
0
564
4633
1.26
5.65
1.3
1.2
12.2
11.6
u/ml
0.07
211
1784
1499
13561
1.19
5.64
6.1
6.4
8.6
8.7
%
0.84
1391
12707
592
4896
1.25
5.59
1.3
1.3
43.1
33.5
iu/ml
0.85
164
1537
849
7297
1.22
5.58
2.3
2.2
3.0
3.0
mg/l
0.14
714
6230
713
6039
1.23
5.39
1.3
1.2
2.1
1.7
u/ml
0.20
199
1579
1504
13647
1.18
5.38
4.1
4.1
—
—
—
0
0
104
646
1.63
5.23
1.4
1.3
11.1
10.6
u/l
0.12
79
523
16
44
3.65
5.20
1.3
1.0
—
—
—
0
0
32
133
2.42
5.12
7.6
13.2
—
—
—
0
0
92
558
1.67
5.09
1.2
1.3
—
—
—
0
0
911
7952
1.20
5.01
4.1
4.4
—
—
—
0
0
997
8776
1.19
4.99
3.4
3.2
46.8
73.2
e6/l
1.21
788
6752
1444
13115
1.17
4.98
5.9
6.1
0.7
0.7
%
0.24
1339
12236
784
6767
1.21
4.85
1.5
1.5
20.8
20.6
nmol/l
0.16
663
5771
334
2625
1.30
4.76
2.3
2.2
356.3
371.8
nmol/l
0.78
298
2420
405
3273
1.27
4.64
2.2
2.3
121.9
144.0
ug/g
0.47
310
2575
891
7834
1.19
4.44
3.3
3.0
—
—
—
0
0
725
6264
1.20
4.40
1.8
1.7
24310780.2
33480605.8
pmol/l
0.20
580
5221
851
7467
1.19
4.33
3.7
3.9
90.5
89.8
%
0.34
837
7280
637
5449
1.21
4.29
1.9
1.8
1200.1
1179.6
nmol/l
0.20
486
4136
912
8057
1.18
4.28
3.3
3.1
0.4
0.4
e6/l
0.38
706
6086
1310
11909
1.16
4.28
2.0
2.0
98.7
95.0
pmol/l
1.76
676
6153
265
2057
1.31
4.16
2.2
2.5
—
—
—
0
0
59
340
1.75
4.00
1.4
1.4
33.7
29.3
u/l
0.48
46
285
26
111
2.35
3.99
1.0
1.1
5.0
3.6
u/ml
—
5
17
570
4862
1.21
3.94
2.7
3.4
0.8
0.8
mmol/l
0.83
534
4551
764
6693
1.18
3.92
4.2
3.7
—
—
—
0
0
53
298
1.79
3.91
1.1
1.1
—
—
—
0
0
1029
9238
1.16
3.88
3.2
3.2
7.9
7.5
mmol/l
1.81
843
7782
481
4049
1.22
3.81
1.2
1.2
—
—
—
0
0
1030
9263
1.16
3.78
4.0
4.0
7.0
8.9
mg/mmol
0.86
631
5872
14
44
3.19
3.77
1.1
1.0
—
—
—
0
0
982
8809
1.16
3.72
3.3
3.3
387.5
328.2
mg/l
0.14
597
5584
370
3045
1.24
3.64
1.6
1.6
—
—
—
0
0
147
1066
1.40
3.63
1.3
1.2
2.5
1.5
u/ml
—
10
93
32
158
2.03
3.50
1.2
1.3
136.6
134.9
nmol/l
0.09
32
158
653
5702
1.18
3.46
2.8
2.8
554.0
545.2
mosm/kgh2o
0.43
563
4843
95
644
1.49
3.38
2.4
2.9
8.1
8.0
kpa
0.38
83
595
302
2455
1.25
3.33
4.5
4.1
—
—
—
0
0
150
1110
1.37
3.31
2.6
2.6
—
—
—
0
0
843
7539
1.16
3.28
3.8
3.4
—
—
—
0
0
116
823
1.42
3.27
1.2
1.1
—
—
—
0
0
2680
25880
1.16
3.26
16.1
15.5
40.1
39.7
%
1.51
1811
18348
400
3360
1.22
3.25
2.0
1.8
—
—
—
0
0
874
7843
1.15
3.24
1.6
1.6
1.4
1.4
mmol/l
0.33
715
6551
96
660
1.47
3.21
2.2
2.1
3006.5
4150.6
u/l
0.18
33
254
300
2452
1.24
3.17
3.0
3.9
1.2
1.2
mmol/l
0.16
260
2142
81
542
1.51
3.10
2.4
2.8
—
—
—
0
0
302
2477
1.24
3.09
2.4
2.8
67.2
66.5
g/l
1.03
270
2270
39
217
1.81
3.05
1.2
1.3
13.7
12.3
mmol/l
0.43
11
63
130
954
1.38
3.04
7.3
10.2
—
—
—
0
0
219
1734
1.28
3.03
1.9
1.9
1.3
1.5
g/l
0.63
196
1588
605
5307
1.17
3.02
1.5
1.5
2.3
2.5
g/l
1.15
369
3247
166
1271
1.32
2.96
1.2
1.2
—
—
—
0
0
194
1519
1.29
2.94
2.3
2.4
—
—
—
0
0
51
314
1.63
2.81
2.9
2.6
—
—
—
0
0
450
