Other osteochondropathies

M13_OSTEOCHONDROPATHY

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M93
  • Hospital discharge: ICD-9 7322|732[7-9]
  • Hospital discharge: ICD-8 722
  • Hospital discharge: excluded ICD-8 72209|7222[8-9]
  • Cause of death: ICD-10 M93
  • Cause of death: ICD-9 7322|732[7-9]
  • Cause of death: ICD-8 722
  • Cause of death: excluded ICD-8 72209|7222[8-9]

2 out of 7 registries used, show all original rules.

2971

4. Check minimum number of events

None

2971

5. Include endpoints

None

2971

6. Filter based on genotype QC (FinnGen only)

2885

Control definitions (FinnGen only)

Control exclude
M13_OTHERBONE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M91-M94
Name in latin
Aliae osteochondropathiae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 26291 10313 15871
Only index persons 24429 9765 14664
Unadjusted period prevalence (%)
Whole population 0.38 0.30 0.44
Only index persons 0.48 0.36 0.56
Median age at first event (years)
Whole population 22.35 23.72 21.33
Only index persons 21.66 22.98 20.78

-FinnGen-

Key figures

All Female Male
Number of individuals 2885 1423 1462
Unadjusted period prevalence (%) 0.59 0.50 0.67
Median age at first event (years) 26.43 25.26 27.56

