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Hypoplasia of dental enamel, including avohilmo

Endpoint Browser PheWeb

K11_HYPOPLASIA_ENAMEL

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — K00.40
  • Cause of death: ICD-10 — K00.40

2 out of 7 registries used, show all original rules.

291

4. Check minimum number of events

None

291

5. Include endpoints

None

291

6. Filter based on genotype QC (FinnGen only)

291

Control definitions (FinnGen only)

Control exclude
K11_MIH

Extra metadata

First used in FinnGen datafreeze
DF12

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 2239 1077 1161
Only index persons 1559 759 800
Unadjusted period prevalence (%)
Whole population 0.03 0.03 0.03
Only index persons 0.03 0.03 0.03
Median age at first event (years)
Whole population 8.72 8.93 8.50
Only index persons 10.24 10.43 10.06

-FinnGen-

Key figures

All Female Male
Number of individuals 291 143 148
Unadjusted period prevalence (%) 0.06 0.05 0.07
Median age at first event (years) 8.74 9.48 8.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
263
Matched controls
2628
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
+∞
323.0
263
*
127
Kela drug reimbursment
Transplant complication
113.5
107.4
112
17
H02AB09
ATC
hydrocortisone; systemic
35.2
103.7
140
82
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
38.6
96.4
125
60
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
39.3
88.9
114
50
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
112.9
85.8
90
12
H02AB04
ATC
methylprednisolone; systemic
42.5
84.6
106
41
Z94.0
ICD-10 Finland
Kidney transplant status
126.7
83.0
86
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
15.8
82.6
216
591
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
31.1
82.4
113
62
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
17.1
77.9
140
164
L04AX01
ATC
azathioprine; systemic
31.4
74.4
101
51
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
13.5
72.8
152
241
A11CC03
ATC
alfacalcidol; systemic
59.9
71.8
83
20
K03.66
ICD-10 Finland
Tooth plaque
11.9
71.4
173
364
WX408
NOMESCO Finland
General anesthesy, balanced
11.9
67.8
213
694
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
91.1
67.5
73
11
ZX120
NOMESCO Finland
Intravenous
15.4
65.6
120
136
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
205.8
63.1
63
*
XF602
NOMESCO Finland
Bloodpressure monitoring
60.1
61.5
71
16
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
104.9
60.1
64
8
L04AD01
ATC
ciclosporin; systemic
42.3
59.6
74
24
L04AA06
ATC
mycophenolic acid; systemic
51.4
58.0
69
18
EBA15
NOMESCO Finland
Extraction of large number of teeth
23.6
57.7
85
52
R4110
NOMESCO Finland
Physiotherapy
8.8
57.1
184
551
137
Kela drug reimbursment
Uraemia requiring dialysis
180.8
56.4
57
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
8.5
55.4
181
544
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.6
55.2
162
412
C08CA01
ATC
amlodipine; oral
28.6
54.6
75
36
205
Kela drug reimbursment
Chronic hypertension
34.2
54.4
71
28
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
16.3
53.7
92
84
B03XA01
ATC
erythropoietin; parenteral
168.9
53.1
54
*
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
20.0
51.4
80
56
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
9.2
51.1
128
245
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
96.4
50.1
54
7
K02.0
ICD-10 Finland
Caries limited to enamel
7.5
49.6
188
658
A12AA04
ATC
calcium carbonate; oral
84.3
49.3
54
8
SAA04
NOMESCO Finland
Special inverstigation of mouth
8.9
48.8
124
239
Z01.0
ICD-10 Finland
Examination of eyes and vision
7.4
47.2
147
382
602
Kela drug reimbursment
Children's severe malnutrition
13.4
47.1
88
95
K06.18
ICD-10 Finland
Another gingival hyperplasia
65.9
46.6
53
10
B05DA
ATC
Isotonic solutions
277.2
46.6
46
*
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
270.0
45.5
45
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
14.0
45.3
82
82
ZXA00
NOMESCO Finland
Right side
8.4
45.1
117
228
K00.41
ICD-10 Finland
Prenatal enamel hypoplasia
+∞
44.0
41
*
C08CA02
ATC
felodipine; oral
255.6
43.3
43
*
SAA03
NOMESCO Finland
Extended examination of mouth
13.3
43.1
247
1413
N04.80
ICD-10 Finland
Congenital nephrotic syndrome of the Finnish type
+∞
41.8
39
*
Z49.2
ICD-10 Finland
Other dialysis
465.0
41.3
40
*
TPH07
NOMESCO Finland
Cathetrisation of artery
8.4
41.0
103
186
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
24.4
40.6
58
30
SCE00
NOMESCO Finland
Fissure closure of tooth
6.2
40.5
150
463
TPH04
NOMESCO Finland
Cathetrisation of vein
7.0
40.4
122
288
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
102.4
40.2
43
5
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
10.3
40.1
86
118
L04AA01
ATC
[U] ciclosporin; systemic
124.3
40.0
42
*
WX882
NOMESCO Finland
High dependency care
7.1
39.8
117
265
A41.9
ICD-10 Finland
Sepsis, unspecified
19.0
39.1
61
41
KAC00
NOMESCO Finland
Nephrectomy
73.0
38.5
43
7
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
82.7
38.2
42
6
Z94.4
ICD-10 Finland
Liver transplant status
117.4
37.9
40
*
C03CA01
ATC
furosemide; systemic
15.0
37.7
65
56
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.2
37.2
127
344
XF400
NOMESCO Finland
ECG with 12 standard connections
5.7
37.2
146
469
5AB14
NOMESCO Finland
NA
94.0
37.0
40
5
K03.00
ICD-10 Finland
Approximal wear
16.9
36.8
60
45
Z99.2
ICD-10 Finland
Dependence on renal dialysis
110.5
35.8
38
*
K06.19
ICD-10 Finland
Gingival hyperplasia UNS
75.8
35.1
39
6
XW000
NOMESCO Finland
Bone marrow biopsy
18.5
35.0
55
37
V03AG01
ATC
sodium cellulose phosphate; systemic
34.9
34.2
44
15
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
8.3
34.2
84
141
TK800
NOMESCO Finland
Hemodialysis
73.6
34.0
38
6
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
10.8
33.8
69
84
RD210
NOMESCO Finland
NA
7.3
33.8
92
180
FM2CE
NOMESCO Finland
NA
6.6
33.4
100
223
N18.8
ICD-10 Finland
Other chronic renal failure
33.9
33.3
43
15
WW500
NOMESCO Finland
Blood transfusion
13.8
33.1
59
54
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
14.0
32.9
58
52
ZXA05
NOMESCO Finland
Left side
7.1
32.6
91
183
ZXA10
NOMESCO Finland
Bilateral
5.6
32.4
117
327
R50.9
ICD-10 Finland
Fever, unspecified
5.1
31.9
138
471
B05DB
ATC
Hypertonic solutions
181.3
31.4
32
*
Z49.1
ICD-10 Finland
Extracorporeal dialysis
181.3
31.4
32
*
TK820
NOMESCO Finland
Peritoneal dialysis
94.0
30.5
33
*
C07AB02
ATC
metoprolol; systemic
14.8
30.4
52
43
ZX199
NOMESCO Finland