3879
1.18
2.78
5.2
6.1
1.0
1.0
mmol/l
0.19
409
3608
155
1189
1.32
2.75
5.0
5.9
0.9
0.9
%
0.30
144
1109
243
1975
1.25
2.73
4.8
5.2
—
—
—
0
0
178
1395
1.29
2.70
3.6
3.4
25.3
25.3
mmol/l
0.07
171
1348
156
1203
1.31
2.67
4.9
5.8
1.6
1.6
%
0.17
145
1121
440
3802
1.18
2.64
28.5
24.8
1.3
1.3
inr
0.04
61
532
485
4225
1.17
2.64
1.8
1.7
—
—
—
0
0
108
790
1.38
2.62
1.7
1.6
312.0
301.3
mu/l
0.12
99
719
381
3255
1.19
2.61
1.3
1.3
—
—
—
0
0
29
155
1.88
2.61
2.2
1.5
—
—
—
0
0
1375
12843
1.12
2.61
9.8
9.7
0.0
0.0
e9/l
0.87
1167
10493
100
724
1.39
2.59
1.1
1.1
7.8
4.7
u/ml
—
10
84
51
323
1.59
2.54
1.5
1.2
—
—
—
0
0
214
1730
1.25
2.54
3.5
3.3
4.4
4.4
pmol/l
0.25
189
1538
122
922
1.34
2.43
5.7
7.0
1.4
1.3
mmol/l
0.73
101
801
41
249
1.65
2.43
2.0
1.5
—
—
—
0
0
57
376
1.52
2.40
1.2
1.3
—
—
—
0
0
183
1465
1.26
2.38
2.9
2.9
0.1
0.3
e6/l
2.66
176
1429
86
617
1.40
2.37
4.7
3.4
23.6
28.5
mg/l
0.61
51
375
440
3838
1.17
2.37
1.3
1.3
—
—
—
0
0
233
1919
1.23
2.35
1.2
1.2
—
—
—
0
0
612
5475
1.14
2.33
3.1
3.1
2.4
2.5
mmol/l
1.09
534
4788
32
184
1.75
2.31
1.4
1.2
—
—
—
0
0
1001
9237
1.12
2.30
2.4
2.4
—
—
—
0
0
54
358
1.52
2.24
1.3
1.4
294.3
278.1
pmol/l
0.11
42
283
700
6336
1.13
2.23
4.9
4.6
—
—
—
0
0
2451
23730
1.11
2.19
18.3
17.6
13.6
13.7
%
1.70
2414
23182
56
377
1.49
2.18
1.3
1.4
50.4
56.0
mu/l
0.13
51
336
59
402
1.48
2.16
1.2
1.3
0.6
0.6
nmol/l
1.07
53
384
31
181
1.72
2.15
1.0
1.1
0.1
6.1
nmol/l
—
5
42
99
741
1.35
2.14
1.8
2.0
10.3
11.6
mg/l
0.92
88
678
237
1977
1.21
2.14
2.5
3.2
4.0
4.1
e9/l
0.21
185
1556
154
1227
1.27
2.11
2.0
1.5
20.0
19.5
u/ml
—
6
29
86
631
1.37
2.11
2.1
2.5
16.7
16.1
%
0.72
47
327
62
429
1.45
2.11
1.2
1.2
5.8
4.8
u/ml
0.16
22
183
67
471
1.43
2.10
1.5
1.9
1.7
1.6
mmol/l
0.07
67
459
33
198
1.67
2.08
1.3
1.3
2.4
1.0
u/ml
0.50
17
95
1078
10035
1.11
2.08
3.1
2.9
—
—
—
0
0
118
911
1.31
2.07
3.8
4.2
3.8
3.9
mmol/l
0.69
107
857
136
1073
1.28
2.03
3.5
3.9
1.3
1.3
mmol/l
0.35
136
1058
152
1216
1.26
2.03
4.9
4.7
—
—
—
0
0
193
1588
1.23
2.01
1.3
1.2
—
—
—
0
0
76
552
1.39
2.00
2.3
3.0
—
—
—
0
0
224
1874
1.21
1.98
7.2
7.3
24.8
24.5
mmol/l
0.43
208
1741
421
3719
1.15
1.94
5.3
7.0
104.7
104.3
mmol/l
1.47
408
3637
387
3399
1.16
1.93
5.9
7.5
12.0
12.2
kpa
0.50
368
3243
387
3400
1.16
1.93
5.9
7.5
5.1
5.1
kpa
0.55
368
3246
86
642
1.35
1.92
3.3
3.3
134.5
738.2
u/ml
0.85
71
591
49
331
1.49
1.91
1.7
1.5
0.3
0.3
nmol/l
0.29
37
251
347
3032
1.16
1.86
6.2
7.9
95.4
95.6
%
0.16
333
2925
74
543
1.37
1.85
2.4
2.0
201.8
200.9
pmol/l
0.03
69
511
88
665
1.33
1.83
6.8
8.1
11.2
11.3
mmol/l
0.03
77
591
88
666
1.33
1.82
6.8
8.1
104.7
105.2
mmol/l
0.35
77
592
25
145
1.73
1.81
1.6
1.3
215.6
337.5
u/l
0.75
25
133
102
793
1.29
1.75
1.2
1.2
182.1
100.6
titre
0.43
14
66
98
758
1.30
1.75
2.6
3.2
24.7
25.0
