age-related macular degeneration: Age-related loss of vision in the central portion of the retina (macula), secondary to retinal degeneration.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
519972 |
1. Apply sex-specific ruleNone |
519972 |
2. Check conditionsNone |
519972 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1040 |
4. Check minimum number of eventsNone |
1040 |
5. Include endpointsNone |
1040 |
6. Filter based on genotype QC (FinnGen only) |
996 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 5
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- H35
Similar endpoints
↥List of similar endpoints to
Macular cyst
based on the number of shared cases.
Similar with more cases:
- Degeneration of macula and posterior pole
- Other retinal disorders
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3939 | 2208 | 1725 |
| Only index persons | 3877 | 2177 | 1700 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.06 | 0.05 |
| Only index persons | 0.07 | 0.08 | 0.06 |
| Median age at first event (years) | |||
| Whole population | 72.17 | 72.28 | 72.05 |
| Only index persons | 72.18 | 72.31 | 72.02 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 996 | 551 | 445 |
| Unadjusted period prevalence (%) | 0.20 | 0.20 | 0.20 |
| Median age at first event (years) | 72.60 | 71.85 | 73.53 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1040
- Matched controls
- 10400
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z96.1
ICD-10 Finland
Presence of intraocular lens
11.5
307.7
545
907
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
291.1
307.7
322
16
WX140
NOMESCO Finland
Parabulbar anesthesy
50.7
307.7
361
108
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
426.0
307.7
343
12
H35.36
ICD-10 Finland
Macular cyst
+∞
307.7
1035
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
26.8
307.7
525
381
XCW99
NOMESCO Finland
Other investigative procedure of eye
14.4
307.7
390
415
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
17.3
298.5
273
210
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
385.9
245.4
238
8
CKC12
NOMESCO Finland
Photocoagulation of retina
112.8
216.7
111
11
Z01.0
ICD-10 Finland
Examination of eyes and vision
6.5
184.4
429
1020
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
6.0
169.2
716
2814
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
63.0
165.4
92
16
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
219.1
164.2
166
9
S01ED51
ATC
timolol, combinations; ophthalmic
7.6
157.7
264
446
WX100
NOMESCO Finland
Conjunctival surface anesthesia
5.6
145.1
370
932
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
23.5
141.2
104
49
XCD20
NOMESCO Finland
Photoangiography of eye
74.5
140.5
76
11
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
321.1
140.1
139
5
XCK10
NOMESCO Finland
Photography of fundus of eye
6.6
130.9
247
467
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
367.8
129.6
128
*
H25.1
ICD-10 Finland
Senile nuclear cataract
4.4
124.6
594
2396
H20.1
ICD-10 Finland
Chronic iridocyclitis
44.8
119.0
71
17
H33.0
ICD-10 Finland
Retinal detachment with retinal break
1252.3
117.1
112
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
9.4
102.9
130
155
H26.4
ICD-10 Finland
After-cataract
5.2
100.1
248
593
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic
3.7
94.7
589
2709
XCH00
NOMESCO Finland
Eye pressure measurement
7.9
94.5
139
199
S01EC01
ATC
acetazolamide; systemic
13.6
93.4
90
72
CJB10
NOMESCO Finland
Laser discission of secondary cataract
5.4
92.0
212
474
ZXA10
NOMESCO Finland
Bilateral
3.9
89.5
368
1281
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
923.0
88.0
85
*
S01EC04
ATC
brinzolamide; ophthalmic
7.0
86.2
143
233
WX002
NOMESCO Finland
Sedation and analgesia
3.7
83.7
381
1411
H35.37
ICD-10 Finland
Macular holes
852.3
81.6
79
*
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
+∞
80.3
76
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
388.8
73.7
73
*
S01EA03