Other rote
21.8
30.0
44
24
F59
ICD-10 Finland
Unspecified behavioural syndromes associated with physiological disturbances and physical factors
23.1
29.9
43
22
BE00A
NOMESCO Finland
NA
116.6
29.3
31
*
JN3CG
NOMESCO Finland
Extensive MRI examination of abdomen with high intensity magnet
21.5
28.5
42
23
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
11.5
28.5
55
59
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
5.6
28.1
96
244
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
4.6
28.0
131
467
C03DA01
ATC
spironolactone; oral
13.2
27.8
50
46
K03.64
ICD-10 Finland
Dental calculus supragingival
4.3
27.6
156
662
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.8
27.3
114
360
TPX10
NOMESCO Finland
Implantation of vascular injection port
20.6
26.2
39
22
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
6.0
25.7
80
179
4AA09
NOMESCO Finland
NA
77.8
25.3
28
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
25.0
25.1
35
16
XX4AW
NOMESCO Finland
NA
9.3
24.6
53
69
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
6.6
24.3
68
132
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
24.2
24.2
34
16
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
13.3
23.7
42
37
ZX121
NOMESCO Finland
Central venous catheter
19.3
22.5
34
20
C09AA02
ATC
enalapril; systemic
11.7
22.3
42
42
IGY02
NOMESCO Finland
Psychiatric monitoring contact
5.7
22.1
70
157
RS220
NOMESCO Finland
NA
9.6
21.5
45
55
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
3.6
21.3
154
747
SBB20
NOMESCO Finland
Tooth X-ray examination in conjunction with visit to dentist
65.7
21.3
24
*
J05AB01
ATC
aciclovir; systemic
5.9
21.2
64
135
Z94.1
ICD-10 Finland
Heart transplant status
40.9
21.2
26
7
V03AE01
ATC
polystyrene sulfonate; oral
227.2
20.9
21
*
TAB00
NOMESCO Finland
Lumbar puncture
8.8
20.8
46
62
BC00A
NOMESCO Finland
NA
35.8
20.6
26
8
WX402
NOMESCO Finland
General anaesthesia
3.8
20.3
114
445
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
9.1
20.3
44
57
EB1WA
NOMESCO Finland
NA
62.7
20.2
23
*
C09CA01
ATC
losartan; oral
14.3
20.0
34
27
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.1
19.9
93
310
A05AA02
ATC
ursodeoxycholic acid; oral
17.6
19.3
30
19
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.2
19.3
85
267
201
Kela drug reimbursment
Chronic cardiac insufficiency
12.8
19.1
34
30
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
4.9
19.1
69
178
Z01.2
ICD-10 Finland
Dental examination
3.8
19.0
211
1365
A02BC01
ATC
omeprazole; systemic
4.9
18.9
69
179
SDA03
NOMESCO Finland
Demanding parodonthologic therapy
4.0
18.8
88
291
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.6
18.7
73
203
K03.28
ICD-10 Finland
Other erosion of teeth
32.8
18.7
24
8
B34.9
ICD-10 Finland
Viral infection, unspecified
5.3
18.6
61
141
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
6.2
18.2
52
101
WX110
NOMESCO Finland
Local anesthesy
3.9
18.1
220
1495
XA800
NOMESCO Finland
Neuropsychological investigation
4.2
18.1
78
238
B03XA02
ATC
darbepoetin alfa; parenteral
102.0
17.8
19
*
6BA02
NOMESCO Finland
NA
20.4
17.7
26
14
RS221
NOMESCO Finland
NA
7.7
17.7
42
63
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
45.4
17.6
21
5
UDC00
NOMESCO Finland
Ear microscopy
5.1
17.5
59
140
H66.0
ICD-10 Finland
Acute suppurative otitis media
3.1
17.3
150
783
B01AA03
ATC
warfarin; systemic
10.9
17.2
33
34
F43.8
ICD-10 Finland
Other reactions to severe stress
23.8
17.2
24
11
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
12.0
17.0
31
29
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
67.9
17.0
19
*
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
37.8
16.9
21
6
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
3.8
16.9
223
1560
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
12.4
16.7
30
27
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
3.8
16.3
80
271
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
9.4
16.3
34
41
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
13.5
16.3
28
23
J01MA02
ATC
ciprofloxacin; systemic
5.8
16.1
48
98
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
17.1
16.1
25
16
WW200
NOMESCO Finland
Immunization
11.9
15.9
29
27
SDA02
NOMESCO Finland
Parodonthologic therapy
3.1
15.9
125
599
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
5.4
15.9
50
109
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
13.5
15.8
27
22
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.9
15.6
164
946
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
8.3
15.3
34
46
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.8
15.1
73
243
3A013
NOMESCO Finland
NA
60.3
15.0
17
*
A49.9
ICD-10 Finland
Bacterial infection, unspecified
8.2
14.8
33
45
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
13.7
14.7
25
20
XX4BW
NOMESCO Finland
NA
13.7
14.7
25
20
GD1LA
NOMESCO Finland
GD
+∞
14.7
14
*
TK823
NOMESCO Finland
Peritoneal permeability analysis
158.4
14.6
15
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
158.4
14.6
15
*
H02AB02
ATC
dexamethasone; systemic
11.4
14.6
27
26
XF600
NOMESCO Finland
Bloodpressure measurement
3.4
14.6
82
307
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.1
14.3
47
107
N18.0
ICD-10 Finland
End-stage renal disease
45.1
14.3
17
*
RK220
NOMESCO Finland
NA
13.8
14.2
24
19
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
11.4
14.1
26
25
K03.29
ICD-10 Finland
Erosion of teeth occupational
21.5
14.0
20
10
JJ9AE
NOMESCO Finland
Ultrasound examination of liver transplant
56.5
14.0
16
*
JAH00
NOMESCO Finland
Laparotomy
13.1
13.9
24
20
130
Kela drug reimbursment
Malignant tumour
13.9
13.7
23
18
C10AA03
ATC
pravastatin; oral
36.2
13.7
17
5
ZX090
NOMESCO Finland
Other technic of radiotherapy
+∞
13.7
13
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
9.4
13.6
28
33
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
27.4
13.6
18
7
J05AB11
ATC
valaciclovir; oral
7.8
13.5
31
44
RL140
NOMESCO Finland
NA
7.1
13.4
33
52
R4190
NOMESCO Finland
Nutritional therapy
3.2
13.4
83
331
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
9.6
13.4
27
31
B07.9
ICD-10 Finland
Verruca simplex
5.7
13.3
39
78
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
12.5
13.1
23
20
ZX131
NOMESCO Finland
Intrathecal
24.0
13.1
18
8
J02AC01
ATC
fluconazole; systemic
4.2
12.7
51
142
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
4.5
12.6
47
122
WX002
NOMESCO Finland
Sedation and analgesia
3.9
12.6
55
166
XF622
NOMESCO Finland
Measurement of minute volume of heart