mmol/l
0.33
85
661
767
7075
1.11
1.74
2.3
2.4
—
—
—
0
0
96
741
1.30
1.74
2.0
1.9
43.3
39.7
nmol/l
0.72
90
711
613
5588
1.12
1.73
3.0
3.0
0.8
0.8
ug/l
0.28
423
3733
8
30
2.67
1.72
1.3
1.1
—
—
—
0
0
542
4911
1.12
1.70
3.0
2.7
0.9
1.1
e6/l
0.88
321
2810
28
171
1.64
1.70
1.1
1.7
6.1
7.6
u/l
0.56
20
149
201
1693
1.20
1.69
1.3
1.3
197.1
207.6
u/ml
0.09
190
1558
43
291
1.48
1.69
2.2
2.3
—
—
—
0
0
131
1059
1.25
1.65
1.8
1.9
20.7
21.6
s
1.66
109
928
209
1772
1.19
1.65
3.4
3.2
130.1
128.4
g/l
0.53
204
1725
61
444
1.38
1.64
1.3
1.7
0.6
0.8
g/l
0.97
46
344
90
697
1.30
1.61
1.3
1.3
250.2
222.0
miu/ml
0.30
43
307
103
812
1.28
1.61
1.5
1.6
0.2
0.2
g/l
0.00
94
770
91
706
1.30
1.61
1.2
1.2
3.3
3.1
u/ml
—
8
74
41
279
1.48
1.59
1.1
1.4
—
—
—
0
0
14
70
2.00
1.59
1.0
1.1
288.4
272.2
pmol/l
—
8
51
249
2153
1.17
1.57
1.1
1.2
—
—
—
0
0
379
3382
1.14
1.54
6.0
7.5
1.2
1.1
mmol/l
0.11
304
2636
105
836
1.26
1.53
1.5
1.6
1.2
1.2
g/l
0.38
96
794
10
44
2.28
1.53
1.4
1.4
133.7
111.5
ng/l
—
10
44
10
44
2.28
1.53
1.0
1.1
—
—
—
0
0
319
2816
1.15
1.53
6.5
8.3
123.7
121.5
g/l
1.15
307
2708
18
100
1.80
1.53
2.2
2.8
26.4
29.5
umol/l
0.64
12
71
15
79
1.90
1.49
1.1
1.2
41.2
39.1
g/l
—
6
41
55
401
1.38
1.49
1.1
1.1
—
—
—
0
0
46
325
1.42
1.49
6.3
5.9
7.2
7.4
mmol/l
0.23
41
275
28
178
1.58
1.48
1.0
1.0
—
—
—
0
0
218
1876
1.17
1.47
6.4
9.1
93.2
93.8
%
0.61
218
1870
55
402
1.37
1.47
1.1
1.1
—
—
—
0
0
8
169
0.47
1.46
1.0
1.1
—
—
—
0
0
235
2038
1.16
1.44
2.6
2.2
12.4
12.8
nmol/l
0.35
202
1807
39
269
1.45
1.44
2.0
2.5
1.1
1.1
e9/l
0.26
26
164
29
188
1.55
1.42
1.0
1.1
—
—
—
0
0
313
2776
1.14
1.41
3.8
3.7
—
7.4
—
0
13
466
4235
1.12
1.41
2.6
2.5
2.4
2.3
g/l
2.48
426
3925
49
669
0.73
1.41
1.4
1.3
—
—
—
0
0
107
864
1.25
1.41
1.4
1.4
278.2
280.5
ug/g
0.03
57
504
44
313
1.41
1.39
1.4
1.3
283.9
277.9
mosm/kgh2o
0.83
34
243
254
2225
1.15
1.38
4.4
4.3
0.1
0.4
%
0.76
61
553
8
163
0.49
1.35
15.9
12.5
541.8
837.1
nmol/l
—
8
156
254
2229
1.15
1.35
4.0
4.0
93.4
92.2
ng/l
0.07
208
1932
48
349
1.38
1.34
1.2
1.3
—
—
nmol/l
—
0
0
17
97
1.76
1.34
1.0
1.2
—
—
—
0
0
24
151
1.59
1.34
1.5
1.8
3.2
3.2
u/field
0.01
19
109
39
274
1.43
1.32
1.2
1.5
—
—
—
0
0
45
615
0.73
1.32
2.0
1.9
1.0
0.8
nmol/l
0.92
39
508
34
233
1.46
1.31
1.1
1.0
287.8
288.8
mg/l
0.03
28
211
48
351
1.37
1.31
1.3
1.5
—
—
—
0
0
35
497
0.70
1.29
1.3
1.2
20.5
42.9
u/l
1.86
27
428
9
173
0.52
1.29
1.2
1.3
—
—
—
0
0
335
3006
1.13
1.28
1.6
1.6
—
—
—
0
0
250
2201
1.15
1.28
3.2
3.0
4.4
4.6
kpa
0.94
244
2121
10
48
2.09
1.27
1.2
1.3
—
—
—
0
0
40
285
1.41
1.27
1.4
1.4
31.2
31.7
%
0.02
19
173
348
3132
1.12
1.27
3.9
4.1
7.3
25.2
ug/l
3.01
280
2562
85
678
1.26
1.27
3.0
4.8
2.2
2.6
mmol/l
0.73
56
475
21
130
1.62
1.26
3.0
2.9
—
—
—
0
0
113
1361
0.82
1.24
1.6
1.7
—
—
—
0
0
27