ATC
apraclonidine; ophthalmic
26.8
73.6
51
20
XCK00
NOMESCO Finland
Perimetry
5.7
73.0
150
300
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
383.0
72.6
72
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
713.5
68.8
67
*
CK2M4
NOMESCO Finland
Macular light layer imaging (OCT)
34.5
67.3
43
13
S01ED01
ATC
timolol; ophthalmic
7.1
66.2
105
162
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
5.1
63.1
146
323
ZXA05
NOMESCO Finland
Left side
2.9
59.4
417
1930
H43.1
ICD-10 Finland
Vitreous haemorrhage
14.7
57.4
52
37
S01BC03
ATC
diclofenac; ophthalmic
9.4
57.2
70
79
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
578.0
56.1
55
*
S01EC54
ATC
brinzolamide, combinations; ophthalmic
11.5
55.9
59
54
S01EA05
ATC
brimonidine; ophthalmic
7.5
55.3
82
117
114
Kela drug reimbursment
Glaucoma
3.8
54.9
193
586
H34.8
ICD-10 Finland
Other retinal vascular occlusions
193.3
53.5
55
*
S01EE01
ATC
latanoprost; ophthalmic
4.3
53.2
152
397
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
51.5
49
*
XCW10
NOMESCO Finland
Assessment of vision
14.0
50.5
47
35
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.6
50.4
604
3584
H33.3
ICD-10 Finland
Retinal breaks without detachment
256.8
48.5
49
*
ZXA00
NOMESCO Finland
Right side
2.6
48.3
421
2132
H35.8
ICD-10 Finland
Other specified retinal disorders
+∞
47.2
45
*
H26.2
ICD-10 Finland
Complicated cataract
15.4
45.3
40
27
CKD60
NOMESCO Finland
Anterior vitrectomy
14.1
45.3
42
31
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
45.1
43
*
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
5.7
44.5
86
161
XCH05
NOMESCO Finland
Eye pressure longterm registration
12.2
39.6
40
34
H36.01
ICD-10 Finland
Diabetic maculopathy
109.3
39.0
42
*
Z3231
NOMESCO Finland
Registered nurse
2.4
38.7
385
2031
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
4.3
38.2
107
273
S01EC03
ATC
dorzolamide; ophthalmic
9.2
37.4
46
52
H40.0
ICD-10 Finland
Glaucoma suspect
3.4
36.8
147
479
H3601, E113,
ICD-10 Finland
+∞
36.7
35
*
Z2221
NOMESCO Finland
Medical doctor
2.3
34.5
360
1920
S01EE03
ATC
bimatoprost; ophthalmic
5.7
34.5
66
122
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
12.1
32.6
33
28
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
31.4
30
*
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
311.1
30.0
30
*
ZXD10
NOMESCO Finland
Scheduled procedure
2.1
29.4
479
3009
ZXE00
NOMESCO Finland
One hour or less
2.0
26.7
458
2904
S01EE05
ATC
tafluprost; ophthalmic
4.0
26.6
79
210
Z3229
NOMESCO Finland
Other healthcare associate professional
2.9
25.7
132
495
CHC05
NOMESCO Finland
Iridotomy
6.5
25.4
42
67
WX142
NOMESCO Finland
Sub-tenon anesthesy
26.2
24.1
33
13
CJ2M4
NOMESCO Finland
Scans and measurement printouts for intraocular lens power calculation
7.9
23.9
33
43
CHD05
NOMESCO Finland
Selective lasertrabeculoplasty
3.8
23.8
74
203
H40.10
ICD-10 Finland
Capsular glaucoma with pseudoexfoliation on the anterior lens capsule
4.3
23.8
64
158
S01EE04
ATC
travoprost; ophthalmic
5.3
23.5
48
94
CS2P4
NOMESCO Finland
Optic nerve head imaging
9.0
23.4
29
33
T85.2
ICD-10 Finland
Mechanical complication of intraocular lens
25.3
23.2
32
13
H43.8
ICD-10 Finland
Other disorders of vitreous body
2.7
23.1
140
572
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
7.5
23.0
33
45
H25.8
ICD-10 Finland
Other senile cataract
2.4
22.9
176
805
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
23.5
22.7
32
14
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
8.7
22.0
28
33
CS494
NOMESCO Finland
Other visual field testing
4.6
21.9
53
120
H35.9
ICD-10 Finland
Retinal disorder, unspecified
51.1
21.2
25
5
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
8.9
20.7
26
30
F38
ICPC
Eye, Other laboratory test NEC
6.5
20.6
34
54
A10AA01, ,
ATC
7.6
20.4
29
39
CJF45
NOMESCO Finland
Removal and implantation of artificial lens in anterior chamber with iridectomy or iridotomy
49.0
20.2
24
5
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
19.9
19
*