12.5
12.6
22
19
ZX114
NOMESCO Finland
Intramuscular
9.4
12.3
25
29
L03AA02
ATC
filgrastim; parenteral
19.2
12.2
18
10
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
28.2
12.2
16
6
I15.8
ICD-10 Finland
Other secondary hypertension
28.2
12.2
16
6
C08CA05
ATC
nifedipine; systemic
28.2
12.2
16
6
783
NOMESCO Finland
NA
49.0
12.0
14
*
JAF10
NOMESCO Finland
Repair of umbilical hernia
15.6
12.0
19
13
1AB02
NOMESCO Finland
NA
13.4
11.8
20
16
TFJ02
NOMESCO Finland
Muscle biopsy of heart
24.2
11.7
16
7
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
68.0
11.7
13
*
K65.0
ICD-10 Finland
Acute peritonitis
68.0
11.7
13
*
H66.9
ICD-10 Finland
Otitis media, unspecified
2.6
11.6
117
621
IEP02
NOMESCO Finland
Child-centred family therapy
4.9
11.6
39
91
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
5.1
11.5
37
82
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
+∞
11.5
11
*
YNB20
NOMESCO Finland
Storage of stem cells for transplant
+∞
11.5
11
*
L04AA05
ATC
[U] tacrolimus; systemic
+∞
11.5
11
*
K07.30
ICD-10 Finland
Spacing, abnormal of tooth or teeth
2.8
11.5
92
427
JJC00
NOMESCO Finland
Allogenic transplantation of liver
125.2
11.5
12
*
WW409
NOMESCO Finland
Other aferesis
125.2
11.5
12
*
K07.24
ICD-10 Finland
Open bite
5.5
11.4
34
69
D89.89
ICD-10 Finland
Other specified disorders involving the immune mechanism, not elsewhere classified
36.8
11.4
14
*
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
5.6
11.1
32
63
GD1AD
NOMESCO Finland
Thorax CT examination
11.3
11.0
20
19
RK110
NOMESCO Finland
NA
10.3
11.0
21
22
SAB02
NOMESCO Finland
Oral and dental health check by dental hygienist or dental assistant
0.4
10.9
54
1085
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.6
10.8
23
29
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
13.7
10.8
18
14
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.4
10.8
40
103
UKC02
NOMESCO Finland
Cystoscopy
7.1
10.8
26
40
U14
ICPC
Kidney symptom/complaint
22.6
10.8
15
7
SFA40
NOMESCO Finland
Replacement of krone of tooth
6.7
10.8
27
44
TK810
NOMESCO Finland
Hemofiltration
62.6
10.7
12
*
KAB00
NOMESCO Finland
Biopsy of kidney or pelvis of kidney
62.6
10.7
12
*
N19
ICD-10 Finland
Unspecified kidney failure
62.6
10.7
12
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.9
10.7
75
318
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
6.9
10.6
26
41
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
6.3
10.6
28
49
AA1AD
NOMESCO Finland
CT of head and brain
5.0
10.5
34
76
Z94.2
ICD-10 Finland
Lung transplant status
+∞
10.5
10
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
+∞
10.5
10
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
2.6
10.4
92
448
N04.0
ICD-10 Finland
Nephrotic syndrome, minor glomerular abnormality
24.5
10.3
14
6
SFA10
NOMESCO Finland
Fillning on one surface of tooth
2.4
10.2
163
1071
TJF80
NOMESCO Finland
Ostomy education
12.0
10.2
18
16
WX302
NOMESCO Finland
Thoracal epidural anesthesy
9.7
10.2
20
22
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
15.4
10.1
16
11
KA1AE
NOMESCO Finland
Kidney ultrasound examination
8.2
10.1
22
29
TJW99
NOMESCO Finland
Other minor procedure in gastrointestinal endoscopy
41.8
10.0
12
*
A02BC05
ATC
esomeprazole; systemic
3.6
10.0
47
150
RS121
NOMESCO Finland
NA
7.0
10.0
24
37
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
6.0
10.0
27
49
L01BB02
ATC
mercaptopurine; oral
9.3
10.0
20
23
R11
ICD-10 Finland
Nausea and vomiting
3.2
9.9
55
199
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
21.0
9.9
14
7
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.4
9.9
193
1396
GAE10
NOMESCO Finland
Closure of previous incision of chest wall
8.4
9.8
21
27
EP1AE
NOMESCO Finland
Neck ultrasound examination
5.9
9.8
27
50
A04AA01
ATC
ondansetron; systemic, rectal
4.6
9.8
34
82
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.2
9.7
54
196
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
10.6
9.7
18
18
WX1PA
NOMESCO Finland
Total body mineral density measurement with Dual energy X-ray absorptiometry (DXA)
10.6
9.7
18
18
RT150
NOMESCO Finland
NA
5.3
9.6
29
60
A01AB09
ATC
miconazole; local oral
5.3
9.6
29
60
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.7
9.5
77
354
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
5.7
9.5
27
52
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.8
9.5
70
305
WX704
NOMESCO Finland
Intubation
4.7
9.5
32
75
JL5AG
NOMESCO Finland
Simple MRI examinaiton of bile and pancreas ducts with high intesity magnet
18.4
9.5
14
8
J01EA01
ATC
trimethoprim; systemic
3.7
9.4
42
128
2AX05
NOMESCO Finland
NA
+∞
9.4
9
*
K03.21
ICD-10 Finland
Erosion of teeth due to: persistent vomiting
+∞
9.4
9
*
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
2.3
9.4
149
964
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.3
9.4
49
170
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
3.2
9.4
52
188
XF404
NOMESCO Finland
Ambulatory ECG
3.9
9.3
39
113
RS210
NOMESCO Finland
NA
14.4
9.3
15
11
XKD00
NOMESCO Finland
Uroflowmetry
4.5
9.3
33
82
H52.0
ICD-10 Finland
Hypermetropia
3.9
9.3
38
108
K00.68
ICD-10 Finland
Other disturbance in the tooth eruption
3.9
9.3
38
108
FN1BB
NOMESCO Finland
Contrast angiography of heart and/or coronary arteries after bypass surgery
7.5
9.2
21
30
TJD20
NOMESCO Finland
Change of gastrostomy tube
7.0
9.2
22
34
JAB00
NOMESCO Finland
Division and ligature of inguinal hernia sac
5.9
9.2
25
46
1XC02
NOMESCO Finland
NA
38.1
9.1
11
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.6
8.9
74
344
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
4.4
8.9
32
80
Z31.5
ICD-10 Finland
Genetic counselling
3.3
8.9
46
158
B01.9
ICD-10 Finland
Varicella without complication
5.2
8.8
27
57
A06AD11
ATC
lactulose; oral
4.9
8.8
28
62
H26.3
ICD-10 Finland
Drug-induced cataract
51.7
8.7
10
*
C07AG02
ATC
carvedilol; oral
51.7
8.7
10
*
61
HP
Catheterization and pressure measurement of the left side of the heart
51.7
8.7
10
*
R1260
NOMESCO Finland
Evaluation of communicative skills
6.4
8.7
22
37
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
10.6
8.7
16
16
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
17.0
8.6
13
8
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.4
8.6
91
478
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
28.6
8.5
11
*
WW400
NOMESCO Finland
Plasmaferesis
28.6
8.5
11
*
K00.50
ICD-10 Finland
Dentinal dysplasia
20.8
8.5
12
6
TQW99
NOMESCO Finland
Other minor procedure on skin
7.1
8.5
20
30
A08.0
ICD-10 Finland