179
1.51
1.23
1.5
2.5
0.1
0.2
e9/l
0.64
27
174
34
237
1.44
1.22
2.2
2.2
2.2
1.8
u/field
0.14
18
92
39
281
1.39
1.18
1.3
1.4
0.4
0.4
g/l
0.08
24
202
39
281
1.39
1.18
1.3
1.4
3.2
2.9
g/l
0.48
25
202
25
165
1.52
1.17
1.2
1.2
1.1
1.0
ratio
—
5
61
498
4591
1.10
1.17
2.6
2.5
13.9
13.1
umol/l
1.63
454
4264
39
282
1.39
1.16
1.3
1.4
7.5
6.9
g/l
0.41
24
204
0
34
0.00
1.16
0.0
11.5
—
—
—
0
0
61
473
1.29
1.16
1.0
1.1
—
—
—
0
0
432
3959
1.10
1.15
2.7
2.6
23.5
22.9
%
0.39
367
3389
30
207
1.45
1.15
2.3
2.2
14.7
13.6
%
0.15
12
86
297
2668
1.12
1.14
3.7
3.8
2.1
2.0
mmol/l
0.18
244
2160
279
2499
1.13
1.12
4.4
4.2
0.7
0.9
%
0.50
74
720
265
2368
1.13
1.11
4.5
4.3
0.1
0.1
%
0.41
67
657
155
1335
1.17
1.10
3.1
2.6
0.6
0.7
%
0.56
150
1277
48
364
1.32
1.08
1.3
1.5
55.7
59.3
%
0.23
22
226
32
227
1.41
1.07
1.2
1.2
44.0
128.0
titre
—
5
50
287
2585
1.12
1.06
5.2
6.9
1.3
1.4
mmol/l
0.11
282
2493
394
3612
1.10
1.05
1.6
1.6
—
—
—
0
0
51
392
1.31
1.05
6.0
6.8
11.4
11.8
mg/l
0.30
46
367
303
2744
1.11
1.03
2.5
2.4
38.9
55.7
u/l
0.45
259
2369
124
1056
1.18
1.02
1.7
1.6
—
—
—
0
0
53
412
1.29
1.01
2.5
2.7
—
—
—
0
0
2455
24078
1.07
1.01
20.5
18.7
333.2
332.3
g/l
5.85
2444
23897
296
2682
1.11
1.00
3.7
3.7
5.8
5.8
kpa
0.21
291
2595
38
282
1.35
1.00
1.3
1.4
—
—
—
0
0
54
422
1.28
1.00
1.2
1.2
—
—
—
0
0
276
2492
1.12
0.99
3.0
2.9
206.7
196.4
ng/l
0.14
255
2267
20
297
0.67
0.99
1.5
1.5
—
—
—
0
0
97
811
1.20
0.99
2.9
4.5
7.4
7.4
ph
0.04
83
668
361
3308
1.10
0.99
2.6
2.6
1.8
1.8
%
0.08
318
2933
11
61
1.81
0.98
1.0
1.1
0.7
0.7
umol/24h
—
6
34
9
50
1.80
0.96
6.9
8.1
—
—
—
0
0
10
54
1.85
0.96
1.1
1.4
—
—
—
0
0
11
186
0.59
0.95
1.5
1.3
—
1.4
—
0
10
18
117
1.54
0.93
1.7
2.1
—
—
—
0
0
91
763
1.20
0.92
3.0
3.1
1.5
1.6
mg/l
0.29
81
699
20
134
1.50
0.91
1.1
1.1
—
—
—
0
0
77
636
1.22
0.90
2.0
2.2
130.9
128.8
g/l
0.34
60
460
41
314
1.31
0.90
3.0
4.4
—
—
—
0
0
19
127
1.50
0.88
1.2
1.2
—
—
—
0
0
129
1119
1.16
0.88
1.1
1.1
—
—
—
0
0
71
584
1.22
0.88
3.6
3.3
7.2
7.5
mmol/l
0.68
71
569
225
2028
1.12
0.86
1.3
1.4
—
—
—
0
0
75
623
1.21
0.85
3.5
3.1
1.5
1.6
mmol/l
0.13
75
604
6
31
1.94
0.84
1.3
1.4
—
—
—
0
0
211
1901
1.12
0.83
3.2
3.1
—
—
—
0
0
64
525
1.22
0.82
1.3
1.5
—
—
—
0
0
62
508
1.22
0.81
1.6
1.6
—
—
—
0
0
125
1091
1.15
0.80
1.4
1.3
27.9
31.1
iu/l
0.51
100
929
18
122
1.48
0.80
1.7
2.1
7.1
8.5
%
0.36
18
117
45
356
1.27
0.80
1.2
1.1
2.6
2.2
u/ml
0.14
18
150
0
24
0.00
0.79
0.0
1.3
—
—
—
0
0
250
2280
1.10
0.79
4.4
4.0
0.6
0.6
%
0.03
58
507
20
139
1.44
0.79
2.2
1.6
16.4
9.4
ug/l
0.48
15
115
203
1831
1.12
0.79
1.3
1.2
102.3
151.9
iu/ml
1.39
84
666
263
2405
1.10
0.79
6.4
8.4
—
—
—
0
0
5
96
0.52
0.78
2.6
2.2
—
—
—
0
0
57
466
1.23
0.77
1.1
1.1
—
—
—
0
0
74
622
1.19
0.76
1.5
1.7
—
—
—
0
0
6
34
1.77
0.76
1.0
1.2
1.4
1.8
umol/24h
