myocardial infarction: Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
329 |
4. Check minimum number of eventsNone |
329 |
5. Include endpointsNone |
329 |
6. Filter based on genotype QC (FinnGen only) |
321 |
Control definitions (FinnGen only)
- Control exclude
- I9_ISCHHEART
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- I20-I25
- Name in latin
- Aliquae complicationes post infarctum myocardii acutum
Similar endpoints
↥List of similar endpoints to
Complications following myocardial infarction
based on the number of shared cases.
Similar with more cases:
- Ischaemic heart disease, wide definition
- Ischemic heart diseases
- Cardiovascular diseases (excluding rheumatic etc)
- Cardiovascular diseases
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 4502 | 1945 | 2459 |
| Only index persons | 2275 | 934 | 1341 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.07 |
| Only index persons | 0.04 | 0.03 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 74.10 | 77.64 | 71.22 |
| Only index persons | 72.79 | 77.27 | 69.66 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 321 | 90 | 231 |
| Unadjusted period prevalence (%) | 0.09 | 0.03 | 0.11 |
| Median age at first event (years) | 72.56 | 73.76 | 72.09 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 329
- Matched controls
- 3290
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I25.1
ICD-10 Finland
Atherosclerotic heart disease
150.9
256.8
129
14
I23.0
ICD-10 Finland
Haemopericardium as current complication following acute myocardial infarction
+∞
209.5
178
*
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
29.0
149.4
110
56
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
+∞
127.6
114
*
I25.2
ICD-10 Finland
Old myocardial infarction
+∞
88.6
81
*
213
Kela drug reimbursment
Fat metabolism disorder associated with chronic coronary artery disease
34.2
64.5
42
14
AN1
HP
Coronary angiography
193.9
62.4
63
*
81
HP
Angiography of the heart and coronary arteries
27.3
61.2
43
18
I21.9
ICD-10 Finland
Acute myocardial infarction, unspecified
+∞
60.3
56
*
C01DA14
ATC
isosorbide mononitrate; oral
9.4
58.8
81
111
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
175.3
56.9
58
*
I21.0
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
53.6
50
*
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
+∞
45.9
43
*
I20.81
ICD-10 Finland
Other angina pectoris stenosed coronary artery
+∞
43.7
41
*
I23.1
ICD-10 Finland
Atrial septal defect as current complication following acute myocardial infarction
+∞
37.2
35
*
I21.2
ICD-10 Finland
Acute transmural myocardial infarction of other sites
+∞
37.2
35
*
I21.1
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
36.1
34
*
I23.6
ICD-10 Finland
Thrombosis of atrium, auricular appendage, and ventricle as current complications following acute myocardial infarction
+∞
33.9
32
*
Z95.1
ICD-10 Finland
Presence of aortocoronary bypass graft
+∞
33.9
32
*
I23.2
ICD-10 Finland
Ventricular septal defect as current complication following acute myocardial infarction
+∞
33.9
32
*
FN1YT
NOMESCO Finland
Percutaneous insertion of coronary artery stent
+∞
33.9
32
*
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
4.7
32.8
95
261
I23.8
ICD-10 Finland
Other current complications following acute myocardial infarction
+∞
31.8
30
*
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