Rotaviral enteritis
6.6
8.5
21
34
ZX197
NOMESCO Finland
NA
92.9
8.5
9
*
K02.1
ICD-10 Finland
Caries of dentine
2.2
8.4
168
1177
K07.25
ICD-10 Finland
Anomalies of dental arch relationship
2.7
8.4
61
262
QXB05
NOMESCO Finland
Skin wound assessment, unspecified location
9.9
8.4
16
17
LC2AE
NOMESCO Finland
Ultrasound examination of uterus and parametria
5.0
8.4
26
56
ZX196
NOMESCO Finland
NA
+∞
8.4
8
*
K06.10
ICD-10 Finland
Gingival fibromatosis
+∞
8.4
8
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
+∞
8.4
8
*
H01AC01
ATC
somatropin; parenteral
3.9
8.4
34
96
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
15.1
8.3
13
9
A08.2
ICD-10 Finland
Adenoviral enteritis
15.1
8.3
13
9
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.1
8.3
134
857
J01DB01
ATC
cefalexin; oral
2.2
8.3
190
1415
RK230
NOMESCO Finland
NA
8.6
8.2
17
21
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
10.5
8.1
15
15
A08.1
ICD-10 Finland
Acute gastroenteropathy due to Norovirus
34.5
8.1
10
*
H52.2
ICD-10 Finland
Astigmatism
4.1
8.1
31
83
K05.11
ICD-10 Finland
Gingivitis (chronic) hyperplastic
22.8
8.1
11
5
SCF02
NOMESCO Finland
Preventive oral care by dental hygienist
3.0
8.0
48
180
Q23.4
ICD-10 Finland
Hypoplastic left heart syndrome
11.3
7.9
14
13
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
9.9
7.9
15
16
G04BE03
ATC
sildenafil; oral
9.9
7.9
15
16
H65.3
ICD-10 Finland
Chronic mucoid otitis media
2.6
7.9
61
272
TDM10
NOMESCO Finland
Puncture of maxillary antrum
7.8
7.8
17
23
C64.80
ICD-10 Finland
Wilms tumour
46.4
7.8
9
*
IEP03
NOMESCO Finland
Focused parental counselling
3.7
7.7
33
98
FQA00
NOMESCO Finland
Orthotopic transplantation of heart
19.0
7.7
11
6
31
HP
Congenital heart failure surgery
19.0
7.7
11
6
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
19.0
7.7
11
6
RS311
NOMESCO Finland
NA
12.4
7.7
13
11
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
12.4
7.7
13
11
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
3.4
7.6
36
116
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
2.4
7.5
72
357
NE1AA
NOMESCO Finland
Pelvis X-ray examination
5.9
7.5
20
36
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
6.3
7.5
19
32
H72.0
ICD-10 Finland
Central perforation of tympanic membrane
8.0
7.5
16
21
R62.0
ICD-10 Finland
Delayed milestone
2.9
7.5
46
177
RS222
NOMESCO Finland
NA
4.8
7.5
24
54
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
82.3
7.5
8
*
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
3.6
7.4
33
101
WZC30
NOMESCO Finland
Teaching
3.3
7.4
37
124
J01FF01
ATC
clindamycin; systemic
3.2
7.4
38
130
ZX112
NOMESCO Finland
Subcutaneous
6.6
7.4
18
29
C01AA05
ATC
digoxin; systemic
+∞
7.3
7
*
Z940, N0480
ICD-10 Finland
NA
+∞
7.3
7
*
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
+∞
7.3
7
*
N0480, Z940
ICD-10 Finland
NA
+∞
7.3
7
*
TKA05
NOMESCO Finland
Aspiration cytology of kidney
+∞
7.3
7
*
SPAT1262
SPAT
Handing over of treatment supplies
3.5
7.3
34
108
1XX02
NOMESCO Finland
NA
16.3
7.3
11
7
KF8AE
NOMESCO Finland
Ultrasound examination of scrotum
5.3
7.3
21
42
UJF32
NOMESCO Finland
Coloscopy
3.4
7.3
35
114
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
6.9
7.2
17
26
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
20.7
7.2
10
5
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
20.7
7.2
10
5
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
2.6
7.2
56
248
SAB03
NOMESCO Finland
Oral health check
0.5
7.2
71
1155
FDA00
NOMESCO Finland
Aortoplasty and aorto-pulmonary shunt for HLHS
12.5
7.1
12
10
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
9.2
7.1
14
16
FXA00
NOMESCO Finland
Total cardiopulmonary bypass in normothermia or moderate hypothermia at concurrent surgical procedure
3.5
7.1
32
99
J01MA12
ATC
levofloxacin; systemic
6.7
7.1
17
27
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.5
7.0
32
100
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
14.3
6.9
11
8
K03.22
ICD-10 Finland
Erosion of teeth due to: diet
11.4
6.9
12
11
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.1
6.8
25
65
3A077
NOMESCO Finland
NA
17.2
6.8
10
6
324
NOMESCO Finland
NA
17.2
6.8
10
6
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
41.1
6.8
8
*
8960/3-C64.9
ICD-O-3
Nephroblastoma, NOS, of kidney, NOS
41.1
6.8
8
*
2AX04
NOMESCO Finland
NA
23.2
6.7
9
*
A41.8
ICD-10 Finland
Other specified sepsis
23.2
6.7
9
*
Q44.21
ICD-10 Finland
Atresia of extrahepatic bile ducts
23.2
6.7
9
*
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
5.3
6.6
19
38
LC2DE
NOMESCO Finland
Demanding ultrsound examination of uterus, parametrium and lower part of abdomen with speciel methods
7.2
6.6
15
22
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
10.4
6.6
12
12
WX892
NOMESCO Finland
Monitored bed care
2.8
6.5
41
160
K01.14
ICD-10 Finland
Retained premolar with obstruction in the upper jaw
71.5
6.5
7
*
Q44.29
ICD-10 Finland
Atresia of bile ducts
14.8
6.4
10
7
RK260
NOMESCO Finland
NA
8.5
6.4
13
16
ZX100
NOMESCO Finland
Oral
8.5
6.4
13
16
WB133
NOMESCO Finland
Very demanding adjuvant cytostatic therapy
18.6
6.3
9
5
K07.20
ICD-10 Finland
Crossbite (anterior)(posterior)
3.1
6.3
35
125
JJC50
NOMESCO Finland
Resection of transplanted liver
+∞
6.3
6
*
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
+∞
6.3
6
*
JJC10
NOMESCO Finland
Allogenic partial transplantation of liver
27.4
6.3
8
*
9811/3-C42.1
ICD-O-3
B lymphoblastic leukemia/lymphoma, NOS, of bone marrow
27.4
6.3
8
*
TBW99
NOMESCO Finland
Other minor procedure in endocrine surgery
3.4
6.2
29
93
P85
ICPC
Mental retardation
5.1
6.2
18
37
K00.00
ICD-10 Finland
Hypodontia
3.4
6.2
28
88
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
12.9
6.1
10
8
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
12.9
6.1
10
8
FDF05
NOMESCO Finland
Percutaneous transluminal occlusion of aorto-pulmonary collaterals
12.9
6.1
10
8
RK320
NOMESCO Finland
NA
8.9
6.1
12
14
JDB10
NOMESCO Finland
Percutaneous gastrostomy
5.8
6.1
16
29
NF1AA
NOMESCO Finland
Hip X-ray examination
5.8
6.1
16
29
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
6.3
6.1
15
25
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
10.4
6.1
11
11
TQW80
NOMESCO Finland
Local dermatologic skincare
10.4
6.1
11
11
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
4.5
6.1
20
47
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.3
6.0
29
95
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
5.0
6.0
18
38
D64.9
ICD-10 Finland
Anaemia, unspecified
5.0
6.0
18
38