—
6
34
0
28
0.00
0.76
0.0
1.0
—
8.1
—
0
10
16
107
1.50
0.76
1.1
1.0
—
—
—
0
0
116
1013
1.15
0.75
2.0
2.2
299.6
738.9
ug/l
1.19
109
953
25
336
0.74
0.75
1.4
1.4
—
—
—
0
0
39
306
1.28
0.75
1.1
1.2
—
—
—
0
0
86
735
1.17
0.74
1.1
1.2
—
—
—
0
0
37
289
1.28
0.73
3.6
3.8
62.0
56.9
%
0.59
26
185
84
717
1.18
0.73
2.7
2.0
—
—
—
0
0
42
524
0.80
0.73
1.4
1.6
—
—
—
0
0
441
4140
1.07
0.73
2.1
2.1
—
—
—
0
0
25
334
0.75
0.73
1.4
1.4
—
—
—
0
0
23
310
0.74
0.71
1.4
1.6
—
—
—
0
0
21
287
0.73
0.71
1.6
1.5
—
—
—
0
0
116
1019
1.14
0.71
3.1
3.1
0.2
0.3
g/l
1.82
39
403
27
203
1.33
0.70
1.2
1.1
—
—
—
0
0
20
143
1.40
0.70
1.1
1.0
—
—
—
0
0
776
7432
1.06
0.69
6.4
6.8
—
—
—
0
0
9
145
0.62
0.69
13.8
11.4
0.6
0.6
mmol/l
—
9
134
5
27
1.85
0.68
1.2
1.2
—
—
—
0
0
7
42
1.67
0.68
1.4
1.6
—
—
—
0
0
25
187
1.34
0.68
1.3
1.4
2123.2
1952.5
ml
—
5
35
84
724
1.16
0.67
2.7
2.1
—
—
—
0
0
123
1090
1.13
0.67
2.1
2.4
9.9
10.4
g/l
0.79
102
927
27
205
1.32
0.67
2.8
2.4
—
—
—
0
0
108
949
1.14
0.67
3.3
3.5
40.1
119.1
mg/l
0.72
85
768
268
2477
1.09
0.67
2.9
2.6
71.8
70.8
e9/l
0.15
208
1868
7
43
1.63
0.66
8.9
12.1
4.4
6.0
mmol/l
—
7
43
33
418
0.79
0.66
4.5
5.3
360.0
359.4
umol/l
0.01
28
363
22
294
0.75
0.66
2.5
3.0
8.6
38.4
mg/l
2.78
17
218
240
2210
1.09
0.65
1.3
1.3
—
—
—
0
0
10
62
1.61
0.65
7.2
8.1
—
—
—
0
0
39
313
1.25
0.65
1.2
1.2
—
—
—
0
0
85
736
1.16
0.65
2.8
2.3
90.8
100.6
ug/min
0.08
43
454
84
729
1.16
0.63
2.7
2.1
—
—
—
0
0
19
138
1.38
0.62
1.0
1.2
—
4.3
—
0
9
42
342
1.23
0.62
1.2
1.2
—
—
—
0
0
12
176
0.68
0.61
1.2
1.0
—
—
—
0
0
63
535
1.18
0.61
1.4
1.4
64.2
61.4
mmol/l
0.21
49
432
70
600
1.17
0.61
3.5
3.8
55.8
57.5
%
0.48
70
600
5
30
1.67
0.61
1.2
1.1
—
—
—
0
0
38
307
1.24
0.61
1.0
1.1
4.7
2.9
u/ml
0.28
15
111
9
139
0.65
0.60
1.7
1.4
—
—
—
0
0
84
732
1.15
0.60
2.7
2.1
—
—
—
0
0
0
21
0.00
0.60
0.0
4.4
—
15.9
—
0
21
25
322
0.77
0.59
1.4
1.4
29840.8
81810.4
e6/l
1.15
17
202
11
72
1.53
0.59
1.0
1.1
—
—
—
0
0
11
72
1.53
0.59
1.0
1.1
—
—
—
0
0
11
72
1.53
0.59
1.0
1.1
—
—
—
0
0
7
114
0.61
0.58
1.7
1.6
—
—
—
0
0
132
1189
1.11
0.57
2.2
2.0
2.4
2.3
ug/l
0.02
106
1063
27
342
0.79
0.57
1.4
1.5
—
—
—
0
0
29
229
1.27
0.56
2.6
1.9
24.7
5.5
umol/l
0.74
19
166
29
229
1.27
0.56
1.1
1.1
—
57.3
—
0
9
5
89
0.56
0.56
1.0
2.3
—
—
—
0
0
21
159
1.32
0.55
1.6
2.1
—
—
—
0
0
23
177
1.30
0.54
2.3
2.8
44.4
40.2
%
—
7
58
6
38
1.58
0.54
1.0
1.3
—
—
—
0
0
6
38
1.58
0.54
1.0
1.3
—
—
—
0
0
6
38
1.58
0.54
1.0
1.3
—
—
—
0
0
16
116
1.38
0.54
6.8
6.2
84.3
61.4
mg/l
—
8
82
28
350
0.80
0.54
1.3
1.3
—
—
—
0
0
42
349
1.21
0.53
3.4
2.5
—
—
—
0
0
47
395
1.19
0.53
1.6
1.9
89.8
89.3
%
0.29
47
389
39
470
0.83
0.53
1.2
1.1
49.2
1332.9
iu/ml
—
10
100
20
152
1.32
0.52
1.4
1.2
—
—
—
0
0
351
3318
1.06
0.51
3.0
2.8
7.7
8.2
umol/l
0.16
299
2903