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2971
Matched controls
29710
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
72221
ICD-8 Finland
Osteochondrosis, Dissecans
+∞
307.7
488
*
7327A
ICD-9 Finland
Osteochondropathies, Osteochondritis dissecans[OSTEOCHONDRITIS DISSECANS GENUS]
+∞
307.7
341
*
M93.2
ICD-10 Finland
Osteochondritis dissecans
6240.8
307.7
908
*
9254
FHL
Arthrotomy (includes biopsy, revision, loose removal, fixation, and similar procedures)
34.8
283.3
180
55
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
6.6
272.9
485
848
1220
FHL
Arthroscopy
7.5
220.0
335
494
NGF40
NOMESCO Finland
Repair of defect of cartilage in the knee joint with transplant
96.1
213.1
111
12
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.4
183.2
851
3109
M93.1
ICD-10 Finland
Kienböck disease of adults
911.0
177.0
172
*
9102
FHL
Trepanation or removal of the local bone process
27.7
176.3
120
45
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
5.5
168.7
350
699
M93.9
ICD-10 Finland
Osteochondropathy, unspecified
546.3
158.4
156
*
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
7.0
157.2
251
387
NHF25
NOMESCO Finland
Operation for debridement of ankle joint, arthroscopic
14.9
156.9
141
99
72299
ICD-8 Finland
Unspecified forms of osteochondrosis
+∞
142.9
136
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.4
125.2
513
1698
M93.8
ICD-10 Finland
Other specified osteochondropathies
+∞
122.8
117
*
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
3.7
114.5
407
1224
72222
ICD-8 Finland
Osteochondrosis, Tuberositatis tibiae (Schlatter)
+∞
112.2
107
*
1225
FHL
Arthroscopy and other therapeutic procedure
9.5
109.6
132
145
72288
ICD-8 Finland
Other specified forms of osteochondrosis
+∞
102.7
98
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.2
101.6
295
767
7327X
ICD-9 Finland
Osteochondropathies, Osteochondritis dissecans[OSTEOCHONDRITIS DISSECANS ALIA LOCO DEFINITO]
+∞
98.5
94
*
1224
FHL
Arthroscopy and loose removal
24.8
96.2
68
28
NGF30
NOMESCO Finland
Fixation of loose body of joint of knee
147.8
94.7
100
7
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.9
89.2
481
1847
7328A
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[JALKATERÄN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
83.7
80
*
1223
FHL
Arthroscopy and articular cartilage surgery
9.8
83.1
97
102
7328B
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[MUIDEN YLIMÄÄRÄISTEN LUIDEN AIHEUTTAMAT OIREET]
+∞
82.7
79
*
M01AX05
ATC
glucosamine; oral
2.5
71.5
531
2379
72211
ICD-8 Finland
Osteochondrosis, Coxae planae
+∞
70.1
67
*
M93.0
ICD-10 Finland
Slipped upper femoral epiphysis (nontraumatic)
+∞
70.1
67
*
M23.4
ICD-10 Finland
Loose body in knee
11.5
69.2
72
64
NHA30
NOMESCO Finland
Exploration of joint of ankle or foot, arthroscopic
12.7
68.5
67
54
9103
FHL
Partial or complete bone removal
25.1
66.8
47
19
WX320
NOMESCO Finland
Spinalanesthesy
2.2
65.6
759
4088
M16.7
ICD-10 Finland
Other secondary coxarthrosis
11.4
64.9
68
61
M25.5
ICD-10 Finland
Pain in joint
2.0
64.7
1076
6612
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.6
63.9
422
1781
72901
ICD-8 Finland
Other diseases of joint, Corpus liberum articuli
26.6
60.9
42
16
N02AX02
ATC
tramadol; systemic, rectal
1.9
60.7
1304
8679
72210
ICD-8 Finland
Osteochondrosis, Epiphyseolysis capitis femoris
+∞
59.6
57
*
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
5.0
58.1
127
262
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
6.4
57.8
97
156
72219
ICD-8 Finland
Osteochondrosis, Coxae juvenilis NUD
+∞
56.4
54
*
L15
ICPC
Knee symptom/complaint
2.0
56.0
740
4157
M17.5
ICD-10 Finland
Other secondary gonarthrosis
6.6
55.4
90
140
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.6
55.3
194
571
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.5
53.0
356
1508
ZXA05
NOMESCO Finland
Left side
2.0
53.0
706
3966
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.8
51.6
1369
9579
B01AB05
ATC
enoxaparin; parenteral
1.9
51.3
887
5438
NDG20
NOMESCO Finland
Fusion of wrist, partial
11.5
50.9
53
47
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
11.8
49.9
51
44
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
4.5
48.5
120
274
N02AJ06
ATC
codeine and paracetamol; systemic
1.8
47.1
1325
9351
M09AX01
ATC
hyaluronic acid; parenteral
3.7
46.9
153
429
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.3
45.4
384
1799
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.4
45.4
338
1498
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
4.3
45.3
119
285
ZXA00
NOMESCO Finland
Right side
1.9
45.2
734
4379
71301
ICD-8 Finland
Osteo-arthritis and allied conditions, Arthritis (arthrosis) genus
14.3
45.1
41
29
72220
ICD-8 Finland
Osteochondrosis, Malacia ossia lunati (Kienböck)
+∞
44.9
43
*
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
4.2
44.5
123
306
NHF30
NOMESCO Finland
Fixation of loose fragment from ankle joint
155.7
43.9
46
*
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
5.6
41.2
79
145
M01AH05
ATC
etoricoxib; oral
1.7
41.1
1859
14712
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
2.3
40.6
325
1484
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.4
40.0
312
1408
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.2
39.1
345
1641
M79.6
ICD-10 Finland
Pain in limb
1.7
38.8
1204
8591
M19.2
ICD-10 Finland
Other secondary arthrosis
5.9
38.0
69
120
N03AX16
ATC
[U] pregabalin
1.8
37.9
664
4029
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
3.3
37.7
147
462
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
4.2
36.9
99
241
M22.4
ICD-10 Finland
Chondromalacia patellae
3.3
35.9
136
420
L90
ICPC
Osteoarthrosis of knee
2.8
35.5
188
704
N02BE01
ATC
paracetamol; systemic, rectal
2.0
35.2
2560
22580
72223
ICD-8 Finland
Osteochondrosis, Ossium metarsalium et ossis navicularis pedis (Köhler)
+∞
34.4
33
*
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
2.6
33.3
199
792
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
4.2
33.2
88
212
S93.2
ICD-10 Finland
Rupture of ligaments at ankle and foot level
4.5
33.0
82
188
NF1AA
NOMESCO Finland
Hip X-ray examination
2.4
32.4
230
994
M01AC06
ATC
meloxicam; systemic, rectal
1.6
30.8
980
6933
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
3.4
30.8
113
342
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
30.6
990
7031
N03AX12
ATC
[U] gabapentin; oral
1.9
30.4
470
2725
7322A
ICD-9 Finland
Osteochondropathies, Nontraumatic slipped upper femoral epiphysis
+∞
30.3
29
*
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
29.1
959
6824
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
4.0
28.8
82
209
NDA30
NOMESCO Finland
Exploration of joint of wrist or hand, arthroscopic
5.4
28.7
57
108
X58
ICD-10 Finland
Exposure to other specified factors
1.8
27.2
461
2742
72298, ,
ICD-8 Finland
+∞
27.1
26
*
M16.3
ICD-10 Finland
Other dysplastic coxarthrosis
6.6
26.8
43
66
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.6
26.2
698
4696
X59
ICD-10 Finland
Exposure to unspecified factor
1.7
25.9
566
3616
M24.0
ICD-10 Finland
Loose body in joint
9.5
25.3
30
32
NHF20
NOMESCO Finland
Operation for debridement of ankle joint, open
22.8
25.2
36
16
7328X
ICD-9 Finland
Osteochondropathies, Other specified forms of osteochondropathy[OSTEOCHONDROPATHIAE ALIA DEFINITA]
+∞
25.0
24
*
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.5
25.0
164
683
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.2
24.9
215
1009
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
3.7
24.7
78
214
M23.8
ICD-10 Finland
Other internal derangements of knee
2.7
24.5
135
516
WX111
NOMESCO Finland
Local infiltration anesthesia
3.1
24.4
103
340
M01AB05
ATC
diclofenac; systemic, rectal
1.5
23.9
1871
15783
72908
ICD-8 Finland
Other diseases of joint, Alii definiti
8.1
23.9
32
40
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
4.6
23.8
57
127
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.2
23.2
201
944
1221
FHL
Arthroscopy and meniscus surgery
3.1
23.1
95
309
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.0
22.8
249
1279
M91.1
ICD-10 Finland
Juvenile osteochondrosis of head of femur [Legg-Calvé-Perthes]
231.7
22.6
23
*
S18
ICPC
Laceration/cut
1.5
22.4
1176
9125
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
22.3
388
2318
ND1AA
NOMESCO Finland
Wrist X-ray examination
2.2
22.3
187
867
Z3226
NOMESCO Finland
Physiotherapist
1.7
22.1
482
3066
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
5.4
21.8
43
81
SPAT1153
SPAT
Removal of sutures
1.5
21.7
783
5615
M01AE02
ATC
naproxen; oral, rectal
1.5
21.7
1613
13352
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
21.6
2659
24501
1222
FHL
Arthroscopy and synovial surgery
4.9
21.5
47
97
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
21.2
974
7339
NGK30
NOMESCO Finland
Angulation, rotation or displacement osteotomy of knee or lower leg
5.5
21.2
41
76
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
20.9
381
2304
M01AX17
ATC
nimesulide; oral
1.6
20.8
578
3901
WZA90
NOMESCO Finland
Other medical or dental certificate
1.6
20.7
659
4588
ZXD20
NOMESCO Finland
Day surgery
1.8
20.7
349
2064
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
2.6
20.5
122
485
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
20.5
290
1626
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
3.7
20.4
64
175
NG2AA
NOMESCO Finland
Patella X-ray examination
3.1
20.3
84
274
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.1
20.1
186
896
9165
FHL
Removal of osteosynthesis material
3.3
20.1
74
225
M02AA07
ATC
piroxicam; topical
1.5
20.0
869
6456
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.3
20.0
155
695
TQW40
NOMESCO Finland
Remowal of suture of skin
2.1
19.7
198
986
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.1
19.7
184
891
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
5.3
19.7
39
74
R4110
NOMESCO Finland
Physiotherapy
1.5
19.6
704
5024
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
19.6
1150
9049
S83.3
ICD-10 Finland
Tear of articular cartilage of knee, current
3.8
19.4
59
158
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.1
18.9
177
858
M94.2
ICD-10 Finland
Chondromalacia
23.8
18.6
26
11
J01FF01
ATC
clindamycin; systemic
1.5
18.6
720
5215
L13
ICPC
Hip symptom/complaint
1.7
18.5
411
2619
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