LabWAS

↥
OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
145
177
15.33
121.93
13.1
6.2
311.3
279.6
umol/l
1.89
145
169
151
247
11.63
99.95
6.2
4.3
59.7
61.5
e9/l
0.21
124
151
107
117
13.88
94.99
4.0
3.2
13.1
29.4
mu/l
1.61
107
110
170
339
10.66
94.62
8.7
2.7
12.9
14.4
umol/l
2.23
170
330
117
151
12.29
92.24
11.7
7.9
0.2
0.3
g/l
0.93
108
122
95
94
14.52
89.73
2.7
1.7
—
—
—
0
0
108
130
12.62
89.33
4.4
1.9
81.5
84.3
u/ml
—
5
7
179
402
9.97
88.68
41.6
9.5
7.5
4.8
mmol/l
13.54
179
396
108
133
12.32
87.77
4.3
1.8
—
—
—
0
0
54
23
28.60
76.97
3.2
2.4
—
—
—
0
0
132
268
8.18
69.29
21.1
7.4
5.4
8.0
umol/l
0.81
121
216
108
187
8.59
65.20
4.2
1.7
209.7
176.1
u/ml
0.39
70
72
196
633
7.42
63.06
32.0
8.6
—
—
—
0
0
43
19
26.38
60.04
3.7
3.4
—
—
—
0
0
176
537
6.76
59.39
9.9
3.0
600.1
616.4
mosm/kgh2o
0.39
169
450
153
417
6.63
58.16
16.0
3.7
7.4
7.4
ph
1.91
30
54
174
543
6.48
56.71
12.5
2.8
3.9
5.6
e6/l
2.09
169
464
165
491
6.45
56.70
7.7
2.8
—
—
—
0
0
194
699
6.33
52.77
29.5
7.3
5.4
5.1
kpa
1.18
194
682
172
561
6.05
52.41
9.0
3.0
—
—
—
0
0
195
714
6.25
51.80
31.9
7.4
1.2
1.3
mmol/l
0.07
183
564
134
354
6.16
51.76
2.0
1.8
1.2
1.3
mmol/l
0.34
134
331
195
717
6.21
51.45
31.9
7.4
5.8
5.9
kpa
1.28
195
697
82
140
7.76
49.09
2.2
1.7
—
—
—
0
0
226
987
6.77
47.57
30.1
8.3
—
—
—
0
0
180
651
5.63
47.41
25.3
7.1
84.7
83.7
%
0.24
180
646
193
766
5.51
44.64
16.0
3.9
0.1
0.2
e6/l
0.77
178
586
58
74
9.54
44.23
3.2
2.0
—
—
—
0
0
58
74
9.54
44.23
3.2
2.0
—
—
—
0
0
58
74
9.54
44.23
3.2
2.0
—
—
—
0
0
58
74
9.54
44.23
3.2
2.0
—
—
—
0
0
193
773
5.44
43.94
15.7
3.8
—
—
—
0
0
150
495
5.19
43.36
9.6
3.7
1.5
1.5
e6/l
0.05
129
305
52
60
10.33
42.74
4.4
3.8
21.0
26.3
umol/l
1.92
52
60
184
721
5.22
42.72
8.8
3.8
—
—
—
0
0
120
333
5.43
42.68
4.2
1.6
—
—
—
0
0
45
43
12.20
42.14
1.8
1.4
—
—
—
0
0
51
59
10.27
41.81
2.5
1.7
—
—
—
0
0
157
550
5.03
41.81
8.0
3.0
—
—
—
0
0
59
84
8.56
41.05
5.6
3.4
—
—
—
0
0
116
327
5.24
40.18
12.4
4.0
—
—
—
0
0
114
317
5.27
40.14
11.2
4.6
3.4
2.2
mg/l
0.42
101
214
207
934
5.21
39.02
21.2
4.7
13.6
41.2
e6/l
2.35
181
647
245
1267
6.91
38.96
32.6
8.9
—
—
—
0
0
42
41
11.80
38.69
1.5
1.4
—
—
—
0
0
192
823
4.92
38.54
18.0
3.9
11.1
18.8
e6/l
1.29
180
638
42
42
11.52
38.05
3.1
2.8
—
—
—
0
0
59
92
7.79
37.82
5.3
3.3
189.3
382.9
e6/l
3.12
43
68
58
91
7.71
36.94
5.7
3.2
66.9
68.7
%
0.19
58
91
88
209
5.60
36.90
3.2
2.6
7.0
5.5
iu/l
0.60
59
127
58
94
7.46
35.83
5.7
3.2
1.0
1.5
e9/l
2.50
45
70
127
419
4.60
35.48
10.0
3.9
1.1
1.2
inr
0.29
20
86
235
1236
5.68
34.76
56.7
9.5
1.2
1.2
mmol/l
0.22
229
1161
34
28
13.62
34.75
18.8
9.1
—
—
—
0
0
166
684
4.32
33.95
10.9
2.9
—
—
—
0
0
91
239
5.08
33.68
3.3
2.6
4.1
4.1
u/l
0.03
61
141
166
691
4.26
33.31
30.6
6.6
7.4
7.4
ph
0.30
22
17
55
91
7.22
33.24
5.7
3.3
—
—
—
0
0
153
605
4.22
32.92
30.7
6.2
—
—
—
0
0
61
120
6.17
31.02
8.9
5.7
0.4
0.6
%
0.43
33
37
40
50
9.12
30.63
15.3
5.5
—
—
—
0
0
70
160
5.44
30.23
3.3
1.7
—
—
—
0
0
228
1246
4.83
30.05
25.6
6.7
5.6
6.1
mmol/l
7.50
223
1181
51
87
6.90
29.82
5.6
3.2
24.5
26.1
%
0.36
51
87
214
1121
4.44
29.82
8.1
2.6
2.4
2.6
mmol/l
4.77
214
1052
258
1556
6.80
29.82
38.6
8.8
0.0
0.0
e9/l
3.90
242
1261
258
1560
6.77
29.61
38.7
8.8
0.6
0.6
e9/l
1.32
242
1264
215
1135
4.42
29.51
8.5
2.7
4.1
4.3
mmol/l
3.11
215
1089
57
110
6.20
29.50
8.1
4.9
0.3
0.6
%
0.81
27
26
40
53
8.59
29.20