+∞
30.7
29
*
I20.09
ICD-10 Finland
Unstable angina
+∞
29.6
28
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
+∞
29.6
28
*
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
306.2
28.2
28
*
B01AC04
ATC
clopidogrel; oral
5.0
27.2
68
164
I20.99
ICD-10 Finland
Angina pectoris, unspecified
101.7
26.1
28
*
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
63.3
25.4
29
5
FNA01
NOMESCO Finland
Anastomosis to coronary artery from internal mammary artery, one distal anastamosis
+∞
25.3
24
*
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
3.7
24.6
100
345
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
+∞
24.3
23
*
I21.01
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
24.3
23
*
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
134.8
23.9
25
*
I21.99
ICD-10 Finland
Myocardial infarction (acute) UNS unspecified coronary artery status
+∞
23.2
22
*
I20.90
ICD-10 Finland
Angina pectoris, unspecified
+∞
21.1
20
*
I21.19
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
21.1
20
*
Z95.5
ICD-10 Finland
Presence of coronary angioplasty implant and graft
223.6
20.8
21
*
I20.01
ICD-10 Finland
Unstable angina
+∞
20.0
19
*
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
7.9
18.9
27
37
201
Kela drug reimbursment
Chronic cardiac insufficiency
5.8
18.7
36
68
I21.09
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
17.9
17
*
I21.00
ICD-10 Finland
Acute transmural myocardial infarction of anterior wall
+∞
17.9
17
*
AN3
HP
Balloon angioplasty and metallic stent
+∞
17.9
17
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.4
17.2
74
260
82
HP
Single vessel balloon catheter extension
+∞
16.8
16
*
11
HP
Coronary artery bypass surgery
+∞
16.8
16
*
I25.5
ICD-10 Finland
Ischaemic cardiomyopathy
+∞
16.8
16
*
I20.00
ICD-10 Finland
Unstable angina
178.7
16.7
17
*
I21.11
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
15.7
15
*
I20.89
ICD-10 Finland
Other angina pectoris unspecified coronary artery status
167.6
15.6
16
*
B01AA03
ATC
warfarin; systemic
2.7
15.1
113
537
C09AA05
ATC
ramipril; oral
2.6
14.3
108
513
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.1
13.7
66
246
B01AC06
ATC
acetylsalicylic acid; oral
17.2
13.6
21
13
FXG00
NOMESCO Finland
Insertion and use of IABP
+∞
13.6
13
*
AN2
HP
Balloon angioplasty, including several vessels
+∞
13.6
13
*
I23.5
ICD-10 Finland
Rupture of papillary muscle as current complication following acute myocardial infarction
+∞
13.6
13
*
I21.10
ICD-10 Finland
Acute transmural myocardial infarction of inferior wall
+∞
13.6
13
*
FNC20
NOMESCO Finland
Aorto-coronary venous bypass with two distal anastomoses
+∞
13.6
13
*
I21.90
ICD-10 Finland
Myocardial infarction (acute) UNS no detected stenosis of the coronary artery
+∞
13.6
13
*
AA1
HP
Conventional CABG
+∞
12.6
12
*
I50.1
ICD-10 Finland
Left ventricular failure
5.0
11.9
26
55
C07AB02
ATC
metoprolol; systemic
2.6
11.7
81
365
AP1
HP
Catheterization of the left side of the heart
+∞
11.5
11
*
AN4
HP
Balloon angioplasty and drug eluding stent
+∞
11.5
11
*
4100X
ICD-9 Finland
Acute myocardial infarction, Of anterolateral wall[INFARCTUS MYOCARDII ACUTUS DEFINITUS,MÄÄRITTELEMÄT]
+∞
11.5
11
*
I21.40
ICD-10 Finland
Acute subendocardial infarction no detected stenosis of the coronary artery
+∞
11.5
11
*
R07.4
ICD-10 Finland
Chest pain, unspecified
2.5
10.5
77
355