18.4
679
4865
B01AF01
ATC
rivaroxaban; oral
1.8
18.4
285
1641
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
4.1
18.3
50
124
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
18.2
749
5486
NF1DA
NOMESCO Finland
X-ray of hips
3.5
18.0
61
176
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.1
18.0
168
813
M48.0
ICD-10 Finland
Spinal stenosis
1.8
17.8
274
1574
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
4.3
17.8
45
105
J01DA01
ATC
[U] cefalexin
1.4
17.6
1677
14268
ACC51
NOMESCO Finland
Release of median nerve
2.0
17.5
209
1107
NGT60
NOMESCO Finland
Forcible manipulation of knee joint
4.7
17.3
39
83
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.8
17.3
271
1566
M54.5
ICD-10 Finland
Low back pain
1.4
17.2
970
7532
NCF25
NOMESCO Finland
Operation for osteochondritis of elbow joint, arthroscopic
5.6
17.0
32
58
L16
ICPC
Ankle symptom/complaint
1.7
16.7
315
1918
7329X
ICD-9 Finland
Osteochondropathies, Unspecified osteochondropathy
+∞
16.7
16
*
72200
ICD-8 Finland
Osteochondrosis, Vertebrae planae
+∞
16.7
16
*
9245
FHL
Reconstruction or plastic surgery of ankle ligaments
5.5
16.7
32
59
7321A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of hip and pelvis[COXA PLANA (LEGG-CALVô-PERTHES)]
170.9
16.5
17
*
RF210, ,
NOMESCO Finland
2.7
16.2
89
340
S83.2
ICD-10 Finland
Tear of meniscus, current
1.9
15.9
217
1201
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.8
15.7
251
1458
R03AC02
ATC
salbutamol; inhalant
1.4
15.7
1477
12441
J01DB01
ATC
cefalexin; oral
1.5
15.7
2341
21303
M92.3
ICD-10 Finland
Other juvenile osteochondrosis of upper limb
+∞
15.6
15
*
7152F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,POLVI]
11.8
15.5
28
24
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
3.9
15.4
44
113
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.7
15.4
278
1673
WX002
NOMESCO Finland
Sedation and analgesia
1.5
15.2
456
3114
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
4.6
15.2
35
76
B01AX06
ATC
[U] rivaroxaban
3.2
15.1
58
182
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
15.0
943
7422
ZXE00
NOMESCO Finland
One hour or less
1.4
15.0
989
7848
M01AH01
ATC
celecoxib; oral
1.6
15.0
411
2750
TNX50
NOMESCO Finland
Removal of cutom molded cast and internal stretch
2.1
14.9
136
653
NG1DA
NOMESCO Finland
X-ray of knees
3.2
14.8
58
184
J01AA02
ATC
doxycycline; systemic
1.4
14.6
2071
18521
N02AA05
ATC
oxycodone; systemic
1.6
14.6
370
2429
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
2.8
14.3
71
258
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
1.8
14.0
225
1308
T93.3
ICD-10 Finland
Sequelae of dislocation, sprain and strain of lower limb
4.4
13.8
34
78
9243
FHL
Plastic of the patella and its tendons
3.8
13.8
42
113
L11
ICPC
Wrist symptom/complaint
1.7
13.8
240
1429
NDF25
NOMESCO Finland
Operation for osteochondritis of joint of wrist, arthroscopic
4.6
13.8
32
70
NG1AA, ,
SPAT
1.8
13.6
212
1222
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
1.9
13.6
175
951
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
13.5
612
4534
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
13.5
647
4844
M13.9
ICD-10 Finland
Arthritis, unspecified
1.8
13.4
197
1115
NH1AI
NOMESCO Finland
Cone beam CT of ankle
6.1
13.4
23
38
M01AC01
ATC
piroxicam; systemic, rectal
1.6
13.4
299
1903
H02AB06
ATC
prednisolone; systemic
1.3
13.2
1190
9863
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
5.8
13.2
24
42
L89
ICPC
Osteoarthrosis of hip
2.5
13.1
82
335
M01AH02
ATC
rofecoxib; oral
1.7
13.0
270
1684
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
13.0
709
5424
NDG30
NOMESCO Finland
Fusion of wrist, total
6.1
12.9
22
36
L28
ICPC
Limited function/disability (L)
1.6
12.9
355
2373
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
3.2
12.9
49
153
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
12.8
445
3128
Z50.1
ICD-10 Finland
Other physical therapy
2.0
12.7
130
652
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
12.6
379
2582
NDK99
NOMESCO Finland
Other operation on bone of hand or wrist
15.5
12.6
20
13
R51.80
ICD-10 Finland
Headache
1.5
12.6
407
2817
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.7
12.6
263
1644
M92.6
ICD-10 Finland
Juvenile osteochondrosis of tarsus
70.2
12.6
14
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.9
12.6
164
895
WX212
NOMESCO Finland
Femoral plexus blockade
2.9
12.5
58
203
L17
ICPC
Foot/toe symptom/complaint
1.4
12.5
683
5221
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
17.4
12.5
19
11
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
3.8
12.4
37
98
EB1AA
NOMESCO Finland
Intraoral radiographic dental examination
1.3
12.2
1507
13017
84400
ICD-8 Finland
Sprains and strains of knee and leg
3.1
12.2
49
158
S80.0
ICD-10 Finland
Contusion of knee
1.8
12.1
198
1157
NGC20
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, normal prosthesis
6.0
12.1
21
35
NGC00
NOMESCO Finland
Exchange of a loose part of prosthesis in knee joint
8.7
12.0
25
29
M03BX02
ATC
tizanidine; oral
1.3
11.9
1703
14992
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.1
11.9
117
578
A02BC02
ATC
pantoprazole; systemic
1.3
11.8
1736
15335
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
2.4
11.7
78
329
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.4
11.6
487
3550
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
2.7
11.5
61
230
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
3.4
11.5
40
118
NDK10
NOMESCO Finland
Incision or excision of a bone of hand
10.1
11.5
22
22
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
9.3
11.5
23
25
SPAT1229
SPAT
Assessment of need for aid
1.9
11.5
152
834
M87.0
ICD-10 Finland
Idiopathic aseptic necrosis of bone
4.4
11.4
28
64
N06AX21
ATC
duloxetine; oral
1.6
11.4
298
1968
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
11.2
212
1290
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
11.2
452
3265
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.5
11.2
371
2578
NH1AD
NOMESCO Finland
Ankle and foot CT
2.5
11.2
66
263
WX110
NOMESCO Finland
Infiltration anesthesia
1.3
11.1
1978
17863
M77.4
ICD-10 Finland
Metatarsalgia
1.8
11.0
155
867
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
2.7
11.0
56
207
M43.1
ICD-10 Finland
Spondylolisthesis
2.2
11.0
95
448
M89.0
ICD-10 Finland
Algoneurodystrophy
13.9
11.0
18
13
Z01.6
ICD-10 Finland
Radiological examination, not elsewhere classified
1.6
10.9
258
1664
J01MA02
ATC
ciprofloxacin; systemic
1.3
10.9
921
7514
TPH04
NOMESCO Finland
Cathetrisation of vein
1.4
10.8
510
3791
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
2.3
10.6
78
344
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
5.3
10.6
21
40
NCK68
NOMESCO Finland
Shortening or lengthening osteotomy of elbow or forearm, other location
11.2
10.5
19
17
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
3.3
10.5
39
120
B01AX05
ATC
fondaparinux; parenteral
4.6
10.5
24
52
7323B
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of upper extremity[OSTEOCHONDROSIS JUVENILIS OSSIS LUNATUM CARPI]
+∞
10.4
10
*
L12
ICPC
Hand/finger symptom/complaint
1.5
10.3
407
2925
ND1AI
NOMESCO Finland
Cone beam CT of wrist
3.8
10.3
31
83
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
3.1
10.3
41
132
WX203
NOMESCO Finland
Infraclavicular plexus blockade
2.5
10.3
64
262
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
2.3
10.3
75
330
9359
FHL
Other measure in this category
23.4
10.2
14
6
Z01.8
ICD-10 Finland
Other specified special examinations
1.4
10.1
552
4202
M01AE11
ATC
tiaprofenic acid; oral, rectal
2.2
10.1
87
410
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.5
10.1
305
2079
L04AX03
ATC
methotrexate; systemic
1.6
10.0
240
1552
NHG20
NOMESCO Finland
Fusion of talocrural joint
4.6
10.0
23
50
B01AB04
ATC
dalteparin; parenteral
1.9
9.9
117
618
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
9.9
69
297
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
1.7
9.9
169
1001
NFK99
NOMESCO Finland
Other operation on bone of femur
26.1
9.8
13
5
M65.3
ICD-10 Finland
Trigger finger
1.9
9.8
116
614
M67.4
ICD-10 Finland
Ganglion
1.7
9.8
169
1005
E66.8
ICD-10 Finland
Other obesity
1.8
9.8
151
870
H02BX01
ATC
methylprednisolone, combinations; systemic
2.0
9.7
100
504
SPAT1263
SPAT
Sampling
1.3
9.7
1018
8525
ZXE20
NOMESCO Finland
More than three and less than five hours
1.5
9.6
305
2101
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
1.8
9.4
130
723
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
3.7
9.4
29
79
L03
ICPC
Low back symptom/complaint
1.3
9.4
668
5293
M92.2
ICD-10 Finland
Juvenile osteochondrosis of hand
+∞
9.4
9
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
9.4
210
1337
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
2.7
9.3
48
179
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
2.4
9.3
62
262
WX702
NOMESCO Finland
Supraglottic ventilation device
1.8
9.3
140
800
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
1.8
9.3
128
713
M01AH03
ATC
valdecoxib; oral
1.8
9.1
142
821
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.5
9.1
299
2074
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.7
9.0
170
1035
M18.9
ICD-10 Finland
Arthrosis of first carpometacarpal joint, unspecified
3.2
9.0
34
106
N06AA09
ATC
amitriptyline; systemic
1.6
9.0
198
1254
N02BF01
ATC
gabapentin; oral
1.6
9.0
196
1239
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.3
8.9
636
5037
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
3.3
8.9
32
97
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
4.9
8.8
19
39
9255
FHL
Joint auger removal
3.6
8.8
28
78
A02BC01
ATC
omeprazole; systemic
1.3
8.8
594
4665
79199
ICD-8 Finland
Headache
3.1
8.8
36
118
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.5
8.8
253
1705
C03CA01
ATC
furosemide; systemic
1.4
8.8
508
3896
NG1AD
NOMESCO Finland
Knee CT examination
2.8
8.7
43
157
ND1BA
NOMESCO Finland
Wrist extensive X-ray examination
2.5
8.6
54
222
Z01.2
ICD-10 Finland
Dental examination
1.3
8.6
1188
10248
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
2.0
8.6
88
444
B01AB10
ATC
tinzaparin; parenteral
1.6
8.6
215
1406
ZXA10
NOMESCO Finland
Bilateral
1.4
8.5
382
2808
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
3.1
8.5
34
110
NDK00
NOMESCO Finland
Excision or incsion of a bone of wrist