2.9
2.0
—
—
—
0
0
259
1587
6.75
28.80
43.5
9.5
0.2
0.2
e9/l
1.58
246
1319
259
1596
6.66
28.35
38.6
8.8
2.1
2.3
e9/l
3.57
246
1337
51
92
6.51
28.20
5.6
3.1
384.0
532.3
e6/l
1.26
38
73
81
221
4.69
28.18
3.5
1.7
—
—
—
0
0
56
111
6.01
28.13
8.9
5.9
0.0
0.0
%
0.00
28
31
114
402
4.02
28.07
6.4
2.4
—
—
—
0
0
51
93
6.44
27.88
5.6
3.1
0.1
0.2
e9/l
2.73
38
74
250
1521
5.57
27.15
41.1
9.8
0.0
0.0
e9/l
0.16
230
1134
36
47
8.60
26.53
6.2
4.0
—
—
—
0
0
34
42
9.03
26.17
6.3
4.1
—
—
—
0
0
38
55
7.80
25.68
17.6
4.0
—
—
—
0
0
251
1569
5.36
25.33
37.8
8.7
50.0
48.1
%
1.87
251
1527
258
1648
5.99
25.30
46.6
10.0
3.2
3.3
e9/l
0.61
243
1338
254
1607
5.57
25.10
38.9
8.8
34.1
36.2
%
2.35
254
1561
92
303
3.98
24.57
3.7
1.6
—
—
—
0
0
34
46
8.24
24.29
6.9
3.8
3.4
2.6
e9/l
1.53
34
46
175
880
3.48
24.06
13.1
3.1
0.0
0.0
estimate
0.00
36
134
27
28
10.53
23.58
1.0
1.1
—
—
—
0
0
27
28
10.53
23.58
1.0
1.0
—
—
—
0
0
34
49
7.72
23.00
8.9
4.1
49.6
47.7
%
0.34
34
49
52
116
5.24
22.76
9.5
5.7
0.0
0.0
%
0.02
32
34
171
873
3.33
22.44
18.8
4.7
0.0
0.0
estimate
0.00
36
137
171
873
3.33
22.44
13.3
3.1
0.0
0.0
estimate
0.00
33
126
40
71
6.37
22.31
5.0
2.5
—
491.8
—
0
5
35
54
7.23
22.28
6.3
4.2
—
—
—
0
0
222
1338
3.78
21.95
18.8
3.9
—
—
—
0
0
102
386
3.53
21.83
2.1
1.7
—
—
—
0
0
28
35
8.75
21.25
17.8
11.2
4.8
4.9
kpa
0.33
28
35
28
35
8.75
21.25
17.8
10.1
11.1
8.6
kpa
5.15
28
35
28
35
8.75
21.25
17.8
11.2
0.8
1.5
mmol/l
0.93
14
20
137
641
3.15
20.38
4.3
3.8
2.9
2.5
mg/l
1.31
127
570
209
1257
3.35
19.78
17.4
3.3
7.0
102.3
e6/l
—
10
10
82
287
3.59
19.58
2.2
1.5
—
—
—
0
0
28
40
7.64
19.00
2.9
2.4
15.3
14.0
umol/l
0.20
28
40
19
17
11.89
18.17
2.8
2.4
—
—
—
0
0
36
71
5.65
17.92
24.6
8.3
1.2
1.2
mmol/l
0.34
36
60
24
32
8.08
17.22
2.2
1.6
—
—
—
0
0
20
21
10.15
17.19
2.1
2.4
—
—
—
0
0
21
26
8.63
15.96
1.5
1.3
—
—
—
0
0
33
67
5.43
15.88
10.9
4.2
—
—
—
0
0
92
394
2.95
15.28
2.1
1.6
—
—
—
0
0
14
10
14.66
15.14
1.3
1.2
—
—
—
0
0
17
17
10.56
15.05
9.6
4.8
—
—
—
0
0
56
188
3.45
13.93
3.1
2.2
9.6
8.7
nmol/l
0.29
42
134
75
302
3.00
13.77
2.4
1.5
265.0
707.7
titre
1.29
16
39
88
391
2.79
13.45
21.6
4.8
—
—
—
0
0
18
23
8.28
13.30
2.5
3.1
1.2
1.1
umol/l
0.05
18
23
26
50
5.61
13.22
2.3
2.6
26.5
38.6
mmol/l
1.40
26
50
30
68
4.80
12.70
5.3
2.6
130.5
137.5
g/l
1.29
25
57
33
81
4.47
12.68
1.2
1.2
—
—
—
0
0
30
69
4.73
12.48
27.6
15.2
—
—
—
0
0
18
25
7.61
12.41
1.0
1.4
—
—
—
0
0
39
117
3.69
11.42
24.7
13.4
-0.3
-0.3
mmol/l
0.01
31
97
12
11
11.34
11.13
2.9
1.6
32.4
33.7
pg
0.38
12
11
42
135
3.47
11.09
1.3
1.1
—
—
—
0
0
28
67
4.52
11.08
27.9
17.3
70.5
72.2
%
0.22
28
67
31
81
4.16
10.98
1.6
1.2
—
—
—
0
0
22
43
5.45
10.97
16.4
9.7
—
—
—
0
0
63
260
2.82
10.87
7.6
3.3
616.0
1640.4
ng/l
1.12
43
158
16
23
7.30
10.68
1.0
1.3
—
—
—
0
0
179
1193
2.30
10.62
4.1
2.1
5.2
5.4
mmol/l
1.65
172
1077
33
94
3.83
10.39
27.6
15.7
23.7
23.8
mmol/l
0.12
33
94
14
18
8.12
10.23
4.6
4.9
247.4
234.2
ug/l
0.07
14
18
95
496
2.36
9.98
2.3
2.0
—
—
—
0
0
16
25
6.71
9.91
1.4
1.1
—
—
—
0
0
18
32
5.93
9.87
1.1
1.4
—
—
—
0
0
52
207
2.84
9.53
5.4
3.7
271.0
139.9
mg/l
0.68
46
165
44
160
3.06
9.47
2.0
1.2
—
—
—
0
0
18
34
5.58
9.28
1.6
1.6
13.8
17.2
nmol/l
—
5
12
271
2275
3.78
8.57
32.9
6.8
—
—
—
0
0
12
16
7.78
8.47
1.5
1.5
15.7
16.7
umol/l
0.32
12
16
24
63
4.06
8.43
3.2
2.5
—
—
—
0
0
40
148
2.97
8.33
1.6
1.5
—
—
—
0
0
15
27
5.80
8.10
