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Other osteochondropathies

DOID EFO Endpoint Browser PheWeb

M13_OSTEOCHONDROPATHY

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M93
  • Hospital discharge: ICD-9 — 7322|732[7-9]
  • Hospital discharge: ICD-8 — 722
  • Hospital discharge: excluded ICD-8 — 72209|7222[8-9]
  • Cause of death: ICD-10 — M93
  • Cause of death: ICD-9 — 7322|732[7-9]
  • Cause of death: ICD-8 — 722
  • Cause of death: excluded ICD-8 — 72209|7222[8-9]

2 out of 7 registries used, show all original rules.

2939

4. Check minimum number of events

None

2939

5. Include endpoints

None

2939

6. Filter based on genotype QC (FinnGen only)

2939

Control definitions (FinnGen only)

Control exclude
M13_OTHERBONE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M91-M94
Name in latin
Aliae osteochondropathiae

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26291 10313 15871
Only index persons 24429 9765 14664
Unadjusted period prevalence (%)
Whole population 0.38 0.30 0.44
Only index persons 0.48 0.36 0.56
Median age at first event (years)
Whole population 22.35 23.72 21.33
Only index persons 21.66 22.98 20.78

-FinnGen-

Key figures

All Female Male
Number of individuals 2939 1441 1498
Unadjusted period prevalence (%) 0.58 0.49 0.66
Median age at first event (years) 26.22 24.99 27.41