10.0
8.5
16
16
M92.7
ICD-10 Finland
Juvenile osteochondrosis of metatarsus
90.3
8.4
9
*
M92.4
ICD-10 Finland
Juvenile osteochondrosis of patella
90.3
8.4
9
*
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
8.4
1992
18285
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
4.5
8.4
20
45
72209
ICD-8 Finland
Osteochondrosis, spinalis juvenilis (Scheuermann) NUD
+∞
8.3
8
*
M91.2
ICD-10 Finland
Coxa plana
+∞
8.3
8
*
2402
FHL
External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)
3.0
8.3
35
117
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
8.3
705
5716
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
2.5
8.2
51
209
7152E
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, secondary[OSTEORTHROSIS SECUNDARIA,LONKKANIVEL]
14.5
8.2
13
9
R60.0
ICD-10 Finland
Localized oedema
1.5
8.2
244
1658
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
6.5
8.2
20
31
WX006
NOMESCO Finland
Intravenous sedation or analgesia without general anesthesia
1.8
8.2
120
682
M01AB16
ATC
aceclofenac; oral
2.1
8.1
69
325
NFK20
NOMESCO Finland
Epiphysiodesis of femur
33.4
8.1
10
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.7
8.1
134
789
NCF20
NOMESCO Finland
Operation for osteochondritis of elbow joint, open
11.7
8.1
14
12
8450B
ICD-9 Finland
Sprains and strains of ankle and foot, Ankle[DISTORSIO,DISTENSIO/RUPT. LIGAMENTI LATERALIS TARSI]
2.7
8.1
42
158
M24.1
ICD-10 Finland
Other articular cartilage disorders
8.9
8.0
16
18
A02BC05
ATC
esomeprazole; systemic
1.3
8.0
957
8096
SPAT1202
SPAT
Intra-articular injection
2.3
8.0
61
274
9057A
ICD-9 Finland
Late effects of musculoskeletal and connective tissue injuries, Late effect of sprain and strain without mention of tendon injury
3.6
8.0
25
69
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.7
8.0
151
921
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
1.9
8.0
96
512
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
8.0
593
4718
7174A
ICD-9 Finland
Internal derangement of knee, Derangement of lateral meniscus
3.9
8.0
23
60
WZC00
NOMESCO Finland
Treatment plan or consultation
1.3
8.0
891
7479
WZA00
NOMESCO Finland
Concise certificate
1.6
8.0
167
1047
WX290
NOMESCO Finland
Other blockage of nerve
1.2
7.9
1316
11561
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
7.9
182
1166
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
1.9
7.9
98
528
R52.9
ICD-10 Finland
Pain, unspecified
1.5
7.9
222
1489
R06AE07
ATC
cetirizine; oral
1.3
7.9
1112
9587
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
2.5
7.9
46
183
ZZH22
NOMESCO Finland
Graft of patients own bone, block
4.4
7.9
19
43
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
2.9
7.9
35
121
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
2.5
7.8
47
190
S63.3
ICD-10 Finland
Traumatic rupture of ligament of wrist and carpus
2.5
7.8
47
190
A02BC03
ATC
lansoprazole; oral
1.3
7.8
628
5049
SAA02
NOMESCO Finland
Basic examination of mouth
1.3
7.8
1839
16786
M25.0
ICD-10 Finland
Haemarthrosis
3.3
7.8
28
85
J01CA04
ATC
amoxicillin; systemic
1.3
7.7
2267
21218
WZB00
NOMESCO Finland
Telephone prescription or other care instructions
1.3
7.7
749
6171
NH1BI
NOMESCO Finland
Extensive cone beam CT of ankle
45.1
7.7
9
*
NGC60
NOMESCO Finland
Exchange or addition of patellar part
6.4
7.7
19
30
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
2.7
7.7
39
145
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
4.5
7.6
18
40
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
2.6
7.6
41
157
M17.2
ICD-10 Finland
Post-traumatic gonarthrosis, bilateral
4.0
7.6
21
53
E66.01
ICD-10 Finland
Obesity due to excess calories
1.5
7.6
230
1568
M15
ICD-10 Finland
Polyarthrosis
1.9
7.6
94
507
L08
ICPC
Shoulder symptom/complaint
1.3
7.6
495
3863
NH1FA
NOMESCO Finland
Weight-bearing X-ray of ankle
3.1
7.6
31
102
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.3
7.6
1027
8806
9269
FHL
Other measure in this category
11.9
7.6
13
11
L01BA01
ATC
methotrexate; systemic
2.0
7.5
82
423
NHE15
NOMESCO Finland
Suture or reinsertion of ligament of ankle
3.2
7.5
28
87
E870A
ICD-9 Finland
Accidental cut, puncture, perforation or haemorrhage during medical care
3.2
7.5
28
87
S83.5
ICD-10 Finland
Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
1.8
7.5
114
655
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
2.1
7.5
69
335
M65.4
ICD-10 Finland
Radial styloid tenosynovitis [de Quervain]
2.0
7.5
75
376
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
2.2
7.5
62
289
J01FA10
ATC
azithromycin; systemic
1.2
7.5
1557
13988
M01AB55
ATC
diclofenac, combinations; oral
1.7
7.4
130
777
RD211, ,
NOMESCO Finland
1.8
7.4
100
554
M19.8
ICD-10 Finland
Other specified arthrosis
1.9
7.4
88
468
UJF92
NOMESCO Finland
Capsular endoscopy
2.3
7.4
54
239
NGT99
NOMESCO Finland
Other operation on knee or lower leg
13.4
7.4
12
9
M24.8
ICD-10 Finland
Other specific joint derangements, not elsewhere classified
3.3
7.4
27
83
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.3
430
3301
NGE15
NOMESCO Finland
Incision fo capsule of knee joint, arthroscopic
6.8
7.3
17
25
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.6
7.2
170
1097
L04AB04
ATC
adalimumab; parenteral
2.1
7.2
64
307
N02BF02
ATC
pregabalin; oral
1.7
7.2
137
839
M94.8
ICD-10 Finland
Other specified disorders of cartilage
30.1
7.1
9
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
2.3
7.1
52
230
A46
ICD-10 Finland
Erysipelas
1.4
7.1
305
2223
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
3.3
7.1
26
80
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
2.2
7.1
55
250
M92.5
ICD-10 Finland
Juvenile osteochondrosis of tibia and fibula
12.0
7.1
12
10
JAH01
NOMESCO Finland
Laparoscopy
1.8
7.0
98
549
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
4.2
7.0
18
43
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.0
547
4376
M70.6
ICD-10 Finland
Trochanteric bursitis
1.5
7.0
242
1696
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
7.0
132
807
K02.1
ICD-10 Finland
Caries of dentine
1.2
7.0
1614
14616
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
1.7
7.0
126
761
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
2.0
7.0
69
345
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.4
7.0
255
1807
RF220, ,
NOMESCO Finland
2.9
6.9
32
113
J01FA09
ATC
clarithromycin; systemic
1.3
6.9
774
6475
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
1.7
6.9
111
649
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
5.5
6.9
19
35
NG1BM
NOMESCO Finland
Knee and lower leg MRI examination with 3 Tesla magnet
13.8
6.9
11
8
SPAT1360
SPAT
Extensive global examination
1.7
6.9
132
810
Z00.0
ICD-10 Finland
General medical examination
1.3
6.8
441
3432
R07.4
ICD-10 Finland
Chest pain, unspecified
1.3
6.8
616
5020
M08.9
ICD-10 Finland
Juvenile arthritis, unspecified
8.3
6.8
14
17
NHL14
NOMESCO Finland
Shortening or lengthening of achilles tendon
4.1
6.8
18
44
R05
ICPC
Cough
1.3
6.8
546
4383
7176A
ICD-9 Finland
Internal derangement of knee, Loose body in knee
9.3
6.8
13
14
M43.0
ICD-10 Finland
Spondylolysis
2.3
6.8
48
210
G56.2
ICD-10 Finland
Lesion of ulnar nerve
1.8
6.8
91
505
M22.1
ICD-10 Finland
Recurrent subluxation of patella
4.3
6.7
17
40
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
6.7
1227
10825
SFA20
NOMESCO Finland
Two-surface restoration
1.2
6.7
1580
14305
J01DA09
ATC
[U] cefadroxil
1.3
6.7
635
5209
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
2.4
6.6
42
175
RF410, ,
NOMESCO Finland
2.7
6.6
33
122
A01
ICPC
Pain general/multiple sites
1.5
6.6
193
1308
Z3231
NOMESCO Finland
Registered nurse
1.3
6.6
621
5088
NGE10
NOMESCO Finland
Incision or suture of capsule of knee joint
3.4
6.5
23
69
S89.9
ICD-10 Finland
Unspecified injury of lower leg
1.8
6.5
86
474
NH1CM
NOMESCO Finland
Ankle and foot extensive MRI examination with 3 Tesla magnet
10.0
6.5
12
12
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.0
6.5
68
347
ND1AD
NOMESCO Finland
Wrist CT examination
2.9
6.5
29
101
NHE20
NOMESCO Finland
Plastic repair of capsule or ligament of ankle joint with transplant
5.7
6.4
17
30
E8879
ICD-8 Finland
Other and unspecified fall
3.5
6.4
21
60
NHF10
NOMESCO Finland
Synovectomy of ankle, open
70.0
6.4
7
*
Y84
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.2
6.4
24
75
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.2
6.4
52
242
M04AA01
ATC
allopurinol; systemic
1.4
6.3
237
1686
M79.7
ICD-10 Finland
Fibromyalgia
1.9
6.3
77
414
L88
ICPC
Rheumatoid/seropositive arthritis
1.8
6.3
85
472
NHL99
NOMESCO Finland
Other operation on muscle or tendon of ankle or foot
3.6
6.3
20
56
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
1.8
6.3
91
517
RF420, ,
NOMESCO Finland
2.5
6.3
37
149
NH1AA, ,
SPAT
2.0
6.3
68
352
NHT99
NOMESCO Finland
Other operation on ankle or foot
18.0
6.3
9
5
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.4
6.3
286
2109
9345
FHL
Tendon or tendon transplantation
+∞
6.3
6
*
M92.9
ICD-10 Finland
Juvenile osteochondrosis, unspecified
+∞
6.3
6
*
9299
FHL
Other measure in this category
+∞
6.3
6
*
7324B
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of lower extremity, excluding foot[OSTEOCHONDROSIS JUVENILIS TUBEROSITATIS TIBIAE]
+∞
6.3
6
*
72398
ICD-8 Finland
Other diseases of bone, Alii definiti
+∞
6.3
6
*
84300
ICD-8 Finland
Sprains and strains of hip and thigh
26.7
6.2
8
*
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
1.9
6.2
71
374
NG1CM
NOMESCO Finland
Knee and lower leg MRI extensive examination with 3 Tesla magnet
7.0
6.2
14
20
M84.3
ICD-10 Finland
Stress fracture, not elsewhere classified
2.6
6.2
35
138
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.7
6.2
107
640
M22.2
ICD-10 Finland
Patellofemoral disorders
4.0
6.2
17
43
NK4EA
NOMESCO Finland
Joint X-ray examintion with load or wrench not elsewhere classified
3.5
6.2
20
57
M67.8
ICD-10 Finland
Other specified disorders of synovium and tendon
2.7
6.1
32
121
ZZH31
NOMESCO Finland
Bone allograft, small pieces
3.4
6.1
21
62
E883A
ICD-9 Finland
Fall into hole or other opening in surface
1.7
6.1
113
689
M79.0
ICD-10 Finland
Rheumatism, unspecified
1.9
6.1
67
349
72909
ICD-8 Finland
Other diseases of joint, Unspecified
8.6
6.0
12
14
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
2.2
6.0
47
215
D16.2
ICD-10 Finland
Benign neoplasm: Long bones of lower limb
3.5
6.0
20
58