9.4
3.4
30.1
23.7
ug/l
0.44
15
27
30
95
3.41
8.07
1.6
1.5
—
—
—
0
0
12
18
6.91
7.66
2.0
1.1
—
—
—
0
0
12
18
6.91
7.66
2.0
1.1
—
—
—
0
0
12
18
6.91
7.66
2.0
1.1
—
—
—
0
0
10
12
8.59
7.62
1.6
1.3
—
—
—
0
0
14
25
5.83
7.62
1.8
1.4
—
—
—
0
0
18
41
4.61
7.54
1.1
1.3
—
—
—
0
0
10
5
20.63
7.18
1.6
1.0
5.9
—
pmol/l
—
5
0
10
5
20.63
7.18
15.7
10.2
—
—
—
0
0
72
380
2.19
7.10
2.1
1.4
104.0
96.6
pmol/l
0.86
38
178
19
49
4.08
6.82
33.3
20.2
10.4
12.0
%
1.89
19
49
11
9
12.64
6.63
1.8
2.7
—
—
—
0
0
11
9
12.64
6.63
2.2
2.7
—
—
—
0
0
280
2478
4.44
6.52
73.7
13.5
36.5
39.2
%
13.11
272
2268
33
126
2.83
6.48
15.6
3.2
—
—
—
0
0
10
15
6.87
6.35
3.9
2.5
—
—
—
0
0
30
115
2.79
5.85
2.1
1.3
0.2
0.2
g/l
0.18
30
110
11
20
5.68
5.85
1.8
1.3
—
—
—
0
0
25
87
3.05
5.78
36.7
17.4
0.8
0.7
%
0.27
25
87
25
88
3.01
5.67
36.7
17.2
94.4
95.6
%
0.37
25
88
30
117
2.74
5.67
2.1
1.3
1.1
1.2
g/l
1.01
30
111
23
77
3.16
5.67
38.8
16.5
—
—
—
0
0
12
25
4.96
5.54
4.8
3.6
—
—
—
0
0
25
90
2.94
5.46
11.4
4.3
—
—
—
0
0
70
404
1.96
5.31
18.6
3.1
0.0
0.0
estimate
0.00
34
133
14
35
4.15
5.23
1.1
1.3
2.0
3.1
u/ml
—
9
21
156
1159
1.75
5.15
2.8
1.7
1.6
1.5
g/l
0.26
114
512
24
88
2.88
5.08
37.5
17.2
0.9
1.1
%
0.79
24
88
25
94
2.82
5.06
11.6
4.2
525.4
584.6
e6/l
0.04
20
70
25
94
2.82
5.06
11.6
4.2
6.0
6.4
e6/l
0.02
20
69
44
217
2.21
5.05
4.1
2.3
106.2
16.5
ng/l
1.03
29
78
19
62
3.21
4.89
8.2
3.6
—
—
—
0
0
25
96
2.75
4.87
1.7
1.8
—
4.5
—
0
5
266
2356
2.50
4.84
57.7
9.6
20.2
24.5
mg/l
1.82
234
1479
100
671
1.75
4.63
1.8
1.5
—
—
—
0
0
7
5
14.29
4.60
3.0
2.6
—
—
—
0
0
7
5
14.29
4.60
3.1
2.4
0.3
26.4
u/field
—
7
5
7
5
14.29
4.60
3.0
2.6
106.7
106.4
mmol/l
—
7
5
24
95
2.66
4.42
6.3
2.9
39.8
35.2
umol/l
0.53
24
87
22
84
2.75
4.34
13.0
4.6
—
—
—
0
0
9
13
7.10
4.19
1.9
2.8
1813.4
1706.8
u/ml
—
9
13
7
7
10.21
4.03
6.1
2.7
0.1
0.1
e9/l
—
7
7
7
7
10.21
4.03
3.0
2.1
4.6
3.7
mmol/l
—
7
7
63
385
1.81
3.94
16.0
2.7
—
—
—
0
0
23
95
2.54
3.91
12.4
4.2
244.2
329.5
mg/l
1.21
23
95
6
5
12.21
3.78
1.5
1.2
156.7
208.6
mmol/l
—
6
5
10
26
3.95
3.55
1.1
1.1
—
—
—
0
0
32
161
2.11
3.50
2.0
1.4
—
—
—
0
0
16
60
2.76
3.28
1.4
1.3
—
—
—
0
0
7
11
6.49
3.20
1.1
1.4
28.3
23.8
u/l
—
7
11
44
258
1.83
3.13
3.2
1.8
—
—
—
0
0
65
427
1.67
3.13
13.0
2.5
1.0
1.0
kg/l
—
9
87
12
39
3.17
3.12
1.2
1.2
—
—
—
0
0
9
21
4.39
3.02
5.7
4.8
1.8
1.5
mmol/l
—
9
21
9
21
4.39
3.02
2.2
2.4
—
—
—
0
0
17
69
2.55
3.02
1.2
1.4
372.0
361.8
ug/g
—
10
38
15
57
2.72
3.01
18.7
7.5
—
—
—
0
0
5
5
10.14
2.99
1.2
2.6
—
—
—
0
0
12
42
2.94
2.78
1.2
1.1
—
—
—
0
0
5
6
8.45
2.76
1.6
2.0
—
—
—
0
0
218
1917
1.55
2.65
4.5
3.6
2.2
2.0
mu/l
1.10
213
1803
18
81
2.30
2.60
1.5
1.0
—
—
—
0
0
8
20
4.08
2.58
3.1
1.9
—
—
—
0
0
15
62
2.50
2.58
4.9
1.8
—
—
—
0
0
5
7
7.24
2.56
1.0
1.0
—
—
—
0
0
5
7
7.24
2.56
1.2
1.0
154.8
154.0
nmol/l
—
5
7
33
190
1.83
2.50
4.6
3.2
—
—
—
0
0
7
16
4.45
2.49
1.1
1.1
—
—
—
0
0
18
83
2.25
2.46
4.6
6.4
2.8
2.0
ug/l
0.55
18
83
78
566
1.52
2.44
4.5
3.5
196.3
77.1
ug/g
0.73
73
456
103
793
1.46
2.40
3.7
2.0
—
—
—
0
0
5
9
5.63
2.22
1.2
1.4
—
—
—
0
0
14
61
2.36
2.18
1.4
1.1
—
—
—
0
0
5
10
5.07
2.08
1.4
1.2
—
—
—
0
0
5
11
4.60
1.95
1.2
1.5
—
—
—
0
0
18
93
2.00
1.89
1.8
1.2
—
—
—
0
0
7
22
3.23
1.89
7.7
5.5
—
—
—
0
0
6
17
3.58
1.84
1.2
1.2
71.7
74.2
%
—
6
17
6
17
3.58
1.84
1.2
1.2
384.5
471.2
mu/l
—
6
17
18
94
1.98
1.84
1.7
1.2
—
—
—
0
0
14
69
2.08
1.67