H3600, E113,
ICD-10 Finland
+∞
19.9
19
*
F29
ICPC
Eye symptom/complaint other
2.6
19.7
129
546
H27.1
ICD-10 Finland
Dislocation of lens
19.8
19.6
29
15
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
40.9
19.6
24
6
A10AB01
ATC
insulin (human); parenteral
5.9
19.4
35
61
A10AA02, ,
ATC
5.5
18.2
35
65
H26.02
ICD-10 Finland
Presenil cataract
4.4
18.0
45
105
H33.5
ICD-10 Finland
Other retinal detachments
27.2
17.9
24
9
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
96.7
17.6
19
*
Z71.8
ICD-10 Finland
Other specified counselling
1.9
17.6
327
2064
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
183.0
17.6
18
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
17.3
414
2816
A98
ICPC
Health maint/preventive medicine
5.0
17.3
1015
9261
A10AC01
ATC
insulin (human); parenteral
2.8
16.9
88
331
H53.1
ICD-10 Finland
Subjective visual disturbances
2.8
16.9
88
331
CG2T4
NOMESCO Finland
Topography assessment of cornea
7.4
16.6
24
33
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
172.7
16.5
17
*
H20.8
ICD-10 Finland
Other iridocyclitis
23.5
16.5
23
10
CKC10
NOMESCO Finland
Local photocoagulation of retina
48.3
16.1
19
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
4.4
16.0
40
93
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.8
16.0
307
1947
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
3.3
15.9
60
187
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
4.4
15.6
39
91
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
38.7
15.4
19
5
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
16.3
15.3
24
15
CS3P4
NOMESCO Finland
Optic nerve head stereophotography
6.2
15.2
26
43
A10AB04
ATC
insulin lispro; parenteral
4.7
15.0
35
77
S01BC05
ATC
ketorolac; ophthalmic
3.2
14.9
59
190
H25.0
ICD-10 Finland
Senile incipient cataract
2.5
14.7
94
392
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
+∞
14.6
14
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
14.6
14
*
CS5Z4
NOMESCO Finland
Specialised imaging for glaucoma
4.0
14.6
42
109
H36.00
ICD-10 Finland
Diabetic background retinopathy
81.3
14.6
16
*
CS434
NOMESCO Finland
Visual field testing with Humphrey automated perimetry
4.0
14.3
41
106
R4110
NOMESCO Finland
Physiotherapy
1.7
14.1
324
2153
H53.9
ICD-10 Finland
Visual disturbance, unspecified
3.5
13.9
47
137
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
15.0
13.6
22
15
1LA05, ,
NOMESCO Finland
+∞
13.6
13
*
H3601, E103,
ICD-10 Finland
+∞
13.6
13
*
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.0
13.5
38
97
CHD65
NOMESCO Finland
Nonpenetrating glaucoma surgery
9.8
13.3
26
27
H04.10
ICD-10 Finland
Dry eye syndrome
2.1
13.1
127
634
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
50.7
12.9
15
*
CHF05
NOMESCO Finland
Transscleral laser coagulation of ciliary body
17.6
12.5
19
11
H3603, E103,
ICD-10 Finland
+∞
12.5
12
*
H3600, E103,
ICD-10 Finland
+∞
12.5
12
*
H16.0
ICD-10 Finland
Corneal ulcer
2.8
12.2
60
219
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic
5.4
11.9
23
43
CFW99
NOMESCO Finland
Other operation on conjunctiva
19.2
11.6
17
9
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
11.5
11
*
H3603, E113,
ICD-10 Finland
+∞
11.5
11
*
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
3.5
11.5
40
119
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
121.3
11.4
12
*
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
12.0
11.4
20
17
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
8.4
11.3
24
29
ZX198
NOMESCO Finland
Other local administration
12.9
11.2
19
15
T89
ICPC
Diabetes insulin dependent
3.5
10.8
36
104
H35.6
ICD-10 Finland
Retinal haemorrhage
+∞
10.4
10
*
H57.1
ICD-10 Finland
Ocular pain
3.1
10.3
42
138
H18.2
ICD-10 Finland
Other corneal oedema
23.6
10.3
14
6
A10AB05
ATC
insulin aspart; parenteral
2.3
10.2
80
367
H44.0
ICD-10 Finland
Purulent endophthalmitis
40.5
10.0
12
*
A10AE04
ATC
insulin glargine; parenteral
2.1
9.9
102
520
A10AE05
ATC
insulin detemir; parenteral
2.6
9.9
57
226
CJF00