FHA20
NOMESCO Finland
Closure of VSR in posteroseptal myocardial infarction
+∞
10.5
10
*
WX872
NOMESCO Finland
Intensive care
8.8
9.7
20
24
FL1AC
NOMESCO Finland
Left cardioangiography
+∞
9.4
9
*
FNC10
NOMESCO Finland
Aorto-coronary venous bypass with single distal anastomosis
+∞
9.4
9
*
K76
ICPC
Ischaemic heart dis without angina
51.4
8.7
10
*
R99
ICD-10 Finland
Other ill-defined and unspecified causes of mortality
4.8
8.7
20
44
C01BD01
ATC
amiodarone; systemic
12.0
8.7
15
13
Z95.2
ICD-10 Finland
Presence of prosthetic heart valve
28.3
8.5
11
*
B01AC24
ATC
ticagrelor; oral
92.3
8.5
9
*
FN1BT
NOMESCO Finland
Extensive endovascular dilatation of coronary (PTCA) arteries
+∞
8.4
8
*
FNC30
NOMESCO Finland
Aorto-coronary venous bypass with three distal anastomoses
+∞
8.4
8
*
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
+∞
8.4
8
*
I50.9
ICD-10 Finland
Heart failure, unspecified
2.3
8.3
71
349
I25
ICD-10 Finland
Chronic ischaemic heart disease
17.7
8.1
12
7
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
3.7
8.0
26
75
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.3
7.7
65
317
C03DA01
ATC
spironolactone; oral
2.6
7.6
48
204
ZXD00
NOMESCO Finland
Emergency procedure
7.4
7.6
17
24
A98
ICPC
Health maint/preventive medicine
0.5
7.5
171
2216
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
81.9
7.4
8
*
I23.3
ICD-10 Finland
Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
+∞
7.3
7
*
FN2AB
NOMESCO Finland
Percutaneous transluminal coronary angioplasty (PTCA), drug-eluting balloon
+∞
7.3
7
*
I23
ICD-10 Finland
Certain current complications following acute myocardial infarction
+∞
7.3
7
*
I47.2
ICD-10 Finland
Ventricular tachycardia
10.4
7.1
13
13
ZXD05
NOMESCO Finland
Urgent procedure
2.0
7.0
92
531
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
6.9
18
44
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
6.9
45
195
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
10.3
6.6
12
12
TPH07
NOMESCO Finland
Cathetrisation of artery
2.7
6.5
37
150
I21.97
ICD-10 Finland
Suspected acute myocardial infarction
71.2
6.4
7
*
280
Kela drug reimbursment
Clopidogrel
71.2
6.4
7
*
C08CA07
ATC
nisoldipine; oral
14.7
6.4
10
7
I21.4
ICD-10 Finland
Acute subendocardial myocardial infarction
+∞
6.3
6
*
FLC10
NOMESCO Finland
Repair of wall of left ventricle using patch
+∞
6.3
6
*
AM2
HP
Surgery of infarction complication eg VSR, aneurysm, rupture of papillary muscle
+∞
6.3
6
*
I20.80
ICD-10 Finland
Other angina pectoris no detected stenosis of coronary artery
+∞
6.3
6
*
4120B
ICD-9 Finland
Old myocardial infarction[STATUS POST INFARCTUM CORDIS,AHTAUTUNUT]
+∞
6.3
6
*
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
6.1
61
318
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
24
67
3.79
7.73
3.2
2.3
0.41
0.38
u/ml
0.13
13
38
40
155
2.80
7.61
3.6
1.9
6.98
3.95
ug/l
0.90
30
117
178
2276
0.53
7.47
34.5
23.0
130.55
133.76
g/l
1.51
168
2200
178
2276
0.53
7.47
34.2
22.8
4.32
4.41
e12/l
1.21
165
2165
178
2276
0.53
7.47
35.4
22.9
39.49
39.21
%
0.23
158
2077
168
2186
0.53
7.46
12.5
10.2
27.56
24.81
u/l
0.37
154
2060
178
2275
0.53
7.44
34.2
22.8
233.40
235.95
e9/l
0.20
166
2176
162
2092
0.56
6.38
25.7
15.8
30.18
28.88
mg/l
0.20
135
1682
176
2220
0.55
6.36
29.6
18.1
139.71
139.59
mmol/l
0.22
163
2129
177
2228
0.56
6.33
29.8
18.2
4.08
4.02
mmol/l
1.81
162
2139
147
1947
0.56