2.4
1.5
—
—
—
0
0
5
14
3.61
1.62
1.2
1.1
—
—
—
0
0
5
14
3.61
1.62
1.2
1.1
—
—
—
0
0
7
27
2.63
1.52
1.0
1.0
—
—
—
0
0
94
765
1.34
1.49
2.2
1.9
—
—
—
0
0
5
16
3.16
1.44
1.2
1.1
—
—
—
0
0
5
16
3.16
1.44
1.0
1.0
—
—
—
0
0
6
22
2.76
1.44
1.7
1.5
—
—
—
0
0
7
29
2.45
1.40
1.0
1.3
—
—
—
0
0
5
17
2.97
1.36
1.2
1.1
—
—
—
0
0
8
34
2.39
1.30
1.1
1.0
—
—
—
0
0
8
37
2.19
1.22
1.1
1.1
—
—
—
0
0
5
20
2.53
1.15
12.6
3.0
—
—
—
0
0
40
298
1.40
1.10
1.7
1.8
—
—
—
0
0
8
41
1.98
1.09
3.1
2.4
3.6
2.5
nmol/l
—
8
36
20
295
0.65
1.03
1.0
1.2
0.4
5.3
u/ml
—
6
101
5
23
2.19
0.98
1.0
1.3
10.2
8.0
umol/l
—
5
23
6
30
2.02
0.87
1.5
1.0
—
—
—
0
0
0
25
0.00
0.79
0.0
1.4
—
—
—
0
0
5
27
1.87
0.68
1.0
1.0
171.0
161.4
g/l
—
5
27
5
93
0.53
0.68
1.0
1.4
—
—
—
0
0
22
164
1.37
0.64
3.8
2.7
26527.2
4826.4
u/l
—
5
48
20
148
1.38
0.61
1.3
1.1
—
—
—
0
0
0
21
0.00
0.60
0.0
1.0
—
—
—
0
0
21
160
1.34
0.55
1.9
1.5
—
—
—
0
0
9
62
1.47
0.53
1.0
1.3
—
—
—
0
0
14
100
1.42
0.53
1.1
1.3
0.5
9.8
u/ml
—
9
86
27
218
1.26
0.48
1.2
1.2
11.2
15.0
iu/ml
—
5
40
7
46
1.53
0.48
1.1
1.2
—
—
—
0
0
26
318
0.80
0.46
1.5
1.3
1.8
4.2
u/ml
1.07
17
225
24
295
0.80
0.45
1.2
1.2
0.1
1.2
u/ml
2.80
17
231
9
130
0.68
0.44
1.0
1.0
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
0
16
0.00
0.41
0.0
2.8
—
1.3
—
0
11
0
17
0.00
0.41
0.0
1.2
—
—
—
0
0
0
17
0.00
0.41
0.0
1.2
—
0.5
—
0
17
25
300
0.82
0.39
1.2
1.2
0.5
7.0
u/ml
9.48
18
243
6
41
1.47
0.36
2.3
2.5
0.6
1.2
ug/l
—
6
33
19
232
0.81
0.35
1.6
2.1
—
—
—
0
0
6
44
1.37
0.34
3.7
1.6
—
—
—
0
0
12
91
1.33
0.34
2.9
1.8
—
—
—
0
0
7
52
1.35
0.31
1.1
1.4
—
—
—
0
0
7
52
1.35
0.31
1.1
1.4
—
—
—
0
0
7
54
1.30
0.30
1.3
1.5
—
—
—
0
0
13
103
1.27
0.28
1.1
1.1
—
—
—
0
0
21
247
0.84
0.28
1.6
2.1
—
—
—
0
0
9
117
0.76
0.28
1.2
1.2
—
—
—
0
0
16
131
1.23
0.28
1.8
1.6
—
—
—
0
0
8
67
1.20
0.26
1.0
1.0
19.2
19.5
mmol/l
—
8
67
8
67
1.20
0.26
1.0
1.0
—
—
—
0
0
21
245
0.85
0.26
1.6
2.0
—
—
—
0
0
21
245
0.85
0.26
1.6
2.0
—
—
—
0
0
21
242
0.86
0.23
1.6
2.0
—
—
—
0
0
43
392
1.11
0.22
1.1
1.2
—
60.8
—
0
6
5
40
1.25
0.22
1.8
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
11.4
—
670.3
—
0
11
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
4.2
—
0.4
—
0
10
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
15
126
1.20
0.21
1.5
2.2
4.0
4.1
e9/l
0.06
15
121
0
12
0.00
0.21
0.0
1.2
—
—
—
0
0
19
205
0.92
0.08
1.5
2.1
—
—
—
0
0
56
579
0.96
0.07
1.2
1.2
—
—
—
0
0
8
90
0.89
0.07
1.3
1.2
—
—
—
0
0
124
1220
1.03
0.06
1.6
2.0
5.6
4.7
u/ml
0.07
15
184
12
130
0.92
0.04
1.1
1.1
—
—
—
0
0
17
171
0.99
0.00
2.1
2.5
—
—
—
0
0
14
137
1.02
0.00
1.6
2.4
—
—
—
0
0
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
0.00
0.0
2.8
—
—
—
0
0
9
95
0.95
0.00
1.3
1.2
—
—
—
0
0
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
9
98
0.92
0.00
1.7
1.9
—
—
—
0
0
0
6
0.00
0.00
0.0
4.7
—
421.2
—
0
6
5
59
0.84
0.00
1.0
1.1
—
—
—
0
0
0
6
0.00
0.00
0.0
11.5
—
—
—
0
0

Mortality – FinRegistry

↥

Association

Association between endpoint K11_HYPOPLASIA_ENAMEL and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_HYPOPLASIA_ENAMEL.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

↥

Index endpoint: K11_HYPOPLASIA_ENAMEL – Hypoplasia of dental enamel, including avohilmo

GWS hits: 2

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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