NOMESCO Finland
Secondary implantation of artificial lens in anterior chamber
55.5
9.7
11
*
S01BA04
ATC
prednisolone; ophthalmic
3.6
9.6
31
88
Z3226
NOMESCO Finland
Physiotherapist
1.7
9.4
203
1307
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
9.4
9
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
9.4
9
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
9.4
9
*
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
21.9
9.4
13
6
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
21.9
9.4
13
6
WX110
NOMESCO Finland
Infiltration anesthesia
1.5
9.3
678
5732
L17
ICPC
Foot/toe symptom/complaint
1.6
9.2
308
2208
S01EX03, ,
ATC
3.8
9.2
28
76
H40
ICD-10 Finland
Glaucoma
4.8
9.1
20
42
CKA10
NOMESCO Finland
Biopsy of vitreous body
37.0
9.0
11
*
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
18.8
8.9
13
7
CHD15
NOMESCO Finland
Trabeculectomy and iridectomy
8.0
8.9
19
24
CH2X4
NOMESCO Finland
Optical coherence tomography (OCT) of iris and iridocorneal angle
50.4
8.7
10
*
H35.4
ICD-10 Finland
Peripheral retinal degeneration
50.4
8.7
10
*
CHD99
NOMESCO Finland
Other filtering operation
11.7
8.6
15
13
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
27.8
8.5
11
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
8.3
8
*
SDA03
NOMESCO Finland
Periodontal treatment
1.5
8.3
353
2652
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
3.7
8.2
25
68
ZXD20
NOMESCO Finland
Day surgery
1.8
8.1
133
792
H26.3
ICD-10 Finland
Drug-induced cataract
8.2
8.1
17
21
CJG15
NOMESCO Finland
Extraction of dislocated lens with implantation of artificial lens in anterior chamber and iridectomy or iridotomy
22.2
8.0
11
5
R23.8
ICD-10 Finland
Other and unspecified skin changes
1.6
8.0
206
1384
CHD35
NOMESCO Finland
Laser goniopuncture
7.8
7.9
17
22
CHD00
NOMESCO Finland
Laser trabeculoplasty
4.1
7.8
21
52
CG2S4
NOMESCO Finland
Photography of cornea
9.5
7.8
15
16
Z01.7
ICD-10 Finland
Laboratory examination
1.7
7.7
151
945
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
45.3
7.7
9
*
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
7.5
7.7
17
23
U02
ICPC
Urinary frequency/urgency
1.7
7.7
158
1002
E10
ICD-10 Finland
Type 1 diabetes mellitus
7.2
7.5
17
24
ZXC20
NOMESCO Finland
Use of chemical agents
3.0
7.5
33
114
L04AB04
ATC
adalimumab; parenteral
3.9
7.5
21
54
H21.0
ICD-10 Finland
Hyphaema
11.0
7.3
13
12
H34.9
ICD-10 Finland
Retinal vascular occlusion, unspecified
+∞
7.3
7
*
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
7.3
7
*
D06
ICPC
Abdominal pain localized other
1.9
7.2
85
456
H26.8
ICD-10 Finland
Other specified cataract
4.4
7.0
17
39
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
6.9
92
515
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.8
206
1433
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
16.8
6.7
10
6
R05
ICD-10 Finland
Cough
1.5
6.7
207
1446
Z71.9
ICD-10 Finland
Counselling, unspecified
2.0
6.7
70
360
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
6.7
399
3170
H01.0
ICD-10 Finland
Blepharitis
2.1
6.6
59
286
Z01.2
ICD-10 Finland
Dental examination
1.4
6.6
391
3102
D19
ICPC
Teeth/gum symptom/complaint
1.5
6.6
242
1755
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.1
6.5
62
309
J01DB01
ATC
cefalexin; oral
1.5
6.4
805
7260
EB1AA, ,
SPAT
2.0
6.4
65
332
CD2S4
NOMESCO Finland
Photography of eye
6.6
6.3
15
23
N17
ICPC
Vertigo/dizziness
1.6
6.3
135
863
S01FA02
ATC
scopolamine; ophthalmic
5.6
6.3
17
31
H04AA01
ATC
glucagon; nasal, parenteral
5.6
6.3
17
31
CKC70
NOMESCO Finland
Circular buckling of sclera
+∞
6.3
6
*
CKC20
NOMESCO Finland
Cryopexy of undetached retina
+∞
6.3
6
*
H34.1
ICD-10 Finland
Central retinal artery occlusion
+∞
6.3
6
*
G44.2
ICD-10 Finland
Tension-type headache
1.7
6.2
122
763
H33
ICD-10 Finland
Retinal detachments and breaks
26.8
6.2
8
*
H40.9
ICD-10 Finland
Glaucoma, unspecified
3.0
6.2
27
93
L02
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle
2.5
6.2
37
151
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