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2636
Matched controls
26360
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M93.2
ICD-10 Finland
Osteochondritis dissecans
11113.9
323.0
797
*
72221
ICD-8 Finland
Osteochondrosis, Dissecans
+∞
323.0
433
*
7327A
ICD-9 Finland
Osteochondropathies, Osteochondritis dissecans[OSTEOCHONDRITIS DISSECANS GENUS]
+∞
323.0
309
*
M93.1
ICD-10 Finland
Kienböck disease of adults
1586.0
152.6
147
*
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
6.2
144.5
427
801
M93.9
ICD-10 Finland
Osteochondropathy, unspecified
366.0
140.2
140
*
72299
ICD-8 Finland
Unspecified forms of osteochondrosis
+∞
131.3
125
*
1220
FHL
Arthroscopy
7.6
123.1
305
443
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
32.9
121.4
161
52
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.4
117.3
690
2499
72222
ICD-8 Finland
Osteochondrosis, Tuberositatis tibiae (Schlatter)
+∞
101.7
97
*
M93.8
ICD-10 Finland
Other specified osteochondropathies
+∞
99.6
95
*
NGF40
NOMESCO Finland
Repair of defect of cartilage in the knee joint with transplant
76.6
90.9
103
14
7327X
ICD-9 Finland
Osteochondropathies, Osteochondritis dissecans[OSTEOCHONDRITIS DISSECANS ALIA LOCO DEFINITO]
+∞
90.1
86
*
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
5.1
89.9
305
656
72288
ICD-8 Finland
Other specified forms of osteochondrosis
+∞
89.0
85
*
NGF30
NOMESCO Finland
Fixation of loose body of joint of knee
134.5
85.5
91
7
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
19.0
84.9
132
73
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
6.7
83.4
225
364
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.5
79.5
415
1329
7328A
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[JALKATERÄN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
76.4
73
*
9102
FHL
Trepanation or removal of the local bone process
28.9
75.5
103
37
7328B
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[MUIDEN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
75.4
72
*
1225
FHL
Arthroscopy and other therapeutic procedure
12.7
68.0
124
102
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.4
64.2
251
619
72211
ICD-8 Finland
Osteochondrosis, Coxae planae
+∞
63.8
61
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.6
63.3
317
973
M93.0
ICD-10 Finland
Slipped upper femoral epiphysis (nontraumatic)
+∞
61.7
59
*
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.0
59.6
380
1390
M25.5
ICD-10 Finland
Pain in joint
2.1
58.0
839
4748
72219
ICD-8 Finland
Osteochondrosis, Coxae juvenilis NUD
+∞
50.1
48
*
72210
ICD-8 Finland
Osteochondrosis, Epiphyseolysis capitis femoris
+∞
49.1
47
*
N02AX02
ATC
tramadol; systemic, rectal
1.9
49.0
1099
7253
M01AX05
ATC
glucosamine; oral
2.4
46.5
458
2136
1224
FHL
Arthroscopy and loose removal
27.9
43.9
60
22
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.6
43.1
361
1542
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
42.9
1220
8590
WX320
NOMESCO Finland
Spinalanesthesy
2.1
42.7
590
3201
ZXA05
NOMESCO Finland
Left side
2.0
42.0
638
3594
72220
ICD-8 Finland
Osteochondrosis, Malacia ossia lunati (Kienböck)
+∞
40.7
39
*
1223
FHL
Arthroscopy and articular cartilage surgery
9.4
40.0
84
92
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.8
39.5
282
1092
ZXA00
NOMESCO Finland
Right side
1.9
38.0
650
3811
B01AB05
ATC
enoxaparin; parenteral
1.9
37.7
722
4409
N02BE01
ATC
paracetamol; systemic, rectal
1.9
36.0
2153
18558
L15
ICPC
Knee symptom/complaint
2.0
35.3
524
2899
NHF30
NOMESCO Finland
Fixation of loose fragment from ankle joint
182.3
34.8
36
*
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
5.2
34.3
109
215
M23.4
ICD-10 Finland
Loose body in knee
11.7
34.3
64
56
NHA30
NOMESCO Finland
Exploration of joint of ankle or foot, arthroscopic
13.0
33.9
60
47
72223
ICD-8 Finland
Osteochondrosis, Ossium metarsalium et ossis navicularis pedis (Köhler)
+∞
33.4
32
*
M01AH05
ATC
etoricoxib; oral
1.6
33.3
1522
11941
9103
FHL
Partial or complete bone removal
28.6
33.3
45
16
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
6.5
33.2
88
139
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.6
33.0
255
1033
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.5
31.2
154
462
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.7
29.9
105
232
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.2
29.4
337
1664
M79.6
ICD-10 Finland
Pain in limb
1.7
28.8
845
5799
M09AX01
ATC
hyaluronic acid; parenteral
3.4
28.2
141
428
7322A
ICD-9 Finland
Osteochondropathies, Nontraumatic slipped upper femoral epiphysis
+∞
28.2
27
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
5.5
27.7
84
158
N02AJ06
ATC
codeine and paracetamol; systemic
1.6
26.9
961
6920
M16.7