6.29
24.9
15.3
69.86
72.20
ml/min/173m2
0.63
123
1602
33
723
0.40
6.27
2.9
3.3
1.11
0.78
ug/l
0.46
23
505
57
978
0.50
5.55
3.8
4.7
23.20
21.35
%
0.55
31
512
65
1046
0.53
5.07
3.6
4.2
0.00
0.00
estimate
-0.00
15
194
65
1037
0.53
4.88
3.7
4.2
0.00
0.01
estimate
0.80
16
220
65
1030
0.54
4.74
5.3
5.7
0.00
0.00
estimate
-0.00
12
195
160
1990
0.62
4.41
5.2
4.8
2.40
2.69
mmol/l
3.56
142
1710
160
1987
0.62
4.35
4.7
4.8
6.41
6.07
mmol/l
2.13
133
1706
130
1686
0.62
4.20
9.6
7.2
88.36
82.29
u/l
0.75
117
1531
129
1675
0.62
4.18
29.6
18.7
16.11
15.43
%
0.54
122
1630
84
1209
0.59
4.18
4.0
5.7
2.75
3.47
ug/l
0.52
69
1052
154
1911
0.64
3.98
4.7
4.3
4.21
4.55
mmol/l
3.38
139
1669
151
1878
0.64
3.91
4.8
4.3
1.33
1.44
mmol/l
3.09
135
1612
147
1838
0.64
3.89
4.8
4.3
2.19
2.05
mu/l
0.32
125
1584
156
1923
0.64
3.84
6.5
6.1
43.51
40.63
mmol/mol
2.31
141
1708
118
1540
0.64
3.74
4.5
3.9
17.66
14.56
mm/h
0.89
104
1381
51
816
0.56
3.67
3.5
4.5
—
—
—
0
0
150
1815
0.68
2.96
4.4
3.9
1.40
1.26
mmol/l
1.65
134
1536
62
892
0.62
2.83
4.5
3.4
—
—
—
0
0
62
879
0.64
2.62
2.6
2.1
75.33
77.56
nmol/l
0.24
52
736
96
725
1.46
2.40
3.8
2.6
2023.76
1698.53
ng/l
0.37
86
598
46
681
0.62
2.33
4.4
3.4
0.50
0.46
e6/l
0.07
37
526
95
1205
0.70
2.20
2.9
3.0
125.03
54.95
u/l
0.97
80
1094
118
1434
0.72
2.08
4.1
3.6
15.20
15.18
pmol/l
0.02
96
1229
92
1157
0.72
1.98
11.6
8.9
4.96
4.38
e9/l
1.38
79
986
42
606
0.65
1.88
1.8
1.6
14.41
20.56
nmol/l
3.81
35
487
40
580
0.65
1.83
3.2
4.3
0.00
0.00
estimate
-0.00
13
180
92
1136
0.74
1.71
7.1
6.2
11.68
12.39
umol/l
0.31
87
1056
75
956
0.72
1.71
4.5
2.7
—
—
—
0
0
16
83
1.98
1.67
3.1
1.8
213.25
953.47
ug/l
0.73
16
75
26
396
0.63
1.49
4.3
3.3
1.23
1.34
e6/l
0.07
14
239
9
39
2.34
1.44
2.2
1.5
—
—
—
0
0
111
1307
0.77
1.41
6.9
4.0
7.54
6.82
mmol/l
1.27
104
1229
27
397
0.65
1.33
4.1
3.1
0.68
1.15
e6/l
1.05
14
238
75
923
0.76
1.31
2.7
2.4
—
—
—
0
0
83
1007
0.76
1.31
2.0
2.1
93.54
91.29
pmol/l
0.18
48
512
85
1022
0.77
1.24
6.2
4.3
32.94
34.37
g/l
1.44
75
933
51
390
1.36
1.18
6.7
2.8
3016.16
129.29
ng/l
1.00
44
327
39
519
0.72
1.14
4.2
3.4
2.45
2.46
mmol/l
0.18
32
445
102
1172
0.81
0.97
9.7
5.7
1.20
1.21
mmol/l
1.02
81
962
68
815
0.79
0.95
3.3
3.4
2.34
2.34
mmol/l
0.13
58
687
31
232
1.37
0.85
10.1
5.7
0.39
1.26
mmol/l
0.55
21
181
44
543
0.78
0.78
1.7
1.8
354286118.00
13443826.58
pmol/l
0.46
35
424
0
27
0.00
0.78
0.0
1.1
—
414.00
—
0
12
49
402
1.26
0.72
1.8
1.6
2.37
1.47
mg/l
0.66
40
317
7
41
1.72
0.70
1.9
1.5
—
—
—
0
0
46
554
0.80
0.68
3.4
2.7
11392.51
9072.24
umol/l
0.08
39
456
19
258
0.72
0.66
1.3
1.3
26.43
36.48
iu/ml
—
7
86
95
1064
0.85
0.65
8.6
4.9
1.19
1.21
mmol/l
1.36
84
936
67
579
1.20
0.62
2.5
2.1
3.28
3.09
mg/l
0.26
50
478
8
50
1.61
0.61
1.5
1.3
1.11
1.14
g/l
—
8
50
30
237
1.29
0.61
10.3
5.5
4.88
5.19
kpa
1.24
25
224
8
51
1.58
0.61
1.4
1.3
0.26
0.24
g/l
—
8
51
0
22
0.00
0.59
0.0
1.3
—
—
—
0
0
30
238
1.29
0.59
10.3
5.5
11.60
11.59
kpa
0.01
25
227
6
35
1.73
0.58
1.2
1.7
—
—
—
0
0
6
35
1.73
0.58
1.2
1.7
—
—
—
0
0
10
65
1.56
0.56
1.3
1.3
—
—
—
0
0
10
66
1.53
0.53
1.3
1.3
—
—
—
0
0
57
653
0.85
0.52
2.7
2.2
235.50
349.33
u/l
0.43
52
611
8
117
0.68
0.46
1.0
1.3
—
—
—
0
0
26
211
1.25
0.45
5.2
3.2
1.61
1.97
mmol/l
0.21
16
161
0
15
0.00
0.41
0.0
3.3
—
89.25
—
0
15
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
16
124
1.31
0.39
2.1
1.8
—
—
—
0
0
23
279
0.81
0.39
3.0
4.6
8.42
45.02
ug/l
0.77
18