5.8
6.2
16
28
H52.1
ICD-10 Finland
Myopia
3.0
6.1
26
88
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.1
236
1725
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
12.6
6.1
10
8
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
2.9
6.1
27
94
K03.64
ICD-10 Finland
Dental calculus supragingival
1.5
6.0
254
1887
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
291
1664
2.04
21.71
3.2
2.9
1.13
1.35
e6/l
0.34
156
976
275
1553
2.05
21.16
3.3
3.1
2.65
2.42
e6/l
0.15
141
869
100
365
2.92
20.37
2.5
1.9
38.18
38.92
u/l
0.14
93
320
951
8259
2.77
19.83
17.2
15.5
72.35
75.18
ml/min/173m2
3.86
781
6820
926
7979
2.46
18.96
5.3
4.8
4.27
2.17
mu/l
0.45
847
7169
1014
9177
5.20
18.95
21.6
19.4
3.97
3.99
mmol/l
1.43
995
8919
1015
9194
5.33
18.92
12.6
11.3
24.06
24.83
u/l
1.10
982
8822
1012
9157
4.91
18.68
21.3
19.2
139.96
139.67
mmol/l
3.11
993
8910
471
3294
1.79
18.16
4.3
4.0
82.11
104.58
e6/l
0.36
319
2392
1029
9455
9.35
18.11
26.7
24.1
133.78
133.46
g/l
0.29
1016
9291
400
2669
1.81
18.04
3.6
3.4
0.39
0.47
e6/l
0.39
289
2046
982
8758
3.17
17.79
6.0
5.4
2.58
2.66
mmol/l
2.22
895
7930
1028
9451
8.60
17.78
26.6
23.9
6.70
6.73
e9/l
0.16
987
9151
1028
9454
8.57
17.70
26.6
23.9
241.31
245.00
e9/l
1.21
991
9185
1028
9455
8.56
17.68
26.6
23.9
4.43
4.42
e12/l
0.35
987
9152
1027
9452
7.92
17.33
26.9
24.1
39.94
39.56
%
1.13
981
8737
864
7319
2.07
17.17
22.2
19.5
14.61
15.37
%
4.24
852
7184
546
4033
1.74
17.01
2.1
2.1
95.44
94.51
pmol/l
0.17
256
2019
123
548
2.41
16.77
2.5
2.6
20.34
25.72
au/ml
—
5
29
964
8605
2.65
15.73
5.4
5.0
6.18
6.02
mmol/l
2.84
871
7719
411
2874
1.71
15.05
3.6
3.5
47.49
87.99
e6/l
0.85
301
2230
947
8487
2.30
13.53
5.1
4.7
1.51
1.47
mmol/l
1.55
865
7679
926
8228
2.14
13.49
7.2
6.2
41.27
40.24
mmol/mol
2.31
859
7514
30
64
4.80
13.36
1.0
1.1
—
—
—
0
0
951
8549
2.31
13.29
5.1
4.7
4.54
4.57
mmol/l
0.42
875
7785
779
6591
1.72
12.77
4.2
4.0
14.96
15.06
pmol/l
0.46
696
5890
820
7055
1.77
12.46
7.9
7.9
82.54
79.48
u/l
0.62
761
6612
724
6051
1.65
11.97
5.4
4.9
—
2522.41
—
0
92
780
6647
1.69
11.93
4.8
4.2
13.94
13.83
mm/h
0.07
712
6086
951
8634
2.19
11.54
17.8
16.2
25.82
25.61
mg/l
0.06
764
6954
483
3688
1.58
11.53
2.5
2.2
79.00
79.93
nmol/l
0.29
424
3229
597
4813
1.56
11.04
8.2
7.1
1.21
1.21
mmol/l
0.66
543
4086
22
43
5.21
10.82
2.0
2.7
687.68
1239.47
u/ml
1.02
22
43
537
4257
1.54
10.49
7.2
5.9
27.04
26.81
%
0.19
495
3965
631
5196
1.55
10.26
9.2
9.2
4.09
4.13
e9/l
0.18
532
4537
529
4193
1.53
10.25
7.1
5.7
57.42
57.82
%
0.33
489
3902
269
1832
1.63
10.12
4.0
4.1
927.61
353.42
ng/l
0.74
240
1543
147
851
1.85
9.89
2.7
2.4
31.14
41.05
u/l
1.03
125
733
337
2446
1.56
9.61
1.6
1.7
1.30
1.34
mmol/l
0.39
290
2045
550
4440
1.51
9.49
6.8
6.2
1.21
1.21
mmol/l
0.63
511
4027
903
8205
1.76
8.74
4.5
4.2
1.30
1.28
mmol/l
0.28
809
7351
56
235
2.46
8.70
1.6
1.6
—
—
—
0
0
59
256
2.38
8.53
1.7
1.6
0.15
0.10
iu/ml
0.22
15
45
528
4315
1.45
8.03
2.5
2.4
—
—
—
0
0
49
202
2.50
7.93
1.5
1.2
—
—
—
0
0
111
646
1.80
7.31
1.7
1.6
—
—
—
0
0
323
2436
1.47
7.30
2.9
2.8
5091.55
7399.09
umol/l
0.42
277
2101
524
4353
1.41
6.87
4.1
4.0
0.00
0.00
estimate
0.75
78
899
251
1838
1.48
6.47
3.1
3.2
0.76
0.80
ug/l
0.29
192
1288
526
4407
1.39
6.38
4.2
4.0
0.00
0.01
estimate
0.80
69
819
150
990
1.60
6.20
2.5
2.7
10.72
8.28
umol/l
0.53
129
870
520
4368
1.38
6.11
6.0
5.4
0.00
0.00
estimate
0.50
68
836
365
2904
1.40
5.90
2.1
2.1
145.20
245.49
u/l
2.45
339
2727
16
44
3.68
5.21
1.1
1.2
—
—
—
0
0
382
3139
1.34
4.82
4.4
3.7
22.36
8.02
mg/mmol
2.26
242
1949
361
2951
1.34
4.69
3.9
3.2
448.89
282.03
mg/l
0.28
228
1864
368
3020
1.34
4.65
3.7
3.1
6.92
7.21
mmol/l
0.74
306
2510
38
179
2.17
4.65
1.4
1.4
—
—
—
0
0
419
3506
1.33
4.62
3.2
2.8
151.67
143.78
ug/l
0.22
382
3173
248
1917
1.39
4.59
3.2
3.1
2.46
2.47
mmol/l
0.06
210
1689
118
794
1.55
4.48
5.5
3.8
113.17
91.68
ng/l
1.16
105
689
242
1873
1.38
4.43
1.6
1.7
1.21
1.28
mg/l
0.15
184
1461
559
4891
1.31
4.39
5.5
6.6
12.06
11.46
umol/l
0.43
538
4665
38
185
2.09
4.30
1.3
1.1
—
—
—
0
0