ICD-10 Finland
Other secondary coxarthrosis
11.0
26.8
51
47
72901
ICD-8 Finland
Other diseases of joint, Corpus liberum articuli
25.0
26.6
37
15
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
4.6
26.0
93
210
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
2.4
25.9
237
1049
N03AX16
ATC
pregabalin; oral
1.8
25.6
564
3533
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
4.4
25.6
94
218
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.3
25.4
244
1107
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
6.0
24.9
70
120
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
24.9
884
6325
M01AC06
ATC
meloxicam; systemic, rectal
1.6
24.8
846
5993
M22.4
ICD-10 Finland
Chondromalacia patellae
3.5
24.5
119
353
7328X
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[OSTEOCHONDROPATHIAE ALIA DEFINITA]
+∞
24.0
23
*
NDG20
NOMESCO Finland
Fusion of wrist, partial
10.6
23.3
45
43
72298
ICD-8 Finland
NA
+∞
22.9
22
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
22.9
841
6037
SPAT1153
SPAT
Removal of sutures
1.6
22.9
694
4746
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.3
22.8
234
1092
N03AX12
ATC
gabapentin; oral
1.9
22.2
376
2153
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
3.9
21.8
91
239
71301
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) genus
12.0
21.5
39
33
M17.5
ICD-10 Finland
Other secondary gonarthrosis
5.8
21.4
61
107
M01AE02
ATC
naproxen; oral, rectal
1.5
20.9
1407
11492
NF1AA
NOMESCO Finland
Hip X-ray examination
2.4
20.9
186
812
M91.1
ICD-10 Finland
Juvenile osteochondrosis of head of femur [Legg-Calvé-Perthes]
+∞
20.9
20
*
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
7.0
20.7
51
74
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.4
20.5
175
748
M01AB05
ATC
diclofenac; systemic, rectal
1.5
20.4
1630
13770
M01AE01
ATC
ibuprofen; systemic, rectal
1.7
20.3
2323
21347
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
20.2
465
2932
M19.2
ICD-10 Finland
Other secondary arthrosis
5.5
20.1
60
112
S18
ICPC
Laceration/cut
1.5
20.1
901
6733
NHF20
NOMESCO Finland
Operation for debridement of ankle joint, open
18.9
19.9
30
16
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.6
19.8
152
613
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
9.0
19.6
41
46
X58
ICD-10 Finland
Exposure to other specified factors
1.8
19.5
367
2173
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.6
19.4
625
4308
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
19.3
344
1998
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
19.3
536
3558
M01AX17
ATC
nimesulide; oral
1.6
18.2
518
3451
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.9
18.2
308
1756
M23.8
ICD-10 Finland
Other internal derangements of knee
2.9
18.2
110
384
M94.2
ICD-10 Finland
Chondromalacia
33.1
18.0
23
7
1221
FHL
Arthroscopy and meniscus surgery
3.4
17.9
88
266
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
4.3
17.7
66
157
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
17.6
588
4080
L90
ICPC
Osteoarthrosis of knee
2.5
17.4
140
578
7152F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,POLVI]
24.2
17.3
24
10
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.3
17.3
170
779
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
2.9
17.2
107
381
M02AA07
ATC
piroxicam; topical
1.5
17.2
777
5771
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.1
16.7
201
1005
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.4
16.4
140
597
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
4.9
16.3
53
110
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
2.3
16.2
147
647
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
16.1
853
6524
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
16.1
217
1138
7329X
ICD-9 Finland
Osteochondropathies, Unspecified osteochondropathy
+∞
15.6
15
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
15.4
962
7576
TQW40
NOMESCO Finland
Remowal of suture of skin
2.1
15.4
172
837
WZA90
NOMESCO Finland
Other doctors statement
1.5
15.4
550
3863
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
7.7
15.3
35
46
72908
ICD-8 Finland
Other diseases of joint, Alii definiti
9.8
15.2
30
31
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
3.6
15.1
68
193
9165
FHL
Removal of osteosynthesis material
3.5
14.9
69
200
L16
ICPC
Ankle symptom/complaint
1.9
14.9
235
1307
ACC51
NOMESCO Finland
Release of median nerve
2.1
14.8
174
860
B01AF01
ATC
rivaroxaban; oral
1.9
14.8
227
1248
S83.3
ICD-10 Finland
Tear of articular cartilage of knee, current
4.3
14.6
53
124
M54.5
ICD-10 Finland
Low back pain
1.4
14.6
752
5699
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
3.0
14.5
85
292
1222
FHL
Arthroscopy and synovial surgery