230
14
181
0.76
0.39
1.9
2.0
13.42
12.58
nmol/l
0.10
14
152
20
246
0.80
0.38
1.3
1.3
1.21
17.04
u/ml
—
8
80
18
144
1.26
0.36
4.2
3.9
1.21
1.36
mmol/l
—
9
105
22
265
0.82
0.35
2.8
3.7
—
—
—
0
0
21
173
1.23
0.34
1.6
1.8
—
—
—
0
0
47
418
1.15
0.33
1.9
1.7
—
—
—
0
0
7
99
0.70
0.31
3.3
3.1
—
—
—
0
0
7
54
1.30
0.30
1.1
1.7
—
—
—
0
0
12
150
0.79
0.27
1.6
1.4
—
—
—
0
0
33
294
1.14
0.24
9.0
7.2
—
—
—
0
0
96
908
1.08
0.23
4.8
3.3
276.50
27.64
ng/l
1.70
70
685
5
39
1.29
0.23
2.8
2.9
65.40
61.79
%
—
5
39
5
41
1.22
0.22
1.0
1.7
—
—
—
0
0
0
11
0.00
0.21
0.0
3.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.1
—
—
—
0
0
0
12
0.00
0.21
0.0
1.9
—
—
—
0
0
0
13
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
25
221
1.14
0.21
1.5
2.4
66.66
65.73
g/l
0.28
19
187
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
0
14
0.00
0.20
0.0
1.9
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
64
682
0.92
0.20
3.5
3.8
7.70
9.33
mg/mmol
0.21
46
439
6
50
1.20
0.20
1.5
1.5
—
—
—
0
0
6
50
1.20
0.20
1.5
1.5
—
—
—
0
0
15
175
0.85
0.19
1.5
1.2
—
—
—
0
0
7
58
1.21
0.18
1.1
1.6
—
—
—
0
0
10
82
1.23
0.17
1.3
1.3
—
—
—
0
0
55
580
0.94
0.13
2.0
1.8
1281.80
1171.05
nmol/l
0.36
40
422
30
277
1.09
0.13
3.0
2.1
20.33
23.27
%
0.65
23
235
9
106
0.84
0.13
1.4
2.1
—
—
—
0
0
18
162
1.12
0.12
1.6
1.8
1.47
1.66
%
0.74
18
131
13
114
1.15
0.12
2.4
1.7
—
—
—
0
0
10
86
1.17
0.11
1.3
1.2
—
—
—
0
0
76
788
0.95
0.11
3.3
2.4
132.09
189.64
ug/l
1.78
67
689
49
513
0.95
0.10
3.9
2.6
—
—
—
0
0
5
45
1.11
0.10
2.2
1.4
—
—
—
0
0
5
47
1.06
0.09
1.6
1.4
—
—
—
0
0
17
155
1.10
0.09
2.0
1.5
—
—
—
0
0
10
88
1.14
0.08
1.1
1.1
19.86
145.71
iu/ml
—
5
30
15
163
0.92
0.07
2.3
2.5
62.67
59.19
ml/min/173m2
—
9
64
26
272
0.95
0.05
2.0
1.6
—
—
—
0
0
34
352
0.96
0.04
1.3
1.2
0.66
0.91
u/ml
—
10
83
30
301
1.00
0.00
2.9
2.1
2.18
2.22
g/l
0.14
25
265
28
277
1.01
0.00
2.0
1.6
—
—
—
0
0
116
1157
1.00
0.00
44.0
16.1
1.79
1.37
inr
2.09
33
331
12
115
1.05
0.00
4.3
3.7
44.71
46.58
%
0.09
12
115
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
8.40
—
0
5
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
64.00
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
163.20
—
0
5
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.6
—
923.38
—
0
8
8
84
0.95
-0.00
2.0
1.7
—
—
—
0
0
6
61
0.98
-0.00
1.7
1.8
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint I9_MI_COMPLICATIONS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_MI_COMPLICATIONS | 2.357 [1.88, 2.95] | < 0.001 |
| Birth year | 0.999 [0.99, 1.01] | 0.801 |
During the follow-up period (1.1.1998 — 31.12.2019), 329 out of 499 females with I9_MI_COMPLICATIONS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| I9_MI_COMPLICATIONS | 2.412 [1.98, 2.93] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.006 |
During the follow-up period (1.1.1998 — 31.12.2019), 427 out of 704 males with I9_MI_COMPLICATIONS died.
Mortality risk
Mortality risk for people of age
years, who have I9_MI_COMPLICATIONS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.256% | 0.471% |
| 5 | 1.612% | 2.737% |
| 10 | 4.016% | 6.797% |
| 15 | 7.708% | 13.221% |
| 20 | 13.262% | 21.439% |
Relationships between endpoints
↥Index endpoint: I9_MI_COMPLICATIONS – Complications following myocardial infarction
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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