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Non-seminoma of testis

Endpoint Browser

C3_TESTIS_NONSEMINOMA

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

only males

226754

2. Check conditions

None

226754

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Cause of death: ICD-10 — C62.02&, C62.12&, C62.92&
  • Cause of death: ICD-9 — 186B
  • Cancer registry: Topography ICD-O-3 — C62
  • Cancer registry: Morphology ICD-O-3 — 907[01]|9080|9100
  • Cancer registry: Behaviour codes — 3

2 out of 7 registries used, show all original rules.

100

4. Check minimum number of events

None

100

5. Include endpoints

None

100

6. Filter based on genotype QC (FinnGen only)

98

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF9

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 98 - 98
Unadjusted period prevalence (%) 0.04 - 0.04
Median age at first event (years) 28.58 - 28.58

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
100
Matched controls
1000
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
KFC00
NOMESCO Finland
Unilateral orchiectomy
765.9
81.6
70
*
C62.12
ICD-10 Finland
Malignant tumor of the descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
74.6
62
*
9070/3-C62.9
ICD-O-3
Embryonal carcinoma, NOS, of testis, NOS
+∞
64.8
55
*
A03FA01
ATC
metoclopramide; systemic, rectal
29.1
60.6
49
32
D40.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Testis
310.9
60.5
56
*
130
Kela drug reimbursment
Malignant tumour
+∞
59.4
51
*
JN4BD
NOMESCO Finland
Extensive body CT
28.6
49.9
38
21
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
23.9
22
*
L03AA02
ATC
filgrastim; parenteral
262.5
21.5
21
*
C62.10
ICD-10 Finland
Malignant tumor of the descending testicle, no histological verification
+∞
20.5
19
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
6.7
20.1
65
216
C62.19
ICD-10 Finland
Malignant tumor of the descending testicle, other or undetermined histology
+∞
18.3
17
*
9080/3-C62.9
ICD-O-3
Teratoma, malignant, NOS, of testis, NOS
+∞
18.3
17
*
KFH50
NOMESCO Finland
Insertion of prosthetic replacement for testis
+∞
18.3
17
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
18.3
17
*
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
18.0
17.3
27
20
C62.92
ICD-10 Finland
Malignant tumor in unspecified location in testis, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
17.2
16
*
C62.1
ICD-10 Finland
Malignant neoplasm: Descended testis
+∞
16.1
15
*
H02AB02
ATC
dexamethasone; systemic
46.3
16.0
19
5
Z01.1
ICD-10 Finland
Examination of ears and hearing
6.3
15.3
32
69
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
13.9
13
*
7511
FHL
Orchidectomy (unilateral), also includes funicularectomy
+∞
13.9
13
*
A04AA01
ATC
ondansetron; systemic, rectal
27.0
13.5
18
8
18699
ICD-8 Finland
Malignant neoplasm of testis
+∞
12.8
12
*
JN4AD
NOMESCO Finland
Body CT examination
16.4
12.0
19
14
C62.02
ICD-10 Finland
Malignant tumor of the non-descending testicle, embryonic carsinoma, teratocarcinoma or coriocarsinoma
+∞
11.7
11
*
C62.99
ICD-10 Finland
Malignant tumor in unspecified location in testis,other or undetermined histology
+∞
11.7
11
*
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
+∞
11.7
11
*
9070/3-C62.1
ICD-O-3
Embryonal carcinoma, NOS, of descended testis
+∞
10.6
10
*
9071/3-C62.9
ICD-O-3
Yolk sac tumor, NOS, of testis, NOS
+∞
9.5
9
*
WZC00
NOMESCO Finland
Treatment plan or consultation
3.6
8.6
41
162
C62.11
ICD-10 Finland
Malignant tumor of the descending testicle, seminoma
+∞
8.4
8
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
8.4
8
*
PJD53
NOMESCO Finland
Block dissection of aortic lymph nodes
+∞
8.4
8
*
C62.90
ICD-10 Finland
Malignant tumor in unspecified location in testis, no histological verification
+∞
8.4
8
*
1869B
ICD-9 Finland
Malignant neoplasm of testis, Other and unspecified testis[NEOPL MAL TESTIS (SCROT),CA EMBR/TERATOCA/CHORIOCA]
+∞
8.4
8
*
121
Kela drug reimbursment
Severe hypofunction of sexual glands
36.6
8.2
10
*
ZXE00
NOMESCO Finland
One hour or less
3.4
8.2
43
180
G03BA03
ATC
testosterone; systemic, rectal, sublingual, transdermal
5.2
7.5
17
38
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
7.4
7
*
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
7.1
32
120
JN3AD
NOMESCO Finland
Abdominal CT examination
4.6
7.1
19
49
N45.9
ICD-10 Finland
Orchitis, epididymitis and epididymo-orchitis without abscess
10.5
7.0
13
14
D70.82
ICD-10 Finland
Drug-induced neutropenia
43.1
6.9
8
*
DFF00
NOMESCO Finland
Pure tone audiometry
6.0
6.7
18
35
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
74.4
6.5
7
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
+∞
6.3
6
*
WX402
NOMESCO Finland
General anaesthesia
3.6
6.1
23
76