35
287
1.22
0.51
1.2
1.4
388063.5
85512.7
e6/l
0.71
26
201
23
179
1.29
0.51
2.0
2.0
2.2
2.3
ug/l
0.07
18
151
32
391
0.82
0.51
1.1
1.0
6.1
4.3
u/ml
0.32
14
191
29
358
0.81
0.51
1.4
1.4
3666.0
1716.8
e6/l
0.59
22
269
67
584
1.15
0.50
1.9
1.6
—
—
—
0
0
103
924
1.12
0.50
3.4
3.5
1.4
2.1
ratio
0.46
11
72
13
92
1.41
0.50
1.3
1.3
—
—
—
0
0
12
84
1.43
0.49
1.7
1.7
—
—
—
0
0
31
378
0.82
0.49
1.1
1.1
1.0
1.2
u/ml
0.15
14
153
105
948
1.11
0.47
3.4
3.5
29.3
67.5
mg/l
1.78
82
767
7
48
1.46
0.46
2.0
1.5
—
—
—
0
0
172
1592
1.08
0.46
7.8
10.5
—
—
—
0
0
33
397
0.83
0.46
1.4
1.5
35.8
32.5
g/l
0.86
33
360
8
117
0.68
0.45
1.6
1.9
22.1
19.8
ug/l
—
8
105
51
440
1.16
0.45
1.4
1.3
—
—
—
0
0
28
228
1.23
0.45
1.1
1.4
1.8
1.2
promille
1.21
21
177
12
86
1.40
0.44
1.4
1.8
—
—
—
0
0
301
2852
1.06
0.43
2.2
2.2
0.2
0.2
g/l
0.43
276
2664
6
91
0.66
0.42
1.8
1.9
—
—
—
0
0
26
212
1.23
0.42
2.8
1.5
4.3
4.4
ug/l
0.02
21
179
19
149
1.28
0.41
2.6
2.5
9.3
9.5
mmol/l
0.07
14
117
0
16
0.00
0.41
0.0
2.1
—
1.9
—
0
5
0
16
0.00
0.41
0.0
1.8
—
—
—
0
0
0
16
0.00
0.41
0.0
1.3
—
32.3
—
0
7
0
16
0.00
0.41
0.0
1.3
—
23.0
—
0
5
0
17
0.00
0.40
0.0
3.8
—
—
—
0
0
0
17
0.00
0.40
0.0
1.2
—
—
—
0
0
15
114
1.32
0.40
1.1
1.3
—
0.3
—
0
10
78
701
1.12
0.40
1.7
1.7
15314.8
13570.8
e6/l
0.11
53
515
63
560
1.13
0.39
3.2
2.1
—
—
—
0
0
20
248
0.81
0.39
3.1
2.2
674.9
636.2
ml
0.17
15
162
95
865
1.10
0.39
2.6
3.6
—
—
—
0
0
164
1530
1.08
0.39
6.7
9.5
24.5
24.3
mmol/l
0.24
150
1437
46
400
1.15
0.39
1.1
1.1
1.5
1.5
g/l
0.22
40
358
196
1842
1.07
0.38
1.7
1.6
—
—
—
0
0
26
215
1.21
0.38
1.7
1.4
—
—
—
0
0
18
225
0.80
0.38
1.8
1.5
0.9
1.0
g/l
0.89
18
225
25
206
1.22
0.38
1.4
2.0
7.2
6.9
mmol/l
0.08
15
132
68
609
1.12
0.37
1.1
1.2
—
—
—
0
0
143
1330
1.08
0.37
2.0
1.9
—
—
—
0
0
8
113
0.71
0.37
1.1
1.1
—
—
—
0
0
75
677
1.11
0.36
2.9
4.0
—
—
—
0
0
25
208
1.20
0.35
1.0
1.2
—
—
—
0
0
100
919
1.09
0.35
2.2
2.3
39.3
37.7
g/l
2.53
86
789
6
43
1.40
0.35
1.3
1.3
3.6
760005.2
nmol/l
—
6
35
54
480
1.13
0.34
4.1
3.6
1.5
1.4
%
0.07
44
374
18
145
1.24
0.33
1.2
1.2
—
—
—
0
0
31
265
1.17
0.33
7.3
5.2
370.6
64.5
u/ml
0.43
12
73
93
857
1.09
0.32
1.2
1.2
—
—
—
0
0
139
1482
0.94
0.31
4.3
3.4
—
—
—
0
0
7
52
1.35
0.31
1.6
1.2
—
—
—
0
0
73
667
1.10
0.30
2.9
2.2
—
—
—
0
0
16
129
1.24
0.30
2.7
3.9
—
—
—
0
0
279
2677
1.05
0.29
7.2
7.6
9.9
10.0
mmol/l
0.03
258
2558
17
206
0.82
0.29
1.4
1.5
19.9
189.0
pmol/l
—
6
70
14
112
1.25
0.28
1.4
2.8
306.0
151.1
umol/l
—
8
66
14
112
1.25
0.28
1.1
1.1
1540.9
1561.6
miu/ml
0.03
14
112
12
94
1.28
0.28
1.0
1.1
—
—
—
0
0
11
85
1.30
0.28
1.3
1.5
—
—
—
0
0
27
312
0.86
0.28
1.1
1.2
—
—
—
0
0
8
63
1.27
0.27
1.4
2.2
—
—
—
0
0
10
77
1.30
0.26
1.0
1.1
—
—
—
0
0
17
141
1.21
0.26
2.6
3.8
—
—
—
0
0
77
714
1.08
0.25
3.4
3.6
—
—
—
0
0
9
75