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
131
536
2.51
20.71
1.7
1.7
15470.93
14116.34
e6/l
0.08
99
391
2001
17433
1.45
19.29
4.6
3.9
11.11
10.60
mm/h
0.95
1883
16307
1342
10965
1.41
18.03
2.7
2.5
—
—
—
0
0
478
3236
1.57
16.65
2.2
2.1
—
—
—
0
0
95
399
2.43
14.28
1.6
1.6
—
—
—
0
0
901
7192
1.36
12.69
2.3
2.4
—
—
—
0
0
1334
11312
1.33
12.42
7.8
6.4
—
—
—
0
0
565
4189
1.43
12.29
1.4
1.3
25.90
28.86
iu/ml
0.27
185
1361
2598
24449
1.50
11.79
15.2
12.7
21.66
22.98
mg/l
1.26
2140
19082
1176
9848
1.32
11.76
13.0
12.5
1.22
1.21
inr
0.15
345
2979
538
3991
1.42
11.61
1.3
1.2
8.53
10.84
u/ml
0.51
232
1647
66
264
2.53
11.08
1.7
1.7
50.97
55.83
%
0.42
45
171
116
588
2.01
11.06
1.4
1.4
—
—
—
0
0
79
357
2.25
10.15
1.6
1.4
—
—
—
0
0
1424
12403
1.28
10.05
7.5
6.0
1.98
1.97
e9/l
0.11
1278
11102
1382
12021
1.28
9.75
7.4
6.0
0.59
0.57
e9/l
1.05
1215
10537
54
210
2.60
9.64
1.3
1.4
346254.35
67545.32
e6/l
1.14
31
142
1383
12044
1.28
9.61
7.3
6.0
0.04
0.04
e9/l
0.05
1217
10548
1302
11278
1.27
9.37
7.6
6.1
2.92
2.85
%
0.54
1236
10623
455
3397
1.40
9.32
1.5
1.3
546.02
483.78
titre
0.25
103
667
1344
11708
1.27
9.16
7.7
6.1
28.74
28.52
%
0.29
1278
11071
2360
22064
1.34
9.14
4.6
4.4
1.80
2.04
mu/l
1.54
2188
20549
1260
10909
1.27
8.97
7.7
6.2
0.66
0.68
%
0.73
1187
10255
1326
11554
1.27
8.94
7.3
5.9
56.68
56.78
%
0.12
1264
10918
1303
11344
1.26
8.80
8.2
6.4
8.38
8.50
%
0.67
1241
10699
1416
12464
1.26
8.66
7.7
6.2
0.20
0.19
e9/l
0.42
1258
11062
1768
16000
1.26
8.39
4.2
4.0
—
—
—
0
0
23
59
3.92
8.14
1.5
1.2
44.99
36.62
g/l
1.94
15
35
752
6175
1.29
8.01
2.7
2.5
945.86
3898.83
umol/l
3.87
673
5527
708
5778
1.30
7.89
4.5
4.3
—
—
—
0
0
1501
13414
1.24
7.63
4.9
4.8
6.69
6.66
mmol/l
0.19
1417
12508
674
5491
1.29
7.57
2.3
2.3
—
—
—
0
0
1938
17860
1.24
7.23
8.4
7.3
77.49
76.55
u/l
0.39
1860
16956
2574
24589
1.35
7.05
16.1
14.0
139.62
139.66
mmol/l
0.46
2521
24000
1210
10635
1.23
6.96
6.6
6.9
1.21
1.21
mmol/l
0.08
1034
9120
655
5368
1.28
6.95
1.8
1.8
0.84
1.04
mg/l
2.63
489
4043
2580
24693
1.34
6.67
16.1
14.1
3.97
3.96
mmol/l
0.22
2517
24058
2679
25794
1.39
6.64
13.7
11.6
—
—
—
0
0
1080
9419
1.23
6.59
5.4
5.0
36.04
36.16
g/l
0.29
1015
8823
146
931
1.60
6.54
1.2
1.2
0.29
0.98
u/ml
1.17
13
77
434
3399
1.32
6.44
2.4
2.5
13.78
13.77
umol/l
0.01
406
3183
1313
11720
1.22
6.28
6.7
6.1
10.96
11.32
umol/l
0.65
1255
11144
938
8092
1.23
6.28
3.2
3.3
31.58
34.15
u/l
0.59
898
7701
722
6054
1.25
6.26
3.7
3.5
—
—
—
0
0
656
5441
1.26
6.24
2.9
3.0
1278.77
1223.57
ng/l
0.11
538
4541
1096
9624
1.22
6.15
6.1
6.2
1.21
1.21
mmol/l
0.36
1019
8861
836
7139
1.24
6.13
3.1
2.5
53.42
70.68
u/l
0.91
790
6657
777
6588
1.24
6.08
2.1
2.2
238.98
233.34
u/l
0.05
732
6214
1974
18374
1.22
6.04
3.9
3.8
14.59
14.62
pmol/l
0.15
1826
16959
1631
14902
1.21
6.03
4.1
4.0
273.62
1445.57
e6/l
1.77
26
194
222
1578
1.44
5.98
1.4
1.4
—
—
—
0
0
263
1930
1.40
5.92
4.3
4.3
0.59
0.93
%
1.32
94
636
1514
13759
1.20
5.85
10.1
9.1
4.09
4.06
e9/l
0.25
1338
12106
44
199
2.23
5.79
1.6
1.5
25.44
33.31
%
0.72
28
123
230
1666
1.41
5.59
3.9
2.8
3.86
5.44
e9/l
2.58
192
1417
249
1835
1.39
5.48
4.3
4.3
0.02
0.12
%
3.72
82
542
242
1777
1.39
5.44
4.3
4.1
0.54
0.70
%
0.59
89
556
2294
21779
1.23
5.35
5.6
5.1
39.62
39.27
mmol/mol
0.68
2157
20496
393
3133
1.29
5.09
2.4
2.5
2.36
2.36
g/l
0.02
360
2917
234
1745
1.37
4.81
4.2
4.4
0.13
0.50
%
0.73
69
451
147
1010
1.48
4.77
1.1
1.1
—
—
—
0
0
2829
27676
1.46
4.71
21.7
18.3
30.26
30.26
pg
0.07
2795
27359
2827
27655
1.46
4.68
21.8
18.4
253.50
252.40
e9/l
0.40
2764
27050
2829
27680
1.46
4.66
21.8
18.4
4.57
4.58
e12/l
0.85
2763
27016
2829
27681
1.46
4.65
21.8
18.4
6.82
6.70
e9/l
1.56
2761
27008
2828
27673
1.46
4.61
21.7
18.3
90.60
90.54
fl
0.30
2793
27358
551
4627
1.23
4.58
2.8
2.5
5.24
5.83
e6/l
0.56
500
4160
929
8211
1.19
4.54
3.9
3.3
112.15
48.76
ng/l
0.43
611
5141
249
1894
1.34
4.52
3.0
2.6
10.13
10.56
g/l
1.07
220
1753
2828
27690
1.44
4.41
22.0
18.5
137.38
137.87
g/l
1.05
2794
27364
361
2907
1.28
4.32
2.6
2.6
23.28
23.62
%
0.17
302
2508
1849
17377
1.17
4.08
3.3
3.1
48.71
47.04
u/l
0.37
1766
16473
356
2884
1.27
4.06
6.3
6.5
1.05
1.04
mmol/l
0.20
336
2696
271
2121
1.31
4.05
2.6
2.3
0.23
0.22
g/l
0.61
248
1996
1027
9225
1.17
4.05
2.4
2.2
75.09
74.93
nmol/l
0.06
927
8453
2690
26177
1.29
4.03
11.2
9.6
28.11
27.98
u/l
0.13
2615
25429
341
2758
1.27
3.95
1.8
1.7
—
—
—
0
0
2507
24217
1.23
3.91
4.2
4.1
4.67
4.70
mmol/l
0.83
2368
22891
2819
27638
1.39
3.83
21.9
18.5
40.79
41.03
%
0.59
2661
26133
195
1477
1.34
3.69
2.1
1.7
1.24
1.34
g/l
0.22
176
1374
515
4387
1.21
3.69
3.3
2.8
564.21
553.19
mosm/kgh2o
0.49
447
3777
153
1116
1.39
3.66
3.4
2.7
0.15
0.22
e6/l
0.85
148
1082
495
4204
1.21
3.65
3.1
3.5
381.91
499.19
ng/l
0.29
360
3017
526
4494
1.21
3.65
1.6
1.6
16027515.41
37292522.96
pmol/l
0.61
443
3848
1168
10671
1.16
3.58
10.7
9.0
0.00
0.00
e9/l
1.07
967
8758
26
118
2.21
3.51
1.3
1.5
—
—
—
0
0
72
455
1.60
3.50
4.7
3.6
3.96
4.05
e9/l
0.18
72
455
2531
24530
1.21
3.48
4.6
4.4
2.79
2.82
mmol/l
0.88
2379
23053
1156
10572
1.15
3.47
2.9
2.8
111.64
121.05
ug/l
0.98
1090
9919
746
6601
1.17
3.46
4.0
3.9
9.00
9.00
mg/mmol
0.00
507
4328
714
6296
1.18
3.45
3.3
3.3
322.01
302.84
mg/l
0.04
487
4173
133
959
1.40
3.43
3.0
3.6
24.58
25.20
mmol/l
1.14
124
924
10
22
4.56
3.42
1.6
1.1
—
—
—
0
0
2488
24085
1.20
3.40
4.2
4.0
1.39
1.43
mmol/l
4.07
2343
22655
947
8551
1.16
3.36
1.9
1.9
95.40
96.10
pmol/l
0.19
515
4684
1739
16392
1.15
3.32
3.7
3.4
—
—
—
0
0
73
471
1.56
3.28
4.9
3.8
57.10
56.70
%
0.12
73
471
790
7063
1.16
3.18
3.3
3.3
8.00
8.16
mmol/l
0.45
688
6096
40
222
1.81
3.15
2.8
2.6
1.50
1.70
g/24h
0.11
22
120
2233
21463
1.16
3.13
17.0
15.0
14.75
14.79
%
0.05
2190
21078
2395
23148
1.18
3.13
4.4
4.1
5.90
5.88
mmol/l
0.39
2226
21460
17
67
2.55
3.12
3.9
2.4
144.17
173.66
e6/l
0.33
12
41
183
1413
1.31
3.08
3.8
3.6
5.14
5.15
kpa
0.03
169
1359
181
1397
1.31
3.05
3.8
3.6
7.41
7.41
ph
0.02
25
168
8
16
5.01
3.05
5.1
1.8
2.92
3.87
mg/l
—
8
16
11
31
3.56
2.99
1.3
1.3
1.39
1.61
mmol/l
—
5
19
1247
11550
1.14
2.98
3.6
3.3
0.00
0.00
estimate
1.22
238
2123
800
7192
1.15
2.96
3.2
3.3
2.34
2.35
mmol/l
0.74
715
6456
21
94
2.24
2.96
1.7
1.7
—
—
—
0
0
43
251
1.72
2.88
1.1
1.5
—
26.08
—
0
13
413
3536
1.20
2.80
1.7
1.7
1200.78
1161.72
nmol/l
0.29
320
2729
267
2190
1.24
2.78
2.8
2.5
35.84
61.86
u/l
0.64
224
1897
128
953
1.36
2.78
1.3
1.2
—
—
—
0
0
170
1329
1.30
2.65
7.6
7.5
24.65
24.47
mmol/l
0.19
159
1267
282
2340