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
30
14
29.93
22.52
1.1
1.1
—
—
—
0
0
61
238
5.01
14.40
9.2
8.0
1.21
1.20
mmol/l
0.17
49
215
73
383
4.36
10.41
12.1
7.9
3.42
4.13
e9/l
2.38
66
340
30
93
4.18
8.96
1.4
1.5
—
—
—
0
0
42
170
3.54
8.47
1.8
1.4
—
—
—
0
0
37
143
3.52
7.94
2.9
3.2
7.42
7.39
ph
0.87
13
16
34
133
3.36
7.07
1.7
1.5
—
—
—
0
0
35
140
3.31
7.01
7.3
4.2
—
—
—
0
0
34
136
3.27
6.78
1.8
1.6
—
—
—
0
0
61
341
3.02
6.74
6.0
6.9
1.79
1.87
e9/l
0.36
55
308
56
308
2.86
6.23
5.9
6.6
—
—
—
0
0
36
157
3.02
6.13
2.0
2.5
19.93
11.37
e6/l
0.38
24
117
58
329
2.82
6.02
5.8
6.4
0.63
0.57
e9/l
0.88
50
294
58
331
2.79
5.92
5.7
6.3
0.04
0.04
e9/l
0.46
50
296
58
335
2.74
5.72
6.2
7.2
0.16
0.19
e9/l
0.67
50
299
40
193
2.79
5.59
2.1
2.0
—
—
—
0
0
55
312
2.70
5.59
9.5
6.5
0.00
0.00
e9/l
-0.00
44
254
22
75
3.48
5.56
7.1
1.7
2.44
2.41
mmol/l
0.86
22
69
38
182
2.75
5.35
2.3
2.9
13.47
8.85
e6/l
0.23
24
121
31
139
2.78
4.90
2.2
2.5
1.04
0.14
e6/l
0.53
20
102
35
168
2.67
4.84
1.3
1.3
—
—
—
0
0
20
70
3.32
4.83
1.6
1.9
—
—
—
0
0
32
147
2.73
4.82
3.1
2.0
—
—
—
0
0
15
36
4.71
4.76
5.1
1.9
—
—
—
0
0
92
741
4.02
4.64
22.2
9.3
20.99
24.84
mg/l
0.66
78
540
61
388
2.47
4.57
3.9
2.8
—
—
—
0
0
30
139
2.65
4.41
2.2
2.4
—
—
—
0
0
30
152
2.39
3.59
7.9
5.9
—
—
—
0
0
28
141
2.37
3.38
4.0
3.0
—
—
—
0
0
13
45
3.17
3.16
1.0
1.1
—
—
—
0
0
8
16
5.33
3.12
2.8
6.6
—
—
—
0
0
8
16
5.33
3.12
1.4
3.3
—
—
—
0
0
18
76
2.67
3.11
9.6
8.3
104.06
104.21
mmol/l
0.06
18
76
6
8
7.88
3.10
2.7
6.6
4.91
3.68
e9/l
—
6
8
6
8
7.88
3.10
2.8
6.8
61.33
51.88
%
—
6
8
5
5
10.43
3.01
1.0
1.0
—
—
—
0
0
26
136
2.23
2.84
1.3
1.6
2.45
0.67
mg/l
1.52
20
93
40
248
2.02
2.83
13.6
9.1
1.17
1.15
inr
0.08
15
73
5
6
8.68
2.78
1.0
1.0
—
—
—
0
0
12
43
3.03
2.75
4.0
2.2
—
—
—
0
0
10
30
3.59
2.69
6.3
8.1
26.26
24.74
mmol/l
—
10
30
93
814
3.03
2.65
23.0
7.7
—
—
—
0
0
16
72
2.46
2.43
3.8
2.1
10.22
15.34
umol/l
1.89
16
67
7
23
3.19
1.83
23.9
34.7
—
—
—
0
0
41
293
1.68
1.68
2.6
2.5
0.00
0.02
estimate
0.49
13
53
41
295
1.66
1.63
3.6
3.5
0.00
0.00
estimate
-0.00
13
49
6
20
3.12
1.60
1.3
1.6
84.68
216.06
pmol/l
—
6
20
16
87
2.00
1.57
2.5
2.5
—
—
—
0
0
5
15
3.45
1.54
1.4
3.3
—
—
—
0
0
5
15
3.45
1.54
1.4
1.1
—
—
—
0
0
6
22
2.83
1.46
6.2
2.3
—
—
—
0
0
9
43
2.20
1.34
1.0
1.4
—
—
—
0
0
22
141
1.72
1.31
1.2
1.4
2.37
2.42
g/l
0.05
14
98
13
70
1.99
1.31
1.2
1.2
—
—
—
0
0
16
93
1.86
1.30
2.1
1.5
—
—
—
0
0
5
18
2.87
1.30
1.0
1.3
—
—
—
0
0
8
37
2.26
1.24
14.4
13.1
0.55
0.74
%
—
8
37
8
38
2.20
1.21
14.5
12.9
1.38
2.14
%
—
8
38
8
39
2.14
1.18
14.5
12.6
95.09
92.36
%
—
8
39
20
130
1.67
1.14
1.8
2.8
—
—
—
0
0
7
31
2.35
1.13
8.6
3.6
22.23
25.55
mmol/l
—
7
31
39
299