259
2037
1.36
4.27
2.6
2.7
4.02
5.36
e6/l
1.82
233
1830
98
641
1.58
4.22
8.0
9.5
94.65
94.00
%
1.14
98
635
42
216
1.98
4.11
1.2
1.4
—
—
—
0
0
42
216
1.98
4.11
1.2
1.4
—
—
—
0
0
74
459
1.66
3.95
3.0
3.1
4.15
4.39
pmol/l
1.64
62
397
9
16
5.66
3.66
1.0
1.0
—
—
—
0
0
188
1438
1.38
3.66
1.3
1.3
16.56
39.69
iu/ml
5.68
57
471
47
263
1.82
3.61
1.1
1.1
—
—
—
0
0
53
308
1.76
3.60
1.3
1.6
—
172.31
—
0
13
47
266
1.80
3.49
1.1
1.1
—
—
—
0
0
609
5480
1.27
3.47
5.5
5.0
7.04
6.76
mmol/l
2.37
567
5175
293
2410
1.30
3.47
1.6
1.6
21.94
20.87
nmol/l
0.57
260
2016
213
1675
1.34
3.46
1.2
1.2
1.93
1.34
u/ml
0.18
46
434
125
903
1.44
3.38
6.5
3.7
0.75
2.10
mmol/l
2.79
106
762
28
134
2.12
3.36
1.1
1.1
—
—
—
0
0
172
1316
1.37
3.34
3.4
2.6
22.32
22.21
%
0.04
152
1122
156
1178
1.38
3.28
6.8
7.7
5.07
5.11
kpa
0.22
146
1124
156
1179
1.38
3.26
6.8
7.7
12.64
11.91
kpa
0.97
145
1126
16
60
2.69
3.23
1.3
1.1
—
—
—
0
0
16
60
2.69
3.23
1.3
1.1
—
—
—
0
0
372
3181
1.26
3.19
5.7
5.4
2.68
2.86
ug/l
0.19
332
2822
178
1380
1.35
3.17
3.3
2.5
2.16
2.28
g/l
2.56
167
1279
152
1151
1.38
3.14
1.8
1.9
—
—
—
0
0
13
40
3.28
3.14
1.4
1.3
—
—
—
0
0
16
61
2.65
3.14
1.3
1.1
—
—
—
0
0
16
61
2.65
3.14
1.3
1.1
—
—
—
0
0
16
61
2.65
3.14
1.3
1.1
—
—
—
0
0
584
5271
1.25
3.07
3.1
3.2
52.95
52.20
u/l
0.06
537
4826
151
1147
1.37
3.07
1.8
1.8
—
—
—
0
0
474
4190
1.24
2.98
5.1
4.9
35.51
34.94
g/l
1.53
445
3893
22
101
2.20
2.94
1.2
1.1
—
—
—
0
0
22
101
2.20
2.94
2.3
3.6
55.35
56.92
%
0.12
17
85
189
1497
1.32
2.91
3.3
2.6
12.39
12.43
umol/l
0.02
177
1405
9
22
4.12
2.88
1.0
1.1
1092.78
1632.00
miu/ml
—
9
22
7
13
5.41
2.87
10.1
11.4
4.79
5.88
mmol/l
—
7
13
154
1187
1.35
2.85
6.8
7.7
0.82
1.24
mmol/l
0.72
129
947
134
1016
1.37
2.76
1.2
1.3
—
—
—
0
0
379
3299
1.23
2.67
3.8
3.6
2.36
2.36
mmol/l
0.54
320
2860
149
1156
1.34
2.65
3.4
4.1
238.95
252.46
u/l
0.66
144
1084
165
1301
1.32
2.62
8.9
5.7
1.06
1.02
mmol/l
1.05
149
1191
302
2571
1.25
2.60
4.3
4.6
22.47
21.44
%
0.60
159
1315
56
363
1.57
2.59
1.2
1.2
—
—
—
0
0
355
3078
1.23
2.58
3.0
3.1
1559.12
1430.70
ng/l
0.22
303
2637
271
2283
1.25
2.56
2.3
2.4
—
—
—
0
0
203
1654
1.28
2.53
1.8
1.9
—
—
—
0
0
71
495
1.47
2.37
1.7
1.8
1.58
1.63
g/l
0.19
65
432
10
33
3.05
2.36
1.1
1.1
—
—
—
0
0
16
71
2.27
2.35
1.6
1.4
—
—
—
0
0
117
893
1.35
2.33
2.0
2.1
231.12
149.12
ug/g
0.49
92
709
9
28
3.23
2.31
1.9
2.5
39.78
13.21
ug/l
—
9
22
38
231
1.67
2.29
1.6
1.8
2.65
3.15
mg/l
0.20
23
188
192
1574
1.27
2.27
3.2
3.3
0.83
0.81
mmol/l
1.27
169
1468
12
47
2.57
2.27
1.3
1.1
—
—
—
0
0
41
256
1.63
2.24
1.5
1.7
16201.38
14628.18
e6/l
0.10
32
182
5
9
5.58
2.21
1.0
1.0
—
—
—
0
0
5
9
5.58
2.21
3.6
6.2
—
—
—
0
0
317
2757
1.22
2.18
3.2
3.4
33.19
32.37
u/l
0.09
288
2618
23
122
1.91
2.17
1.3
1.3
49.11
28.01
iu/l
1.11
18
102
135
1068
1.30
2.11
6.8
8.1
96.14
95.52
%
0.89
129
1028
21
109
1.95
2.11
1.1
1.4
—
—
—
0
0
35
214
1.66
2.09
1.7
1.7
—
—
—
0
0
5
10
5.02
2.07
1.2
1.2
—
—
—
0
0
7
20
3.52
2.05
1.3
1.3
—
—
—
0
0
59
411
1.46
2.01
2.4
2.9
3.53
3.64
g/l
0.33
50
374
77
564
1.39
2.00
2.1
2.1
11.31
12.36
nmol/l
0.48
66
493
94
712
1.35
1.99
1.5
1.6
—
—
—
0
0
62
437
1.45
1.99
1.8
1.7
—
—
—
0
0
59
412
1.46
1.99
2.4
2.9
7.59
7.50
g/l
0.16
51
374
59
412
1.46
1.99
2.4
2.9
—
—
—
0
0
57
397
1.46
1.95
2.4
2.9
9.53
10.43
g/l
0.92
48
358
55
381
1.47
1.94
2.5
2.9
2.99
3.04
g/l
0.12
47
344
18
92
1.97
1.91
2.0
2.2
—
—
—
0
0
36
228
1.60
1.89
2.4
2.2
195.31
87.00
ug/min
0.53
16
140
(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay
53
368
1.46
1.85
3.5
2.6
0.25
0.37
u/ml
3.50
25
207
144
1170
1.27
1.85
2.4
2.4
1.62
1.81
%
2.32
125
1042
46
311
1.50
1.83
2.3
2.9
0.22
0.06
g/l
0.37
39
289
44
295
1.51
1.82
2.4
2.9
0.00
0.00
g/l
-0.00
37
276
5
12
4.18
1.82
1.6
1.2
—
—
—
0
0
276
2408
1.20
1.81
2.3
2.2
2.97
3.06
mg/l
0.24
224
2021
44
298
1.50
1.75
2.4
2.9
0.00
0.00
g/l
-0.00
37
277
0
47
0.00
1.70
0.0
3.9
—
—
—
0
0
50
355
1.43
1.59
1.1
1.0
—
—
—
0
0
47
333
1.43
1.52
2.3
2.7
37.41
37.25
g/l
0.06
38
296
11
51
2.17
1.51
1.3
1.5
—
391.25
—
0
8
109
880
1.27
1.50
3.1
3.0
65.35