1.20
0.25
2.6
2.3
—
—
—
0
0
34
302
1.13
0.24
1.2
1.2
—
—
—
0
0
770
7850
0.98
0.24
1.4
1.4
—
—
—
0
0
21
180
1.17
0.23
9.9
6.8
—
—
—
0
0
40
443
0.90
0.23
1.1
1.1
4.2
1.7
u/ml
0.28
15
175
37
332
1.12
0.23
1.5
1.8
—
—
—
0
0
130
1370
0.95
0.23
3.9
4.0
24.0
24.2
mmol/l
0.23
116
1231
468
4564
1.03
0.22
3.2
2.9
2.3
2.5
e6/l
0.13
248
2480
36
323
1.12
0.22
2.3
2.0
—
—
—
0
0
10
79
1.27
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
6.1
—
424.6
—
0
11
0
11
0.00
0.21
0.0
1.0
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
752.6
—
0
11
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
0.1
—
0
5
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
23
201
1.15
0.21
1.5
2.5
631.4
715.7
e6/l
—
10
84
60
556
1.08
0.21
1.4
1.4
—
—
—
0
0
5
43
1.16
0.21
2.6
1.1
—
—
—
0
0
5
43
1.16
0.21
1.2
1.6
—
—
—
0
0
8
105
0.76
0.21
1.0
1.1
—
—
—
0
0
32
356
0.90
0.21
1.3
1.4
—
—
—
0
0
32
356
0.90
0.21
1.3
1.4
—
—
—
0
0
32
356
0.90
0.21
1.3
1.4
—
—
—
0
0
32
356
0.90
0.21
1.3
1.4
—
—
—
0
0
47
512
0.92
0.21
1.3
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.6
—
12.6
—
0
13
39
354
1.10
0.20
1.5
1.8
22.3
26.4
ug/l
0.29
39
349
23
261
0.88
0.20
1.1
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
13
154
0.84
0.19
1.6
2.1
115.6
190.7
ug/min
—
5
33
82
775
1.06
0.18
1.2
1.2
—
—
—
0
0
64
682
0.94
0.17
2.6
2.2
—
—
—
0
0
7
62
1.13
0.17
1.4
2.4
—
—
—
0
0
21
186
1.13
0.17
1.3
1.1
31.3
34.8
mmol/l
0.30
15
165
24
267
0.90
0.16
1.1
1.2
—
—
—
0
0
51
476
1.07
0.16
1.7
1.4
—
—
—
0
0
19
168
1.13
0.15
2.2
1.7
—
—
—
0
0
9
78
1.15
0.15
3.6
1.6
—
—
—
0
0
25
226
1.11
0.15
1.0
1.0
783.7
723.2
ng/l
0.20
14
145
25
226
1.11
0.15
1.0
1.0
253.3
322.3
ng/l
0.88
15
148
9
83
1.08
0.14
2.0
2.5
—
—
—
0
0
7
88
0.80
0.14
10.0
5.3
—
—
—
0
0
139
1342
1.04
0.14
1.7
1.8
1.4
1.5
g/l
0.73
120
1153
23
208
1.11
0.14
1.6
1.5
—
72.8
—
0
19
63
597
1.06
0.14
3.0
3.2
0.8
0.8
nmol/l
0.05
53
456
235
2409
0.97
0.13
1.4
1.4
—
—
—
0
0
52
491
1.06
0.13
1.5
1.4
88.8
119.9
u/ml
1.45
15
94
10
85
1.18
0.12
1.1
1.1
—
—
—
0
0
265
2705
0.98
0.12
1.3
1.4
—
—
—
0
0
10
116
0.86
0.12
3.4
2.3
—
—
—
0
0
279
2737
1.02
0.11
1.3
1.5
—
—
—
0
0
14
124
1.13
0.11
1.1
1.0
0.6
0.5
u/ml
—
6
34
18
163
1.10
0.10
1.5
1.3
1.1
1.2
nmol/l
0.07
13
128
5
45
1.11
0.09
1.2
1.1
—
—
—
0
0
28
299
0.94
0.09
1.8
2.0
—
—
—
0
0
21
227
0.92
0.09
1.2
1.2
—
—
—
0
0
30
282
1.06
0.09
1.0
1.1
10.1
3.4
u/ml
—
10
106
7
64
1.09
0.08
1.0
1.1
—
—
—
0
0
37
388
0.95
0.07
1.3
1.2
—
—
—
0
0
90
876
1.03
0.07
1.1
1.1
—
—
—
0
0
8
77
1.04
0.07
1.0
1.9
0.5
1.2
mmol/l
—
8
71
64
620
1.03
0.07
2.8
2.8
—
—
—
0
0
8
91
0.88
0.06
1.0
1.0
—
—
—
0
0
8
92
0.87
0.06
1.1
1.2
—
—
—
0
0
8
93
0.86
0.06
1.1
1.1
—
—
—
0
0
30
285
1.05
0.06
1.5
1.7
—
—
—
0
0
49
508
0.96
0.06
1.4
1.3
—
—
—
0
0
71
729