1.23
2.65
2.4
2.2
12.64
13.28
nmol/l
0.75
260
2147
662
5915
1.15
2.64
4.2
4.0
93.15
91.77
%
0.78
646
5769
11
35
3.15
2.64
1.0
1.5
—
—
—
0
0
697
6253
1.15
2.63
3.9
4.1
7.40
7.40
ph
0.02
154
1233
532
4681
1.17
2.61
1.5
1.5
19.98
20.18
nmol/l
0.12
454
4104
683
6122
1.15
2.61
4.1
3.6
0.00
0.00
estimate
1.54
240
2147
1226
11427
1.12
2.53
4.8
4.5
0.00
0.00
estimate
0.42
246
2241
1229
11461
1.12
2.51
3.7
3.3
0.00
0.00
estimate
0.99
256
2314
2396
23265
1.15
2.48
3.8
3.7
1.38
1.33
mmol/l
1.81
2247
21773
97
705
1.39
2.48
1.4
1.3
61.43
89.86
titre
—
7
69
416
3604
1.18
2.47
3.9
3.7
0.82
0.82
mmol/l
0.29
392
3427
559
4963
1.16
2.43
3.9
3.6
1.02
1.02
kg/l
0.22
88
691
190
1526
1.26
2.41
1.2
1.3
45.65
53.65
au/ml
0.21
11
88
742
6737
1.14
2.32
3.4
3.1
93.36
119.43
e6/l
0.21
594
5167
265
2219
1.21
2.30
3.7
2.8
1.73
1.76
%
0.22
233
1996
240
1992
1.22
2.28
8.6
8.3
9.18
8.96
mmol/l
0.19
231
1913
38
231
1.65
2.26
3.8
4.1
—
—
—
0
0
237
1967
1.22
2.25
4.0
4.2
1.43
1.89
mmol/l
1.33
194
1646
301
2557
1.20
2.25
1.4
1.3
—
—
—
0
0
1005
9312
1.12
2.23
3.3
3.1
5.95
5.82
ph
0.78
75
900
133
1034
1.30
2.21
3.7
3.6
—
—
—
0
0
34
202
1.69
2.21
2.7
3.5
57.17
55.56
%
0.16
29
179
662
5989
1.14
2.18
2.9
2.7
—
—
—
0
0
203
1665
1.24
2.17
2.2
2.4
16.82
24.21
au/ml
0.84
17
140
610
5493
1.14
2.16
2.5
2.1
2.93
2.86
mg/l
0.34
531
4711
173
1395
1.25
2.15
1.3
1.2
—
—
—
0
0
21
108
1.95
2.15
1.0
1.1
—
—
—
0
0
998
9265
1.12
2.13
2.1
2.0
—
—
—
0
0
236
1973
1.21
2.10
4.0
4.1
5.81
5.85
kpa
0.22
223
1914
34
206
1.66
2.07
1.2
1.2
—
—
—
0
0
170
1378
1.25
2.04
5.5
5.4
—
—
—
0
0
6
15
4.01
2.04
1.0
1.3
—
—
—
0
0
674
6134
1.13
2.01
3.1
3.0
0.27
0.40
e6/l
1.50
537
4636
283
2425
1.18
1.95
7.6
8.5
1.22
0.98
mmol/l
0.46
229
1924
98
747
1.32
1.92
1.9
1.6
0.23
0.24
g/l
0.25
90
705
56
389
1.45
1.90
3.2
3.3
7.16
7.39
mmol/l
0.28
56
381
856
7929
1.11
1.87
3.8
3.5
61.29
84.59
e6/l
0.63
635
5553
283
2436
1.18
1.86
7.6
8.5
5.09
5.11
kpa
0.09
266
2339
283
2437
1.18
1.85
7.5
8.4
12.38
12.56
kpa
0.22
268
2341
39
587
0.66
1.84
1.5
1.5
—
—
—
0
0
193
1606
1.22
1.84
3.0
2.7
66.20
66.93
g/l
0.61
176
1490
101
779
1.31
1.83
1.9
1.6
1.19
1.18
g/l
0.04
92
736
38
572
0.66
1.80
1.5
1.4
—
—
—
0
0
7
23
3.05
1.80
1.0
1.0
—
—
—
0
0
54
379
1.43
1.76
3.3
2.8
—
—
—
0
0
38
569
0.66
1.76
1.5
1.4
—
—
—
0
0
6
18
3.34
1.74
1.0
1.3
—
—
—
0
0
356
3138
1.15
1.74
1.3
1.2
—
—
—
0
0
113
892
1.28
1.73
1.6
1.5
9.04
9.09
u/l
0.01
87
735
116
919
1.27
1.73
1.5
1.8
1.54
1.53
g/l
0.05
102
803
306
2673
1.16
1.69
3.2
2.8
9.18
7.83
umol/l
0.41
263
2320
193
1623
1.20
1.67
3.3
2.8
69.04
71.48
e9/l
0.43
153
1224
193
1627
1.20
1.63
1.5
1.3
203.71
240.35
u/ml
0.33
183
1507
89
687
1.30
1.63
7.1
3.8
1.34
1.46
mg/l
1.04
82
643
113
902
1.26
1.60
4.0
3.7
24.72
24.81
mmol/l
0.11
105
850
74
558
1.33
1.60
1.6
1.5
—
17.22
—
0
13
161
1339
1.21
1.58
1.6
1.4
26.21
25.98
iu/l
0.03
144
1133
201
1708
1.19
1.57
3.8
3.8
1.22
1.23
mmol/l
0.58
185
1494
362
3223
1.14
1.55
1.6
1.6
—
—
—
0
0
34
224
1.52
1.54
2.9
2.7
—
—
—
0
0
568
5201
1.11
1.53
3.4
3.3
—
—
—
0
0
5
15
3.34
1.52
1.8
1.4
21.80
17.00
%
—
5
10
20
115
1.74
1.52
3.0
2.9
7.41
7.43
ph
—
9
39
7
27
2.60
1.51
1.1
2.1
91.43
118.87
ng/l
—
7
27
126
1029
1.23
1.49
1.7
1.8
38.17
38.86
nmol/l
0.12
120
999
18
101
1.79
1.48
1.1
1.1
—
—
—
0
0
74
566
1.32
1.48
1.2
1.2
—
—
—
0
0
72
549
1.32
1.47
1.7
1.5
—
—
—
0
0
41
285
1.44
1.45
1.7
1.5
—
—
—
0
0
7
28
2.50
1.45
1.3
1.1
—
—
—
0
0
57
421
1.36
1.44
3.2
3.2
1.52
1.52
mmol/l
0.03
57
409
58
430
1.36
1.43
1.1
1.1
124.93
1227.73
iu/ml
0.49
14
111
39
270
1.45
1.41
1.4
1.4
347.97
345.72
pmol/l
0.01
32
239
349
3125
1.13
1.38
3.1
2.4
135.94
130.17
ug/g
0.09
283
2532
13
67
1.94
1.38
1.8
1.9
—
—
—
0
0
9
41
2.20
1.37
2.2
2.1
—
—
—
0
0
6
23
2.61
1.36
3.3
3.1
—
—
—
0
0
151
1269
1.20
1.36
2.8
3.5
133.37
131.57
g/l
0.40
143
1240
5
17
2.94
1.36
1.0
1.2
—
—
—
0
0
54
400
1.36
1.35
1.3
1.4
—
—
—
0
0
32
215
1.49
1.35
1.4
1.5
1.06
0.97
g/l
1.00
32
215
154
1300
1.19
1.33
2.8
2.2
—
—
—
0
0
696
6484
1.10
1.33
3.3
3.0
—
—
—
0
0
643
5970
1.10
1.32
7.7
6.7
—
—
—
0
0
27
176
1.54
1.31
1.4
1.4
79.26
78.30
umol/l
0.07
27
176
26
168
1.55
1.31
1.1
1.1
1.05
1.05
ratio
—
10
62
653
6071
1.10
1.30
3.1
3.0
—
—
—
0
0
31
209
1.49
1.30
1.4
1.2
—
211.25
—
0
8
31
209
1.49
1.30
1.5
1.2
284.00
180.71
titre
—
5
42
173
1480
1.18
1.29
3.5
3.5
4.61
4.54
pmol/l
0.49
152
1334
24
153
1.57
1.28
1.0
1.0
—
—
—
0
0
538
4969
1.10
1.24
1.6
1.4
2.41
2.39
g/l
0.06
361
3167
75
941
0.79
1.21
1.7
1.7
—
—
—
0
0
378
3434
1.12
1.20
2.1
2.2
29.50
29.84
s
0.67
365
3332
63
488
1.30
1.20
2.9
2.2
128.00
132.67
g/l
0.87
46
357
85
684
1.25
1.19
1.0
1.1
2.49
6.90
u/ml
—
7
102
233
2055
1.15
1.19
4.2
4.1
—
—
—
0
0
44
324
1.36
1.17
1.8
1.7
—
—
—
0
0
188
1635
1.16
1.17
3.7
3.4
4.85
4.68
kpa
0.50
179
1583
72
570
1.27
1.16
1.6
1.5
1590.70
1325.26
e6/l
0.10
63
462
72
570
1.27
1.16
1.6
1.5
27.37
27.76
e6/l
0.01
60
437
36
257
1.41
1.15
1.2
1.1
—
—
—
0
0
5
20
2.50
1.15
1.0
1.0
—
9.14
—
0
7
26
174
1.50
1.15
1.3
1.3
—
—
—
0
0
15
87
1.73
1.15
1.3
1.1
—
—
—
0
0
19
118
1.61
1.14
1.8
1.5
—
—
—
0
0
103
852
1.22
1.14
4.8
6.1
1.93
1.68
%
0.90
98
800
311
2804
1.12
1.13
1.5
1.5
—
—
—
0
0
80
645
1.25
1.12
1.3
1.4
427.22
288.22
ug/g
0.75
39
355
19
119
1.60
1.11
1.3
1.6
2.65
3.64
nmol/l
0.21
14
97
65
513
1.27
1.09
1.6
1.5
117.45
115.15
u/ml
0.07
17
94
66
522
1.27
1.09
1.6
1.5
—
—
—
0
0
59
460
1.29
1.09
3.2
2.5
16.27
16.69
%
0.37
31
233
8
41
1.95
1.08
1.3
1.1
—
—
—
0
0
248
2213
1.13
1.08
2.7
2.1
352.31
372.25
nmol/l
0.74
232
2045
27
185
1.46
1.08
1.1
1.3
1.49
1.55
g/l
0.75
27
185
27
185
1.46
1.08
1.3
1.3
2.76
0.97
u/ml
0.29
17
99
237
2109
1.13
1.08
1.4
1.5
—
—
—
0
0
86
703
1.23
1.07
5.2
6.9
1.25
1.29
mmol/l
0.19
73
614
36
261
1.38
1.07
2.5
2.8
—
—
—
0
0
92
758
1.22
1.07
2.6
2.5
361.38
480.94
ug/l
0.45
87
716
51
392
1.31
1.05
5.4
3.4
—
—
—
0
0
25
170
1.47
1.04
1.5
1.5
5.98
6.34
mmol/l
0.26
19
157
2219
21758
1.08
1.04
18.2
15.7
333.54
333.50
g/l
0.07
2200
21604
101
843
1.21
1.04
4.9
6.2
0.91
0.90
%
0.03
96
792
5
22
2.27
1.03
1.0
1.0
—
—
—
0
0
8
151
0.53
1.02
1.0
1.2
—
—
—
0
0
78
635
1.23
1.02
2.8
3.1
—
—
—
0
0
48
368
1.31
1.02
1.1
1.1
1.52
1.49
g/l
0.21
40
341
62
492
1.27
1.01
7.6
4.3
2.72
2.48
mmol/l
0.23
43
320
46
351
1.32
1.01
1.1
1.2
—
—
—
0
0
26
180
1.45
1.00
1.7
1.5
—
—
—
0
0
62
493
1.26
1.00
7.6
4.4
4.92
5.01
kpa
0.45
62
485
62
493
1.26
1.00
7.6
4.4
8.83
8.75
kpa
0.17
62
484
244
2188
1.13
1.00
8.3
9.0
95.31
95.79
%
0.42
231
2118
11
61
1.81
0.98
1.0