1.50
1.11
2.7
2.5
0.00
0.00
estimate
—
9
42
26
353
0.64
1.10
2.4
2.2
—
—
—
0
0
12
67
1.90
1.10
5.6
3.7
—
—
—
0
0
13
75
1.84
1.09
2.5
2.4
—
—
—
0
0
10
54
1.95
1.00
14.0
9.4
—
—
—
0
0
0
30
0.00
0.99
0.0
5.2
—
—
—
0
0
31
232
1.49
0.98
4.3
2.5
47.52
42.46
ng/l
0.10
23
133
0
32
0.00
0.97
0.0
1.3
—
—
—
0
0
10
57
1.84
0.87
2.1
1.4
—
—
—
0
0
11
65
1.78
0.86
6.0
3.5
2.63
2.04
mmol/l
0.39
11
58
6
32
1.93
0.83
1.3
1.2
—
54.00
—
0
5
11
66
1.75
0.82
1.4
2.0
—
—
—
0
0
8
48
1.72
0.81
5.9
3.5
131.13
137.44
g/l
—
8
48
25
186
1.46
0.81
2.4
1.6
99.65
90.10
pmol/l
0.53
15
102
20
142
1.51
0.80
2.8
3.8
14.39
98.05
mg/l
1.91
13
101
0
26
0.00
0.79
0.0
1.2
—
—
—
0
0
5
23
2.23
0.77
2.0
4.1
—
—
—
0
0
20
144
1.49
0.75
3.3
2.6
0.17
0.02
estimate
0.39
12
48
21
153
1.47
0.75
3.2
4.4
13.13
13.45
mg/mmol
0.01
15
108
5
25
2.05
0.74
1.0
1.0
—
—
—
0
0
22
163
1.45
0.72
3.1
2.1
—
—
—
0
0
52
450
1.32
0.66
4.1
3.0
—
—
—
0
0
16
116
1.45
0.59
4.2
3.0
950.73
507.74
ng/l
0.18
11
89
69
747
0.75
0.58
3.2
3.2
1.56
1.39
mmol/l
0.80
64
714
6
37
1.66
0.56
11.0
17.8
—
—
—
0
0
7
48
1.49
0.48
1.0
1.3
—
—
—
0
0
5
33
1.54
0.42
1.4
1.2
—
—
—
0
0
0
15
0.00
0.41
0.0
1.1
—
14.54
—
0
8
0
17
0.00
0.41
0.0
11.5
—
1314.53
—
0
17
19
152
1.31
0.41
1.1
1.3
0.47
1.40
u/ml
—
6
45
0
18
0.00
0.40
0.0
1.1
—
—
—
0
0
24
199
1.27
0.40
2.9
3.2
9.73
9.59
mmol/l
0.04
19
181
0
19
0.00
0.39
0.0
3.3
—
0.24
—
0
13
6
42
1.46
0.36
3.5
2.4
0.52
0.57
%
—
6
42
6
42
1.46
0.36
1.2
1.2
—
—
—
0
0
6
42
1.46
0.36
3.5
2.4
1.77
1.92
%
—
6
42
37
327
1.21
0.35
4.2
3.0
1.45
1.54
ug/l
0.12
32
297
6
46
1.32
0.33
1.7
2.7
—
—
—
0
0
7
93
0.73
0.23
2.7
1.8
—
—
—
0
0
7
94
0.73
0.23
2.7
1.6
—
—
—
0
0
7
94
0.73
0.23
2.7
1.8
—
—
—
0
0
7
94
0.73
0.23
2.7
1.8
—
—
—
0
0
5
40
1.26
0.23
1.2
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
8.0
—
0.52
—
0
11
0
10
0.00
0.21
0.0
1.3
—
86.70
—
0
10
6
47
1.29
0.21
1.3
1.3
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
11.24
—
0
5
13
153
0.83
0.19
1.2
1.3
—
—
—
0
0
5
67
0.73
0.17
2.6
1.9
—
—
—
0
0
7
89
0.77
0.15
2.7
1.9
—
—
—
0
0
5
63
0.78
0.08
4.2
2.2
—
—
—
0
0
7
68
1.03
0.08
2.7
2.1
—
—
—
0
0
14
139
1.01
0.00
1.4
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
40.33
—
0
7
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
11.60
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1016.00
—
0
5
0
5
0.00
-0.00
0.0
4.0
—
0.80
—
0
5
0
5
0.00
-0.00
0.0
4.2
—
70.40
—
0
5
0
6
0.00
-0.00
0.0
1.3
—
1.55
—
0
6
0
8
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
406.33
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: C3_TESTIS_NONSEMINOMA – Non-seminoma of testis

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).