66.24
g/l
0.62
96
803
25
155
1.63
1.48
1.2
1.2
—
—
—
0
0
49
353
1.41
1.46
2.3
3.1
0.80
1.51
g/l
0.66
40
311
18
103
1.76
1.41
1.2
1.3
241.00
291.71
pmol/l
0.45
13
89
222
1947
1.18
1.36
1.7
1.7
959.50
1164.33
nmol/l
2.98
154
1444
180
2077
0.84
1.36
1.6
1.7
442.84
17233587.59
pmol/l
1.21
144
1677
0
38
0.00
1.34
0.0
3.1
—
—
—
0
0
0
38
0.00
1.34
0.0
3.1
—
—
—
0
0
91
730
1.27
1.34
3.4
3.0
50.60
61.05
ml/min/173m2
2.24
30
312
40
284
1.42
1.31
1.3
1.4
—
—
—
0
0
6
24
2.51
1.30
1.3
1.2
113.33
114.84
%
—
6
19
24
154
1.57
1.26
2.2
3.4
1.21
1.54
%
0.25
19
136
18
108
1.68
1.22
1.3
1.5
—
—
—
0
0
28
188
1.50
1.22
2.4
1.6
4.04
4.14
iu/l
0.03
12
60
496
4642
1.13
1.20
19.2
17.0
1.31
1.30
inr
0.05
106
1303
215
2414
0.86
1.16
4.9
4.3
0.00
0.00
estimate
0.69
70
803
161
1394
1.18
1.16
1.3
1.3
5.69
15.24
u/ml
2.15
47
494
105
878
1.22
1.10
10.7
7.2
11.08
10.14
mmol/l
0.66
98
838
21
136
1.56
1.09
1.2
1.2
—
—
—
0
0
66
823
0.79
1.09
4.2
3.8
1.23
1.23
mmol/l
0.20
59
717
317
2904
1.13
1.06
2.8
2.5
57.22
88.91
u/l
0.59
296
2659
10
52
1.93
1.06
3.5
1.7
—
—
—
0
0
8
147
0.54
1.04
1.6
1.4
—
—
—
0
0
87
1045
0.82
1.03
4.0
3.4
—
—
—
0
0
21
139
1.52
1.00
2.3
3.1
—
2271.69
—
0
13
7
35
2.01
1.00
1.1
1.6
—
—
—
0
0
7
37
1.90
0.94
1.0
1.0
—
—
—
0
0
11
63
1.75
0.90
1.1
1.1
—
—
—
0
0
106
1230
0.85
0.89
5.5
4.7
35.52
32.94
%
1.52
67
799
33
246
1.35
0.88
1.5
1.2
—
—
—
0
0
36
275
1.32
0.83
1.5
1.7
—
—
—
0
0
55
446
1.25
0.81
1.3
1.2
115.92
219.91
u/ml
1.02
50
396
19
130
1.47
0.81
1.3
1.2
313.80
283.36
u/ml
—
10
75
453
4288
1.10
0.81
2.4
2.6
—
—
—
0
0
23
164
1.41
0.80
1.6
1.7
41.91
42.02
nmol/l
0.01
23
155
6
34
1.77
0.76
1.2
1.1
135.17
194.58
iu/ml
—
6
34
13
83
1.57
0.75
1.2
1.9
4.75
4.56
mg/l
0.05
13
78
5
24
2.09
0.74
1.0
1.1
—
—
—
0
0
21
151
1.40
0.71
1.1
1.2
8.52
42.46
u/ml
—
5
11
7
40
1.75
0.71
1.3
1.2
196.03
162.59
pmol/l
—
7
40
5
26
1.93
0.70
1.0
1.1
—
—
—
0
0
36
283
1.28
0.70
1.3
1.5
268.90
281.40
ug/g
0.15
21
167
7
42
1.67
0.68
1.1
1.1
—
—
—
0
0
50
412
1.22
0.67
3.1
3.5
643.03
1028.03
u/ml
0.26
40
365
45
368
1.23
0.65
1.9
2.2
178.75
1058.38
ug/l
0.95
40
346
52
621
0.83
0.64
4.2
3.7
1.71
2.01
mmol/l
0.20
37
470
37
298
1.25
0.61
1.4
1.2
—
—
—
0
0
0
21
0.00
0.60
0.0
1.3
—
—
—
0
0
15
209
0.71
0.60
1.3
1.4
—
—
—
0
0
6
35
1.72
0.57
1.2
1.1
—
—
—
0
0
55
467
1.19
0.57
1.2
1.2
131.15
125.92
iu/ml
0.03
15
179
28
222
1.27
0.54
2.0
2.3
134.33
126.85
g/l
0.68
12
166
17
125
1.37
0.54
1.5
1.6
63.42
67.53
%
0.16
12
78
67
583
1.16
0.53
1.6
1.5
—
—
—
0
0
15
202
0.74
0.50
1.2
1.7
—
—
—
0
0
87
776
1.13
0.49
2.5
2.1
380.23
369.64
nmol/l
0.16
78
698
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
7
45
1.56
0.49
1.7
1.6
—
—
—
0
0
7
46
1.53
0.48
1.7
1.6
—
—
—
0
0
16
119
1.35
0.48
4.4
3.5
—
—
—
0
0
101
912
1.12
0.47
2.5
3.0
209.43
216.72
ng/l
0.06
89
845
15
199
0.75
0.47
1.2
1.4
33.78
767.84
e6/l
—
9
164
15
199
0.75
0.47
1.2
1.3
10.00
57.40
e6/l
—
9
156
317
3320
0.94
0.45
4.8
4.3
—
—
—
0
0
17
130
1.31
0.44
1.2
1.6
—
—
—
0
0
10
140
0.71
0.43
1.2
1.6
—
—
—
0
0
16
122
1.32
0.42
1.4
1.9
191.94
219.29
pmol/l
0.45
16
112
5
32
1.57
0.42
1.0
1.1
—
—
—
0
0
8
58
1.38
0.41
1.6
1.5
—
—
—
0
0
8
58
1.38
0.41
1.6
1.5
—
—
—
0
0
0
16
0.00
0.41
0.0
2.1
—
8.44
—
0
9
0
17
0.00
0.40
0.0
1.1
—
21.55
—
0
11
5
34
1.47
0.40
1.0
1.7
1.54
2.58
nmol/l
—
5
28
5
34
1.47
0.40
1.0
1.4
29.80
21.43
%
—
5
21
5
36
1.39
0.38
1.0
1.2
—
—
—
0
0
5
36
1.39
0.38
1.2
1.1
—
—
—
0
0
97
893
1.10
0.34
2.5
2.6
6.19
6.58
ug/l
0.11
84
778
12
156
0.77
0.34
1.3
1.1
—
—
—
0
0
41
358
1.15
0.34
3.7
3.8
67.22
221.97
mg/l
0.49
31
297
26
218
1.20
0.34
1.4
1.2
7.78
10.11
u/ml
—
6
40
6
44
1.37
0.34
1.3
1.4
—
—
—
0
0
11
82
1.35
0.34
1.2
1.8
—
—
—
0
0
41
359
1.15
0.33
3.7
3.8
47.38
94.53
mg/l
0.66
33
298
130
1216
1.08
0.33
8.8
7.4
—
—
—
0
0
31
267
1.17
0.31
1.5
1.9
—
—
—
0
0
121
1132
1.08
0.31
3.5
4.3
3.50
16.52
ug/l
2.30
98
943
11
84
1.31
0.30
1.0
1.1
1.33
0.94
u/ml
—
6
45
8
111
0.72
0.28
1.1
1.6
—
—
—
0
0
8
111
0.72
0.28
1.1
1.6
—
—
—
0
0
9
117
0.77
0.27
1.4
1.4
—
—
—
0
0
9
119
0.75
0.27
1.4
1.4
—