5.5
14.3
42
78
J01DA01
ATC
[U] cefalexin; systemic
1.4
14.1
1483
12726
Z3226
NOMESCO Finland
Physiotherapist
1.6
14.1
419
2809
NG2AA
NOMESCO Finland
Patella X-ray examination
3.3
13.9
71
222
S93.2
ICD-10 Finland
Rupture of ligaments at ankle and foot level
3.6
13.7
61
172
WX111
NOMESCO Finland
Local infiltration anesthesia
3.1
13.6
75
248
ZXD20
NOMESCO Finland
Day surgery
1.7
13.6
300
1855
72200
ICD-8 Finland
Osteochondrosis, Vertebrae planae
+∞
13.5
13
*
N02AA05
ATC
oxycodone; systemic
1.8
13.5
259
1535
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
6.3
13.5
35
56
S83.2
ICD-10 Finland
Tear of meniscus, current
1.9
13.4
187
995
R4110
NOMESCO Finland
Physiotherapy
1.5
12.9
580
4258
M48.0
ICD-10 Finland
Spinal stenosis
1.8
12.8
223
1282
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.3
12.8
63
193
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.3
12.7
119
536
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
3.8
12.6
52
138
M13.9
ICD-10 Finland
Arthritis, unspecified
2.0
12.5
163
843
M24.0
ICD-10 Finland
Loose body in joint
8.0
12.3
27
34
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.2
12.3
128
602
J01DB01
ATC
cefalexin; oral
1.4
12.2
2002
18260
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
12.2
596
4444
9243
FHL
Plastic of the patella and its tendons
5.0
12.1
38
77
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
15.9
12.1
19
12
RF210
NOMESCO Finland
NA
2.8
11.9
76
278
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
11.8
180
987
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.1
11.8
135
665
NG1DA
NOMESCO Finland
X-ray of knees
3.6
11.7
52
148
J01FF01
ATC
clindamycin; systemic
1.4
11.6
605
4556
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
19.0
11.6
17
9
M92.3
ICD-10 Finland
Other juvenile osteochondrosis of upper limb
+∞
11.5
11
*
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
5.7
11.5
32
57
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
2.0
11.5
151
785
WX212
NOMESCO Finland
Femoral plexus blockade
3.9
11.4
46
120
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
3.0
11.4
65
220
L13
ICPC
Hip symptom/complaint
1.6
11.3
274
1735
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
11.3
775
6128
H02AB06
ATC
prednisolone; systemic
1.3
10.9
985
8129
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
10.8
219
1320
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.6
10.8
314
2087
SPAT1229
SPAT
Assessment of need for aid
2.0
10.7
137
704
M89.0
ICD-10 Finland
Algoneurodystrophy
17.9
10.7
16
9
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
10.6
350
2397
ZXE00
NOMESCO Finland
One hour or less
1.3
10.6
864
7012
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
10.6
619
4751
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
10.6
156
846
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
10.6
373
2595
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
4.8
10.5
34
72
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
10.5
544
4086
R51.80
ICD-10 Finland
Headache
1.5
10.4
328
2221
7323B
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of upper extremity[OSTEOCHONDROSIS JUVENILIS OSSIS LUNATUM CARPI]
+∞
10.4
10
*
L28
ICPC
Limited function/disability (L)
1.6
10.3
264
1700
WX002
NOMESCO Finland
Sedation and analgesia
1.5
10.1
390
2759
84400
ICD-8 Finland
Sprains and strains of knee and leg
3.5
10.1
45
129
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
2.7
10.1
67
251
M01AH02
ATC
rofecoxib; oral
1.6
10.0
239
1509
R03AC02
ATC
salbutamol; inhalant
1.3
10.0
1179
10073
L11
ICPC
Wrist symptom/complaint
1.8
10.0
175
1008
B01AX06
ATC
[U] rivaroxaban; oral
3.2
9.8
50
159
7321A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of hip and pelvis[COXA PLANA (LEGG-CALVô-PERTHES)]
26.1
9.8
13
5
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
4.0
9.8
38
97
NGC00
NOMESCO Finland
Exchange of a loose part of prosthesis in knee joint
8.7
9.8
20
23
NH1AI
NOMESCO Finland
Cone beam CT of ankle
9.6
9.7
19
20
9245
FHL
Reconstruction or plastic surgery of ankle ligaments
5.1
9.7
29
57
J01AA02
ATC
doxycycline; systemic
1.3
9.6
1795
16304
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
9.6
191
1144
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.7
9.6
211
1302
M03BX02
ATC
tizanidine; oral
1.3
9.6
1461
12902
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.6
9.6
244
1570
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
2.0
9.6
114
574
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
9.5
232
1473
M01AE11
ATC
tiaprofenic acid; oral, rectal
2.3
9.4
83
363
N06AX21
ATC
duloxetine; oral
1.6
9.4
233
1486
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
3.6
9.4
41
116
NCF25