1.1
—
—
—
0
0
11
61
1.81
0.98
1.0
1.1
—
—
—
0
0
11
61
1.81
0.98
1.0
1.1
—
—
—
0
0
60
477
1.26
0.97
6.0
8.6
10.98
11.41
mmol/l
0.59
54
431
60
478
1.26
0.96
6.0
8.6
105.02
105.36
mmol/l
0.26
54
432
29
207
1.40
0.96
1.5
1.5
2595.74
1997.29
e6/l
0.14
19
144
115
980
1.18
0.96
2.7
3.1
1.45
1.30
%
0.79
115
975
26
183
1.42
0.93
1.9
1.5
—
—
—
0
0
227
2037
1.12
0.93
8.4
9.3
122.28
123.93
g/l
0.57
220
1986
77
634
1.22
0.93
1.2
1.2
12.52
9.27
u/ml
0.17
11
98
98
828
1.19
0.91
1.8
2.1
3.04
1.75
ug/l
0.40
84
757
6
28
2.15
0.91
3.8
3.0
—
—
—
0
0
38
287
1.33
0.91
1.2
1.4
160.82
201.47
pmol/l
0.60
38
287
21
143
1.47
0.89
1.2
1.4
—
—
—
0
0
24
168
1.43
0.89
1.0
1.2
—
—
—
0
0
24
169
1.42
0.87
1.3
1.1
—
—
—
0
0
290
2651
1.10
0.86
4.2
4.1
30.48
31.33
%
0.63
200
1932
38
290
1.31
0.86
1.2
1.3
—
—
—
0
0
262
2875
0.90
0.86
1.7
1.7
—
—
—
0
0
315
2893
1.10
0.86
1.3
1.3
—
—
—
0
0
81
679
1.20
0.84
1.2
1.2
31.64
48.99
u/ml
—
5
39
69
571
1.21
0.82
1.3
1.3
3.50
3.76
mmol/l
2.01
69
534
75
626
1.20
0.82
1.2
1.2
1.27
2.36
u/ml
—
6
61
22
306
0.72
0.80
2.5
3.7
16.95
28.54
u/ml
1.54
22
299
120
1045
1.15
0.80
2.1
2.3
—
—
—
0
0
46
365
1.26
0.80
1.1
1.2
13.88
44.17
u/l
2.50
35
313
53
428
1.24
0.79
5.3
3.2
—
—
—
0
0
219
1984
1.11
0.79
3.9
4.3
41.04
17.47
ug/l
0.35
184
1595
330
3051
1.09
0.79
1.4
1.4
—
—
—
0
0
17
114
1.49
0.79
1.0
1.2
136.79
196.93
iu/ml
1.01
17
114
127
1112
1.15
0.79
2.6
2.2
3331.81
5212.02
u/l
0.53
44
429
26
190
1.37
0.79
3.9
2.2
—
—
—
0
0
29
216
1.35
0.78
2.9
2.6
—
—
—
0
0
11
66
1.67
0.78
1.2
1.2
—
—
—
0
0
66
548
1.21
0.77
1.4
1.3
—
—
—
0
0
6
34
1.77
0.76
1.2
1.0
—
—
—
0
0
25
183
1.37
0.75
1.4
1.4
13456.15
72336.90
e6/l
1.62
13
105
177
1591
1.12
0.75
3.1
2.8
209.05
162.84
ng/l
0.68
155
1442
70
587
1.20
0.74
7.0
4.3
7.42
7.42
ph
0.47
64
524
157
1402
1.13
0.74
2.5
2.5
—
—
—
0
0
38
298
1.28
0.73
1.1
1.4
0.61
0.60
nmol/l
0.07
38
285
59
489
1.21
0.71
7.4
3.6
—
—
—
0
0
46
372
1.24
0.70
1.6
1.3
—
—
—
0
0
34
265
1.29
0.70
1.4
1.3
0.32
0.37
g/l
0.41
19
178
34
265
1.29
0.70
1.4
1.3
2.41
2.91
g/l
0.67
19
180
9
58
1.55
0.69
3.2
2.9
—
—
—
0
0
109
956
1.15
0.69
1.2
1.2
—
—
—
0
0
132
1173
1.13
0.69
10.1
11.7
—
—
—
0
0
27
204
1.33
0.69
2.6
3.1
—
—
—
0
0
398
3735
1.08
0.68
2.5
2.7
1.06
1.09
e6/l
0.06
225
2070
5
27
1.85
0.68
20.2
7.7
—
—
—
0
0
12
77
1.56
0.68
1.2
1.1
0.23
2.01
u/ml
—
7
43
81
695
1.17
0.68
1.1
1.2
—
—
—
0
0
7
42
1.67
0.68
1.1
1.2
0.01
0.84
u/ml
—
7
42
88
761
1.16
0.67
2.4
2.5
—
—
—
0
0
21
153
1.38
0.67
1.7
3.3
—
—
—
0
0
111
1257
0.88
0.66
1.1
1.1
—
—
—
0
0
43
348
1.24
0.66
1.9
2.0
1.53
1.68
mmol/l
0.83
43
341
34
268
1.27
0.65
1.5
1.3
—
—
—
0
0
8
131
0.61
0.63
1.0
1.3
26.50
31.12
nmol/l
—
8
110
18
129
1.40
0.63
1.9
3.0
1216.00
1155.87
u/ml
0.05
18
129
1010
9776
1.05
0.63
2.7
2.6
—
—
—
0
0
206
1890
1.10
0.62
1.5
1.4
—
—
—
0
0
8
51
1.57
0.60
1.4
1.2
—
—
—
0
0
64
546
1.18
0.60
4.9
3.2
2.09
2.60
ratio
—
5
48
0
22
0.00
0.59
0.0
1.4
—
—
—
0
0
394
3720
1.07
0.59
2.9
3.0
2.43
2.44
mmol/l
0.19
350
3284
39
476
0.82
0.59
2.2
3.5
—
—
—
0
0
16
114
1.41
0.58
1.3
1.4
162.44
166.87
mmol/24h
0.11
16
114
0
23
0.00
0.58
0.0
1.8
—
41.96
—
0
23
34
273
1.25
0.58
1.1
1.4
—
—
—
0
0
15
106
1.42
0.57
1.7
1.5
25.40
28.53
umol/l
0.74
15
101
18
132
1.37
0.57
1.3
1.4
130.79
139.14
nmol/l
0.52
18
132
33
265
1.25
0.56
1.5
1.3
6.18
6.64
g/l
0.39
18
181
162
1480
1.10
0.55
4.1
4.3
93.83
85.82
ng/l
0.65
142
1332
113
1013
1.12
0.55
1.6
1.7
—
—
—
0
0
209
1934
1.09
0.54
7.0
8.1
1.47
1.37
mmol/l
0.42
204
1883
33
267
1.24
0.54
1.0
1.3
—
—
nmol/l
—
0
0
452
4303
1.06
0.53
1.6
1.6
—
—
—
0
0
21
160
1.31
0.53
2.0
1.9
0.85
2.03
u/field
1.36
13
72
61
525
1.17
0.53
3.1
2.0
0.73
0.84
nmol/l
0.82
47
443
56
479
1.17
0.53
3.6
3.4
22.36
25.02
mg/l
0.21
32
302
29
232
1.25
0.52
1.3
1.4
—
—
—
0
0
21
161
1.31
0.51
1.4
1.5
—
—
—
0
0
11
75
1.47
0.50
1.5
1.4
97.63
92.71
nmol/24h
0.05
11
75
6
41
1.46
0.50
1.2
1.1
—
—
—
0
0
62
538
1.16
0.50
2.5
2.4
136.13
131.56
ug/min
0.02
38
347
50
427
1.17
0.49
1.6
1.6
0.69
0.81
g/l
0.55
32
324
7
45
1.56
0.49
1.1
1.9
—
—
—
0
0
45
381
1.18
0.48
1.0
1.1
8.78
5.24
u/ml
0.33
19
149
20
154
1.30
0.48
3.3
2.2
—
—
—
0
0
583
5610
1.05
0.47
1.3
1.3
2.18
1.85
u/ml
0.24
173
1548
14
102
1.37
0.47
1.1
1.1
—
—
—
0
0
83
739
1.13
0.47
3.5
3.8
2737.17
2043.26
u/ml
0.11
71
631
64
561
1.14
0.46
5.0
3.3
36.02
63.54
mg/l
1.56
53
453
64
561
1.14
0.46
5.0
3.3
40.19
49.31
mg/l
0.22
53
453
5
85
0.59
0.45
1.2
1.5
13.02
15.29
pmol/l
—
5
73
14
103
1.36
0.45
1.0
1.0
—
—
—
0
0
46
394
1.17
0.45
1.2
1.4
25.77
22.58
u/l
0.26
38
324
93
1031
0.90
0.44
2.1
2.4
—
—
—
0
0
54
470
1.15
0.43
4.7
4.1
—
—
—
0
0
846
8226
1.04
0.43
4.3
4.2
1.83
2.23
ug/l
2.05
764
7489
189
1764
1.08
0.43
3.4
3.3
—
—
—
0
0
8
56
1.43
0.42
1.0
1.4
—
—
—
0
0
5
32
1.56
0.42
1.0
1.0
—
—
—
0
0
75
670
1.12
0.42
1.1
1.1
—
—
—
0
0
8
58
1.38
0.41
1.1
1.1
—
—
—
0
0
5
33
1.52
0.41
1.8
1.2
2.90
5.06
nmol/l
—
5
33
0
15
0.00
0.41
0.0
1.9
—
1.80
—
0
15
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
39
455
0.86
0.40
1.2
1.2
—
—
—
0
0
0
17
0.00
0.40
0.0
1.4
—
—
—
0
0
5
34
1.47
0.40
1.2
1.6
—
—
—
0
0
8
60
1.33
0.40
2.1
1.4
2.63
2.75
%
—
8
52
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
0
18
0.00
0.40
0.0
1.0
—
—
—
0
0
83
917
0.90
0.39
1.4
1.3
211.11
216.95
miu/ml
0.04
27
432
14
106
1.32
0.39
4.1
5.2
—
—
—
0
0
639
6195
1.04
0.38
1.7
1.7
1.50
1.42
mmol/l
0.97
544
5312
214
2017
1.07
0.38
4.1
3.6
—
—
—
0
0
18
142
1.27
0.38
2.7
3.4
—
—
—
0
0
9
66
1.36
0.38
1.6
1.5
—
—
—
0
0
38
440
0.86
0.37
1.4
1.3
—
—
—
0
0
121
1119
1.08
0.36
10.0
11.4
24.15
24.30
mmol/l
0.19
114
1098
72
649
1.11
0.36
5.7
4.2
3.88
3.91
mmol/l
0.24
72
642
24
198
1.21
0.36
1.1
1.1
—
—
—
0
0
5
76
0.66
0.35
1.2
1.3
—
—
—
0
0
6
42
1.43
0.35
1.2
1.1
—
—
—
0
0
6
42
1.43
0.35
1.3
1.5
—
—
—
0
0
366
3518
1.05
0.34
2.9
2.8
3.15
2.26
e6/l
0.89
190
1870
26
219
1.19
0.33
1.1
1.1
255.35
285.80
mg/l
1.87
20
203
10
74
1.35
0.32
2.2
2.2
—
—
—
0
0
41
360
1.14
0.32
1.6
1.5
—
—
—
0
0
193
1828
1.06
0.32
9.1
9.7
—
—
—
0
0
64
579
1.11
0.31
2.5
3.2
—
—
—
0
0
12
92
1.31
0.31
1.8
1.4
—
—
—
0
0
29
337
0.86
0.31
1.4
1.4
2.34
3.27
ug/l
1.10
23
303
38
333
1.14
0.31
2.4
2.2
5.26
5.59
umol/l
0.12
28
243
282
2702
1.05
0.31
1.5
1.4
—
—
—
0
0
7
53
1.32
0.30
3.4
2.5
—
—
—
0
0
7
100
0.70
0.30
1.3
1.5
—
—
—
0
0
16
129
1.24
0.30
1.8
1.4
14.63
13.48
u/l
0.19
16
123
15
185
0.81
0.29
1.9
3.2
12.68
10.95
%
0.63
15
185
19
158
1.20
0.28
1.1
1.1
—
—
—
0
0
67
613
1.10
0.28
1.9
1.9
3.84
5.04
iu/l
0.67
24
234
12