—
—
0
0
9
119
0.75
0.27
1.4
1.4
—
—
—
0
0
9
119
0.75
0.27
1.4
1.4
—
—
—
0
0
9
119
0.75
0.27
1.4
1.4
—
—
—
0
0
9
120
0.75
0.27
1.4
1.4
—
—
—
0
0
18
215
0.83
0.27
2.2
2.6
16.27
15.63
%
—
9
110
82
761
1.08
0.26
1.8
1.7
1.51
1.54
%
0.17
71
633
32
361
0.88
0.25
2.8
2.8
—
—
—
0
0
14
168
0.83
0.23
2.7
3.0
4.56
4.28
e9/l
0.34
14
168
5
40
1.25
0.22
1.0
1.3
—
—
—
0
0
10
79
1.27
0.22
1.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.4
—
8.37
—
0
12
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.0
—
—
—
0
0
382
3741
1.03
0.19
4.0
3.9
31.63
50.32
ng/l
1.15
290
2810
15
175
0.86
0.19
2.7
3.1
59.80
59.20
%
0.13
15
175
23
259
0.89
0.18
1.2
1.6
—
—
—
0
0
7
58
1.21
0.18
2.1
1.5
0.83
1.00
g/l
—
7
58
7
59
1.19
0.18
1.1
1.2
—
—
—
0
0
7
59
1.19
0.18
1.1
1.2
—
—
—
0
0
10
121
0.82
0.18
2.4
7.0
7.66
7.47
mmol/l
—
5
105
19
214
0.89
0.16
1.1
1.3
—
—
—
0
0
38
351
1.09
0.15
1.3
1.7
—
—
—
0
0
9
79
1.14
0.15
1.0
1.2
—
—
—
0
0
11
93
1.18
0.14
1.5
1.5
—
—
—
0
0
11
93
1.18
0.14
1.5
1.5
—
—
—
0
0
11
93
1.18
0.14
1.5
1.5
—
—
—
0
0
19
170
1.12
0.13
1.3
1.7
—
—
—
0
0
21
231
0.91
0.12
1.3
1.7
—
—
—
0
0
47
444
1.06
0.12
10.3
3.8
50.95
48.68
%
0.25
47
438
18
162
1.11
0.12
1.2
1.6
—
—
—
0
0
5
44
1.14
0.10
1.0
1.0
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
5
45
1.11
0.10
1.0
1.1
—
—
—
0
0
5
48
1.04
0.09
1.0
1.1
306.60
227.17
mg/l
—
5
41
12
107
1.12
0.08
1.4
1.6
—
—
—
0
0
5
61
0.82
0.08
1.2
1.4
—
—
—
0
0
5
61
0.82
0.08
1.2
1.4
—
—
—
0
0
5
64
0.78
0.08
1.2
1.6
—
—
—
0
0
10
88
1.14
0.08
1.1
1.3
—
—
—
0
0
6
71
0.84
0.07
1.0
1.0
—
—
—
0
0
8
74
1.08
0.07
1.1
1.0
—
—
—
0
0
25
235
1.07
0.07
1.3
1.4
—
—
—
0
0
46
443
1.04
0.06
1.7
2.0
2.89
1.58
ug/l
0.25
41
387
23
243
0.95
0.05
1.3
1.6
—
—
—
0
0
12
131
0.92
0.05
1.2
2.0
—
—
—
0
0
196
1939
1.01
0.04
4.8
4.4
1.02
1.02
kg/l
0.30
25
300
24
229
1.05
0.04
7.4
3.3
1.39
1.56
mmol/l
0.72
24
224
11
101
1.09
0.04
1.5
1.6
—
—
—
0
0
42
409
1.03
0.03
2.0
1.9
—
—
—
0
0
16
168
0.95
0.02
1.4
1.6
—
—
—
0
0
16
168
0.95
0.02
1.4
1.6
—
—
—
0
0
33
322
1.03
0.02
1.1
1.6
—
—
—
0
0
38
373
1.02
0.01
1.8
1.8
—
—
—
0
0
10
94
1.06
0.01
1.1
1.1
—
—
—
0
0
10
98
1.02
0.00
1.0
1.0
—
—
—
0
0
11
108
1.02
0.00
1.1
1.7
—
—
—
0
0
13
129
1.01
0.00
1.3
1.6
—
—
—
0
0
11
107
1.03
0.00
1.1
2.0
—
—
—
0
0
15
147
1.02
0.00
1.3
1.5
—
—
—
0
0
105
1055
0.99
0.00
1.3
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
49
1.02
-0.00
1.2
1.3
—
—
—
0
0
5
50
1.00
-0.00
1.0
1.1
47.60
36.70
mg/l
—
5
42
5
49
1.02
-0.00
1.2
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.5
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
7
79
0.89
-0.00
1.1
1.7
—
—
—
0
0
9
98
0.92
-0.00
1.2
1.0
—
2.05
—
0
34
0
5
0.00
-0.00
0.0
2.0
—
—
—
0
0
94
940
1.00
-0.00
2.2
2.2
0.21
0.21
g/l
0.16
86
873
6
67
0.89
-0.00
1.8
2.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
10.67
—
0
6
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.8
—
85.54
—
0
18
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
63
0.95
-0.00
1.0
1.2
—
—
—
0
0
5
58
0.86
-0.00
1.2
1.5
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint MACULAR_CYST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MACULAR_CYST | 0.698 [0.53, 0.92] | 0.01 |
| Birth year | 1.001 [0.99, 1.01] | 0.778 |
During the follow-up period (1.1.1998 — 31.12.2019), 119 out of 1473 females with MACULAR_CYST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| MACULAR_CYST | 0.688 [0.5, 0.94] | 0.018 |
| Birth year | 0.988 [0.98, 1.0] | 0.014 |
During the follow-up period (1.1.1998 — 31.12.2019), 104 out of 1084 males with MACULAR_CYST died.
Mortality risk
Mortality risk for people of age
years, who have MACULAR_CYST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.079% | 0.103% |
| 5 | 0.537% | 0.804% |
| 10 | 1.258% | 1.964% |
| 15 | 2.398% | 4.017% |
| 20 | 4.339% | 6.824% |
Relationships between endpoints
↥Index endpoint: MACULAR_CYST – Macular cyst
GWS hits: 3
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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