NOMESCO Finland
Operation for osteochondritis of elbow joint, arthroscopic
5.0
9.4
29
59
M92.2
ICD-10 Finland
Juvenile osteochondrosis of hand
+∞
9.4
9
*
NCK68
NOMESCO Finland
Shortening or lengthening osteotomy of elbow or forearm, other location
12.4
9.3
16
13
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
12.4
9.3
16
13
M67.4
ICD-10 Finland
Ganglion
1.9
9.3
134
725
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
3.3
9.0
44
136
C03CA01
ATC
furosemide; systemic
1.4
9.0
399
2901
NF1DA
NOMESCO Finland
X-ray of hips
2.8
9.0
54
192
9359
FHL
Other measure in this category
15.6
9.0
14
9
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.1
8.7
100
496
M01AC01
ATC
piroxicam; systemic, rectal
1.5
8.6
263
1768
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
4.0
8.5
32
80
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
9.0
8.5
17
19
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
3.9
8.5
33
85
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.5
199
1252
M92.6
ICD-10 Finland
Juvenile osteochondrosis of tarsus
27.6
8.5
11
*
NGT99
NOMESCO Finland
Other operation on knee or lower leg
27.6
8.5
11
*
NH1AD
NOMESCO Finland
Ankle and foot CT
2.9
8.5
50
177
M92.7
ICD-10 Finland
Juvenile osteochondrosis of metatarsus
90.3
8.4
9
*
NG1AA
SPAT
NA
2.0
8.4
101
512
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.8
8.3
130
721
72209
ICD-8 Finland
Osteochondrosis, spinalis juvenilis (Scheuermann) NUD
+∞
8.3
8
*
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.6
8.3
197
1243
NGC60
NOMESCO Finland
Exchange or addition of patellar part
8.5
8.3
17
20
NGC20
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, normal prosthesis
8.5
8.3
17
20
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.4
8.2
525
4077
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.5
8.1
60
243
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
2.8
8.0
48
172
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
8.0
411
3072
L17
ICPC
Foot/toe symptom/complaint
1.4
8.0
485
3732
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.9
1291
11378
E66.01
ICD-10 Finland
Obesity due to excess calories
1.7
7.8
169
1044
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
7.7
214
1406
NH1BI
NOMESCO Finland
Extensive cone beam CT of ankle
45.1
7.7
9
*
NG1AD
NOMESCO Finland
Knee CT examination
3.4
7.7
35
104
WX110
NOMESCO Finland
Local anesthesy
1.3
7.7
1646
14964
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
7.4
7.7
17
23
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
4.1
7.7
28
69
M77.4
ICD-10 Finland
Metatarsalgia
1.9
7.7
107
572
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
7.6
139
815
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.9
7.6
44
153
J01MA02
ATC
ciprofloxacin; systemic
1.3
7.6
777
6446
SPAT1263
SPAT
Sampling
1.3
7.6
898
7589
A02BC02
ATC
pantoprazole; systemic
1.3
7.6
1374
12231
M43.1
ICD-10 Finland
Spondylolisthesis
2.2
7.6
76
357
72498
ICD-8 Finland
Internal derangement of joint, Alio loco definito
25.1
7.6
10
*
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.6
7.6
189
1208
L12
ICPC
Hand/finger symptom/complaint
1.5
7.5
288
2032
B01AX05
ATC
fondaparinux; parenteral
5.1
7.5
22
43
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
6.2
7.5
19
31
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
2.4
7.5
59
246
M01AB55
ATC
diclofenac, combinations; oral
1.8
7.5
118
661
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
7.5
265
1838
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
3.5
7.5
33
96
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.5
7.4
55
221
S80.0
ICD-10 Finland
Contusion of knee
1.7
7.4
135
793
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
1.9
7.4
105
567
E870A
ICD-9 Finland
Accidental cut, puncture, perforation or haemorrhage during medical care
4.6
7.4
24
53
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
7.3
831
6984
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
7.3
175
1107
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
3.9
7.2
28
73
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.9
7.2
108
594
N06AA09
ATC
amitriptyline; systemic
1.6
7.2
181
1158
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
1.8
7.2
117
659
A02BC03
ATC
lansoprazole; oral
1.3
7.2
549
4364
79199
ICD-8 Finland
Headache
3.4
7.2
33
99
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
7.2
428
3277
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
2.3
7.2
63
280
72499
ICD-8 Finland
Internal derangement of joint, Derangement of other joints
20.1
7.1
10
5
A01
ICPC
Pain general/multiple sites
1.7
7.1
135
801
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
7.0
186
1212
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