94
1.28
0.28
1.1
1.2
—
0.06
g/l
—
0
7
11
85
1.30
0.28
1.5
1.3
—
—
—
0
0
725
7095
1.03
0.27
1.5
1.5
—
—
—
0
0
63
576
1.10
0.27
1.3
1.3
224.05
260.76
u/ml
0.67
42
354
11
86
1.28
0.26
2.1
1.6
—
—
—
0
0
45
405
1.11
0.26
1.2
1.2
—
—
—
0
0
9
72
1.25
0.25
1.4
1.5
—
—
—
0
0
42
466
0.90
0.25
1.2
1.2
—
—
—
0
0
21
179
1.17
0.25
1.2
1.0
—
—
—
0
0
123
1301
0.94
0.24
1.9
2.2
—
—
—
0
0
91
851
1.07
0.24
5.4
4.7
—
—
—
0
0
22
189
1.17
0.24
1.2
1.1
—
—
—
0
0
87
813
1.07
0.24
3.5
3.3
0.28
0.35
g/l
0.38
43
373
549
5366
1.03
0.23
2.0
1.9
—
—
—
0
0
5
40
1.25
0.22
1.2
1.5
2.72
831258.45
nmol/l
—
5
32
7
95
0.74
0.22
1.1
1.2
—
—
—
0
0
29
257
1.13
0.22
1.8
1.7
—
—
—
0
0
116
1099
1.06
0.22
1.6
1.6
264.70
295.46
mu/l
0.78
108
998
5
42
1.19
0.21
1.0
1.2
20.34
86.16
ng/l
—
5
29
0
10
0.00
0.21
0.0
2.0
—
—
—
0
0
0
12
0.00
0.21
0.0
1.0
—
—
—
0
0
0
12
0.00
0.21
0.0
2.0
—
—
—
0
0
6
49
1.22
0.20
2.2
1.3
—
—
—
0
0
6
49
1.22
0.20
2.2
1.3
—
—
—
0
0
6
49
1.22
0.20
2.2
1.3
—
—
—
0
0
15
176
0.85
0.20
2.8
2.3
630.67
645.59
ml
—
9
120
35
317
1.11
0.19
2.5
2.7
—
—
—
0
0
29
323
0.90
0.19
2.4
2.4
—
—
—
0
0
32
354
0.90
0.19
1.0
1.0
0.04
0.34
u/ml
—
7
101
209
2019
1.04
0.19
1.2
1.2
—
—
—
0
0
104
988
1.05
0.19
3.9
3.2
—
—
—
0
0
20
175
1.14
0.18
1.2
1.1
—
—
—
0
0
55
590
0.93
0.18
1.5
1.3
—
—
—
0
0
7
59
1.19
0.18
2.1
1.4
15.00
31.13
%
—
7
54
46
497
0.92
0.18
1.2
1.1
—
—
—
0
0
7
61
1.15
0.17
1.9
2.2
15.53
16.41
umol/l
—
7
61
71
669
1.06
0.17
2.2
2.2
10.19
10.33
g/l
0.08
60
612
8
68
1.18
0.16
2.1
1.5
62.75
56.14
%
—
8
57
117
1221
0.96
0.16
1.9
2.4
—
—
—
0
0
8
69
1.16
0.16
1.5
2.1
—
—
—
0
0
179
1731
1.04
0.16
2.7
2.3
14.16
8.24
ug/l
0.75
157
1560
51
545
0.93
0.16
2.0
2.2
—
—
—
0
0
8
73
1.10
0.15
15.1
12.7
—
—
—
0
0
10
83
1.21
0.15
7.2
1.4
—
—
—
0
0
42
451
0.93
0.15
1.1
1.1
—
10.61
—
0
39
128
1328
0.96
0.14
1.9
2.3
—
—
—
0
0
7
90
0.78
0.14
1.7
2.8
—
—
—
0
0
7
90
0.78
0.14
1.0
1.0
—
—
—
0
0
477
4850
0.98
0.14
2.8
2.7
0.64
0.70
ug/l
0.98
284
2924
10
118
0.85
0.14
1.0
1.2
—
—
—
0
0
8
98
0.82
0.13
1.0
1.2
—
—
—
0
0
127
1313
0.97
0.13
1.9
2.3
—
—
—
0
0
128
1323
0.97
0.12
1.9
2.1
—
—
—
0
0
30
324
0.93
0.12
2.1
1.8
—
—
—
0
0
47
498
0.94
0.12
1.0
1.1
2.33
1.91
u/ml
0.13
25
255
80
767
1.04
0.12
10.6
8.8
—
—
—
0
0
47
497
0.94
0.11
1.2
1.1
—
—
—
0
0
11
95
1.16
0.11
3.3
2.8
—
—
—
0
0
11
95
1.16
0.11
3.5
2.0
—
—
—
0
0
16
143
1.12
0.11
1.2
1.2
—
—
—
0
0
318
3233
0.98
0.10
1.3
1.3
—
—
—
0
0
48
456
1.05
0.10
1.1
1.1
—
—
—
0
0
176
1720
1.02
0.10
1.2
1.2
107.48
152.90
iu/ml
1.07
74
648
65
676
0.96
0.09
1.4
1.6
—
—
—
0
0
44
419
1.05
0.09
1.0
1.1
1.01
4.06
u/ml
3.55
25
196
6
55
1.09
0.09
3.0
2.2
—
—
—
0
0
37
390
0.95
0.08
2.9
1.6
—
—
—
0
0
15
136
1.10
0.08
1.7
1.4
15.99
26.36
umol/l
1.08
15
128
12
107
1.12
0.08
1.9
2.1
37.40
216.23
ug/min
—
5
26
5
64
0.78
0.08
1.4
2.2
—
—
—
0
0
7
68
1.03
0.07
1.1
1.0
—
—
—
0
0
73
708
1.03
0.07
1.2
1.1
—
—
—
0
0
195
1918
1.02
0.07
1.4
1.4
—
—
—
0
0
19
204
0.93
0.07
16.9
13.6
674.63
823.26
nmol/l
0.93
19
197
10
89
1.12
0.06
3.5
2.6
—
—
—
0
0
29
304
0.95
0.05
1.2
1.2
—
—
—
0
0
285
2822
1.01
0.05
1.6
1.7
—
—
—
0
0
29
303
0.96
0.05
2.4
3.0
0.84
0.83
nmol/l
0.03
19
234
12
110
1.09
0.05
2.4
2.6
—
—
—
0
0
16
171
0.94
0.05
1.0
1.0
0.55
1.00
u/ml
—
5
44
11
120
0.92
0.05
1.0
1.2
1968.09
1539.55
miu/ml
0.58
11
120
21
199
1.06
0.04
1.3
1.4
1.98
1.98
mmol/l
0.00
21
187
13
140
0.93
0.04
2.5
2.2
528.43
503.04
min
—
7
104
58
566
1.03
0.04
2.4
2.1
37.48
37.92
g/l
0.21
47
510
57
583
0.98
0.03
1.1
1.1
4.95
2.80
u/ml
0.59
33
299
87
884
0.98
0.03
2.3
3.3
—
—
—
0
0
16
169
0.95
0.03
1.1
1.0
—
—
—
0
0
17
179
0.95
0.03
1.5
1.5
—
—
—
0
0
20
191
1.05
0.03
1.1
1.2
—
—
—
0
0
12
112
1.07
0.03
1.1
1.2
—
—
—
0
0
24
231
1.04
0.02
7.4
4.9
346.68
86.91
u/ml
—
9
64
19
182
1.04
0.02
1.6
1.5
—
—
—
0
0
43
422
1.02
0.01
1.2
1.2
3.47
4.71
u/ml
0.44
15
188
50
508
0.98
0.01
1.1
1.1
1.19
1.28
u/ml
0.05
22
222
11
116
0.95
0.00
2.1
2.4
—
—
—
0
0
157
1563
1.00
0.00
1.2
1.2
—
—
—
0
0
22
226
0.97
0.00
1.1
1.1
—
—
—
0
0
24
234
1.03
0.00
1.4
1.9
25.31
18.88
ug/l
0.21
24
229
39
384
1.02
0.00
1.0
1.1
1.60
2.73
u/ml
1.00
13
192
94
946
0.99
0.00
2.1
2.2
21.29
21.24
s
0.03
76
819
20
195
1.03
0.00
1.2
1.2
—
56.47
—
0
11
53
529
1.00
0.00
1.1
1.1
5.12
5.73
u/ml
0.12
29
289
11
106
1.04
0.00
1.8
1.7
—
—
—
0
0
156
1561
1.00
0.00
1.6
1.6
—
—
—
0
0
27
266
1.02
0.00
2.9
2.1
—
—
—
0
0
34
338
1.01
0.00
1.2
1.4
66.45
67.25
mmol/l
0.04
29
282
44
442
1.00
0.00
1.6
1.4
0.32
0.40
nmol/l
0.36
33
347
10
103
0.97
0.00
1.2
1.1
—
—
—
0
0
20
203
0.99
0.00
1.1
1.1
—
—
—
0
0
15
147
1.02
0.00
11.1
6.8
—
—
—
0
0
17
167
1.02
0.00
1.0
1.1
0.53
3.70
u/ml
—
5
59
0
8
0.00
-0.00
0.0
1.4
—
2.20
—
0
8
0
5
0.00
-0.00
0.0
1.8
—
44.00
—
0
5
0
7
0.00
-0.00
0.0
1.0
—
46.40
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.7
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
8
82
0.98
-0.00
4.0
5.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
530.36
—
0
5
0
6
0.00
-0.00
0.0
8.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
72.60
—
0
5
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
239.20
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
5.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
108.17
—
0
6
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
8
82
0.98
-0.00
1.9
2.9
—
—
—
0
0
46
460
1.00
-0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
4.60
—
0
6
27
270
1.00
-0.00
2.2
1.5
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
1429.32
—
0
5

Mortality – FinRegistry

Association

Association between endpoint M13_OSTEOCHONDROPATHY and mortality.

Females

Parameter HR [95% CI] p-value
M13_OSTEOCHONDROPATHY 1.062 [0.88, 1.28] 0.522
Birth year 0.993 [0.98, 1.0] 0.122

During the follow-up period (1.1.1998 — 31.12.2019), 155 out of 4483 females with M13_OSTEOCHONDROPATHY died.

Males

Parameter HR [95% CI] p-value
M13_OSTEOCHONDROPATHY 0.818 [0.7, 0.96] 0.011
Birth year 0.989 [0.98, 1.0] 0.019

During the follow-up period (1.1.1998 — 31.12.2019), 211 out of 6001 males with M13_OSTEOCHONDROPATHY died.

Mortality risk

Mortality risk for people of age

years, who have M13_OSTEOCHONDROPATHY.

N-year risk Females Males
1 0.076% 0.175%
5 0.637% 0.997%
10 1.393% 2.652%
15 2.861% 4.997%
20 5.251% 8.44%

Relationships between endpoints

Index endpoint: M13_OSTEOCHONDROPATHY – Other osteochondropathies

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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