0.97
0.06
5.8
4.3
—
—
—
0
0
25
237
1.06
0.05
2.8
1.9
12.5
11.3
%
0.77
25
237
14
129
1.09
0.05
1.1
1.0
0.4
1.0
u/ml
—
5
46
30
287
1.05
0.05
1.1
1.2
—
—
—
0
0
16
171
0.94
0.05
1.8
1.6
—
—
—
0
0
12
130
0.92
0.04
3.6
2.6
—
—
—
0
0
50
514
0.97
0.04
1.1
1.2
253.3
285.1
u/ml
0.41
34
313
29
302
0.96
0.04
1.9
3.7
—
—
—
0
0
109
1107
0.98
0.04
3.7
3.4
741.1
4534.7
u/ml
0.82
95
944
191
1929
0.99
0.03
1.3
1.4
—
—
—
0
0
47
482
0.97
0.03
4.0
2.9
—
—
—
0
0
72
709
1.02
0.02
1.5
1.8
2.5
4.6
iu/l
5.08
21
244
15
158
0.95
0.02
1.3
1.3
—
—
—
0
0
37
361
1.03
0.02
1.1
1.1
1.8
2.1
u/ml
—
9
85
40
391
1.02
0.02
2.0
2.5
—
—
—
0
0
153
1542
0.99
0.02
1.4
1.5
—
—
—
0
0
29
282
1.03
0.02
1.1
1.3
1.4
1.4
nmol/l
0.11
24
257
33
322
1.03
0.01
4.9
2.8
—
—
—
0
0
65
641
1.01
0.01
2.8
2.8
32.5
36.8
umol/l
0.78
55
541
16
153
1.05
0.01
2.2
1.6
—
—
—
0
0
23
236
0.97
0.00
1.0
1.1
—
—
—
0
0
30
298
1.01
0.00
2.2
2.5
—
—
—
0
0
14
141
0.99
0.00
1.0
2.4
4582.7
1147.7
u/ml
0.38
14
141
15
151
0.99
0.00
1.8
2.2
—
—
—
0
0
48
476
1.01
0.00
1.4
1.4
—
—
—
0
0
17
173
0.98
0.00
1.5
3.9
—
—
—
0
0
0
9
0.00
0.00
0.0
9.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
5
56
0.89
0.00
7.2
3.0
—
—
—
0
0
7
72
0.97
0.00
1.4
1.7
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.4
—
1.9
—
0
7
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
2.1
—
—
—
0
0
8
89
0.90
0.00
1.0
1.1
—
—
—
0
0
8
87
0.92
0.00
1.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.0
—
25.8
—
0
5
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
94
0.96
0.00
1.2
1.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
9
93
0.97
0.00
1.3
1.4
3.1
3.2
mmol/l
—
9
83
5
58
0.86
0.00
1.4
1.2
1.5
1.7
mmol/l
—
5
40
6
65
0.92
0.00
1.5
1.3
—
—
—
0
0
8
85
0.94
0.00
1.6
1.9
—
—
—
0
0
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
0.00
0.0
1.6
—
1.6
—
0
5
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_VESTIBNEUR and mortality.

Females

Parameter HR [95% CI] p-value
H8_VESTIBNEUR 0.785 [0.71, 0.87] < 0.001
Birth year 0.997 [0.99, 1.01] 0.546

During the follow-up period (1.1.1998 — 31.12.2019), 927 out of 9696 females with H8_VESTIBNEUR died.

Males

Parameter HR [95% CI] p-value
H8_VESTIBNEUR 0.686 [0.61, 0.77] < 0.001
Birth year 0.988 [0.98, 1.0] 0.009

During the follow-up period (1.1.1998 — 31.12.2019), 874 out of 8342 males with H8_VESTIBNEUR died.

Mortality risk

Mortality risk for people of age

years, who have H8_VESTIBNEUR.

N-year risk Females Males
1 0.077% 0.117%
5 0.463% 0.769%
10 1.285% 1.988%
15 2.53% 3.927%
20 4.332% 6.882%

Relationships between endpoints

Index endpoint: H8_VESTIBNEUR – Vestibular neuronitis

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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