3.7
6.9
28
76
G56.2
ICD-10 Finland
Lesion of ulnar nerve
2.1
6.9
74
360
E883A
ICD-9 Finland
Fall into hole or other opening in surface
1.8
6.9
107
598
NFK99
NOMESCO Finland
Other operation on bone of femur
13.8
6.9
11
8
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
3.5
6.9
30
87
M54.6
ICD-10 Finland
Pain in thoracic spine
1.7
6.9
137
827
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
3.3
6.8
32
98
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
3.0
6.8
37
126
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
6.8
429
3311
S83.5
ICD-10 Finland
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
1.9
6.8
100
547
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.4
6.8
301
2187
9255
FHL
Joint auger removal
3.7
6.8
27
73
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
3.2
6.7
32
100
M04AA01
ATC
allopurinol; systemic
1.5
6.7
196
1306
T93.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of lower limb
3.7
6.7
27
74
Z00.0
ICD-10 Finland
General medical examination
1.4
6.7
361
2719
NG1CM
NOMESCO Finland
Knee and lower leg MRI extensive examination with 3 Tesla magnet
7.8
6.6
14
18
ND1AI
NOMESCO Finland
Cone beam CT of wrist
4.2
6.6
23
55
WX290
NOMESCO Finland
Other blockade of nerve
1.2
6.6
1074
9389
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.6
6.6
168
1086
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
6.5
125
743
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
2.4
6.5
53
227
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.5
6.5
215
1473
NFB60
NOMESCO Finland
Demanding prosthetic replacement of hip
6.8
6.5
15
22
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.0
6.5
73
362
WX203
NOMESCO Finland
Infraclavicular plexus blockade
2.4
6.5
52
220
A02BC01
ATC
omeprazole; systemic
1.3
6.5
512
4089
M65.3
ICD-10 Finland
Trigger finger
1.9
6.4
84
443
M54.4
ICD-10 Finland
Lumbago with sciatica
1.4
6.4
323
2402
M92.4
ICD-10 Finland
Juvenile osteochondrosis of patella
70.0
6.4
7
*
9531
FHL
Arthrodesis of the hand joint
7.4
6.4
14
19
R06AE07
ATC
cetirizine; oral
1.2
6.4
949
8208
SAA01
NOMESCO Finland
Simple examination of mouth
1.2
6.4
1685
15511
NDF25
NOMESCO Finland
Operation for osteochondritis of joint of wrist, arthroscopic
3.8
6.4
25
67
M24.1
ICD-10 Finland
Other articular cartilage disorders
8.2
6.3
13
16
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
3.5
6.3
27
78
7176A
ICD-9 Finland
Internal derangement of knee, Loose body in knee
9.3
6.3
12
13
ZZR45
NOMESCO Finland
Sceletal flap
+∞
6.2
6
*
M92.9
ICD-10 Finland
Juvenile osteochondrosis, unspecified
+∞
6.2
6
*
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
4.3
6.2
21
49
L89
ICPC
Osteoarthrosis of hip
2.2
6.2
57
261
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
2.3
6.2
54
241
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.9
6.2
23
59
Z50.1
ICD-10 Finland
Other physical therapy
1.8
6.1
106
615
SPAT1216
SPAT
Assessment of functional ability
1.5
6.1
223
1562
72909
ICD-8 Finland
Other diseases of joint, Unspecified
12.5
6.1
10
8
7152E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,LONKKANIVEL]
12.5
6.1
10
8
S63.3
ICD-10 Finland
Traumatic rupture of ligament of wrist and carpus
2.7
6.1
38
143
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.6
6.1
137
855
NH1CM
NOMESCO Finland
Ankle and foot extensive MRI examination with 3 Tesla magnet
8.6
6.0
12
14
M01AH03
ATC
valdecoxib; oral
1.7
6.0
124
756
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
6.0
519
4192
NG1BM
NOMESCO Finland
Knee and lower leg MRI examination with 3 Tesla magnet
10.0
6.0
11
11
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
2.8
6.0
35
124
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.8
6.0
90
497

Mortality – FinRegistry

↥

Association

Association between endpoint M13_OSTEOCHONDROPATHY and mortality.

Females

Parameter HR [95% CI] p-value
M13_OSTEOCHONDROPATHY 1.062 [0.88, 1.28] 0.522
Birth year 0.993 [0.98, 1.0] 0.122

During the follow-up period (1.1.1998 — 31.12.2019), 155 out of 4483 females with M13_OSTEOCHONDROPATHY died.

Males

Parameter HR [95% CI] p-value
M13_OSTEOCHONDROPATHY 0.818 [0.7, 0.96] 0.011
Birth year 0.989 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 211 out of 6001 males with M13_OSTEOCHONDROPATHY died.

Mortality risk

Mortality risk for people of age

years, who have M13_OSTEOCHONDROPATHY.

N-year risk Females Males
1 0.076% 0.175%
5 0.637% 0.997%
10 1.393% 2.652%
15 2.861% 4.997%
20 5.251% 8.44%

Relationships between endpoints

↥

Index endpoint: M13_OSTEOCHONDROPATHY – Other osteochondropathies

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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